Meox1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Meox1
Entrez Gene ID	363684
Full Name	mesenchyme homeobox 1
General protein information	Preferred Names mesenchyme homeobox 1 Names homeobox protein MOX-1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q32.1

mRNA and Protein(s)

mRNA	Protein	Name
XM_008768090.2	XP_008766312.1	homeobox protein MOX-1 isoform X1
NM_001108837.1	NP_001102307.1	homeobox protein MOX-1

Pathways from BioSystems

Homologies

Bos taurus (cattle)	MEOX1	NP_001030453.2
Rattus norvegicus (Norway rat)	Meox1	NP_001102307.1
Danio rerio (zebrafish)	meox1	NP_001002450.2
Homo sapiens (human)	MEOX1	NP_004518.1
Pan troglodytes (chimpanzee)	MEOX1	NP_001129096.2
	MEOX1	XP_001113649.1
Mus musculus (house mouse)	Meox1	NP_034921.1
Canis lupus familiaris (dog)	MEOX1	XP_005624477.1
Gallus gallus (chicken)	MEOX1	NP_990096.1

Gene Ontology
Bibliography

Related articles in PubMed

Mesoderm/mesenchyme homeobox gene l promotes vascular smooth muscle cell phenotypic modulation and vascular remodeling.
Wu B, Zhang L, Zhu YH, Zhang YE, Zheng F, Yang JY, Guo LY, Li XY, Wang L, Tang JM, Chen SY, Wang JN
International journal of cardiology25182-89(2018 Jan)

Mechanisms of MEOX1 and MEOX2 regulation of the cyclin dependent kinase inhibitors p21 and p16 in vascular endothelial cells.
Douville JM, Cheung DY, Herbert KL, Moffatt T, Wigle JT
PloS one6(12)e29099(2011)

Lack of the mesodermal homeodomain protein MEOX1 disrupts sclerotome polarity and leads to a remodeling of the cranio-cervical joints of the axial skeleton.
Skuntz S, Mankoo B, Nguyen MT, Hustert E, Nakayama A, Tournier-Lasserve E, Wright CV, Pachnis V, Bharti K, Arnheiter H
Developmental biology332(2)383-95(2009 Aug)

The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors.
Wissm?ller S, Kosian T, Wolf M, Finzsch M, Wegner M
Nucleic acids research34(6)1735-44(2006)

Meox homeodomain proteins are required for Bapx1 expression in the sclerotome and activate its transcription by direct binding to its promoter.
Rodrigo I, Bovolenta P, Mankoo BS, Imai K
Molecular and cellular biology24(7)2757-66(2004 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Meox1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Meox1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa08465	NM_001108837.1 Latest version!	Rattus norvegicus mesenchyme homeobox 1 (Meox1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
ORa48611	XM_008768090.2 Latest version!	Rattus norvegicus mesenchyme homeobox 1 (Meox1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Meox1 ( NM_001108837.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001102307.1 Rattus norvegicus mesenchyme homeobox 1 (Meox1), mRNA.

Price & Availability↑

CloneID	ORa08465
Clone ID Related Accession (Same CDS sequence)	NM_001108837.1
Accession Version	NM_001108837.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 762bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-07-21
Organism	Rattus norvegicus(Norway rat)
Product	homeobox protein MOX-1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473948.1. On or before Oct 4, 2007 this sequence version replaced XM_343970.3, XM_001081499.1. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN01906347, SAMN01906348 [ECO:0000348] ##Evidence-Data-END##

ATGGATCCGG TGGTCAACAG CTGCGTGAGG AACCCCCAGC CCCCAGCTCC CGTCTGGGGC 
TGCCTTCGAA ACCCCCACTC GGAAGGCAGC AGCGCCTCAG GGCTGCCCCA TTACCCACCA 
ACCCCGTTTT CCTTCCACCA AAAGTCCGAT TTCCCAGCGA CAGCAGCATA CCCCGACTTC 
TCTACTTCCT GCCTGGCAGC CACCCCACAC AGCCTGCCCC GCGCTGAGCG AATCTTCAAT 
GAGCAGCATC CTGCCTTCCC ACAGACCCCT GACTGGCATT TCCCCATCTC TGAAGCGGGG 
CAAAGGCTCA ACCTAGGCCC AGCTGGGAGC GCCAGAGAGA TGGGGGCTGG CAGCCCCGGC 
CTGGTGGACG GCACAGGAGG ATTGGGTGAG GACTGCATGG TGCTTGGGAC CATCGCCCAT 
GAGACGGAGA AGAAATTATC CAGAAGGAAA AAGGAGAGGT CAGACAACCC AGAGAATGGA 
GGAGGAAAGC CAGAAGGCAG CAGCAAGGCC CGGAAGGAAA GGACAGCTTT CACCAAGGAG 
CAGCTACGGG AGCTAGAGGC TGAGTTCGCC CACCATAACT ACCTGACCAG GCTCCGTAGA 
TACGAGATTG CAGTCAACCT GGACCTTTCA GAGCGGCAGG TCAAAGTGTG GTTCCAGAAC 
CGGAGAATGA AGTGGAAGCG TGTGAAGGGG GGTCAGCCCG TGTCCCCACA GGAGCAGGAC 
CCAGAGGATG GAGACTCTGC AGCTTCTCCG AGTTCAGAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001102307.1
CDS	1..762
Translation	MDPVVNSCVRNPQPPAPVWGCLRNPHSEGSSASGLPHYPPTPFSFHQKSDFPATAAYPDFSTSCLAATPHSLPRAERIFNEQHPAFPQTPDWHFPISEAGQRLNLGPAGSAREMGAGSPGLVDGTGGLGEDCMVLGTIAHETEKKLSRRKKERSDNPENGGGKPEGSSKARKERTAFTKEQLRELEAEFAHHNYLTRLRRYEIAVNLDLSERQVKVWFQNRRMKWKRVKGGQPVSPQEQDPEDGDSAASPSSE

Target ORF information:

RefSeq Version	NM_001108837.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus mesenchyme homeobox 1 (Meox1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001108837.1

ORF Insert Sequence:

ATGGATCCGG TGGTCAACAG CTGCGTGAGG AACCCCCAGC CCCCAGCTCC CGTCTGGGGC 
TGCCTTCGAA ACCCCCACTC GGAAGGCAGC AGCGCCTCAG GGCTGCCCCA TTACCCACCA 
ACCCCGTTTT CCTTCCACCA AAAGTCCGAT TTCCCAGCGA CAGCAGCATA CCCCGACTTC 
TCTACTTCCT GCCTGGCAGC CACCCCACAC AGCCTGCCCC GCGCTGAGCG AATCTTCAAT 
GAGCAGCATC CTGCCTTCCC ACAGACCCCT GACTGGCATT TCCCCATCTC TGAAGCGGGG 
CAAAGGCTCA ACCTAGGCCC AGCTGGGAGC GCCAGAGAGA TGGGGGCTGG CAGCCCCGGC 
CTGGTGGACG GCACAGGAGG ATTGGGTGAG GACTGCATGG TGCTTGGGAC CATCGCCCAT 
GAGACGGAGA AGAAATTATC CAGAAGGAAA AAGGAGAGGT CAGACAACCC AGAGAATGGA 
GGAGGAAAGC CAGAAGGCAG CAGCAAGGCC CGGAAGGAAA GGACAGCTTT CACCAAGGAG 
CAGCTACGGG AGCTAGAGGC TGAGTTCGCC CACCATAACT ACCTGACCAG GCTCCGTAGA 
TACGAGATTG CAGTCAACCT GGACCTTTCA GAGCGGCAGG TCAAAGTGTG GTTCCAGAAC 
CGGAGAATGA AGTGGAAGCG TGTGAAGGGG GGTCAGCCCG TGTCCCCACA GGAGCAGGAC 
CCAGAGGATG GAGACTCTGC AGCTTCTCCG AGTTCAGAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Meox1 ( XM_008768090.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008766312.1 Rattus norvegicus mesenchyme homeobox 1 (Meox1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa48611
Clone ID Related Accession (Same CDS sequence)	XM_008768090.2
Accession Version	XM_008768090.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 987bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	homeobox protein MOX-1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008768090.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATCCGG TGGTCAACAG CTGCGTGAGG AACCCCCAGC CCCCAGCTCC CGTCTGGGGC 
TGCCTTCGAA ACCCCCACTC GGAAGGCAGC AGCGCCTCAG GGCTGCCCCA TTACCCACCA 
ACCCCGTTTT CCTTCCACCA AAAGTCCGAT TTCCCAGCGA CAGCAGCATA CCCCGACTTC 
TCTACTTCCT GCCTGGCAGC CACCCCACAC AGCCTGCCCC GCGCTGAGCG AATCTTCAAT 
GAGCAGCATC CTGCCTTCCC ACAGACCCCT GACTGGCATT TCCCCATCTC TGAAGCGGGG 
CAAAGGCTCA ACCTAGGCCC AGCTGGGAGC GCCAGAGAGA TGGGGGCTGG CAGCCCCGGC 
CTGGTGGACG GCACAGGAGG ATTGGGTGAG GACTGCATGG TGCTTGGGAC CATCGCCCAT 
GAGACGGAGA AGAAATTATC CAGAAGGAAA AAGGAGAGGT CAGGTCAAAG TGTGGTTCCA 
GAACCGGAGA ATGAAGTGGA AGCGTGTGAA GGGGGGTCAG CCCGTGTCCC CACAGGAGCA 
GGACCCAGAG GATGGAGACT CTGCAGCTTC TCCGAGTTCA GAGTGAGATG CTCCAAAGAC 
CAAAACCAAG AAAGACTGAA CGAACGCCCT TTCCAACTCC CACCACCCAC TCCCACCCTC 
ACATCTTCTG GACCCACCCA GGCAGCCTGC GCACACTCGT ACGTAGATGT GAAGTTGCCC 
AGTGTGGGAG CCTTGAATTT CCCAGAAGGT TTAGCCCAGC ATCGCCCCAG TCTCAGCAGC 
CCCTTCCCCA GGGCTTCAAT TTTCCACACT CTCTTGAACT CCACAGGACC CAGCGGACTG 
GGAAACTCTA GAAACAGAAC CTGGGACACT CTTTTCTGGG TCTCTTGGCT GCTACCCACA 
CCTACCATCC CCCTCTTACA TCAAGTCTCC TCTGGGTCTG GCCCCATATG GCCTGTGCAG 
AATCCATTCC TTGGTACCAG CTGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008766312.1
CDS	519..1505
Translation	MDPVVNSCVRNPQPPAPVWGCLRNPHSEGSSASGLPHYPPTPFSFHQKSDFPATAAYPDFSTSCLAATPHSLPRAERIFNEQHPAFPQTPDWHFPISEAGQRLNLGPAGSAREMGAGSPGLVDGTGGLGEDCMVLGTIAHETEKKLSRRKKERSGQSVVPEPENEVEACEGGSARVPTGAGPRGWRLCSFSEFRVRCSKDQNQERLNERPFQLPPPTPTLTSSGPTQAACAHSYVDVKLPSVGALNFPEGLAQHRPSLSSPFPRASIFHTLLNSTGPSGLGNSRNRTWDTLFWVSWLLPTPTIPLLHQVSSGSGPIWPVQNPFLGTSW

Target ORF information:

RefSeq Version	XM_008768090.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus mesenchyme homeobox 1 (Meox1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008768090.2

ORF Insert Sequence:

ATGGATCCGG TGGTCAACAG CTGCGTGAGG AACCCCCAGC CCCCAGCTCC CGTCTGGGGC 
TGCCTTCGAA ACCCCCACTC GGAAGGCAGC AGCGCCTCAG GGCTGCCCCA TTACCCACCA 
ACCCCGTTTT CCTTCCACCA AAAGTCCGAT TTCCCAGCGA CAGCAGCATA CCCCGACTTC 
TCTACTTCCT GCCTGGCAGC CACCCCACAC AGCCTGCCCC GCGCTGAGCG AATCTTCAAT 
GAGCAGCATC CTGCCTTCCC ACAGACCCCT GACTGGCATT TCCCCATCTC TGAAGCGGGG 
CAAAGGCTCA ACCTAGGCCC AGCTGGGAGC GCCAGAGAGA TGGGGGCTGG CAGCCCCGGC 
CTGGTGGACG GCACAGGAGG ATTGGGTGAG GACTGCATGG TGCTTGGGAC CATCGCCCAT 
GAGACGGAGA AGAAATTATC CAGAAGGAAA AAGGAGAGGT CAGGTCAAAG TGTGGTTCCA 
GAACCGGAGA ATGAAGTGGA AGCGTGTGAA GGGGGGTCAG CCCGTGTCCC CACAGGAGCA 
GGACCCAGAG GATGGAGACT CTGCAGCTTC TCCGAGTTCA GAGTGAGATG CTCCAAAGAC 
CAAAACCAAG AAAGACTGAA CGAACGCCCT TTCCAACTCC CACCACCCAC TCCCACCCTC 
ACATCTTCTG GACCCACCCA GGCAGCCTGC GCACACTCGT ACGTAGATGT GAAGTTGCCC 
AGTGTGGGAG CCTTGAATTT CCCAGAAGGT TTAGCCCAGC ATCGCCCCAG TCTCAGCAGC 
CCCTTCCCCA GGGCTTCAAT TTTCCACACT CTCTTGAACT CCACAGGACC CAGCGGACTG 
GGAAACTCTA GAAACAGAAC CTGGGACACT CTTTTCTGGG TCTCTTGGCT GCTACCCACA 
CCTACCATCC CCCTCTTACA TCAAGTCTCC TCTGGGTCTG GCCCCATATG GCCTGTGCAG 
AATCCATTCC TTGGTACCAG CTGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Mesoderm/mesenchyme homeobox gene l promotes vascular smooth muscle cell phenotypic modulation and vascular remodeling.
International journal of cardiology25182-89(2018 Jan)
Wu B,Zhang L,Zhu YH,Zhang YE,Zheng F,Yang JY,Guo LY,Li XY,Wang L,Tang JM,Chen SY,Wang JN

Mechanisms of MEOX1 and MEOX2 regulation of the cyclin dependent kinase inhibitors p21 and p16 in vascular endothelial cells.
PloS one6(12)e29099(2011)
Douville JM,Cheung DY,Herbert KL,Moffatt T,Wigle JT

Lack of the mesodermal homeodomain protein MEOX1 disrupts sclerotome polarity and leads to a remodeling of the cranio-cervical joints of the axial skeleton.
Developmental biology332(2)383-95(2009 Aug)
Skuntz S,Mankoo B,Nguyen MT,Hustert E,Nakayama A,Tournier-Lasserve E,Wright CV,Pachnis V,Bharti K,Arnheiter H

The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors.
Nucleic acids research34(6)1735-44(2006)
Wissm?ller S,Kosian T,Wolf M,Finzsch M,Wegner M

Meox homeodomain proteins are required for Bapx1 expression in the sclerotome and activate its transcription by direct binding to its promoter.
Molecular and cellular biology24(7)2757-66(2004 Apr)
Rodrigo I,Bovolenta P,Mankoo BS,Imai K

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Meox1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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