Iqub cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Iqub
Entrez Gene ID	296936
Full Name	IQ motif and ubiquitin domain containing
Synonyms	RGD1562359,Trs4
General protein information	Preferred Names IQ motif and ubiquitin domain containing Names IQ and ubiquitin-like domain-containing protein
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 4 Map Location: 4q22

mRNA and Protein(s)

mRNA	Protein	Name
NM_001034130.1	NP_001029302.1	IQ and ubiquitin-like domain-containing protein

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	IQUB	XP_001147235.2
Danio rerio (zebrafish)	LOC100334576	XP_002666923.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP002068	XP_320979.2
Bos taurus (cattle)	LOC536449	NP_001193878.1
Gallus gallus (chicken)	IQUB	XP_004937583.1
	IQUB	XP_001085476.1
Canis lupus familiaris (dog)	IQUB	XP_005628832.1
Mus musculus (house mouse)	Iqub	NP_766123.2
Homo sapiens (human)	IQUB	NP_849149.3
Rattus norvegicus (Norway rat)	Iqub	NP_001029302.1
Drosophila melanogaster (fruit fly)	CG13855	NP_651037.1
Xenopus tropicalis (tropical clawed frog)	iqub	XP_004913050.1

Gene Ontology
Bibliography

Related articles in PubMed

Functional characterization of putative cilia genes by high-content analysis.
Lai CK, Gupta N, Wen X, Rangell L, Chih B, Peterson AS, Bazan JF, Li L, Scales SJ
Molecular biology of the cell22(7)1104-19(2011 Apr)

Male germ cell-specific protein Trs4 binds to multiple proteins.
Shi YQ, Li YC, Hu XQ, Liu T, Liao SY, Guo J, Huang L, Hu ZY, Tang AY, Lee KF, Yeung WS, Han CS, Liu YX
Biochemical and biophysical research communications388(3)583-8(2009 Oct)

Sorting nexin 9 interacts with dynamin 1 and N-WASP and coordinates synaptic vesicle endocytosis.
Shin N, Lee S, Ahn N, Kim SA, Ahn SG, YongPark Z, Chang S
The Journal of biological chemistry282(39)28939-50(2007 Sep)

An NGF-induced Exo70-TC10 complex locally antagonises Cdc42-mediated activation of N-WASP to modulate neurite outgrowth.
Pommereit D, Wouters FS
Journal of cell science120(Pt 15)2694-705(2007 Aug)

Identification of N-WASP homologs in human and rat brain.
Fukuoka M, Miki H, Takenawa T
Gene196(1-2)43-8(1997 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These results suggested that Trs4 might be involved in diverse processes of spermiogenesis and/or fertilization through interactions with its multiple binding partners.
Title: Male germ cell-specific protein Trs4 binds to multiple proteins.

SNX9 interacts with dynamin-1 and N-WASP in presynaptic terminals, where it links actin dynamics and synaptic vesicle endocytosis.
Title: Sorting nexin 9 interacts with dynamin 1 and N-WASP and coordinates synaptic vesicle endocytosis.

findings confirm that the Exo70-TC10 complex mainly targets the NGF-induced Cdc42-dependent activation of N-WASP
Title: An NGF-induced Exo70-TC10 complex locally antagonises Cdc42-mediated activation of N-WASP to modulate neurite outgrowth.

The following Iqub gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Iqub cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa08586	NM_001034130.1 Latest version!	Rattus norvegicus IQ motif and ubiquitin domain containing (Iqub), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$461.30 $659.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Iqub ( NM_001034130.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001029302.1 Rattus norvegicus IQ motif and ubiquitin domain containing (Iqub), mRNA.

Price & Availability↑

CloneID	ORa08586
Clone ID Related Accession (Same CDS sequence)	NM_001034130.1
Accession Version	NM_001034130.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2373bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-19
Organism	Rattus norvegicus(Norway rat)
Product	IQ and ubiquitin-like domain-containing protein
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC099086.1. On Oct 14, 2005 this sequence version replaced XM_342648.2. ##Evidence-Data-START## Transcript exon combination :: BC099086.1, DQ132434.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN02642719 [ECO:0000348] ##Evidence-Data-END##

ATGTCCGATA CGGAGGAGAA TGTCCTTGAC TCCCCGGCCA GTGGTGAAGC GGCCGGCGAA 
GTCATCAGTA TTCCTGGCCC TACAGACGAA GCAGAAGAGT CAGATATCTC ACCAGAGCAA 
GAATACGAAA TAGAGGGATT TACCACCGAG AGTGAGGAGA CAGTGGAGCA CTACAGTGAT 
CTCAGTGTTT CAACCCCCAA ATCTTACGAC TCCAAACCCA GGGACGAGGT CGTGTCCCTT 
GGAAGTGCCA CAGACTCTCA TGAGCAAGAA TACAGACTTG GAGATCTTGG AGGTGACCAG 
AGATCAGAAG AGGACGAGAT GTCATTTCTT TATAAAATCA AAGCTATAAA GGAGAACTTG 
CAGTCGTCAG TGAAAGAGTG TATAGCCACA GTAAAAATTG TACTTATTCC TGCAGGCCAG 
GAAATTGTAA TGCCTTTCAG AGTTGATGCT CCATTTAGAT TCCTCAAGGA GCACTTTGCA 
CACTTATTAC GTATCCCCCA TCATGTATTG CAAATGGCCT ATACAGGAAT CAGTGTTGGG 
AATAATGAGT CCCTGATACA ATATGGAGTC AAACCACGGG AAATCGTTCA AATGAATGTA 
TTTTCCTCAG AACCCGACCA ATATCCAGTC AGAAGAATAG AGGGCTTGAG TGAGGGCTCC 
AAGATCATAA CGGTCACCAT TCAGACCGGC ATCGAACGCT ACGAGGAGGT AGCTGTGGAG 
ATAGTAAAAT CTGACTTCCA CAAGCCATTT CTTGGTGGAT TTAGACATAA AATAACAGGA 
CTAGAATACC ACAATGCTGG GACACAAACT GTACCCAAGA AGATTCCGGA AAAAGACAAT 
CTGTTCTGTA GGGACACCCA GACAGTTTTT CAGAAAAAGA AGCTGCAACA AACTATGAAT 
ACCACCTCCA CTCAGATGAC TAAAATCGGT GTATACGTAT CAAACATGAC TGATAAACTG 
CTCACGCCAG GAAGTTACTT TTCAGCTGCA GAGTACCACG CTCGAAGGTT GAACGCGGTG 
ATAGTGATTC AGACTGCCTA CAGGCGATGG CACGCTAAGT GCTATGTCGA CAGCCTAAGA 
CTACAAAAGA AAATGAGGTT GGAGTGGGAA AAAGAGGAAG AACTTAAGAA GATCCGAGAG 
AAGGAAGAAT GGATACGAAT GGACTATTAC CGGAGGCACA ATCCTAAAAC AACCGAAGAC 
TTTGAGCTCC TTTTCAATGC TCTAGAACTT TGGCGTCAAG AAGAAGTCAC ACAAGTTGAG 
CAATATTCAA GTGAGGCTGA AAGGAAAGCT GCTCTGTGCG AGCTTTTGGA AAAAGAGACG 
CAGATAATTG CTTCCATCGG GAGACATAGA TACGTTGCTC AGTTGGAGAG ACAGGATGTA 
GCTACACAAG CTTTTCTGGA TAAGTGTTCA GCTTCAAATA CCTGGAGAAG ACCTGATGGA 
CAAACCGTTG AAATGGACAC ACAGTTCACA ATAAGAGCCA GAGAGCTGCA AAGCATCTAC 
AAGTGTATCC TGCTGAAAAA CCTCTCTCAA GATGAGAGGC TGGATATACT CCTGACACTG 
AAGCACACTG TGAAGGAACA TGAGTGTAAA CTGACCCAAG AAATCCTAGA ATTGATTGAC 
AGAGAAGTTG ACCTTATGAT GAGAGGAGTT AAATCTCATA ATCTCGAAGG ACTCAGGAAA 
AGAATCACAA CACTCTTTAT TCACTATATC AAAACTCCTC TGTTTAACCC AGAAGTCGCA 
AAACACCTTA AGGTCCCTCA AGACCCACTG AAGTTTTATG ATAAGATTTA CTTCTGCCAC 
AGTTGCCAAA TGTATTTGCC TTCTGTCGAG TTTTCCGTCT CACCCACCTC GCATCGTGTG 
TACCGCTGCC GGCACTGCAT AAACCTGGAG AATGAGACTC AGAGGCGGGA ATCATTTTTG 
AAATACAAGT GTTTACTTCA GCGGCTCTAC TTCTCAGAAG CCAATTATGA GGATAACTCC 
CACATTGCTT ATCTAATGCA GCTTCAGGAT ATTAAGTACT TGACAGAGAA CATCTGGGCA 
TCGCAGTCGG CCCTCAGCGC CTGGGATGAC CTCAATGACC TGGTCATGGT CAGGTGGAAC 
AAACACGTGG AGTGGTCGCC CTGGAACTGC ATTCTGCTCA CCAAGGATGA AGGCACAGCT 
CATCTCAAGC TAGAGAGCAT CGAGAAGGGA TATGGACGCC TTTTTATTCA CAAGATCAAG 
CACAAACATA TCTTGGCTAA AAACTATTTT TCACAGGTCC CAGTGCTGGC TTCACTTATA 
CTTAAGGATG ATGAAATAGA AGCTATCAGA AGTAAATACT CCACAGAGAA TCCTCCTAAA 
ATCATAGTAC CCCATGGGAT TGTACCTAAT TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001029302.1
CDS	50..2422
Translation	MSDTEENVLDSPASGEAAGEVISIPGPTDEAEESDISPEQEYEIEGFTTESEETVEHYSDLSVSTPKSYDSKPRDEVVSLGSATDSHEQEYRLGDLGGDQRSEEDEMSFLYKIKAIKENLQSSVKECIATVKIVLIPAGQEIVMPFRVDAPFRFLKEHFAHLLRIPHHVLQMAYTGISVGNNESLIQYGVKPREIVQMNVFSSEPDQYPVRRIEGLSEGSKIITVTIQTGIERYEEVAVEIVKSDFHKPFLGGFRHKITGLEYHNAGTQTVPKKIPEKDNLFCRDTQTVFQKKKLQQTMNTTSTQMTKIGVYVSNMTDKLLTPGSYFSAAEYHARRLNAVIVIQTAYRRWHAKCYVDSLRLQKKMRLEWEKEEELKKIREKEEWIRMDYYRRHNPKTTEDFELLFNALELWRQEEVTQVEQYSSEAERKAALCELLEKETQIIASIGRHRYVAQLERQDVATQAFLDKCSASNTWRRPDGQTVEMDTQFTIRARELQSIYKCILLKNLSQDERLDILLTLKHTVKEHECKLTQEILELIDREVDLMMRGVKSHNLEGLRKRITTLFIHYIKTPLFNPEVAKHLKVPQDPLKFYDKIYFCHSCQMYLPSVEFSVSPTSHRVYRCRHCINLENETQRRESFLKYKCLLQRLYFSEANYEDNSHIAYLMQLQDIKYLTENIWASQSALSAWDDLNDLVMVRWNKHVEWSPWNCILLTKDEGTAHLKLESIEKGYGRLFIHKIKHKHILAKNYFSQVPVLASLILKDDEIEAIRSKYSTENPPKIIVPHGIVPN

Target ORF information:

RefSeq Version	NM_001034130.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus IQ motif and ubiquitin domain containing (Iqub), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001034130.1

ORF Insert Sequence:

ATGTCCGATA CGGAGGAGAA TGTCCTTGAC TCCCCGGCCA GTGGTGAAGC GGCCGGCGAA 
GTCATCAGTA TTCCTGGCCC TACAGACGAA GCAGAAGAGT CAGATATCTC ACCAGAGCAA 
GAATACGAAA TAGAGGGATT TACCACCGAG AGTGAGGAGA CAGTGGAGCA CTACAGTGAT 
CTCAGTGTTT CAACCCCCAA ATCTTACGAC TCCAAACCCA GGGACGAGGT CGTGTCCCTT 
GGAAGTGCCA CAGACTCTCA TGAGCAAGAA TACAGACTTG GAGATCTTGG AGGTGACCAG 
AGATCAGAAG AGGACGAGAT GTCATTTCTT TATAAAATCA AAGCTATAAA GGAGAACTTG 
CAGTCGTCAG TGAAAGAGTG TATAGCCACA GTAAAAATTG TACTTATTCC TGCAGGCCAG 
GAAATTGTAA TGCCTTTCAG AGTTGATGCT CCATTTAGAT TCCTCAAGGA GCACTTTGCA 
CACTTATTAC GTATCCCCCA TCATGTATTG CAAATGGCCT ATACAGGAAT CAGTGTTGGG 
AATAATGAGT CCCTGATACA ATATGGAGTC AAACCACGGG AAATCGTTCA AATGAATGTA 
TTTTCCTCAG AACCCGACCA ATATCCAGTC AGAAGAATAG AGGGCTTGAG TGAGGGCTCC 
AAGATCATAA CGGTCACCAT TCAGACCGGC ATCGAACGCT ACGAGGAGGT AGCTGTGGAG 
ATAGTAAAAT CTGACTTCCA CAAGCCATTT CTTGGTGGAT TTAGACATAA AATAACAGGA 
CTAGAATACC ACAATGCTGG GACACAAACT GTACCCAAGA AGATTCCGGA AAAAGACAAT 
CTGTTCTGTA GGGACACCCA GACAGTTTTT CAGAAAAAGA AGCTGCAACA AACTATGAAT 
ACCACCTCCA CTCAGATGAC TAAAATCGGT GTATACGTAT CAAACATGAC TGATAAACTG 
CTCACGCCAG GAAGTTACTT TTCAGCTGCA GAGTACCACG CTCGAAGGTT GAACGCGGTG 
ATAGTGATTC AGACTGCCTA CAGGCGATGG CACGCTAAGT GCTATGTCGA CAGCCTAAGA 
CTACAAAAGA AAATGAGGTT GGAGTGGGAA AAAGAGGAAG AACTTAAGAA GATCCGAGAG 
AAGGAAGAAT GGATACGAAT GGACTATTAC CGGAGGCACA ATCCTAAAAC AACCGAAGAC 
TTTGAGCTCC TTTTCAATGC TCTAGAACTT TGGCGTCAAG AAGAAGTCAC ACAAGTTGAG 
CAATATTCAA GTGAGGCTGA AAGGAAAGCT GCTCTGTGCG AGCTTTTGGA AAAAGAGACG 
CAGATAATTG CTTCCATCGG GAGACATAGA TACGTTGCTC AGTTGGAGAG ACAGGATGTA 
GCTACACAAG CTTTTCTGGA TAAGTGTTCA GCTTCAAATA CCTGGAGAAG ACCTGATGGA 
CAAACCGTTG AAATGGACAC ACAGTTCACA ATAAGAGCCA GAGAGCTGCA AAGCATCTAC 
AAGTGTATCC TGCTGAAAAA CCTCTCTCAA GATGAGAGGC TGGATATACT CCTGACACTG 
AAGCACACTG TGAAGGAACA TGAGTGTAAA CTGACCCAAG AAATCCTAGA ATTGATTGAC 
AGAGAAGTTG ACCTTATGAT GAGAGGAGTT AAATCTCATA ATCTCGAAGG ACTCAGGAAA 
AGAATCACAA CACTCTTTAT TCACTATATC AAAACTCCTC TGTTTAACCC AGAAGTCGCA 
AAACACCTTA AGGTCCCTCA AGACCCACTG AAGTTTTATG ATAAGATTTA CTTCTGCCAC 
AGTTGCCAAA TGTATTTGCC TTCTGTCGAG TTTTCCGTCT CACCCACCTC GCATCGTGTG 
TACCGCTGCC GGCACTGCAT AAACCTGGAG AATGAGACTC AGAGGCGGGA ATCATTTTTG 
AAATACAAGT GTTTACTTCA GCGGCTCTAC TTCTCAGAAG CCAATTATGA GGATAACTCC 
CACATTGCTT ATCTAATGCA GCTTCAGGAT ATTAAGTACT TGACAGAGAA CATCTGGGCA 
TCGCAGTCGG CCCTCAGCGC CTGGGATGAC CTCAATGACC TGGTCATGGT CAGGTGGAAC 
AAACACGTGG AGTGGTCGCC CTGGAACTGC ATTCTGCTCA CCAAGGATGA AGGCACAGCT 
CATCTCAAGC TAGAGAGCAT CGAGAAGGGA TATGGACGCC TTTTTATTCA CAAGATCAAG 
CACAAACATA TCTTGGCTAA AAACTATTTT TCACAGGTCC CAGTGCTGGC TTCACTTATA 
CTTAAGGATG ATGAAATAGA AGCTATCAGA AGTAAATACT CCACAGAGAA TCCTCCTAAA 
ATCATAGTAC CCCATGGGAT TGTACCTAAT TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Functional characterization of putative cilia genes by high-content analysis.
Molecular biology of the cell22(7)1104-19(2011 Apr)
Lai CK,Gupta N,Wen X,Rangell L,Chih B,Peterson AS,Bazan JF,Li L,Scales SJ

Male germ cell-specific protein Trs4 binds to multiple proteins.
Biochemical and biophysical research communications388(3)583-8(2009 Oct)
Shi YQ,Li YC,Hu XQ,Liu T,Liao SY,Guo J,Huang L,Hu ZY,Tang AY,Lee KF,Yeung WS,Han CS,Liu YX

Sorting nexin 9 interacts with dynamin 1 and N-WASP and coordinates synaptic vesicle endocytosis.
The Journal of biological chemistry282(39)28939-50(2007 Sep)
Shin N,Lee S,Ahn N,Kim SA,Ahn SG,YongPark Z,Chang S

An NGF-induced Exo70-TC10 complex locally antagonises Cdc42-mediated activation of N-WASP to modulate neurite outgrowth.
Journal of cell science120(Pt 15)2694-705(2007 Aug)
Pommereit D,Wouters FS

Identification of N-WASP homologs in human and rat brain.
Gene196(1-2)43-8(1997 Sep)
Fukuoka M,Miki H,Takenawa T

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Iqub cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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