Gprc6a cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Gprc6a
Entrez Gene ID	294394
Full Name	G protein-coupled receptor, class C, group 6, member A
General protein information	Preferred Names G protein-coupled receptor, class C, group 6, member A Names G-protein coupled receptor family C group 6 member A
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 20 Map Location: 20q11

mRNA and Protein(s)

mRNA	Protein	Name
NM_001271106.1	NP_001258035.1	G-protein coupled receptor family C group 6 member A precursor

Pathways from BioSystems

Homologies

	GPRC6A	XP_001111107.1
Homo sapiens (human)	GPRC6A	NP_683766.2
Danio rerio (zebrafish)	gprc6a	NP_001008731.1
Mus musculus (house mouse)	Gprc6a	NP_694711.1
Gallus gallus (chicken)	GPRC6A	XP_426177.3
Pan troglodytes (chimpanzee)	GPRC6A	XP_527484.2
Rattus norvegicus (Norway rat)	Gprc6a	NP_001258035.1
Canis lupus familiaris (dog)	GPRC6A	XP_541212.1
Bos taurus (cattle)	GPRC6A	XP_005210818.1
Xenopus tropicalis (tropical clawed frog)	LOC100487890	XP_002938346.1

Gene Ontology
Bibliography

Related articles in PubMed

The GPRC6A receptor displays constitutive internalization and sorting to the slow recycling pathway.
Jacobsen SE, Ammendrup-Johnsen I, Jansen AM, Gether U, Madsen KL, Br?uner-Osborne H
The Journal of biological chemistry292(17)6910-6926(2017 04)

The rat GPRC6A: cloning and characterization.
Wellendorph P, Burhenne N, Christiansen B, Walter B, Schmale H, Br?uner-Osborne H
Gene396(2)257-67(2007 Jul)

Identification of a novel extracellular cation-sensing G-protein-coupled receptor.
Pi M, Faber P, Ekema G, Jackson PD, Ting A, Wang N, Fontilla-Poole M, Mays RW, Brunden KR, Harrington JJ, Quarles LD
The Journal of biological chemistry280(48)40201-9(2005 Dec)

Molecular cloning, expression, and sequence analysis of GPRC6A, a novel family C G-protein-coupled receptor.
Wellendorph P, Br?uner-Osborne H
Gene33537-46(2004 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

GPRC6A predominantly undergoes constitutive internalization with the early endosome marker Rab5 and the long loop recycling endosome marker Rab11 and to a much lesser extent with the late endosome marker Rab7
Title: The GPRC6A receptor displays constitutive internalization and sorting to the slow recycling pathway.

cloning and characterization of rat GPRC6A
Title: The rat GPRC6A: cloning and characterization.

The following Gprc6a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Gprc6a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa13764	NM_001271106.1 Latest version!	Rattus norvegicus G protein-coupled receptor, class C, group 6, member A (Gprc6a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Gprc6a ( NM_001271106.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001258035.1 Rattus norvegicus G protein-coupled receptor, class C, group 6, member A (Gprc6a), mRNA.

Price & Availability↑

CloneID	ORa13764
Clone ID Related Accession (Same CDS sequence)	NM_001271106.1
Accession Version	NM_001271106.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2787bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Rattus norvegicus(Norway rat)
Product	G-protein coupled receptor family C group 6 member A precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07045041.1. On Aug 31, 2012 this sequence version replaced XM_228164.6. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AJ535460.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00632253, SAMN02642672 [ECO:0000350] ##Evidence-Data-END##

ATGGCCCTAT CATTTGTATT TATTACTTGC TTCATGATTC TTCTTGATAC CTCCCAGTCT 
TGTCATACCC CAGATGACTT CGTGGCTATC ACTTCTCCTG GACATATCAT GATTGGTGGT 
TTGTTTGCCA TTCACGAAAA AATGTTGTCC TCAGATGACC ATCCCAGGCA ACCACAAATC 
CAGAAGTGTG TTGGTTTTGA AATATCAGTG TTTCTTCAAA CTCTGGCTAT GATACACAGC 
ATTGAGATGA TCAATAACTC AAGCCTGTTG TCCGGAGTTA AGCTGGGGTA TGAAATCTAT 
GACACTTGTA CTGAAGTCAC AGCGGCAATG GCTGCCACCC TGAGGTTCCT CTCTAAATTC 
AACTGCTCTA GAGAAACCGT GATCTTTCAA TGTGACTATT CCAGCTACGT GCCAAGGGTC 
AAGGCCATCA TAGGTGCTGG CTACTCTGAA ATATCCATGG CGGTCTCGAG GATGCTGAAT 
TTACAGCTCA TGCCACAGGT GAGTTATGAA TCCACTGCAG AAATCCTGAG TGACAAAATC 
CGCTTTCCTT CGTTTTTACG AACCGTGCCC AGTGACTTCT ACCAAACTAA AGCAATGGCC 
CACCTGATCC GACAATCCGG ATGGAACTGG GTTGGTGCCA TAACAACCGA CGATGATTAT 
GGAAGACTAG CGCTCAACAC ATTTGCAATC CAGGCTGCTG AAAACAATGT GTGCATCGCC 
TTCAAAGAGG TTCTGCCAGC CTTCCTCTCA GATAATACCA TTGAAGTGAG AATCAACCAG 
ACTCTGGAGA AAATCATTGC CGAAGCCCAG GTCAATGTCA TCGTGGTGTT TCTTAGGAAA 
TTCCACGTCT TCAATCTCTT CAACAAAGCC ATCGAGAGGA AAATAAGTAA GATCTGGATT 
GCTAGTGATA ACTGGTCAAC TGCTGCCAAG ATTATCACCA TTCCCAATGT TAAGAAGCTT 
GGCAAAGTAG TGGGCTTTAC TTTTAGGAGA GGAAATATGT CTTCTTTCCA TTCTTTTCTT 
CAAACTCTGC ATATGTACCC CAGTGACAAT AACAAACCCC TACATGAGTT TGCCATGCTT 
TTTTCTGCCT GTAAACACAT CAAAGATGGT GATTTGAGCC AATGCATTTC CAACTATTCT 
CAGGCAACTT GGACCTATGA CACTACCAAG ACCATTGAGA CCCATTTATT CAAGAGAAAT 
GACTTCCTTT GGCATTATAC TGAGCCAGGA CTCATTCACA GCATTCAGCT TGCTGTGCTT 
GCCTTGGGCC ATGCCATCCG GGATCTGTGC CAAGATCGAG ACTGCCAGAA ACCCAACGCC 
TTTCAGCCAT GGGAGCTACT TGCGGTGCTG AAAAACGTGA CATTCACTGA CGGAAAAAAC 
TCATTTCATT TTGATGCCCA TGGGGATTTA AATACTGGTT ACGAGGTGGT GCTCTGGAAA 
GAGACTAACG GCCTCATGAC TGTCACGAAG ATGGCAGAAT ATGACCTGCA GCATGACGTC 
TTCATCACCA CAAACCAAGA AACAAAGCAT GAATTCAGGA AACTTAAGCA AATTCTATCT 
AAATGCTCCA AAGAATGCAT TCCTGGTCAA ATGAAGAAAG CCACAGGAAG CCAACACAGC 
TGTTGCTATG AATGTGTGAA CTGCCCAGAA AACCACTACA GTAATGAGAC AGACATGGAT 
CACTGCCTCG TATGCAACAA CGAAACCCAC TGGGCCCCAG TAAGGAGCAC GATGTGCTTC 
GAGAAGGAAG TGGAGTATCT TGACTGGGAT GACTCCTTGG CTCTCCTCCT CATTGCCCTC 
TCCCTACTTG GAATTGCCTT TGTTCTGGCC GTTGGCATAA TATTTACAAG AAACCTGAAG 
ACACCTGTGG TGAAATCATC TGGGGGATTA GTGGTCTGTT ACGTGATGCT CGCCTGCCAT 
GCCCTCAACT TTGCCAGCAC AGGCTTTTTT ATTGGAGAAC CACAGGACTT CACGTGCAAG 
ACCAGGCAGA CCCTGTTTGG CGTGAGCTTT ACTCTGTGTG TCTCCTGTAT TTTGACGAAG 
TCCCTGAAAA TTTTGCTAGC CTTCAGCTTC GACCCCACGC TGAAGACATT CCTGAAGTGT 
CTCTATAGGC CAGTCCCCAT TGTCCTTACC TGCACGGGCA TTCAAGTGGT CATTTGCACG 
CTTTGGCTGG TCCTGGCAGC ACCTACTGTG GAAGAGAACA CCTCCTTGCC TAGAGTCATT 
ATCCTAGAAT GTGAGGAGGG ATCTGCACTG GCGTTTGGCA CCATGCTGGG CTACATTGCA 
GTTCTGGCCT TCATTTGTTT TGTATTTGCA TTCAAGGGGA GGAAGCTTCC TGAGAATTAC 
AACGAAGCTA AGTTCCTGAC CTTTGGGATG CTGATTTACT TCATAGCTTG GATCACATTC 
ATCCCAGTCT ATGCTACCAC TTTCGGCAAG TATTTGCCCG CTGTGGAGAT CATAGTCATT 
CTGATATCCA ACTATGGTAT CCTCTGCTGT ACATTCTTCC CCAAGTGCTA CATTATTCTT 
TGCAAGCAAA AGACTAACAC TAAGTCAGTC TTCCTCCAGA TGGTTTACAA TTACTCTGCT 
CACAGCGTGG ACAGCCTTGC CTTGAGTCAC GTATCCCTGG ACTCCGCCAG CCACAGTACT 
GCAACAACCA ACCCGAGGCC TGGTAACAAG ACTGCAGCCT GTCAGAATTA CAAACATCTT 
CCTGTACAAG TGCTTGCTCA CACAGGCATG GAAAAGACTA TGCACGCGTC TAAAACTTTG 
CATCAGAAAA GAAGTTCAAG TATATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001258035.1
CDS	25..2811
Translation	MALSFVFITCFMILLDTSQSCHTPDDFVAITSPGHIMIGGLFAIHEKMLSSDDHPRQPQIQKCVGFEISVFLQTLAMIHSIEMINNSSLLSGVKLGYEIYDTCTEVTAAMAATLRFLSKFNCSRETVIFQCDYSSYVPRVKAIIGAGYSEISMAVSRMLNLQLMPQVSYESTAEILSDKIRFPSFLRTVPSDFYQTKAMAHLIRQSGWNWVGAITTDDDYGRLALNTFAIQAAENNVCIAFKEVLPAFLSDNTIEVRINQTLEKIIAEAQVNVIVVFLRKFHVFNLFNKAIERKISKIWIASDNWSTAAKIITIPNVKKLGKVVGFTFRRGNMSSFHSFLQTLHMYPSDNNKPLHEFAMLFSACKHIKDGDLSQCISNYSQATWTYDTTKTIETHLFKRNDFLWHYTEPGLIHSIQLAVLALGHAIRDLCQDRDCQKPNAFQPWELLAVLKNVTFTDGKNSFHFDAHGDLNTGYEVVLWKETNGLMTVTKMAEYDLQHDVFITTNQETKHEFRKLKQILSKCSKECIPGQMKKATGSQHSCCYECVNCPENHYSNETDMDHCLVCNNETHWAPVRSTMCFEKEVEYLDWDDSLALLLIALSLLGIAFVLAVGIIFTRNLKTPVVKSSGGLVVCYVMLACHALNFASTGFFIGEPQDFTCKTRQTLFGVSFTLCVSCILTKSLKILLAFSFDPTLKTFLKCLYRPVPIVLTCTGIQVVICTLWLVLAAPTVEENTSLPRVIILECEEGSALAFGTMLGYIAVLAFICFVFAFKGRKLPENYNEAKFLTFGMLIYFIAWITFIPVYATTFGKYLPAVEIIVILISNYGILCCTFFPKCYIILCKQKTNTKSVFLQMVYNYSAHSVDSLALSHVSLDSASHSTATTNPRPGNKTAACQNYKHLPVQVLAHTGMEKTMHASKTLHQKRSSSI

Target ORF information:

RefSeq Version	NM_001271106.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus G protein-coupled receptor, class C, group 6, member A (Gprc6a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001271106.1

ORF Insert Sequence:

ATGGCCCTAT CATTTGTATT TATTACTTGC TTCATGATTC TTCTTGATAC CTCCCAGTCT 
TGTCATACCC CAGATGACTT CGTGGCTATC ACTTCTCCTG GACATATCAT GATTGGTGGT 
TTGTTTGCCA TTCACGAAAA AATGTTGTCC TCAGATGACC ATCCCAGGCA ACCACAAATC 
CAGAAGTGTG TTGGTTTTGA AATATCAGTG TTTCTTCAAA CTCTGGCTAT GATACACAGC 
ATTGAGATGA TCAATAACTC AAGCCTGTTG TCCGGAGTTA AGCTGGGGTA TGAAATCTAT 
GACACTTGTA CTGAAGTCAC AGCGGCAATG GCTGCCACCC TGAGGTTCCT CTCTAAATTC 
AACTGCTCTA GAGAAACCGT GATCTTTCAA TGTGACTATT CCAGCTACGT GCCAAGGGTC 
AAGGCCATCA TAGGTGCTGG CTACTCTGAA ATATCCATGG CGGTCTCGAG GATGCTGAAT 
TTACAGCTCA TGCCACAGGT GAGTTATGAA TCCACTGCAG AAATCCTGAG TGACAAAATC 
CGCTTTCCTT CGTTTTTACG AACCGTGCCC AGTGACTTCT ACCAAACTAA AGCAATGGCC 
CACCTGATCC GACAATCCGG ATGGAACTGG GTTGGTGCCA TAACAACCGA CGATGATTAT 
GGAAGACTAG CGCTCAACAC ATTTGCAATC CAGGCTGCTG AAAACAATGT GTGCATCGCC 
TTCAAAGAGG TTCTGCCAGC CTTCCTCTCA GATAATACCA TTGAAGTGAG AATCAACCAG 
ACTCTGGAGA AAATCATTGC CGAAGCCCAG GTCAATGTCA TCGTGGTGTT TCTTAGGAAA 
TTCCACGTCT TCAATCTCTT CAACAAAGCC ATCGAGAGGA AAATAAGTAA GATCTGGATT 
GCTAGTGATA ACTGGTCAAC TGCTGCCAAG ATTATCACCA TTCCCAATGT TAAGAAGCTT 
GGCAAAGTAG TGGGCTTTAC TTTTAGGAGA GGAAATATGT CTTCTTTCCA TTCTTTTCTT 
CAAACTCTGC ATATGTACCC CAGTGACAAT AACAAACCCC TACATGAGTT TGCCATGCTT 
TTTTCTGCCT GTAAACACAT CAAAGATGGT GATTTGAGCC AATGCATTTC CAACTATTCT 
CAGGCAACTT GGACCTATGA CACTACCAAG ACCATTGAGA CCCATTTATT CAAGAGAAAT 
GACTTCCTTT GGCATTATAC TGAGCCAGGA CTCATTCACA GCATTCAGCT TGCTGTGCTT 
GCCTTGGGCC ATGCCATCCG GGATCTGTGC CAAGATCGAG ACTGCCAGAA ACCCAACGCC 
TTTCAGCCAT GGGAGCTACT TGCGGTGCTG AAAAACGTGA CATTCACTGA CGGAAAAAAC 
TCATTTCATT TTGATGCCCA TGGGGATTTA AATACTGGTT ACGAGGTGGT GCTCTGGAAA 
GAGACTAACG GCCTCATGAC TGTCACGAAG ATGGCAGAAT ATGACCTGCA GCATGACGTC 
TTCATCACCA CAAACCAAGA AACAAAGCAT GAATTCAGGA AACTTAAGCA AATTCTATCT 
AAATGCTCCA AAGAATGCAT TCCTGGTCAA ATGAAGAAAG CCACAGGAAG CCAACACAGC 
TGTTGCTATG AATGTGTGAA CTGCCCAGAA AACCACTACA GTAATGAGAC AGACATGGAT 
CACTGCCTCG TATGCAACAA CGAAACCCAC TGGGCCCCAG TAAGGAGCAC GATGTGCTTC 
GAGAAGGAAG TGGAGTATCT TGACTGGGAT GACTCCTTGG CTCTCCTCCT CATTGCCCTC 
TCCCTACTTG GAATTGCCTT TGTTCTGGCC GTTGGCATAA TATTTACAAG AAACCTGAAG 
ACACCTGTGG TGAAATCATC TGGGGGATTA GTGGTCTGTT ACGTGATGCT CGCCTGCCAT 
GCCCTCAACT TTGCCAGCAC AGGCTTTTTT ATTGGAGAAC CACAGGACTT CACGTGCAAG 
ACCAGGCAGA CCCTGTTTGG CGTGAGCTTT ACTCTGTGTG TCTCCTGTAT TTTGACGAAG 
TCCCTGAAAA TTTTGCTAGC CTTCAGCTTC GACCCCACGC TGAAGACATT CCTGAAGTGT 
CTCTATAGGC CAGTCCCCAT TGTCCTTACC TGCACGGGCA TTCAAGTGGT CATTTGCACG 
CTTTGGCTGG TCCTGGCAGC ACCTACTGTG GAAGAGAACA CCTCCTTGCC TAGAGTCATT 
ATCCTAGAAT GTGAGGAGGG ATCTGCACTG GCGTTTGGCA CCATGCTGGG CTACATTGCA 
GTTCTGGCCT TCATTTGTTT TGTATTTGCA TTCAAGGGGA GGAAGCTTCC TGAGAATTAC 
AACGAAGCTA AGTTCCTGAC CTTTGGGATG CTGATTTACT TCATAGCTTG GATCACATTC 
ATCCCAGTCT ATGCTACCAC TTTCGGCAAG TATTTGCCCG CTGTGGAGAT CATAGTCATT 
CTGATATCCA ACTATGGTAT CCTCTGCTGT ACATTCTTCC CCAAGTGCTA CATTATTCTT 
TGCAAGCAAA AGACTAACAC TAAGTCAGTC TTCCTCCAGA TGGTTTACAA TTACTCTGCT 
CACAGCGTGG ACAGCCTTGC CTTGAGTCAC GTATCCCTGG ACTCCGCCAG CCACAGTACT 
GCAACAACCA ACCCGAGGCC TGGTAACAAG ACTGCAGCCT GTCAGAATTA CAAACATCTT 
CCTGTACAAG TGCTTGCTCA CACAGGCATG GAAAAGACTA TGCACGCGTC TAAAACTTTG 
CATCAGAAAA GAAGTTCAAG TATATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The GPRC6A receptor displays constitutive internalization and sorting to the slow recycling pathway.
The Journal of biological chemistry292(17)6910-6926(2017 04)
Jacobsen SE,Ammendrup-Johnsen I,Jansen AM,Gether U,Madsen KL,Br?uner-Osborne H

The rat GPRC6A: cloning and characterization.
Gene396(2)257-67(2007 Jul)
Wellendorph P,Burhenne N,Christiansen B,Walter B,Schmale H,Br?uner-Osborne H

Identification of a novel extracellular cation-sensing G-protein-coupled receptor.
The Journal of biological chemistry280(48)40201-9(2005 Dec)
Pi M,Faber P,Ekema G,Jackson PD,Ting A,Wang N,Fontilla-Poole M,Mays RW,Brunden KR,Harrington JJ,Quarles LD

Molecular cloning, expression, and sequence analysis of GPRC6A, a novel family C G-protein-coupled receptor.
Gene33537-46(2004 Jun)
Wellendorph P,Br?uner-Osborne H

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Gprc6a cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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