Ttbk1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ttbk1
Entrez Gene ID	316229
Full Name	tau tubulin kinase 1
Synonyms	RGD1559518
General protein information	Preferred Names tau tubulin kinase 1 Names tau-tubulin kinase 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 9 Map Location: 9q12

mRNA and Protein(s)

mRNA	Protein	Name
NM_001271230.1	NP_001258159.1	tau-tubulin kinase 1

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Ttbk1	NP_001156336.1
Pan troglodytes (chimpanzee)	TTBK1	XP_003311367.1
Gallus gallus (chicken)	TTBK1	NP_001186368.1
Homo sapiens (human)	TTBK1	NP_115927.1
	TTBK1	XP_001088342.2
Rattus norvegicus (Norway rat)	Ttbk1	NP_001258159.1
Canis lupus familiaris (dog)	TTBK1	XP_005627821.1
Danio rerio (zebrafish)	LOC100332125	XP_002663847.3

Gene Ontology
Bibliography

Related articles in PubMed

TTBK2 with EB1/3 regulates microtubule dynamics in migrating cells through KIF2A phosphorylation.
Watanabe T, Kakeno M, Matsui T, Sugiyama I, Arimura N, Matsuzawa K, Shirahige A, Ishidate F, Nishioka T, Taya S, Hoshino M, Kaibuchi K
The Journal of cell biology210(5)737-51(2015 Aug)

Quantitative proteomic analysis of human substantia nigra in Alzheimer's disease, Huntington's disease and Multiple sclerosis.
Chen S, Lu FF, Seeman P, Liu F
Neurochemical research37(12)2805-13(2012 Dec)

Spatial learning impairment, enhanced CDK5/p35 activity, and downregulation of NMDA receptor expression in transgenic mice expressing tau-tubulin kinase 1.
Sato S, Xu J, Okuyama S, Martinez LB, Walsh SM, Jacobsen MT, Swan RJ, Schlautman JD, Ciborowski P, Ikezu T
The Journal of neuroscience : the official journal of the Society for Neuroscience28(53)14511-21(2008 Dec)

Tau-tubulin kinase 1 (TTBK1), a neuron-specific tau kinase candidate, is involved in tau phosphorylation and aggregation.
Sato S, Cerny RL, Buescher JL, Ikezu T
Journal of neurochemistry98(5)1573-84(2006 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Ttbk1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ttbk1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa10668	NM_001271230.1 Latest version!	Rattus norvegicus tau tubulin kinase 1 (Ttbk1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$643.30 $919.00

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ttbk1 ( NM_001271230.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001258159.1 Rattus norvegicus tau tubulin kinase 1 (Ttbk1), mRNA.

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CloneID	ORa10668
Clone ID Related Accession (Same CDS sequence)	NM_001271230.1
Accession Version	NM_001271230.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3924bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-28
Organism	Rattus norvegicus(Norway rat)
Product	tau-tubulin kinase 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AAHX01058291.1 and AAHX01058292.1. On or before Sep 9, 2012 this sequence version replaced XM_244043.5, XM_001066190.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGCAGTGCC TAGCGGCTGC TCTTAAAGAC GAAACCAACA TGAGTGGGGG AGGGGAGCAG 
GCCGACATCC TGCCGGCCAA CTACGTGGTC AAAGATCGCT GGAAGGTGCT GAAAAAGATC 
GGGGGCGGGG GCTTCGGTGA GATCTATGAG GCCATGGACC TGCTGACCAG GGAGAACGTG 
GCCCTGAAGG TGGAGTCAGC CCAACAGCCT AAGCAGGTCC TCAAGATGGA GGTGGCTGTG 
CTCAAAAAGC TTCAAGGGAA GGACCACGTG TGCAGGTTCA TTGGCTGTGG CAGGAATGAG 
AAGTTTAACT ATGTGGTGAT GCAGCTCCAG GGTCGGAACC TGGCTGACTT GCGCCGCAGC 
CAGCCAAGGG GCACTTTCAC ACTGAGTACC ACACTGCGTC TGGGCAAGCA GATTCTGGAG 
TCCATTGAAG CCATTCACTC CGTGGGCTTC CTGCACCGTG ACATCAAGCC GTCCAACTTT 
GCCATGGGCC GGCTGCCCTC CACCTACAGA AAGTGCTACA TGTTGGACTT TGGGCTGGCC 
CGGCAGTACA CTAACACCAC TGGGGACGTC CGGCCTCCTC GGAATGTGGC CGGGTTCCGG 
GGGACTGTCC GCTACGCGTC GGTCAACGCT CACAAGAATC GGGAGATGGG CCGCCATGAT 
GACCTGTGGT CCCTCTTCTA CATGCTGGTG GAGTTTGCTG TGGGGCAGCT GCCCTGGAGG 
AAGATCAAGG ACAAGGAGCA GGTAGGGATG ATCAAGGAGA AGTATGAGCA CCGGATGCTA 
CTGAAGCACA TGCCTTCCGA GTTCCATCTC TTCCTGGACC ACATCGCCAG CCTCGACTAC 
TTCACCAAGC CCGACTACCA GTTGATCATG TCGGTGTTTG AGAACAGCAT GAAGGAACGG 
GGCATTGCTG AGAATGAGGC CTTTGACTGG GAGAAGGCAG GCACTGATGC CCTTCTGTCC 
ACGAGCACCT CCACCCCACC CCAGCAGAAC ACACGGCAGA CGGCAGCCAT GTTTGGAGTG 
GTCAATGTGA CACCTGTGCC CGGGGACCTG CTTCGTGAGA ACACTGAGGA TGTGCTCCAG 
GGAGAACACC TGAGTGACCA GGAGAATGCA CCCCCAATCC TGCCTGGGAG GCCTCCGGAG 
GGCTTGGGTC CTGGTCCCCA CCTTGTCCCC CACCCTGGGG GTCCTGAGGC TGAAGTGTGG 
GAGGAGACAG ATGTCAACCG TAACAAACTG CGCATCAACA TTGGCAAAAC ACCCTGTGTG 
GAAGAAGAGC AGAGTCGAGG AGTCGGGGTC CCCAGCTCCC CAGTGCGTGC TCCCCCAGAC 
TCCCCTACAA CCCCAGTGCG GTCTTTACGC TATCGGAGGG TCAATAGCCC AGAGTCGGAA 
AGGCTGTCTA CAGCAGCTGA TGGGCGGGCA GAACTTCAGG AGAGGAGGTC ACGGATGGAT 
CTGCCTGGCT CACCCTCACG CCAGGCCTGC TCCTCACAAC CAGCTCAGAT GCTGTCAGTG 
GACACAGGCC ATGCCGACAG GCAGGCCAGT GGCCGCATGG ACGTGTCAGC CTCTGTGGAG 
CAGGAGGCCC TGAGCAACGC CTTCCGCTCA GTGCCACTGG CTGAGGAGGA AGACTTTGAC 
AGCAAGGAGT GGGTCATTAT TGACAAGGAG ACAGAGCTCA AGGACTTCCC TCCTGGGGCT 
GAGCCCAGCA CATCAGGTAC CACAGATGAA GAACCTGAGG AGCTGCGGCC TTTGCCTGAG 
GAGGGCGAGG AGAGGAGGCG TCTGGGGACA GAGCCTACTG TCAGGCCTCG TGGACGTGGT 
ATGCAGACGC TGGCAGAGGA GGACCCACGG CAGATGCTGC CCCAGCCTGC ACCACCTCAG 
TTGAGCCAGG CTGATGGCCG GTCAGAGACA TCGCAGCCTC CCACGCCTGG CAGCCCTTCC 
CACTCACCCC TGCACTCGGG ACCCCGCCCT CGACGGAGAG AGTCGGATCC TACAGGCCCT 
CAGAGACAGG TGTTCTCTGT GGCGCCCCCG TTTGAGGTGA ATGGCCTTCC ACGAGCTGTG 
CCTCTGGGCT TGCCCTACCA GGACTTCAAG AGAGACCTCT CTGATTATCG AGAACGGGCC 
CGGCTGCTCA ACAGGGTCCG AAGGGTGGGC TTCTCGCACA TGCTGCTCAC CACACCGCAG 
GTCCCATTGG CTCCTTTCCA GCCTCAAGCC AATGGGAAAG AGGGTGAAGA GGAAGAGGAG 
GAGGATGAAG AGGAAGAGGA GGAAGAAGAG GAGGAAGATG AGGAAGACGA GGAGGAAGAG 
GATGAGGAAG ATGAAGATGA GGAGGAGGAG GAGGCAGGGG CTCTTGGGGA GGTGCTGGGG 
CCTCGAAGCG GCTCCAGCAG TGAGGGGAGT GAACGGAGCC AGGAGGGCGC CCCATCCACA 
CTGCTGGCTG ACGACCAGAA AGAGGCCAGG GGCCGGGCCT CCATGGCTGA TGGGGACCTG 
GAGCCTGAGG AGGGCTCCAA AACGCTGGTG CTCGTCTCCC CTGGTGACAT GAAGAAGTCA 
CCAGTCACTG CCGAACTGGC CCCTGACCCT GATCTGGGCA CCTTGGCTGC ACTCACCCCT 
CAGCACGAGC GGCCTCAGCC TACTGGAAGC CAGCTGGATG TGTCAGAGCC GGGCACCCTG 
TCCTCCATCC TCAAGTCTGA ACCCAAGCCC TCAGGACCTG GAGCAGGGGT TGGGGTTGGG 
CTGGTGGCCC CTGGGGCTGG GGTCACCGCA GTGACATCAC CCTTCACCAA AGTCGAAAGG 
ACCTTTGTTC ACATTGCAGA GAAATCCCAC CTCAATGTCA TGTCTTCCGG AGGACAGGCC 
CCCAGGCCAG AGGAGCTGAG CACTGGGGGC GAGTTGGGCC TAGAGATGCT CTCTGAGGTG 
GGCGCTGCAG AGGAGGGCGC CCCACAGCCT CTGGAGAACG GCATGGCTTT GGTAGGCCCG 
GATGGGACGG AGATGGAAAG TTGTGCCCTG TCTGGCCCTC CTGGGGAGAC ACCCTCAGAA 
GTAGTCACAG ACTCATTGCC CGATGGCCCA GCCCTTGCCG ATGAACCGGC TCCAGCATCC 
CCACAAGAGC CAATAACCAA GAAAGGGACC ATCATCTCCC CCAGCCGCCA TGCCATGCCA 
GGATCTCGCC CCAGGAGCCG CATTCCTGTC TTGTTGTCTG AAGAGGACAC AGGCTCAGAG 
CCTTCGGGCT CACTGTCGGC CAAAGAGCGG TGGAGCAAGA GGGCTCGGCC ACAGCAGGAT 
CTGGCTCGCC TCGTGATGGA GAAGAGGCAG GGTCGGCTAC TGCTGCGGCT GGCCTCAGGG 
GCCTCCTCCT CCTCCAGCGA GGAGCAGCGC CGTGCCTCTG AGACACTCTC AGGCACCGGC 
TCCGAGGAGG ACACGCCTGC CTCAGAGCCT GCAGCAGCCT TGCCTAGGAA GGCTGGGCGG 
GCAGCGACCA CCCGGAGCCG GATCCCCCGC CCCATCAGTG TGTCCATGCC TGCAGAAGGC 
CAGCAGCTTC CTGGTAGACC CCACGGTGCG GCCTCAGCGA CCGACTCGGC CATCACCAGC 
AGGCTCCAGC TGCAGAAGCC CCCAGGGTTG GCCACTGCTG CTGACCACCG TCCCAAACAG 
CCCGCAAGCC GGGCTTCCGG CCCAGGTCGC GCCCAAGTCT CCAAGCCCGC AGCACCCCGC 
AGTCCCGGCC TCCCCACCTC CACCGCGCGC CACTCCAGCG GGTCCCCGCG GAGCCAGTCC 
CTGTCCCGCA AAGAGAGCTC CTCCCCCTCG CATCAAGCCC GGCCTGGTTT CCCTCCATCT 
CGGGGGGTCC TCCAAGTCAG ATCTCAGTCG GAGGCCTCCC CGGGGGGCCC CAAGAAAGGA 
CCCAAGGGGA AACAACTGCA GACTCTGCGC GCAGCAACCA AAGGCCGGCC GGCGGTTTCA 
GAGGGTCGGC CCGGGAACAG ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001258159.1
CDS	1..3924
Translation	MQCLAAALKDETNMSGGGEQADILPANYVVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNTTGDVRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGMIKEKYEHRMLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGIAENEAFDWEKAGTDALLSTSTSTPPQQNTRQTAAMFGVVNVTPVPGDLLRENTEDVLQGEHLSDQENAPPILPGRPPEGLGPGPHLVPHPGGPEAEVWEETDVNRNKLRINIGKTPCVEEEQSRGVGVPSSPVRAPPDSPTTPVRSLRYRRVNSPESERLSTAADGRAELQERRSRMDLPGSPSRQACSSQPAQMLSVDTGHADRQASGRMDVSASVEQEALSNAFRSVPLAEEEDFDSKEWVIIDKETELKDFPPGAEPSTSGTTDEEPEELRPLPEEGEERRRLGTEPTVRPRGRGMQTLAEEDPRQMLPQPAPPQLSQADGRSETSQPPTPGSPSHSPLHSGPRPRRRESDPTGPQRQVFSVAPPFEVNGLPRAVPLGLPYQDFKRDLSDYRERARLLNRVRRVGFSHMLLTTPQVPLAPFQPQANGKEGEEEEEEDEEEEEEEEEEDEEDEEEEDEEDEDEEEEEAGALGEVLGPRSGSSSEGSERSQEGAPSTLLADDQKEARGRASMADGDLEPEEGSKTLVLVSPGDMKKSPVTAELAPDPDLGTLAALTPQHERPQPTGSQLDVSEPGTLSSILKSEPKPSGPGAGVGVGLVAPGAGVTAVTSPFTKVERTFVHIAEKSHLNVMSSGGQAPRPEELSTGGELGLEMLSEVGAAEEGAPQPLENGMALVGPDGTEMESCALSGPPGETPSEVVTDSLPDGPALADEPAPASPQEPITKKGTIISPSRHAMPGSRPRSRIPVLLSEEDTGSEPSGSLSAKERWSKRARPQQDLARLVMEKRQGRLLLRLASGASSSSSEEQRRASETLSGTGSEEDTPASEPAAALPRKAGRAATTRSRIPRPISVSMPAEGQQLPGRPHGAASATDSAITSRLQLQKPPGLATAADHRPKQPASRASGPGRAQVSKPAAPRSPGLPTSTARHSSGSPRSQSLSRKESSSPSHQARPGFPPSRGVLQVRSQSEASPGGPKKGPKGKQLQTLRAATKGRPAVSEGRPGNR

Target ORF information:

RefSeq Version	NM_001271230.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus tau tubulin kinase 1 (Ttbk1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001271230.1

ORF Insert Sequence:

ATGCAGTGCC TAGCGGCTGC TCTTAAAGAC GAAACCAACA TGAGTGGGGG AGGGGAGCAG 
GCCGACATCC TGCCGGCCAA CTACGTGGTC AAAGATCGCT GGAAGGTGCT GAAAAAGATC 
GGGGGCGGGG GCTTCGGTGA GATCTATGAG GCCATGGACC TGCTGACCAG GGAGAACGTG 
GCCCTGAAGG TGGAGTCAGC CCAACAGCCT AAGCAGGTCC TCAAGATGGA GGTGGCTGTG 
CTCAAAAAGC TTCAAGGGAA GGACCACGTG TGCAGGTTCA TTGGCTGTGG CAGGAATGAG 
AAGTTTAACT ATGTGGTGAT GCAGCTCCAG GGTCGGAACC TGGCTGACTT GCGCCGCAGC 
CAGCCAAGGG GCACTTTCAC ACTGAGTACC ACACTGCGTC TGGGCAAGCA GATTCTGGAG 
TCCATTGAAG CCATTCACTC CGTGGGCTTC CTGCACCGTG ACATCAAGCC GTCCAACTTT 
GCCATGGGCC GGCTGCCCTC CACCTACAGA AAGTGCTACA TGTTGGACTT TGGGCTGGCC 
CGGCAGTACA CTAACACCAC TGGGGACGTC CGGCCTCCTC GGAATGTGGC CGGGTTCCGG 
GGGACTGTCC GCTACGCGTC GGTCAACGCT CACAAGAATC GGGAGATGGG CCGCCATGAT 
GACCTGTGGT CCCTCTTCTA CATGCTGGTG GAGTTTGCTG TGGGGCAGCT GCCCTGGAGG 
AAGATCAAGG ACAAGGAGCA GGTAGGGATG ATCAAGGAGA AGTATGAGCA CCGGATGCTA 
CTGAAGCACA TGCCTTCCGA GTTCCATCTC TTCCTGGACC ACATCGCCAG CCTCGACTAC 
TTCACCAAGC CCGACTACCA GTTGATCATG TCGGTGTTTG AGAACAGCAT GAAGGAACGG 
GGCATTGCTG AGAATGAGGC CTTTGACTGG GAGAAGGCAG GCACTGATGC CCTTCTGTCC 
ACGAGCACCT CCACCCCACC CCAGCAGAAC ACACGGCAGA CGGCAGCCAT GTTTGGAGTG 
GTCAATGTGA CACCTGTGCC CGGGGACCTG CTTCGTGAGA ACACTGAGGA TGTGCTCCAG 
GGAGAACACC TGAGTGACCA GGAGAATGCA CCCCCAATCC TGCCTGGGAG GCCTCCGGAG 
GGCTTGGGTC CTGGTCCCCA CCTTGTCCCC CACCCTGGGG GTCCTGAGGC TGAAGTGTGG 
GAGGAGACAG ATGTCAACCG TAACAAACTG CGCATCAACA TTGGCAAAAC ACCCTGTGTG 
GAAGAAGAGC AGAGTCGAGG AGTCGGGGTC CCCAGCTCCC CAGTGCGTGC TCCCCCAGAC 
TCCCCTACAA CCCCAGTGCG GTCTTTACGC TATCGGAGGG TCAATAGCCC AGAGTCGGAA 
AGGCTGTCTA CAGCAGCTGA TGGGCGGGCA GAACTTCAGG AGAGGAGGTC ACGGATGGAT 
CTGCCTGGCT CACCCTCACG CCAGGCCTGC TCCTCACAAC CAGCTCAGAT GCTGTCAGTG 
GACACAGGCC ATGCCGACAG GCAGGCCAGT GGCCGCATGG ACGTGTCAGC CTCTGTGGAG 
CAGGAGGCCC TGAGCAACGC CTTCCGCTCA GTGCCACTGG CTGAGGAGGA AGACTTTGAC 
AGCAAGGAGT GGGTCATTAT TGACAAGGAG ACAGAGCTCA AGGACTTCCC TCCTGGGGCT 
GAGCCCAGCA CATCAGGTAC CACAGATGAA GAACCTGAGG AGCTGCGGCC TTTGCCTGAG 
GAGGGCGAGG AGAGGAGGCG TCTGGGGACA GAGCCTACTG TCAGGCCTCG TGGACGTGGT 
ATGCAGACGC TGGCAGAGGA GGACCCACGG CAGATGCTGC CCCAGCCTGC ACCACCTCAG 
TTGAGCCAGG CTGATGGCCG GTCAGAGACA TCGCAGCCTC CCACGCCTGG CAGCCCTTCC 
CACTCACCCC TGCACTCGGG ACCCCGCCCT CGACGGAGAG AGTCGGATCC TACAGGCCCT 
CAGAGACAGG TGTTCTCTGT GGCGCCCCCG TTTGAGGTGA ATGGCCTTCC ACGAGCTGTG 
CCTCTGGGCT TGCCCTACCA GGACTTCAAG AGAGACCTCT CTGATTATCG AGAACGGGCC 
CGGCTGCTCA ACAGGGTCCG AAGGGTGGGC TTCTCGCACA TGCTGCTCAC CACACCGCAG 
GTCCCATTGG CTCCTTTCCA GCCTCAAGCC AATGGGAAAG AGGGTGAAGA GGAAGAGGAG 
GAGGATGAAG AGGAAGAGGA GGAAGAAGAG GAGGAAGATG AGGAAGACGA GGAGGAAGAG 
GATGAGGAAG ATGAAGATGA GGAGGAGGAG GAGGCAGGGG CTCTTGGGGA GGTGCTGGGG 
CCTCGAAGCG GCTCCAGCAG TGAGGGGAGT GAACGGAGCC AGGAGGGCGC CCCATCCACA 
CTGCTGGCTG ACGACCAGAA AGAGGCCAGG GGCCGGGCCT CCATGGCTGA TGGGGACCTG 
GAGCCTGAGG AGGGCTCCAA AACGCTGGTG CTCGTCTCCC CTGGTGACAT GAAGAAGTCA 
CCAGTCACTG CCGAACTGGC CCCTGACCCT GATCTGGGCA CCTTGGCTGC ACTCACCCCT 
CAGCACGAGC GGCCTCAGCC TACTGGAAGC CAGCTGGATG TGTCAGAGCC GGGCACCCTG 
TCCTCCATCC TCAAGTCTGA ACCCAAGCCC TCAGGACCTG GAGCAGGGGT TGGGGTTGGG 
CTGGTGGCCC CTGGGGCTGG GGTCACCGCA GTGACATCAC CCTTCACCAA AGTCGAAAGG 
ACCTTTGTTC ACATTGCAGA GAAATCCCAC CTCAATGTCA TGTCTTCCGG AGGACAGGCC 
CCCAGGCCAG AGGAGCTGAG CACTGGGGGC GAGTTGGGCC TAGAGATGCT CTCTGAGGTG 
GGCGCTGCAG AGGAGGGCGC CCCACAGCCT CTGGAGAACG GCATGGCTTT GGTAGGCCCG 
GATGGGACGG AGATGGAAAG TTGTGCCCTG TCTGGCCCTC CTGGGGAGAC ACCCTCAGAA 
GTAGTCACAG ACTCATTGCC CGATGGCCCA GCCCTTGCCG ATGAACCGGC TCCAGCATCC 
CCACAAGAGC CAATAACCAA GAAAGGGACC ATCATCTCCC CCAGCCGCCA TGCCATGCCA 
GGATCTCGCC CCAGGAGCCG CATTCCTGTC TTGTTGTCTG AAGAGGACAC AGGCTCAGAG 
CCTTCGGGCT CACTGTCGGC CAAAGAGCGG TGGAGCAAGA GGGCTCGGCC ACAGCAGGAT 
CTGGCTCGCC TCGTGATGGA GAAGAGGCAG GGTCGGCTAC TGCTGCGGCT GGCCTCAGGG 
GCCTCCTCCT CCTCCAGCGA GGAGCAGCGC CGTGCCTCTG AGACACTCTC AGGCACCGGC 
TCCGAGGAGG ACACGCCTGC CTCAGAGCCT GCAGCAGCCT TGCCTAGGAA GGCTGGGCGG 
GCAGCGACCA CCCGGAGCCG GATCCCCCGC CCCATCAGTG TGTCCATGCC TGCAGAAGGC 
CAGCAGCTTC CTGGTAGACC CCACGGTGCG GCCTCAGCGA CCGACTCGGC CATCACCAGC 
AGGCTCCAGC TGCAGAAGCC CCCAGGGTTG GCCACTGCTG CTGACCACCG TCCCAAACAG 
CCCGCAAGCC GGGCTTCCGG CCCAGGTCGC GCCCAAGTCT CCAAGCCCGC AGCACCCCGC 
AGTCCCGGCC TCCCCACCTC CACCGCGCGC CACTCCAGCG GGTCCCCGCG GAGCCAGTCC 
CTGTCCCGCA AAGAGAGCTC CTCCCCCTCG CATCAAGCCC GGCCTGGTTT CCCTCCATCT 
CGGGGGGTCC TCCAAGTCAG ATCTCAGTCG GAGGCCTCCC CGGGGGGCCC CAAGAAAGGA 
CCCAAGGGGA AACAACTGCA GACTCTGCGC GCAGCAACCA AAGGCCGGCC GGCGGTTTCA 
GAGGGTCGGC CCGGGAACAG ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

TTBK2 with EB1/3 regulates microtubule dynamics in migrating cells through KIF2A phosphorylation.
The Journal of cell biology210(5)737-51(2015 Aug)
Watanabe T,Kakeno M,Matsui T,Sugiyama I,Arimura N,Matsuzawa K,Shirahige A,Ishidate F,Nishioka T,Taya S,Hoshino M,Kaibuchi K

Quantitative proteomic analysis of human substantia nigra in Alzheimer's disease, Huntington's disease and Multiple sclerosis.
Neurochemical research37(12)2805-13(2012 Dec)
Chen S,Lu FF,Seeman P,Liu F

Spatial learning impairment, enhanced CDK5/p35 activity, and downregulation of NMDA receptor expression in transgenic mice expressing tau-tubulin kinase 1.
The Journal of neuroscience : the official journal of the Society for Neuroscience28(53)14511-21(2008 Dec)
Sato S,Xu J,Okuyama S,Martinez LB,Walsh SM,Jacobsen MT,Swan RJ,Schlautman JD,Ciborowski P,Ikezu T

Tau-tubulin kinase 1 (TTBK1), a neuron-specific tau kinase candidate, is involved in tau phosphorylation and aggregation.
Journal of neurochemistry98(5)1573-84(2006 Sep)
Sato S,Cerny RL,Buescher JL,Ikezu T

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Ttbk1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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