Htr2c cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Htr2c
Entrez Gene ID	25187
Full Name	5-hydroxytryptamine receptor 2C
Synonyms	5-HT2C,5-HTR2C,5HT-1C
General protein information	Preferred Names 5-hydroxytryptamine receptor 2C Names 5-hydroxytryptamine receptor 2C 5-HT-1C 5-HT1C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 5-hydroxytryptamine receptor 1C serotonin 1c receptor serotonin receptor 2C
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: X Map Location: Xq34
Summary	Serotonin (5-hydroxytryptamine, 5-HT), a neurotransmitter, elicits a wide array of physiological effects by binding to several receptor subtypes, including the 5-HT2 family of seven-transmembrane-spanning, G-protein-coupled receptors, which activate phospholipase C and D signaling pathways. This gene encodes the 2C subtype of serotonin receptor and its mRNA is subject to multiple RNA editing events, where genomically encoded adenosine residues are converted to inosines. RNA editing is predicted to alter amino acids within the second intracellular loop of the 5-HT2C receptor and generate receptor isoforms that differ in their ability to interact with G proteins and the activation of phospholipase C and D signaling cascades, thus modulating serotonergic neurotransmission in the central nervous system. Studies in rodents show altered patterns of RNA editing in response to drug treatments and stressful situations. [provided by RefSeq, Jul 2008].

mRNA and Protein(s)

mRNA	Protein	Name
NM_012765.3	NP_036897.2	5-hydroxytryptamine receptor 2C
XM_017601920.1	XP_017457409.1	5-hydroxytryptamine receptor 2C isoform X1

Pathways from BioSystems

Homologies

Bos taurus (cattle)	HTR2C	XP_005227998.1
Mus musculus (house mouse)	Htr2c	NP_032338.3
Canis lupus familiaris (dog)	HTR2C	NP_001006649.1
Anopheles gambiae (African malaria mosquito)	GPR5HT2A	XP_307953.2
Homo sapiens (human)	HTR2C	NP_001243689.1
Pan troglodytes (chimpanzee)	HTR2C	NP_001029104.2
	HTR2C	XP_001101997.1
Rattus norvegicus (Norway rat)	Htr2c	NP_036897.2

Gene Ontology
Bibliography

Related articles in PubMed

Expression of Serotonin2C Receptors in Pyramidal and GABAergic Neurons of Rat Prefrontal Cortex: A Comparison with Striatum.
Santana N, Artigas F
Cerebral cortex (New York, N.Y. : 1991)27(6)3125-3139(2017 Jun)

Heterodimers of serotonin receptor subtypes 2 are driven by 5-HT
Moutkine I, Quentin E, Guiard BP, Maroteaux L, Doly S
The Journal of biological chemistry292(15)6352-6368(2017 04)

5-HT
Ji G, Zhang W, Mahimainathan L, Narasimhan M, Kiritoshi T, Fan X, Wang J, Green TA, Neugebauer V
The Journal of neuroscience : the official journal of the Society for Neuroscience37(6)1378-1393(2017 Feb)

Regulation of serotonin-2C receptor G-protein coupling by RNA editing.
Burns CM, Chu H, Rueter SM, Hutchinson LK, Canton H, Sanders-Bush E, Emeson RB
Nature387(6630)303-8(1997 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Knockdown of 5-HT2C in the amygdala decreases neuronal activity and inhibits neuropathic-pain-related behaviors.
Title: 5-HT

Results demonstrate that the incubation of cue reactivity during prolonged abstinence from cocaine self-administration is associated with lower potency of the selective 5-HT2CR agonist WAY163909 to suppress cue reactivity, with no evident change in agonist efficacy
Title: Incubation of cocaine cue reactivity associates with neuroadaptations in the cortical serotonin (5-HT) 5-HT2C receptor (5-HT2CR) system.

These findings reveal a 5-hydroxytryptamine-mediated mechanism underlying the programming of susceptibility to obesity.
Title: 5-HT2A and 5-HT2C receptors as hypothalamic targets of developmental programming in male rats.

the activation of 5-HT2A/C receptors reduced Glycine receptor current, possibly through interfering with cytoskeleton-dependent trafficking or clustering of Glycine receptors.
Title: Activation of 5-HT2A/C receptor reduces glycine receptor-mediated currents in cultured auditory cortical neurons.

Study suggested that there is an interactive relationship between the medial prefrontal cortex 5-HT2AR and 5-HT2CR, and that a 5-HT2AR:5-HT2CR imbalance may be a functionally relevant mechanism underlying motor impulsivity
Title: Serotonin (5-HT) 5-HT2A Receptor (5-HT2AR):5-HT2CR Imbalance in Medial Prefrontal Cortex Associates with Motor Impulsivity.

The following Htr2c gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Htr2c cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa40009	NM_012765.3 Latest version!	Rattus norvegicus 5-hydroxytryptamine receptor 2C (Htr2c), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$272.30 $389.00
ORa63011	XM_017601920.1 Latest version!	Rattus norvegicus 5-hydroxytryptamine receptor 2C (Htr2c), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Htr2c ( NM_012765.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_036897.2 Rattus norvegicus 5-hydroxytryptamine receptor 2C (Htr2c), mRNA.

Price & Availability↑

CloneID	ORa40009
Clone ID Related Accession (Same CDS sequence)	NM_012765.3
Accession Version	NM_012765.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1383bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Rattus norvegicus(Norway rat)
Product	5-hydroxytryptamine receptor 2C
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from U35315.1, AABR07041052.1, AABR07041066.1, CB613191.1, CB784937.1, CB557712.1, BF285550.1, BF415855.1 and BF409467.1. On Jan 2, 2008 this sequence version replaced NM_012765.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## undergoes RNA editing :: PMID: 9153397 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGTGAACC TTGGCAACGC GGTGCGCTCG CTCCTGATGC ACCTAATCGG CCTATTGGTT 
TGGCAATTCG ATATTTCCAT AAGTCCAGTA GCAGCTATAG TAACTGACAC TTTTAATTCC 
TCCGATGGTG GACGCTTGTT TCAATTCCCG GACGGGGTAC AAAACTGGCC AGCACTTTCA 
ATCGTCGTGA TTATAATCAT GACAATAGGG GGCAACATTC TTGTTATCAT GGCAGTAAGC 
ATGGAGAAGA AACTGCACAA TGCAACCAAT TACTTCTTAA TGTCCCTAGC CATTGCTGAT 
ATGCTGGTGG GACTACTTGT CATGCCCCTG TCCCTGCTTG CTATTCTTTA TGATTATGTC 
TGGCCTTTAC CTAGATATTT GTGCCCCGTC TGGATTTCAC TAGATGTGCT ATTTTCAACT 
GCGTCCATCA TGCACCTCTG CGCCATATCG CTGGACCGGT ATGTAGCAAT ACGTAATCCT 
ATTGAGCATA GCCGGTTCAA TTCGCGGACT AAGGCCATCA TGAAGATTGC CATCGTTTGG 
GCAATATCAA TAGGAGTTTC AGTTCCTATC CCTGTGATTG GACTGAGGGA CGAAAGCAAA 
GTGTTCGTGA ATAACACCAC GTGCGTGCTC AATGACCCCA ACTTCGTTCT CATCGGGTCC 
TTCGTGGCAT TCTTCATCCC GTTGACGATT ATGGTGATCA CCTACTTCTT AACGATCTAC 
GTCCTGCGCC GTCAAACTCT GATGTTACTT CGAGGTCACA CCGAGGAGGA ACTGGCTAAT 
ATGAGCCTGA ACTTTCTGAA CTGCTGCTGC AAGAAGAATG GTGGTGAGGA AGAGAACGCT 
CCGAACCCTA ATCCAGATCA GAAACCACGT CGAAAGAAGA AAGAAAAGCG TCCCAGAGGC 
ACCATGCAAG CTATCAACAA CGAAAAGAAA GCTTCCAAAG TCCTTGGCAT TGTATTCTTT 
GTGTTTCTGA TCATGTGGTG CCCGTTTTTC ATCACCAATA TCCTGTCGGT TCTTTGTGGG 
AAGGCCTGTA ACCAAAAGCT AATGGAGAAG CTTCTCAATG TGTTTGTGTG GATTGGCTAT 
GTGTGTTCAG GCATCAATCC TCTGGTGTAC ACTCTCTTTA ATAAAATTTA CCGAAGGGCT 
TTCTCTAAAT ATTTGCGCTG CGATTATAAG CCAGACAAAA AGCCTCCTGT TCGACAGATT 
CCTAGGGTTG CTGCCACTGC TTTGTCTGGG AGGGAGCTCA ATGTTAACAT TTATCGGCAT 
ACCAATGAAC GTGTGGCTAG GAAAGCTAAT GACCCTGAGC CTGGCATAGA GATGCAGGTG 
GAGAACTTAG AGCTGCCAGT CAACCCCTCT AATGTGGTCA GCGAGAGGAT TAGTAGTGTG 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036897.2
CDS	344..1726
Translation	MVNLGNAVRSLLMHLIGLLVWQFDISISPVAAIVTDTFNSSDGGRLFQFPDGVQNWPALSIVVIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVWPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWAISIGVSVPIPVIGLRDESKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYFLTIYVLRRQTLMLLRGHTEEELANMSLNFLNCCCKKNGGEEENAPNPNPDQKPRRKKKEKRPRGTMQAINNEKKASKVLGIVFFVFLIMWCPFFITNILSVLCGKACNQKLMEKLLNVFVWIGYVCSGINPLVYTLFNKIYRRAFSKYLRCDYKPDKKPPVRQIPRVAATALSGRELNVNIYRHTNERVARKANDPEPGIEMQVENLELPVNPSNVVSERISSV

Target ORF information:

RefSeq Version	NM_012765.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus 5-hydroxytryptamine receptor 2C (Htr2c), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012765.3

ORF Insert Sequence:

ATGGTGAACC TTGGCAACGC GGTGCGCTCG CTCCTGATGC ACCTAATCGG CCTATTGGTT 
TGGCAATTCG ATATTTCCAT AAGTCCAGTA GCAGCTATAG TAACTGACAC TTTTAATTCC 
TCCGATGGTG GACGCTTGTT TCAATTCCCG GACGGGGTAC AAAACTGGCC AGCACTTTCA 
ATCGTCGTGA TTATAATCAT GACAATAGGG GGCAACATTC TTGTTATCAT GGCAGTAAGC 
ATGGAGAAGA AACTGCACAA TGCAACCAAT TACTTCTTAA TGTCCCTAGC CATTGCTGAT 
ATGCTGGTGG GACTACTTGT CATGCCCCTG TCCCTGCTTG CTATTCTTTA TGATTATGTC 
TGGCCTTTAC CTAGATATTT GTGCCCCGTC TGGATTTCAC TAGATGTGCT ATTTTCAACT 
GCGTCCATCA TGCACCTCTG CGCCATATCG CTGGACCGGT ATGTAGCAAT ACGTAATCCT 
ATTGAGCATA GCCGGTTCAA TTCGCGGACT AAGGCCATCA TGAAGATTGC CATCGTTTGG 
GCAATATCAA TAGGAGTTTC AGTTCCTATC CCTGTGATTG GACTGAGGGA CGAAAGCAAA 
GTGTTCGTGA ATAACACCAC GTGCGTGCTC AATGACCCCA ACTTCGTTCT CATCGGGTCC 
TTCGTGGCAT TCTTCATCCC GTTGACGATT ATGGTGATCA CCTACTTCTT AACGATCTAC 
GTCCTGCGCC GTCAAACTCT GATGTTACTT CGAGGTCACA CCGAGGAGGA ACTGGCTAAT 
ATGAGCCTGA ACTTTCTGAA CTGCTGCTGC AAGAAGAATG GTGGTGAGGA AGAGAACGCT 
CCGAACCCTA ATCCAGATCA GAAACCACGT CGAAAGAAGA AAGAAAAGCG TCCCAGAGGC 
ACCATGCAAG CTATCAACAA CGAAAAGAAA GCTTCCAAAG TCCTTGGCAT TGTATTCTTT 
GTGTTTCTGA TCATGTGGTG CCCGTTTTTC ATCACCAATA TCCTGTCGGT TCTTTGTGGG 
AAGGCCTGTA ACCAAAAGCT AATGGAGAAG CTTCTCAATG TGTTTGTGTG GATTGGCTAT 
GTGTGTTCAG GCATCAATCC TCTGGTGTAC ACTCTCTTTA ATAAAATTTA CCGAAGGGCT 
TTCTCTAAAT ATTTGCGCTG CGATTATAAG CCAGACAAAA AGCCTCCTGT TCGACAGATT 
CCTAGGGTTG CTGCCACTGC TTTGTCTGGG AGGGAGCTCA ATGTTAACAT TTATCGGCAT 
ACCAATGAAC GTGTGGCTAG GAAAGCTAAT GACCCTGAGC CTGGCATAGA GATGCAGGTG 
GAGAACTTAG AGCTGCCAGT CAACCCCTCT AATGTGGTCA GCGAGAGGAT TAGTAGTGTG 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Htr2c ( XM_017601920.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017457409.1 Rattus norvegicus 5-hydroxytryptamine receptor 2C (Htr2c), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa63011
Clone ID Related Accession (Same CDS sequence)	XM_017601920.1
Accession Version	XM_017601920.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1383bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	5-hydroxytryptamine receptor 2C isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005120.4) and transcript sequence (U35315.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 38 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END##

ATGGTGAACC TTGGCAACGC GGTGCGCTCG CTCCTGATGC ACCTAATCGG CCTATTGGTT 
TGGCAATTCG ATATTTCCAT AAGTCCAGTA GCAGCTATAG TAACTGACAC TTTTAATTCC 
TCCGATGGTG GACGCTTGTT TCAATTCCCG GACGGGGTCC AAACCTGGCC AGCACTTTCA 
ATCGTCGTGA TTATAATCAT GACAATAGGG GGCAACATTC TTGTTATCAT GGCAGTAAGC 
ATGGAGAAGA AACTGCACAA TGCAACCAAT TACTTCTTAA TGTCCCTAGC CATTGCTGAT 
ATGCTGGTGG GACTACTTGT CATGCCCCTG TCCCTGCTTG CTATTCTTTA TGATTATGTC 
TGGCCTTTAC CTAGATATTT GTGCCCCGTC TGGATTTCAC TAGATGTGCT ATTTTCAACT 
GCGTCCATCA TGCACCTCTG CGCCATATCG CTGGACCGGT ATGTAGCAAT ACGTAATCCT 
ATTGAGCATA GCCGGTTCAA TTCGCGGACT AAGGCCATCA TGAAGATTGC CATCGTTTGG 
GCAATATCAA TAGGAGTTTC AGTTCCTATC CCTGTGATTG GACTGAGGGA CGAAAGCAAA 
GTGTTCGTGA ATAACACCAC GTGCGTGCTC AATGACCCCA ACTTCGTTCT CATCGGGTCC 
TTCGTGGCAT TCTTCATCCC GTTGACGATT ATGGTGATCA CCTACTTCTT AACGATCTAC 
GTCCTGCGCC GTCAAACTCT GATGTTACTT CGAGGTCACA CCGAGGAGGA ACTGGCTAAT 
ATGAGCCTGA ACTTTCTGAA CTGCTGCTGC AAGAAGAATG GTGGTGAGGA AGAGAACGCT 
CCGAACCCTA ATCCAGATCA GAAACCACGT CGAAAGAAGA AAGAAAAGCG TCCCAGAGGC 
ACCATGCAAG CTATCAACAA CGAAAAGAAA GCTTCCAAAG TCCTTGGCAT TGTATTCTTT 
GTGTTTCTGA TCATGTGGTG CCCGTTTTTC ATCACCAATA TCCTGTCGGT TCTTTGTGGG 
AAGGCCTGTA ACCAAAAGCT AATGGAGAAG CTTCTCAATG TGTTTGTGTG GATTGGCTAT 
GTGTGTTCAG GCATCAATCC TCTGGTGTAC ACTCTCTTTA ATAAAATTTA CCGAAGGGCT 
TTCTCTAAAT ATTTGCGCTG CGATTATAAG CCAGACAAAA AGCCTCCTGT TCGACAGATT 
CCTAGGGTTG CTGCCACTGC TTTGTCTGGG AGGGAGCTCA ATGTTAACAT TTATCGGCAT 
ACCAATGAAC GTGTGGCTAG GAAAGCTAAT GACCCTGAGC CTGGCATAGA GATGCAGGTG 
GAGAACTTAG AGCTGCCAGT CAACCCCTCT AATGTGGTCA GCGAGAGGAT TAGTAGTGTG 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017457409.1
CDS	714..2096
Translation	MVNLGNAVRSLLMHLIGLLVWQFDISISPVAAIVTDTFNSSDGGRLFQFPDGVQTWPALSIVVIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVWPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWAISIGVSVPIPVIGLRDESKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYFLTIYVLRRQTLMLLRGHTEEELANMSLNFLNCCCKKNGGEEENAPNPNPDQKPRRKKKEKRPRGTMQAINNEKKASKVLGIVFFVFLIMWCPFFITNILSVLCGKACNQKLMEKLLNVFVWIGYVCSGINPLVYTLFNKIYRRAFSKYLRCDYKPDKKPPVRQIPRVAATALSGRELNVNIYRHTNERVARKANDPEPGIEMQVENLELPVNPSNVVSERISSV

Target ORF information:

RefSeq Version	XM_017601920.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus 5-hydroxytryptamine receptor 2C (Htr2c), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017601920.1

ORF Insert Sequence:

ATGGTGAACC TTGGCAACGC GGTGCGCTCG CTCCTGATGC ACCTAATCGG CCTATTGGTT 
TGGCAATTCG ATATTTCCAT AAGTCCAGTA GCAGCTATAG TAACTGACAC TTTTAATTCC 
TCCGATGGTG GACGCTTGTT TCAATTCCCG GACGGGGTCC AAACCTGGCC AGCACTTTCA 
ATCGTCGTGA TTATAATCAT GACAATAGGG GGCAACATTC TTGTTATCAT GGCAGTAAGC 
ATGGAGAAGA AACTGCACAA TGCAACCAAT TACTTCTTAA TGTCCCTAGC CATTGCTGAT 
ATGCTGGTGG GACTACTTGT CATGCCCCTG TCCCTGCTTG CTATTCTTTA TGATTATGTC 
TGGCCTTTAC CTAGATATTT GTGCCCCGTC TGGATTTCAC TAGATGTGCT ATTTTCAACT 
GCGTCCATCA TGCACCTCTG CGCCATATCG CTGGACCGGT ATGTAGCAAT ACGTAATCCT 
ATTGAGCATA GCCGGTTCAA TTCGCGGACT AAGGCCATCA TGAAGATTGC CATCGTTTGG 
GCAATATCAA TAGGAGTTTC AGTTCCTATC CCTGTGATTG GACTGAGGGA CGAAAGCAAA 
GTGTTCGTGA ATAACACCAC GTGCGTGCTC AATGACCCCA ACTTCGTTCT CATCGGGTCC 
TTCGTGGCAT TCTTCATCCC GTTGACGATT ATGGTGATCA CCTACTTCTT AACGATCTAC 
GTCCTGCGCC GTCAAACTCT GATGTTACTT CGAGGTCACA CCGAGGAGGA ACTGGCTAAT 
ATGAGCCTGA ACTTTCTGAA CTGCTGCTGC AAGAAGAATG GTGGTGAGGA AGAGAACGCT 
CCGAACCCTA ATCCAGATCA GAAACCACGT CGAAAGAAGA AAGAAAAGCG TCCCAGAGGC 
ACCATGCAAG CTATCAACAA CGAAAAGAAA GCTTCCAAAG TCCTTGGCAT TGTATTCTTT 
GTGTTTCTGA TCATGTGGTG CCCGTTTTTC ATCACCAATA TCCTGTCGGT TCTTTGTGGG 
AAGGCCTGTA ACCAAAAGCT AATGGAGAAG CTTCTCAATG TGTTTGTGTG GATTGGCTAT 
GTGTGTTCAG GCATCAATCC TCTGGTGTAC ACTCTCTTTA ATAAAATTTA CCGAAGGGCT 
TTCTCTAAAT ATTTGCGCTG CGATTATAAG CCAGACAAAA AGCCTCCTGT TCGACAGATT 
CCTAGGGTTG CTGCCACTGC TTTGTCTGGG AGGGAGCTCA ATGTTAACAT TTATCGGCAT 
ACCAATGAAC GTGTGGCTAG GAAAGCTAAT GACCCTGAGC CTGGCATAGA GATGCAGGTG 
GAGAACTTAG AGCTGCCAGT CAACCCCTCT AATGTGGTCA GCGAGAGGAT TAGTAGTGTG 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Expression of Serotonin2C Receptors in Pyramidal and GABAergic Neurons of Rat Prefrontal Cortex: A Comparison with Striatum.
Cerebral cortex (New York, N.Y. : 1991)27(6)3125-3139(2017 Jun)
Santana N,Artigas F

Heterodimers of serotonin receptor subtypes 2 are driven by 5-HT
The Journal of biological chemistry292(15)6352-6368(2017 04)
Moutkine I,Quentin E,Guiard BP,Maroteaux L,Doly S

5-HT
The Journal of neuroscience : the official journal of the Society for Neuroscience37(6)1378-1393(2017 Feb)
Ji G,Zhang W,Mahimainathan L,Narasimhan M,Kiritoshi T,Fan X,Wang J,Green TA,Neugebauer V

Regulation of serotonin-2C receptor G-protein coupling by RNA editing.
Nature387(6630)303-8(1997 May)
Burns CM,Chu H,Rueter SM,Hutchinson LK,Canton H,Sanders-Bush E,Emeson RB

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Htr2c cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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