Htr2b cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Htr2b
Entrez Gene ID	29581
Full Name	5-hydroxytryptamine receptor 2B
General protein information	Preferred Names 5-hydroxytryptamine receptor 2B Names 5-hydroxytryptamine receptor 2B 5-HT-2B 5-HT-2F 5-HT2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled serotonin receptor 2B stomach fundus serotonin receptor
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 9 Map Location: 9q35
Summary	G-protein coupled receptor for serotonin [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_017250.1	NP_058946.1	5-hydroxytryptamine receptor 2B
XM_017596306.1	XP_017451795.1	5-hydroxytryptamine receptor 2B isoform X1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	HTR2B	NP_001019804.1
Gallus gallus (chicken)	HTR2B	XP_004943419.1
Homo sapiens (human)	HTR2B	NP_000858.3
Pan troglodytes (chimpanzee)	HTR2B	XP_001144172.1
Bos taurus (cattle)	HTR2B	NP_001192377.1
Mus musculus (house mouse)	Htr2b	NP_032337.2
Rattus norvegicus (Norway rat)	Htr2b	NP_058946.1
Danio rerio (zebrafish)	htr2b	NP_001038208.1
Xenopus tropicalis (tropical clawed frog)	htr2b	XP_004914439.1
	HTR2B	XP_001113095.1

Gene Ontology
Bibliography

Related articles in PubMed

Serotonin 5-HT2B Receptor-Stimulated DNA Synthesis and Proliferation Are Mediated by Autocrine Secretion of Transforming Growth Factor-? in Primary Cultures of Adult Rat Hepatocytes.
Naito K, Moteki H, Kimura M, Natsume H, Ogihara M
Biological & pharmaceutical bulletin39(4)570-7(2016)

5-HT2B receptor blockade attenuates ?-adrenergic receptor-stimulated myocardial remodeling in rats via inhibiting apoptosis: role of MAPKs and HSPs.
Bharti S, Rani N, Bhatia J, Arya DS
Apoptosis : an international journal on programmed cell death20(4)455-65(2015 Apr)

Increased expression of 5-HT(2A) and 5-HT(2B) receptors in detrusor muscle after partial bladder outlet obstruction in rats.
Michishita M, Yano K, Kasahara K, Tomita K, Matsuzaki O
Biomedical research (Tokyo, Japan)36(3)187-94(2015)

Antinociceptive effect of peripheral serotonin 5-HT2B receptor activation on neuropathic pain.
Urtikova N, Berson N, Van Steenwinckel J, Doly S, Truchetto J, Maroteaux L, Pohl M, Conrath M
Pain153(6)1320-31(2012 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

5-HT stimulates DNA synthesis and proliferation in primary cultures of adult rat hepatocytes by acting via autocrine secretion of TGF-alpha induced by the serotonin 5-HT2B receptor/Gq/PLC/Ca2+ pathway.
Title: Serotonin 5-HT2B Receptor-Stimulated DNA Synthesis and Proliferation Are Mediated by Autocrine Secretion of Transforming Growth Factor-? in Primary Cultures of Adult Rat Hepatocytes.

Inhibition of apoptosis via modulation of MAPKs/HSPs is essential for 5-HT2BR blockade mediated cardioprotective effect.
Title: 5-HT2B receptor blockade attenuates ?-adrenergic receptor-stimulated myocardial remodeling in rats via inhibiting apoptosis: role of MAPKs and HSPs.

pBOO induced up-regulation of the 5-HT(2A) and 5-HT(2B) receptors in the detrusor muscle and subserosal layers of the bladder, and such up-regulation may be related to the enhanced bladder contractile response to 5-HT.
Title: Increased expression of 5-HT(2A) and 5-HT(2B) receptors in detrusor muscle after partial bladder outlet obstruction in rats.

5-HT(2B) receptors play a pronociceptive role in peripheral as well as spinal sites in the rat formalin test.
Title: Role of peripheral and spinal 5-HT2B receptors in formalin-induced nociception.

A relationship exists between serotonin, immunocytes, and neuropathic pain during which a critical role of 5-HT(2B) receptors develops in blood-derived macrophages.
Title: Antinociceptive effect of peripheral serotonin 5-HT2B receptor activation on neuropathic pain.

The following Htr2b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Htr2b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa03398	NM_017250.1 Latest version!	Rattus norvegicus 5-hydroxytryptamine receptor 2B (Htr2b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
ORa32456	XM_017596306.1 Latest version!	Rattus norvegicus 5-hydroxytryptamine receptor 2B (Htr2b), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Htr2b ( NM_017250.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_058946.1 Rattus norvegicus 5-hydroxytryptamine receptor 2B (Htr2b), mRNA.

Price & Availability↑

CloneID	ORa03398
Clone ID Related Accession (Same CDS sequence)	NM_017250.1
Accession Version	NM_017250.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1440bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Rattus norvegicus(Norway rat)
Product	5-hydroxytryptamine receptor 2B
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from X66842.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X66842.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689599, SAMEA2689602 [ECO:0000348] ##Evidence-Data-END##

ATGGCTTCAT CTTATAAAAT GTCTGAACAA AGCACAATTT CTGAGCACAT TTTGCAGAAA 
ACATGTGATC ACCTGATCTT GACTGACCGT TCTGGATTAA AGGCAGAATC AGCAGCAGAG 
GAAATGAAGC AGACTGCCGA GAACCAGGGG AATACAGTGC ACTGGGCAGC TCTCCTGATC 
TTCGCGGTAA TAATCCCCAC CATTGGCGGG AACATCCTGG TTATTCTGGC TGTTTCACTG 
GAGAAAAGGC TGCAGTACGC TACCAACTAC TTTCTAATGT CCTTGGCGGT GGCTGATTTG 
CTGGTTGGAT TGTTTGTGAT GCCGATTGCT CTCTTAACAA TCATGTTTGA GGCTACATGG 
CCCCTCCCAC TGGCCCTGTG TCCTGCCTGG TTATTCCTTG ATGTTCTCTT TTCAACTGCC 
TCCATCATGC ATCTCTGTGC CATTTCCCTG GATCGCTATA TAGCCATCAA AAAGCCAATT 
CAGGCCAATC AGTGCAATTC CCGGACTACT GCATTCGTCA AGATTACGGT GGTATGGTTA 
ATTTCAATAG GCATCGCCAT CCCAGTCCCT ATTAAAGGAA TAGAGGCTGA TGTGGTCAAC 
GCACACAACA TCACCTGTGA GCTGACAAAG GACCGCTTTG GCAGTTTCAT GCTCTTTGGG 
TCACTGGCTG CTTTCTTTGC ACCTCTCACC ATCATGATAG TCACCTACTT TCTCACCATT 
CACGCTTTGC GGAAGAAAGC TTACTTGGTC AGAAACAGGC CACCTCAACG CCTAACACGG 
TGGACTGTGT CCACAGTTCT CCAAAGGGAA GACTCATCCT TTTCATCACC AGAAAAGATG 
GTGATGCTGG ATGGCTCTCA CAAGGATAAA ATTCTACCTA ACTCAACTGA TGAGACACTG 
ATGAGAAGAA TGTCCTCAGC AGGAAAAAAA CCAGCCCAGA CCATTTCTAA TGAACAGAGA 
GCCTCAAAGG TCCTTGGAAT TGTGTTTCTC TTCTTTCTGC TTATGTGGTG CCCCTTTTTC 
ATTACAAACG TAACTTTAGC TCTGTGTGAT TCCTGCAACC AGACTACTCT CAAAACACTC 
CTGCAGATAT TTGTGTGGGT AGGCTACGTT TCCTCGGGAG TGAATCCTTT GATCTATACC 
CTCTTCAATA AGACATTTCG GGAAGCATTT GGCAGGTACA TCACCTGCAA TTACCAGGCC 
ACAAAGTCAG TAAAAGTGCT TAGAAAGTGT TCTAGTACAC TCTATTTTGG GAATTCAATG 
GTAGAAAACT CTAAATTTTT CACAAAACAT GGAATTCGAA ATGGGATCAA CCCTGCCATG 
TACCAGAGCC CAGTAAGGCT CCGAAGTTCA ACCATTCAGT CTTCATCCAT CATTCTCCTC 
AATACATTTC TCACTGAAAA CGATGGTGAC AAAGTAGAAG ACCAAGTCAG CTACATATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_058946.1
CDS	227..1666
Translation	MASSYKMSEQSTISEHILQKTCDHLILTDRSGLKAESAAEEMKQTAENQGNTVHWAALLIFAVIIPTIGGNILVILAVSLEKRLQYATNYFLMSLAVADLLVGLFVMPIALLTIMFEATWPLPLALCPAWLFLDVLFSTASIMHLCAISLDRYIAIKKPIQANQCNSRTTAFVKITVVWLISIGIAIPVPIKGIEADVVNAHNITCELTKDRFGSFMLFGSLAAFFAPLTIMIVTYFLTIHALRKKAYLVRNRPPQRLTRWTVSTVLQREDSSFSSPEKMVMLDGSHKDKILPNSTDETLMRRMSSAGKKPAQTISNEQRASKVLGIVFLFFLLMWCPFFITNVTLALCDSCNQTTLKTLLQIFVWVGYVSSGVNPLIYTLFNKTFREAFGRYITCNYQATKSVKVLRKCSSTLYFGNSMVENSKFFTKHGIRNGINPAMYQSPVRLRSSTIQSSSIILLNTFLTENDGDKVEDQVSYI

Target ORF information:

RefSeq Version	NM_017250.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus 5-hydroxytryptamine receptor 2B (Htr2b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_017250.1

ORF Insert Sequence:

ATGGCTTCAT CTTATAAAAT GTCTGAACAA AGCACAATTT CTGAGCACAT TTTGCAGAAA 
ACATGTGATC ACCTGATCTT GACTGACCGT TCTGGATTAA AGGCAGAATC AGCAGCAGAG 
GAAATGAAGC AGACTGCCGA GAACCAGGGG AATACAGTGC ACTGGGCAGC TCTCCTGATC 
TTCGCGGTAA TAATCCCCAC CATTGGCGGG AACATCCTGG TTATTCTGGC TGTTTCACTG 
GAGAAAAGGC TGCAGTACGC TACCAACTAC TTTCTAATGT CCTTGGCGGT GGCTGATTTG 
CTGGTTGGAT TGTTTGTGAT GCCGATTGCT CTCTTAACAA TCATGTTTGA GGCTACATGG 
CCCCTCCCAC TGGCCCTGTG TCCTGCCTGG TTATTCCTTG ATGTTCTCTT TTCAACTGCC 
TCCATCATGC ATCTCTGTGC CATTTCCCTG GATCGCTATA TAGCCATCAA AAAGCCAATT 
CAGGCCAATC AGTGCAATTC CCGGACTACT GCATTCGTCA AGATTACGGT GGTATGGTTA 
ATTTCAATAG GCATCGCCAT CCCAGTCCCT ATTAAAGGAA TAGAGGCTGA TGTGGTCAAC 
GCACACAACA TCACCTGTGA GCTGACAAAG GACCGCTTTG GCAGTTTCAT GCTCTTTGGG 
TCACTGGCTG CTTTCTTTGC ACCTCTCACC ATCATGATAG TCACCTACTT TCTCACCATT 
CACGCTTTGC GGAAGAAAGC TTACTTGGTC AGAAACAGGC CACCTCAACG CCTAACACGG 
TGGACTGTGT CCACAGTTCT CCAAAGGGAA GACTCATCCT TTTCATCACC AGAAAAGATG 
GTGATGCTGG ATGGCTCTCA CAAGGATAAA ATTCTACCTA ACTCAACTGA TGAGACACTG 
ATGAGAAGAA TGTCCTCAGC AGGAAAAAAA CCAGCCCAGA CCATTTCTAA TGAACAGAGA 
GCCTCAAAGG TCCTTGGAAT TGTGTTTCTC TTCTTTCTGC TTATGTGGTG CCCCTTTTTC 
ATTACAAACG TAACTTTAGC TCTGTGTGAT TCCTGCAACC AGACTACTCT CAAAACACTC 
CTGCAGATAT TTGTGTGGGT AGGCTACGTT TCCTCGGGAG TGAATCCTTT GATCTATACC 
CTCTTCAATA AGACATTTCG GGAAGCATTT GGCAGGTACA TCACCTGCAA TTACCAGGCC 
ACAAAGTCAG TAAAAGTGCT TAGAAAGTGT TCTAGTACAC TCTATTTTGG GAATTCAATG 
GTAGAAAACT CTAAATTTTT CACAAAACAT GGAATTCGAA ATGGGATCAA CCCTGCCATG 
TACCAGAGCC CAGTAAGGCT CCGAAGTTCA ACCATTCAGT CTTCATCCAT CATTCTCCTC 
AATACATTTC TCACTGAAAA CGATGGTGAC AAAGTAGAAG ACCAAGTCAG CTACATATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Htr2b ( XM_017596306.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017451795.1 Rattus norvegicus 5-hydroxytryptamine receptor 2B (Htr2b), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa32456
Clone ID Related Accession (Same CDS sequence)	XM_017596306.1
Accession Version	XM_017596306.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1440bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	5-hydroxytryptamine receptor 2B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005108.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTTCAT CTTATAAAAT GTCTGAACAA AGCACAATTT CTGAGCACAT TTTGCAGAAA 
ACATGTGATC ACCTGATCTT GACTGACCGT TCTGGATTAA AGGCAGAATC AGCAGCAGAG 
GAAATGAAGC AGACTGCCGA GAACCAGGGG AATACAGTGC ACTGGGCAGC TCTCCTGATC 
TTCGCGGTAA TAATCCCCAC CATTGGCGGG AACATCCTGG TTATTCTGGC TGTTTCACTG 
GAGAAAAGGC TGCAGTACGC TACCAACTAC TTTCTAATGT CCTTGGCGGT GGCTGATTTG 
CTGGTTGGAT TGTTTGTGAT GCCGATTGCT CTCTTAACAA TCATGTTTGA GGCTACATGG 
CCCCTCCCAC TGGCCCTGTG TCCTGCCTGG TTATTCCTTG ATGTTCTCTT TTCAACTGCC 
TCCATCATGC ATCTCTGTGC CATTTCCCTG GATCGCTATA TAGCCATCAA AAAGCCAATT 
CAGGCCAATC AGTGCAATTC CCGGACTACT GCATTCGTCA AGATTACGGT GGTATGGTTA 
ATTTCAATAG GCATCGCCAT CCCAGTCCCT ATTAAAGGAA TAGAGGCTGA TGTGGTCAAC 
GCACACAACA TCACCTGTGA GCTGACAAAG GACCGCTTTG GCAGTTTCAT GCTCTTTGGG 
TCACTGGCTG CTTTCTTTGC ACCTCTCACC ATCATGATAG TCACCTACTT TCTCACCATT 
CACGCTTTGC GGAAGAAAGC TTACTTGGTC AGAAACAGGC CACCTCAACG CCTAACACGG 
TGGACTGTGT CCACAGTTCT CCAAAGGGAA GACTCATCCT TTTCATCACC AGAAAAGATG 
GCGATGCTGG ATGGCTCTCA CAAGGATAAA ATTCTACCTA ACTCAATTGA TGAGACACTG 
ATGAGAAGAA TGTCCTCAGC AGGAAAAAAA CCAGCCCAGA CCATTTCTAA TGAACAGAGA 
GCCTCAAAGG TCCTTGGAAT TGTGTTTCTC TTCTTTCTGC TTATGTGGTG CCCCTTTTTC 
ATTACAAACG TAACTTTAGC TCTGTGTGAT TCCTGCAACC AGACTACTCT CAAAACACTC 
CTGCAGATAT TTGTGTGGGT AGGCTACGTT TCCTCGGGAG TGAATCCTTT GATCTATACC 
CTCTTCAATA AGACATTTCG GGAAGCATTT GGCAGGTACA TCACCTGCAA TTACCAGGCC 
ACAAAGTCAG TAAAAGTGCT TAGAAAGTGT TCTAGTACAC TCTATTTTGG GAATTCAATG 
GTAGAAAACT CTAAATTTTT CACAAAACAT GGAATTCGAA ATGGGATCAA CCCTGCCATG 
TACCAGAGCC CAGTAAGGCT CCGAAGTTCA ACCATTCAGT CTTCATCCAT CATTCTCCTC 
AATACATTTC TCACTGAAAA CGATGGTGAC AAAGTAGAAG ACCAAGTCAG CTACATATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017451795.1
CDS	4480..5919
Translation	MASSYKMSEQSTISEHILQKTCDHLILTDRSGLKAESAAEEMKQTAENQGNTVHWAALLIFAVIIPTIGGNILVILAVSLEKRLQYATNYFLMSLAVADLLVGLFVMPIALLTIMFEATWPLPLALCPAWLFLDVLFSTASIMHLCAISLDRYIAIKKPIQANQCNSRTTAFVKITVVWLISIGIAIPVPIKGIEADVVNAHNITCELTKDRFGSFMLFGSLAAFFAPLTIMIVTYFLTIHALRKKAYLVRNRPPQRLTRWTVSTVLQREDSSFSSPEKMAMLDGSHKDKILPNSIDETLMRRMSSAGKKPAQTISNEQRASKVLGIVFLFFLLMWCPFFITNVTLALCDSCNQTTLKTLLQIFVWVGYVSSGVNPLIYTLFNKTFREAFGRYITCNYQATKSVKVLRKCSSTLYFGNSMVENSKFFTKHGIRNGINPAMYQSPVRLRSSTIQSSSIILLNTFLTENDGDKVEDQVSYI

Target ORF information:

RefSeq Version	XM_017596306.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus 5-hydroxytryptamine receptor 2B (Htr2b), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017596306.1

ORF Insert Sequence:

ATGGCTTCAT CTTATAAAAT GTCTGAACAA AGCACAATTT CTGAGCACAT TTTGCAGAAA 
ACATGTGATC ACCTGATCTT GACTGACCGT TCTGGATTAA AGGCAGAATC AGCAGCAGAG 
GAAATGAAGC AGACTGCCGA GAACCAGGGG AATACAGTGC ACTGGGCAGC TCTCCTGATC 
TTCGCGGTAA TAATCCCCAC CATTGGCGGG AACATCCTGG TTATTCTGGC TGTTTCACTG 
GAGAAAAGGC TGCAGTACGC TACCAACTAC TTTCTAATGT CCTTGGCGGT GGCTGATTTG 
CTGGTTGGAT TGTTTGTGAT GCCGATTGCT CTCTTAACAA TCATGTTTGA GGCTACATGG 
CCCCTCCCAC TGGCCCTGTG TCCTGCCTGG TTATTCCTTG ATGTTCTCTT TTCAACTGCC 
TCCATCATGC ATCTCTGTGC CATTTCCCTG GATCGCTATA TAGCCATCAA AAAGCCAATT 
CAGGCCAATC AGTGCAATTC CCGGACTACT GCATTCGTCA AGATTACGGT GGTATGGTTA 
ATTTCAATAG GCATCGCCAT CCCAGTCCCT ATTAAAGGAA TAGAGGCTGA TGTGGTCAAC 
GCACACAACA TCACCTGTGA GCTGACAAAG GACCGCTTTG GCAGTTTCAT GCTCTTTGGG 
TCACTGGCTG CTTTCTTTGC ACCTCTCACC ATCATGATAG TCACCTACTT TCTCACCATT 
CACGCTTTGC GGAAGAAAGC TTACTTGGTC AGAAACAGGC CACCTCAACG CCTAACACGG 
TGGACTGTGT CCACAGTTCT CCAAAGGGAA GACTCATCCT TTTCATCACC AGAAAAGATG 
GCGATGCTGG ATGGCTCTCA CAAGGATAAA ATTCTACCTA ACTCAATTGA TGAGACACTG 
ATGAGAAGAA TGTCCTCAGC AGGAAAAAAA CCAGCCCAGA CCATTTCTAA TGAACAGAGA 
GCCTCAAAGG TCCTTGGAAT TGTGTTTCTC TTCTTTCTGC TTATGTGGTG CCCCTTTTTC 
ATTACAAACG TAACTTTAGC TCTGTGTGAT TCCTGCAACC AGACTACTCT CAAAACACTC 
CTGCAGATAT TTGTGTGGGT AGGCTACGTT TCCTCGGGAG TGAATCCTTT GATCTATACC 
CTCTTCAATA AGACATTTCG GGAAGCATTT GGCAGGTACA TCACCTGCAA TTACCAGGCC 
ACAAAGTCAG TAAAAGTGCT TAGAAAGTGT TCTAGTACAC TCTATTTTGG GAATTCAATG 
GTAGAAAACT CTAAATTTTT CACAAAACAT GGAATTCGAA ATGGGATCAA CCCTGCCATG 
TACCAGAGCC CAGTAAGGCT CCGAAGTTCA ACCATTCAGT CTTCATCCAT CATTCTCCTC 
AATACATTTC TCACTGAAAA CGATGGTGAC AAAGTAGAAG ACCAAGTCAG CTACATATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Serotonin 5-HT2B Receptor-Stimulated DNA Synthesis and Proliferation Are Mediated by Autocrine Secretion of Transforming Growth Factor-? in Primary Cultures of Adult Rat Hepatocytes.
Biological & pharmaceutical bulletin39(4)570-7(2016)
Naito K,Moteki H,Kimura M,Natsume H,Ogihara M

5-HT2B receptor blockade attenuates ?-adrenergic receptor-stimulated myocardial remodeling in rats via inhibiting apoptosis: role of MAPKs and HSPs.
Apoptosis : an international journal on programmed cell death20(4)455-65(2015 Apr)
Bharti S,Rani N,Bhatia J,Arya DS

Increased expression of 5-HT(2A) and 5-HT(2B) receptors in detrusor muscle after partial bladder outlet obstruction in rats.
Biomedical research (Tokyo, Japan)36(3)187-94(2015)
Michishita M,Yano K,Kasahara K,Tomita K,Matsuzaki O

Antinociceptive effect of peripheral serotonin 5-HT2B receptor activation on neuropathic pain.
Pain153(6)1320-31(2012 Jun)
Urtikova N,Berson N,Van Steenwinckel J,Doly S,Truchetto J,Maroteaux L,Pohl M,Conrath M

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Htr2b cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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