Npas2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Npas2
Entrez Gene ID	316351
Full Name	neuronal PAS domain protein 2
General protein information	Preferred Names neuronal PAS domain protein 2 Names neuronal PAS domain-containing protein 2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 9 Map Location: 9q22
Summary	The protein encoded by this gene is a member of the basic helix-loop-helix (bHLH)-PAS family of transcription factors. A similar mouse protein may play a regulatory role in the acquisition of specific types of memory. It also may function as a part of a molecular clock operative in the mammalian forebrain. [provided by RefSeq, Feb 2014].

mRNA and Protein(s)

mRNA	Protein	Name
XM_008767033.2	XP_008765255.1	neuronal PAS domain-containing protein 2 isoform X1
NM_001108214.2	NP_001101684.2	neuronal PAS domain-containing protein 2
XM_008767031.2	XP_008765253.1	neuronal PAS domain-containing protein 2 isoform X1
XM_008767032.2	XP_008765254.1	neuronal PAS domain-containing protein 2 isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	NPAS2	NP_002509.2
	NPAS2	XP_001105763.2
Canis lupus familiaris (dog)	NPAS2	XP_005626061.1
Xenopus tropicalis (tropical clawed frog)	npas2	XP_004911838.1
Pan troglodytes (chimpanzee)	NPAS2	XP_003309214.1
Mus musculus (house mouse)	Npas2	NP_032745.2
Rattus norvegicus (Norway rat)	Npas2	NP_001101684.2
Bos taurus (cattle)	NPAS2	NP_001077232.1
Gallus gallus (chicken)	NPAS2	NP_001025713.1

Gene Ontology
Bibliography

Related articles in PubMed

Prefrontal cortex and dorsomedial hypothalamus mediate food reward-induced effects via npas2 and egr1 expression in rat.
Herichov? I, Has?kov? K, Luk??ov? D, Mravec B, Horv?thov? ?, Kavick? D
Physiological research66(Supplementum 4)S501-S510(2017 Dec)

NPAS2 Regulation of Anxiety-Like Behavior and GABAA Receptors.
Ozburn AR, Kern J, Parekh PK, Logan RW, Liu Z, Falcon E, Becker-Krail D, Purohit K, Edgar NM, Huang Y, McClung CA
Frontiers in molecular neuroscience10360(2017)

Small heterodimer partner/neuronal PAS domain protein 2 axis regulates the oscillation of liver lipid metabolism.
Lee SM, Zhang Y, Tsuchiya H, Smalling R, Jetten AM, Wang L
Hepatology (Baltimore, Md.)61(2)497-505(2015 Feb)

Circadian rhythm of contrast sensitivity is regulated by a dopamine-neuronal PAS-domain protein 2-adenylyl cyclase 1 signaling pathway in retinal ganglion cells.
Hwang CK, Chaurasia SS, Jackson CR, Chan GC, Storm DR, Iuvone PM
The Journal of neuroscience : the official journal of the Society for Neuroscience33(38)14989-97(2013 Sep)

Effect of streptozotocin-induced diabetes on clock gene expression in tissues inside and outside the blood-brain barrier in rat.
?olt?sov? D, Mono??kov? J, Koy?ov? L, Vesel? A, Mravec B, Herichov? I
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association121(8)466-74(2013 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Possible role of npas2 in locomotor activity regulation in diabetic animals. The most pronounced changes were observed in the frontal cortex, which displayed up-regulation of npas2 expression.
Title: Effect of streptozotocin-induced diabetes on clock gene expression in tissues inside and outside the blood-brain barrier in rat.

The following Npas2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Npas2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa12717	NM_001108214.2 Latest version!	Rattus norvegicus neuronal PAS domain protein 2 (Npas2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
ORa12717	XM_008767031.2 Latest version!	Rattus norvegicus neuronal PAS domain protein 2 (Npas2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
ORa12717	XM_008767032.2 Latest version!	Rattus norvegicus neuronal PAS domain protein 2 (Npas2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
ORa12717	XM_008767033.2 Latest version!	Rattus norvegicus neuronal PAS domain protein 2 (Npas2), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Npas2 ( NM_001108214.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001101684.2 Rattus norvegicus neuronal PAS domain protein 2 (Npas2), mRNA.

Price & Availability↑

CloneID	ORa12717
Clone ID Related Accession (Same CDS sequence)	XM_008767033.2 , NM_001108214.2 , XM_008767031.2 , XM_008767032.2
Accession Version	NM_001108214.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2451bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-18
Organism	Rattus norvegicus(Norway rat)
Product	neuronal PAS domain-containing protein 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07067441.1, AABR07067442.1, AABR07067443.1 and AABR07067444.1. On Oct 29, 2008 this sequence version replaced NM_001108214.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. COMPLETENESS: complete on the 3' end.

ATGGACGAAG ATGAGAAGGA TAGAGCAAAG AGAGCCTCTC GAAACAAGTC TGAGAAGAAG 
CGTCGGGACC AGTTCAATGT TCTCATCAAA GAGCTCAGCT CCATGCTCCC AGGCAACACT 
CGGAAACTGG ACAAAACAAC TGTGCTGGAG AAGGTCATCG GATTTCTGCA GAAACACAAT 
GAAGTCTCAG CACAAACAGA AATCTGTGAC ATCCAGCAGG ACTGGAAGCC TTCATTCCTC 
AGTAACGAAG AATTCACCCA GCTGATGTTG GAGGCGTTAG ATGGCTTCGT CATTGTTGTG 
ACAACGGACG GCAGCATCAT CTATGTGTCC GACAGCATCA CGCCTCTCCT CGGACATTTA 
CCGTCGGATG TCATGGATCA GAACTTGTTA AATTTCCTTC CAGAACAAGA ACATTCCGAA 
GTTTATAAAA TCCTTTCCTC CCATATGCTT GTGACGGATT CCCCCTCCCC AGAATTCCTA 
AAATCTGACA ACGATTTAGA GTTTTATTGT CATCTTCTGA GAGGCAGCTT GAACCCAAAG 
GAATTTCCAA CTTACGAATA CATAAAATTT GTAGGAAATT TTCGCTCTTA CAACAATGTG 
CCTAGCCCCT CCTGTAATGG CTTTGACAAC ACCCTTTCAA GACCCTGCCG CGTGCCCCTG 
GGGAAGGAGG TCTGCTTCAT CGCCACGGTG CGCCTGGCAA CACCACAGTT CTTAAAGGAA 
ATGTGTGTAG CTGACGAACC TTTAGAGGAA TTCACTTCGA GGCATAGCTT GGAATGGAAA 
TTTTTATTTC TGGATCACAG AGCCCCTCCA ATCATAGGAT ACCTGCCCTT TGAAGTACTT 
GGCACGTCAG GCTATGACTA CTACCACATT GATGACCTGG AGCTCCTGGC CAGGTGCCAC 
CAGCACTTGA TGCAGTTTGG CAAAGGGAAG TCGTGTTGTT ACCGGTTTCT AACCAAAGGA 
CAGCAGTGGA TTTGGTTGCA AACCCACTAC TACATCACCT ACCACCAGTG GAACTCCAAG 
CCCGAGTTCA TCGTGTGCAC ACACTCGGTG GTCAGTTACG CAGATGTCCG AGTGGAAAGG 
AGACAGGAGC TGGCTCTGGA AGATCCACCC ACAGAAGCCA TGCACCCCTC TGCACTGAAG 
GAAAAGGACT CAAGCCTAGA GCCTCAGCCG CACTTTAATG CACTTGACAT GGGTGCCTCA 
GGTCTTACCA GCAGTCCTTC GCCATCAGCA TCCTCGAGGA GTTCCCACAA GTCCTCACAC 
ACAGCCATGT CAGAACCCAC CTCCACTCCA ACCAAGCTGA TGGCTGAGAA CAGCACCACA 
GCTTTGCCAA GATCAGCCAC CCTACCCCAG GAGTTACCAG TGCAGGGGCT CAGCCAGGCA 
GCCACAATGC CAGCTCCTCT GCTTTCCTCA TCATCCTGTG ACCTTGCCAA GCAGCTCCTG 
CCTCAGTCCC TGCCTCAGAC GGTCCTGCAG AGTCCACCTG CTCCAGTGAC ACAGTTTTCA 
GCACAATTTA GCATGTTCCA GACCATAAAA GACCAGTTGG AGCAGAGGAC ACGGATCCTG 
CAGGCCAACA TTCGGTGGCA GCAGGAAGAG CTTCACAAGA TCCAGGAACA ACTCTGCCTG 
GTCCAGGACT CCAACGTCCA GATGTTTCTA CAGCAGCCAG CGGTGTCTCT GAGCTTCAGC 
GGTGCCCAGA GACCGGCAGC TCAGCAGCCA CTGCAACAAA GGCCATCTGC ACCGTCTCAG 
CCCCCGCTTG TGGTCAACAC TCCACTGCCG GGGCAGATCA CATCCACCCA AGTCACAAAC 
CAGCACCTGC TCAGAGAATC GAATGTGATG TCCGCCCAGG GTCCAAAACC AATAAGAAGC 
TCCCAGTTGC TGCCTGCCAG CAGCCGTTCA CTGAGCAGCC TGCCGTCCCA GTTCAGCAGC 
ACAGCGTCCG TGCTCCCACC AGGCCTGAGC CTCACCACTG TCGCTCCCAC CCCTCAGGAC 
ACCAGCCAGT GCCAGCCCAG CCCTGACTTC GGCCATGATC GGCAGCTCAG GCTGTTGCTG 
AGCCAACCCA TCCAGCCTAT GATGCCTGGG TCTTGTGATG CCAGGCAGCC CTCAGAAGTC 
AGCAGGACTG GACGGCAAGT CAAATATGCA CAGAGCCAAG TGACGTTTCC AAGTCCTGAC 
TCCCACCCCA CCAGCAGCAG CGCCCCCACC CCGGTCCTGT TGATGGGGCA GGCCGTGCTC 
CATCCCGGCT TCCCCGCATC CCAGCCATCA CCCCTGCAAC CAACACAGGT ACAACAGCAG 
CCACCACCCT ATCTACAGGC ACCAACATCT CTGCACAGTG AACAGCCGGA CTCGCTCCTT 
CTCTCCACCT TCTCCCAGCA GCCAGCACCT CTGGGCTATG CAGCCACACA GCCTACACAG 
CCGCAACCCC CACGCCCTTC CCGCAGGGTC AGCCGGCTGT CAGAGTCCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001101684.2
CDS	549..2999
Translation	MDEDEKDRAKRASRNKSEKKRRDQFNVLIKELSSMLPGNTRKLDKTTVLEKVIGFLQKHNEVSAQTEICDIQQDWKPSFLSNEEFTQLMLEALDGFVIVVTTDGSIIYVSDSITPLLGHLPSDVMDQNLLNFLPEQEHSEVYKILSSHMLVTDSPSPEFLKSDNDLEFYCHLLRGSLNPKEFPTYEYIKFVGNFRSYNNVPSPSCNGFDNTLSRPCRVPLGKEVCFIATVRLATPQFLKEMCVADEPLEEFTSRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYDYYHIDDLELLARCHQHLMQFGKGKSCCYRFLTKGQQWIWLQTHYYITYHQWNSKPEFIVCTHSVVSYADVRVERRQELALEDPPTEAMHPSALKEKDSSLEPQPHFNALDMGASGLTSSPSPSASSRSSHKSSHTAMSEPTSTPTKLMAENSTTALPRSATLPQELPVQGLSQAATMPAPLLSSSSCDLAKQLLPQSLPQTVLQSPPAPVTQFSAQFSMFQTIKDQLEQRTRILQANIRWQQEELHKIQEQLCLVQDSNVQMFLQQPAVSLSFSGAQRPAAQQPLQQRPSAPSQPPLVVNTPLPGQITSTQVTNQHLLRESNVMSAQGPKPIRSSQLLPASSRSLSSLPSQFSSTASVLPPGLSLTTVAPTPQDTSQCQPSPDFGHDRQLRLLLSQPIQPMMPGSCDARQPSEVSRTGRQVKYAQSQVTFPSPDSHPTSSSAPTPVLLMGQAVLHPGFPASQPSPLQPTQVQQQPPPYLQAPTSLHSEQPDSLLLSTFSQQPAPLGYAATQPTQPQPPRPSRRVSRLSES

Target ORF information:

RefSeq Version	NM_001108214.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus neuronal PAS domain protein 2 (Npas2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001108214.2

ORF Insert Sequence:

ATGGACGAAG ATGAGAAGGA TAGAGCAAAG AGAGCCTCTC GAAACAAGTC TGAGAAGAAG 
CGTCGGGACC AGTTCAATGT TCTCATCAAA GAGCTCAGCT CCATGCTCCC AGGCAACACT 
CGGAAACTGG ACAAAACAAC TGTGCTGGAG AAGGTCATCG GATTTCTGCA GAAACACAAT 
GAAGTCTCAG CACAAACAGA AATCTGTGAC ATCCAGCAGG ACTGGAAGCC TTCATTCCTC 
AGTAACGAAG AATTCACCCA GCTGATGTTG GAGGCGTTAG ATGGCTTCGT CATTGTTGTG 
ACAACGGACG GCAGCATCAT CTATGTGTCC GACAGCATCA CGCCTCTCCT CGGACATTTA 
CCGTCGGATG TCATGGATCA GAACTTGTTA AATTTCCTTC CAGAACAAGA ACATTCCGAA 
GTTTATAAAA TCCTTTCCTC CCATATGCTT GTGACGGATT CCCCCTCCCC AGAATTCCTA 
AAATCTGACA ACGATTTAGA GTTTTATTGT CATCTTCTGA GAGGCAGCTT GAACCCAAAG 
GAATTTCCAA CTTACGAATA CATAAAATTT GTAGGAAATT TTCGCTCTTA CAACAATGTG 
CCTAGCCCCT CCTGTAATGG CTTTGACAAC ACCCTTTCAA GACCCTGCCG CGTGCCCCTG 
GGGAAGGAGG TCTGCTTCAT CGCCACGGTG CGCCTGGCAA CACCACAGTT CTTAAAGGAA 
ATGTGTGTAG CTGACGAACC TTTAGAGGAA TTCACTTCGA GGCATAGCTT GGAATGGAAA 
TTTTTATTTC TGGATCACAG AGCCCCTCCA ATCATAGGAT ACCTGCCCTT TGAAGTACTT 
GGCACGTCAG GCTATGACTA CTACCACATT GATGACCTGG AGCTCCTGGC CAGGTGCCAC 
CAGCACTTGA TGCAGTTTGG CAAAGGGAAG TCGTGTTGTT ACCGGTTTCT AACCAAAGGA 
CAGCAGTGGA TTTGGTTGCA AACCCACTAC TACATCACCT ACCACCAGTG GAACTCCAAG 
CCCGAGTTCA TCGTGTGCAC ACACTCGGTG GTCAGTTACG CAGATGTCCG AGTGGAAAGG 
AGACAGGAGC TGGCTCTGGA AGATCCACCC ACAGAAGCCA TGCACCCCTC TGCACTGAAG 
GAAAAGGACT CAAGCCTAGA GCCTCAGCCG CACTTTAATG CACTTGACAT GGGTGCCTCA 
GGTCTTACCA GCAGTCCTTC GCCATCAGCA TCCTCGAGGA GTTCCCACAA GTCCTCACAC 
ACAGCCATGT CAGAACCCAC CTCCACTCCA ACCAAGCTGA TGGCTGAGAA CAGCACCACA 
GCTTTGCCAA GATCAGCCAC CCTACCCCAG GAGTTACCAG TGCAGGGGCT CAGCCAGGCA 
GCCACAATGC CAGCTCCTCT GCTTTCCTCA TCATCCTGTG ACCTTGCCAA GCAGCTCCTG 
CCTCAGTCCC TGCCTCAGAC GGTCCTGCAG AGTCCACCTG CTCCAGTGAC ACAGTTTTCA 
GCACAATTTA GCATGTTCCA GACCATAAAA GACCAGTTGG AGCAGAGGAC ACGGATCCTG 
CAGGCCAACA TTCGGTGGCA GCAGGAAGAG CTTCACAAGA TCCAGGAACA ACTCTGCCTG 
GTCCAGGACT CCAACGTCCA GATGTTTCTA CAGCAGCCAG CGGTGTCTCT GAGCTTCAGC 
GGTGCCCAGA GACCGGCAGC TCAGCAGCCA CTGCAACAAA GGCCATCTGC ACCGTCTCAG 
CCCCCGCTTG TGGTCAACAC TCCACTGCCG GGGCAGATCA CATCCACCCA AGTCACAAAC 
CAGCACCTGC TCAGAGAATC GAATGTGATG TCCGCCCAGG GTCCAAAACC AATAAGAAGC 
TCCCAGTTGC TGCCTGCCAG CAGCCGTTCA CTGAGCAGCC TGCCGTCCCA GTTCAGCAGC 
ACAGCGTCCG TGCTCCCACC AGGCCTGAGC CTCACCACTG TCGCTCCCAC CCCTCAGGAC 
ACCAGCCAGT GCCAGCCCAG CCCTGACTTC GGCCATGATC GGCAGCTCAG GCTGTTGCTG 
AGCCAACCCA TCCAGCCTAT GATGCCTGGG TCTTGTGATG CCAGGCAGCC CTCAGAAGTC 
AGCAGGACTG GACGGCAAGT CAAATATGCA CAGAGCCAAG TGACGTTTCC AAGTCCTGAC 
TCCCACCCCA CCAGCAGCAG CGCCCCCACC CCGGTCCTGT TGATGGGGCA GGCCGTGCTC 
CATCCCGGCT TCCCCGCATC CCAGCCATCA CCCCTGCAAC CAACACAGGT ACAACAGCAG 
CCACCACCCT ATCTACAGGC ACCAACATCT CTGCACAGTG AACAGCCGGA CTCGCTCCTT 
CTCTCCACCT TCTCCCAGCA GCCAGCACCT CTGGGCTATG CAGCCACACA GCCTACACAG 
CCGCAACCCC CACGCCCTTC CCGCAGGGTC AGCCGGCTGT CAGAGTCCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Npas2 ( XM_008767033.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008765255.1 Rattus norvegicus neuronal PAS domain protein 2 (Npas2), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa12717
Clone ID Related Accession (Same CDS sequence)	XM_008767033.2 , NM_001108214.2 , XM_008767031.2 , XM_008767032.2
Accession Version	XM_008767033.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2451bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	neuronal PAS domain-containing protein 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005108.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008767033.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACGAAG ATGAGAAGGA TAGAGCAAAG AGAGCCTCTC GAAACAAGTC TGAGAAGAAG 
CGTCGGGACC AGTTCAATGT TCTCATCAAA GAGCTCAGCT CCATGCTCCC AGGCAACACT 
CGGAAACTGG ACAAAACAAC TGTGCTGGAG AAGGTCATCG GATTTCTGCA GAAACACAAT 
GAAGTCTCAG CACAAACAGA AATCTGTGAC ATCCAGCAGG ACTGGAAGCC TTCATTCCTC 
AGTAACGAAG AATTCACCCA GCTGATGTTG GAGGCGTTAG ATGGCTTCGT CATTGTTGTG 
ACAACGGACG GCAGCATCAT CTATGTGTCC GACAGCATCA CGCCTCTCCT CGGACATTTA 
CCGTCGGATG TCATGGATCA GAACTTGTTA AATTTCCTTC CAGAACAAGA ACATTCCGAA 
GTTTATAAAA TCCTTTCCTC CCATATGCTT GTGACGGATT CCCCCTCCCC AGAATTCCTA 
AAATCTGACA ACGATTTAGA GTTTTATTGT CATCTTCTGA GAGGCAGCTT GAACCCAAAG 
GAATTTCCAA CTTACGAATA CATAAAATTT GTAGGAAATT TTCGCTCTTA CAACAATGTG 
CCTAGCCCCT CCTGTAATGG CTTTGACAAC ACCCTTTCAA GACCCTGCCG CGTGCCCCTG 
GGGAAGGAGG TCTGCTTCAT CGCCACGGTG CGCCTGGCAA CACCACAGTT CTTAAAGGAA 
ATGTGTGTAG CTGACGAACC TTTAGAGGAA TTCACTTCGA GGCATAGCTT GGAATGGAAA 
TTTTTATTTC TGGATCACAG AGCCCCTCCA ATCATAGGAT ACCTGCCCTT TGAAGTACTT 
GGCACGTCAG GCTATGACTA CTACCACATT GATGACCTGG AGCTCCTGGC CAGGTGCCAC 
CAGCACTTGA TGCAGTTTGG CAAAGGGAAG TCGTGTTGTT ACCGGTTTCT AACCAAAGGA 
CAGCAGTGGA TTTGGTTGCA AACCCACTAC TACATCACCT ACCACCAGTG GAACTCCAAG 
CCCGAGTTCA TCGTGTGCAC ACACTCGGTG GTCAGTTACG CAGATGTCCG AGTGGAAAGG 
AGACAGGAGC TGGCTCTGGA AGATCCACCC ACAGAAGCCA TGCACCCCTC TGCACTGAAG 
GAAAAGGACT CAAGCCTAGA GCCTCAGCCG CACTTTAATG CACTTGACAT GGGTGCCTCA 
GGTCTTACCA GCAGTCCTTC GCCATCAGCA TCCTCGAGGA GTTCCCACAA GTCCTCACAC 
ACAGCCATGT CAGAACCCAC CTCCACTCCA ACCAAGCTGA TGGCTGAGAA CAGCACCACA 
GCTTTGCCAA GATCAGCCAC CCTACCCCAG GAGTTACCAG TGCAGGGGCT CAGCCAGGCA 
GCCACAATGC CAGCTCCTCT GCTTTCCTCA TCATCCTGTG ACCTTGCCAA GCAGCTCCTG 
CCTCAGTCCC TGCCTCAGAC GGTCCTGCAG AGTCCACCTG CTCCAGTGAC ACAGTTTTCA 
GCACAATTTA GCATGTTCCA GACCATAAAA GACCAGTTGG AGCAGAGGAC ACGGATCCTG 
CAGGCCAACA TTCGGTGGCA GCAGGAAGAG CTTCACAAGA TCCAGGAACA ACTCTGCCTG 
GTCCAGGACT CCAACGTCCA GATGTTTCTA CAGCAGCCAG CGGTGTCTCT GAGCTTCAGC 
GGTGCCCAGA GACCGGCAGC TCAGCAGCCA CTGCAACAAA GGCCATCTGC ACCGTCTCAG 
CCCCCGCTTG TGGTCAACAC TCCACTGCCG GGGCAGATCA CATCCACCCA AGTCACAAAC 
CAGCACCTGC TCAGAGAATC GAATGTGATG TCCGCCCAGG GTCCAAAACC AATAAGAAGC 
TCCCAGTTGC TGCCTGCCAG CAGCCGTTCA CTGAGCAGCC TGCCGTCCCA GTTCAGCAGC 
ACAGCGTCCG TGCTCCCACC AGGCCTGAGC CTCACCACTG TCGCTCCCAC CCCTCAGGAC 
ACCAGCCAGT GCCAGCCCAG CCCTGACTTC GGCCATGATC GGCAGCTCAG GCTGTTGCTG 
AGCCAACCCA TCCAGCCTAT GATGCCTGGG TCTTGTGATG CCAGGCAGCC CTCAGAAGTC 
AGCAGGACTG GACGGCAAGT CAAATATGCA CAGAGCCAAG TGACGTTTCC AAGTCCTGAC 
TCCCACCCCA CCAGCAGCAG CGCCCCCACC CCGGTCCTGT TGATGGGGCA GGCCGTGCTC 
CATCCCGGCT TCCCCGCATC CCAGCCATCA CCCCTGCAAC CAACACAGGT ACAACAGCAG 
CCACCACCCT ATCTACAGGC ACCAACATCT CTGCACAGTG AACAGCCGGA CTCGCTCCTT 
CTCTCCACCT TCTCCCAGCA GCCAGCACCT CTGGGCTATG CAGCCACACA GCCTACACAG 
CCGCAACCCC CACGCCCTTC CCGCAGGGTC AGCCGGCTGT CAGAGTCCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008765255.1
CDS	738..3188
Translation	MDEDEKDRAKRASRNKSEKKRRDQFNVLIKELSSMLPGNTRKLDKTTVLEKVIGFLQKHNEVSAQTEICDIQQDWKPSFLSNEEFTQLMLEALDGFVIVVTTDGSIIYVSDSITPLLGHLPSDVMDQNLLNFLPEQEHSEVYKILSSHMLVTDSPSPEFLKSDNDLEFYCHLLRGSLNPKEFPTYEYIKFVGNFRSYNNVPSPSCNGFDNTLSRPCRVPLGKEVCFIATVRLATPQFLKEMCVADEPLEEFTSRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYDYYHIDDLELLARCHQHLMQFGKGKSCCYRFLTKGQQWIWLQTHYYITYHQWNSKPEFIVCTHSVVSYADVRVERRQELALEDPPTEAMHPSALKEKDSSLEPQPHFNALDMGASGLTSSPSPSASSRSSHKSSHTAMSEPTSTPTKLMAENSTTALPRSATLPQELPVQGLSQAATMPAPLLSSSSCDLAKQLLPQSLPQTVLQSPPAPVTQFSAQFSMFQTIKDQLEQRTRILQANIRWQQEELHKIQEQLCLVQDSNVQMFLQQPAVSLSFSGAQRPAAQQPLQQRPSAPSQPPLVVNTPLPGQITSTQVTNQHLLRESNVMSAQGPKPIRSSQLLPASSRSLSSLPSQFSSTASVLPPGLSLTTVAPTPQDTSQCQPSPDFGHDRQLRLLLSQPIQPMMPGSCDARQPSEVSRTGRQVKYAQSQVTFPSPDSHPTSSSAPTPVLLMGQAVLHPGFPASQPSPLQPTQVQQQPPPYLQAPTSLHSEQPDSLLLSTFSQQPAPLGYAATQPTQPQPPRPSRRVSRLSES

Target ORF information:

RefSeq Version	XM_008767033.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus neuronal PAS domain protein 2 (Npas2), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008767033.2

ORF Insert Sequence:

ATGGACGAAG ATGAGAAGGA TAGAGCAAAG AGAGCCTCTC GAAACAAGTC TGAGAAGAAG 
CGTCGGGACC AGTTCAATGT TCTCATCAAA GAGCTCAGCT CCATGCTCCC AGGCAACACT 
CGGAAACTGG ACAAAACAAC TGTGCTGGAG AAGGTCATCG GATTTCTGCA GAAACACAAT 
GAAGTCTCAG CACAAACAGA AATCTGTGAC ATCCAGCAGG ACTGGAAGCC TTCATTCCTC 
AGTAACGAAG AATTCACCCA GCTGATGTTG GAGGCGTTAG ATGGCTTCGT CATTGTTGTG 
ACAACGGACG GCAGCATCAT CTATGTGTCC GACAGCATCA CGCCTCTCCT CGGACATTTA 
CCGTCGGATG TCATGGATCA GAACTTGTTA AATTTCCTTC CAGAACAAGA ACATTCCGAA 
GTTTATAAAA TCCTTTCCTC CCATATGCTT GTGACGGATT CCCCCTCCCC AGAATTCCTA 
AAATCTGACA ACGATTTAGA GTTTTATTGT CATCTTCTGA GAGGCAGCTT GAACCCAAAG 
GAATTTCCAA CTTACGAATA CATAAAATTT GTAGGAAATT TTCGCTCTTA CAACAATGTG 
CCTAGCCCCT CCTGTAATGG CTTTGACAAC ACCCTTTCAA GACCCTGCCG CGTGCCCCTG 
GGGAAGGAGG TCTGCTTCAT CGCCACGGTG CGCCTGGCAA CACCACAGTT CTTAAAGGAA 
ATGTGTGTAG CTGACGAACC TTTAGAGGAA TTCACTTCGA GGCATAGCTT GGAATGGAAA 
TTTTTATTTC TGGATCACAG AGCCCCTCCA ATCATAGGAT ACCTGCCCTT TGAAGTACTT 
GGCACGTCAG GCTATGACTA CTACCACATT GATGACCTGG AGCTCCTGGC CAGGTGCCAC 
CAGCACTTGA TGCAGTTTGG CAAAGGGAAG TCGTGTTGTT ACCGGTTTCT AACCAAAGGA 
CAGCAGTGGA TTTGGTTGCA AACCCACTAC TACATCACCT ACCACCAGTG GAACTCCAAG 
CCCGAGTTCA TCGTGTGCAC ACACTCGGTG GTCAGTTACG CAGATGTCCG AGTGGAAAGG 
AGACAGGAGC TGGCTCTGGA AGATCCACCC ACAGAAGCCA TGCACCCCTC TGCACTGAAG 
GAAAAGGACT CAAGCCTAGA GCCTCAGCCG CACTTTAATG CACTTGACAT GGGTGCCTCA 
GGTCTTACCA GCAGTCCTTC GCCATCAGCA TCCTCGAGGA GTTCCCACAA GTCCTCACAC 
ACAGCCATGT CAGAACCCAC CTCCACTCCA ACCAAGCTGA TGGCTGAGAA CAGCACCACA 
GCTTTGCCAA GATCAGCCAC CCTACCCCAG GAGTTACCAG TGCAGGGGCT CAGCCAGGCA 
GCCACAATGC CAGCTCCTCT GCTTTCCTCA TCATCCTGTG ACCTTGCCAA GCAGCTCCTG 
CCTCAGTCCC TGCCTCAGAC GGTCCTGCAG AGTCCACCTG CTCCAGTGAC ACAGTTTTCA 
GCACAATTTA GCATGTTCCA GACCATAAAA GACCAGTTGG AGCAGAGGAC ACGGATCCTG 
CAGGCCAACA TTCGGTGGCA GCAGGAAGAG CTTCACAAGA TCCAGGAACA ACTCTGCCTG 
GTCCAGGACT CCAACGTCCA GATGTTTCTA CAGCAGCCAG CGGTGTCTCT GAGCTTCAGC 
GGTGCCCAGA GACCGGCAGC TCAGCAGCCA CTGCAACAAA GGCCATCTGC ACCGTCTCAG 
CCCCCGCTTG TGGTCAACAC TCCACTGCCG GGGCAGATCA CATCCACCCA AGTCACAAAC 
CAGCACCTGC TCAGAGAATC GAATGTGATG TCCGCCCAGG GTCCAAAACC AATAAGAAGC 
TCCCAGTTGC TGCCTGCCAG CAGCCGTTCA CTGAGCAGCC TGCCGTCCCA GTTCAGCAGC 
ACAGCGTCCG TGCTCCCACC AGGCCTGAGC CTCACCACTG TCGCTCCCAC CCCTCAGGAC 
ACCAGCCAGT GCCAGCCCAG CCCTGACTTC GGCCATGATC GGCAGCTCAG GCTGTTGCTG 
AGCCAACCCA TCCAGCCTAT GATGCCTGGG TCTTGTGATG CCAGGCAGCC CTCAGAAGTC 
AGCAGGACTG GACGGCAAGT CAAATATGCA CAGAGCCAAG TGACGTTTCC AAGTCCTGAC 
TCCCACCCCA CCAGCAGCAG CGCCCCCACC CCGGTCCTGT TGATGGGGCA GGCCGTGCTC 
CATCCCGGCT TCCCCGCATC CCAGCCATCA CCCCTGCAAC CAACACAGGT ACAACAGCAG 
CCACCACCCT ATCTACAGGC ACCAACATCT CTGCACAGTG AACAGCCGGA CTCGCTCCTT 
CTCTCCACCT TCTCCCAGCA GCCAGCACCT CTGGGCTATG CAGCCACACA GCCTACACAG 
CCGCAACCCC CACGCCCTTC CCGCAGGGTC AGCCGGCTGT CAGAGTCCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Npas2 ( XM_008767031.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008765253.1 Rattus norvegicus neuronal PAS domain protein 2 (Npas2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa12717
Clone ID Related Accession (Same CDS sequence)	XM_008767033.2 , NM_001108214.2 , XM_008767031.2 , XM_008767032.2
Accession Version	XM_008767031.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2451bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	neuronal PAS domain-containing protein 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005108.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008767031.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACGAAG ATGAGAAGGA TAGAGCAAAG AGAGCCTCTC GAAACAAGTC TGAGAAGAAG 
CGTCGGGACC AGTTCAATGT TCTCATCAAA GAGCTCAGCT CCATGCTCCC AGGCAACACT 
CGGAAACTGG ACAAAACAAC TGTGCTGGAG AAGGTCATCG GATTTCTGCA GAAACACAAT 
GAAGTCTCAG CACAAACAGA AATCTGTGAC ATCCAGCAGG ACTGGAAGCC TTCATTCCTC 
AGTAACGAAG AATTCACCCA GCTGATGTTG GAGGCGTTAG ATGGCTTCGT CATTGTTGTG 
ACAACGGACG GCAGCATCAT CTATGTGTCC GACAGCATCA CGCCTCTCCT CGGACATTTA 
CCGTCGGATG TCATGGATCA GAACTTGTTA AATTTCCTTC CAGAACAAGA ACATTCCGAA 
GTTTATAAAA TCCTTTCCTC CCATATGCTT GTGACGGATT CCCCCTCCCC AGAATTCCTA 
AAATCTGACA ACGATTTAGA GTTTTATTGT CATCTTCTGA GAGGCAGCTT GAACCCAAAG 
GAATTTCCAA CTTACGAATA CATAAAATTT GTAGGAAATT TTCGCTCTTA CAACAATGTG 
CCTAGCCCCT CCTGTAATGG CTTTGACAAC ACCCTTTCAA GACCCTGCCG CGTGCCCCTG 
GGGAAGGAGG TCTGCTTCAT CGCCACGGTG CGCCTGGCAA CACCACAGTT CTTAAAGGAA 
ATGTGTGTAG CTGACGAACC TTTAGAGGAA TTCACTTCGA GGCATAGCTT GGAATGGAAA 
TTTTTATTTC TGGATCACAG AGCCCCTCCA ATCATAGGAT ACCTGCCCTT TGAAGTACTT 
GGCACGTCAG GCTATGACTA CTACCACATT GATGACCTGG AGCTCCTGGC CAGGTGCCAC 
CAGCACTTGA TGCAGTTTGG CAAAGGGAAG TCGTGTTGTT ACCGGTTTCT AACCAAAGGA 
CAGCAGTGGA TTTGGTTGCA AACCCACTAC TACATCACCT ACCACCAGTG GAACTCCAAG 
CCCGAGTTCA TCGTGTGCAC ACACTCGGTG GTCAGTTACG CAGATGTCCG AGTGGAAAGG 
AGACAGGAGC TGGCTCTGGA AGATCCACCC ACAGAAGCCA TGCACCCCTC TGCACTGAAG 
GAAAAGGACT CAAGCCTAGA GCCTCAGCCG CACTTTAATG CACTTGACAT GGGTGCCTCA 
GGTCTTACCA GCAGTCCTTC GCCATCAGCA TCCTCGAGGA GTTCCCACAA GTCCTCACAC 
ACAGCCATGT CAGAACCCAC CTCCACTCCA ACCAAGCTGA TGGCTGAGAA CAGCACCACA 
GCTTTGCCAA GATCAGCCAC CCTACCCCAG GAGTTACCAG TGCAGGGGCT CAGCCAGGCA 
GCCACAATGC CAGCTCCTCT GCTTTCCTCA TCATCCTGTG ACCTTGCCAA GCAGCTCCTG 
CCTCAGTCCC TGCCTCAGAC GGTCCTGCAG AGTCCACCTG CTCCAGTGAC ACAGTTTTCA 
GCACAATTTA GCATGTTCCA GACCATAAAA GACCAGTTGG AGCAGAGGAC ACGGATCCTG 
CAGGCCAACA TTCGGTGGCA GCAGGAAGAG CTTCACAAGA TCCAGGAACA ACTCTGCCTG 
GTCCAGGACT CCAACGTCCA GATGTTTCTA CAGCAGCCAG CGGTGTCTCT GAGCTTCAGC 
GGTGCCCAGA GACCGGCAGC TCAGCAGCCA CTGCAACAAA GGCCATCTGC ACCGTCTCAG 
CCCCCGCTTG TGGTCAACAC TCCACTGCCG GGGCAGATCA CATCCACCCA AGTCACAAAC 
CAGCACCTGC TCAGAGAATC GAATGTGATG TCCGCCCAGG GTCCAAAACC AATAAGAAGC 
TCCCAGTTGC TGCCTGCCAG CAGCCGTTCA CTGAGCAGCC TGCCGTCCCA GTTCAGCAGC 
ACAGCGTCCG TGCTCCCACC AGGCCTGAGC CTCACCACTG TCGCTCCCAC CCCTCAGGAC 
ACCAGCCAGT GCCAGCCCAG CCCTGACTTC GGCCATGATC GGCAGCTCAG GCTGTTGCTG 
AGCCAACCCA TCCAGCCTAT GATGCCTGGG TCTTGTGATG CCAGGCAGCC CTCAGAAGTC 
AGCAGGACTG GACGGCAAGT CAAATATGCA CAGAGCCAAG TGACGTTTCC AAGTCCTGAC 
TCCCACCCCA CCAGCAGCAG CGCCCCCACC CCGGTCCTGT TGATGGGGCA GGCCGTGCTC 
CATCCCGGCT TCCCCGCATC CCAGCCATCA CCCCTGCAAC CAACACAGGT ACAACAGCAG 
CCACCACCCT ATCTACAGGC ACCAACATCT CTGCACAGTG AACAGCCGGA CTCGCTCCTT 
CTCTCCACCT TCTCCCAGCA GCCAGCACCT CTGGGCTATG CAGCCACACA GCCTACACAG 
CCGCAACCCC CACGCCCTTC CCGCAGGGTC AGCCGGCTGT CAGAGTCCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008765253.1
CDS	300..2750
Translation	MDEDEKDRAKRASRNKSEKKRRDQFNVLIKELSSMLPGNTRKLDKTTVLEKVIGFLQKHNEVSAQTEICDIQQDWKPSFLSNEEFTQLMLEALDGFVIVVTTDGSIIYVSDSITPLLGHLPSDVMDQNLLNFLPEQEHSEVYKILSSHMLVTDSPSPEFLKSDNDLEFYCHLLRGSLNPKEFPTYEYIKFVGNFRSYNNVPSPSCNGFDNTLSRPCRVPLGKEVCFIATVRLATPQFLKEMCVADEPLEEFTSRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYDYYHIDDLELLARCHQHLMQFGKGKSCCYRFLTKGQQWIWLQTHYYITYHQWNSKPEFIVCTHSVVSYADVRVERRQELALEDPPTEAMHPSALKEKDSSLEPQPHFNALDMGASGLTSSPSPSASSRSSHKSSHTAMSEPTSTPTKLMAENSTTALPRSATLPQELPVQGLSQAATMPAPLLSSSSCDLAKQLLPQSLPQTVLQSPPAPVTQFSAQFSMFQTIKDQLEQRTRILQANIRWQQEELHKIQEQLCLVQDSNVQMFLQQPAVSLSFSGAQRPAAQQPLQQRPSAPSQPPLVVNTPLPGQITSTQVTNQHLLRESNVMSAQGPKPIRSSQLLPASSRSLSSLPSQFSSTASVLPPGLSLTTVAPTPQDTSQCQPSPDFGHDRQLRLLLSQPIQPMMPGSCDARQPSEVSRTGRQVKYAQSQVTFPSPDSHPTSSSAPTPVLLMGQAVLHPGFPASQPSPLQPTQVQQQPPPYLQAPTSLHSEQPDSLLLSTFSQQPAPLGYAATQPTQPQPPRPSRRVSRLSES

Target ORF information:

RefSeq Version	XM_008767031.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus neuronal PAS domain protein 2 (Npas2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008767031.2

ORF Insert Sequence:

ATGGACGAAG ATGAGAAGGA TAGAGCAAAG AGAGCCTCTC GAAACAAGTC TGAGAAGAAG 
CGTCGGGACC AGTTCAATGT TCTCATCAAA GAGCTCAGCT CCATGCTCCC AGGCAACACT 
CGGAAACTGG ACAAAACAAC TGTGCTGGAG AAGGTCATCG GATTTCTGCA GAAACACAAT 
GAAGTCTCAG CACAAACAGA AATCTGTGAC ATCCAGCAGG ACTGGAAGCC TTCATTCCTC 
AGTAACGAAG AATTCACCCA GCTGATGTTG GAGGCGTTAG ATGGCTTCGT CATTGTTGTG 
ACAACGGACG GCAGCATCAT CTATGTGTCC GACAGCATCA CGCCTCTCCT CGGACATTTA 
CCGTCGGATG TCATGGATCA GAACTTGTTA AATTTCCTTC CAGAACAAGA ACATTCCGAA 
GTTTATAAAA TCCTTTCCTC CCATATGCTT GTGACGGATT CCCCCTCCCC AGAATTCCTA 
AAATCTGACA ACGATTTAGA GTTTTATTGT CATCTTCTGA GAGGCAGCTT GAACCCAAAG 
GAATTTCCAA CTTACGAATA CATAAAATTT GTAGGAAATT TTCGCTCTTA CAACAATGTG 
CCTAGCCCCT CCTGTAATGG CTTTGACAAC ACCCTTTCAA GACCCTGCCG CGTGCCCCTG 
GGGAAGGAGG TCTGCTTCAT CGCCACGGTG CGCCTGGCAA CACCACAGTT CTTAAAGGAA 
ATGTGTGTAG CTGACGAACC TTTAGAGGAA TTCACTTCGA GGCATAGCTT GGAATGGAAA 
TTTTTATTTC TGGATCACAG AGCCCCTCCA ATCATAGGAT ACCTGCCCTT TGAAGTACTT 
GGCACGTCAG GCTATGACTA CTACCACATT GATGACCTGG AGCTCCTGGC CAGGTGCCAC 
CAGCACTTGA TGCAGTTTGG CAAAGGGAAG TCGTGTTGTT ACCGGTTTCT AACCAAAGGA 
CAGCAGTGGA TTTGGTTGCA AACCCACTAC TACATCACCT ACCACCAGTG GAACTCCAAG 
CCCGAGTTCA TCGTGTGCAC ACACTCGGTG GTCAGTTACG CAGATGTCCG AGTGGAAAGG 
AGACAGGAGC TGGCTCTGGA AGATCCACCC ACAGAAGCCA TGCACCCCTC TGCACTGAAG 
GAAAAGGACT CAAGCCTAGA GCCTCAGCCG CACTTTAATG CACTTGACAT GGGTGCCTCA 
GGTCTTACCA GCAGTCCTTC GCCATCAGCA TCCTCGAGGA GTTCCCACAA GTCCTCACAC 
ACAGCCATGT CAGAACCCAC CTCCACTCCA ACCAAGCTGA TGGCTGAGAA CAGCACCACA 
GCTTTGCCAA GATCAGCCAC CCTACCCCAG GAGTTACCAG TGCAGGGGCT CAGCCAGGCA 
GCCACAATGC CAGCTCCTCT GCTTTCCTCA TCATCCTGTG ACCTTGCCAA GCAGCTCCTG 
CCTCAGTCCC TGCCTCAGAC GGTCCTGCAG AGTCCACCTG CTCCAGTGAC ACAGTTTTCA 
GCACAATTTA GCATGTTCCA GACCATAAAA GACCAGTTGG AGCAGAGGAC ACGGATCCTG 
CAGGCCAACA TTCGGTGGCA GCAGGAAGAG CTTCACAAGA TCCAGGAACA ACTCTGCCTG 
GTCCAGGACT CCAACGTCCA GATGTTTCTA CAGCAGCCAG CGGTGTCTCT GAGCTTCAGC 
GGTGCCCAGA GACCGGCAGC TCAGCAGCCA CTGCAACAAA GGCCATCTGC ACCGTCTCAG 
CCCCCGCTTG TGGTCAACAC TCCACTGCCG GGGCAGATCA CATCCACCCA AGTCACAAAC 
CAGCACCTGC TCAGAGAATC GAATGTGATG TCCGCCCAGG GTCCAAAACC AATAAGAAGC 
TCCCAGTTGC TGCCTGCCAG CAGCCGTTCA CTGAGCAGCC TGCCGTCCCA GTTCAGCAGC 
ACAGCGTCCG TGCTCCCACC AGGCCTGAGC CTCACCACTG TCGCTCCCAC CCCTCAGGAC 
ACCAGCCAGT GCCAGCCCAG CCCTGACTTC GGCCATGATC GGCAGCTCAG GCTGTTGCTG 
AGCCAACCCA TCCAGCCTAT GATGCCTGGG TCTTGTGATG CCAGGCAGCC CTCAGAAGTC 
AGCAGGACTG GACGGCAAGT CAAATATGCA CAGAGCCAAG TGACGTTTCC AAGTCCTGAC 
TCCCACCCCA CCAGCAGCAG CGCCCCCACC CCGGTCCTGT TGATGGGGCA GGCCGTGCTC 
CATCCCGGCT TCCCCGCATC CCAGCCATCA CCCCTGCAAC CAACACAGGT ACAACAGCAG 
CCACCACCCT ATCTACAGGC ACCAACATCT CTGCACAGTG AACAGCCGGA CTCGCTCCTT 
CTCTCCACCT TCTCCCAGCA GCCAGCACCT CTGGGCTATG CAGCCACACA GCCTACACAG 
CCGCAACCCC CACGCCCTTC CCGCAGGGTC AGCCGGCTGT CAGAGTCCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Npas2 ( XM_008767032.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008765254.1 Rattus norvegicus neuronal PAS domain protein 2 (Npas2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa12717
Clone ID Related Accession (Same CDS sequence)	XM_008767033.2 , NM_001108214.2 , XM_008767031.2 , XM_008767032.2
Accession Version	XM_008767032.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2451bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	neuronal PAS domain-containing protein 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005108.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008767032.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACGAAG ATGAGAAGGA TAGAGCAAAG AGAGCCTCTC GAAACAAGTC TGAGAAGAAG 
CGTCGGGACC AGTTCAATGT TCTCATCAAA GAGCTCAGCT CCATGCTCCC AGGCAACACT 
CGGAAACTGG ACAAAACAAC TGTGCTGGAG AAGGTCATCG GATTTCTGCA GAAACACAAT 
GAAGTCTCAG CACAAACAGA AATCTGTGAC ATCCAGCAGG ACTGGAAGCC TTCATTCCTC 
AGTAACGAAG AATTCACCCA GCTGATGTTG GAGGCGTTAG ATGGCTTCGT CATTGTTGTG 
ACAACGGACG GCAGCATCAT CTATGTGTCC GACAGCATCA CGCCTCTCCT CGGACATTTA 
CCGTCGGATG TCATGGATCA GAACTTGTTA AATTTCCTTC CAGAACAAGA ACATTCCGAA 
GTTTATAAAA TCCTTTCCTC CCATATGCTT GTGACGGATT CCCCCTCCCC AGAATTCCTA 
AAATCTGACA ACGATTTAGA GTTTTATTGT CATCTTCTGA GAGGCAGCTT GAACCCAAAG 
GAATTTCCAA CTTACGAATA CATAAAATTT GTAGGAAATT TTCGCTCTTA CAACAATGTG 
CCTAGCCCCT CCTGTAATGG CTTTGACAAC ACCCTTTCAA GACCCTGCCG CGTGCCCCTG 
GGGAAGGAGG TCTGCTTCAT CGCCACGGTG CGCCTGGCAA CACCACAGTT CTTAAAGGAA 
ATGTGTGTAG CTGACGAACC TTTAGAGGAA TTCACTTCGA GGCATAGCTT GGAATGGAAA 
TTTTTATTTC TGGATCACAG AGCCCCTCCA ATCATAGGAT ACCTGCCCTT TGAAGTACTT 
GGCACGTCAG GCTATGACTA CTACCACATT GATGACCTGG AGCTCCTGGC CAGGTGCCAC 
CAGCACTTGA TGCAGTTTGG CAAAGGGAAG TCGTGTTGTT ACCGGTTTCT AACCAAAGGA 
CAGCAGTGGA TTTGGTTGCA AACCCACTAC TACATCACCT ACCACCAGTG GAACTCCAAG 
CCCGAGTTCA TCGTGTGCAC ACACTCGGTG GTCAGTTACG CAGATGTCCG AGTGGAAAGG 
AGACAGGAGC TGGCTCTGGA AGATCCACCC ACAGAAGCCA TGCACCCCTC TGCACTGAAG 
GAAAAGGACT CAAGCCTAGA GCCTCAGCCG CACTTTAATG CACTTGACAT GGGTGCCTCA 
GGTCTTACCA GCAGTCCTTC GCCATCAGCA TCCTCGAGGA GTTCCCACAA GTCCTCACAC 
ACAGCCATGT CAGAACCCAC CTCCACTCCA ACCAAGCTGA TGGCTGAGAA CAGCACCACA 
GCTTTGCCAA GATCAGCCAC CCTACCCCAG GAGTTACCAG TGCAGGGGCT CAGCCAGGCA 
GCCACAATGC CAGCTCCTCT GCTTTCCTCA TCATCCTGTG ACCTTGCCAA GCAGCTCCTG 
CCTCAGTCCC TGCCTCAGAC GGTCCTGCAG AGTCCACCTG CTCCAGTGAC ACAGTTTTCA 
GCACAATTTA GCATGTTCCA GACCATAAAA GACCAGTTGG AGCAGAGGAC ACGGATCCTG 
CAGGCCAACA TTCGGTGGCA GCAGGAAGAG CTTCACAAGA TCCAGGAACA ACTCTGCCTG 
GTCCAGGACT CCAACGTCCA GATGTTTCTA CAGCAGCCAG CGGTGTCTCT GAGCTTCAGC 
GGTGCCCAGA GACCGGCAGC TCAGCAGCCA CTGCAACAAA GGCCATCTGC ACCGTCTCAG 
CCCCCGCTTG TGGTCAACAC TCCACTGCCG GGGCAGATCA CATCCACCCA AGTCACAAAC 
CAGCACCTGC TCAGAGAATC GAATGTGATG TCCGCCCAGG GTCCAAAACC AATAAGAAGC 
TCCCAGTTGC TGCCTGCCAG CAGCCGTTCA CTGAGCAGCC TGCCGTCCCA GTTCAGCAGC 
ACAGCGTCCG TGCTCCCACC AGGCCTGAGC CTCACCACTG TCGCTCCCAC CCCTCAGGAC 
ACCAGCCAGT GCCAGCCCAG CCCTGACTTC GGCCATGATC GGCAGCTCAG GCTGTTGCTG 
AGCCAACCCA TCCAGCCTAT GATGCCTGGG TCTTGTGATG CCAGGCAGCC CTCAGAAGTC 
AGCAGGACTG GACGGCAAGT CAAATATGCA CAGAGCCAAG TGACGTTTCC AAGTCCTGAC 
TCCCACCCCA CCAGCAGCAG CGCCCCCACC CCGGTCCTGT TGATGGGGCA GGCCGTGCTC 
CATCCCGGCT TCCCCGCATC CCAGCCATCA CCCCTGCAAC CAACACAGGT ACAACAGCAG 
CCACCACCCT ATCTACAGGC ACCAACATCT CTGCACAGTG AACAGCCGGA CTCGCTCCTT 
CTCTCCACCT TCTCCCAGCA GCCAGCACCT CTGGGCTATG CAGCCACACA GCCTACACAG 
CCGCAACCCC CACGCCCTTC CCGCAGGGTC AGCCGGCTGT CAGAGTCCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008765254.1
CDS	1273..3723
Translation	MDEDEKDRAKRASRNKSEKKRRDQFNVLIKELSSMLPGNTRKLDKTTVLEKVIGFLQKHNEVSAQTEICDIQQDWKPSFLSNEEFTQLMLEALDGFVIVVTTDGSIIYVSDSITPLLGHLPSDVMDQNLLNFLPEQEHSEVYKILSSHMLVTDSPSPEFLKSDNDLEFYCHLLRGSLNPKEFPTYEYIKFVGNFRSYNNVPSPSCNGFDNTLSRPCRVPLGKEVCFIATVRLATPQFLKEMCVADEPLEEFTSRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYDYYHIDDLELLARCHQHLMQFGKGKSCCYRFLTKGQQWIWLQTHYYITYHQWNSKPEFIVCTHSVVSYADVRVERRQELALEDPPTEAMHPSALKEKDSSLEPQPHFNALDMGASGLTSSPSPSASSRSSHKSSHTAMSEPTSTPTKLMAENSTTALPRSATLPQELPVQGLSQAATMPAPLLSSSSCDLAKQLLPQSLPQTVLQSPPAPVTQFSAQFSMFQTIKDQLEQRTRILQANIRWQQEELHKIQEQLCLVQDSNVQMFLQQPAVSLSFSGAQRPAAQQPLQQRPSAPSQPPLVVNTPLPGQITSTQVTNQHLLRESNVMSAQGPKPIRSSQLLPASSRSLSSLPSQFSSTASVLPPGLSLTTVAPTPQDTSQCQPSPDFGHDRQLRLLLSQPIQPMMPGSCDARQPSEVSRTGRQVKYAQSQVTFPSPDSHPTSSSAPTPVLLMGQAVLHPGFPASQPSPLQPTQVQQQPPPYLQAPTSLHSEQPDSLLLSTFSQQPAPLGYAATQPTQPQPPRPSRRVSRLSES

Target ORF information:

RefSeq Version	XM_008767032.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus neuronal PAS domain protein 2 (Npas2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008767032.2

ORF Insert Sequence:

ATGGACGAAG ATGAGAAGGA TAGAGCAAAG AGAGCCTCTC GAAACAAGTC TGAGAAGAAG 
CGTCGGGACC AGTTCAATGT TCTCATCAAA GAGCTCAGCT CCATGCTCCC AGGCAACACT 
CGGAAACTGG ACAAAACAAC TGTGCTGGAG AAGGTCATCG GATTTCTGCA GAAACACAAT 
GAAGTCTCAG CACAAACAGA AATCTGTGAC ATCCAGCAGG ACTGGAAGCC TTCATTCCTC 
AGTAACGAAG AATTCACCCA GCTGATGTTG GAGGCGTTAG ATGGCTTCGT CATTGTTGTG 
ACAACGGACG GCAGCATCAT CTATGTGTCC GACAGCATCA CGCCTCTCCT CGGACATTTA 
CCGTCGGATG TCATGGATCA GAACTTGTTA AATTTCCTTC CAGAACAAGA ACATTCCGAA 
GTTTATAAAA TCCTTTCCTC CCATATGCTT GTGACGGATT CCCCCTCCCC AGAATTCCTA 
AAATCTGACA ACGATTTAGA GTTTTATTGT CATCTTCTGA GAGGCAGCTT GAACCCAAAG 
GAATTTCCAA CTTACGAATA CATAAAATTT GTAGGAAATT TTCGCTCTTA CAACAATGTG 
CCTAGCCCCT CCTGTAATGG CTTTGACAAC ACCCTTTCAA GACCCTGCCG CGTGCCCCTG 
GGGAAGGAGG TCTGCTTCAT CGCCACGGTG CGCCTGGCAA CACCACAGTT CTTAAAGGAA 
ATGTGTGTAG CTGACGAACC TTTAGAGGAA TTCACTTCGA GGCATAGCTT GGAATGGAAA 
TTTTTATTTC TGGATCACAG AGCCCCTCCA ATCATAGGAT ACCTGCCCTT TGAAGTACTT 
GGCACGTCAG GCTATGACTA CTACCACATT GATGACCTGG AGCTCCTGGC CAGGTGCCAC 
CAGCACTTGA TGCAGTTTGG CAAAGGGAAG TCGTGTTGTT ACCGGTTTCT AACCAAAGGA 
CAGCAGTGGA TTTGGTTGCA AACCCACTAC TACATCACCT ACCACCAGTG GAACTCCAAG 
CCCGAGTTCA TCGTGTGCAC ACACTCGGTG GTCAGTTACG CAGATGTCCG AGTGGAAAGG 
AGACAGGAGC TGGCTCTGGA AGATCCACCC ACAGAAGCCA TGCACCCCTC TGCACTGAAG 
GAAAAGGACT CAAGCCTAGA GCCTCAGCCG CACTTTAATG CACTTGACAT GGGTGCCTCA 
GGTCTTACCA GCAGTCCTTC GCCATCAGCA TCCTCGAGGA GTTCCCACAA GTCCTCACAC 
ACAGCCATGT CAGAACCCAC CTCCACTCCA ACCAAGCTGA TGGCTGAGAA CAGCACCACA 
GCTTTGCCAA GATCAGCCAC CCTACCCCAG GAGTTACCAG TGCAGGGGCT CAGCCAGGCA 
GCCACAATGC CAGCTCCTCT GCTTTCCTCA TCATCCTGTG ACCTTGCCAA GCAGCTCCTG 
CCTCAGTCCC TGCCTCAGAC GGTCCTGCAG AGTCCACCTG CTCCAGTGAC ACAGTTTTCA 
GCACAATTTA GCATGTTCCA GACCATAAAA GACCAGTTGG AGCAGAGGAC ACGGATCCTG 
CAGGCCAACA TTCGGTGGCA GCAGGAAGAG CTTCACAAGA TCCAGGAACA ACTCTGCCTG 
GTCCAGGACT CCAACGTCCA GATGTTTCTA CAGCAGCCAG CGGTGTCTCT GAGCTTCAGC 
GGTGCCCAGA GACCGGCAGC TCAGCAGCCA CTGCAACAAA GGCCATCTGC ACCGTCTCAG 
CCCCCGCTTG TGGTCAACAC TCCACTGCCG GGGCAGATCA CATCCACCCA AGTCACAAAC 
CAGCACCTGC TCAGAGAATC GAATGTGATG TCCGCCCAGG GTCCAAAACC AATAAGAAGC 
TCCCAGTTGC TGCCTGCCAG CAGCCGTTCA CTGAGCAGCC TGCCGTCCCA GTTCAGCAGC 
ACAGCGTCCG TGCTCCCACC AGGCCTGAGC CTCACCACTG TCGCTCCCAC CCCTCAGGAC 
ACCAGCCAGT GCCAGCCCAG CCCTGACTTC GGCCATGATC GGCAGCTCAG GCTGTTGCTG 
AGCCAACCCA TCCAGCCTAT GATGCCTGGG TCTTGTGATG CCAGGCAGCC CTCAGAAGTC 
AGCAGGACTG GACGGCAAGT CAAATATGCA CAGAGCCAAG TGACGTTTCC AAGTCCTGAC 
TCCCACCCCA CCAGCAGCAG CGCCCCCACC CCGGTCCTGT TGATGGGGCA GGCCGTGCTC 
CATCCCGGCT TCCCCGCATC CCAGCCATCA CCCCTGCAAC CAACACAGGT ACAACAGCAG 
CCACCACCCT ATCTACAGGC ACCAACATCT CTGCACAGTG AACAGCCGGA CTCGCTCCTT 
CTCTCCACCT TCTCCCAGCA GCCAGCACCT CTGGGCTATG CAGCCACACA GCCTACACAG 
CCGCAACCCC CACGCCCTTC CCGCAGGGTC AGCCGGCTGT CAGAGTCCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Prefrontal cortex and dorsomedial hypothalamus mediate food reward-induced effects via npas2 and egr1 expression in rat.
Physiological research66(Supplementum 4)S501-S510(2017 Dec)
Herichov? I,Has?kov? K,Luk??ov? D,Mravec B,Horv?thov? ?,Kavick? D

NPAS2 Regulation of Anxiety-Like Behavior and GABAA Receptors.
Frontiers in molecular neuroscience10360(2017)
Ozburn AR,Kern J,Parekh PK,Logan RW,Liu Z,Falcon E,Becker-Krail D,Purohit K,Edgar NM,Huang Y,McClung CA

Small heterodimer partner/neuronal PAS domain protein 2 axis regulates the oscillation of liver lipid metabolism.
Hepatology (Baltimore, Md.)61(2)497-505(2015 Feb)
Lee SM,Zhang Y,Tsuchiya H,Smalling R,Jetten AM,Wang L

Circadian rhythm of contrast sensitivity is regulated by a dopamine-neuronal PAS-domain protein 2-adenylyl cyclase 1 signaling pathway in retinal ganglion cells.
The Journal of neuroscience : the official journal of the Society for Neuroscience33(38)14989-97(2013 Sep)
Hwang CK,Chaurasia SS,Jackson CR,Chan GC,Storm DR,Iuvone PM

Effect of streptozotocin-induced diabetes on clock gene expression in tissues inside and outside the blood-brain barrier in rat.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association121(8)466-74(2013 Aug)
?olt?sov? D,Mono??kov? J,Koy?ov? L,Vesel? A,Mravec B,Herichov? I

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Npas2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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