Cops2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cops2
Entrez Gene ID	261736
Full Name	COP9 signalosome subunit 2
Synonyms	CSN2,Trip15
General protein information	Preferred Names COP9 signalosome subunit 2 Names COP9 signalosome complex subunit 2 COP9 (constitutive photomorphogenic) homolog, subunit 2 JAB1-containing signalosome subunit 2 SGN2 TR-interacting protein 15 TRIP-15 alien homolog signalosome subunit 2 thyroid receptor-interacting protein 15 tyroid receptor interacting protein 15
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 3 Map Location: 3q36
Summary	transcriptional corepressor that may be involved in neural differentiation [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006234901.3	XP_006234963.1	COP9 signalosome complex subunit 2 isoform X1
XM_008762146.2	XP_008760368.1	COP9 signalosome complex subunit 2 isoform X2
NM_153297.1	NP_695209.1	COP9 signalosome complex subunit 2

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Cops2	NP_695209.1
Drosophila melanogaster (fruit fly)	alien	NP_001260276.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP008598	XP_314698.1
	LOC699342	XP_001089276.1
Bos taurus (cattle)	COPS2	XP_005211948.1
Mus musculus (house mouse)	Cops2	NP_001272436.1
Danio rerio (zebrafish)	cops2	NP_001002055.1
Arabidopsis thaliana (thale cress)	FUS12	NP_565632.1
Canis lupus familiaris (dog)	COPS2	XP_005638452.1
Gallus gallus (chicken)	COPS2	NP_001026767.1
Caenorhabditis elegans (roundworm)	csn-2	NP_491740.1
Oryza sativa (rice)	Os01g0279200	NP_001042746.1
Xenopus tropicalis (tropical clawed frog)	cops2	NP_001015820.1

Gene Ontology
Bibliography

Related articles in PubMed

Analysis of early C2C12 myogenesis identifies stably and differentially expressed transcriptional regulators whose knock-down inhibits myoblast differentiation.
Rajan S, Chu Pham Dang H, Djambazian H, Zuzan H, Fedyshyn Y, Ketela T, Moffat J, Hudson TJ, Sladek R
Physiological genomics44(2)183-97(2012 Feb)

Symmetrical modularity of the COP9 signalosome complex suggests its multifunctionality.
Sharon M, Mao H, Boeri Erba E, Stephens E, Zheng N, Robinson CV
Structure (London, England : 1993)17(1)31-40(2009 Jan)

Characterization of the human COP9 signalosome complex using affinity purification and mass spectrometry.
Fang L, Wang X, Yamoah K, Chen PL, Pan ZQ, Huang L
Journal of proteome research7(11)4914-25(2008 Nov)

Mixed lineage kinase 2 enhances trans-repression of Alien and nuclear receptors.
Eckey M, Tenbaum SP, Mu?oz A, Baniahmad A
Molecular and cellular endocrinology213(1)71-8(2003 Dec)

Disruption of the COP9 signalosome Csn2 subunit in mice causes deficient cell proliferation, accumulation of p53 and cyclin E, and early embryonic death.
Lykke-Andersen K, Schaefer L, Menon S, Deng XW, Miller JB, Wei N
Molecular and cellular biology23(19)6790-7(2003 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Expressed at an early stage of neuronal differentiaation.
Title: Implication of Trip15/CSN2 in early stage of neuronal differentiation of P19 embryonal carcinoma cells.

The following Cops2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cops2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa44496	XM_008762146.2 Latest version!	Rattus norvegicus COP9 signalosome subunit 2 (Cops2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
ORa02944	NM_153297.1 Latest version!	Rattus norvegicus COP9 signalosome subunit 2 (Cops2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa26306	XM_006234901.3 Latest version!	Rattus norvegicus COP9 signalosome subunit 2 (Cops2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cops2 ( XM_008762146.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008760368.1 Rattus norvegicus COP9 signalosome subunit 2 (Cops2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa44496
Clone ID Related Accession (Same CDS sequence)	XM_008762146.2
Accession Version	XM_008762146.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1209bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	COP9 signalosome complex subunit 2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008762146.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCTGACA TGGAGGATGA TTTCATGTGC GATGATGAGG AGGACTACGA CCTGGAATAC 
TCTGAAGACA GTAACTCTGA GCCCAACGTG GATTTGGAAA ATCAGTACTA TAATTCCAAA 
GCACTGAAAG AAGATGACCC GAAAGCAGCA CTAAGCAGCT TCCAAAAGGT TTTGGAACTC 
GAAGGTGAGA AGGGAGAATG GGGATTCAAA GCGCTAAAAC AGATGATCAA GATTAACTTC 
AAGCTGACAA ACTTTCCAGA AATGATGAAC AGATATAAGC AACTATTGAC CTATATTCGG 
AGTGCAGTCA CCAGGAACTA CTCTGAAAAG TCTATTAACT CTATCCTTGA CTATATCTCC 
ACTTCTAAAC AGAATTCTGA TTTTTTATGT CAGATGGATT TACTGCAGGA ATTTTATGAA 
ACAACACTGG AAGCTTTGAA AGATGCTAAG AATGATAGAC TGTGGTTTAA GACAAACACA 
AAGCTTGGAA AATTATATTT AGAACGAGAA GAATATGGAA AGCTTCAAAA AATTTTACGC 
CAGTTACATC AGTCTTGTCA GACTGATGAT GGAGAAGATG ACCTGAAAAA AGAATGTGGT 
GGTAAGATGC ACTTGAGAGA AGGTGAATTT GAAAAGGCAC ACACTGATTT TTTTGAAGCT 
TTCAAGAATT ATGATGAATC AGGAAGCCCA AGACGAACCA CTTGTTTAAA ATATTTGGTC 
TTAGCAAATA TGCTAATGAA ATCAGGAATA AATCCATTTG ACTCGCAAGA GGCCAAGCCG 
TATAAAAATG ATCCAGAAAT TCTAGCAATG ACAAATTTAG TAAGTGCCTA TCAGAACAAT 
GACATCACCG AGTTTGAAAA GATTCTGAAA ACAAATCACA GCAACATCAT GGATGATCCT 
TTCATAAGAG AACACATTGA AGAGCTTTTA CGAAACATCA GAACACAAGT CCTCATAAAG 
TTAATTAAGC CTTACACAAG AATACATATT CCTTTTATTT CTAAGGAGCT AAACATAGAC 
GTAGCTGATG TGGAAAGCTT GCTGGTGCAG TGCATACTGG ATAACACTAT TCATGGCCGA 
ATTGATCAAG TCAACCAGCT CCTTGAACTG GATCATCAGA AGAGGGGCGG TGCCCGATAT 
ACTGCACTAG ATAAATGGAC CAACCAACTA AACTCTCTGA ACCAGGCTGT GGTCAGTAAA 
CTGGCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008760368.1
CDS	45..1253
Translation	MSDMEDDFMCDDEEDYDLEYSEDSNSEPNVDLENQYYNSKALKEDDPKAALSSFQKVLELEGEKGEWGFKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYISTSKQNSDFLCQMDLLQEFYETTLEALKDAKNDRLWFKTNTKLGKLYLEREEYGKLQKILRQLHQSCQTDDGEDDLKKECGGKMHLREGEFEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGINPFDSQEAKPYKNDPEILAMTNLVSAYQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRNIRTQVLIKLIKPYTRIHIPFISKELNIDVADVESLLVQCILDNTIHGRIDQVNQLLELDHQKRGGARYTALDKWTNQLNSLNQAVVSKLA

Target ORF information:

RefSeq Version	XM_008762146.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus COP9 signalosome subunit 2 (Cops2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008762146.2

ORF Insert Sequence:

ATGTCTGACA TGGAGGATGA TTTCATGTGC GATGATGAGG AGGACTACGA CCTGGAATAC 
TCTGAAGACA GTAACTCTGA GCCCAACGTG GATTTGGAAA ATCAGTACTA TAATTCCAAA 
GCACTGAAAG AAGATGACCC GAAAGCAGCA CTAAGCAGCT TCCAAAAGGT TTTGGAACTC 
GAAGGTGAGA AGGGAGAATG GGGATTCAAA GCGCTAAAAC AGATGATCAA GATTAACTTC 
AAGCTGACAA ACTTTCCAGA AATGATGAAC AGATATAAGC AACTATTGAC CTATATTCGG 
AGTGCAGTCA CCAGGAACTA CTCTGAAAAG TCTATTAACT CTATCCTTGA CTATATCTCC 
ACTTCTAAAC AGAATTCTGA TTTTTTATGT CAGATGGATT TACTGCAGGA ATTTTATGAA 
ACAACACTGG AAGCTTTGAA AGATGCTAAG AATGATAGAC TGTGGTTTAA GACAAACACA 
AAGCTTGGAA AATTATATTT AGAACGAGAA GAATATGGAA AGCTTCAAAA AATTTTACGC 
CAGTTACATC AGTCTTGTCA GACTGATGAT GGAGAAGATG ACCTGAAAAA AGAATGTGGT 
GGTAAGATGC ACTTGAGAGA AGGTGAATTT GAAAAGGCAC ACACTGATTT TTTTGAAGCT 
TTCAAGAATT ATGATGAATC AGGAAGCCCA AGACGAACCA CTTGTTTAAA ATATTTGGTC 
TTAGCAAATA TGCTAATGAA ATCAGGAATA AATCCATTTG ACTCGCAAGA GGCCAAGCCG 
TATAAAAATG ATCCAGAAAT TCTAGCAATG ACAAATTTAG TAAGTGCCTA TCAGAACAAT 
GACATCACCG AGTTTGAAAA GATTCTGAAA ACAAATCACA GCAACATCAT GGATGATCCT 
TTCATAAGAG AACACATTGA AGAGCTTTTA CGAAACATCA GAACACAAGT CCTCATAAAG 
TTAATTAAGC CTTACACAAG AATACATATT CCTTTTATTT CTAAGGAGCT AAACATAGAC 
GTAGCTGATG TGGAAAGCTT GCTGGTGCAG TGCATACTGG ATAACACTAT TCATGGCCGA 
ATTGATCAAG TCAACCAGCT CCTTGAACTG GATCATCAGA AGAGGGGCGG TGCCCGATAT 
ACTGCACTAG ATAAATGGAC CAACCAACTA AACTCTCTGA ACCAGGCTGT GGTCAGTAAA 
CTGGCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cops2 ( NM_153297.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_695209.1 Rattus norvegicus COP9 signalosome subunit 2 (Cops2), mRNA.

Price & Availability↑

CloneID	ORa02944
Clone ID Related Accession (Same CDS sequence)	NM_153297.1
Accession Version	NM_153297.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1332bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Rattus norvegicus(Norway rat)
Product	COP9 signalosome complex subunit 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB081072.1. ##Evidence-Data-START## Transcript exon combination :: AB081072.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGTCTGACA TGGAGGATGA TTTCATGTGC GATGATGAGG AGGACTACGA CCTGGAATAC 
TCTGAAGACA GTAACTCTGA GCCCAACGTG GATTTGGAAA ATCAGTACTA TAATTCCAAA 
GCACTGAAAG AAGATGACCC GAAAGCAGCA CTAAGCAGCT TCCAAAAGGT TTTGGAACTC 
GAAGGTGAGA AGGGAGAATG GGGATTCAAA GCGCTAAAAC AGATGATCAA GATTAACTTC 
AAGCTGACAA ACTTTCCAGA AATGATGAAC AGATATAAGC AACTATTGAC CTATATTCGG 
AGTGCAGTCA CCAGGAACTA CTCTGAAAAG TCTATTAACT CTATCCTTGA CTATATCTCC 
ACTTCTAAAC AGATGGATTT ACTGCAGGAA TTTTATGAAA CAACACTGGA AGCTTTGAAA 
GATGCTAAGA ATGATAGACT GTGGTTTAAG ACAAACACAA AGCTTGGAAA ATTATATTTA 
GAACGAGAAG AATATGGAAA GCTTCAAAAA ATTTTACGCC AGTTACATCA GTCTTGTCAG 
ACTGATGATG GAGAAGATGA CCTGAAAAAA GGTACCCAGT TATTAGAAAT CTATGCTTTG 
GAAATTCAAA TGTACACGGC ACAGAAGAAC AACAAAAAGC TTAAAGCGCT CTATGAGCAA 
TCACTTCATA TCAAGTCTGC CATCCCTCAC CCACTGATCA TGGGTGTCAT CAGAGAATGT 
GGTGGTAAGA TGCACTTGAG AGAAGGTGAA TTTGAAAAGG CACACACTGA TTTTTTTGAA 
GCTTTCAAGA ATTATGATGA ATCAGGAAGC CCAAGACGAA CCACTTGTTT AAAATATTTG 
GTCTTAGCAA ATATGCTAAT GAAATCAGGA ATAAATCCAT TTGACTCGCA AGAGGCCAAG 
CCGTATAAAA ATGATCCAGA AATTCTAGCA ATGACAAATT TAGTAAGTGC CTATCAGAAC 
AATGACATCA CCGAGTTTGA AAAGATTCTG AAAACAAATC ACAGCAACAT CATGGATGAT 
CCTTTCATAA GAGAACACAT TGAAGAGCTT TTACGAAACA TCAGAACACA AGTCCTCATA 
AAGTTAATTA AGCCTTACAC AAGAATACAT ATTCCTTTTA TTTCTAAGGA GCTAAACATA 
GACGTAGCTG ATGTGGAAAG CTTGCTGGTG CAGTGCATAC TGGATAACAC TATTCATGGC 
CGAATTGATC AAGTCAACCA GCTCCTTGAA CTGGATCATC AGAAGAGGGG CGGTGCCCGA 
TATACTGCAC TAGATAAATG GACCAACCAA CTAAACTCTC TGAACCAGGC TGTGGTCAGT 
AAACTGGCTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_695209.1
CDS	151..1482
Translation	MSDMEDDFMCDDEEDYDLEYSEDSNSEPNVDLENQYYNSKALKEDDPKAALSSFQKVLELEGEKGEWGFKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYISTSKQMDLLQEFYETTLEALKDAKNDRLWFKTNTKLGKLYLEREEYGKLQKILRQLHQSCQTDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPLIMGVIRECGGKMHLREGEFEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGINPFDSQEAKPYKNDPEILAMTNLVSAYQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRNIRTQVLIKLIKPYTRIHIPFISKELNIDVADVESLLVQCILDNTIHGRIDQVNQLLELDHQKRGGARYTALDKWTNQLNSLNQAVVSKLA

Target ORF information:

RefSeq Version	NM_153297.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus COP9 signalosome subunit 2 (Cops2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_153297.1

ORF Insert Sequence:

ATGTCTGACA TGGAGGATGA TTTCATGTGC GATGATGAGG AGGACTACGA CCTGGAATAC 
TCTGAAGACA GTAACTCTGA GCCCAACGTG GATTTGGAAA ATCAGTACTA TAATTCCAAA 
GCACTGAAAG AAGATGACCC GAAAGCAGCA CTAAGCAGCT TCCAAAAGGT TTTGGAACTC 
GAAGGTGAGA AGGGAGAATG GGGATTCAAA GCGCTAAAAC AGATGATCAA GATTAACTTC 
AAGCTGACAA ACTTTCCAGA AATGATGAAC AGATATAAGC AACTATTGAC CTATATTCGG 
AGTGCAGTCA CCAGGAACTA CTCTGAAAAG TCTATTAACT CTATCCTTGA CTATATCTCC 
ACTTCTAAAC AGATGGATTT ACTGCAGGAA TTTTATGAAA CAACACTGGA AGCTTTGAAA 
GATGCTAAGA ATGATAGACT GTGGTTTAAG ACAAACACAA AGCTTGGAAA ATTATATTTA 
GAACGAGAAG AATATGGAAA GCTTCAAAAA ATTTTACGCC AGTTACATCA GTCTTGTCAG 
ACTGATGATG GAGAAGATGA CCTGAAAAAA GGTACCCAGT TATTAGAAAT CTATGCTTTG 
GAAATTCAAA TGTACACGGC ACAGAAGAAC AACAAAAAGC TTAAAGCGCT CTATGAGCAA 
TCACTTCATA TCAAGTCTGC CATCCCTCAC CCACTGATCA TGGGTGTCAT CAGAGAATGT 
GGTGGTAAGA TGCACTTGAG AGAAGGTGAA TTTGAAAAGG CACACACTGA TTTTTTTGAA 
GCTTTCAAGA ATTATGATGA ATCAGGAAGC CCAAGACGAA CCACTTGTTT AAAATATTTG 
GTCTTAGCAA ATATGCTAAT GAAATCAGGA ATAAATCCAT TTGACTCGCA AGAGGCCAAG 
CCGTATAAAA ATGATCCAGA AATTCTAGCA ATGACAAATT TAGTAAGTGC CTATCAGAAC 
AATGACATCA CCGAGTTTGA AAAGATTCTG AAAACAAATC ACAGCAACAT CATGGATGAT 
CCTTTCATAA GAGAACACAT TGAAGAGCTT TTACGAAACA TCAGAACACA AGTCCTCATA 
AAGTTAATTA AGCCTTACAC AAGAATACAT ATTCCTTTTA TTTCTAAGGA GCTAAACATA 
GACGTAGCTG ATGTGGAAAG CTTGCTGGTG CAGTGCATAC TGGATAACAC TATTCATGGC 
CGAATTGATC AAGTCAACCA GCTCCTTGAA CTGGATCATC AGAAGAGGGG CGGTGCCCGA 
TATACTGCAC TAGATAAATG GACCAACCAA CTAAACTCTC TGAACCAGGC TGTGGTCAGT 
AAACTGGCTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cops2 ( XM_006234901.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006234963.1 Rattus norvegicus COP9 signalosome subunit 2 (Cops2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa26306
Clone ID Related Accession (Same CDS sequence)	XM_006234901.3
Accession Version	XM_006234901.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1353bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	COP9 signalosome complex subunit 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006234901.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCTGACA TGGAGGATGA TTTCATGTGC GATGATGAGG AGGACTACGA CCTGGAATAC 
TCTGAAGACA GTAACTCTGA GCCCAACGTG GATTTGGAAA ATCAGTACTA TAATTCCAAA 
GCACTGAAAG AAGATGACCC GAAAGCAGCA CTAAGCAGCT TCCAAAAGGT TTTGGAACTC 
GAAGGTGAGA AGGGAGAATG GGGATTCAAA GCGCTAAAAC AGATGATCAA GATTAACTTC 
AAGCTGACAA ACTTTCCAGA AATGATGAAC AGATATAAGC AACTATTGAC CTATATTCGG 
AGTGCAGTCA CCAGGAACTA CTCTGAAAAG TCTATTAACT CTATCCTTGA CTATATCTCC 
ACTTCTAAAC AGAATTCTGA TTTTTTATGT CAGATGGATT TACTGCAGGA ATTTTATGAA 
ACAACACTGG AAGCTTTGAA AGATGCTAAG AATGATAGAC TGTGGTTTAA GACAAACACA 
AAGCTTGGAA AATTATATTT AGAACGAGAA GAATATGGAA AGCTTCAAAA AATTTTACGC 
CAGTTACATC AGTCTTGTCA GACTGATGAT GGAGAAGATG ACCTGAAAAA AGGTACCCAG 
TTATTAGAAA TCTATGCTTT GGAAATTCAA ATGTACACGG CACAGAAGAA CAACAAAAAG 
CTTAAAGCGC TCTATGAGCA ATCACTTCAT ATCAAGTCTG CCATCCCTCA CCCACTGATC 
ATGGGTGTCA TCAGAGAATG TGGTGGTAAG ATGCACTTGA GAGAAGGTGA ATTTGAAAAG 
GCACACACTG ATTTTTTTGA AGCTTTCAAG AATTATGATG AATCAGGAAG CCCAAGACGA 
ACCACTTGTT TAAAATATTT GGTCTTAGCA AATATGCTAA TGAAATCAGG AATAAATCCA 
TTTGACTCGC AAGAGGCCAA GCCGTATAAA AATGATCCAG AAATTCTAGC AATGACAAAT 
TTAGTAAGTG CCTATCAGAA CAATGACATC ACCGAGTTTG AAAAGATTCT GAAAACAAAT 
CACAGCAACA TCATGGATGA TCCTTTCATA AGAGAACACA TTGAAGAGCT TTTACGAAAC 
ATCAGAACAC AAGTCCTCAT AAAGTTAATT AAGCCTTACA CAAGAATACA TATTCCTTTT 
ATTTCTAAGG AGCTAAACAT AGACGTAGCT GATGTGGAAA GCTTGCTGGT GCAGTGCATA 
CTGGATAACA CTATTCATGG CCGAATTGAT CAAGTCAACC AGCTCCTTGA ACTGGATCAT 
CAGAAGAGGG GCGGTGCCCG ATATACTGCA CTAGATAAAT GGACCAACCA ACTAAACTCT 
CTGAACCAGG CTGTGGTCAG TAAACTGGCT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006234963.1
CDS	89..1441
Translation	MSDMEDDFMCDDEEDYDLEYSEDSNSEPNVDLENQYYNSKALKEDDPKAALSSFQKVLELEGEKGEWGFKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYISTSKQNSDFLCQMDLLQEFYETTLEALKDAKNDRLWFKTNTKLGKLYLEREEYGKLQKILRQLHQSCQTDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPLIMGVIRECGGKMHLREGEFEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGINPFDSQEAKPYKNDPEILAMTNLVSAYQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRNIRTQVLIKLIKPYTRIHIPFISKELNIDVADVESLLVQCILDNTIHGRIDQVNQLLELDHQKRGGARYTALDKWTNQLNSLNQAVVSKLA

Target ORF information:

RefSeq Version	XM_006234901.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus COP9 signalosome subunit 2 (Cops2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006234901.3

ORF Insert Sequence:

ATGTCTGACA TGGAGGATGA TTTCATGTGC GATGATGAGG AGGACTACGA CCTGGAATAC 
TCTGAAGACA GTAACTCTGA GCCCAACGTG GATTTGGAAA ATCAGTACTA TAATTCCAAA 
GCACTGAAAG AAGATGACCC GAAAGCAGCA CTAAGCAGCT TCCAAAAGGT TTTGGAACTC 
GAAGGTGAGA AGGGAGAATG GGGATTCAAA GCGCTAAAAC AGATGATCAA GATTAACTTC 
AAGCTGACAA ACTTTCCAGA AATGATGAAC AGATATAAGC AACTATTGAC CTATATTCGG 
AGTGCAGTCA CCAGGAACTA CTCTGAAAAG TCTATTAACT CTATCCTTGA CTATATCTCC 
ACTTCTAAAC AGAATTCTGA TTTTTTATGT CAGATGGATT TACTGCAGGA ATTTTATGAA 
ACAACACTGG AAGCTTTGAA AGATGCTAAG AATGATAGAC TGTGGTTTAA GACAAACACA 
AAGCTTGGAA AATTATATTT AGAACGAGAA GAATATGGAA AGCTTCAAAA AATTTTACGC 
CAGTTACATC AGTCTTGTCA GACTGATGAT GGAGAAGATG ACCTGAAAAA AGGTACCCAG 
TTATTAGAAA TCTATGCTTT GGAAATTCAA ATGTACACGG CACAGAAGAA CAACAAAAAG 
CTTAAAGCGC TCTATGAGCA ATCACTTCAT ATCAAGTCTG CCATCCCTCA CCCACTGATC 
ATGGGTGTCA TCAGAGAATG TGGTGGTAAG ATGCACTTGA GAGAAGGTGA ATTTGAAAAG 
GCACACACTG ATTTTTTTGA AGCTTTCAAG AATTATGATG AATCAGGAAG CCCAAGACGA 
ACCACTTGTT TAAAATATTT GGTCTTAGCA AATATGCTAA TGAAATCAGG AATAAATCCA 
TTTGACTCGC AAGAGGCCAA GCCGTATAAA AATGATCCAG AAATTCTAGC AATGACAAAT 
TTAGTAAGTG CCTATCAGAA CAATGACATC ACCGAGTTTG AAAAGATTCT GAAAACAAAT 
CACAGCAACA TCATGGATGA TCCTTTCATA AGAGAACACA TTGAAGAGCT TTTACGAAAC 
ATCAGAACAC AAGTCCTCAT AAAGTTAATT AAGCCTTACA CAAGAATACA TATTCCTTTT 
ATTTCTAAGG AGCTAAACAT AGACGTAGCT GATGTGGAAA GCTTGCTGGT GCAGTGCATA 
CTGGATAACA CTATTCATGG CCGAATTGAT CAAGTCAACC AGCTCCTTGA ACTGGATCAT 
CAGAAGAGGG GCGGTGCCCG ATATACTGCA CTAGATAAAT GGACCAACCA ACTAAACTCT 
CTGAACCAGG CTGTGGTCAG TAAACTGGCT TAA