Myo18a cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Myo18a
Entrez Gene ID	360570
Full Name	myosin XVIIIa
General protein information	Preferred Names myosin XVIIIa Names unconventional myosin-XVIIIa myosin 18a
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q25

mRNA and Protein(s)

mRNA	Protein	Name
NM_001172137.1	NP_001165608.1	unconventional myosin-XVIIIa

Pathways from BioSystems

Homologies

Drosophila melanogaster (fruit fly)	Mhcl	NP_001036715.1
Danio rerio (zebrafish)	myo18ab	XP_005157670.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP011138	XP_564385.3
Homo sapiens (human)	MYO18A	NP_976063.1
	MYO18A	XP_001110924.1
Bos taurus (cattle)	MYO18A	XP_003587436.1
Mus musculus (house mouse)	Myo18a	NP_035716.1
Danio rerio (zebrafish)	myo18aa	XP_695256.4
Rattus norvegicus (Norway rat)	Myo18a	NP_001165608.1
Canis lupus familiaris (dog)	MYO18A	XP_005624934.1
Gallus gallus (chicken)	MYO18A	XP_004946669.1

Gene Ontology
Bibliography

Related articles in PubMed

SP-R210 (Myo18A) Isoforms as Intrinsic Modulators of Macrophage Priming and Activation.
Yang L, Carrillo M, Wu YM, DiAngelo SL, Silveyra P, Umstead TM, Halstead ES, Davies ML, Hu S, Floros J, McCormack FX, Christensen ND, Chroneos ZC
PloS one10(5)e0126576(2015)

DNA damage triggers Golgi dispersal via DNA-PK and GOLPH3.
Farber-Katz SE, Dippold HC, Buschman MD, Peterman MC, Xing M, Noakes CJ, Tat J, Ng MM, Rahajeng J, Cowan DM, Fuchs GJ, Zhou H, Field SJ
Cell156(3)413-27(2014 Jan)

Functional characterization of human myosin-18A and its interaction with F-actin and GOLPH3.
Taft MH, Behrmann E, Munske-Weidemann LC, Thiel C, Raunser S, Manstein DJ
The Journal of biological chemistry288(42)30029-41(2013 Oct)

GOLPH3L antagonizes GOLPH3 to determine Golgi morphology.
Ng MM, Dippold HC, Buschman MD, Noakes CJ, Field SJ
Molecular biology of the cell24(6)796-808(2013 Mar)

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Baltz AG, Munschauer M, Schwanh?usser B, Vasile A, Murakawa Y, Schueler M, Youngs N, Penfold-Brown D, Drew K, Milek M, Wyler E, Bonneau R, Selbach M, Dieterich C, Landthaler M
Molecular cell46(5)674-90(2012 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Study reports that MRCK and myosin II-related MYO18A linked by the adaptor protein LRAP35a form a functional tripartite complex, which is responsible for the assembly of lamellar actomyosin bundles and of a subnuclear actomyosin network.
Title: A tripartite complex containing MRCK modulates lamellar actomyosin retrograde flow.

MyoXVIIIA constitutes a novel receptor for SP-A
Title: Identification of the surfactant protein A receptor 210 as the unconventional myosin 18A.

The following Myo18a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Myo18a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa06447	NM_001172137.1 Latest version!	Rattus norvegicus myosin XVIIIa (Myo18a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	30	$1091.30 $1559.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Myo18a ( NM_001172137.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001165608.1 Rattus norvegicus myosin XVIIIa (Myo18a), mRNA.

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CloneID	ORa06447
Clone ID Related Accession (Same CDS sequence)	NM_001172137.1
Accession Version	NM_001172137.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 6165bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-15
Organism	Rattus norvegicus(Norway rat)
Product	unconventional myosin-XVIIIa
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AAHX01064948.1, AAHX01064949.1, AAHX01064950.1 and AAHX01064951.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGTTTAACC TCATGAAGAA AGACAAGGAC AAAGATGGCG GGCGGAAGGA GAAGAAGGAG 
AAAAAGGAGA AGAAGGAGAG GATGTCTGCG GCAGAACTGC GGAGCCTGGA AGAGATGAGC 
ATGCGCCGTG GCTTTTTCAA CTTGAACCGG TCCTCCAAGC GGGAATCCAA GACGCGCCTG 
GAAATCTCCA ACCCCATCCC TATCAAGGTG GCCAGTGGCT CTGACCTGCA CCTAACCGAC 
ATTGACTCTG ACAGCAATAG GGGTAGCATC ATCCTGGATT CAGGCCACCT AAGCACAGCC 
AGCTCCAGTG ATGACCTCAA GGGTGAAGAA GGCAGCTTCC GGGGTTCTGT GCTGCAGCGG 
GCAGCTAAGT TCGGTTCACT AGCCAAGCAG AACTCTCAGA TGATTGTCAA ACGTTTTTCC 
TTTTCTCAAC GGAGCCGGGA TGAGAGTGCC TCAGAGACCT CAACCCCCTC AGAGCACTCT 
GCAGCCCCAT CACCTCAGGT AGAGGTGAGG ACGCTTGAGG GACAGCTAAT GCAGCACTCT 
GGGCTAGGCA TCCCTCGACC AGGACCCAGG TCTCGAGTCC CTGAGCTGGT GACTAAAAGA 
TTCCCAGCTG ACTTACGTCT CCCGGCTCTG GTGCCCCCAC CACCTCCTGC TCTCCGGGAG 
CTGGAGTTAC AACGACGACC CACAGGAGAC TTTGGCTTCT CACTGCGGCG CACAACCATG 
CTGGACCGGG CCCCTGAGGG TCAGGCCTAT CGACGTGTGG TTCACTTTGC TGAGCCAGGG 
GCAGGCACCA AGGACCTGGC CTTGGGGCTG GTGCCAGGAG ACCGACTGGT GGAGATTAAT 
GGACAGAATG TGGAGAATAA GTCCAGGGAT GAAATTGTGG AGATGATCCG GCAGTCTGGG 
GACAGTGTGC GGCTCAAGGT ACAGCCCATC CCAGAGCTTA GCGAGCTGAG CCGGAGCTGG 
CTTCGGACTG GCGAGGGACA CCGCAGGGAG CCGACTGATG CCAAGACAGA AGAGCAGATT 
GCCGCTGAAG AGGCCTGGTA TGAGACGGAG AAGGTGTGGC TGGTCCATAG AGATGGATTC 
TCCTTAGCCA GCCAGCTCAA GTCGGAGGAG CTCAGCCTAC CCGAGGGGAA GGTGCGCGTG 
AAGCTAGACC ACGATGGAGC CATCCTGGAT GTGGATGAAG ATGACGTAGA GAAGGCTAAC 
GCTCCCTCAT GTGACCGACT AGAAGATCTG GCCTCCTTGG TGTACCTCAA CGAGTCTAGC 
GTCCTGCATA CACTGCGCCA GCGCTATGGG GCCAGCCTGC TACACACCTA TGCCGGCCCT 
AGCCTGCTTG TCCTTAGCCC CCGAGGGGCT CCTGCTGTGT ATTCAGAGAA GGTGATGCAC 
ATGTTCAAGG GGTGTCGGCG GGAGGACATG GCACCCCACA TCTATGCTGT AGCCCAGACT 
GCATATAGGG CCATGTTGAT GAGTCGTCAG GACCAGTCCA TCGTCCTTCT GGGCAGTAGT 
GGCAGTGGCA AGACCACCAG CTCTCAGCAT CTGGTGCAGT ATCTGGCTAC CATTGCCGGC 
ACCAGCGGGA ACAAGGTGTT CTCAGTGGAG AAGTGGCAGG CTCTGGCCAC CCTCCTGGAA 
GCCTTTGGGA ACAGCCCTAC CATCATGAAC GGCAGTGCCA CCCGCTTCTC CCAGATCCTC 
TCCCTGGACT TTGACCAAGC TGGCCAGGTG GCTTCAGCCT CCGTCCAGAC CATGCTCCTG 
GAGAAGCTGC GTGTGGCCCG ACGCCCAGCC AGCGAGGCCA CTTTCAATGT CTTCTACTAC 
TTGCTGGCCT GTGGGGACAG CACCCTCAGG ACAGAGCTCC ACCTGAACCA CTTGGCAGAG 
AACAATGTGT TTGGAATTGT GCCATTGTCC AAGCCTGAGG AGAAGCAGAG GGCTGCTCAG 
CAGTTCAGTA AGCTACAGAC GGCCATGAAG GTGCTGGCCA TCTCCCCTGA GGAACAGAAG 
GCCTGCTGGC TCATCCTGGC TTCCATCTAC CACTTGGGGG CTGCTGGAGC TACCAAAGAA 
GCTGCTGAAG GTGGACGTAA GCAATTTGCC CGTCATGAAT GGGCCCAGAA GGCCGCATAC 
CTGCTAGGCT GCAGCTTGGA AGAGCTGTCC TCAGCGATCT TCAAGCACCA GCTCAAAGGC 
GGCACCCTGC AACGGTCTAC CTCCTTCCGT CAGGGCCCTG AGGAGAGCGG CCTGGGAGAG 
GGTACAGGCA CCAAGCTGAG TGCTCTGGAG TGCTTAGAGG GTATGGCGTC TGGCCTCTAC 
AGCGAGCTCT TTACTCTCCT CATCTCCCTG GTAAACAGGG CTCTCAAGTC CAGCCAGCAC 
TCACTGTGTT CCATGATGAT TGTGGATACA CCAGGCTTCC AGAACCCTGA ATGGGGTGGC 
TCAGCCCGTG GCGCCTCCTT CGAGGAGCTG TGCCACAACT ATGCCCAGGA CAGGTTGCAG 
AAGCTGTTCC ATGAGCGCAC CTTCCTCCAG GAGTTGGAAA GGTACAAGGA GGACAACATC 
GAACTGGCGT TTGATGACTT GGAGCCAGTC ACAGATGACT CAGTGGCTGC TGTGGACCAG 
GCCTCCCACC AGTCCCTGGT TCGCTCACTG GCCCATGCCG ATGAGGCAAG AGGACTACTG 
TGGCTCCTAG AAGAGGAGGC TCTGGTGCCA GGTGCGACTG AGGATACCCT CCTGGACCGT 
CTTTTCTCCT ATTATGGCCC CCAGGAAGGT GACAAAAAAG GTCAGAGTCC TCTTCTGCGC 
AGTAGCAAAC CACGGCACTT TCTCCTGGGC CACAGCCATG GTACCAACTG GGTGGAGTAC 
AATGTGACCG GCTGGCTGAA CTACACCAAG CAGAACCCAG CCACCCAGAA TGCACCCCGG 
CTCCTGCAGG ACTCCCAGAA AAAGATCATC AGCAACCTGT TTCTGGGCCG GGCAGGCACT 
GCCACAGTGC TCTCGGGCTC AATTGCAGGC CTGGAAGGTG GCTCCCAGCT GGCCTTGCGC 
CGGGCAACTA GCATGAGGAA AACCTTTACC ACTGGCATGG CAGCTGTCAA GAAGAAGTCA 
CTGTGCATAC AGATCAAGCT GCAAGTGGAT GCCCTCATCG ATACCATCAA GAGGTCCAAG 
ATGCATTTCG TGCACTGCTT CCTTCCTGTG GCCGAGGGCT GGCCTGGGGA GCCCCGATCT 
GCTTCTTCTC GCCGAGTTAG TAGCAGCAGT GAGCTGGACC TGCCTCCGGG AGACCCCTGC 
GAGGCTGGGC TGCTACAACT GGATGTGTCC CTGCTCCGTG CCCAGCTTCG GGGATCCCGC 
CTGCTTGATG CAATACGCAT GTACCGCCAA GGTTACCCAG ACCACATGGT GTTTTCTGAG 
TTCCGTAGGC GCTTTGATGT CCTGGCCCCA CACCTGACCA AGAAACATGG GCGTAACTAC 
ATCGTGGTGG ATGAGAAGCG GGCTGTGGAG GAGCTGCTGG AGTCCCTAGA CCTGGAAAAG 
AGCAGCTGCT GCATGGGCCT GAGTCGGGTA TTCTTCCGGG CAGGCACGTT GGCACGGCTG 
GAAGAGCAAC GAGACGAGGA AACCAGCAGA CACCTGACCC TGTTCCAGGC AGCCTGCAGG 
GGCTACCTTG CCCGCCAGCA CTTCAAGAAG AGAAAGATCC AGGACCTGGC CATTCGCTGT 
GTGCAGAAGA ACATCAAGAA GAACAAGGGG GTGAAGGACT GGCCCTGGTG GAAGCTCTTC 
ACCACTGTGC GGCCCCTCAT CCAAGTTCAG CTGTCTGAGG AGCAGATCCG AAACAAAGAC 
GAGGAGATCC AGCAGCTGCG AAACAAGCTT GAGAAGGTGG AGAAAGAGAG GAATGAGCTT 
CGGCTCAACA GTGACCGGCT GGAGACCCGG ATCTCAGAGC TGACATCGGA GCTGACTGAT 
GAACGCAACA CAGGAGAGTC CGCCTCCCAG CTGCTGGACG CGGAGACAGC CGAGAGGCTC 
CGGACCGAGA AGGAAATGAA AGAGCTACAG ACCCAGTACG ATGCCCTGAA GAAGCAGATG 
GAGGCGATGG ACATGGAAGT GATGGAGGCC CGGCTCATTC GGGCAGCCGA GATCAACGGG 
GAGGTGGATG ACGATGACGC AGGGGGAGAG TGGCGGCTGA AGTACGAGCG AGCTGTTCGG 
GAGGTGGACT TCACCAAGAA GCGGCTTCAG CAGGAGCTGG AAGACAAGAT GGAGGTGGAG 
CAGCAGAACA GGAGGCAGCT GGAGAGGCGG CTTGGGGACC TGCAAGCAGA TAGTGACGAG 
AGTCAGCGGG CACTGCAGCA GCTCAAGAAA AAGTGCCAAC GGCTCACAGC TGAGCTGCAG 
GACACCAAGC TGCACCTGGA GGGCCAGCAG GTCCGAAACC ATGAGCTGGA AAAGAAGCAG 
AGGAGGTTTG ACAGTGAGCT CTCCCAGGCA CATGAGGAGA CCCAGCGGGA GAAGCTGCAG 
AGGGAGAAGC TTCAGCGGGA GAAGGACATG CTCCTAGCTG AGGCCTTCAG CCTGAAGCAG 
CAGATGGAGG AAAAAGACTT GGATATCGCA GGGTTTACCC AGAAGGTTGT TTCCTTGGAG 
GCCGAGCTTC AGGACATTTC TTCTCAAGAG TCTAAGGATG AGGCTTCTCT GGCCAAGGTC 
AAGAAGCAGC TCCGGGACTT GGAGGCCAAG GTCAAGGATC AGGAAGAGGA GCTGGATGAA 
CAGGCTGGGA GCATACAGAT GCTGGAGCAG GCCAAGCTGC GTCTGGAGAT GGAGATGGAG 
CGGATGAGAC AGACCCATTC CAAGGAGATG GAGAGCCGGG ATGAGGAGGT GGAAGAGGCC 
CGGCAGTCAT GTCAGAAGAA GCTAAGGCAG ATGGAAGTTC AGCTGGAGGA GGAGTATGAA 
GACAAGCAGA AGGCGCTGCG GGAGAAACGG GAGCTGGAGA GCAAGCTCTC CACGCTCAGT 
GACCAGGTGA ACCAGCGGGA CTTTGAATCA GAGAAGCGGC TACGGAAAGA CCTGAAGCGC 
ACCAAAGCGC TGCTGGCAGA TGCTCAGATC ATGCTGGACC ACTTAAAGAA CAATGCCCCC 
AGCAAGAGGG AGATTGCCCA GCTGAAGAAC CAGCTGGAAG AGTCGGAATT CACCTGTGCA 
GCAGCTGTGA AGGCACGGAA AGCAATGGAG GTGGAGATGG AAGACCTGCA CCTGCAGATC 
GATGACATCG CCAAAGCCAA GACAGCGCTG GAGGAGCAAC TGAGTCGCCT TCAGCGTGAG 
AAAAATGAGA TTCAGAACCG GCTGGAAGAG GACCAGGAGG ACATGAATGA GCTGATGAAG 
AAGCACAAGG CGGCCGTGGC TCAGGCCTCC CGGGACATGG CACAGATGAA TGATCTCCAA 
GCTCAGCTCG AAGAGTCCAA CAAGGAGAAG CAGGAGCTAC AGGAGAAGCT ACAAGCTCTG 
CAGAGCCAGG TGGAGTTCCT AGAGCAGTCC ATGGTGGACA AGTCCCTTGT CAGCAGGCAG 
GAAGCGAAGA TCAGGGAGCT GGAGACACGC CTGGAGTTCG AAAAGACCCA AGTGAAACGT 
CTGGAGAGCA TGGCCAGTCG GCTCAAAGAA AACATGGAGA AGCTGACTGA GGAACGGGAC 
CAGCGCGCTG CAGCTGAGAA CCGTGAGAAG GAGCAGAACA AGAGGCTCCA GCGACAGCTC 
CGTGACACCA AGGAGGAGAT GAGCGAGCTT GCCAGGAAGG AAGCTGAGGC TAGTCGCAAG 
AAGCACGAAC TGGAGATGGA CTTGGAGAGT CTGGAAGCCG CTAACCAAAG CCTGCAAGCT 
GACCTAAAGC TGGCGTTCAA ACGCATTGGG GACTTGCAAG CCGCCATTGA GGATGAGATG 
GAGAGTGATG AGAATGAGGA CCTTATCAAC AGTTTGCAGG ATATGGTGAC AAAATATCAG 
AAAAGAAAGA ATAAACTTGA GGGCGACTCA GACGTGGACT CAGAGCTGGA GGACCGGGTC 
GACGGTGTCA AGTCCTGGTT GTCAAAGAAC AAGGGACCCT CTAAGGCACC TTCCGACGAT 
GGCAGCTTAA AGAGTTCCAG CCCAACCAGC CACTGGAAGT CCCTCGCCCC CGACCTGTCG 
GATGATGAGC ACGATCCTGT GGACAGCATC TCCAGACCCC GGTTCTCCCA CAACTATCTG 
AGTGACAGTG ACACAGAGGC CAAGCTGACA GAGACCAACG CATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001165608.1
CDS	171..6335
Translation	MFNLMKKDKDKDGGRKEKKEKKEKKERMSAAELRSLEEMSMRRGFFNLNRSSKRESKTRLEISNPIPIKVASGSDLHLTDIDSDSNRGSIILDSGHLSTASSSDDLKGEEGSFRGSVLQRAAKFGSLAKQNSQMIVKRFSFSQRSRDESASETSTPSEHSAAPSPQVEVRTLEGQLMQHSGLGIPRPGPRSRVPELVTKRFPADLRLPALVPPPPPALRELELQRRPTGDFGFSLRRTTMLDRAPEGQAYRRVVHFAEPGAGTKDLALGLVPGDRLVEINGQNVENKSRDEIVEMIRQSGDSVRLKVQPIPELSELSRSWLRTGEGHRREPTDAKTEEQIAAEEAWYETEKVWLVHRDGFSLASQLKSEELSLPEGKVRVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESSVLHTLRQRYGASLLHTYAGPSLLVLSPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSIVLLGSSGSGKTTSSQHLVQYLATIAGTSGNKVFSVEKWQALATLLEAFGNSPTIMNGSATRFSQILSLDFDQAGQVASASVQTMLLEKLRVARRPASEATFNVFYYLLACGDSTLRTELHLNHLAENNVFGIVPLSKPEEKQRAAQQFSKLQTAMKVLAISPEEQKACWLILASIYHLGAAGATKEAAEGGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQLKGGTLQRSTSFRQGPEESGLGEGTGTKLSALECLEGMASGLYSELFTLLISLVNRALKSSQHSLCSMMIVDTPGFQNPEWGGSARGASFEELCHNYAQDRLQKLFHERTFLQELERYKEDNIELAFDDLEPVTDDSVAAVDQASHQSLVRSLAHADEARGLLWLLEEEALVPGATEDTLLDRLFSYYGPQEGDKKGQSPLLRSSKPRHFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLFLGRAGTATVLSGSIAGLEGGSQLALRRATSMRKTFTTGMAAVKKKSLCIQIKLQVDALIDTIKRSKMHFVHCFLPVAEGWPGEPRSASSRRVSSSSELDLPPGDPCEAGLLQLDVSLLRAQLRGSRLLDAIRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYIVVDEKRAVEELLESLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEETSRHLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIQVQLSEEQIRNKDEEIQQLRNKLEKVEKERNELRLNSDRLETRISELTSELTDERNTGESASQLLDAETAERLRTEKEMKELQTQYDALKKQMEAMDMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQELEDKMEVEQQNRRQLERRLGDLQADSDESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEETQREKLQREKLQREKDMLLAEAFSLKQQMEEKDLDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGSIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLRQMEVQLEEEYEDKQKALREKRELESKLSTLSDQVNQRDFESEKRLRKDLKRTKALLADAQIMLDHLKNNAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEMEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDMAQMNDLQAQLEESNKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFEKTQVKRLESMASRLKENMEKLTEERDQRAAAENREKEQNKRLQRQLRDTKEEMSELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSLQDMVTKYQKRKNKLEGDSDVDSELEDRVDGVKSWLSKNKGPSKAPSDDGSLKSSSPTSHWKSLAPDLSDDEHDPVDSISRPRFSHNYLSDSDTEAKLTETNA

Target ORF information:

RefSeq Version	NM_001172137.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus myosin XVIIIa (Myo18a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001172137.1

ORF Insert Sequence:

ATGTTTAACC TCATGAAGAA AGACAAGGAC AAAGATGGCG GGCGGAAGGA GAAGAAGGAG 
AAAAAGGAGA AGAAGGAGAG GATGTCTGCG GCAGAACTGC GGAGCCTGGA AGAGATGAGC 
ATGCGCCGTG GCTTTTTCAA CTTGAACCGG TCCTCCAAGC GGGAATCCAA GACGCGCCTG 
GAAATCTCCA ACCCCATCCC TATCAAGGTG GCCAGTGGCT CTGACCTGCA CCTAACCGAC 
ATTGACTCTG ACAGCAATAG GGGTAGCATC ATCCTGGATT CAGGCCACCT AAGCACAGCC 
AGCTCCAGTG ATGACCTCAA GGGTGAAGAA GGCAGCTTCC GGGGTTCTGT GCTGCAGCGG 
GCAGCTAAGT TCGGTTCACT AGCCAAGCAG AACTCTCAGA TGATTGTCAA ACGTTTTTCC 
TTTTCTCAAC GGAGCCGGGA TGAGAGTGCC TCAGAGACCT CAACCCCCTC AGAGCACTCT 
GCAGCCCCAT CACCTCAGGT AGAGGTGAGG ACGCTTGAGG GACAGCTAAT GCAGCACTCT 
GGGCTAGGCA TCCCTCGACC AGGACCCAGG TCTCGAGTCC CTGAGCTGGT GACTAAAAGA 
TTCCCAGCTG ACTTACGTCT CCCGGCTCTG GTGCCCCCAC CACCTCCTGC TCTCCGGGAG 
CTGGAGTTAC AACGACGACC CACAGGAGAC TTTGGCTTCT CACTGCGGCG CACAACCATG 
CTGGACCGGG CCCCTGAGGG TCAGGCCTAT CGACGTGTGG TTCACTTTGC TGAGCCAGGG 
GCAGGCACCA AGGACCTGGC CTTGGGGCTG GTGCCAGGAG ACCGACTGGT GGAGATTAAT 
GGACAGAATG TGGAGAATAA GTCCAGGGAT GAAATTGTGG AGATGATCCG GCAGTCTGGG 
GACAGTGTGC GGCTCAAGGT ACAGCCCATC CCAGAGCTTA GCGAGCTGAG CCGGAGCTGG 
CTTCGGACTG GCGAGGGACA CCGCAGGGAG CCGACTGATG CCAAGACAGA AGAGCAGATT 
GCCGCTGAAG AGGCCTGGTA TGAGACGGAG AAGGTGTGGC TGGTCCATAG AGATGGATTC 
TCCTTAGCCA GCCAGCTCAA GTCGGAGGAG CTCAGCCTAC CCGAGGGGAA GGTGCGCGTG 
AAGCTAGACC ACGATGGAGC CATCCTGGAT GTGGATGAAG ATGACGTAGA GAAGGCTAAC 
GCTCCCTCAT GTGACCGACT AGAAGATCTG GCCTCCTTGG TGTACCTCAA CGAGTCTAGC 
GTCCTGCATA CACTGCGCCA GCGCTATGGG GCCAGCCTGC TACACACCTA TGCCGGCCCT 
AGCCTGCTTG TCCTTAGCCC CCGAGGGGCT CCTGCTGTGT ATTCAGAGAA GGTGATGCAC 
ATGTTCAAGG GGTGTCGGCG GGAGGACATG GCACCCCACA TCTATGCTGT AGCCCAGACT 
GCATATAGGG CCATGTTGAT GAGTCGTCAG GACCAGTCCA TCGTCCTTCT GGGCAGTAGT 
GGCAGTGGCA AGACCACCAG CTCTCAGCAT CTGGTGCAGT ATCTGGCTAC CATTGCCGGC 
ACCAGCGGGA ACAAGGTGTT CTCAGTGGAG AAGTGGCAGG CTCTGGCCAC CCTCCTGGAA 
GCCTTTGGGA ACAGCCCTAC CATCATGAAC GGCAGTGCCA CCCGCTTCTC CCAGATCCTC 
TCCCTGGACT TTGACCAAGC TGGCCAGGTG GCTTCAGCCT CCGTCCAGAC CATGCTCCTG 
GAGAAGCTGC GTGTGGCCCG ACGCCCAGCC AGCGAGGCCA CTTTCAATGT CTTCTACTAC 
TTGCTGGCCT GTGGGGACAG CACCCTCAGG ACAGAGCTCC ACCTGAACCA CTTGGCAGAG 
AACAATGTGT TTGGAATTGT GCCATTGTCC AAGCCTGAGG AGAAGCAGAG GGCTGCTCAG 
CAGTTCAGTA AGCTACAGAC GGCCATGAAG GTGCTGGCCA TCTCCCCTGA GGAACAGAAG 
GCCTGCTGGC TCATCCTGGC TTCCATCTAC CACTTGGGGG CTGCTGGAGC TACCAAAGAA 
GCTGCTGAAG GTGGACGTAA GCAATTTGCC CGTCATGAAT GGGCCCAGAA GGCCGCATAC 
CTGCTAGGCT GCAGCTTGGA AGAGCTGTCC TCAGCGATCT TCAAGCACCA GCTCAAAGGC 
GGCACCCTGC AACGGTCTAC CTCCTTCCGT CAGGGCCCTG AGGAGAGCGG CCTGGGAGAG 
GGTACAGGCA CCAAGCTGAG TGCTCTGGAG TGCTTAGAGG GTATGGCGTC TGGCCTCTAC 
AGCGAGCTCT TTACTCTCCT CATCTCCCTG GTAAACAGGG CTCTCAAGTC CAGCCAGCAC 
TCACTGTGTT CCATGATGAT TGTGGATACA CCAGGCTTCC AGAACCCTGA ATGGGGTGGC 
TCAGCCCGTG GCGCCTCCTT CGAGGAGCTG TGCCACAACT ATGCCCAGGA CAGGTTGCAG 
AAGCTGTTCC ATGAGCGCAC CTTCCTCCAG GAGTTGGAAA GGTACAAGGA GGACAACATC 
GAACTGGCGT TTGATGACTT GGAGCCAGTC ACAGATGACT CAGTGGCTGC TGTGGACCAG 
GCCTCCCACC AGTCCCTGGT TCGCTCACTG GCCCATGCCG ATGAGGCAAG AGGACTACTG 
TGGCTCCTAG AAGAGGAGGC TCTGGTGCCA GGTGCGACTG AGGATACCCT CCTGGACCGT 
CTTTTCTCCT ATTATGGCCC CCAGGAAGGT GACAAAAAAG GTCAGAGTCC TCTTCTGCGC 
AGTAGCAAAC CACGGCACTT TCTCCTGGGC CACAGCCATG GTACCAACTG GGTGGAGTAC 
AATGTGACCG GCTGGCTGAA CTACACCAAG CAGAACCCAG CCACCCAGAA TGCACCCCGG 
CTCCTGCAGG ACTCCCAGAA AAAGATCATC AGCAACCTGT TTCTGGGCCG GGCAGGCACT 
GCCACAGTGC TCTCGGGCTC AATTGCAGGC CTGGAAGGTG GCTCCCAGCT GGCCTTGCGC 
CGGGCAACTA GCATGAGGAA AACCTTTACC ACTGGCATGG CAGCTGTCAA GAAGAAGTCA 
CTGTGCATAC AGATCAAGCT GCAAGTGGAT GCCCTCATCG ATACCATCAA GAGGTCCAAG 
ATGCATTTCG TGCACTGCTT CCTTCCTGTG GCCGAGGGCT GGCCTGGGGA GCCCCGATCT 
GCTTCTTCTC GCCGAGTTAG TAGCAGCAGT GAGCTGGACC TGCCTCCGGG AGACCCCTGC 
GAGGCTGGGC TGCTACAACT GGATGTGTCC CTGCTCCGTG CCCAGCTTCG GGGATCCCGC 
CTGCTTGATG CAATACGCAT GTACCGCCAA GGTTACCCAG ACCACATGGT GTTTTCTGAG 
TTCCGTAGGC GCTTTGATGT CCTGGCCCCA CACCTGACCA AGAAACATGG GCGTAACTAC 
ATCGTGGTGG ATGAGAAGCG GGCTGTGGAG GAGCTGCTGG AGTCCCTAGA CCTGGAAAAG 
AGCAGCTGCT GCATGGGCCT GAGTCGGGTA TTCTTCCGGG CAGGCACGTT GGCACGGCTG 
GAAGAGCAAC GAGACGAGGA AACCAGCAGA CACCTGACCC TGTTCCAGGC AGCCTGCAGG 
GGCTACCTTG CCCGCCAGCA CTTCAAGAAG AGAAAGATCC AGGACCTGGC CATTCGCTGT 
GTGCAGAAGA ACATCAAGAA GAACAAGGGG GTGAAGGACT GGCCCTGGTG GAAGCTCTTC 
ACCACTGTGC GGCCCCTCAT CCAAGTTCAG CTGTCTGAGG AGCAGATCCG AAACAAAGAC 
GAGGAGATCC AGCAGCTGCG AAACAAGCTT GAGAAGGTGG AGAAAGAGAG GAATGAGCTT 
CGGCTCAACA GTGACCGGCT GGAGACCCGG ATCTCAGAGC TGACATCGGA GCTGACTGAT 
GAACGCAACA CAGGAGAGTC CGCCTCCCAG CTGCTGGACG CGGAGACAGC CGAGAGGCTC 
CGGACCGAGA AGGAAATGAA AGAGCTACAG ACCCAGTACG ATGCCCTGAA GAAGCAGATG 
GAGGCGATGG ACATGGAAGT GATGGAGGCC CGGCTCATTC GGGCAGCCGA GATCAACGGG 
GAGGTGGATG ACGATGACGC AGGGGGAGAG TGGCGGCTGA AGTACGAGCG AGCTGTTCGG 
GAGGTGGACT TCACCAAGAA GCGGCTTCAG CAGGAGCTGG AAGACAAGAT GGAGGTGGAG 
CAGCAGAACA GGAGGCAGCT GGAGAGGCGG CTTGGGGACC TGCAAGCAGA TAGTGACGAG 
AGTCAGCGGG CACTGCAGCA GCTCAAGAAA AAGTGCCAAC GGCTCACAGC TGAGCTGCAG 
GACACCAAGC TGCACCTGGA GGGCCAGCAG GTCCGAAACC ATGAGCTGGA AAAGAAGCAG 
AGGAGGTTTG ACAGTGAGCT CTCCCAGGCA CATGAGGAGA CCCAGCGGGA GAAGCTGCAG 
AGGGAGAAGC TTCAGCGGGA GAAGGACATG CTCCTAGCTG AGGCCTTCAG CCTGAAGCAG 
CAGATGGAGG AAAAAGACTT GGATATCGCA GGGTTTACCC AGAAGGTTGT TTCCTTGGAG 
GCCGAGCTTC AGGACATTTC TTCTCAAGAG TCTAAGGATG AGGCTTCTCT GGCCAAGGTC 
AAGAAGCAGC TCCGGGACTT GGAGGCCAAG GTCAAGGATC AGGAAGAGGA GCTGGATGAA 
CAGGCTGGGA GCATACAGAT GCTGGAGCAG GCCAAGCTGC GTCTGGAGAT GGAGATGGAG 
CGGATGAGAC AGACCCATTC CAAGGAGATG GAGAGCCGGG ATGAGGAGGT GGAAGAGGCC 
CGGCAGTCAT GTCAGAAGAA GCTAAGGCAG ATGGAAGTTC AGCTGGAGGA GGAGTATGAA 
GACAAGCAGA AGGCGCTGCG GGAGAAACGG GAGCTGGAGA GCAAGCTCTC CACGCTCAGT 
GACCAGGTGA ACCAGCGGGA CTTTGAATCA GAGAAGCGGC TACGGAAAGA CCTGAAGCGC 
ACCAAAGCGC TGCTGGCAGA TGCTCAGATC ATGCTGGACC ACTTAAAGAA CAATGCCCCC 
AGCAAGAGGG AGATTGCCCA GCTGAAGAAC CAGCTGGAAG AGTCGGAATT CACCTGTGCA 
GCAGCTGTGA AGGCACGGAA AGCAATGGAG GTGGAGATGG AAGACCTGCA CCTGCAGATC 
GATGACATCG CCAAAGCCAA GACAGCGCTG GAGGAGCAAC TGAGTCGCCT TCAGCGTGAG 
AAAAATGAGA TTCAGAACCG GCTGGAAGAG GACCAGGAGG ACATGAATGA GCTGATGAAG 
AAGCACAAGG CGGCCGTGGC TCAGGCCTCC CGGGACATGG CACAGATGAA TGATCTCCAA 
GCTCAGCTCG AAGAGTCCAA CAAGGAGAAG CAGGAGCTAC AGGAGAAGCT ACAAGCTCTG 
CAGAGCCAGG TGGAGTTCCT AGAGCAGTCC ATGGTGGACA AGTCCCTTGT CAGCAGGCAG 
GAAGCGAAGA TCAGGGAGCT GGAGACACGC CTGGAGTTCG AAAAGACCCA AGTGAAACGT 
CTGGAGAGCA TGGCCAGTCG GCTCAAAGAA AACATGGAGA AGCTGACTGA GGAACGGGAC 
CAGCGCGCTG CAGCTGAGAA CCGTGAGAAG GAGCAGAACA AGAGGCTCCA GCGACAGCTC 
CGTGACACCA AGGAGGAGAT GAGCGAGCTT GCCAGGAAGG AAGCTGAGGC TAGTCGCAAG 
AAGCACGAAC TGGAGATGGA CTTGGAGAGT CTGGAAGCCG CTAACCAAAG CCTGCAAGCT 
GACCTAAAGC TGGCGTTCAA ACGCATTGGG GACTTGCAAG CCGCCATTGA GGATGAGATG 
GAGAGTGATG AGAATGAGGA CCTTATCAAC AGTTTGCAGG ATATGGTGAC AAAATATCAG 
AAAAGAAAGA ATAAACTTGA GGGCGACTCA GACGTGGACT CAGAGCTGGA GGACCGGGTC 
GACGGTGTCA AGTCCTGGTT GTCAAAGAAC AAGGGACCCT CTAAGGCACC TTCCGACGAT 
GGCAGCTTAA AGAGTTCCAG CCCAACCAGC CACTGGAAGT CCCTCGCCCC CGACCTGTCG 
GATGATGAGC ACGATCCTGT GGACAGCATC TCCAGACCCC GGTTCTCCCA CAACTATCTG 
AGTGACAGTG ACACAGAGGC CAAGCTGACA GAGACCAACG CATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

SP-R210 (Myo18A) Isoforms as Intrinsic Modulators of Macrophage Priming and Activation.
PloS one10(5)e0126576(2015)
Yang L,Carrillo M,Wu YM,DiAngelo SL,Silveyra P,Umstead TM,Halstead ES,Davies ML,Hu S,Floros J,McCormack FX,Christensen ND,Chroneos ZC

DNA damage triggers Golgi dispersal via DNA-PK and GOLPH3.
Cell156(3)413-27(2014 Jan)
Farber-Katz SE,Dippold HC,Buschman MD,Peterman MC,Xing M,Noakes CJ,Tat J,Ng MM,Rahajeng J,Cowan DM,Fuchs GJ,Zhou H,Field SJ

Functional characterization of human myosin-18A and its interaction with F-actin and GOLPH3.
The Journal of biological chemistry288(42)30029-41(2013 Oct)
Taft MH,Behrmann E,Munske-Weidemann LC,Thiel C,Raunser S,Manstein DJ

GOLPH3L antagonizes GOLPH3 to determine Golgi morphology.
Molecular biology of the cell24(6)796-808(2013 Mar)
Ng MM,Dippold HC,Buschman MD,Noakes CJ,Field SJ

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Molecular cell46(5)674-90(2012 Jun)
Baltz AG,Munschauer M,Schwanh?usser B,Vasile A,Murakawa Y,Schueler M,Youngs N,Penfold-Brown D,Drew K,Milek M,Wyler E,Bonneau R,Selbach M,Dieterich C,Landthaler M

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Myo18a cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

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