Gene Symbol | RPN12 |
Entrez Gene ID | 850613 |
Full Name | proteasome regulatory particle lid subunit RPN12 |
Synonyms | NIN1 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » RPN12 cDNA ORF clone
Gene Symbol | RPN12 |
Entrez Gene ID | 850613 |
Full Name | proteasome regulatory particle lid subunit RPN12 |
Synonyms | NIN1 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001180017.1 | NP_116710.1 | proteasome regulatory particle lid subunit RPN12 |
Homo sapiens (human) | PSMD8 | NP_002803.2 |
Drosophila melanogaster (fruit fly) | Rpn12 | NP_648904.1 |
Schizosaccharomyces pombe (fission yeast) | rpn12 | NP_596750.2 |
Neurospora crassa | NCU10067 | XP_957882.1 |
Arabidopsis thaliana (thale cress) | RPN12a | NP_176633.1 |
Oryza sativa (rice) | Os07g0435100 | NP_001059500.1 |
Pan troglodytes (chimpanzee) | PSMD8 | NP_001238915.1 |
LOC721897 | XP_001118092.2 | |
Canis lupus familiaris (dog) | PSMD8 | XP_533681.1 |
Bos taurus (cattle) | PSMD8 | NP_001030283.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP002606 | XP_312329.4 |
Rattus norvegicus (Norway rat) | Psmd8 | NP_001094301.1 |
Caenorhabditis elegans (roundworm) | rpn-12 | NP_496489.1 |
Saccharomyces cerevisiae (baker's yeast) | RPN12 | NP_116710.1 |
Eremothecium gossypii | AGOS_AFR278W | NP_985825.1 |
Mus musculus (house mouse) | Psmd8 | NP_080821.3 |
Danio rerio (zebrafish) | psmd8 | NP_001002131.1 |
Kluyveromyces lactis | KLLA0D11374g | XP_453568.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_03512 | XP_003716407.1 |
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
Analysis of the nucleotide sequence of chromosome VI from Saccharomyces cerevisiae.
Murakami Y, Naitou M, Hagiwara H, Shibata T, Ozawa M, Sasanuma S, Sasanuma M, Tsuchiya Y, Soeda E, Yokoyama K
Nature genetics10(3)261-8(1995 Jul)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Assimilation of the final lid subunit of the 26S proteasome, Rpn12, triggers a large-scale conformational remodeling of the nascent lid that drives regulatory particles assembly, in part by relieving steric clash with the base.
Title: A Single ? Helix Drives Extensive Remodeling of the Proteasome Lid and Completion of Regulatory Particle Assembly.
Data show that proteasome subunits Rpt1, Rpt4, Rpn8, Rpn12, Pre6, and Pre10 are recruited to GAL10 rapidly upon galactose induction.
Title: Similar temporal and spatial recruitment of native 19S and 20S proteasome subunits to transcriptionally active chromatin.
Mass spectra of the intact lid complex from Saccharomyces cerevisiae show that eight of the nine subunits are present stoichiometrically and that a stable tetrameric subcomplex forms in solution.
Title: Structural organization of the 19S proteasome lid: insights from MS of intact complexes.
19S RP modulates SAGA complex using its ATPase components, thereby facilitating subsequent transcription events at promoters.
Title: The proteasome regulatory particle alters the SAGA coactivator to enhance its interactions with transcriptional activators.
The following RPN12 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RPN12 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi00290 | |
Clone ID Related Accession (Same CDS sequence) | NM_001180017.1 | |
Accession Version | NM_001180017.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 825bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | proteasome regulatory particle lid subunit RPN12 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001138). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGCCCTCGT TAGCCGAATT GACCAAGTCG TTAAGCATAG CCTTTGAAAA CGGCGATTAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_116710.1 |
CDS | 1..825 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001180017.1 |
1 | ATGCCCTCGT TAGCCGAATT GACCAAGTCG TTAAGCATAG CCTTTGAAAA CGGCGATTAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Life with 6000 genes. |
Analysis of the nucleotide sequence of chromosome VI from Saccharomyces cerevisiae. |