Gene Symbol | PRX1 |
Entrez Gene ID | 852215 |
Full Name | thioredoxin peroxidase PRX1 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » PRX1 cDNA ORF clone
Gene Symbol | PRX1 |
Entrez Gene ID | 852215 |
Full Name | thioredoxin peroxidase PRX1 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001178304.1 | NP_009489.1 | thioredoxin peroxidase PRX1 |
Homo sapiens (human) | PRDX6 | NP_004896.1 |
Canis lupus familiaris (dog) | PRDX6 | XP_537190.3 |
Kluyveromyces lactis | KLLA0E20285g | XP_454869.1 |
Oryza sativa (rice) | Os07g0638300 | NP_001060407.1 |
Saccharomyces cerevisiae (baker's yeast) | PRX1 | NP_009489.1 |
Arabidopsis thaliana (thale cress) | PER1 | NP_175247.1 |
PRDX6 | XP_001101473.1 | |
Bos taurus (cattle) | PRDX6 | NP_777068.1 |
Rattus norvegicus (Norway rat) | Prdx6 | NP_446028.1 |
Gallus gallus (chicken) | PRDX6 | NP_001034418.1 |
Danio rerio (zebrafish) | prdx6 | NP_957099.1 |
Caenorhabditis elegans (roundworm) | prdx-6 | NP_741287.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_08256 | XP_003715830.1 |
Neurospora crassa | NCU06031 | XP_959621.1 |
Oryza sativa (rice) | Os07g0638400 | NP_001060408.1 |
Pan troglodytes (chimpanzee) | PRDX6 | XP_524972.2 |
Mus musculus (house mouse) | Prdx6 | NP_031479.1 |
Drosophila melanogaster (fruit fly) | Prx6005 | NP_523463.2 |
Anopheles gambiae (African malaria mosquito) | TPX5 | XP_308753.2 |
Eremothecium gossypii | AGOS_AGR368W | NP_987034.2 |
Xenopus tropicalis (tropical clawed frog) | prdx6 | NP_989102.1 |
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
Complete DNA sequence of yeast chromosome II.
Feldmann H, Aigle M, Aljinovic G, Andr? B, Baclet MC, Barthe C, Baur A, B?cam AM, Biteau N, Boles E, Brandt T, Brendel M, Br?ckner M, Bussereau F, Christiansen C, Contreras R, Crouzet M, Cziepluch C, D?molis N, Delaveau T, Doignon F, Domdey H, D?sterhus S, Dubois E, Dujon B, El Bakkoury M, Entian KD, Feurmann M, Fiers W, Fobo GM, Fritz C, Gassenhuber H, Glandsdorff N, Goffeau A, Grivell LA, de Haan M, Hein C, Herbert CJ, Hollenberg CP, Holmstr?m K, Jacq C, Jacquet M, Jauniaux JC, Jonniaux JL, Kalles?e T, Kiesau P, Kirchrath L, K?tter P, Korol S, Liebl S, Logghe M, Lohan AJ, Louis EJ, Li ZY, Maat MJ, Mallet L, Mannhaupt G, Messenguy F, Miosga T, Molemans F, M?ller S, Nasr F, Obermaier B, Perea J, Pi?rard A, Piravandi E, Pohl FM, Pohl TM, Potier S, Proft M, Purnelle B, Ramezani Rad M, Rieger M, Rose M, Schaaff-Gerstenschl?ger I, Scherens B, Schwarzlose C, Skala J, Slonimski PP, Smits PH, Souciet JL, Steensma HY, Stucka R, Urrestarazu A, van der Aart QJ, van Dyck L, Vassarotti A, Vetter I, Vierendeels F, Vissers S, Wagner G, de Wergifosse P, Wolfe KH, Zagulski M, Zimmermann FK, Mewes HW, Kleine K
The EMBO journal13(24)5795-809(1994 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Oct1 cleaved eight amino acid residues from the N-terminal region of Prx1 inside the matrix, without interfering with its peroxidase activity in vitro
Title: Proteolytic cleavage by the inner membrane peptidase (IMP) complex or Oct1 peptidase controls the localization of the yeast peroxiredoxin Prx1 to distinct mitochondrial compartments.
Prx1p is fairly well protected from overoxidation, questioning its role in a floodgate mechanism for H2O2 signaling
Title: Glutathione Is the Resolving Thiol for Thioredoxin Peroxidase Activity of 1-Cys Peroxiredoxin Without Being Consumed During the Catalytic Cycle.
these findings suggest that Srx1 regulates YPrx1 function and structure in yeast cells through a direct interaction.
Title: Reversal of 2-Cys peroxiredoxin oligomerization by sulfiredoxin.
Mitochondrial Prx1 functions as a redox signaling molecule that oxidizes Trx3 and promotes apoptosis.
Title: Oxidation of the yeast mitochondrial thioredoxin promotes cell death.
specific functions of two interacting redoxins: dually localized glutaredoxin 2 (Grx2p) and mitochondrial peroxiredoxin 1 (Prx1p)
Title: Biosynthetic and iron metabolism is regulated by thiol proteome changes dependent on glutaredoxin-2 and mitochondrial peroxiredoxin-1 in Saccharomyces cerevisiae.
The following PRX1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PRX1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi01647 | |
Clone ID Related Accession (Same CDS sequence) | NM_001178304.1 | |
Accession Version | NM_001178304.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 786bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | thioredoxin peroxidase PRX1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001134). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGTTTAGTA GAATTTGTAG CGCTCAATTA AAGAGGACGG CATGGACCCT TCCTAAGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_009489.1 |
CDS | 1..786 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001178304.1 |
1 | ATGTTTAGTA GAATTTGTAG CGCTCAATTA AAGAGGACGG CATGGACCCT TCCTAAGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Life with 6000 genes. |
Complete DNA sequence of yeast chromosome II. |