Cebpd cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cebpd
Entrez Gene ID	25695
Full Name	CCAAT/enhancer binding protein delta
Synonyms	C/EBPd,CELF
General protein information	Preferred Names CCAAT/enhancer binding protein delta Names CCAAT/enhancer-binding protein delta C/EBP-delta C/EBPdelta CCAAT/enhancer binding protein (C/EBP), delta c/EBP delta transcription factor CELF
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 11 Map Location: 11q23
Summary	transcriptional activator; activity is stimulated by sepsis, keratinocyte growth factor, and may be involved in glucose-mediated regulation of iNOS [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_013154.2	NP_037286.1	CCAAT/enhancer-binding protein delta

Pathways from BioSystems

Homologies

Homo sapiens (human)	CEBPD	NP_005186.2
Rattus norvegicus (Norway rat)	Cebpd	NP_037286.1
Pan troglodytes (chimpanzee)	CEBPD	XP_003951307.1
Danio rerio (zebrafish)	cebpd	NP_571962.1
Mus musculus (house mouse)	Cebpd	NP_031705.3
Xenopus tropicalis (tropical clawed frog)	cebpd	NP_001025585.1
Canis lupus familiaris (dog)	CEBPD	XP_848281.1
Bos taurus (cattle)	CEBPD	NP_776692.2

Gene Ontology
Bibliography

Related articles in PubMed

Androgen receptor activation integrates complex transcriptional effects in osteoblasts, involving the growth factors TGF-? and IGF-I, and transcription factor C/EBP?.
McCarthy TL, Centrella M
Gene573(1)129-40(2015 Nov)

Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7.
Nagamachi A, Matsui H, Asou H, Ozaki Y, Aki D, Kanai A, Takubo K, Suda T, Nakamura T, Wolff L, Honda H, Inaba T
Cancer cell24(3)305-17(2013 Sep)

CCAAT enhancer binding protein ? plays an essential role in memory consolidation and reconsolidation.
Arguello AA, Ye X, Bozdagi O, Pollonini G, Tronel S, Bambah-Mukku D, Huntley GW, Platano D, Alberini CM
The Journal of neuroscience : the official journal of the Society for Neuroscience33(8)3646-58(2013 Feb)

The transcription factor C/EBP delta has anti-apoptotic and anti-inflammatory roles in pancreatic beta cells.
Moore F, Santin I, Nogueira TC, Gurzov EN, Marselli L, Marchetti P, Eizirik DL
PloS one7(2)e31062(2012)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

DHT activated AR inhibits gene transactivation by C/EBPdelta, and transgenic C/EBPdelta expression inhibits AR activity
Title: Androgen receptor activation integrates complex transcriptional effects in osteoblasts, involving the growth factors TGF-? and IGF-I, and transcription factor C/EBP?.

C/EBPdelta plays a critical role in both memory consolidation and reconsolidation.
Title: CCAAT enhancer binding protein ? plays an essential role in memory consolidation and reconsolidation.

novel function of C/EBPdelta as a modulatory transcription factor that inhibits the pro-apoptotic and pro-inflammatory gene networks activated by cytokines in pancreatic beta-cells.
Title: The transcription factor C/EBP delta has anti-apoptotic and anti-inflammatory roles in pancreatic beta cells.

The results show that PRL expression and cell proliferation are controlled in part by CEBPD.
Title: CEBPD suppresses prolactin expression and prolactinoma cell proliferation.

These data suggest that both expression and function of C/EBPdelta are dysregulated in Alzheimer's disease.
Title: The CCAAT/enhancer binding protein (C/EBP) ? is differently regulated by fibrillar and oligomeric forms of the Alzheimer amyloid-? peptide.

The following Cebpd gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cebpd cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa42523	NM_013154.2 Latest version!	Rattus norvegicus CCAAT/enhancer binding protein delta (Cebpd), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cebpd ( NM_013154.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_037286.1 Rattus norvegicus CCAAT/enhancer binding protein delta (Cebpd), mRNA.

Price & Availability↑

CloneID	ORa42523
Clone ID Related Accession (Same CDS sequence)	NM_013154.2
Accession Version	NM_013154.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 807bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Rattus norvegicus(Norway rat)
Product	CCAAT/enhancer-binding protein delta
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AAHX01070471.1 and M65149.1. On Feb 13, 2007 this sequence version replaced NM_013154.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.

ATGAGCGCCG CTCTTTTCAG CCTAGACAGC CCAGCACGCG GCGCACCCTG GCCCACAGAG 
CCCGCGGCCT TCTACGAGCC AGGCAGGGTG GGCAAGCCAG GACGAGGGCC GGAGCCTGGG 
GATCTGGGGG AGCCGGGCTC CACGACCCCT GCCATGTATG ACGACGAGAG CGCCATCGAC 
TTCAGCGCCT ACATTGATTC CATGGCTGCC GTGCCCACCC TAGAGTTGTG CCACGACGAG 
ATCTTCGCCG ACCTCTTCAA CAGCAATCAC AAAGCGGCCG GCGCGGGCAG CCTGGAGCTG 
CTGCAGGGCG GCCCTACGCG ACCCCCGGGT GTGGGGTCAA TCGCCAGGGG CCCGCTGAAG 
CGCGAACCCG ACTGGGGCGA CGGCGACGCG CCGGGCTCCC TGCTGCCGGC GCAAGTGGCA 
GTGTGCGCGC AGACAGTGGT GAGCTTGGCG GCCGCGGCAC AGCCCACACC ACCCACTTCG 
CCCGAGCCTC CTCGAGGCAG CCCTGGACCG AGCCTTGCGC CTGGCCCCGT CCGAGAGAAG 
GGCGCCGGCA AGAGGGGTCC GGACCGGGGC AGCCCTGAGT ACCGGCAGCG ACGCGAGCGC 
AACAACATCG CTGTGCGCAA GAGCCGGGAC AAGGCCAAGC GCCGCAACCA GGAGATGCAG 
CAGAAGCTGG TGGAGCTGTC GGCCGAGAAC GAGAAGCTGC ATCAGCGTGT GGAGCAGCTC 
ACCCGGGACC TGGCCAGCCT CCGGCAGTTC TTCAAAGAGC TGCCCAGCCC GCCTTTCCTG 
CCGCCCACCG GCACCGACTG CCGGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_037286.1
CDS	33..839
Translation	MSAALFSLDSPARGAPWPTEPAAFYEPGRVGKPGRGPEPGDLGEPGSTTPAMYDDESAIDFSAYIDSMAAVPTLELCHDEIFADLFNSNHKAAGAGSLELLQGGPTRPPGVGSIARGPLKREPDWGDGDAPGSLLPAQVAVCAQTVVSLAAAAQPTPPTSPEPPRGSPGPSLAPGPVREKGAGKRGPDRGSPEYRQRRERNNIAVRKSRDKAKRRNQEMQQKLVELSAENEKLHQRVEQLTRDLASLRQFFKELPSPPFLPPTGTDCR

Target ORF information:

RefSeq Version	NM_013154.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus CCAAT/enhancer binding protein delta (Cebpd), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_013154.2

ORF Insert Sequence:

ATGAGCGCCG CTCTTTTCAG CCTAGACAGC CCAGCACGCG GCGCACCCTG GCCCACAGAG 
CCCGCGGCCT TCTACGAGCC AGGCAGGGTG GGCAAGCCAG GACGAGGGCC GGAGCCTGGG 
GATCTGGGGG AGCCGGGCTC CACGACCCCT GCCATGTATG ACGACGAGAG CGCCATCGAC 
TTCAGCGCCT ACATTGATTC CATGGCTGCC GTGCCCACCC TAGAGTTGTG CCACGACGAG 
ATCTTCGCCG ACCTCTTCAA CAGCAATCAC AAAGCGGCCG GCGCGGGCAG CCTGGAGCTG 
CTGCAGGGCG GCCCTACGCG ACCCCCGGGT GTGGGGTCAA TCGCCAGGGG CCCGCTGAAG 
CGCGAACCCG ACTGGGGCGA CGGCGACGCG CCGGGCTCCC TGCTGCCGGC GCAAGTGGCA 
GTGTGCGCGC AGACAGTGGT GAGCTTGGCG GCCGCGGCAC AGCCCACACC ACCCACTTCG 
CCCGAGCCTC CTCGAGGCAG CCCTGGACCG AGCCTTGCGC CTGGCCCCGT CCGAGAGAAG 
GGCGCCGGCA AGAGGGGTCC GGACCGGGGC AGCCCTGAGT ACCGGCAGCG ACGCGAGCGC 
AACAACATCG CTGTGCGCAA GAGCCGGGAC AAGGCCAAGC GCCGCAACCA GGAGATGCAG 
CAGAAGCTGG TGGAGCTGTC GGCCGAGAAC GAGAAGCTGC ATCAGCGTGT GGAGCAGCTC 
ACCCGGGACC TGGCCAGCCT CCGGCAGTTC TTCAAAGAGC TGCCCAGCCC GCCTTTCCTG 
CCGCCCACCG GCACCGACTG CCGGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Androgen receptor activation integrates complex transcriptional effects in osteoblasts, involving the growth factors TGF-? and IGF-I, and transcription factor C/EBP?.
Gene573(1)129-40(2015 Nov)
McCarthy TL,Centrella M

Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7.
Cancer cell24(3)305-17(2013 Sep)
Nagamachi A,Matsui H,Asou H,Ozaki Y,Aki D,Kanai A,Takubo K,Suda T,Nakamura T,Wolff L,Honda H,Inaba T

CCAAT enhancer binding protein ? plays an essential role in memory consolidation and reconsolidation.
The Journal of neuroscience : the official journal of the Society for Neuroscience33(8)3646-58(2013 Feb)
Arguello AA,Ye X,Bozdagi O,Pollonini G,Tronel S,Bambah-Mukku D,Huntley GW,Platano D,Alberini CM

The transcription factor C/EBP delta has anti-apoptotic and anti-inflammatory roles in pancreatic beta cells.
PloS one7(2)e31062(2012)
Moore F,Santin I,Nogueira TC,Gurzov EN,Marselli L,Marchetti P,Eizirik DL

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Cebpd cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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