The following Pragmin gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pragmin cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa03273 | |
| Clone ID Related Accession (Same CDS sequence) | XM_017600132.1 , NM_001107315.1 , XM_017600131.1 | |
| Accession Version | NM_001107315.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 4107bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-26 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | inactive tyrosine-protein kinase PRAG1 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CH473970.2. On or before Oct 4, 2007 this sequence version replaced XM_001066723.1, XM_224908.4. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMD00052296, SAMN01906348 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGTCTGCGT GCAGTGACTT TGTGGAGCAC ATCTGGAAAC CCGGATCCTG CAAGAACTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001100785.1 |
| CDS | 263..4369 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001107315.1 |
1 | ATGTCTGCGT GCAGTGACTT TGTGGAGCAC ATCTGGAAAC CCGGATCCTG CAAGAACTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa03273 | |
| Clone ID Related Accession (Same CDS sequence) | XM_017600132.1 , NM_001107315.1 , XM_017600131.1 | |
| Accession Version | XM_017600132.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 4107bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-07-25 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | tyrosine-protein kinase SgK223 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005115.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGTCTGCGT GCAGTGACTT TGTGGAGCAC ATCTGGAAAC CCGGATCCTG CAAGAACTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_017455621.1 |
| CDS | 244..4350 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_017600132.1 |
1 | ATGTCTGCGT GCAGTGACTT TGTGGAGCAC ATCTGGAAAC CCGGATCCTG CAAGAACTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa03273 | |
| Clone ID Related Accession (Same CDS sequence) | XM_017600132.1 , NM_001107315.1 , XM_017600131.1 | |
| Accession Version | XM_017600131.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 4107bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-07-25 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | tyrosine-protein kinase SgK223 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005115.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGTCTGCGT GCAGTGACTT TGTGGAGCAC ATCTGGAAAC CCGGATCCTG CAAGAACTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_017455620.1 |
| CDS | 299..4405 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_017600131.1 |
1 | ATGTCTGCGT GCAGTGACTT TGTGGAGCAC ATCTGGAAAC CCGGATCCTG CAAGAACTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Structure of SgK223 pseudokinase reveals novel mechanisms of homotypic and heterotypic association. |
C-terminal Src kinase-mediated EPIYA phosphorylation of Pragmin creates a feed-forward C-terminal Src kinase activation loop that promotes cell motility. |
NACK is an integral component of the Notch transcriptional activation complex and is critical for development and tumorigenesis. |
Mammalian Pragmin regulates Src family kinases via the Glu-Pro-Ile-Tyr-Ala (EPIYA) motif that is exploited by bacterial effectors. |
