Arhgef6 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Arhgef6
Entrez Gene ID	363509
Full Name	Rac/Cdc42 guanine nucleotide exchange factor 6
General protein information	Preferred Names Rac/Cdc42 guanine nucleotide exchange factor 6 Names rho guanine nucleotide exchange factor 6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: X Map Location: Xq37

mRNA and Protein(s)

mRNA	Protein	Name
XM_008773652.2	XP_008771874.1	rho guanine nucleotide exchange factor 6 isoform X2
XM_008773651.2	XP_008771873.1	rho guanine nucleotide exchange factor 6 isoform X1
XM_017602114.1	XP_017457603.1	rho guanine nucleotide exchange factor 6 isoform X4
XM_008773654.2	XP_008771876.1	rho guanine nucleotide exchange factor 6 isoform X4
NM_001005565.1	NP_001005565.1	rho guanine nucleotide exchange factor 6
XM_008773653.2	XP_008771875.1	rho guanine nucleotide exchange factor 6 isoform X3

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	ARHGEF6	XP_852793.2
Rattus norvegicus (Norway rat)	Arhgef6	NP_001005565.1
Xenopus tropicalis (tropical clawed frog)	arhgef6	XP_002932671.2
Gallus gallus (chicken)	ARHGEF6	NP_001006432.1
Danio rerio (zebrafish)	LOC558288	XP_686581.4
Homo sapiens (human)	ARHGEF6	NP_004831.1
Mus musculus (house mouse)	Arhgef6	NP_690014.2
Pan troglodytes (chimpanzee)	ARHGEF6	XP_003954148.1
Bos taurus (cattle)	ARHGEF6	NP_001179929.1
	ARHGEF6	XP_001083544.1

Gene Ontology
Bibliography

Related articles in PubMed

c-Cbl regulates ?Pix-mediated cell migration and invasion.
Seong MW, Park JH, Yoo HM, Yang SW, Oh KH, Ka SH, Park DE, Lee ST, Chung CH
Biochemical and biophysical research communications455(3-4)153-8(2014 Dec)

The lymphoid lineage-specific actin-uncapping protein Rltpr is essential for costimulation via CD28 and the development of regulatory T cells.
Liang Y, Cucchetti M, Roncagalli R, Yokosuka T, Malzac A, Bertosio E, Imbert J, Nijman IJ, Suchanek M, Saito T, W?lfing C, Malissen B, Malissen M
Nature immunology14(8)858-66(2013 Aug)

Biochemical and functional characterisation of ?PIX, a specific regulator of axonal and dendritic branching in hippocampal neurons.
Totaro A, Tavano S, Filosa G, G?rtner A, Pennucci R, Santambrogio P, Bachi A, Dotti CG, de Curtis I
Biology of the cell104(9)533-52(2012 Sep)

betaPIX-activated Rac1 stimulates the activation of phospholipase D, which is associated with exocytosis in neuroendocrine cells.
Momboisse F, Lonchamp E, Calco V, Ceridono M, Vitale N, Bader MF, Gasman S
Journal of cell science122(Pt 6)798-806(2009 Mar)

Affixin activates Rac1 via betaPIX in C2C12 myoblast.
Matsuda C, Kameyama K, Suzuki A, Mishima W, Yamaji S, Okamoto H, Nishino I, Hayashi YK
FEBS letters582(8)1189-96(2008 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

c-Cbl negatively regulates alphaPix-mediated cell migration and invasion; the lack of c-Cbl in C6 and A172 glioma cells is responsible for their malignant behavior
Title: c-Cbl regulates ?Pix-mediated cell migration and invasion.

alphaPIX and GIT2 are required for neuronal differentiation.
Title: Biochemical and functional characterisation of ?PIX, a specific regulator of axonal and dendritic branching in hippocampal neurons.

betaPix is identified as the guanine nucleotide-exchange factor integrating Rac1 activation to PLD1 and the exocytotic process.
Title: betaPIX-activated Rac1 stimulates the activation of phospholipase D, which is associated with exocytosis in neuroendocrine cells.

The following Arhgef6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Arhgef6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa48594	XM_008773654.2 Latest version!	Rattus norvegicus Rac/Cdc42 guanine nucleotide exchange factor 6 (Arhgef6), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa48594	XM_017602114.1 Latest version!	Rattus norvegicus Rac/Cdc42 guanine nucleotide exchange factor 6 (Arhgef6), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa42454	NM_001005565.1 Latest version!	Rattus norvegicus Rac/Cdc42 guanine nucleotide exchange factor 6 (Arhgef6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
ORa48591	XM_008773651.2 Latest version!	Rattus norvegicus Rac/Cdc42 guanine nucleotide exchange factor 6 (Arhgef6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
ORa48592	XM_008773652.2 Latest version!	Rattus norvegicus Rac/Cdc42 guanine nucleotide exchange factor 6 (Arhgef6), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
ORa48593	XM_008773653.2 Latest version!	Rattus norvegicus Rac/Cdc42 guanine nucleotide exchange factor 6 (Arhgef6), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Arhgef6 ( XM_017602114.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017457603.1 Rattus norvegicus Rac/Cdc42 guanine nucleotide exchange factor 6 (Arhgef6), transcript variant X4, mRNA.

Price & Availability↑

CloneID	ORa48594
Clone ID Related Accession (Same CDS sequence)	XM_017602114.1 , XM_008773654.2
Accession Version	XM_017602114.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1857bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	rho guanine nucleotide exchange factor 6 isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005120.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACGGAAA ATGGAAGTCA CCAGTTGATA GTAAAGGCAA GATTCAACTT CAAGCAGACC 
AATGAAGATG AATTGTCAGT GTGTAAAGGG GACATCATTT ATGTCACTCG AGTTGAAGAA 
GGAGGCTGGT GGGAAGGCAC ATTAAATGGG AGAACCGGAT GGTTCCCTAG TAATTATGTT 
CGAGAAATTA AACCCAGTGA GAGACCTCTG TCCCCTAAGG CTGTCAAAGG ATTTGACACT 
GCTCCACTTA CCAAGAATTA CTACACTGTG GTGTTACAGA ACATCTTGGA CACTGAAAAA 
GAATATGCCA AAGAACTTCA GTCTCTTCTT GTTACTTACC TAAGACCTTT GCAGTCTAAT 
AACAACCTGA GTACTGTGGA GTTTACATGC TTATTGGGAA ACTTTGAAGA AGTATGCACA 
TTTCAACAGA CACTCTGCCA AGCCCTGGAA GAATGCTCAA AGTCTCCAGA AAACCAGCAC 
AAAGTAGGAG GCTGCCTACT GAACCTCATG CCTCATTTTA AATCGATGTA CCTGGCTTAC 
TGTGCAAATC ATCCTTCAGC TGTCAACGTG CTCACCCAGC ATAGTGATGA TCTAGAACGA 
TTCATGGAAA ATCAAGGTGC ATCCAGCCCC GGTATCCTCA TTTTAACAAC AAGTCTCAGC 
AAACCATTCA TGCGACTGGA AAAGTATGTT ACTCTCTTGC AAGAACTGGA ACGGCATATG 
GAGGACACTC ATCCAGATCA TCAGGATATT CTGAAAGCTA TCATAGCATT CAAAAGCCTC 
ATGGGGCAGT GCCAAGATCT GAGAAAGAGA AAGCAGCTGG AATTGCAGAT CCTTTCGGAA 
CCTATTCAGG CATGGGAAGG AGATGATATT AAGACTTTGG GAAATGTGAT CTTTATGTCA 
CAAGTAGTGA TGCAGCATGG AGCCTGTGAG GAAAAAGAGG AACGATATTT TCTGCTCTTT 
TCAAGTGTCT TGATCATGTT GTCTGCAAGT CCGCGGATGA GTGGCTTTAT GTATCAGGGA 
AAGGTACCAA TAGCAGGGAT GGTCGTGACC AGATTGGATG AAATTGAAGG AAATGACTGT 
ACATTCGAAA TCACCGGTAG CACGGTAGAG AGAATTGTGG TCCACTGCAA CAATAACCAG 
GACTTCCAGG AGTGGATGGA GCAGCTGAAC AGACTGACCA AAGGACCAGC CTCCTGCAGT 
TCATTGTCTA AGACCTCCTC ATCATCATGT AGTACTCATT CTTCTTTTAG CTCTACCGGA 
CAGCCCCGAG GACCCTTGGA GCCTCCTCAA ATTATAAAAC CGTGGAGTTT AAGTTGCCTA 
CGACCTGCAC CTCCACTTAG ACCATCAGCA GCACTAGGTT ATAAAGAGAG GATGTCTTAT 
ATCTTAAAGG AATCTAGTAA GAGCCCCAAA ACGATGAAGA AGTTTCTTCA CAAAAGAAAG 
ACGGAGAGAA AGACATCCGA GGAAGAATAC GTGATTAGGA AAAGTACTGC TGCCCTGGAA 
GAGGATGCTC AGATTCTTAA GGTGATTGAA GCTTATTGCA CCAGCGCCAG TTTTCAACAA 
GGTACTCGTA AAGATTCAGT TCCACAAGTA CTCCTCCCCG AGGAAGAGAA ACTCATTATT 
GAAGAAACTA GAAGTAATGG GCAGACCATC ATTGAAGAGA AGAGCCTTGT TGATACTGTC 
TATGCCTTGA AGGATGAGGT CAAGGAATTG AAGCAGGAGA ATAAAAAAAT GAAGCAATGT 
CTGGAAGAAG AATTGAAGTC GAGGAAGGAC CTAGAAAAAC TGGTCCGGAA GCTGTTGAAG 
CAAACCGATG AATGCATTCG CGCTGAATCC AGCAGCAAGA CCTCGATTCT TCAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017457603.1
CDS	832..2688
Translation	MTENGSHQLIVKARFNFKQTNEDELSVCKGDIIYVTRVEEGGWWEGTLNGRTGWFPSNYVREIKPSERPLSPKAVKGFDTAPLTKNYYTVVLQNILDTEKEYAKELQSLLVTYLRPLQSNNNLSTVEFTCLLGNFEEVCTFQQTLCQALEECSKSPENQHKVGGCLLNLMPHFKSMYLAYCANHPSAVNVLTQHSDDLERFMENQGASSPGILILTTSLSKPFMRLEKYVTLLQELERHMEDTHPDHQDILKAIIAFKSLMGQCQDLRKRKQLELQILSEPIQAWEGDDIKTLGNVIFMSQVVMQHGACEEKEERYFLLFSSVLIMLSASPRMSGFMYQGKVPIAGMVVTRLDEIEGNDCTFEITGSTVERIVVHCNNNQDFQEWMEQLNRLTKGPASCSSLSKTSSSSCSTHSSFSSTGQPRGPLEPPQIIKPWSLSCLRPAPPLRPSAALGYKERMSYILKESSKSPKTMKKFLHKRKTERKTSEEEYVIRKSTAALEEDAQILKVIEAYCTSASFQQGTRKDSVPQVLLPEEEKLIIEETRSNGQTIIEEKSLVDTVYALKDEVKELKQENKKMKQCLEEELKSRKDLEKLVRKLLKQTDECIRAESSSKTSILQ

Target ORF information:

RefSeq Version	XM_017602114.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus Rac/Cdc42 guanine nucleotide exchange factor 6 (Arhgef6), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017602114.1

ORF Insert Sequence:

ATGACGGAAA ATGGAAGTCA CCAGTTGATA GTAAAGGCAA GATTCAACTT CAAGCAGACC 
AATGAAGATG AATTGTCAGT GTGTAAAGGG GACATCATTT ATGTCACTCG AGTTGAAGAA 
GGAGGCTGGT GGGAAGGCAC ATTAAATGGG AGAACCGGAT GGTTCCCTAG TAATTATGTT 
CGAGAAATTA AACCCAGTGA GAGACCTCTG TCCCCTAAGG CTGTCAAAGG ATTTGACACT 
GCTCCACTTA CCAAGAATTA CTACACTGTG GTGTTACAGA ACATCTTGGA CACTGAAAAA 
GAATATGCCA AAGAACTTCA GTCTCTTCTT GTTACTTACC TAAGACCTTT GCAGTCTAAT 
AACAACCTGA GTACTGTGGA GTTTACATGC TTATTGGGAA ACTTTGAAGA AGTATGCACA 
TTTCAACAGA CACTCTGCCA AGCCCTGGAA GAATGCTCAA AGTCTCCAGA AAACCAGCAC 
AAAGTAGGAG GCTGCCTACT GAACCTCATG CCTCATTTTA AATCGATGTA CCTGGCTTAC 
TGTGCAAATC ATCCTTCAGC TGTCAACGTG CTCACCCAGC ATAGTGATGA TCTAGAACGA 
TTCATGGAAA ATCAAGGTGC ATCCAGCCCC GGTATCCTCA TTTTAACAAC AAGTCTCAGC 
AAACCATTCA TGCGACTGGA AAAGTATGTT ACTCTCTTGC AAGAACTGGA ACGGCATATG 
GAGGACACTC ATCCAGATCA TCAGGATATT CTGAAAGCTA TCATAGCATT CAAAAGCCTC 
ATGGGGCAGT GCCAAGATCT GAGAAAGAGA AAGCAGCTGG AATTGCAGAT CCTTTCGGAA 
CCTATTCAGG CATGGGAAGG AGATGATATT AAGACTTTGG GAAATGTGAT CTTTATGTCA 
CAAGTAGTGA TGCAGCATGG AGCCTGTGAG GAAAAAGAGG AACGATATTT TCTGCTCTTT 
TCAAGTGTCT TGATCATGTT GTCTGCAAGT CCGCGGATGA GTGGCTTTAT GTATCAGGGA 
AAGGTACCAA TAGCAGGGAT GGTCGTGACC AGATTGGATG AAATTGAAGG AAATGACTGT 
ACATTCGAAA TCACCGGTAG CACGGTAGAG AGAATTGTGG TCCACTGCAA CAATAACCAG 
GACTTCCAGG AGTGGATGGA GCAGCTGAAC AGACTGACCA AAGGACCAGC CTCCTGCAGT 
TCATTGTCTA AGACCTCCTC ATCATCATGT AGTACTCATT CTTCTTTTAG CTCTACCGGA 
CAGCCCCGAG GACCCTTGGA GCCTCCTCAA ATTATAAAAC CGTGGAGTTT AAGTTGCCTA 
CGACCTGCAC CTCCACTTAG ACCATCAGCA GCACTAGGTT ATAAAGAGAG GATGTCTTAT 
ATCTTAAAGG AATCTAGTAA GAGCCCCAAA ACGATGAAGA AGTTTCTTCA CAAAAGAAAG 
ACGGAGAGAA AGACATCCGA GGAAGAATAC GTGATTAGGA AAAGTACTGC TGCCCTGGAA 
GAGGATGCTC AGATTCTTAA GGTGATTGAA GCTTATTGCA CCAGCGCCAG TTTTCAACAA 
GGTACTCGTA AAGATTCAGT TCCACAAGTA CTCCTCCCCG AGGAAGAGAA ACTCATTATT 
GAAGAAACTA GAAGTAATGG GCAGACCATC ATTGAAGAGA AGAGCCTTGT TGATACTGTC 
TATGCCTTGA AGGATGAGGT CAAGGAATTG AAGCAGGAGA ATAAAAAAAT GAAGCAATGT 
CTGGAAGAAG AATTGAAGTC GAGGAAGGAC CTAGAAAAAC TGGTCCGGAA GCTGTTGAAG 
CAAACCGATG AATGCATTCG CGCTGAATCC AGCAGCAAGA CCTCGATTCT TCAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Arhgef6 ( XM_008773654.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008771876.1 Rattus norvegicus Rac/Cdc42 guanine nucleotide exchange factor 6 (Arhgef6), transcript variant X5, mRNA.

Price & Availability↑

CloneID	ORa48594
Clone ID Related Accession (Same CDS sequence)	XM_017602114.1 , XM_008773654.2
Accession Version	XM_008773654.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1857bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	rho guanine nucleotide exchange factor 6 isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005120.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008773654.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACGGAAA ATGGAAGTCA CCAGTTGATA GTAAAGGCAA GATTCAACTT CAAGCAGACC 
AATGAAGATG AATTGTCAGT GTGTAAAGGG GACATCATTT ATGTCACTCG AGTTGAAGAA 
GGAGGCTGGT GGGAAGGCAC ATTAAATGGG AGAACCGGAT GGTTCCCTAG TAATTATGTT 
CGAGAAATTA AACCCAGTGA GAGACCTCTG TCCCCTAAGG CTGTCAAAGG ATTTGACACT 
GCTCCACTTA CCAAGAATTA CTACACTGTG GTGTTACAGA ACATCTTGGA CACTGAAAAA 
GAATATGCCA AAGAACTTCA GTCTCTTCTT GTTACTTACC TAAGACCTTT GCAGTCTAAT 
AACAACCTGA GTACTGTGGA GTTTACATGC TTATTGGGAA ACTTTGAAGA AGTATGCACA 
TTTCAACAGA CACTCTGCCA AGCCCTGGAA GAATGCTCAA AGTCTCCAGA AAACCAGCAC 
AAAGTAGGAG GCTGCCTACT GAACCTCATG CCTCATTTTA AATCGATGTA CCTGGCTTAC 
TGTGCAAATC ATCCTTCAGC TGTCAACGTG CTCACCCAGC ATAGTGATGA TCTAGAACGA 
TTCATGGAAA ATCAAGGTGC ATCCAGCCCC GGTATCCTCA TTTTAACAAC AAGTCTCAGC 
AAACCATTCA TGCGACTGGA AAAGTATGTT ACTCTCTTGC AAGAACTGGA ACGGCATATG 
GAGGACACTC ATCCAGATCA TCAGGATATT CTGAAAGCTA TCATAGCATT CAAAAGCCTC 
ATGGGGCAGT GCCAAGATCT GAGAAAGAGA AAGCAGCTGG AATTGCAGAT CCTTTCGGAA 
CCTATTCAGG CATGGGAAGG AGATGATATT AAGACTTTGG GAAATGTGAT CTTTATGTCA 
CAAGTAGTGA TGCAGCATGG AGCCTGTGAG GAAAAAGAGG AACGATATTT TCTGCTCTTT 
TCAAGTGTCT TGATCATGTT GTCTGCAAGT CCGCGGATGA GTGGCTTTAT GTATCAGGGA 
AAGGTACCAA TAGCAGGGAT GGTCGTGACC AGATTGGATG AAATTGAAGG AAATGACTGT 
ACATTCGAAA TCACCGGTAG CACGGTAGAG AGAATTGTGG TCCACTGCAA CAATAACCAG 
GACTTCCAGG AGTGGATGGA GCAGCTGAAC AGACTGACCA AAGGACCAGC CTCCTGCAGT 
TCATTGTCTA AGACCTCCTC ATCATCATGT AGTACTCATT CTTCTTTTAG CTCTACCGGA 
CAGCCCCGAG GACCCTTGGA GCCTCCTCAA ATTATAAAAC CGTGGAGTTT AAGTTGCCTA 
CGACCTGCAC CTCCACTTAG ACCATCAGCA GCACTAGGTT ATAAAGAGAG GATGTCTTAT 
ATCTTAAAGG AATCTAGTAA GAGCCCCAAA ACGATGAAGA AGTTTCTTCA CAAAAGAAAG 
ACGGAGAGAA AGACATCCGA GGAAGAATAC GTGATTAGGA AAAGTACTGC TGCCCTGGAA 
GAGGATGCTC AGATTCTTAA GGTGATTGAA GCTTATTGCA CCAGCGCCAG TTTTCAACAA 
GGTACTCGTA AAGATTCAGT TCCACAAGTA CTCCTCCCCG AGGAAGAGAA ACTCATTATT 
GAAGAAACTA GAAGTAATGG GCAGACCATC ATTGAAGAGA AGAGCCTTGT TGATACTGTC 
TATGCCTTGA AGGATGAGGT CAAGGAATTG AAGCAGGAGA ATAAAAAAAT GAAGCAATGT 
CTGGAAGAAG AATTGAAGTC GAGGAAGGAC CTAGAAAAAC TGGTCCGGAA GCTGTTGAAG 
CAAACCGATG AATGCATTCG CGCTGAATCC AGCAGCAAGA CCTCGATTCT TCAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008771876.1
CDS	291..2147
Translation	MTENGSHQLIVKARFNFKQTNEDELSVCKGDIIYVTRVEEGGWWEGTLNGRTGWFPSNYVREIKPSERPLSPKAVKGFDTAPLTKNYYTVVLQNILDTEKEYAKELQSLLVTYLRPLQSNNNLSTVEFTCLLGNFEEVCTFQQTLCQALEECSKSPENQHKVGGCLLNLMPHFKSMYLAYCANHPSAVNVLTQHSDDLERFMENQGASSPGILILTTSLSKPFMRLEKYVTLLQELERHMEDTHPDHQDILKAIIAFKSLMGQCQDLRKRKQLELQILSEPIQAWEGDDIKTLGNVIFMSQVVMQHGACEEKEERYFLLFSSVLIMLSASPRMSGFMYQGKVPIAGMVVTRLDEIEGNDCTFEITGSTVERIVVHCNNNQDFQEWMEQLNRLTKGPASCSSLSKTSSSSCSTHSSFSSTGQPRGPLEPPQIIKPWSLSCLRPAPPLRPSAALGYKERMSYILKESSKSPKTMKKFLHKRKTERKTSEEEYVIRKSTAALEEDAQILKVIEAYCTSASFQQGTRKDSVPQVLLPEEEKLIIEETRSNGQTIIEEKSLVDTVYALKDEVKELKQENKKMKQCLEEELKSRKDLEKLVRKLLKQTDECIRAESSSKTSILQ

Target ORF information:

RefSeq Version	XM_008773654.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus Rac/Cdc42 guanine nucleotide exchange factor 6 (Arhgef6), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008773654.2

ORF Insert Sequence:

ATGACGGAAA ATGGAAGTCA CCAGTTGATA GTAAAGGCAA GATTCAACTT CAAGCAGACC 
AATGAAGATG AATTGTCAGT GTGTAAAGGG GACATCATTT ATGTCACTCG AGTTGAAGAA 
GGAGGCTGGT GGGAAGGCAC ATTAAATGGG AGAACCGGAT GGTTCCCTAG TAATTATGTT 
CGAGAAATTA AACCCAGTGA GAGACCTCTG TCCCCTAAGG CTGTCAAAGG ATTTGACACT 
GCTCCACTTA CCAAGAATTA CTACACTGTG GTGTTACAGA ACATCTTGGA CACTGAAAAA 
GAATATGCCA AAGAACTTCA GTCTCTTCTT GTTACTTACC TAAGACCTTT GCAGTCTAAT 
AACAACCTGA GTACTGTGGA GTTTACATGC TTATTGGGAA ACTTTGAAGA AGTATGCACA 
TTTCAACAGA CACTCTGCCA AGCCCTGGAA GAATGCTCAA AGTCTCCAGA AAACCAGCAC 
AAAGTAGGAG GCTGCCTACT GAACCTCATG CCTCATTTTA AATCGATGTA CCTGGCTTAC 
TGTGCAAATC ATCCTTCAGC TGTCAACGTG CTCACCCAGC ATAGTGATGA TCTAGAACGA 
TTCATGGAAA ATCAAGGTGC ATCCAGCCCC GGTATCCTCA TTTTAACAAC AAGTCTCAGC 
AAACCATTCA TGCGACTGGA AAAGTATGTT ACTCTCTTGC AAGAACTGGA ACGGCATATG 
GAGGACACTC ATCCAGATCA TCAGGATATT CTGAAAGCTA TCATAGCATT CAAAAGCCTC 
ATGGGGCAGT GCCAAGATCT GAGAAAGAGA AAGCAGCTGG AATTGCAGAT CCTTTCGGAA 
CCTATTCAGG CATGGGAAGG AGATGATATT AAGACTTTGG GAAATGTGAT CTTTATGTCA 
CAAGTAGTGA TGCAGCATGG AGCCTGTGAG GAAAAAGAGG AACGATATTT TCTGCTCTTT 
TCAAGTGTCT TGATCATGTT GTCTGCAAGT CCGCGGATGA GTGGCTTTAT GTATCAGGGA 
AAGGTACCAA TAGCAGGGAT GGTCGTGACC AGATTGGATG AAATTGAAGG AAATGACTGT 
ACATTCGAAA TCACCGGTAG CACGGTAGAG AGAATTGTGG TCCACTGCAA CAATAACCAG 
GACTTCCAGG AGTGGATGGA GCAGCTGAAC AGACTGACCA AAGGACCAGC CTCCTGCAGT 
TCATTGTCTA AGACCTCCTC ATCATCATGT AGTACTCATT CTTCTTTTAG CTCTACCGGA 
CAGCCCCGAG GACCCTTGGA GCCTCCTCAA ATTATAAAAC CGTGGAGTTT AAGTTGCCTA 
CGACCTGCAC CTCCACTTAG ACCATCAGCA GCACTAGGTT ATAAAGAGAG GATGTCTTAT 
ATCTTAAAGG AATCTAGTAA GAGCCCCAAA ACGATGAAGA AGTTTCTTCA CAAAAGAAAG 
ACGGAGAGAA AGACATCCGA GGAAGAATAC GTGATTAGGA AAAGTACTGC TGCCCTGGAA 
GAGGATGCTC AGATTCTTAA GGTGATTGAA GCTTATTGCA CCAGCGCCAG TTTTCAACAA 
GGTACTCGTA AAGATTCAGT TCCACAAGTA CTCCTCCCCG AGGAAGAGAA ACTCATTATT 
GAAGAAACTA GAAGTAATGG GCAGACCATC ATTGAAGAGA AGAGCCTTGT TGATACTGTC 
TATGCCTTGA AGGATGAGGT CAAGGAATTG AAGCAGGAGA ATAAAAAAAT GAAGCAATGT 
CTGGAAGAAG AATTGAAGTC GAGGAAGGAC CTAGAAAAAC TGGTCCGGAA GCTGTTGAAG 
CAAACCGATG AATGCATTCG CGCTGAATCC AGCAGCAAGA CCTCGATTCT TCAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Arhgef6 ( NM_001005565.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001005565.1 Rattus norvegicus Rac/Cdc42 guanine nucleotide exchange factor 6 (Arhgef6), mRNA.

Price & Availability↑

CloneID	ORa42454
Clone ID Related Accession (Same CDS sequence)	NM_001005565.1
Accession Version	NM_001005565.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2319bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-15
Organism	Rattus norvegicus(Norway rat)
Product	rho guanine nucleotide exchange factor 6
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY725848.1. On Oct 8, 2004 this sequence version replaced XM_343833.1. ##Evidence-Data-START## Transcript exon combination :: AY725848.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGAATCCAG AAGAACGCGT TGTGACCTGG CTTATATCTT TGGGAGTTCT AGAGTCCCCC 
AAAAAGACCA TCTGTGATCC AGAAGAGTTC TTGAAGTCTT CGCTGAAAAA TGGGGTAGTG 
TTGTGCAAAC TCATAAGCAG ACTTCTGCCT GGCTCGGTGG AGAAGTATTG TCAGGAACCC 
CAAACTGAGG CCGACTGCAT CGACAACATC AATGACTTCC TGAAAGGATG TGCAACCCTT 
CAAGTGGAAG TGTTTGAGCC TGATGACCTC TATTCTGGGG CCAATTTCTC CAAGGTTCTG 
AATACCCTTC TAGCTGTCAA CAAAGCGACA GAAGATCAGC TATCAGAAAG ACCATGTGGA 
CGGTCCTCTT CTCTTAGTGC TACGACCAGC TCTCAGACAA ACCCACAGGC AGCCGTTCCC 
AGCACAACTC CAGAGCAGCA AAGCGAGGAA AAGGCAGCGG AGATGACGGA AAATGGAAGT 
CACCAGTTGA TAGTAAAGGC AAGATTCAAC TTCAAGCAGA CCAATGAAGA TGAATTGTCA 
GTGTGTAAAG GGGACATCAT TTATGTCACT CGAGTTGAAG AAGGAGGCTG GTGGGAAGGC 
ACATTAAATG GGAGAACCGG ATGGTTCCCT AGTAATTATG TTCGAGAAAT TAAACCCAGT 
GAGAGACCTC TGTCCCCTAA GGCTGTCAAA GGATTTGACA CTGCTCCACT TACCAAGAAT 
TACTACACTG TGGTGTTACA GAACATCTTG GACACTGAAA AAGAATATGC CAAAGAACTT 
CAGTCTCTTC TTGTTACTTA CCTAAGACCT TTGCAGTCTA ATAACAACCT GAGTACTGTG 
GAGTTTACAT GCTTATTGGG AAACTTTGAA GAAGTATGCA CATTTCAACA GACACTCTGC 
CAAGCCCTGG AAGAATGCTC AAAGTCTCCA GAAAACCAGC ACAAAGTAGG AGGCTGCCTA 
CTGAACCTCA TGCCTCATTT TAAATCGATG TACCTGGCTT ACTGTGCAAA TCATCCTTCA 
GCTGTCAACG TGCTCACCCA GCATAGTGAT GATCTAGAAC GATTCATGGA AAATCAAGGT 
GCATCCAGCC CCGGTATCCT CATTTTAACA ACAAGTCTCA GCAAACCATT CATGCGACTG 
GAAAAGTATG TTACTCTCTT GCAAGAACTG GAACGGCATA TGGAGGACAC TCATCCAGAT 
CATCAGGATA TTCTGAAAGC TATCATAGCA TTCAAAAGCC TCATGGGGCA GTGCCAAGAT 
CTGAGAAAGA GAAAGCAGCT GGAATTGCAG ATCCTTTCGG AACCTATTCA GGCATGGGAA 
GGAGATGATA TTAAGACTTT GGGAAATGTG ATCTTTATGT CACAAGTAGT GATGCAGCAT 
GGAGCCTGTG AGGAAAAAGA GGAACGATAT TTTCTGCTCT TTTCAAGTGT CTTGATCATG 
TTGTCTGCAA GTCCGCGGAT GAGTGGCTTT ATGTATCAGG GAAAGGTACC AATAGCAGGG 
ATGGTCGTGA CCAGATTGGA TGAAATTGAA GGAAATGACT GTACATTCGA AATCACCGGT 
AGCACGGTAG AGAGAATTGT GGTCCACTGC AACAATAACC AGGACTTCCA GGAGTGGATG 
GAGCAGCTGA ACAGACTGAC CAAAGGACCA GCCTCCTGCA GTTCATTGTC TAAGACCTCC 
TCATCATCAT GTAGTACTCA TTCTTCTTTT AGCTCTACCG GACAGCCCCG AGGACCCTTG 
GAGCCTCCTC AAATTATAAA ACCGTGGAGT TTAAGTTGCC TACGACCTGC ACCTCCACTT 
AGACCATCAG CAGCACTAGG TTATAAAGAG AGGATGTCTT ATATCTTAAA GGAATCTAGT 
AAGAGCCCCA AAACGATGAA GAAATTTCTT CACAAAAGAA AGACGGAGAG AAAGACATCC 
GAGGAAGAAT ACGTGATTAG GAAAAGTACT GCTGCCCTGG AAGAGGATGC TCAGATTCTT 
AAGGTGATTG AAGCTTATTG CACCAGCGCC AGTTTTCAAC AAGGTACTCG TAAAGATTCA 
GTTCCACAAG TACTACTCCC CGAGGAAGAG AAACTCATTA TTGAAGAAAC TAGAAGTAAT 
GGGCAGACCA TCATTGAAGA GAAGAGCCTT GTTGATACTG TCTATGCCTT GAAGGATGAG 
GTCAAGGAAT TGAAGCAGGA GAATAAAAAA ATGAAGCAAT GTCTGGAAGA AGAATTGAAG 
TCGAGGAAGG ACCTAGAAAA ACTGGTCCGG AAGCTGTTGA AGCAAACCGA TGAAAGCATT 
CGCGCTGAAT CCAGCAGCAA GACCTCGATT CTCCAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001005565.1
CDS	1..2319
Translation	MNPEERVVTWLISLGVLESPKKTICDPEEFLKSSLKNGVVLCKLISRLLPGSVEKYCQEPQTEADCIDNINDFLKGCATLQVEVFEPDDLYSGANFSKVLNTLLAVNKATEDQLSERPCGRSSSLSATTSSQTNPQAAVPSTTPEQQSEEKAAEMTENGSHQLIVKARFNFKQTNEDELSVCKGDIIYVTRVEEGGWWEGTLNGRTGWFPSNYVREIKPSERPLSPKAVKGFDTAPLTKNYYTVVLQNILDTEKEYAKELQSLLVTYLRPLQSNNNLSTVEFTCLLGNFEEVCTFQQTLCQALEECSKSPENQHKVGGCLLNLMPHFKSMYLAYCANHPSAVNVLTQHSDDLERFMENQGASSPGILILTTSLSKPFMRLEKYVTLLQELERHMEDTHPDHQDILKAIIAFKSLMGQCQDLRKRKQLELQILSEPIQAWEGDDIKTLGNVIFMSQVVMQHGACEEKEERYFLLFSSVLIMLSASPRMSGFMYQGKVPIAGMVVTRLDEIEGNDCTFEITGSTVERIVVHCNNNQDFQEWMEQLNRLTKGPASCSSLSKTSSSSCSTHSSFSSTGQPRGPLEPPQIIKPWSLSCLRPAPPLRPSAALGYKERMSYILKESSKSPKTMKKFLHKRKTERKTSEEEYVIRKSTAALEEDAQILKVIEAYCTSASFQQGTRKDSVPQVLLPEEEKLIIEETRSNGQTIIEEKSLVDTVYALKDEVKELKQENKKMKQCLEEELKSRKDLEKLVRKLLKQTDESIRAESSSKTSILQ

Target ORF information:

RefSeq Version	NM_001005565.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus Rac/Cdc42 guanine nucleotide exchange factor 6 (Arhgef6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001005565.1

ORF Insert Sequence:

ATGAATCCAG AAGAACGCGT TGTGACCTGG CTTATATCTT TGGGAGTTCT AGAGTCCCCC 
AAAAAGACCA TCTGTGATCC AGAAGAGTTC TTGAAGTCTT CGCTGAAAAA TGGGGTAGTG 
TTGTGCAAAC TCATAAGCAG ACTTCTGCCT GGCTCGGTGG AGAAGTATTG TCAGGAACCC 
CAAACTGAGG CCGACTGCAT CGACAACATC AATGACTTCC TGAAAGGATG TGCAACCCTT 
CAAGTGGAAG TGTTTGAGCC TGATGACCTC TATTCTGGGG CCAATTTCTC CAAGGTTCTG 
AATACCCTTC TAGCTGTCAA CAAAGCGACA GAAGATCAGC TATCAGAAAG ACCATGTGGA 
CGGTCCTCTT CTCTTAGTGC TACGACCAGC TCTCAGACAA ACCCACAGGC AGCCGTTCCC 
AGCACAACTC CAGAGCAGCA AAGCGAGGAA AAGGCAGCGG AGATGACGGA AAATGGAAGT 
CACCAGTTGA TAGTAAAGGC AAGATTCAAC TTCAAGCAGA CCAATGAAGA TGAATTGTCA 
GTGTGTAAAG GGGACATCAT TTATGTCACT CGAGTTGAAG AAGGAGGCTG GTGGGAAGGC 
ACATTAAATG GGAGAACCGG ATGGTTCCCT AGTAATTATG TTCGAGAAAT TAAACCCAGT 
GAGAGACCTC TGTCCCCTAA GGCTGTCAAA GGATTTGACA CTGCTCCACT TACCAAGAAT 
TACTACACTG TGGTGTTACA GAACATCTTG GACACTGAAA AAGAATATGC CAAAGAACTT 
CAGTCTCTTC TTGTTACTTA CCTAAGACCT TTGCAGTCTA ATAACAACCT GAGTACTGTG 
GAGTTTACAT GCTTATTGGG AAACTTTGAA GAAGTATGCA CATTTCAACA GACACTCTGC 
CAAGCCCTGG AAGAATGCTC AAAGTCTCCA GAAAACCAGC ACAAAGTAGG AGGCTGCCTA 
CTGAACCTCA TGCCTCATTT TAAATCGATG TACCTGGCTT ACTGTGCAAA TCATCCTTCA 
GCTGTCAACG TGCTCACCCA GCATAGTGAT GATCTAGAAC GATTCATGGA AAATCAAGGT 
GCATCCAGCC CCGGTATCCT CATTTTAACA ACAAGTCTCA GCAAACCATT CATGCGACTG 
GAAAAGTATG TTACTCTCTT GCAAGAACTG GAACGGCATA TGGAGGACAC TCATCCAGAT 
CATCAGGATA TTCTGAAAGC TATCATAGCA TTCAAAAGCC TCATGGGGCA GTGCCAAGAT 
CTGAGAAAGA GAAAGCAGCT GGAATTGCAG ATCCTTTCGG AACCTATTCA GGCATGGGAA 
GGAGATGATA TTAAGACTTT GGGAAATGTG ATCTTTATGT CACAAGTAGT GATGCAGCAT 
GGAGCCTGTG AGGAAAAAGA GGAACGATAT TTTCTGCTCT TTTCAAGTGT CTTGATCATG 
TTGTCTGCAA GTCCGCGGAT GAGTGGCTTT ATGTATCAGG GAAAGGTACC AATAGCAGGG 
ATGGTCGTGA CCAGATTGGA TGAAATTGAA GGAAATGACT GTACATTCGA AATCACCGGT 
AGCACGGTAG AGAGAATTGT GGTCCACTGC AACAATAACC AGGACTTCCA GGAGTGGATG 
GAGCAGCTGA ACAGACTGAC CAAAGGACCA GCCTCCTGCA GTTCATTGTC TAAGACCTCC 
TCATCATCAT GTAGTACTCA TTCTTCTTTT AGCTCTACCG GACAGCCCCG AGGACCCTTG 
GAGCCTCCTC AAATTATAAA ACCGTGGAGT TTAAGTTGCC TACGACCTGC ACCTCCACTT 
AGACCATCAG CAGCACTAGG TTATAAAGAG AGGATGTCTT ATATCTTAAA GGAATCTAGT 
AAGAGCCCCA AAACGATGAA GAAATTTCTT CACAAAAGAA AGACGGAGAG AAAGACATCC 
GAGGAAGAAT ACGTGATTAG GAAAAGTACT GCTGCCCTGG AAGAGGATGC TCAGATTCTT 
AAGGTGATTG AAGCTTATTG CACCAGCGCC AGTTTTCAAC AAGGTACTCG TAAAGATTCA 
GTTCCACAAG TACTACTCCC CGAGGAAGAG AAACTCATTA TTGAAGAAAC TAGAAGTAAT 
GGGCAGACCA TCATTGAAGA GAAGAGCCTT GTTGATACTG TCTATGCCTT GAAGGATGAG 
GTCAAGGAAT TGAAGCAGGA GAATAAAAAA ATGAAGCAAT GTCTGGAAGA AGAATTGAAG 
TCGAGGAAGG ACCTAGAAAA ACTGGTCCGG AAGCTGTTGA AGCAAACCGA TGAAAGCATT 
CGCGCTGAAT CCAGCAGCAA GACCTCGATT CTCCAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Arhgef6 ( XM_008773651.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008771873.1 Rattus norvegicus Rac/Cdc42 guanine nucleotide exchange factor 6 (Arhgef6), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa48591
Clone ID Related Accession (Same CDS sequence)	XM_008773651.2
Accession Version	XM_008773651.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2370bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	rho guanine nucleotide exchange factor 6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005120.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008773651.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAATCAC GGATGTGGCT TAGTCCTCAC AGCTGCCCCG AGAGCTGTTC AGAGCGTACG 
AGAGCCTCAG TCATGAATCC AGAAGAACGC GTTGTGACCT GGCTTATATC TTTGGGAGTT 
CTAGAGTCCC CCAAAAAGAC CATCTGTGAT CCAGAAGAGT TCTTGAAGTC TTCGCTGAAA 
AATGGGGTAG TGTTGTGCAA ACTCATAAGC AGACTTCTGC CTGGCTCGGT GGAGAAGTAT 
TGTCAGGAAC CCCAAACTGA GGCCGACTGC ATCGACAACA TCAATGACTT CCTGAAAGGA 
TGTGCAACCC TTCAAGTGGA AGTGTTTGAG CCTGATGACC TCTATTCTGG GGCCAATTTC 
TCCAAGGTTC TGAATACCCT TCTAGCTGTC AACAAAGCGA CAGAAGATCA GCTATCAGAA 
AGACCATGTG GACGGTCCTC TTCTCTTAGT GCTACGACCA GCTCTCAGAC AAACCCACAG 
GCAGCCGTTC CCAGCACAAC TCCAGAGCAG CAAAGCGAGG AAAAGGCAGC GGAGATGACG 
GAAAATGGAA GTCACCAGTT GATAGTAAAG GCAAGATTCA ACTTCAAGCA GACCAATGAA 
GATGAATTGT CAGTGTGTAA AGGGGACATC ATTTATGTCA CTCGAGTTGA AGAAGGAGGC 
TGGTGGGAAG GCACATTAAA TGGGAGAACC GGATGGTTCC CTAGTAATTA TGTTCGAGAA 
ATTAAACCCA GTGAGAGACC TCTGTCCCCT AAGGCTGTCA AAGGATTTGA CACTGCTCCA 
CTTACCAAGA ATTACTACAC TGTGGTGTTA CAGAACATCT TGGACACTGA AAAAGAATAT 
GCCAAAGAAC TTCAGTCTCT TCTTGTTACT TACCTAAGAC CTTTGCAGTC TAATAACAAC 
CTGAGTACTG TGGAGTTTAC ATGCTTATTG GGAAACTTTG AAGAAGTATG CACATTTCAA 
CAGACACTCT GCCAAGCCCT GGAAGAATGC TCAAAGTCTC CAGAAAACCA GCACAAAGTA 
GGAGGCTGCC TACTGAACCT CATGCCTCAT TTTAAATCGA TGTACCTGGC TTACTGTGCA 
AATCATCCTT CAGCTGTCAA CGTGCTCACC CAGCATAGTG ATGATCTAGA ACGATTCATG 
GAAAATCAAG GTGCATCCAG CCCCGGTATC CTCATTTTAA CAACAAGTCT CAGCAAACCA 
TTCATGCGAC TGGAAAAGTA TGTTACTCTC TTGCAAGAAC TGGAACGGCA TATGGAGGAC 
ACTCATCCAG ATCATCAGGA TATTCTGAAA GCTATCATAG CATTCAAAAG CCTCATGGGG 
CAGTGCCAAG ATCTGAGAAA GAGAAAGCAG CTGGAATTGC AGATCCTTTC GGAACCTATT 
CAGGCATGGG AAGGAGATGA TATTAAGACT TTGGGAAATG TGATCTTTAT GTCACAAGTA 
GTGATGCAGC ATGGAGCCTG TGAGGAAAAA GAGGAACGAT ATTTTCTGCT CTTTTCAAGT 
GTCTTGATCA TGTTGTCTGC AAGTCCGCGG ATGAGTGGCT TTATGTATCA GGGAAAGGTA 
CCAATAGCAG GGATGGTCGT GACCAGATTG GATGAAATTG AAGGAAATGA CTGTACATTC 
GAAATCACCG GTAGCACGGT AGAGAGAATT GTGGTCCACT GCAACAATAA CCAGGACTTC 
CAGGAGTGGA TGGAGCAGCT GAACAGACTG ACCAAAGGAC CAGCCTCCTG CAGTTCATTG 
TCTAAGACCT CCTCATCATC ATGTAGTACT CATTCTTCTT TTAGCTCTAC CGGACAGCCC 
CGAGGACCCT TGGAGCCTCC TCAAATTATA AAACCGTGGA GTTTAAGTTG CCTACGACCT 
GCACCTCCAC TTAGACCATC AGCAGCACTA GGTTATAAAG AGGAATCTAG TAAGAGCCCC 
AAAACGATGA AGAAGTTTCT TCACAAAAGA AAGACGGAGA GAAAGACATC CGAGGAAGAA 
TACGTGATTA GGAAAAGTAC TGCTGCCCTG GAAGAGGATG CTCAGATTCT TAAGGTGATT 
GAAGCTTATT GCACCAGCGC CAGTTTTCAA CAAGGTACTC GTAAAGATTC AGTTCCACAA 
GTACTCCTCC CCGAGGAAGA GAAACTCATT ATTGAAGAAA CTAGAAGTAA TGGGCAGACC 
ATCATTGAAG AGAAGAGCCT TGTTGATACT GTCTATGCCT TGAAGGATGA GGTCAAGGAA 
TTGAAGCAGG AGAATAAAAA AATGAAGCAA TGTCTGGAAG AAGAATTGAA GTCGAGGAAG 
GACCTAGAAA AACTGGTCCG GAAGCTGTTG AAGCAAACCG ATGAATGCAT TCGCGCTGAA 
TCCAGCAGCA AGACCTCGAT TCTTCAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008771873.1
CDS	468..2837
Translation	MQSRMWLSPHSCPESCSERTRASVMNPEERVVTWLISLGVLESPKKTICDPEEFLKSSLKNGVVLCKLISRLLPGSVEKYCQEPQTEADCIDNINDFLKGCATLQVEVFEPDDLYSGANFSKVLNTLLAVNKATEDQLSERPCGRSSSLSATTSSQTNPQAAVPSTTPEQQSEEKAAEMTENGSHQLIVKARFNFKQTNEDELSVCKGDIIYVTRVEEGGWWEGTLNGRTGWFPSNYVREIKPSERPLSPKAVKGFDTAPLTKNYYTVVLQNILDTEKEYAKELQSLLVTYLRPLQSNNNLSTVEFTCLLGNFEEVCTFQQTLCQALEECSKSPENQHKVGGCLLNLMPHFKSMYLAYCANHPSAVNVLTQHSDDLERFMENQGASSPGILILTTSLSKPFMRLEKYVTLLQELERHMEDTHPDHQDILKAIIAFKSLMGQCQDLRKRKQLELQILSEPIQAWEGDDIKTLGNVIFMSQVVMQHGACEEKEERYFLLFSSVLIMLSASPRMSGFMYQGKVPIAGMVVTRLDEIEGNDCTFEITGSTVERIVVHCNNNQDFQEWMEQLNRLTKGPASCSSLSKTSSSSCSTHSSFSSTGQPRGPLEPPQIIKPWSLSCLRPAPPLRPSAALGYKEESSKSPKTMKKFLHKRKTERKTSEEEYVIRKSTAALEEDAQILKVIEAYCTSASFQQGTRKDSVPQVLLPEEEKLIIEETRSNGQTIIEEKSLVDTVYALKDEVKELKQENKKMKQCLEEELKSRKDLEKLVRKLLKQTDECIRAESSSKTSILQ

Target ORF information:

RefSeq Version	XM_008773651.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus Rac/Cdc42 guanine nucleotide exchange factor 6 (Arhgef6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008773651.2

ORF Insert Sequence:

ATGCAATCAC GGATGTGGCT TAGTCCTCAC AGCTGCCCCG AGAGCTGTTC AGAGCGTACG 
AGAGCCTCAG TCATGAATCC AGAAGAACGC GTTGTGACCT GGCTTATATC TTTGGGAGTT 
CTAGAGTCCC CCAAAAAGAC CATCTGTGAT CCAGAAGAGT TCTTGAAGTC TTCGCTGAAA 
AATGGGGTAG TGTTGTGCAA ACTCATAAGC AGACTTCTGC CTGGCTCGGT GGAGAAGTAT 
TGTCAGGAAC CCCAAACTGA GGCCGACTGC ATCGACAACA TCAATGACTT CCTGAAAGGA 
TGTGCAACCC TTCAAGTGGA AGTGTTTGAG CCTGATGACC TCTATTCTGG GGCCAATTTC 
TCCAAGGTTC TGAATACCCT TCTAGCTGTC AACAAAGCGA CAGAAGATCA GCTATCAGAA 
AGACCATGTG GACGGTCCTC TTCTCTTAGT GCTACGACCA GCTCTCAGAC AAACCCACAG 
GCAGCCGTTC CCAGCACAAC TCCAGAGCAG CAAAGCGAGG AAAAGGCAGC GGAGATGACG 
GAAAATGGAA GTCACCAGTT GATAGTAAAG GCAAGATTCA ACTTCAAGCA GACCAATGAA 
GATGAATTGT CAGTGTGTAA AGGGGACATC ATTTATGTCA CTCGAGTTGA AGAAGGAGGC 
TGGTGGGAAG GCACATTAAA TGGGAGAACC GGATGGTTCC CTAGTAATTA TGTTCGAGAA 
ATTAAACCCA GTGAGAGACC TCTGTCCCCT AAGGCTGTCA AAGGATTTGA CACTGCTCCA 
CTTACCAAGA ATTACTACAC TGTGGTGTTA CAGAACATCT TGGACACTGA AAAAGAATAT 
GCCAAAGAAC TTCAGTCTCT TCTTGTTACT TACCTAAGAC CTTTGCAGTC TAATAACAAC 
CTGAGTACTG TGGAGTTTAC ATGCTTATTG GGAAACTTTG AAGAAGTATG CACATTTCAA 
CAGACACTCT GCCAAGCCCT GGAAGAATGC TCAAAGTCTC CAGAAAACCA GCACAAAGTA 
GGAGGCTGCC TACTGAACCT CATGCCTCAT TTTAAATCGA TGTACCTGGC TTACTGTGCA 
AATCATCCTT CAGCTGTCAA CGTGCTCACC CAGCATAGTG ATGATCTAGA ACGATTCATG 
GAAAATCAAG GTGCATCCAG CCCCGGTATC CTCATTTTAA CAACAAGTCT CAGCAAACCA 
TTCATGCGAC TGGAAAAGTA TGTTACTCTC TTGCAAGAAC TGGAACGGCA TATGGAGGAC 
ACTCATCCAG ATCATCAGGA TATTCTGAAA GCTATCATAG CATTCAAAAG CCTCATGGGG 
CAGTGCCAAG ATCTGAGAAA GAGAAAGCAG CTGGAATTGC AGATCCTTTC GGAACCTATT 
CAGGCATGGG AAGGAGATGA TATTAAGACT TTGGGAAATG TGATCTTTAT GTCACAAGTA 
GTGATGCAGC ATGGAGCCTG TGAGGAAAAA GAGGAACGAT ATTTTCTGCT CTTTTCAAGT 
GTCTTGATCA TGTTGTCTGC AAGTCCGCGG ATGAGTGGCT TTATGTATCA GGGAAAGGTA 
CCAATAGCAG GGATGGTCGT GACCAGATTG GATGAAATTG AAGGAAATGA CTGTACATTC 
GAAATCACCG GTAGCACGGT AGAGAGAATT GTGGTCCACT GCAACAATAA CCAGGACTTC 
CAGGAGTGGA TGGAGCAGCT GAACAGACTG ACCAAAGGAC CAGCCTCCTG CAGTTCATTG 
TCTAAGACCT CCTCATCATC ATGTAGTACT CATTCTTCTT TTAGCTCTAC CGGACAGCCC 
CGAGGACCCT TGGAGCCTCC TCAAATTATA AAACCGTGGA GTTTAAGTTG CCTACGACCT 
GCACCTCCAC TTAGACCATC AGCAGCACTA GGTTATAAAG AGGAATCTAG TAAGAGCCCC 
AAAACGATGA AGAAGTTTCT TCACAAAAGA AAGACGGAGA GAAAGACATC CGAGGAAGAA 
TACGTGATTA GGAAAAGTAC TGCTGCCCTG GAAGAGGATG CTCAGATTCT TAAGGTGATT 
GAAGCTTATT GCACCAGCGC CAGTTTTCAA CAAGGTACTC GTAAAGATTC AGTTCCACAA 
GTACTCCTCC CCGAGGAAGA GAAACTCATT ATTGAAGAAA CTAGAAGTAA TGGGCAGACC 
ATCATTGAAG AGAAGAGCCT TGTTGATACT GTCTATGCCT TGAAGGATGA GGTCAAGGAA 
TTGAAGCAGG AGAATAAAAA AATGAAGCAA TGTCTGGAAG AAGAATTGAA GTCGAGGAAG 
GACCTAGAAA AACTGGTCCG GAAGCTGTTG AAGCAAACCG ATGAATGCAT TCGCGCTGAA 
TCCAGCAGCA AGACCTCGAT TCTTCAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Arhgef6 ( XM_008773652.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008771874.1 Rattus norvegicus Rac/Cdc42 guanine nucleotide exchange factor 6 (Arhgef6), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa48592
Clone ID Related Accession (Same CDS sequence)	XM_008773652.2
Accession Version	XM_008773652.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2265bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	rho guanine nucleotide exchange factor 6 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005120.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008773652.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAATCAC GGATGTGGCT TAGTCCTCAC AGCTGCCCCG AGAGCTGTTC AGAGCGTACG 
AGAGCCTCAG TCATGAATCC AGAAGAACGC GTTGTGACCT GGCTTATATC TTTGGGAGTT 
CTAGAGTCCC CCAAAAAGAC CATCTGTGAT CCAGAAGAGT TCTTGAAGTC TTCGCTGAAA 
AATGGGGTAG TGTTGTGCAA ACTCATAAGC AGACTTCTGC CTGGCTCGGT GGAGAAGTAT 
TGTCAGGAAC CCCAAACTGA GGCCGACTGC ATCGACAACA TCAATGACTT CCTGAAAGGA 
TGTGCAACCC TTCAAGTGGA AGTGTTTGAG CCTGATGACC TCTATTCTGG GGCCAATTTC 
TCCAAGGTTC TGAATACCCT TCTAGCTGTC AACAAAGCGA CAGAAGATCA GCTATCAGAA 
AGACCATGTG GACGGTCCTC TTCTCTTAGT GCTACGACCA GCTCTCAGAC AAACCCACAG 
GCAGCCGTTC CCAGCACAAC TCCAGAGCAG CAAAGCGAGG AAAAGGCAGC GGAGATGACG 
GAAAATGGAA GTCACCAGTT GATAGTAAAG GCAAGATTCA ACTTCAAGCA GACCAATGAA 
GATGAATTGT CAGTGTGTAA AGGGGACATC ATTTATGTCA CTCGAGTTGA AGAAGGAGGC 
TGGTGGGAAG GCACATTAAA TGGGAGAACC GGATGGTTCC CTAGTAATTA TGTTCGAGAA 
ATTAAACCCA GTGAGAGACC TCTGTCCCCT AAGGCTGTCA AAGGATTTGA CACTGCTCCA 
CTTACCAAGA ATTACTACAC TGTGGTGTTA CAGAACATCT TGGACACTGA AAAAGAATAT 
GCCAAAGAAC TTCAGTCTCT TCTTGTTACT TACCTAAGAC CTTTGCAGTC TAATAACAAC 
CTGAGTACTG TGGAGTTTAC ATGCTTATTG GGAAACTTTG AAGAAGTATG CACATTTCAA 
CAGACACTCT GCCAAGCCCT GGAAGAATGC TCAAAGTCTC CAGAAAACCA GCACAAAGTA 
GGAGGCTGCC TACTGAACCT CATGCCTCAT TTTAAATCGA TGTACCTGGC TTACTGTGCA 
AATCATCCTT CAGCTGTCAA CGTGCTCACC CAGCATAGTG ATGATCTAGA ACGATTCATG 
GAAAATCAAG GTGCATCCAG CCCCGGTATC CTCATTTTAA CAACAAGTCT CAGCAAACCA 
TTCATGCGAC TGGAAAAGTA TGTTACTCTC TTGCAAGAAC TGGAACGGCA TATGGAGGAC 
ACTCATCCAG ATCATCAGGA TATTCTGAAA GCTATCATAG CATTCAAAAG CCTCATGGGG 
CAGTGCCAAG ATCTGAGAAA GAGAAAGCAG CTGGAATTGC AGATCCTTTC GGAACCTATT 
CAGGCATGGG AAGGAGATGA TATTAAGACT TTGGGAAATG TGATCTTTAT GTCACAAGTA 
GTGATGCAGC ATGGAGCCTG TGAGGAAAAA GAGGAACGAT ATTTTCTGCT CTTTTCAAGT 
GTCTTGATCA TGTTGTCTGC AAGTCCGCGG ATGAGTGGCT TTATGTATCA GGGAAAGGTA 
CCAATAGCAG GGATGGTCGT GACCAGATTG GATGAAATTG AAGGAAATGA CTGTACATTC 
GAAATCACCG GTAGCACGGT AGAGAGAATT GTGGTCCACT GCAACAATAA CCAGGACTTC 
CAGGAGTGGA TGGAGCAGCT GAACAGACTG ACCAAAGGAC CAGCCTCCTG CAGTTCATTG 
TCTAAGACCT CCTCATCATC ATGTAGTACT CATTCTAGGA TGTCTTATAT CTTAAAGGAA 
TCTAGTAAGA GCCCCAAAAC GATGAAGAAG TTTCTTCACA AAAGAAAGAC GGAGAGAAAG 
ACATCCGAGG AAGAATACGT GATTAGGAAA AGTACTGCTG CCCTGGAAGA GGATGCTCAG 
ATTCTTAAGG TGATTGAAGC TTATTGCACC AGCGCCAGTT TTCAACAAGG TACTCGTAAA 
GATTCAGTTC CACAAGTACT CCTCCCCGAG GAAGAGAAAC TCATTATTGA AGAAACTAGA 
AGTAATGGGC AGACCATCAT TGAAGAGAAG AGCCTTGTTG ATACTGTCTA TGCCTTGAAG 
GATGAGGTCA AGGAATTGAA GCAGGAGAAT AAAAAAATGA AGCAATGTCT GGAAGAAGAA 
TTGAAGTCGA GGAAGGACCT AGAAAAACTG GTCCGGAAGC TGTTGAAGCA AACCGATGAA 
TGCATTCGCG CTGAATCCAG CAGCAAGACC TCGATTCTTC AGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008771874.1
CDS	469..2733
Translation	MQSRMWLSPHSCPESCSERTRASVMNPEERVVTWLISLGVLESPKKTICDPEEFLKSSLKNGVVLCKLISRLLPGSVEKYCQEPQTEADCIDNINDFLKGCATLQVEVFEPDDLYSGANFSKVLNTLLAVNKATEDQLSERPCGRSSSLSATTSSQTNPQAAVPSTTPEQQSEEKAAEMTENGSHQLIVKARFNFKQTNEDELSVCKGDIIYVTRVEEGGWWEGTLNGRTGWFPSNYVREIKPSERPLSPKAVKGFDTAPLTKNYYTVVLQNILDTEKEYAKELQSLLVTYLRPLQSNNNLSTVEFTCLLGNFEEVCTFQQTLCQALEECSKSPENQHKVGGCLLNLMPHFKSMYLAYCANHPSAVNVLTQHSDDLERFMENQGASSPGILILTTSLSKPFMRLEKYVTLLQELERHMEDTHPDHQDILKAIIAFKSLMGQCQDLRKRKQLELQILSEPIQAWEGDDIKTLGNVIFMSQVVMQHGACEEKEERYFLLFSSVLIMLSASPRMSGFMYQGKVPIAGMVVTRLDEIEGNDCTFEITGSTVERIVVHCNNNQDFQEWMEQLNRLTKGPASCSSLSKTSSSSCSTHSRMSYILKESSKSPKTMKKFLHKRKTERKTSEEEYVIRKSTAALEEDAQILKVIEAYCTSASFQQGTRKDSVPQVLLPEEEKLIIEETRSNGQTIIEEKSLVDTVYALKDEVKELKQENKKMKQCLEEELKSRKDLEKLVRKLLKQTDECIRAESSSKTSILQ

Target ORF information:

RefSeq Version	XM_008773652.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus Rac/Cdc42 guanine nucleotide exchange factor 6 (Arhgef6), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008773652.2

ORF Insert Sequence:

ATGCAATCAC GGATGTGGCT TAGTCCTCAC AGCTGCCCCG AGAGCTGTTC AGAGCGTACG 
AGAGCCTCAG TCATGAATCC AGAAGAACGC GTTGTGACCT GGCTTATATC TTTGGGAGTT 
CTAGAGTCCC CCAAAAAGAC CATCTGTGAT CCAGAAGAGT TCTTGAAGTC TTCGCTGAAA 
AATGGGGTAG TGTTGTGCAA ACTCATAAGC AGACTTCTGC CTGGCTCGGT GGAGAAGTAT 
TGTCAGGAAC CCCAAACTGA GGCCGACTGC ATCGACAACA TCAATGACTT CCTGAAAGGA 
TGTGCAACCC TTCAAGTGGA AGTGTTTGAG CCTGATGACC TCTATTCTGG GGCCAATTTC 
TCCAAGGTTC TGAATACCCT TCTAGCTGTC AACAAAGCGA CAGAAGATCA GCTATCAGAA 
AGACCATGTG GACGGTCCTC TTCTCTTAGT GCTACGACCA GCTCTCAGAC AAACCCACAG 
GCAGCCGTTC CCAGCACAAC TCCAGAGCAG CAAAGCGAGG AAAAGGCAGC GGAGATGACG 
GAAAATGGAA GTCACCAGTT GATAGTAAAG GCAAGATTCA ACTTCAAGCA GACCAATGAA 
GATGAATTGT CAGTGTGTAA AGGGGACATC ATTTATGTCA CTCGAGTTGA AGAAGGAGGC 
TGGTGGGAAG GCACATTAAA TGGGAGAACC GGATGGTTCC CTAGTAATTA TGTTCGAGAA 
ATTAAACCCA GTGAGAGACC TCTGTCCCCT AAGGCTGTCA AAGGATTTGA CACTGCTCCA 
CTTACCAAGA ATTACTACAC TGTGGTGTTA CAGAACATCT TGGACACTGA AAAAGAATAT 
GCCAAAGAAC TTCAGTCTCT TCTTGTTACT TACCTAAGAC CTTTGCAGTC TAATAACAAC 
CTGAGTACTG TGGAGTTTAC ATGCTTATTG GGAAACTTTG AAGAAGTATG CACATTTCAA 
CAGACACTCT GCCAAGCCCT GGAAGAATGC TCAAAGTCTC CAGAAAACCA GCACAAAGTA 
GGAGGCTGCC TACTGAACCT CATGCCTCAT TTTAAATCGA TGTACCTGGC TTACTGTGCA 
AATCATCCTT CAGCTGTCAA CGTGCTCACC CAGCATAGTG ATGATCTAGA ACGATTCATG 
GAAAATCAAG GTGCATCCAG CCCCGGTATC CTCATTTTAA CAACAAGTCT CAGCAAACCA 
TTCATGCGAC TGGAAAAGTA TGTTACTCTC TTGCAAGAAC TGGAACGGCA TATGGAGGAC 
ACTCATCCAG ATCATCAGGA TATTCTGAAA GCTATCATAG CATTCAAAAG CCTCATGGGG 
CAGTGCCAAG ATCTGAGAAA GAGAAAGCAG CTGGAATTGC AGATCCTTTC GGAACCTATT 
CAGGCATGGG AAGGAGATGA TATTAAGACT TTGGGAAATG TGATCTTTAT GTCACAAGTA 
GTGATGCAGC ATGGAGCCTG TGAGGAAAAA GAGGAACGAT ATTTTCTGCT CTTTTCAAGT 
GTCTTGATCA TGTTGTCTGC AAGTCCGCGG ATGAGTGGCT TTATGTATCA GGGAAAGGTA 
CCAATAGCAG GGATGGTCGT GACCAGATTG GATGAAATTG AAGGAAATGA CTGTACATTC 
GAAATCACCG GTAGCACGGT AGAGAGAATT GTGGTCCACT GCAACAATAA CCAGGACTTC 
CAGGAGTGGA TGGAGCAGCT GAACAGACTG ACCAAAGGAC CAGCCTCCTG CAGTTCATTG 
TCTAAGACCT CCTCATCATC ATGTAGTACT CATTCTAGGA TGTCTTATAT CTTAAAGGAA 
TCTAGTAAGA GCCCCAAAAC GATGAAGAAG TTTCTTCACA AAAGAAAGAC GGAGAGAAAG 
ACATCCGAGG AAGAATACGT GATTAGGAAA AGTACTGCTG CCCTGGAAGA GGATGCTCAG 
ATTCTTAAGG TGATTGAAGC TTATTGCACC AGCGCCAGTT TTCAACAAGG TACTCGTAAA 
GATTCAGTTC CACAAGTACT CCTCCCCGAG GAAGAGAAAC TCATTATTGA AGAAACTAGA 
AGTAATGGGC AGACCATCAT TGAAGAGAAG AGCCTTGTTG ATACTGTCTA TGCCTTGAAG 
GATGAGGTCA AGGAATTGAA GCAGGAGAAT AAAAAAATGA AGCAATGTCT GGAAGAAGAA 
TTGAAGTCGA GGAAGGACCT AGAAAAACTG GTCCGGAAGC TGTTGAAGCA AACCGATGAA 
TGCATTCGCG CTGAATCCAG CAGCAAGACC TCGATTCTTC AGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Arhgef6 ( XM_008773653.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008771875.1 Rattus norvegicus Rac/Cdc42 guanine nucleotide exchange factor 6 (Arhgef6), transcript variant X3, mRNA.

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CloneID	ORa48593
Clone ID Related Accession (Same CDS sequence)	XM_008773653.2
Accession Version	XM_008773653.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2244bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	rho guanine nucleotide exchange factor 6 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005120.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008773653.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAATCAC GGATGTGGCT TAGTCCTCAC AGCTGCCCCG AGAGCTGTTC AGAGCGTACG 
AGAGCCTCAG TCATGAATCC AGAAGAACGC GTTGTGACCT GGCTTATATC TTTGGGAGTT 
CTAGAGTCCC CCAAAAAGAC CATCTGTGAT CCAGAAGAGT TCTTGAAGTC TTCGCTGAAA 
AATGGGGTAG TGTTGTGCAA ACTCATAAGC AGACTTCTGC CTGGCTCGGT GGAGAAGTAT 
TGTCAGGAAC CCCAAACTGA GGCCGACTGC ATCGACAACA TCAATGACTT CCTGAAAGGA 
TGTGCAACCC TTCAAGTGGA AGTGTTTGAG CCTGATGACC TCTATTCTGG GGCCAATTTC 
TCCAAGGTTC TGAATACCCT TCTAGCTGTC AACAAAGCGA CAGAAGATCA GCTATCAGAA 
AGACCATGTG GACGGTCCTC TTCTCTTAGT GCTACGACCA GCTCTCAGAC AAACCCACAG 
GCAGCCGTTC CCAGCACAAC TCCAGAGCAG CAAAGCGAGG AAAAGGCAGC GGAGATGACG 
GAAAATGGAA GTCACCAGTT GATAGTAAAG GCAAGATTCA ACTTCAAGCA GACCAATGAA 
GATGAATTGT CAGTGTGTAA AGGGGACATC ATTTATGTCA CTCGAGTTGA AGAAGGAGGC 
TGGTGGGAAG GCACATTAAA TGGGAGAACC GGATGGTTCC CTAGTAATTA TGTTCGAGAA 
ATTAAACCCA GTGAGAGACC TCTGTCCCCT AAGGCTGTCA AAGGATTTGA CACTGCTCCA 
CTTACCAAGA ATTACTACAC TGTGGTGTTA CAGAACATCT TGGACACTGA AAAAGAATAT 
GCCAAAGAAC TTCAGTCTCT TCTTGTTACT TACCTAAGAC CTTTGCAGTC TAATAACAAC 
CTGAGTACTG TGGAGTTTAC ATGCTTATTG GGAAACTTTG AAGAAGTATG CACATTTCAA 
CAGACACTCT GCCAAGCCCT GGAAGAATGC TCAAAGTCTC CAGAAAACCA GCACAAAGTA 
GGAGGCTGCC TACTGAACCT CATGCCTCAT TTTAAATCGA TGTACCTGGC TTACTGTGCA 
AATCATCCTT CAGCTGTCAA CGTGCTCACC CAGCATAGTG ATGATCTAGA ACGATTCATG 
GAAAATCAAG GTGCATCCAG CCCCGGTATC CTCATTTTAA CAACAAGTCT CAGCAAACCA 
TTCATGCGAC TGGAAAAGTA TGTTACTCTC TTGCAAGAAC TGGAACGGCA TATGGAGGAC 
ACTCATCCAG ATCATCAGGA TATTCTGAAA GCTATCATAG CATTCAAAAG CCTCATGGGG 
CAGTGCCAAG ATCTGAGAAA GAGAAAGCAG CTGGAATTGC AGATCCTTTC GGAACCTATT 
CAGGCATGGG AAGGAGATGA TATTAAGACT TTGGGAAATG TGATCTTTAT GTCACAAGTA 
GTGATGCAGC ATGGAGCCTG TGAGGAAAAA GAGGAACGAT ATTTTCTGCT CTTTTCAAGT 
GTCTTGATCA TGTTGTCTGC AAGTCCGCGG ATGAGTGGCT TTATGTATCA GGGAAAGGTA 
CCAATAGCAG GGATGGTCGT GACCAGATTG GATGAAATTG AAGGAAATGA CTGTACATTC 
GAAATCACCG GTAGCACGGT AGAGAGAATT GTGGTCCACT GCAACAATAA CCAGGACTTC 
CAGGAGTGGA TGGAGCAGCT GAACAGACTG ACCAAAGGAC CAGCCTCCTG CAGTTCATTG 
TCTAAGACCT CCTCATCATC ATGTAGTACT CATTCTGAAT CTAGTAAGAG CCCCAAAACG 
ATGAAGAAGT TTCTTCACAA AAGAAAGACG GAGAGAAAGA CATCCGAGGA AGAATACGTG 
ATTAGGAAAA GTACTGCTGC CCTGGAAGAG GATGCTCAGA TTCTTAAGGT GATTGAAGCT 
TATTGCACCA GCGCCAGTTT TCAACAAGGT ACTCGTAAAG ATTCAGTTCC ACAAGTACTC 
CTCCCCGAGG AAGAGAAACT CATTATTGAA GAAACTAGAA GTAATGGGCA GACCATCATT 
GAAGAGAAGA GCCTTGTTGA TACTGTCTAT GCCTTGAAGG ATGAGGTCAA GGAATTGAAG 
CAGGAGAATA AAAAAATGAA GCAATGTCTG GAAGAAGAAT TGAAGTCGAG GAAGGACCTA 
GAAAAACTGG TCCGGAAGCT GTTGAAGCAA ACCGATGAAT GCATTCGCGC TGAATCCAGC 
AGCAAGACCT CGATTCTTCA GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008771875.1
CDS	466..2709
Translation	MQSRMWLSPHSCPESCSERTRASVMNPEERVVTWLISLGVLESPKKTICDPEEFLKSSLKNGVVLCKLISRLLPGSVEKYCQEPQTEADCIDNINDFLKGCATLQVEVFEPDDLYSGANFSKVLNTLLAVNKATEDQLSERPCGRSSSLSATTSSQTNPQAAVPSTTPEQQSEEKAAEMTENGSHQLIVKARFNFKQTNEDELSVCKGDIIYVTRVEEGGWWEGTLNGRTGWFPSNYVREIKPSERPLSPKAVKGFDTAPLTKNYYTVVLQNILDTEKEYAKELQSLLVTYLRPLQSNNNLSTVEFTCLLGNFEEVCTFQQTLCQALEECSKSPENQHKVGGCLLNLMPHFKSMYLAYCANHPSAVNVLTQHSDDLERFMENQGASSPGILILTTSLSKPFMRLEKYVTLLQELERHMEDTHPDHQDILKAIIAFKSLMGQCQDLRKRKQLELQILSEPIQAWEGDDIKTLGNVIFMSQVVMQHGACEEKEERYFLLFSSVLIMLSASPRMSGFMYQGKVPIAGMVVTRLDEIEGNDCTFEITGSTVERIVVHCNNNQDFQEWMEQLNRLTKGPASCSSLSKTSSSSCSTHSESSKSPKTMKKFLHKRKTERKTSEEEYVIRKSTAALEEDAQILKVIEAYCTSASFQQGTRKDSVPQVLLPEEEKLIIEETRSNGQTIIEEKSLVDTVYALKDEVKELKQENKKMKQCLEEELKSRKDLEKLVRKLLKQTDECIRAESSSKTSILQ

Target ORF information:

RefSeq Version	XM_008773653.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus Rac/Cdc42 guanine nucleotide exchange factor 6 (Arhgef6), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008773653.2

ORF Insert Sequence:

ATGCAATCAC GGATGTGGCT TAGTCCTCAC AGCTGCCCCG AGAGCTGTTC AGAGCGTACG 
AGAGCCTCAG TCATGAATCC AGAAGAACGC GTTGTGACCT GGCTTATATC TTTGGGAGTT 
CTAGAGTCCC CCAAAAAGAC CATCTGTGAT CCAGAAGAGT TCTTGAAGTC TTCGCTGAAA 
AATGGGGTAG TGTTGTGCAA ACTCATAAGC AGACTTCTGC CTGGCTCGGT GGAGAAGTAT 
TGTCAGGAAC CCCAAACTGA GGCCGACTGC ATCGACAACA TCAATGACTT CCTGAAAGGA 
TGTGCAACCC TTCAAGTGGA AGTGTTTGAG CCTGATGACC TCTATTCTGG GGCCAATTTC 
TCCAAGGTTC TGAATACCCT TCTAGCTGTC AACAAAGCGA CAGAAGATCA GCTATCAGAA 
AGACCATGTG GACGGTCCTC TTCTCTTAGT GCTACGACCA GCTCTCAGAC AAACCCACAG 
GCAGCCGTTC CCAGCACAAC TCCAGAGCAG CAAAGCGAGG AAAAGGCAGC GGAGATGACG 
GAAAATGGAA GTCACCAGTT GATAGTAAAG GCAAGATTCA ACTTCAAGCA GACCAATGAA 
GATGAATTGT CAGTGTGTAA AGGGGACATC ATTTATGTCA CTCGAGTTGA AGAAGGAGGC 
TGGTGGGAAG GCACATTAAA TGGGAGAACC GGATGGTTCC CTAGTAATTA TGTTCGAGAA 
ATTAAACCCA GTGAGAGACC TCTGTCCCCT AAGGCTGTCA AAGGATTTGA CACTGCTCCA 
CTTACCAAGA ATTACTACAC TGTGGTGTTA CAGAACATCT TGGACACTGA AAAAGAATAT 
GCCAAAGAAC TTCAGTCTCT TCTTGTTACT TACCTAAGAC CTTTGCAGTC TAATAACAAC 
CTGAGTACTG TGGAGTTTAC ATGCTTATTG GGAAACTTTG AAGAAGTATG CACATTTCAA 
CAGACACTCT GCCAAGCCCT GGAAGAATGC TCAAAGTCTC CAGAAAACCA GCACAAAGTA 
GGAGGCTGCC TACTGAACCT CATGCCTCAT TTTAAATCGA TGTACCTGGC TTACTGTGCA 
AATCATCCTT CAGCTGTCAA CGTGCTCACC CAGCATAGTG ATGATCTAGA ACGATTCATG 
GAAAATCAAG GTGCATCCAG CCCCGGTATC CTCATTTTAA CAACAAGTCT CAGCAAACCA 
TTCATGCGAC TGGAAAAGTA TGTTACTCTC TTGCAAGAAC TGGAACGGCA TATGGAGGAC 
ACTCATCCAG ATCATCAGGA TATTCTGAAA GCTATCATAG CATTCAAAAG CCTCATGGGG 
CAGTGCCAAG ATCTGAGAAA GAGAAAGCAG CTGGAATTGC AGATCCTTTC GGAACCTATT 
CAGGCATGGG AAGGAGATGA TATTAAGACT TTGGGAAATG TGATCTTTAT GTCACAAGTA 
GTGATGCAGC ATGGAGCCTG TGAGGAAAAA GAGGAACGAT ATTTTCTGCT CTTTTCAAGT 
GTCTTGATCA TGTTGTCTGC AAGTCCGCGG ATGAGTGGCT TTATGTATCA GGGAAAGGTA 
CCAATAGCAG GGATGGTCGT GACCAGATTG GATGAAATTG AAGGAAATGA CTGTACATTC 
GAAATCACCG GTAGCACGGT AGAGAGAATT GTGGTCCACT GCAACAATAA CCAGGACTTC 
CAGGAGTGGA TGGAGCAGCT GAACAGACTG ACCAAAGGAC CAGCCTCCTG CAGTTCATTG 
TCTAAGACCT CCTCATCATC ATGTAGTACT CATTCTGAAT CTAGTAAGAG CCCCAAAACG 
ATGAAGAAGT TTCTTCACAA AAGAAAGACG GAGAGAAAGA CATCCGAGGA AGAATACGTG 
ATTAGGAAAA GTACTGCTGC CCTGGAAGAG GATGCTCAGA TTCTTAAGGT GATTGAAGCT 
TATTGCACCA GCGCCAGTTT TCAACAAGGT ACTCGTAAAG ATTCAGTTCC ACAAGTACTC 
CTCCCCGAGG AAGAGAAACT CATTATTGAA GAAACTAGAA GTAATGGGCA GACCATCATT 
GAAGAGAAGA GCCTTGTTGA TACTGTCTAT GCCTTGAAGG ATGAGGTCAA GGAATTGAAG 
CAGGAGAATA AAAAAATGAA GCAATGTCTG GAAGAAGAAT TGAAGTCGAG GAAGGACCTA 
GAAAAACTGG TCCGGAAGCT GTTGAAGCAA ACCGATGAAT GCATTCGCGC TGAATCCAGC 
AGCAAGACCT CGATTCTTCA GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

c-Cbl regulates ?Pix-mediated cell migration and invasion.
Biochemical and biophysical research communications455(3-4)153-8(2014 Dec)
Seong MW,Park JH,Yoo HM,Yang SW,Oh KH,Ka SH,Park DE,Lee ST,Chung CH

The lymphoid lineage-specific actin-uncapping protein Rltpr is essential for costimulation via CD28 and the development of regulatory T cells.
Nature immunology14(8)858-66(2013 Aug)
Liang Y,Cucchetti M,Roncagalli R,Yokosuka T,Malzac A,Bertosio E,Imbert J,Nijman IJ,Suchanek M,Saito T,W?lfing C,Malissen B,Malissen M

Biochemical and functional characterisation of ?PIX, a specific regulator of axonal and dendritic branching in hippocampal neurons.
Biology of the cell104(9)533-52(2012 Sep)
Totaro A,Tavano S,Filosa G,G?rtner A,Pennucci R,Santambrogio P,Bachi A,Dotti CG,de Curtis I

betaPIX-activated Rac1 stimulates the activation of phospholipase D, which is associated with exocytosis in neuroendocrine cells.
Journal of cell science122(Pt 6)798-806(2009 Mar)
Momboisse F,Lonchamp E,Calco V,Ceridono M,Vitale N,Bader MF,Gasman S

Affixin activates Rac1 via betaPIX in C2C12 myoblast.
FEBS letters582(8)1189-96(2008 Apr)
Matsuda C,Kameyama K,Suzuki A,Mishima W,Yamaji S,Okamoto H,Nishino I,Hayashi YK

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Arhgef6 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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