Slco1c1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Slco1c1
Entrez Gene ID	84511
Full Name	solute carrier organic anion transporter family, member 1c1
Synonyms	Bsat1,Oatp14,Slc21a14
General protein information	Preferred Names solute carrier organic anion transporter family, member 1c1 Names solute carrier organic anion transporter family member 1C1 BBB-specific anion transporter type 1 blood-brain barrier specific anion transporter blood-brain barrier-specific anion transporter 1 solute carrier family 21 (organic anion transporter), member 14 solute carrier family 21 member 14 thyroxine transporter
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 4 Map Location: 4q44
Summary	catalyzes high affinity transport of sulfated bile acids into hepatocytes [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_053441.1	NP_445893.1	solute carrier organic anion transporter family member 1C1

Pathways from BioSystems

Homologies

Homo sapiens (human)	SLCO1C1	NP_059131.1
	SLCO1C1	XP_001097287.1
Canis lupus familiaris (dog)	SLCO1C1	XP_852867.1
Mus musculus (house mouse)	Slco1c1	NP_067446.1
Gallus gallus (chicken)	SLCO1C1	NP_001034186.1
Xenopus tropicalis (tropical clawed frog)	slco1c1	XP_002943709.2
Pan troglodytes (chimpanzee)	SLCO1C1	XP_003313583.1
Rattus norvegicus (Norway rat)	Slco1c1	NP_445893.1
Bos taurus (cattle)	SLCO1C1	NP_001178438.1
Danio rerio (zebrafish)	slco1c1	NP_001038462.2

Gene Ontology
Bibliography

Related articles in PubMed

Prenatal exposure to brain-specific anion transporter-1-specific monoclonal antibodies impairs cognitive function in post-natal life.
Zubkov EA, Zorkina YA, Gurina OI, Melnikov PA, Morozova AY, Chekhonin VP
Neuropeptides65100-105(2017 Oct)

Antidepressant behavior in thyroidectomized Wistar rats is induced by hippocampal hypothyroidism.
da Concei??o RR, Laureano-Melo R, Oliveira KC, de Carvalho Melo MC, Kasamatsu TS, de Barros Maciel RM, de Souza JS, Giannocco G
Physiology & behavior157158-64(2016 Apr)

Parallel regulation of thyroid hormone transporters OATP1c1 and MCT8 during and after endotoxemia at the blood-brain barrier of male rodents.
Wittmann G, Szabon J, Moh?csik P, Nouriel SS, Gereben B, Fekete C, Lechan RM
Endocrinology156(4)1552-64(2015 Apr)

Expression of organic anion transporting polypeptide 1c1 and monocarboxylate transporter 8 in the rat placental barrier and the compensatory response to thyroid dysfunction.
Sun YN, Liu YJ, Zhang L, Ye Y, Lin LX, Li YM, Yan YQ, Chen ZP
PloS one9(4)e96047(2014)

Organ, cellular, and subcellular localization of brain-specific anion transporter BSAT1.
Baklaushev VP, Kardashova KSh, Gurina OI, Yusubaliyeva GM, Zorkina YA, Chekhonin VP
Bulletin of experimental biology and medicine155(4)491-7(2013 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

This study demonstrated that reduction of the Mct8 mRNA expression in hippocampus of thyroidectomized Wistar rats.
Title: Antidepressant behavior in thyroidectomized Wistar rats is induced by hippocampal hypothyroidism.

The data demonstrate that OATP1c1 and MCT8 expression are regulated in a parallel manner during inflammation at the blood-brain barrier of rodents.
Title: Parallel regulation of thyroid hormone transporters OATP1c1 and MCT8 during and after endotoxemia at the blood-brain barrier of male rodents.

The coordinated effects of Oatp1c1, Mct8, D2 and D3 in the placental barrier may regulate both transplacental TH passage and the development of trophoblast cells during thyroid dysfunction throughout the pregnancy.
Title: Expression of organic anion transporting polypeptide 1c1 and monocarboxylate transporter 8 in the rat placental barrier and the compensatory response to thyroid dysfunction.

Antibody blocking of BSAT1 during the prenatal period is followed by cognitive impairments, which are probably related to thyroxin deficiency in the nervous tissue.
Title: Effects of prenatal exposure to antibodies against brain-specific anion transporter on cognitive functions in rats.

In the brain, BSAT1 is localized predominantly in astrocytes, but not in endothelial cells.
Title: Organ, cellular, and subcellular localization of brain-specific anion transporter BSAT1.

The following Slco1c1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Slco1c1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa09589	NM_053441.1 Latest version!	Rattus norvegicus solute carrier organic anion transporter family, member 1c1 (Slco1c1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Slco1c1 ( NM_053441.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_445893.1 Rattus norvegicus solute carrier organic anion transporter family, member 1c1 (Slco1c1), mRNA.

Price & Availability↑

CloneID	ORa09589
Clone ID Related Accession (Same CDS sequence)	NM_053441.1
Accession Version	NM_053441.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2151bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-26
Organism	Rattus norvegicus(Norway rat)
Product	solute carrier organic anion transporter family member 1C1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF306546.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF306546.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGACACTT CATCCAAAGA AAATGCCCAT TTGTTCCACA AAAATTCAGC GCAACCTGCC 
GGAGGGCCAT CTTTTAAAGC GGGATATCCG TCCACAGAGG AAGCGCGGCC ATGCTGTGGA 
AAACTCAAGG TGTTCTTAGG TGCCCTGTCT TTTGTTTACT TTGCCAAAGC ATTGACAGAA 
GGCTACCTGA AGAGCACTAT TACTCAGATA GAGAGAAGGT TTGATATCCC TTCCTCTCTG 
GTGGGAATAA TTGATGGTAG TTTCGAAATT GGGAATCTCC TGGTCATAAC ATTCGTTAGC 
TACTTTGGTG CCAAACTTCA CAGGCCAAAA ATAATTGGAG CAGGATGCCT GGTCATGGGC 
TTTGGAACTA TGCTCATCGC AGTTCCCCAG TTCTTCATGG AGAAGTACAG CTATGAGAAA 
TATGAGAGGT ATTCTCCCTC CTCCAACCTC ACTCCCAACA TCTCTCCGTG CTACCTAGAG 
TCCAGCAGTC CATCACCACG CTCAATCGTG GGGAAATCAC AAAACAAGAT AAACGATGAG 
TGTGAAGTGG ATACCAGTTC CTCCATGTGG GTTTATGTCT TCCTGGGAAA CCTTCTCCGA 
GGATTAGGGG AAACTCCTAT CCAACCCCTG GGCATCGCCT ACCTGGATGA TTTCGCCAGT 
GAAGACAATG CTGCCTTCTA CATCGGGTGT GTGCAGACAG TGGCAATTAT AGGGCCCATT 
TTCGGCTTCC TCTTGGGTTC ATTATGTGCC AAACTCTATG TTGATATTGG CTTTGTGAAT 
CTAGACCACA TAACTATCAC CCCAAAGGAT CCCCAGTGGG TCGGGGCCTG GTGGCTTGGT 
TACCTAATAG CAGGGTTCCT AAGTCTTCTT GCAGCCGTGC CTTTCTGGTG CTTACCCAAG 
ACTCTACCAA GATCCCAAAG TAGAGAGGAC TCCGGCTCCT CCTCTGAGAA ATCCAAGTTC 
ATTACAGATG ACCCTGTTAA CTACCAAATG GCCCCCAGAG AAGAAAGCAT GAAAATCATG 
GAAATGGCGA GGGATTTTCT TCCATCACTG AAGAGTCTTT TTAGAAATCC AGTATACATC 
TTATACTTGT GTGCAAGCAC TGTTCAGTTC AATTCTCTAT TCGGCATGGT CACATATAAA 
CCAAAGTACA TTGAGCAGCA GTATGGGCAG TCTTCCTCCA AAGCCAACTT TGTCATTGGT 
CTCATCAATA TTCCTGCAGT GGCCCTTGGA ATATTCTCTG GGGGAATAGT TATGAAAAAA 
TTCAGGCTGG GTATTTGTGA AGCTACAAAA CTCTACTTGG GATCATCTGT CTTTGGCTAC 
CTCCTCTTCC TCTCTCTGTT TGCACTGGGA TGTGAAAATT CCAGTGTGGC CGGACTAACT 
GTCTCCTACC AAGGAACCAA ACCTGTCTCT TATCATGAAC GAGCTCTCTT TTCAGATTGC 
AACTCAAGAT GCAAATGTTC AGACTCAAAA TGGGAGCCCA TGTGTGGGGA CAATGGGATT 
ACCTATGCGT CGGCTTGTCT TGCTGGCTGT CAATCCTCCA GCCGGAGTGG AAAGAACATT 
ATATTTTCTA ACTGCACTTG TGTGGGATTT GCTGCCCCTA AATCAGGAAA CTGGTCAGGC 
ATGATGGGCA GGTGTCAGAA AGATAATGGA TGTTCCCAAA TGTTTCTGTA TTTCCTTGTG 
ATTTCAGTCA TCACATCATA TACATTATCT CTAGGTGGCA TACCTGGATA TATATTACTC 
TTGAGGTGCA TTCAACCACA ACTTAAGTCT TTTGCTCTGG GCATCTACAC CTTAGCAGTA 
AGAGTTCTTG CAGGAATCCC AGCCCCCGTG TACTTTGGTG TTTTAATCGA CACTTCGTGC 
CTCAAGTGGG GATTTAAGAA ATGTGGAAGC AGAGGCTCCT GCAGACTGTA CGACTCTCAT 
GCTTTCAGAC ATATATACCT GGGACTAACC ACGCTCTTGG GCACGGTGTC TGTCTTCCTA 
AGCACGGCTG TGCTTTTGGT TTTAAAGAAA AAATACGTCT CAAAACGCAG CAGCTTCATA 
ACCGCAAGAG AAAAAATAGT GATGTCCTCA AGCGTCAAAA AGGAGACGTG TGCCGCAAGG 
GATCATGGGT TGCAGCCCAA GTACTGGCCA GGCAAGGAGA CCCGACTTTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_445893.1
CDS	375..2525
Translation	MDTSSKENAHLFHKNSAQPAGGPSFKAGYPSTEEARPCCGKLKVFLGALSFVYFAKALTEGYLKSTITQIERRFDIPSSLVGIIDGSFEIGNLLVITFVSYFGAKLHRPKIIGAGCLVMGFGTMLIAVPQFFMEKYSYEKYERYSPSSNLTPNISPCYLESSSPSPRSIVGKSQNKINDECEVDTSSSMWVYVFLGNLLRGLGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGFLSLLAAVPFWCLPKTLPRSQSREDSGSSSEKSKFITDDPVNYQMAPREESMKIMEMARDFLPSLKSLFRNPVYILYLCASTVQFNSLFGMVTYKPKYIEQQYGQSSSKANFVIGLINIPAVALGIFSGGIVMKKFRLGICEATKLYLGSSVFGYLLFLSLFALGCENSSVAGLTVSYQGTKPVSYHERALFSDCNSRCKCSDSKWEPMCGDNGITYASACLAGCQSSSRSGKNIIFSNCTCVGFAAPKSGNWSGMMGRCQKDNGCSQMFLYFLVISVITSYTLSLGGIPGYILLLRCIQPQLKSFALGIYTLAVRVLAGIPAPVYFGVLIDTSCLKWGFKKCGSRGSCRLYDSHAFRHIYLGLTTLLGTVSVFLSTAVLLVLKKKYVSKRSSFITAREKIVMSSSVKKETCAARDHGLQPKYWPGKETRL

Target ORF information:

RefSeq Version	NM_053441.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier organic anion transporter family, member 1c1 (Slco1c1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_053441.1

ORF Insert Sequence:

ATGGACACTT CATCCAAAGA AAATGCCCAT TTGTTCCACA AAAATTCAGC GCAACCTGCC 
GGAGGGCCAT CTTTTAAAGC GGGATATCCG TCCACAGAGG AAGCGCGGCC ATGCTGTGGA 
AAACTCAAGG TGTTCTTAGG TGCCCTGTCT TTTGTTTACT TTGCCAAAGC ATTGACAGAA 
GGCTACCTGA AGAGCACTAT TACTCAGATA GAGAGAAGGT TTGATATCCC TTCCTCTCTG 
GTGGGAATAA TTGATGGTAG TTTCGAAATT GGGAATCTCC TGGTCATAAC ATTCGTTAGC 
TACTTTGGTG CCAAACTTCA CAGGCCAAAA ATAATTGGAG CAGGATGCCT GGTCATGGGC 
TTTGGAACTA TGCTCATCGC AGTTCCCCAG TTCTTCATGG AGAAGTACAG CTATGAGAAA 
TATGAGAGGT ATTCTCCCTC CTCCAACCTC ACTCCCAACA TCTCTCCGTG CTACCTAGAG 
TCCAGCAGTC CATCACCACG CTCAATCGTG GGGAAATCAC AAAACAAGAT AAACGATGAG 
TGTGAAGTGG ATACCAGTTC CTCCATGTGG GTTTATGTCT TCCTGGGAAA CCTTCTCCGA 
GGATTAGGGG AAACTCCTAT CCAACCCCTG GGCATCGCCT ACCTGGATGA TTTCGCCAGT 
GAAGACAATG CTGCCTTCTA CATCGGGTGT GTGCAGACAG TGGCAATTAT AGGGCCCATT 
TTCGGCTTCC TCTTGGGTTC ATTATGTGCC AAACTCTATG TTGATATTGG CTTTGTGAAT 
CTAGACCACA TAACTATCAC CCCAAAGGAT CCCCAGTGGG TCGGGGCCTG GTGGCTTGGT 
TACCTAATAG CAGGGTTCCT AAGTCTTCTT GCAGCCGTGC CTTTCTGGTG CTTACCCAAG 
ACTCTACCAA GATCCCAAAG TAGAGAGGAC TCCGGCTCCT CCTCTGAGAA ATCCAAGTTC 
ATTACAGATG ACCCTGTTAA CTACCAAATG GCCCCCAGAG AAGAAAGCAT GAAAATCATG 
GAAATGGCGA GGGATTTTCT TCCATCACTG AAGAGTCTTT TTAGAAATCC AGTATACATC 
TTATACTTGT GTGCAAGCAC TGTTCAGTTC AATTCTCTAT TCGGCATGGT CACATATAAA 
CCAAAGTACA TTGAGCAGCA GTATGGGCAG TCTTCCTCCA AAGCCAACTT TGTCATTGGT 
CTCATCAATA TTCCTGCAGT GGCCCTTGGA ATATTCTCTG GGGGAATAGT TATGAAAAAA 
TTCAGGCTGG GTATTTGTGA AGCTACAAAA CTCTACTTGG GATCATCTGT CTTTGGCTAC 
CTCCTCTTCC TCTCTCTGTT TGCACTGGGA TGTGAAAATT CCAGTGTGGC CGGACTAACT 
GTCTCCTACC AAGGAACCAA ACCTGTCTCT TATCATGAAC GAGCTCTCTT TTCAGATTGC 
AACTCAAGAT GCAAATGTTC AGACTCAAAA TGGGAGCCCA TGTGTGGGGA CAATGGGATT 
ACCTATGCGT CGGCTTGTCT TGCTGGCTGT CAATCCTCCA GCCGGAGTGG AAAGAACATT 
ATATTTTCTA ACTGCACTTG TGTGGGATTT GCTGCCCCTA AATCAGGAAA CTGGTCAGGC 
ATGATGGGCA GGTGTCAGAA AGATAATGGA TGTTCCCAAA TGTTTCTGTA TTTCCTTGTG 
ATTTCAGTCA TCACATCATA TACATTATCT CTAGGTGGCA TACCTGGATA TATATTACTC 
TTGAGGTGCA TTCAACCACA ACTTAAGTCT TTTGCTCTGG GCATCTACAC CTTAGCAGTA 
AGAGTTCTTG CAGGAATCCC AGCCCCCGTG TACTTTGGTG TTTTAATCGA CACTTCGTGC 
CTCAAGTGGG GATTTAAGAA ATGTGGAAGC AGAGGCTCCT GCAGACTGTA CGACTCTCAT 
GCTTTCAGAC ATATATACCT GGGACTAACC ACGCTCTTGG GCACGGTGTC TGTCTTCCTA 
AGCACGGCTG TGCTTTTGGT TTTAAAGAAA AAATACGTCT CAAAACGCAG CAGCTTCATA 
ACCGCAAGAG AAAAAATAGT GATGTCCTCA AGCGTCAAAA AGGAGACGTG TGCCGCAAGG 
GATCATGGGT TGCAGCCCAA GTACTGGCCA GGCAAGGAGA CCCGACTTTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Prenatal exposure to brain-specific anion transporter-1-specific monoclonal antibodies impairs cognitive function in post-natal life.
Neuropeptides65100-105(2017 Oct)
Zubkov EA,Zorkina YA,Gurina OI,Melnikov PA,Morozova AY,Chekhonin VP

Antidepressant behavior in thyroidectomized Wistar rats is induced by hippocampal hypothyroidism.
Physiology & behavior157158-64(2016 Apr)
da Concei??o RR,Laureano-Melo R,Oliveira KC,de Carvalho Melo MC,Kasamatsu TS,de Barros Maciel RM,de Souza JS,Giannocco G

Parallel regulation of thyroid hormone transporters OATP1c1 and MCT8 during and after endotoxemia at the blood-brain barrier of male rodents.
Endocrinology156(4)1552-64(2015 Apr)
Wittmann G,Szabon J,Moh?csik P,Nouriel SS,Gereben B,Fekete C,Lechan RM

Expression of organic anion transporting polypeptide 1c1 and monocarboxylate transporter 8 in the rat placental barrier and the compensatory response to thyroid dysfunction.
PloS one9(4)e96047(2014)
Sun YN,Liu YJ,Zhang L,Ye Y,Lin LX,Li YM,Yan YQ,Chen ZP

Organ, cellular, and subcellular localization of brain-specific anion transporter BSAT1.
Bulletin of experimental biology and medicine155(4)491-7(2013 Aug)
Baklaushev VP,Kardashova KSh,Gurina OI,Yusubaliyeva GM,Zorkina YA,Chekhonin VP

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Slco1c1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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