Ptprs cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ptprs
Entrez Gene ID	25529
Full Name	protein tyrosine phosphatase, receptor type, S
Synonyms	Larptp2,Ptprd,Ptpsigma,Ptpsigma.,Rptpd
General protein information	Preferred Names protein tyrosine phosphatase, receptor type, S Names receptor-type tyrosine-protein phosphatase S LAR-PTP2 R-PTP-S R-PTP-sigma leukocyte common antigen-related protein-tyrosine phosphatase 2 leukocyte common antigen-related proten-tyrosine phosphatase 2 protein tyrosine phosphatase, receptor type, D receptor-type tyrosine-protein phosphatase sigma
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 9 Map Location: 9q12
Summary	has protein tyrosine phosphatase activity; may regulate receptor tyrosine kinases [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_019140.2	NP_062013.1	receptor-type tyrosine-protein phosphatase S precursor

Pathways from BioSystems

Homologies

Bos taurus (cattle)	PTPRS	XP_002688964.1
Rattus norvegicus (Norway rat)	Ptprs	NP_062013.1
Danio rerio (zebrafish)	ptprsa	XP_001920953.4
Homo sapiens (human)	PTPRS	NP_002841.3
Pan troglodytes (chimpanzee)	PTPRS	XP_003316070.1
	PTPRS	XP_001083499.2
Mus musculus (house mouse)	Ptprs	NP_035348.2

Gene Ontology
Bibliography

Related articles in PubMed

Aberrant astrocytic expression of chondroitin sulfate proteoglycan receptors in a rat model of amyotrophic lateral sclerosis.
Shijo T, Warita H, Suzuki N, Kitajima Y, Ikeda K, Akiyama T, Ono H, Mitsuzawa S, Nishiyama A, Izumi R, Aoki M
Journal of neuroscience research96(2)222-233(2018 Feb)

SALM5 trans-synaptically interacts with LAR-RPTPs in a splicing-dependent manner to regulate synapse development.
Choi Y, Nam J, Whitcomb DJ, Song YS, Kim D, Jeon S, Um JW, Lee SG, Woo J, Kwon SK, Li Y, Mah W, Kim HM, Ko J, Cho K, Kim E
Scientific reports626676(2016 May)

Enhanced regeneration and functional recovery after spinal root avulsion by manipulation of the proteoglycan receptor PTP?.
Li H, Wong C, Li W, Ruven C, He L, Wu X, Lang BT, Silver J, Wu W
Scientific reports514923(2015 Oct)

Protein Tyrosine Phosphatase PTPRS Is an Inhibitory Receptor on Human and Murine Plasmacytoid Dendritic Cells.
Bunin A, Sisirak V, Ghosh HS, Grajkowska LT, Hou ZE, Miron M, Yang C, Ceribelli M, Uetani N, Chaperot L, Plumas J, Hendriks W, Tremblay ML, H?cker H, Staudt LM, Green PH, Bhagat G, Reizis B
Immunity43(2)277-88(2015 Aug)

PTP? functions as a presynaptic receptor for the glypican-4/LRRTM4 complex and is essential for excitatory synaptic transmission.
Ko JS, Pramanik G, Um JW, Shim JS, Lee D, Kim KH, Chung GY, Condomitti G, Kim HM, Kim H, de Wit J, Park KS, Tabuchi K, Ko J
Proceedings of the National Academy of Sciences of the United States of America112(6)1874-9(2015 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Our study shows that modulation of PTPsigma is a potential therapeutic strategy for root avulsion.
Title: Enhanced regeneration and functional recovery after spinal root avulsion by manipulation of the proteoglycan receptor PTP?.

results add a new layer of understanding to the critical role of PTPsigma in mediating the growth-inhibited state of neurons due to CSPGs within the injured adult spinal cord
Title: Modulation of the proteoglycan receptor PTP? promotes recovery after spinal cord injury.

PTPsigma functions as a presynaptic receptor for the glypican-4/LRRTM4 complex and is essential for excitatory synaptic transmission.
Title: PTP? functions as a presynaptic receptor for the glypican-4/LRRTM4 complex and is essential for excitatory synaptic transmission.

The changes in the coexpression of perineuronal nets, parvalbumin and PTPsigma provide valuable insights into the connection between chondroitin sulfates and parvalbumin neurons.
Title: Expression of perineuronal nets, parvalbumin and protein tyrosine phosphatase ? in the rat visual cortex during development and after BFD.

Trans-synaptic adhesions between netrin-G ligand-3 (NGL-3) and receptor tyrosine phosphatases LAR, protein-tyrosine phosphatase delta (PTPdelta), and PTPsigma via specific domains regulate excitatory synapse formation.
Title: Trans-synaptic adhesions between netrin-G ligand-3 (NGL-3) and receptor tyrosine phosphatases LAR, protein-tyrosine phosphatase delta (PTPdelta), and PTPsigma via specific domains regulate excitatory synapse formation.

The following Ptprs gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ptprs cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa12685	NM_019140.2 Latest version!	Rattus norvegicus protein tyrosine phosphatase, receptor type, S (Ptprs), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$1644.30 $2349.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ptprs ( NM_019140.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_062013.1 Rattus norvegicus protein tyrosine phosphatase, receptor type, S (Ptprs), mRNA.

Price & Availability↑

CloneID	ORa12685
Clone ID Related Accession (Same CDS sequence)	NM_019140.2
Accession Version	NM_019140.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 5592bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-14
Organism	Rattus norvegicus(Norway rat)
Product	receptor-type tyrosine-protein phosphatase S precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from L11587.1. On Jan 23, 2004 this sequence version replaced NM_019140.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGCGCCCA CCTGGAGACC CAGCGTGGTG TCTGTGGTGG GTCCTGTGGG GCTCTTCCTT 
GTACTGCTGG CCAGAGGGTG CTTGGCTGAA GAGCCACCCA GATTTATCAG AGAGCCCAAG 
GATCAGATTG GTGTGTCAGG AGGCGTGGCC TCCTTCGTGT GCCAGGCCAC AGGTGACCCT 
AAGCCACGGG TGACCTGGAA CAAGAAGGGC AAGAAAGTGA ACTCACAGCG CTTTGAGACC 
ATTGACTTTG ACGAGAGCTC GGGGGCCGTG CTGAGGATCC AGCCACTTCG GACACCCCGG 
GATGAGAACG TGTACGAGTG TGTGGCCCAG AACTCGGTGG GGGAGATCAC AGTTCATGCG 
AAGCTCACCG TCCTGCGAGA GGACCAGCTG CCTCCTGGCT TCCCCAACAT TGACATGGGC 
CCCCAGTTGA AGGTTGTAGA GCGCACACGC ACAGCCACCA TGCTCTGTGC TGCCAGCGGA 
AACCCTGACC CTGAGATCAC CTGGTTCAAG GACTTCCTGC CTGTGGACCC CAGTGCCAGC 
AATGGGCGGA TCAAGCAGCT TCGGTCAGGT GCCCTGCAGA TTGAGAGCAG CGAGGAGACA 
GACCAGGGCA AGTACGAGTG TGTGGCCACC AACAGCGCTG GGGTGCGCTA CTCATCACCT 
GCCAACCTCT ACGTGCGAGT CCGCCGTGTG GCCCCCCGCT TCTCCATCCT GCCCATGAGC 
CACGAGATCA TGCCCGGTGG GAATGTGAAT ATCACTTGTG TGGCTGTGGG CTCACCCATG 
CCCTACGTGA AGTGGATGCA GGGGGCAGAG GACCTGACGC CTGAGGATGA CATGCCCGTG 
GGTCGGAATG TCCTCGAACT CACGGATGTC AAAGACTCAG CCAACTATAC TTGTGTGGCC 
ATGTCCAGCC TGGGAGTGAT CGAGGCCGTT GCTCAGATCA CTGTAAAATC TCTCCCCAAA 
GCCCCTGGGA CTCCCGTGGT GACGGAGAAC ACTGCTACCA GTATCACTGT CACATGGGAC 
TCAGGCAATC CTGACCCTGT GTCCTACTAC GTAATTGAGT ATAAATCCAA AAGCCAGGAT 
GGGCCGTATC AGATCAAAGA AGACATCACC ACCACGCGCT ACAGCATCGG CGGCCTGAGC 
CCCAACTCTG AGTATGAGAT CTGGGTGTCA GCTGTCAACT CCATCGGCCA GGGCCCCCCC 
AGTGAGTCGG TGGTGACCCG CACAGGCGAG CAGGCACCAG CCAGTGCTCC CAGGAATGTT 
CAGGCGCGCA TGCTCAGTGC CACCACCATG ATTGTGCAGT GGGAGGAGCC CGTGGAGCCC 
AATGGCCTGA TCCGTGGCTA CCGCGTCTAC TACACCATGG AGCCCGAGCA TCCGGTGGGC 
AACTGGCAGA AGCACAATGT GGACGACAGT CTTCTGACCA CTGTGGGCAG CCTGCTAGAG 
GATGAGACCT ACACTGTGAG AGTGCTCGCC TTCACATCGG TGGGCGATGG GCCACTGTCA 
GACCCCATCC AGGTCAAGAC CCAGCAGGGA GTGCCCGGCC AGCCCATGAA CTTGCGGGCT 
GAGGCCAAGT CAGAGACCAG CATTGGGCTC TCGTGGAGTG CACCACGGCA GGAGAGTGTC 
ATTAAGTATG AACTGCTCTT CCGGGAGGGC GACCGAGGCC GAGAGGTGGG GCGAACCTTC 
GACCCAACCA CAGCCTTTGT GGTGGAGGAC CTCAAGCCCA ATACGGAGTA CGCGTTCCGG 
CTGGCGGCTC GCTCGCCGCA GGGCCTGGGC GCCTTCACCG CGGTTGTGTG CCAGCGCACA 
CTGCAGGCCA AACCGTCAGC CCCCCCTCAA GACGTTAAGT GCACCAGCTT GCGCTCCACG 
GCCATATTGA TCCTTCTGGA AGCTTTGGAG AAATGGACGG AGTACCGTGT CACCGCCGTG 
GCTTACACAG AGGTGGGACC AGGGCCCGAG AGCTCGCCCG TGGTCGTCCG CACCGATGAG 
GACGTGCCCA GCGCGCCCCC GCGGAAGGTG GAGGCGGAGG CGCTCAACGC CACGGCTATC 
CGAGTGCTGT GGCGCTCGCC CACGCCCGGC AGGCAGCACG GGCAGATCCG CGGCTACCAG 
GTCCACTATG TGCGCATGGA GGGCACCGAG GCCCGCGGGC CACCGCGCAT CAAGGACATC 
ATGCTGGCGG ATGCCCAGGA AATGGTGATC ACAAACCTCC AGCCTGAGAC TGCTTACTCT 
ATCACAGTAG CCGCGTATAC CATGAAAGGC GATGGCGCTC GCAGCAAACC GAAGGTGGTG 
GTGACCAAGG GAGCAGTGCT GGGCCGCCCC ACCCTGTCGG TGCAGCAGAC CCCCGAGGGC 
AGCCTGCTGG CGCGCTGGGA GCCCCCCGCG GACGCGGCTG AGGACCCAGT GCTTGGCTAC 
CGCCTGCAGT TTGGGCGCGA AGACGCGGCC CCGGCCACGT TGGAACTGGC GGCGTGGGAG 
CGGCGGTTCG CGGCGCCTGC ACACAAGGGC GCCACCTATG TGTTTCGGCT GGCGGCGCGG 
GGCCGCGCGG GGCTGGGCGA GGAGGCCTCG GCGGCGCTGA GCATCCCTGA GGACGCTCCG 
CGTGGCTTCC CGCAGATCCT GGGCCCCGCG GGCAACGTGT CCGCGGGCTC CGTAATACTG 
CGCTGGCTGC CACCCGTGCC CGCCGAGGGC AACGGCGCCA TCATCAAGTA CACGGTGTCC 
GTGCGGGAGG CCGGCACCCC AGGGCCCGCG ACAGAGACCG AACTGGCGGC GGCGGCCCAG 
CCGGGGGCCG AGACAGCGCT CACACTACAG GGGCTGCGGC CGGAGACGGC CTACGAGCTG 
CGCGTGCGCG CGCACACGCG TCGGGGCCCC GGCCCCTTCT CACCCCCGCT GCGATACAGG 
CTTGCGCGGG ACCCAGTCTC CCCCAAGAAC TTCAAGGTGA AGATGATCAT GAAAACTTCA 
GTGCTGCTAA GCTGGGAGTT CCCTGACAAC TATAACTCAC CCACGCCCTA CAAGATCCAG 
TACAATGGAC TCACACTGGA CGTGGATGGC CGCACTACCA AGAAGCTGAT CACGCACCTC 
AAGCCACACA CCTTCTATAA CTTCGTGCTC ACCAACCGTG GCAGCAGCCT GGGAGGCCTG 
CAGCAGACGG TCACCGCCAG GACCGCCTTC AACATGCTCA GTGGCAAGCC TAGTGTCGCC 
CCAAAGCCTG ACAACGATGG TTCCATTGTG GTCTACCTGC CTGATGGCCA GAGTCCCGTG 
ACAGTGCAGA ACTACTTCAT TGTGATGGTC CCACTTCGGA AGTCTCGTGG TGGCCAGTTC 
CCTATCCTAC TAGGTAGTCC AGAGGACATG GATCTGGAGG AGCTCATCCA GGACCTCTCC 
CGGCTGCAGA GGCGCAGCCT GCGCCACTCA AGACAGCTGG AGGTGCCTCG GCCTTACATC 
GCCGCTCGGT TCTCCATCCT GCCAGCTGTC TTCCATCCTG GGAACCAGAA GCAATATGGT 
GGCTTTGACA ACAGGGGCTT GGAGCCAGGC CACCGTTATG TCCTCTTTGT ACTTGCTGTG 
CTGCAGAAGA ATGAGCCTAC ATTTGCAGCC AGTCCCTTCT CAGACCCCTT CCAACTGGAC 
AACCCAGACC CGCAGCCCAT TGTGGATGGC GAGGAGGGCC TCATCTGGGT GATCGGGCCC 
GTGCTGGCCG TGGTCTTCAT CATCTGCATC GTAATTGCCA TCCTGCTGTA CAAGAACAAG 
CCTGACAGCA AACGCAAGGA CTCAGAGCCC CGCACCAAAT GCTTATTGAA CAATGCAGAC 
CTCGCCCCCC ATCACCCCAA GGACCCTGTG GAAATGCGAC GTATCAACTT CCAGACGCCA 
GGTATGCTCA GCCACCCGCC CATTCCCATC ACAGACATGG CTGAACACAT GGAGAGACTC 
AAAGCCAACG ACAGCCTCAA GCTCTCCCAG GAGTATGAGT CCATCGACCC TGGCCAGCAG 
TTCACTTGGG AACATTCGAA CCTGGAGGCC AACAAGCCAA AGAACCGATA CGCCAATGTC 
ATCGCCTATG ACCATTCACG AGTCATCCTG CAGCCTTTAG AAGGCATCAT GGGTAGTGAT 
TACATCAATG CCAACTATGT GGACGGCTAT CGGCGGCAGA ACGCATACAT CGCCACGCAG 
GGGCCCCTGC CTGAGACCTT TGGGGACTTC TGGCGGATGG TGTGGGAGCA GCGGTCAGCC 
ACTGTGGTCA TGATGACACG GCTGGAGGAG AAATCACGGG TCAAATGTGA CCAGTACTGG 
CCTAACCGAG GCACCGAGAC ATACGGCTTC ATCCAGGTCA CCCTACTAGA TACTATGGAG 
CTGGCCACCT TCTGTGTCAG GACCTTTTCT CTACACAAGA ATGGCTCTAG TGAGAAGCGT 
GAGGTACGAC ATTTTCAGTT CACAGCATGG CCTGACCACG GGGTACCCGA GTACCCCACA 
CCCTTCCTGG CGTTTCTGCG CAGAGTCAAG ACCTGCAACC CGCCTGACGC TGGCCCAGTT 
GTGGTCCACT GCAGCGCGGG TGTGGGGCGT ACTGGCTGCT TCATTGTAAT TGATGCCATG 
TTGGAGCGCA TCAGAACAGA GAAGACGGTG GATGTGTACG GACACGTGAC ACTCATGCGG 
TCACAGCGCA ACTACATGGT GCAGACAGAG GATCAGTATA GCTTCATCCA CGAGGCACTG 
CTGGAGGCTG TGGGCTGTGG CAATACCGAG GTCCCCGCGC GCAGCCTCTA CACCTATATC 
CAGAAGCTGG CCCAGGTGGA GCCTGGCGAG CATGTCACAG GAATGGAGCT TGAGTTCAAG 
AGGCTTGCCA GCTCCAAGGC ACACACTTCG AGATTCATCA CTGCCAGCCT GCCTTGCAAC 
AAGTTTAAGA ACCGCCTGGT GAACATCCTG CCGTACGAGA GCTCGCGTGT CTGCCTGCAG 
CCCATTCGTG GTGTCGAGGG CTCTGACTAC ATCAATGCCA GCTTCATCGA CGGCTACAGA 
CAGCAGAAAG CCTACATTGC AACGCAGGGT CCACTGGCAG AGACCACAGA GGACTTCTGG 
CGTGCCCTGT GGGAGAACAA CTCCACTATT GTGGTAATGC TCACCAAGCT CCGCGAGATG 
GGCCGGGAGA AGTGCCACCA GTACTGGCCA GCTGAACGCT CTGCCCGCTA CCAGTACTTT 
GTGGTTGACC CGATGGCAGA GTATAACATG CCACAGTACA TTCTGCGTGA GTTTAAGGTC 
ACAGATGCCC GGGATGGCCA GTCCCGGACC GTCCGACAGT TCCAGTTCAC GGACTGGCCA 
GAGCAGGGTG CACCCAAGTC AGGGGAAGGC TTCATTGACT TCATCGGCCA AGTGCATAAG 
ACCAAGGAGC AGTTTGGCCA GGATGGCCCC ATCTCGGTGC ACTGTAGTGC TGGAGTGGGC 
AGGACCGGAG TATTCATCAC TCTGAGCATC GTGCTGGAGC GAATGCGCTA CGAGGGGGTG 
GTGGACATTT TCCAGACAGT GAAGGTGCTT CGGACCCAGC GGCCTGCCAT GGTGCAGACA 
GAGGATGAGT ACCAGTTCTG CTTCCAGGCG GCGTTGGAAT ACCTGGGCAG CTTTGATCAT 
TATGCAACAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_062013.1
CDS	185..5776
Translation	MAPTWRPSVVSVVGPVGLFLVLLARGCLAEEPPRFIREPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIDFDESSGAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPPGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVATNSAGVRYSSPANLYVRVRRVAPRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTPEDDMPVGRNVLELTDVKDSANYTCVAMSSLGVIEAVAQITVKSLPKAPGTPVVTENTATSITVTWDSGNPDPVSYYVIEYKSKSQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEAKSETSIGLSWSAPRQESVIKYELLFREGDRGREVGRTFDPTTAFVVEDLKPNTEYAFRLAARSPQGLGAFTAVVCQRTLQAKPSAPPQDVKCTSLRSTAILILLEALEKWTEYRVTAVAYTEVGPGPESSPVVVRTDEDVPSAPPRKVEAEALNATAIRVLWRSPTPGRQHGQIRGYQVHYVRMEGTEARGPPRIKDIMLADAQEMVITNLQPETAYSITVAAYTMKGDGARSKPKVVVTKGAVLGRPTLSVQQTPEGSLLARWEPPADAAEDPVLGYRLQFGREDAAPATLELAAWERRFAAPAHKGATYVFRLAARGRAGLGEEASAALSIPEDAPRGFPQILGPAGNVSAGSVILRWLPPVPAEGNGAIIKYTVSVREAGTPGPATETELAAAAQPGAETALTLQGLRPETAYELRVRAHTRRGPGPFSPPLRYRLARDPVSPKNFKVKMIMKTSVLLSWEFPDNYNSPTPYKIQYNGLTLDVDGRTTKKLITHLKPHTFYNFVLTNRGSSLGGLQQTVTARTAFNMLSGKPSVAPKPDNDGSIVVYLPDGQSPVTVQNYFIVMVPLRKSRGGQFPILLGSPEDMDLEELIQDLSRLQRRSLRHSRQLEVPRPYIAARFSILPAVFHPGNQKQYGGFDNRGLEPGHRYVLFVLAVLQKNEPTFAASPFSDPFQLDNPDPQPIVDGEEGLIWVIGPVLAVVFIICIVIAILLYKNKPDSKRKDSEPRTKCLLNNADLAPHHPKDPVEMRRINFQTPGMLSHPPIPITDMAEHMERLKANDSLKLSQEYESIDPGQQFTWEHSNLEANKPKNRYANVIAYDHSRVILQPLEGIMGSDYINANYVDGYRRQNAYIATQGPLPETFGDFWRMVWEQRSATVVMMTRLEEKSRVKCDQYWPNRGTETYGFIQVTLLDTMELATFCVRTFSLHKNGSSEKREVRHFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPVVVHCSAGVGRTGCFIVIDAMLERIRTEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEALLEAVGCGNTEVPARSLYTYIQKLAQVEPGEHVTGMELEFKRLASSKAHTSRFITASLPCNKFKNRLVNILPYESSRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRALWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGAPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKVLRTQRPAMVQTEDEYQFCFQAALEYLGSFDHYAT

Target ORF information:

RefSeq Version	NM_019140.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus protein tyrosine phosphatase, receptor type, S (Ptprs), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019140.2

ORF Insert Sequence:

ATGGCGCCCA CCTGGAGACC CAGCGTGGTG TCTGTGGTGG GTCCTGTGGG GCTCTTCCTT 
GTACTGCTGG CCAGAGGGTG CTTGGCTGAA GAGCCACCCA GATTTATCAG AGAGCCCAAG 
GATCAGATTG GTGTGTCAGG AGGCGTGGCC TCCTTCGTGT GCCAGGCCAC AGGTGACCCT 
AAGCCACGGG TGACCTGGAA CAAGAAGGGC AAGAAAGTGA ACTCACAGCG CTTTGAGACC 
ATTGACTTTG ACGAGAGCTC GGGGGCCGTG CTGAGGATCC AGCCACTTCG GACACCCCGG 
GATGAGAACG TGTACGAGTG TGTGGCCCAG AACTCGGTGG GGGAGATCAC AGTTCATGCG 
AAGCTCACCG TCCTGCGAGA GGACCAGCTG CCTCCTGGCT TCCCCAACAT TGACATGGGC 
CCCCAGTTGA AGGTTGTAGA GCGCACACGC ACAGCCACCA TGCTCTGTGC TGCCAGCGGA 
AACCCTGACC CTGAGATCAC CTGGTTCAAG GACTTCCTGC CTGTGGACCC CAGTGCCAGC 
AATGGGCGGA TCAAGCAGCT TCGGTCAGGT GCCCTGCAGA TTGAGAGCAG CGAGGAGACA 
GACCAGGGCA AGTACGAGTG TGTGGCCACC AACAGCGCTG GGGTGCGCTA CTCATCACCT 
GCCAACCTCT ACGTGCGAGT CCGCCGTGTG GCCCCCCGCT TCTCCATCCT GCCCATGAGC 
CACGAGATCA TGCCCGGTGG GAATGTGAAT ATCACTTGTG TGGCTGTGGG CTCACCCATG 
CCCTACGTGA AGTGGATGCA GGGGGCAGAG GACCTGACGC CTGAGGATGA CATGCCCGTG 
GGTCGGAATG TCCTCGAACT CACGGATGTC AAAGACTCAG CCAACTATAC TTGTGTGGCC 
ATGTCCAGCC TGGGAGTGAT CGAGGCCGTT GCTCAGATCA CTGTAAAATC TCTCCCCAAA 
GCCCCTGGGA CTCCCGTGGT GACGGAGAAC ACTGCTACCA GTATCACTGT CACATGGGAC 
TCAGGCAATC CTGACCCTGT GTCCTACTAC GTAATTGAGT ATAAATCCAA AAGCCAGGAT 
GGGCCGTATC AGATCAAAGA AGACATCACC ACCACGCGCT ACAGCATCGG CGGCCTGAGC 
CCCAACTCTG AGTATGAGAT CTGGGTGTCA GCTGTCAACT CCATCGGCCA GGGCCCCCCC 
AGTGAGTCGG TGGTGACCCG CACAGGCGAG CAGGCACCAG CCAGTGCTCC CAGGAATGTT 
CAGGCGCGCA TGCTCAGTGC CACCACCATG ATTGTGCAGT GGGAGGAGCC CGTGGAGCCC 
AATGGCCTGA TCCGTGGCTA CCGCGTCTAC TACACCATGG AGCCCGAGCA TCCGGTGGGC 
AACTGGCAGA AGCACAATGT GGACGACAGT CTTCTGACCA CTGTGGGCAG CCTGCTAGAG 
GATGAGACCT ACACTGTGAG AGTGCTCGCC TTCACATCGG TGGGCGATGG GCCACTGTCA 
GACCCCATCC AGGTCAAGAC CCAGCAGGGA GTGCCCGGCC AGCCCATGAA CTTGCGGGCT 
GAGGCCAAGT CAGAGACCAG CATTGGGCTC TCGTGGAGTG CACCACGGCA GGAGAGTGTC 
ATTAAGTATG AACTGCTCTT CCGGGAGGGC GACCGAGGCC GAGAGGTGGG GCGAACCTTC 
GACCCAACCA CAGCCTTTGT GGTGGAGGAC CTCAAGCCCA ATACGGAGTA CGCGTTCCGG 
CTGGCGGCTC GCTCGCCGCA GGGCCTGGGC GCCTTCACCG CGGTTGTGTG CCAGCGCACA 
CTGCAGGCCA AACCGTCAGC CCCCCCTCAA GACGTTAAGT GCACCAGCTT GCGCTCCACG 
GCCATATTGA TCCTTCTGGA AGCTTTGGAG AAATGGACGG AGTACCGTGT CACCGCCGTG 
GCTTACACAG AGGTGGGACC AGGGCCCGAG AGCTCGCCCG TGGTCGTCCG CACCGATGAG 
GACGTGCCCA GCGCGCCCCC GCGGAAGGTG GAGGCGGAGG CGCTCAACGC CACGGCTATC 
CGAGTGCTGT GGCGCTCGCC CACGCCCGGC AGGCAGCACG GGCAGATCCG CGGCTACCAG 
GTCCACTATG TGCGCATGGA GGGCACCGAG GCCCGCGGGC CACCGCGCAT CAAGGACATC 
ATGCTGGCGG ATGCCCAGGA AATGGTGATC ACAAACCTCC AGCCTGAGAC TGCTTACTCT 
ATCACAGTAG CCGCGTATAC CATGAAAGGC GATGGCGCTC GCAGCAAACC GAAGGTGGTG 
GTGACCAAGG GAGCAGTGCT GGGCCGCCCC ACCCTGTCGG TGCAGCAGAC CCCCGAGGGC 
AGCCTGCTGG CGCGCTGGGA GCCCCCCGCG GACGCGGCTG AGGACCCAGT GCTTGGCTAC 
CGCCTGCAGT TTGGGCGCGA AGACGCGGCC CCGGCCACGT TGGAACTGGC GGCGTGGGAG 
CGGCGGTTCG CGGCGCCTGC ACACAAGGGC GCCACCTATG TGTTTCGGCT GGCGGCGCGG 
GGCCGCGCGG GGCTGGGCGA GGAGGCCTCG GCGGCGCTGA GCATCCCTGA GGACGCTCCG 
CGTGGCTTCC CGCAGATCCT GGGCCCCGCG GGCAACGTGT CCGCGGGCTC CGTAATACTG 
CGCTGGCTGC CACCCGTGCC CGCCGAGGGC AACGGCGCCA TCATCAAGTA CACGGTGTCC 
GTGCGGGAGG CCGGCACCCC AGGGCCCGCG ACAGAGACCG AACTGGCGGC GGCGGCCCAG 
CCGGGGGCCG AGACAGCGCT CACACTACAG GGGCTGCGGC CGGAGACGGC CTACGAGCTG 
CGCGTGCGCG CGCACACGCG TCGGGGCCCC GGCCCCTTCT CACCCCCGCT GCGATACAGG 
CTTGCGCGGG ACCCAGTCTC CCCCAAGAAC TTCAAGGTGA AGATGATCAT GAAAACTTCA 
GTGCTGCTAA GCTGGGAGTT CCCTGACAAC TATAACTCAC CCACGCCCTA CAAGATCCAG 
TACAATGGAC TCACACTGGA CGTGGATGGC CGCACTACCA AGAAGCTGAT CACGCACCTC 
AAGCCACACA CCTTCTATAA CTTCGTGCTC ACCAACCGTG GCAGCAGCCT GGGAGGCCTG 
CAGCAGACGG TCACCGCCAG GACCGCCTTC AACATGCTCA GTGGCAAGCC TAGTGTCGCC 
CCAAAGCCTG ACAACGATGG TTCCATTGTG GTCTACCTGC CTGATGGCCA GAGTCCCGTG 
ACAGTGCAGA ACTACTTCAT TGTGATGGTC CCACTTCGGA AGTCTCGTGG TGGCCAGTTC 
CCTATCCTAC TAGGTAGTCC AGAGGACATG GATCTGGAGG AGCTCATCCA GGACCTCTCC 
CGGCTGCAGA GGCGCAGCCT GCGCCACTCA AGACAGCTGG AGGTGCCTCG GCCTTACATC 
GCCGCTCGGT TCTCCATCCT GCCAGCTGTC TTCCATCCTG GGAACCAGAA GCAATATGGT 
GGCTTTGACA ACAGGGGCTT GGAGCCAGGC CACCGTTATG TCCTCTTTGT ACTTGCTGTG 
CTGCAGAAGA ATGAGCCTAC ATTTGCAGCC AGTCCCTTCT CAGACCCCTT CCAACTGGAC 
AACCCAGACC CGCAGCCCAT TGTGGATGGC GAGGAGGGCC TCATCTGGGT GATCGGGCCC 
GTGCTGGCCG TGGTCTTCAT CATCTGCATC GTAATTGCCA TCCTGCTGTA CAAGAACAAG 
CCTGACAGCA AACGCAAGGA CTCAGAGCCC CGCACCAAAT GCTTATTGAA CAATGCAGAC 
CTCGCCCCCC ATCACCCCAA GGACCCTGTG GAAATGCGAC GTATCAACTT CCAGACGCCA 
GGTATGCTCA GCCACCCGCC CATTCCCATC ACAGACATGG CTGAACACAT GGAGAGACTC 
AAAGCCAACG ACAGCCTCAA GCTCTCCCAG GAGTATGAGT CCATCGACCC TGGCCAGCAG 
TTCACTTGGG AACATTCGAA CCTGGAGGCC AACAAGCCAA AGAACCGATA CGCCAATGTC 
ATCGCCTATG ACCATTCACG AGTCATCCTG CAGCCTTTAG AAGGCATCAT GGGTAGTGAT 
TACATCAATG CCAACTATGT GGACGGCTAT CGGCGGCAGA ACGCATACAT CGCCACGCAG 
GGGCCCCTGC CTGAGACCTT TGGGGACTTC TGGCGGATGG TGTGGGAGCA GCGGTCAGCC 
ACTGTGGTCA TGATGACACG GCTGGAGGAG AAATCACGGG TCAAATGTGA CCAGTACTGG 
CCTAACCGAG GCACCGAGAC ATACGGCTTC ATCCAGGTCA CCCTACTAGA TACTATGGAG 
CTGGCCACCT TCTGTGTCAG GACCTTTTCT CTACACAAGA ATGGCTCTAG TGAGAAGCGT 
GAGGTACGAC ATTTTCAGTT CACAGCATGG CCTGACCACG GGGTACCCGA GTACCCCACA 
CCCTTCCTGG CGTTTCTGCG CAGAGTCAAG ACCTGCAACC CGCCTGACGC TGGCCCAGTT 
GTGGTCCACT GCAGCGCGGG TGTGGGGCGT ACTGGCTGCT TCATTGTAAT TGATGCCATG 
TTGGAGCGCA TCAGAACAGA GAAGACGGTG GATGTGTACG GACACGTGAC ACTCATGCGG 
TCACAGCGCA ACTACATGGT GCAGACAGAG GATCAGTATA GCTTCATCCA CGAGGCACTG 
CTGGAGGCTG TGGGCTGTGG CAATACCGAG GTCCCCGCGC GCAGCCTCTA CACCTATATC 
CAGAAGCTGG CCCAGGTGGA GCCTGGCGAG CATGTCACAG GAATGGAGCT TGAGTTCAAG 
AGGCTTGCCA GCTCCAAGGC ACACACTTCG AGATTCATCA CTGCCAGCCT GCCTTGCAAC 
AAGTTTAAGA ACCGCCTGGT GAACATCCTG CCGTACGAGA GCTCGCGTGT CTGCCTGCAG 
CCCATTCGTG GTGTCGAGGG CTCTGACTAC ATCAATGCCA GCTTCATCGA CGGCTACAGA 
CAGCAGAAAG CCTACATTGC AACGCAGGGT CCACTGGCAG AGACCACAGA GGACTTCTGG 
CGTGCCCTGT GGGAGAACAA CTCCACTATT GTGGTAATGC TCACCAAGCT CCGCGAGATG 
GGCCGGGAGA AGTGCCACCA GTACTGGCCA GCTGAACGCT CTGCCCGCTA CCAGTACTTT 
GTGGTTGACC CGATGGCAGA GTATAACATG CCACAGTACA TTCTGCGTGA GTTTAAGGTC 
ACAGATGCCC GGGATGGCCA GTCCCGGACC GTCCGACAGT TCCAGTTCAC GGACTGGCCA 
GAGCAGGGTG CACCCAAGTC AGGGGAAGGC TTCATTGACT TCATCGGCCA AGTGCATAAG 
ACCAAGGAGC AGTTTGGCCA GGATGGCCCC ATCTCGGTGC ACTGTAGTGC TGGAGTGGGC 
AGGACCGGAG TATTCATCAC TCTGAGCATC GTGCTGGAGC GAATGCGCTA CGAGGGGGTG 
GTGGACATTT TCCAGACAGT GAAGGTGCTT CGGACCCAGC GGCCTGCCAT GGTGCAGACA 
GAGGATGAGT ACCAGTTCTG CTTCCAGGCG GCGTTGGAAT ACCTGGGCAG CTTTGATCAT 
TATGCAACAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Aberrant astrocytic expression of chondroitin sulfate proteoglycan receptors in a rat model of amyotrophic lateral sclerosis.
Journal of neuroscience research96(2)222-233(2018 Feb)
Shijo T,Warita H,Suzuki N,Kitajima Y,Ikeda K,Akiyama T,Ono H,Mitsuzawa S,Nishiyama A,Izumi R,Aoki M

SALM5 trans-synaptically interacts with LAR-RPTPs in a splicing-dependent manner to regulate synapse development.
Scientific reports626676(2016 May)
Choi Y,Nam J,Whitcomb DJ,Song YS,Kim D,Jeon S,Um JW,Lee SG,Woo J,Kwon SK,Li Y,Mah W,Kim HM,Ko J,Cho K,Kim E

Enhanced regeneration and functional recovery after spinal root avulsion by manipulation of the proteoglycan receptor PTP?.
Scientific reports514923(2015 Oct)
Li H,Wong C,Li W,Ruven C,He L,Wu X,Lang BT,Silver J,Wu W

Protein Tyrosine Phosphatase PTPRS Is an Inhibitory Receptor on Human and Murine Plasmacytoid Dendritic Cells.
Immunity43(2)277-88(2015 Aug)
Bunin A,Sisirak V,Ghosh HS,Grajkowska LT,Hou ZE,Miron M,Yang C,Ceribelli M,Uetani N,Chaperot L,Plumas J,Hendriks W,Tremblay ML,H?cker H,Staudt LM,Green PH,Bhagat G,Reizis B

PTP? functions as a presynaptic receptor for the glypican-4/LRRTM4 complex and is essential for excitatory synaptic transmission.
Proceedings of the National Academy of Sciences of the United States of America112(6)1874-9(2015 Feb)
Ko JS,Pramanik G,Um JW,Shim JS,Lee D,Kim KH,Chung GY,Condomitti G,Kim HM,Kim H,de Wit J,Park KS,Tabuchi K,Ko J

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Ptprs cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

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