Ccl6 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ccl6
Entrez Gene ID	287910
Full Name	chemokine (C-C motif) ligand 6
Synonyms	Mrp-1,Scay6
General protein information	Preferred Names chemokine (C-C motif) ligand 6 Names C-C motif chemokine 6 chemokine ligand 6 small-inducible cytokine A6
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q26

mRNA and Protein(s)

mRNA	Protein	Name
NM_001004202.2	NP_001004202.1	C-C motif chemokine 6 precursor

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Ccl6	NP_033165.1
Rattus norvegicus (Norway rat)	Ccl6	NP_001004202.1

Gene Ontology
Bibliography

Related articles in PubMed

Molecular cloning and functional characterization of a mouse ccl6 analog gene in the rat.
Jiang N, Zheng YH, Chen XJ, Qiu C, Zhang XF, Wen SH, Bian GX
Genetics and molecular research : GMR11(4)3889-98(2012 Nov)

Fine-mapping and comprehensive transcript analysis reveals nonsynonymous variants within a novel 1.17 Mb blood pressure QTL region on rat chromosome 10.
Saad Y, Garrett MR, Manickavasagam E, Yerga-Woolwine S, Farms P, Radecki T, Joe B
Genomics89(3)343-53(2007 Mar)

Functional expression of CCL6 by rat microglia: a possible role of CCL6 in cell-cell communication.
Kanno M, Suzuki S, Fujiwara T, Yokoyama A, Sakamoto A, Takahashi H, Imai Y, Tanaka J
Journal of neuroimmunology167(1-2)72-80(2005 Oct)

The CCL6 chemokine is differentially regulated by c-Myc and L-Myc, and promotes tumorigenesis and metastasis.
Yi F, Jaffe R, Prochownik EV
Cancer research63(11)2923-32(2003 Jun)

Selective binding of the truncated form of the chemokine CKbeta8 (25-99) to CC chemokine receptor 1(CCR1).
Berkhout TA, Gohil J, Gonzalez P, Nicols CL, Moores KE, Macphee CH, White JR, Groot PH
Biochemical pharmacology59(5)591-6(2000 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The mouse C10 analog gene in the rat, and named it as ccl6, was identified and cloned.
Title: Molecular cloning and functional characterization of a mouse ccl6 analog gene in the rat.

The following Ccl6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ccl6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa10060	NM_001004202.2 Latest version!	Rattus norvegicus chemokine (C-C motif) ligand 6 (Ccl6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
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30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ccl6 ( NM_001004202.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001004202.1 Rattus norvegicus chemokine (C-C motif) ligand 6 (Ccl6), mRNA.

Price & Availability↑

CloneID	ORa10060
Clone ID Related Accession (Same CDS sequence)	NM_001004202.2
Accession Version	NM_001004202.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 348bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-22
Organism	Rattus norvegicus(Norway rat)
Product	C-C motif chemokine 6 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from EF121993.1. On Jun 10, 2007 this sequence version replaced NM_001004202.1. ##Evidence-Data-START## Transcript exon combination :: EF121992.1, EF121993.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01906350, SAMN01906351 [ECO:0000348] ##Evidence-Data-END##

ATGAGACATT CCAAGACTGC CATTTCATTC TTTATCCTTG TGGCCGTCCT TGGGTCCCAG 
GCTGGGCTCA TACAAGATAC GGTAAAAGAA GATCGTCCCT TTAATCCTAC AATAATTCAC 
CAAGGCTTTC AAGACTCTTC AGACTGCTGC TTCTCCTATG CCTCACAGAT CCCATGTTCA 
AGATTTATAT ATTATTTTCC AACCAGTGGT GGGTGCACCA AGCCAGGCAT CATCTTTGTC 
ACCAGGAAGA GGAAGCGGGT CTGTGCCAAC CCGAGTGATC AGAGAGTTCA GACGTGCATA 
AGCACCCTGA AGCTAGGCCC AAGATCTGGG AACAGTGCCA TTGCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001004202.1
CDS	1..348
Translation	MRHSKTAISFFILVAVLGSQAGLIQDTVKEDRPFNPTIIHQGFQDSSDCCFSYASQIPCSRFIYYFPTSGGCTKPGIIFVTRKRKRVCANPSDQRVQTCISTLKLGPRSGNSAIA

Target ORF information:

RefSeq Version	NM_001004202.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus chemokine (C-C motif) ligand 6 (Ccl6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001004202.2

ORF Insert Sequence:

ATGAGACATT CCAAGACTGC CATTTCATTC TTTATCCTTG TGGCCGTCCT TGGGTCCCAG 
GCTGGGCTCA TACAAGATAC GGTAAAAGAA GATCGTCCCT TTAATCCTAC AATAATTCAC 
CAAGGCTTTC AAGACTCTTC AGACTGCTGC TTCTCCTATG CCTCACAGAT CCCATGTTCA 
AGATTTATAT ATTATTTTCC AACCAGTGGT GGGTGCACCA AGCCAGGCAT CATCTTTGTC 
ACCAGGAAGA GGAAGCGGGT CTGTGCCAAC CCGAGTGATC AGAGAGTTCA GACGTGCATA 
AGCACCCTGA AGCTAGGCCC AAGATCTGGG AACAGTGCCA TTGCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Molecular cloning and functional characterization of a mouse ccl6 analog gene in the rat.
Genetics and molecular research : GMR11(4)3889-98(2012 Nov)
Jiang N,Zheng YH,Chen XJ,Qiu C,Zhang XF,Wen SH,Bian GX

Fine-mapping and comprehensive transcript analysis reveals nonsynonymous variants within a novel 1.17 Mb blood pressure QTL region on rat chromosome 10.
Genomics89(3)343-53(2007 Mar)
Saad Y,Garrett MR,Manickavasagam E,Yerga-Woolwine S,Farms P,Radecki T,Joe B

Functional expression of CCL6 by rat microglia: a possible role of CCL6 in cell-cell communication.
Journal of neuroimmunology167(1-2)72-80(2005 Oct)
Kanno M,Suzuki S,Fujiwara T,Yokoyama A,Sakamoto A,Takahashi H,Imai Y,Tanaka J

The CCL6 chemokine is differentially regulated by c-Myc and L-Myc, and promotes tumorigenesis and metastasis.
Cancer research63(11)2923-32(2003 Jun)
Yi F,Jaffe R,Prochownik EV

Selective binding of the truncated form of the chemokine CKbeta8 (25-99) to CC chemokine receptor 1(CCR1).
Biochemical pharmacology59(5)591-6(2000 Mar)
Berkhout TA,Gohil J,Gonzalez P,Nicols CL,Moores KE,Macphee CH,White JR,Groot PH