Pms2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Pms2
Entrez Gene ID	288479
Full Name	PMS1 homolog 2, mismatch repair system component
General protein information	Preferred Names PMS1 homolog 2, mismatch repair system component Names mismatch repair endonuclease PMS2 PMS2 postmeiotic segregation increased 2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 12 Map Location: 12p11

mRNA and Protein(s)

mRNA	Protein	Name
XM_017598288.1	XP_017453777.1	mismatch repair endonuclease PMS2 isoform X2
NM_001105908.1	NP_001099378.1	mismatch repair endonuclease PMS2
XM_006248862.3	XP_006248924.1	mismatch repair endonuclease PMS2 isoform X1

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Pms2	NP_001099378.1
Gallus gallus (chicken)	PMS2	XP_004951163.1

Gene Ontology
Bibliography

Related articles in PubMed

Refining the role of PMS2 in Lynch syndrome: germline mutational analysis improved by comprehensive assessment of variants.
Borr?s E, Pineda M, Cadi?anos J, Del Valle J, Brieger A, Hinrichsen I, Cabanillas R, Navarro M, Brunet J, Sanjuan X, Musulen E, van der Klift H, L?zaro C, Plotz G, Blanco I, Capell? G
Journal of medical genetics50(8)552-63(2013 Aug)

Pms2 suppresses large expansions of the (GAA?TTC)n sequence in neuronal tissues.
Bourn RL, De Biase I, Pinto RM, Sandi C, Al-Mahdawi S, Pook MA, Bidichandani SI
PloS one7(10)e47085(2012)

Genetic susceptibility to distinct bladder cancer subphenotypes.
Guey LT, Garc?a-Closas M, Murta-Nascimento C, Lloreta J, Palencia L, Kogevinas M, Rothman N, Vellalta G, Calle ML, Marenne G, Tard?n A, Carrato A, Garc?a-Closas R, Serra C, Silverman DT, Chanock S, Real FX, Malats N,
European urology57(2)283-92(2010 Feb)

The elevated expression of a mismatch repair protein is a predictor for biochemical recurrence after radical prostatectomy.
Norris AM, Gentry M, Peehl DM, D'Agostino R Jr, Scarpinato KD
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology18(1)57-64(2009 Jan)

Mismatch repair gene polymorphisms and survival in invasive ovarian cancer patients.
Mann A, Hogdall E, Ramus SJ, DiCioccio RA, Hogdall C, Quaye L, McGuire V, Whittemore AS, Shah M, Greenberg D, Easton DF, Ponder BA, Kjaer SK, Gayther SA, Thompson DJ, Pharoah PD, Song H
European journal of cancer (Oxford, England : 1990)44(15)2259-65(2008 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Pms2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pms2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa10707	NM_001105908.1 Latest version!	Rattus norvegicus PMS1 homolog 2, mismatch repair system component (Pms2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$321.30 $459.00
ORa34600	XM_006248862.3 Latest version!	Rattus norvegicus PMS1 homolog 2, mismatch repair system component (Pms2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
ORa57793	XM_017598288.1 Latest version!	Rattus norvegicus PMS1 homolog 2, mismatch repair system component (Pms2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Pms2 ( NM_001105908.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001099378.1 Rattus norvegicus PMS1 homolog 2, mismatch repair system component (Pms2), mRNA.

Price & Availability↑

CloneID	ORa10707
Clone ID Related Accession (Same CDS sequence)	NM_001105908.1
Accession Version	NM_001105908.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1629bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-27
Organism	Rattus norvegicus(Norway rat)
Product	mismatch repair endonuclease PMS2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH474012.1. On or before Oct 3, 2007 this sequence version replaced XM_213712.4, XM_001063043.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGTATAATC GGCACCAGTA TCCATTTGTC GTTCTTAACG TGTCCGTGGA CTCGGAATGT 
GTGGATATTA ACGTGACCCC AGATAAAAGG CAGATTTTAC TACAGGAAGA GAAGCTTTTG 
CTGGCAGTTT TAAAGACGTC CTTGATGGGA ATGTTCGACA GTGATGCAAA CAAGCTTAGT 
GTCAACCAGC AGCCGCTGCT GAATGTCGAA GGTAACTTAG TAAAGCTACA TACCGCAGAA 
GTAGGAGAGC AAGAGAACTC TCCTTCATTG AGGATCACAG CGGAAGAGAA AAGGGTAGCA 
TCTGTGTCTA GGCTGAGAGA GGCCTATTCT CTTCATCGTA CCACAGAGAC CAAGTCTTGG 
GGCCCAGAGA CTCCTGAACT GAAACAGAGT TTTCCAAGTC AGAAAAGGGG TGTATCATCA 
TCTTGTCCTT CAGACATCAT CTCTTATAGA GGCCTGTGTG GCTCACAGGA CAAATTGGTG 
AGTCCCACGG ATAGCCCTGG TGACTGTATG GACAGAGAAA AAGGAGAAAA GGACTCAGGG 
CTTAGCAGCA CCTCAGCTGG CTCTGAGGAA GGGTTCAGCA CCCCAGAAGT GGCCAGTAGC 
TTTAGCAGTG ACTGCAACGT GAGCTCCCCA GAGGACAGAC CTTCTCAGGA AAACACAAAC 
TGTGGCGAGC AGTTCCTTGA AGTGGATGAC CACCTTTCAG GTACAGGACA CCATTTGAAG 
CCAGAAGACA ATGGATATAA ATGTCGAGCT TCACTTCCAC CAACTCGGCT CTCTCCCTCA 
AATGCTAAGC GTTTCAGGAC AGAGGACAGG CCTTCAAATG TTGGCGTTCC TCAGAACACC 
TCAGCAGCTG AGGTTGACGT AGCTGTAAAA ATTAATAAGA AAATAGTGCT CCTTGACTTC 
TCTCTGAGCT CTTTAGCTAA ACAAATGAAG CAGTTACAGC ACCTGAAGCA GCAGAGCAAA 
AGCGAACACA ATTACAGGAA ATTTAGGGCC AAGATTTGCC CTGGAGAAAA TCAAGCAGCA 
GAAGATGAAC TCAGAAGAGA GATTAGGAAG TCGATGTTCG CAGAGATGGA GATCTTGGGT 
CAGTTTAACC TGGGATTCAT CGTAACCAAA CTGAAGGAGG ACCTCTTCCT GGTGGACCAG 
CACGCCGCCG ACGAGAAGTA CAACTTTGAG ATGCTGCAGC AGCACACGGT GCTCCAGGCT 
CAGAGGCTCA TCACTCCCCA GACTCTGAAC TTAACTGCTG TCAATGAAGC TGTGCTGATA 
GAAAATCTGG AAATATTCAG AAAGAATGGC TTTGACTTTA TCATTGATGA AGATGCTCCA 
GTCACTGAAA GGGCTAAACT GATTTCCTTA CCCACTAGTA AAAACTGGAC CTTTGGACCC 
CAAGATATCG ATGAACTGAT CTTTATGCTC AGTGACAGCC CTGGGGTCAT GTGCCGGCCC 
TCGAGAGTCA GACAGATGTT TGCTTCCCGA GCGTGTCGGA AGTCTGTGAT GATTGGAACC 
GCTCTCAGTG CAAGTGAGAT GAAGAAGCTC ATCTCCCACA TGGGTGAGAT GGACCACCCC 
TGGAACTGCC CCCACGGAAG GCCGACCATG AGGCACATTG CAAATCTGGA TGTCATCTCC 
CAGAACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001099378.1
CDS	926..2554
Translation	MYNRHQYPFVVLNVSVDSECVDINVTPDKRQILLQEEKLLLAVLKTSLMGMFDSDANKLSVNQQPLLNVEGNLVKLHTAEVGEQENSPSLRITAEEKRVASVSRLREAYSLHRTTETKSWGPETPELKQSFPSQKRGVSSSCPSDIISYRGLCGSQDKLVSPTDSPGDCMDREKGEKDSGLSSTSAGSEEGFSTPEVASSFSSDCNVSSPEDRPSQENTNCGEQFLEVDDHLSGTGHHLKPEDNGYKCRASLPPTRLSPSNAKRFRTEDRPSNVGVPQNTSAAEVDVAVKINKKIVLLDFSLSSLAKQMKQLQHLKQQSKSEHNYRKFRAKICPGENQAAEDELRREIRKSMFAEMEILGQFNLGFIVTKLKEDLFLVDQHAADEKYNFEMLQQHTVLQAQRLITPQTLNLTAVNEAVLIENLEIFRKNGFDFIIDEDAPVTERAKLISLPTSKNWTFGPQDIDELIFMLSDSPGVMCRPSRVRQMFASRACRKSVMIGTALSASEMKKLISHMGEMDHPWNCPHGRPTMRHIANLDVISQN

Target ORF information:

RefSeq Version	NM_001105908.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus PMS1 homolog 2, mismatch repair system component (Pms2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001105908.1

ORF Insert Sequence:

ATGTATAATC GGCACCAGTA TCCATTTGTC GTTCTTAACG TGTCCGTGGA CTCGGAATGT 
GTGGATATTA ACGTGACCCC AGATAAAAGG CAGATTTTAC TACAGGAAGA GAAGCTTTTG 
CTGGCAGTTT TAAAGACGTC CTTGATGGGA ATGTTCGACA GTGATGCAAA CAAGCTTAGT 
GTCAACCAGC AGCCGCTGCT GAATGTCGAA GGTAACTTAG TAAAGCTACA TACCGCAGAA 
GTAGGAGAGC AAGAGAACTC TCCTTCATTG AGGATCACAG CGGAAGAGAA AAGGGTAGCA 
TCTGTGTCTA GGCTGAGAGA GGCCTATTCT CTTCATCGTA CCACAGAGAC CAAGTCTTGG 
GGCCCAGAGA CTCCTGAACT GAAACAGAGT TTTCCAAGTC AGAAAAGGGG TGTATCATCA 
TCTTGTCCTT CAGACATCAT CTCTTATAGA GGCCTGTGTG GCTCACAGGA CAAATTGGTG 
AGTCCCACGG ATAGCCCTGG TGACTGTATG GACAGAGAAA AAGGAGAAAA GGACTCAGGG 
CTTAGCAGCA CCTCAGCTGG CTCTGAGGAA GGGTTCAGCA CCCCAGAAGT GGCCAGTAGC 
TTTAGCAGTG ACTGCAACGT GAGCTCCCCA GAGGACAGAC CTTCTCAGGA AAACACAAAC 
TGTGGCGAGC AGTTCCTTGA AGTGGATGAC CACCTTTCAG GTACAGGACA CCATTTGAAG 
CCAGAAGACA ATGGATATAA ATGTCGAGCT TCACTTCCAC CAACTCGGCT CTCTCCCTCA 
AATGCTAAGC GTTTCAGGAC AGAGGACAGG CCTTCAAATG TTGGCGTTCC TCAGAACACC 
TCAGCAGCTG AGGTTGACGT AGCTGTAAAA ATTAATAAGA AAATAGTGCT CCTTGACTTC 
TCTCTGAGCT CTTTAGCTAA ACAAATGAAG CAGTTACAGC ACCTGAAGCA GCAGAGCAAA 
AGCGAACACA ATTACAGGAA ATTTAGGGCC AAGATTTGCC CTGGAGAAAA TCAAGCAGCA 
GAAGATGAAC TCAGAAGAGA GATTAGGAAG TCGATGTTCG CAGAGATGGA GATCTTGGGT 
CAGTTTAACC TGGGATTCAT CGTAACCAAA CTGAAGGAGG ACCTCTTCCT GGTGGACCAG 
CACGCCGCCG ACGAGAAGTA CAACTTTGAG ATGCTGCAGC AGCACACGGT GCTCCAGGCT 
CAGAGGCTCA TCACTCCCCA GACTCTGAAC TTAACTGCTG TCAATGAAGC TGTGCTGATA 
GAAAATCTGG AAATATTCAG AAAGAATGGC TTTGACTTTA TCATTGATGA AGATGCTCCA 
GTCACTGAAA GGGCTAAACT GATTTCCTTA CCCACTAGTA AAAACTGGAC CTTTGGACCC 
CAAGATATCG ATGAACTGAT CTTTATGCTC AGTGACAGCC CTGGGGTCAT GTGCCGGCCC 
TCGAGAGTCA GACAGATGTT TGCTTCCCGA GCGTGTCGGA AGTCTGTGAT GATTGGAACC 
GCTCTCAGTG CAAGTGAGAT GAAGAAGCTC ATCTCCCACA TGGGTGAGAT GGACCACCCC 
TGGAACTGCC CCCACGGAAG GCCGACCATG AGGCACATTG CAAATCTGGA TGTCATCTCC 
CAGAACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pms2 ( XM_006248862.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006248924.1 Rattus norvegicus PMS1 homolog 2, mismatch repair system component (Pms2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa34600
Clone ID Related Accession (Same CDS sequence)	XM_006248862.3
Accession Version	XM_006248862.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2562bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	mismatch repair endonuclease PMS2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005111.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006248862.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAACCAA CTGAGGGCGC GAGTACAGAA TGTGCTAAGG CCATCAAGCC TATTGATGGG 
AAGTCAGTCC ATCAGATTTG CTCTGGGCAG GTGGTACTCA GTTTAAGCAC TGCTGTGAAG 
GAGTTGATAG AAAATAGTGT AGATGCCGGT GCTACTAGTA TTGATCTAAG GCTTAAAGAC 
TATGGAGTGG ACCTCATTGA AGTTTCAGAC AATGGATGTG GGGTAGAAGA AGAAAACTTT 
GAAGGTCTAG CTCTGAAACA TCACACCTCT AAGATTCGAG AGTTTGCCGA CCTCACGCAG 
GTTGAAACTT TCGGCTTTCG GGGGGAAGCT CTGAGCTCTC TGTGTGCACT GAGTGATGTC 
ACTATATCTA CCTGCCATGT GTCTGCAAGC ATTGGGACTC GACTGGTGTT GGACCATAAT 
GGGAAAATCA TCCAGAAAAC TCCCTGCCCA CGGCCTAAAG GAACCACAGT CAGCGTGCAG 
AACTTATTTT ACACCCTACC CGTACGTCAC AAAGAGTTTC AAAGGAACAT TAAAAAGGAG 
TATGCCAAAA TGGTCCAGGT CTTACAGGCG TACTGCATCA TTTCAGCCGG CATCCGTGTG 
AGCTGCACTA ATCAGCTCGG ACAGGGGAAA CGGCAGCCTG TGGTGTGCAC GAGCGGAAGC 
TCCGGCATGA AGGAAAATAT CGGGTCTGTG TTCGGCCAGA AGCAGCTGCA GAGCCTCGTT 
CCTTTTGTGC AGCTGCCCCC TAGTGACTCC GTCTGTGAAG AGTACTGCCT GAGCGCTTGT 
GGGACCCCGC AGAGTCCTTT CCGCATTTCA GGCTTCATTT CACAGTGCAC GCATGGTGCC 
GGGAGGAGTT CAACAGACAG ACAGTTTTTC TTCATCAATC AGCGGCCTTG TGACCCAGCG 
AAGGTCTCTA GACTGGTGAA TGAGGTCTAC CACATGTATA ATCGGCACCA GTATCCATTT 
GTCGTTCTTA ACGTGTCCGT GGACTCGGAA TGTGTGGATA TTAACGTGAC CCCAGATAAA 
AGGCAGATTT TACTACAGGA AGAGAAGCTT TTGCTGGCAG TTTTAAAGAC GTCCTTGATG 
GGAATGTTCG ACAGTGATGC AAACAAGCTT AGTGTCAACC AGCAGCCGCT GCTGAATGTC 
GAAGGTAACT TAGTAAAGCT ACATACCGCA GAAGTAGGAG AGCAAGAGAA CTCTCCTTCA 
TTGAGGATCA CAGCGGAAGA GAAAAGGGTA GCATCTGTGT CTAGGCTGAG AGAGGCCTAT 
TCTCTTCATC GTACCACAGA GACCAAGTCT TGGGGCCCAG AGACTCCTGA ACTGAAACAG 
AGTTTTCCAA GTCAGAAAAG GGGTGTATCA TCATCTTGTC CTTCAGACAT CATCTCTTAT 
AGAGGCCTGT GTGGCTCACA GGACAAATTG GTGAGTCCCA CGGATAGCCC TGGTGACTGT 
ATGGACAGAG AAAAAGGAGA AAAGGACTCA GGGCTTAGCA GCACCTCAGC TGGCTCTGAG 
GAAGGGTTCA GCACCCCAGA AGTGGCCAGT AGCTTTAGCA GTGACTGCAA CGTGAGCTCC 
CCAGAGGACA GACCTTCTCA GGAAAACACA AACTGTGGCG AGCAGTTCCT TGAAGTGGAT 
GACCACCTTT CAGGTACAGG ACACCATTTG AAGCCAGAAG ACAATGGATA TAAATGTCGA 
GCTTCACTTC CACCAACTCG GCTCTCTCCC TCAAATGCTA AGCGTTTCAG GACAGAGGAC 
AGGCCTTCAA ATGTTGGCGT TCCTCAGAAC ACCTCAGCAG CTGAGGTTGA CGTAGCTGTA 
AAAATTAATA AGAAAATAGT GCTCCTTGAC TTCTCTCTGA GCTCTTTAGC TAAACAAATG 
AAGCAGTTAC AGCACCTGAA GCAGCAGAGC AAAAGCGAAC ACAATTACAG GAAATTTAGG 
GCCAAGATTT GCCCTGGAGA AAATCAAGCA GCAGAAGATG AACTCAGAAG AGAGATTAGG 
AAGTCGATGT TCGCAGAGAT GGAGATCTTG GGTCAGTTTA ACCTGGGATT CATCGTAACC 
AAACTGAAGG AGGACCTCTT CCTGGTGGAC CAGCACGCCG CCGACGAGAA GTACAACTTT 
GAGATGCTGC AGCAGCACAC GGTGCTCCAG GCTCAGAGGC TCATCACTCC CCAGACTCTG 
AACTTAACTG CTGTCAATGA AGCTGTGCTG ATAGAAAATC TGGAAATATT CAGAAAGAAT 
GGCTTTGACT TTATCATTGA TGAAGATGCT CCAGTCACTG AAAGGGCTAA ACTGATTTCC 
TTACCCACTA GTAAAAACTG GACCTTTGGA CCCCAAGATA TCGATGAACT GATCTTTATG 
CTCAGTGACA GCCCTGGGGT CATGTGCCGG CCCTCGAGAG TCAGACAGAT GTTTGCTTCC 
CGAGCGTGTC GGAAGTCTGT GATGATTGGA ACCGCTCTCA GTGCAAGTGA GATGAAGAAG 
CTCATCTCCC ACATGGGTGA GATGGACCAC CCCTGGAACT GCCCCCACGG AAGGCCGACC 
ATGAGGCACA TTGCAAATCT GGATGTCATC TCCCAGAACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006248924.1
CDS	104..2665
Translation	MEPTEGASTECAKAIKPIDGKSVHQICSGQVVLSLSTAVKELIENSVDAGATSIDLRLKDYGVDLIEVSDNGCGVEEENFEGLALKHHTSKIREFADLTQVETFGFRGEALSSLCALSDVTISTCHVSASIGTRLVLDHNGKIIQKTPCPRPKGTTVSVQNLFYTLPVRHKEFQRNIKKEYAKMVQVLQAYCIISAGIRVSCTNQLGQGKRQPVVCTSGSSGMKENIGSVFGQKQLQSLVPFVQLPPSDSVCEEYCLSACGTPQSPFRISGFISQCTHGAGRSSTDRQFFFINQRPCDPAKVSRLVNEVYHMYNRHQYPFVVLNVSVDSECVDINVTPDKRQILLQEEKLLLAVLKTSLMGMFDSDANKLSVNQQPLLNVEGNLVKLHTAEVGEQENSPSLRITAEEKRVASVSRLREAYSLHRTTETKSWGPETPELKQSFPSQKRGVSSSCPSDIISYRGLCGSQDKLVSPTDSPGDCMDREKGEKDSGLSSTSAGSEEGFSTPEVASSFSSDCNVSSPEDRPSQENTNCGEQFLEVDDHLSGTGHHLKPEDNGYKCRASLPPTRLSPSNAKRFRTEDRPSNVGVPQNTSAAEVDVAVKINKKIVLLDFSLSSLAKQMKQLQHLKQQSKSEHNYRKFRAKICPGENQAAEDELRREIRKSMFAEMEILGQFNLGFIVTKLKEDLFLVDQHAADEKYNFEMLQQHTVLQAQRLITPQTLNLTAVNEAVLIENLEIFRKNGFDFIIDEDAPVTERAKLISLPTSKNWTFGPQDIDELIFMLSDSPGVMCRPSRVRQMFASRACRKSVMIGTALSASEMKKLISHMGEMDHPWNCPHGRPTMRHIANLDVISQN

Target ORF information:

RefSeq Version	XM_006248862.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus PMS1 homolog 2, mismatch repair system component (Pms2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006248862.3

ORF Insert Sequence:

ATGGAACCAA CTGAGGGCGC GAGTACAGAA TGTGCTAAGG CCATCAAGCC TATTGATGGG 
AAGTCAGTCC ATCAGATTTG CTCTGGGCAG GTGGTACTCA GTTTAAGCAC TGCTGTGAAG 
GAGTTGATAG AAAATAGTGT AGATGCCGGT GCTACTAGTA TTGATCTAAG GCTTAAAGAC 
TATGGAGTGG ACCTCATTGA AGTTTCAGAC AATGGATGTG GGGTAGAAGA AGAAAACTTT 
GAAGGTCTAG CTCTGAAACA TCACACCTCT AAGATTCGAG AGTTTGCCGA CCTCACGCAG 
GTTGAAACTT TCGGCTTTCG GGGGGAAGCT CTGAGCTCTC TGTGTGCACT GAGTGATGTC 
ACTATATCTA CCTGCCATGT GTCTGCAAGC ATTGGGACTC GACTGGTGTT GGACCATAAT 
GGGAAAATCA TCCAGAAAAC TCCCTGCCCA CGGCCTAAAG GAACCACAGT CAGCGTGCAG 
AACTTATTTT ACACCCTACC CGTACGTCAC AAAGAGTTTC AAAGGAACAT TAAAAAGGAG 
TATGCCAAAA TGGTCCAGGT CTTACAGGCG TACTGCATCA TTTCAGCCGG CATCCGTGTG 
AGCTGCACTA ATCAGCTCGG ACAGGGGAAA CGGCAGCCTG TGGTGTGCAC GAGCGGAAGC 
TCCGGCATGA AGGAAAATAT CGGGTCTGTG TTCGGCCAGA AGCAGCTGCA GAGCCTCGTT 
CCTTTTGTGC AGCTGCCCCC TAGTGACTCC GTCTGTGAAG AGTACTGCCT GAGCGCTTGT 
GGGACCCCGC AGAGTCCTTT CCGCATTTCA GGCTTCATTT CACAGTGCAC GCATGGTGCC 
GGGAGGAGTT CAACAGACAG ACAGTTTTTC TTCATCAATC AGCGGCCTTG TGACCCAGCG 
AAGGTCTCTA GACTGGTGAA TGAGGTCTAC CACATGTATA ATCGGCACCA GTATCCATTT 
GTCGTTCTTA ACGTGTCCGT GGACTCGGAA TGTGTGGATA TTAACGTGAC CCCAGATAAA 
AGGCAGATTT TACTACAGGA AGAGAAGCTT TTGCTGGCAG TTTTAAAGAC GTCCTTGATG 
GGAATGTTCG ACAGTGATGC AAACAAGCTT AGTGTCAACC AGCAGCCGCT GCTGAATGTC 
GAAGGTAACT TAGTAAAGCT ACATACCGCA GAAGTAGGAG AGCAAGAGAA CTCTCCTTCA 
TTGAGGATCA CAGCGGAAGA GAAAAGGGTA GCATCTGTGT CTAGGCTGAG AGAGGCCTAT 
TCTCTTCATC GTACCACAGA GACCAAGTCT TGGGGCCCAG AGACTCCTGA ACTGAAACAG 
AGTTTTCCAA GTCAGAAAAG GGGTGTATCA TCATCTTGTC CTTCAGACAT CATCTCTTAT 
AGAGGCCTGT GTGGCTCACA GGACAAATTG GTGAGTCCCA CGGATAGCCC TGGTGACTGT 
ATGGACAGAG AAAAAGGAGA AAAGGACTCA GGGCTTAGCA GCACCTCAGC TGGCTCTGAG 
GAAGGGTTCA GCACCCCAGA AGTGGCCAGT AGCTTTAGCA GTGACTGCAA CGTGAGCTCC 
CCAGAGGACA GACCTTCTCA GGAAAACACA AACTGTGGCG AGCAGTTCCT TGAAGTGGAT 
GACCACCTTT CAGGTACAGG ACACCATTTG AAGCCAGAAG ACAATGGATA TAAATGTCGA 
GCTTCACTTC CACCAACTCG GCTCTCTCCC TCAAATGCTA AGCGTTTCAG GACAGAGGAC 
AGGCCTTCAA ATGTTGGCGT TCCTCAGAAC ACCTCAGCAG CTGAGGTTGA CGTAGCTGTA 
AAAATTAATA AGAAAATAGT GCTCCTTGAC TTCTCTCTGA GCTCTTTAGC TAAACAAATG 
AAGCAGTTAC AGCACCTGAA GCAGCAGAGC AAAAGCGAAC ACAATTACAG GAAATTTAGG 
GCCAAGATTT GCCCTGGAGA AAATCAAGCA GCAGAAGATG AACTCAGAAG AGAGATTAGG 
AAGTCGATGT TCGCAGAGAT GGAGATCTTG GGTCAGTTTA ACCTGGGATT CATCGTAACC 
AAACTGAAGG AGGACCTCTT CCTGGTGGAC CAGCACGCCG CCGACGAGAA GTACAACTTT 
GAGATGCTGC AGCAGCACAC GGTGCTCCAG GCTCAGAGGC TCATCACTCC CCAGACTCTG 
AACTTAACTG CTGTCAATGA AGCTGTGCTG ATAGAAAATC TGGAAATATT CAGAAAGAAT 
GGCTTTGACT TTATCATTGA TGAAGATGCT CCAGTCACTG AAAGGGCTAA ACTGATTTCC 
TTACCCACTA GTAAAAACTG GACCTTTGGA CCCCAAGATA TCGATGAACT GATCTTTATG 
CTCAGTGACA GCCCTGGGGT CATGTGCCGG CCCTCGAGAG TCAGACAGAT GTTTGCTTCC 
CGAGCGTGTC GGAAGTCTGT GATGATTGGA ACCGCTCTCA GTGCAAGTGA GATGAAGAAG 
CTCATCTCCC ACATGGGTGA GATGGACCAC CCCTGGAACT GCCCCCACGG AAGGCCGACC 
ATGAGGCACA TTGCAAATCT GGATGTCATC TCCCAGAACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pms2 ( XM_017598288.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017453777.1 Rattus norvegicus PMS1 homolog 2, mismatch repair system component (Pms2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa57793
Clone ID Related Accession (Same CDS sequence)	XM_017598288.1
Accession Version	XM_017598288.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2013bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	mismatch repair endonuclease PMS2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005111.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTCCAGG TCTTACAGGC GTACTGCATC ATTTCAGCCG GCATCCGTGT GAGCTGCACT 
AATCAGCTCG GACAGGGGAA ACGGCAGCCT GTGGTGTGCA CGAGCGGAAG CTCCGGCATG 
AAGGAAAATA TCGGGTCTGT GTTCGGCCAG AAGCAGCTGC AGAGCCTCGT TCCTTTTGTG 
CAGCTGCCCC CTAGTGACTC CGTCTGTGAA GAGTACTGCC TGAGCGCTTG TGGGACCCCG 
CAGAGTCCTT TCCGCATTTC AGGCTTCATT TCACAGTGCA CGCATGGTGC CGGGAGGAGT 
TCAACAGACA GACAGTTTTT CTTCATCAAT CAGCGGCCTT GTGACCCAGC GAAGGTCTCT 
AGACTGGTGA ATGAGGTCTA CCACATGTAT AATCGGCACC AGTATCCATT TGTCGTTCTT 
AACGTGTCCG TGGACTCGGA ATGTGTGGAT ATTAACGTGA CCCCAGATAA AAGGCAGATT 
TTACTACAGG AAGAGAAGCT TTTGCTGGCA GTTTTAAAGA CGTCCTTGAT GGGAATGTTC 
GACAGTGATG CAAACAAGCT TAGTGTCAAC CAGCAGCCGC TGCTGAATGT CGAAGGTAAC 
TTAGTAAAGC TACATACCGC AGAAGTAGGA GAGCAAGAGA ACTCTCCTTC ATTGAGGATC 
ACAGCGGAAG AGAAAAGGGT AGCATCTGTG TCTAGGCTGA GAGAGGCCTA TTCTCTTCAT 
CGTACCACAG AGACCAAGTC TTGGGGCCCA GAGACTCCTG AACTGAAACA GAGTTTTCCA 
AGTCAGAAAA GGGGTGTATC ATCATCTTGT CCTTCAGACA TCATCTCTTA TAGAGGCCTG 
TGTGGCTCAC AGGACAAATT GGTGAGTCCC ACGGATAGCC CTGGTGACTG TATGGACAGA 
GAAAAAGGAG AAAAGGACTC AGGGCTTAGC AGCACCTCAG CTGGCTCTGA GGAAGGGTTC 
AGCACCCCAG AAGTGGCCAG TAGCTTTAGC AGTGACTGCA ACGTGAGCTC CCCAGAGGAC 
AGACCTTCTC AGGAAAACAC AAACTGTGGC GAGCAGTTCC TTGAAGTGGA TGACCACCTT 
TCAGGTACAG GACACCATTT GAAGCCAGAA GACAATGGAT ATAAATGTCG AGCTTCACTT 
CCACCAACTC GGCTCTCTCC CTCAAATGCT AAGCGTTTCA GGACAGAGGA CAGGCCTTCA 
AATGTTGGCG TTCCTCAGAA CACCTCAGCA GCTGAGGTTG ACGTAGCTGT AAAAATTAAT 
AAGAAAATAG TGCTCCTTGA CTTCTCTCTG AGCTCTTTAG CTAAACAAAT GAAGCAGTTA 
CAGCACCTGA AGCAGCAGAG CAAAAGCGAA CACAATTACA GGAAATTTAG GGCCAAGATT 
TGCCCTGGAG AAAATCAAGC AGCAGAAGAT GAACTCAGAA GAGAGATTAG GAAGTCGATG 
TTCGCAGAGA TGGAGATCTT GGGTCAGTTT AACCTGGGAT TCATCGTAAC CAAACTGAAG 
GAGGACCTCT TCCTGGTGGA CCAGCACGCC GCCGACGAGA AGTACAACTT TGAGATGCTG 
CAGCAGCACA CGGTGCTCCA GGCTCAGAGG CTCATCACTC CCCAGACTCT GAACTTAACT 
GCTGTCAATG AAGCTGTGCT GATAGAAAAT CTGGAAATAT TCAGAAAGAA TGGCTTTGAC 
TTTATCATTG ATGAAGATGC TCCAGTCACT GAAAGGGCTA AACTGATTTC CTTACCCACT 
AGTAAAAACT GGACCTTTGG ACCCCAAGAT ATCGATGAAC TGATCTTTAT GCTCAGTGAC 
AGCCCTGGGG TCATGTGCCG GCCCTCGAGA GTCAGACAGA TGTTTGCTTC CCGAGCGTGT 
CGGAAGTCTG TGATGATTGG AACCGCTCTC AGTGCAAGTG AGATGAAGAA GCTCATCTCC 
CACATGGGTG AGATGGACCA CCCCTGGAAC TGCCCCCACG GAAGGCCGAC CATGAGGCAC 
ATTGCAAATC TGGATGTCAT CTCCCAGAAC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017453777.1
CDS	611..2623
Translation	MVQVLQAYCIISAGIRVSCTNQLGQGKRQPVVCTSGSSGMKENIGSVFGQKQLQSLVPFVQLPPSDSVCEEYCLSACGTPQSPFRISGFISQCTHGAGRSSTDRQFFFINQRPCDPAKVSRLVNEVYHMYNRHQYPFVVLNVSVDSECVDINVTPDKRQILLQEEKLLLAVLKTSLMGMFDSDANKLSVNQQPLLNVEGNLVKLHTAEVGEQENSPSLRITAEEKRVASVSRLREAYSLHRTTETKSWGPETPELKQSFPSQKRGVSSSCPSDIISYRGLCGSQDKLVSPTDSPGDCMDREKGEKDSGLSSTSAGSEEGFSTPEVASSFSSDCNVSSPEDRPSQENTNCGEQFLEVDDHLSGTGHHLKPEDNGYKCRASLPPTRLSPSNAKRFRTEDRPSNVGVPQNTSAAEVDVAVKINKKIVLLDFSLSSLAKQMKQLQHLKQQSKSEHNYRKFRAKICPGENQAAEDELRREIRKSMFAEMEILGQFNLGFIVTKLKEDLFLVDQHAADEKYNFEMLQQHTVLQAQRLITPQTLNLTAVNEAVLIENLEIFRKNGFDFIIDEDAPVTERAKLISLPTSKNWTFGPQDIDELIFMLSDSPGVMCRPSRVRQMFASRACRKSVMIGTALSASEMKKLISHMGEMDHPWNCPHGRPTMRHIANLDVISQN

Target ORF information:

RefSeq Version	XM_017598288.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus PMS1 homolog 2, mismatch repair system component (Pms2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017598288.1

ORF Insert Sequence:

ATGGTCCAGG TCTTACAGGC GTACTGCATC ATTTCAGCCG GCATCCGTGT GAGCTGCACT 
AATCAGCTCG GACAGGGGAA ACGGCAGCCT GTGGTGTGCA CGAGCGGAAG CTCCGGCATG 
AAGGAAAATA TCGGGTCTGT GTTCGGCCAG AAGCAGCTGC AGAGCCTCGT TCCTTTTGTG 
CAGCTGCCCC CTAGTGACTC CGTCTGTGAA GAGTACTGCC TGAGCGCTTG TGGGACCCCG 
CAGAGTCCTT TCCGCATTTC AGGCTTCATT TCACAGTGCA CGCATGGTGC CGGGAGGAGT 
TCAACAGACA GACAGTTTTT CTTCATCAAT CAGCGGCCTT GTGACCCAGC GAAGGTCTCT 
AGACTGGTGA ATGAGGTCTA CCACATGTAT AATCGGCACC AGTATCCATT TGTCGTTCTT 
AACGTGTCCG TGGACTCGGA ATGTGTGGAT ATTAACGTGA CCCCAGATAA AAGGCAGATT 
TTACTACAGG AAGAGAAGCT TTTGCTGGCA GTTTTAAAGA CGTCCTTGAT GGGAATGTTC 
GACAGTGATG CAAACAAGCT TAGTGTCAAC CAGCAGCCGC TGCTGAATGT CGAAGGTAAC 
TTAGTAAAGC TACATACCGC AGAAGTAGGA GAGCAAGAGA ACTCTCCTTC ATTGAGGATC 
ACAGCGGAAG AGAAAAGGGT AGCATCTGTG TCTAGGCTGA GAGAGGCCTA TTCTCTTCAT 
CGTACCACAG AGACCAAGTC TTGGGGCCCA GAGACTCCTG AACTGAAACA GAGTTTTCCA 
AGTCAGAAAA GGGGTGTATC ATCATCTTGT CCTTCAGACA TCATCTCTTA TAGAGGCCTG 
TGTGGCTCAC AGGACAAATT GGTGAGTCCC ACGGATAGCC CTGGTGACTG TATGGACAGA 
GAAAAAGGAG AAAAGGACTC AGGGCTTAGC AGCACCTCAG CTGGCTCTGA GGAAGGGTTC 
AGCACCCCAG AAGTGGCCAG TAGCTTTAGC AGTGACTGCA ACGTGAGCTC CCCAGAGGAC 
AGACCTTCTC AGGAAAACAC AAACTGTGGC GAGCAGTTCC TTGAAGTGGA TGACCACCTT 
TCAGGTACAG GACACCATTT GAAGCCAGAA GACAATGGAT ATAAATGTCG AGCTTCACTT 
CCACCAACTC GGCTCTCTCC CTCAAATGCT AAGCGTTTCA GGACAGAGGA CAGGCCTTCA 
AATGTTGGCG TTCCTCAGAA CACCTCAGCA GCTGAGGTTG ACGTAGCTGT AAAAATTAAT 
AAGAAAATAG TGCTCCTTGA CTTCTCTCTG AGCTCTTTAG CTAAACAAAT GAAGCAGTTA 
CAGCACCTGA AGCAGCAGAG CAAAAGCGAA CACAATTACA GGAAATTTAG GGCCAAGATT 
TGCCCTGGAG AAAATCAAGC AGCAGAAGAT GAACTCAGAA GAGAGATTAG GAAGTCGATG 
TTCGCAGAGA TGGAGATCTT GGGTCAGTTT AACCTGGGAT TCATCGTAAC CAAACTGAAG 
GAGGACCTCT TCCTGGTGGA CCAGCACGCC GCCGACGAGA AGTACAACTT TGAGATGCTG 
CAGCAGCACA CGGTGCTCCA GGCTCAGAGG CTCATCACTC CCCAGACTCT GAACTTAACT 
GCTGTCAATG AAGCTGTGCT GATAGAAAAT CTGGAAATAT TCAGAAAGAA TGGCTTTGAC 
TTTATCATTG ATGAAGATGC TCCAGTCACT GAAAGGGCTA AACTGATTTC CTTACCCACT 
AGTAAAAACT GGACCTTTGG ACCCCAAGAT ATCGATGAAC TGATCTTTAT GCTCAGTGAC 
AGCCCTGGGG TCATGTGCCG GCCCTCGAGA GTCAGACAGA TGTTTGCTTC CCGAGCGTGT 
CGGAAGTCTG TGATGATTGG AACCGCTCTC AGTGCAAGTG AGATGAAGAA GCTCATCTCC 
CACATGGGTG AGATGGACCA CCCCTGGAAC TGCCCCCACG GAAGGCCGAC CATGAGGCAC 
ATTGCAAATC TGGATGTCAT CTCCCAGAAC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Refining the role of PMS2 in Lynch syndrome: germline mutational analysis improved by comprehensive assessment of variants.
Journal of medical genetics50(8)552-63(2013 Aug)
Borr?s E,Pineda M,Cadi?anos J,Del Valle J,Brieger A,Hinrichsen I,Cabanillas R,Navarro M,Brunet J,Sanjuan X,Musulen E,van der Klift H,L?zaro C,Plotz G,Blanco I,Capell? G

Pms2 suppresses large expansions of the (GAA?TTC)n sequence in neuronal tissues.
PloS one7(10)e47085(2012)
Bourn RL,De Biase I,Pinto RM,Sandi C,Al-Mahdawi S,Pook MA,Bidichandani SI

Genetic susceptibility to distinct bladder cancer subphenotypes.
European urology57(2)283-92(2010 Feb)
Guey LT,Garc?a-Closas M,Murta-Nascimento C,Lloreta J,Palencia L,Kogevinas M,Rothman N,Vellalta G,Calle ML,Marenne G,Tard?n A,Carrato A,Garc?a-Closas R,Serra C,Silverman DT,Chanock S,Real FX,Malats N,

The elevated expression of a mismatch repair protein is a predictor for biochemical recurrence after radical prostatectomy.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology18(1)57-64(2009 Jan)
Norris AM,Gentry M,Peehl DM,D'Agostino R Jr,Scarpinato KD

Mismatch repair gene polymorphisms and survival in invasive ovarian cancer patients.
European journal of cancer (Oxford, England : 1990)44(15)2259-65(2008 Oct)
Mann A,Hogdall E,Ramus SJ,DiCioccio RA,Hogdall C,Quaye L,McGuire V,Whittemore AS,Shah M,Greenberg D,Easton DF,Ponder BA,Kjaer SK,Gayther SA,Thompson DJ,Pharoah PD,Song H

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Pms2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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