Scnn1b cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Scnn1b
Entrez Gene ID	24767
Full Name	sodium channel epithelial 1 beta subunit
Synonyms	RNENACB
General protein information	Preferred Names sodium channel epithelial 1 beta subunit Names amiloride-sensitive sodium channel subunit beta SCNEB beta-ENaC beta-NaCH epithelial Na(+) channel subunit beta nonvoltage-gated sodium channel 1 subunit beta sodium channel, non-voltage-gated 1, beta subunit sodium channel, nonvoltage-gated 1, beta sodium channel, nonvoltage-gated, type I, beta
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q36
Summary	acts as an epithelial sodium ion channel; regulates salt and fluid transport in the kidney [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_008759685.2	XP_008757907.1	amiloride-sensitive sodium channel subunit beta isoform X2
XM_008759684.2	XP_008757906.1	amiloride-sensitive sodium channel subunit beta isoform X1
XM_008759682.2	XP_008757904.1	amiloride-sensitive sodium channel subunit beta isoform X1
XM_008759686.2	XP_008757908.1	amiloride-sensitive sodium channel subunit beta isoform X3
NM_012648.1	NP_036780.1	amiloride-sensitive sodium channel subunit beta
XM_008759683.2	XP_008757905.1	amiloride-sensitive sodium channel subunit beta isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	SCNN1B	NP_000327.2
Rattus norvegicus (Norway rat)	Scnn1b	NP_036780.1
Gallus gallus (chicken)	SCNN1B	XP_425247.3
Xenopus tropicalis (tropical clawed frog)	scnn1b	NP_001072437.1
	SCNN1B	XP_001093933.1
Canis lupus familiaris (dog)	SCNN1B	XP_005621478.1
Mus musculus (house mouse)	Scnn1b	NP_035455.1
Bos taurus (cattle)	SCNN1B	NP_001091544.1
Pan troglodytes (chimpanzee)	SCNN1B	XP_001161438.2

Gene Ontology
Bibliography

Related articles in PubMed

???-ENaC is inhibited by CFTR but stimulated by cAMP in
Rauh R, Hoerner C, Korbmacher C
American journal of physiology. Lung cellular and molecular physiology312(2)L277-L287(2017 Feb)

Altered ENaC is Associated With Aortic Baroreceptor Dysfunction in Chronic Heart Failure.
Li YL, Zhang D, Tu H, Muelleman RL
American journal of hypertension29(5)582-9(2016 May)

[Expression of Catechol-O-Methyltransferase (Comt), Mineralocorticoid Receptor (Mlr), and Epithelial Sodium Channel (ENaC) Genes in Kidneys of Hypertensive ISIAH Rats at Rest and during Response to Stress].
Abramova TO, Smolenskaya SE, Antonov EV, Redina OE, Markel AL
Genetika52(2)206-14(2016 Feb)

Heme oxygenase-1 promotes migration and ?-epithelial Na+ channel expression in cytotrophoblasts and ischemic placentas.
Warrington JP, Coleman K, Skaggs C, Hosick PA, George EM, Stec DE, Ryan MJ, Granger JP, Drummond HA
American journal of physiology. Regulatory, integrative and comparative physiology306(9)R641-6(2014 May)

Identification of the SPLUNC1 ENaC-inhibitory domain yields novel strategies to treat sodium hyperabsorption in cystic fibrosis airway epithelial cultures.
Hobbs CA, Blanchard MG, Alijevic O, Tan CD, Kellenberger S, Bencharit S, Cao R, Kesimer M, Walton WG, Henderson AG, Redinbo MR, Stutts MJ, Tarran R
American journal of physiology. Lung cellular and molecular physiology305(12)L990-L1001(2013 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

deltabetagamma-ENaC is inhibited by CFTR but activated by cyclic AMP.
Title: ???-ENaC is inhibited by CFTR but stimulated by cAMP in

Decreased expression of Scnn1b/g and activation of ENaC could be involved in attenuation of the aortic baroreceptor sensitivity in congestive heart failure.
Title: Altered ENaC is Associated With Aortic Baroreceptor Dysfunction in Chronic Heart Failure.

The discovered changes in the expression level of catechol-o-methyltransferase , mineralocorticoid receptor , and b-subunit of epithelial sodium channel confirm their involvement in increased sympathetic stimulation of the of hypertensive rats
Title: [Expression of Catechol-O-Methyltransferase (Comt), Mineralocorticoid Receptor (Mlr), and Epithelial Sodium Channel (ENaC) Genes in Kidneys of Hypertensive ISIAH Rats at Rest and during Response to Stress].

Suggest that beta-ENaC mediates cytotrophoblast migration and increasing beta-ENaC expression by HO-1 induction enhances migration.
Title: Heme oxygenase-1 promotes migration and ?-epithelial Na+ channel expression in cytotrophoblasts and ischemic placentas.

Nedd4-2-mediated ubiquitination of beta-ENaC leading to endocytosis and degradation of apical Na(+) channels is a key feature of hypoxia-induced inhibition of transepithelial alveolar Na(+) transport.
Title: Hypoxia-induced inhibition of epithelial Na(+) channels in the lung. Role of Nedd4-2 and the ubiquitin-proteasome pathway.

The following Scnn1b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Scnn1b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa13101	NM_012648.1 Latest version!	Rattus norvegicus sodium channel epithelial 1 subunit beta (Scnn1b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$377.30 $539.00
ORa42953	XM_008759682.2 Latest version!	Rattus norvegicus sodium channel epithelial 1 beta subunit (Scnn1b), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa42953	XM_008759684.2 Latest version!	Rattus norvegicus sodium channel epithelial 1 beta subunit (Scnn1b), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa42953	XM_008759683.2 Latest version!	Rattus norvegicus sodium channel epithelial 1 beta subunit (Scnn1b), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa42954	XM_008759685.2 Latest version!	Rattus norvegicus sodium channel epithelial 1 beta subunit (Scnn1b), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa42955	XM_008759686.2 Latest version!	Rattus norvegicus sodium channel epithelial 1 beta subunit (Scnn1b), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Scnn1b ( NM_012648.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_036780.1 Rattus norvegicus sodium channel epithelial 1 subunit beta (Scnn1b), mRNA.

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CloneID	ORa13101
Clone ID Related Accession (Same CDS sequence)	NM_012648.1
Accession Version	NM_012648.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1917bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-10
Organism	Rattus norvegicus(Norway rat)
Product	amiloride-sensitive sodium channel subunit beta
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from X77932.1. Sequence Note: This sequence has been modified as follows: removed 17 bp suspected to be vector contamination from the 5' end. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X77932.1, U35174.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689597, SAMEA2689599 [ECO:0000348] ##Evidence-Data-END##

ATGCCAGTGA AGAAGTACCT GCTGAAGTGC CTGCACAGGC TGCAGAAGGG CCCAGGCTAC 
ACCTACAAGG AGCTGCTAGT GTGGTACTGC AACAACACCA ACACACACGG CCCCAAACGC 
ATCATCTGCG AGGGGCCCAA GAAGAAGGCC ATGTGGTTCC TGCTCACGCT GCTCTTCGCC 
TGCCTGGTGT GCTGGCAGTG GGGCGTCTTC ATCCAGACCT ACCTGAGCTG GGAGGTCAGC 
GTCTCGCTCT CCATGGGCTT CAAGACCATG AACTTCCCAG CAGTCACCGT CTGCAATTCC 
AGCCCCTTCC AGTACTCCAA GGTCAAGCAC TTGCTGAAGG ACTTGTACAA GCTGATGGAG 
GCTGTCCTGG ACAAGATTCT GGCTCCGAAG TCCAGCCACA CCAACACCAC CAGTACCCTG 
AACTTTACCA TCTGGAACCA CACGCCCCTG GTCCTTATTG ATGAGCGGAA CCCTGACCAT 
CCAGTGGTCC TCAACTTGTT TGGGGACAGC CACAACAGCA GCAACCCAGC CCCAGGAAGC 
ACCTGTAATG CCCAAGGGTG CAAAGTGGCC ATGAGGCTGT GCAGTGCCAA TGGGACCGTG 
TGTACCTTCC GAAACTTCAC CAGTGCCACC CAGGCCGTGA CTGAGTGGTA CATCCTGCAG 
GCCACCAACA TCTTCTCACA AGTGCTCCCC CAGGACCTGG TGGGGATGGG CTATGCTCCT 
GATCGCATAA TCCTAGCCTG TCTGTTTGGA ACGGAGCCCT GCAGTCATCG GAACTTCACA 
CCTATCTTCT ACCCTGATTA TGGCAACTGC TACATCTTCA ACTGGGGCAT GACAGAGAAG 
GCACTTCCTT CTGCCAACCC TGGGACTGAA TTTGGTCTCA AGTTGATCCT GGACATTGGT 
CAGGAGGACT ATGTCCCCTT CCTTGCGTCC ACAGCAGGGG CTAGGCTGAT GCTCCACGAG 
CAGAGGACAT ACCCCTTCAT TAGAGAAGAG GGCATCTATG CCATGGCAGG AACTGAGACT 
TCTATTGGGG TGCTGCTGGA CAAGCTGCAG GGCAAGGGGG AGCCATACAG TCCCTGCACC 
ATGAACGGCT CCGACGTTGC CATTCAGAAC CTCTACAGTG ACTACAACAC GACCTATTCC 
ATCCAGGCCT GCCTTCATTC CTGTTTCCAA GACCACATGA TCCATAACTG CAGCTGTGGT 
CACTACTTGT ACCCTTTGCC TGCTGGGGAG AAATACTGCA ACAACAGAGA CTTCCCAGAC 
TGGGCCTACT GCTACCTAAG CCTACAGATG AGTGTGGTCC AGAGAGAGAC CTGCCTCAGC 
ATGTGCAAGG AGTCCTGCAA CGACACCCAG TATAAGATGA CCATCTCCAT GGCTGACTGG 
CCATCCGAGG CCTCTGAGGA TTGGATCCTA CATGTCCTGT CTCAGGAGCG GGACCAGAGC 
TCAAATATCA CCCTGAGCAG GAAGGGTATT GTCAAGCTCA ATATCTACTT CCAAGAGTTC 
AACTACCGTA CCATCGAGGA ATCGCCGGCC AACAATATCG TGTGGCTGCT CTCTAACCTG 
GGTGGCCAGT TTGGCTTCTG GATGGGGGGC TCGGTGCTGT GCCTCATTGA GTTTGGGGAG 
ATCATTATCG ACTTCATTTG GATCACTGTC ATCAAGCTAG TGGCCTCCTG TAAAGGCCTG 
CGCAGGAGGC GGCCACAGCG ACCCTACACT GGCCCGCCGC CCACTGTGGC CGAGCTGGTG 
GAGGCCCACA CCAACTGTGT CTTCCAGCCT GACACAACCA GCTGCAGGCC CAATGCCGAG 
GTCTACCCTG ACCAACAGAC TCTGCCCATT CCGGGCACTC CACCTCCCAA CTATGACTCC 
CTGAGGCTGC AGCCGCTGGA CACCATGGAG TCTGACAGCG AGGTGGAGGC CATCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036780.1
CDS	56..1972
Translation	MPVKKYLLKCLHRLQKGPGYTYKELLVWYCNNTNTHGPKRIICEGPKKKAMWFLLTLLFACLVCWQWGVFIQTYLSWEVSVSLSMGFKTMNFPAVTVCNSSPFQYSKVKHLLKDLYKLMEAVLDKILAPKSSHTNTTSTLNFTIWNHTPLVLIDERNPDHPVVLNLFGDSHNSSNPAPGSTCNAQGCKVAMRLCSANGTVCTFRNFTSATQAVTEWYILQATNIFSQVLPQDLVGMGYAPDRIILACLFGTEPCSHRNFTPIFYPDYGNCYIFNWGMTEKALPSANPGTEFGLKLILDIGQEDYVPFLASTAGARLMLHEQRTYPFIREEGIYAMAGTETSIGVLLDKLQGKGEPYSPCTMNGSDVAIQNLYSDYNTTYSIQACLHSCFQDHMIHNCSCGHYLYPLPAGEKYCNNRDFPDWAYCYLSLQMSVVQRETCLSMCKESCNDTQYKMTISMADWPSEASEDWILHVLSQERDQSSNITLSRKGIVKLNIYFQEFNYRTIEESPANNIVWLLSNLGGQFGFWMGGSVLCLIEFGEIIIDFIWITVIKLVASCKGLRRRRPQRPYTGPPPTVAELVEAHTNCVFQPDTTSCRPNAEVYPDQQTLPIPGTPPPNYDSLRLQPLDTMESDSEVEAI

Target ORF information:

RefSeq Version	NM_012648.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus sodium channel epithelial 1 subunit beta (Scnn1b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012648.1

ORF Insert Sequence:

ATGCCAGTGA AGAAGTACCT GCTGAAGTGC CTGCACAGGC TGCAGAAGGG CCCAGGCTAC 
ACCTACAAGG AGCTGCTAGT GTGGTACTGC AACAACACCA ACACACACGG CCCCAAACGC 
ATCATCTGCG AGGGGCCCAA GAAGAAGGCC ATGTGGTTCC TGCTCACGCT GCTCTTCGCC 
TGCCTGGTGT GCTGGCAGTG GGGCGTCTTC ATCCAGACCT ACCTGAGCTG GGAGGTCAGC 
GTCTCGCTCT CCATGGGCTT CAAGACCATG AACTTCCCAG CAGTCACCGT CTGCAATTCC 
AGCCCCTTCC AGTACTCCAA GGTCAAGCAC TTGCTGAAGG ACTTGTACAA GCTGATGGAG 
GCTGTCCTGG ACAAGATTCT GGCTCCGAAG TCCAGCCACA CCAACACCAC CAGTACCCTG 
AACTTTACCA TCTGGAACCA CACGCCCCTG GTCCTTATTG ATGAGCGGAA CCCTGACCAT 
CCAGTGGTCC TCAACTTGTT TGGGGACAGC CACAACAGCA GCAACCCAGC CCCAGGAAGC 
ACCTGTAATG CCCAAGGGTG CAAAGTGGCC ATGAGGCTGT GCAGTGCCAA TGGGACCGTG 
TGTACCTTCC GAAACTTCAC CAGTGCCACC CAGGCCGTGA CTGAGTGGTA CATCCTGCAG 
GCCACCAACA TCTTCTCACA AGTGCTCCCC CAGGACCTGG TGGGGATGGG CTATGCTCCT 
GATCGCATAA TCCTAGCCTG TCTGTTTGGA ACGGAGCCCT GCAGTCATCG GAACTTCACA 
CCTATCTTCT ACCCTGATTA TGGCAACTGC TACATCTTCA ACTGGGGCAT GACAGAGAAG 
GCACTTCCTT CTGCCAACCC TGGGACTGAA TTTGGTCTCA AGTTGATCCT GGACATTGGT 
CAGGAGGACT ATGTCCCCTT CCTTGCGTCC ACAGCAGGGG CTAGGCTGAT GCTCCACGAG 
CAGAGGACAT ACCCCTTCAT TAGAGAAGAG GGCATCTATG CCATGGCAGG AACTGAGACT 
TCTATTGGGG TGCTGCTGGA CAAGCTGCAG GGCAAGGGGG AGCCATACAG TCCCTGCACC 
ATGAACGGCT CCGACGTTGC CATTCAGAAC CTCTACAGTG ACTACAACAC GACCTATTCC 
ATCCAGGCCT GCCTTCATTC CTGTTTCCAA GACCACATGA TCCATAACTG CAGCTGTGGT 
CACTACTTGT ACCCTTTGCC TGCTGGGGAG AAATACTGCA ACAACAGAGA CTTCCCAGAC 
TGGGCCTACT GCTACCTAAG CCTACAGATG AGTGTGGTCC AGAGAGAGAC CTGCCTCAGC 
ATGTGCAAGG AGTCCTGCAA CGACACCCAG TATAAGATGA CCATCTCCAT GGCTGACTGG 
CCATCCGAGG CCTCTGAGGA TTGGATCCTA CATGTCCTGT CTCAGGAGCG GGACCAGAGC 
TCAAATATCA CCCTGAGCAG GAAGGGTATT GTCAAGCTCA ATATCTACTT CCAAGAGTTC 
AACTACCGTA CCATCGAGGA ATCGCCGGCC AACAATATCG TGTGGCTGCT CTCTAACCTG 
GGTGGCCAGT TTGGCTTCTG GATGGGGGGC TCGGTGCTGT GCCTCATTGA GTTTGGGGAG 
ATCATTATCG ACTTCATTTG GATCACTGTC ATCAAGCTAG TGGCCTCCTG TAAAGGCCTG 
CGCAGGAGGC GGCCACAGCG ACCCTACACT GGCCCGCCGC CCACTGTGGC CGAGCTGGTG 
GAGGCCCACA CCAACTGTGT CTTCCAGCCT GACACAACCA GCTGCAGGCC CAATGCCGAG 
GTCTACCCTG ACCAACAGAC TCTGCCCATT CCGGGCACTC CACCTCCCAA CTATGACTCC 
CTGAGGCTGC AGCCGCTGGA CACCATGGAG TCTGACAGCG AGGTGGAGGC CATCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Scnn1b ( XM_008759684.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008757906.1 Rattus norvegicus sodium channel epithelial 1 beta subunit (Scnn1b), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa42953
Clone ID Related Accession (Same CDS sequence)	XM_008759684.2 , XM_008759682.2 , XM_008759683.2
Accession Version	XM_008759684.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1917bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	amiloride-sensitive sodium channel subunit beta isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008759684.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCAGTGA AGAAGTACCT GCTGAAGTGC CTGCACAGGC TGCAGAAGGG CCCAGGCTAC 
ACCTACAAGG AGCTGCTAGT GTGGTACTGC AACAACACCA ACACACACGG CCCCAAACGC 
ATCATCTGCG AGGGGCCCAA GAAGAAGGCC ATGTGGTTCC TGCTCACGCT GCTCTTCGCC 
TGCCTGGTGT GCTGGCAGTG GGGCGTCTTC ATCCAGACCT ACCTGAGCTG GGAGGTCAGC 
GTCTCGCTCT CCATGGGCTT CAAGACCATG AACTTCCCAG CAGTCACCGT CTGCAATTCC 
AGCCCCTTCC AGTACTCCAA GGTCAAGCAC TTGCTGAAGG ACTTGGACAA GCTGATGGAG 
GCTGTCCTGG ACAAGATTCT GGCTCCGGAG TCCAGCCACA CCAACACCAC CAGTACCCTG 
AACTTTACCA TCTGGAACCA CACGCCCCTG GTCCTTATTG ATGAGCGGAA CCCTGACCAT 
CCAGTGGTCC TCAACTTGTT TGGGGACAGC CACAACAGCA GCAACCCAGC CCCAGGAAGC 
ACCTGTAATG CCCAAGGGTG CAAAGTGGCC ATGAGGCTGT GCAGTGCCAA TGGGACCGTG 
TGTACCTTCC GAAACTTCAC CAGTGCCACC CAGGCCGTGA CTGAGTGGTA CATCCTGCAG 
GCCACCAACA TCTTCTCACA AGTGCTCCCC CAGGACCTGG TGGGGATGGG CTATGCTCCT 
GATCGCATAA TCCTAGCCTG TCTGTTTGGA ACGGAGCCCT GCAGTCATCG GAACTTCACA 
CCTATCTTCT ACCCTGATTA TGGCAACTGC TACATCTTCA ACTGGGGCAT GACAGAGAAG 
GCACTTCCTT CTGCCAACCC TGGGACTGAA TTTGGTCTCA AGTTGATCCT GGACATTGGT 
CAGGAGGACT ATGTCCCCTT CCTTGCGTCC ACAGCAGGGG CTAGGCTGAT GCTCCACGAG 
CAGAGGACAT ACCCCTTCAT TAGAGAAGAG GGCATCTATG CCATGGCAGG AACTGAGACT 
TCTATTGGGG TGCTGGTGGA CAAGCTGCAG CGCAAGGGGG AGCCATACAG TCCCTGCACC 
ATGAACGGCT CCGACGTTGC CATTCAGAAC CTCTACAGTG ACTACAACAC GACCTATTCC 
ATCCAGGCCT GCCTTCATTC CTGTTTCCAA GACCACATGA TCCATAACTG CAGCTGTGGT 
CACTACTTGT ACCCTTTGCC TGCTGGGGAG AAATACTGCA ACAACAGAGA CTTCCCAGAC 
TGGGCCTACT GCTACCTAAG CCTACAGATG AGTGTGGTCC AGAGAGAGAC CTGCCTCAGC 
ATGTGCAAGG AGTCCTGCAA CGACACCCAG TATAAGATGA CCATCTCCAT GGCTGACTGG 
CCATCCGAGG CCTCTGAGGA TTGGATCCTA CATGTCCTGT CTCAGGAGCG GGACCAGAGC 
TCAAATATCA CCCTGAGCAG GAAGGGTATT GTCAAGCTCA ATATCTACTT CCAAGAGTTC 
AACTACCGTA CCATCGAGGA ATCGCCGGCC AACAATATCG TGTGGCTGCT CTCTAACCTG 
GGTGGCCAGT TTGGCTTCTG GATGGGGGGC TCGGTGCTGT GCCTCATTGA GTTTGGGGAG 
ATCATTATCG ACTTCATTTG GATCACTGTC ATCAAGCTAG TGGCCTCCTG TAAAGGCCTG 
CGCAGGAGGC GGCCACAGGC ACCCTACACT GGCCCGCCGC CCACTGTGGC CGAGCTGGTG 
GAGGCCCACA CCAACTTTGG CTTCCAGCCT GACACAACCA GCTGCAGGCC CAATGCCGAG 
GTCTACCCTG ACCAACAGAC TCTGCCCATT CCGGGCACTC CACCTCCCAA CTATGACTCC 
CTGAGGCTGC AGCCGCTGGA CACCATGGAG TCTGACAGCG AGGTGGAGGC CATCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008757906.1
CDS	146..2062
Translation	MPVKKYLLKCLHRLQKGPGYTYKELLVWYCNNTNTHGPKRIICEGPKKKAMWFLLTLLFACLVCWQWGVFIQTYLSWEVSVSLSMGFKTMNFPAVTVCNSSPFQYSKVKHLLKDLDKLMEAVLDKILAPESSHTNTTSTLNFTIWNHTPLVLIDERNPDHPVVLNLFGDSHNSSNPAPGSTCNAQGCKVAMRLCSANGTVCTFRNFTSATQAVTEWYILQATNIFSQVLPQDLVGMGYAPDRIILACLFGTEPCSHRNFTPIFYPDYGNCYIFNWGMTEKALPSANPGTEFGLKLILDIGQEDYVPFLASTAGARLMLHEQRTYPFIREEGIYAMAGTETSIGVLVDKLQRKGEPYSPCTMNGSDVAIQNLYSDYNTTYSIQACLHSCFQDHMIHNCSCGHYLYPLPAGEKYCNNRDFPDWAYCYLSLQMSVVQRETCLSMCKESCNDTQYKMTISMADWPSEASEDWILHVLSQERDQSSNITLSRKGIVKLNIYFQEFNYRTIEESPANNIVWLLSNLGGQFGFWMGGSVLCLIEFGEIIIDFIWITVIKLVASCKGLRRRRPQAPYTGPPPTVAELVEAHTNFGFQPDTTSCRPNAEVYPDQQTLPIPGTPPPNYDSLRLQPLDTMESDSEVEAI

Target ORF information:

RefSeq Version	XM_008759684.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus sodium channel epithelial 1 beta subunit (Scnn1b), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008759684.2

ORF Insert Sequence:

ATGCCAGTGA AGAAGTACCT GCTGAAGTGC CTGCACAGGC TGCAGAAGGG CCCAGGCTAC 
ACCTACAAGG AGCTGCTAGT GTGGTACTGC AACAACACCA ACACACACGG CCCCAAACGC 
ATCATCTGCG AGGGGCCCAA GAAGAAGGCC ATGTGGTTCC TGCTCACGCT GCTCTTCGCC 
TGCCTGGTGT GCTGGCAGTG GGGCGTCTTC ATCCAGACCT ACCTGAGCTG GGAGGTCAGC 
GTCTCGCTCT CCATGGGCTT CAAGACCATG AACTTCCCAG CAGTCACCGT CTGCAATTCC 
AGCCCCTTCC AGTACTCCAA GGTCAAGCAC TTGCTGAAGG ACTTGGACAA GCTGATGGAG 
GCTGTCCTGG ACAAGATTCT GGCTCCGGAG TCCAGCCACA CCAACACCAC CAGTACCCTG 
AACTTTACCA TCTGGAACCA CACGCCCCTG GTCCTTATTG ATGAGCGGAA CCCTGACCAT 
CCAGTGGTCC TCAACTTGTT TGGGGACAGC CACAACAGCA GCAACCCAGC CCCAGGAAGC 
ACCTGTAATG CCCAAGGGTG CAAAGTGGCC ATGAGGCTGT GCAGTGCCAA TGGGACCGTG 
TGTACCTTCC GAAACTTCAC CAGTGCCACC CAGGCCGTGA CTGAGTGGTA CATCCTGCAG 
GCCACCAACA TCTTCTCACA AGTGCTCCCC CAGGACCTGG TGGGGATGGG CTATGCTCCT 
GATCGCATAA TCCTAGCCTG TCTGTTTGGA ACGGAGCCCT GCAGTCATCG GAACTTCACA 
CCTATCTTCT ACCCTGATTA TGGCAACTGC TACATCTTCA ACTGGGGCAT GACAGAGAAG 
GCACTTCCTT CTGCCAACCC TGGGACTGAA TTTGGTCTCA AGTTGATCCT GGACATTGGT 
CAGGAGGACT ATGTCCCCTT CCTTGCGTCC ACAGCAGGGG CTAGGCTGAT GCTCCACGAG 
CAGAGGACAT ACCCCTTCAT TAGAGAAGAG GGCATCTATG CCATGGCAGG AACTGAGACT 
TCTATTGGGG TGCTGGTGGA CAAGCTGCAG CGCAAGGGGG AGCCATACAG TCCCTGCACC 
ATGAACGGCT CCGACGTTGC CATTCAGAAC CTCTACAGTG ACTACAACAC GACCTATTCC 
ATCCAGGCCT GCCTTCATTC CTGTTTCCAA GACCACATGA TCCATAACTG CAGCTGTGGT 
CACTACTTGT ACCCTTTGCC TGCTGGGGAG AAATACTGCA ACAACAGAGA CTTCCCAGAC 
TGGGCCTACT GCTACCTAAG CCTACAGATG AGTGTGGTCC AGAGAGAGAC CTGCCTCAGC 
ATGTGCAAGG AGTCCTGCAA CGACACCCAG TATAAGATGA CCATCTCCAT GGCTGACTGG 
CCATCCGAGG CCTCTGAGGA TTGGATCCTA CATGTCCTGT CTCAGGAGCG GGACCAGAGC 
TCAAATATCA CCCTGAGCAG GAAGGGTATT GTCAAGCTCA ATATCTACTT CCAAGAGTTC 
AACTACCGTA CCATCGAGGA ATCGCCGGCC AACAATATCG TGTGGCTGCT CTCTAACCTG 
GGTGGCCAGT TTGGCTTCTG GATGGGGGGC TCGGTGCTGT GCCTCATTGA GTTTGGGGAG 
ATCATTATCG ACTTCATTTG GATCACTGTC ATCAAGCTAG TGGCCTCCTG TAAAGGCCTG 
CGCAGGAGGC GGCCACAGGC ACCCTACACT GGCCCGCCGC CCACTGTGGC CGAGCTGGTG 
GAGGCCCACA CCAACTTTGG CTTCCAGCCT GACACAACCA GCTGCAGGCC CAATGCCGAG 
GTCTACCCTG ACCAACAGAC TCTGCCCATT CCGGGCACTC CACCTCCCAA CTATGACTCC 
CTGAGGCTGC AGCCGCTGGA CACCATGGAG TCTGACAGCG AGGTGGAGGC CATCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Scnn1b ( XM_008759682.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008757904.1 Rattus norvegicus sodium channel epithelial 1 beta subunit (Scnn1b), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa42953
Clone ID Related Accession (Same CDS sequence)	XM_008759684.2 , XM_008759682.2 , XM_008759683.2
Accession Version	XM_008759682.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1917bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	amiloride-sensitive sodium channel subunit beta isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008759682.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCAGTGA AGAAGTACCT GCTGAAGTGC CTGCACAGGC TGCAGAAGGG CCCAGGCTAC 
ACCTACAAGG AGCTGCTAGT GTGGTACTGC AACAACACCA ACACACACGG CCCCAAACGC 
ATCATCTGCG AGGGGCCCAA GAAGAAGGCC ATGTGGTTCC TGCTCACGCT GCTCTTCGCC 
TGCCTGGTGT GCTGGCAGTG GGGCGTCTTC ATCCAGACCT ACCTGAGCTG GGAGGTCAGC 
GTCTCGCTCT CCATGGGCTT CAAGACCATG AACTTCCCAG CAGTCACCGT CTGCAATTCC 
AGCCCCTTCC AGTACTCCAA GGTCAAGCAC TTGCTGAAGG ACTTGGACAA GCTGATGGAG 
GCTGTCCTGG ACAAGATTCT GGCTCCGGAG TCCAGCCACA CCAACACCAC CAGTACCCTG 
AACTTTACCA TCTGGAACCA CACGCCCCTG GTCCTTATTG ATGAGCGGAA CCCTGACCAT 
CCAGTGGTCC TCAACTTGTT TGGGGACAGC CACAACAGCA GCAACCCAGC CCCAGGAAGC 
ACCTGTAATG CCCAAGGGTG CAAAGTGGCC ATGAGGCTGT GCAGTGCCAA TGGGACCGTG 
TGTACCTTCC GAAACTTCAC CAGTGCCACC CAGGCCGTGA CTGAGTGGTA CATCCTGCAG 
GCCACCAACA TCTTCTCACA AGTGCTCCCC CAGGACCTGG TGGGGATGGG CTATGCTCCT 
GATCGCATAA TCCTAGCCTG TCTGTTTGGA ACGGAGCCCT GCAGTCATCG GAACTTCACA 
CCTATCTTCT ACCCTGATTA TGGCAACTGC TACATCTTCA ACTGGGGCAT GACAGAGAAG 
GCACTTCCTT CTGCCAACCC TGGGACTGAA TTTGGTCTCA AGTTGATCCT GGACATTGGT 
CAGGAGGACT ATGTCCCCTT CCTTGCGTCC ACAGCAGGGG CTAGGCTGAT GCTCCACGAG 
CAGAGGACAT ACCCCTTCAT TAGAGAAGAG GGCATCTATG CCATGGCAGG AACTGAGACT 
TCTATTGGGG TGCTGGTGGA CAAGCTGCAG CGCAAGGGGG AGCCATACAG TCCCTGCACC 
ATGAACGGCT CCGACGTTGC CATTCAGAAC CTCTACAGTG ACTACAACAC GACCTATTCC 
ATCCAGGCCT GCCTTCATTC CTGTTTCCAA GACCACATGA TCCATAACTG CAGCTGTGGT 
CACTACTTGT ACCCTTTGCC TGCTGGGGAG AAATACTGCA ACAACAGAGA CTTCCCAGAC 
TGGGCCTACT GCTACCTAAG CCTACAGATG AGTGTGGTCC AGAGAGAGAC CTGCCTCAGC 
ATGTGCAAGG AGTCCTGCAA CGACACCCAG TATAAGATGA CCATCTCCAT GGCTGACTGG 
CCATCCGAGG CCTCTGAGGA TTGGATCCTA CATGTCCTGT CTCAGGAGCG GGACCAGAGC 
TCAAATATCA CCCTGAGCAG GAAGGGTATT GTCAAGCTCA ATATCTACTT CCAAGAGTTC 
AACTACCGTA CCATCGAGGA ATCGCCGGCC AACAATATCG TGTGGCTGCT CTCTAACCTG 
GGTGGCCAGT TTGGCTTCTG GATGGGGGGC TCGGTGCTGT GCCTCATTGA GTTTGGGGAG 
ATCATTATCG ACTTCATTTG GATCACTGTC ATCAAGCTAG TGGCCTCCTG TAAAGGCCTG 
CGCAGGAGGC GGCCACAGGC ACCCTACACT GGCCCGCCGC CCACTGTGGC CGAGCTGGTG 
GAGGCCCACA CCAACTTTGG CTTCCAGCCT GACACAACCA GCTGCAGGCC CAATGCCGAG 
GTCTACCCTG ACCAACAGAC TCTGCCCATT CCGGGCACTC CACCTCCCAA CTATGACTCC 
CTGAGGCTGC AGCCGCTGGA CACCATGGAG TCTGACAGCG AGGTGGAGGC CATCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008757904.1
CDS	90..2006
Translation	MPVKKYLLKCLHRLQKGPGYTYKELLVWYCNNTNTHGPKRIICEGPKKKAMWFLLTLLFACLVCWQWGVFIQTYLSWEVSVSLSMGFKTMNFPAVTVCNSSPFQYSKVKHLLKDLDKLMEAVLDKILAPESSHTNTTSTLNFTIWNHTPLVLIDERNPDHPVVLNLFGDSHNSSNPAPGSTCNAQGCKVAMRLCSANGTVCTFRNFTSATQAVTEWYILQATNIFSQVLPQDLVGMGYAPDRIILACLFGTEPCSHRNFTPIFYPDYGNCYIFNWGMTEKALPSANPGTEFGLKLILDIGQEDYVPFLASTAGARLMLHEQRTYPFIREEGIYAMAGTETSIGVLVDKLQRKGEPYSPCTMNGSDVAIQNLYSDYNTTYSIQACLHSCFQDHMIHNCSCGHYLYPLPAGEKYCNNRDFPDWAYCYLSLQMSVVQRETCLSMCKESCNDTQYKMTISMADWPSEASEDWILHVLSQERDQSSNITLSRKGIVKLNIYFQEFNYRTIEESPANNIVWLLSNLGGQFGFWMGGSVLCLIEFGEIIIDFIWITVIKLVASCKGLRRRRPQAPYTGPPPTVAELVEAHTNFGFQPDTTSCRPNAEVYPDQQTLPIPGTPPPNYDSLRLQPLDTMESDSEVEAI

Target ORF information:

RefSeq Version	XM_008759682.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus sodium channel epithelial 1 beta subunit (Scnn1b), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008759682.2

ORF Insert Sequence:

ATGCCAGTGA AGAAGTACCT GCTGAAGTGC CTGCACAGGC TGCAGAAGGG CCCAGGCTAC 
ACCTACAAGG AGCTGCTAGT GTGGTACTGC AACAACACCA ACACACACGG CCCCAAACGC 
ATCATCTGCG AGGGGCCCAA GAAGAAGGCC ATGTGGTTCC TGCTCACGCT GCTCTTCGCC 
TGCCTGGTGT GCTGGCAGTG GGGCGTCTTC ATCCAGACCT ACCTGAGCTG GGAGGTCAGC 
GTCTCGCTCT CCATGGGCTT CAAGACCATG AACTTCCCAG CAGTCACCGT CTGCAATTCC 
AGCCCCTTCC AGTACTCCAA GGTCAAGCAC TTGCTGAAGG ACTTGGACAA GCTGATGGAG 
GCTGTCCTGG ACAAGATTCT GGCTCCGGAG TCCAGCCACA CCAACACCAC CAGTACCCTG 
AACTTTACCA TCTGGAACCA CACGCCCCTG GTCCTTATTG ATGAGCGGAA CCCTGACCAT 
CCAGTGGTCC TCAACTTGTT TGGGGACAGC CACAACAGCA GCAACCCAGC CCCAGGAAGC 
ACCTGTAATG CCCAAGGGTG CAAAGTGGCC ATGAGGCTGT GCAGTGCCAA TGGGACCGTG 
TGTACCTTCC GAAACTTCAC CAGTGCCACC CAGGCCGTGA CTGAGTGGTA CATCCTGCAG 
GCCACCAACA TCTTCTCACA AGTGCTCCCC CAGGACCTGG TGGGGATGGG CTATGCTCCT 
GATCGCATAA TCCTAGCCTG TCTGTTTGGA ACGGAGCCCT GCAGTCATCG GAACTTCACA 
CCTATCTTCT ACCCTGATTA TGGCAACTGC TACATCTTCA ACTGGGGCAT GACAGAGAAG 
GCACTTCCTT CTGCCAACCC TGGGACTGAA TTTGGTCTCA AGTTGATCCT GGACATTGGT 
CAGGAGGACT ATGTCCCCTT CCTTGCGTCC ACAGCAGGGG CTAGGCTGAT GCTCCACGAG 
CAGAGGACAT ACCCCTTCAT TAGAGAAGAG GGCATCTATG CCATGGCAGG AACTGAGACT 
TCTATTGGGG TGCTGGTGGA CAAGCTGCAG CGCAAGGGGG AGCCATACAG TCCCTGCACC 
ATGAACGGCT CCGACGTTGC CATTCAGAAC CTCTACAGTG ACTACAACAC GACCTATTCC 
ATCCAGGCCT GCCTTCATTC CTGTTTCCAA GACCACATGA TCCATAACTG CAGCTGTGGT 
CACTACTTGT ACCCTTTGCC TGCTGGGGAG AAATACTGCA ACAACAGAGA CTTCCCAGAC 
TGGGCCTACT GCTACCTAAG CCTACAGATG AGTGTGGTCC AGAGAGAGAC CTGCCTCAGC 
ATGTGCAAGG AGTCCTGCAA CGACACCCAG TATAAGATGA CCATCTCCAT GGCTGACTGG 
CCATCCGAGG CCTCTGAGGA TTGGATCCTA CATGTCCTGT CTCAGGAGCG GGACCAGAGC 
TCAAATATCA CCCTGAGCAG GAAGGGTATT GTCAAGCTCA ATATCTACTT CCAAGAGTTC 
AACTACCGTA CCATCGAGGA ATCGCCGGCC AACAATATCG TGTGGCTGCT CTCTAACCTG 
GGTGGCCAGT TTGGCTTCTG GATGGGGGGC TCGGTGCTGT GCCTCATTGA GTTTGGGGAG 
ATCATTATCG ACTTCATTTG GATCACTGTC ATCAAGCTAG TGGCCTCCTG TAAAGGCCTG 
CGCAGGAGGC GGCCACAGGC ACCCTACACT GGCCCGCCGC CCACTGTGGC CGAGCTGGTG 
GAGGCCCACA CCAACTTTGG CTTCCAGCCT GACACAACCA GCTGCAGGCC CAATGCCGAG 
GTCTACCCTG ACCAACAGAC TCTGCCCATT CCGGGCACTC CACCTCCCAA CTATGACTCC 
CTGAGGCTGC AGCCGCTGGA CACCATGGAG TCTGACAGCG AGGTGGAGGC CATCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Scnn1b ( XM_008759683.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008757905.1 Rattus norvegicus sodium channel epithelial 1 beta subunit (Scnn1b), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa42953
Clone ID Related Accession (Same CDS sequence)	XM_008759684.2 , XM_008759682.2 , XM_008759683.2
Accession Version	XM_008759683.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1917bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	amiloride-sensitive sodium channel subunit beta isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008759683.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCAGTGA AGAAGTACCT GCTGAAGTGC CTGCACAGGC TGCAGAAGGG CCCAGGCTAC 
ACCTACAAGG AGCTGCTAGT GTGGTACTGC AACAACACCA ACACACACGG CCCCAAACGC 
ATCATCTGCG AGGGGCCCAA GAAGAAGGCC ATGTGGTTCC TGCTCACGCT GCTCTTCGCC 
TGCCTGGTGT GCTGGCAGTG GGGCGTCTTC ATCCAGACCT ACCTGAGCTG GGAGGTCAGC 
GTCTCGCTCT CCATGGGCTT CAAGACCATG AACTTCCCAG CAGTCACCGT CTGCAATTCC 
AGCCCCTTCC AGTACTCCAA GGTCAAGCAC TTGCTGAAGG ACTTGGACAA GCTGATGGAG 
GCTGTCCTGG ACAAGATTCT GGCTCCGGAG TCCAGCCACA CCAACACCAC CAGTACCCTG 
AACTTTACCA TCTGGAACCA CACGCCCCTG GTCCTTATTG ATGAGCGGAA CCCTGACCAT 
CCAGTGGTCC TCAACTTGTT TGGGGACAGC CACAACAGCA GCAACCCAGC CCCAGGAAGC 
ACCTGTAATG CCCAAGGGTG CAAAGTGGCC ATGAGGCTGT GCAGTGCCAA TGGGACCGTG 
TGTACCTTCC GAAACTTCAC CAGTGCCACC CAGGCCGTGA CTGAGTGGTA CATCCTGCAG 
GCCACCAACA TCTTCTCACA AGTGCTCCCC CAGGACCTGG TGGGGATGGG CTATGCTCCT 
GATCGCATAA TCCTAGCCTG TCTGTTTGGA ACGGAGCCCT GCAGTCATCG GAACTTCACA 
CCTATCTTCT ACCCTGATTA TGGCAACTGC TACATCTTCA ACTGGGGCAT GACAGAGAAG 
GCACTTCCTT CTGCCAACCC TGGGACTGAA TTTGGTCTCA AGTTGATCCT GGACATTGGT 
CAGGAGGACT ATGTCCCCTT CCTTGCGTCC ACAGCAGGGG CTAGGCTGAT GCTCCACGAG 
CAGAGGACAT ACCCCTTCAT TAGAGAAGAG GGCATCTATG CCATGGCAGG AACTGAGACT 
TCTATTGGGG TGCTGGTGGA CAAGCTGCAG CGCAAGGGGG AGCCATACAG TCCCTGCACC 
ATGAACGGCT CCGACGTTGC CATTCAGAAC CTCTACAGTG ACTACAACAC GACCTATTCC 
ATCCAGGCCT GCCTTCATTC CTGTTTCCAA GACCACATGA TCCATAACTG CAGCTGTGGT 
CACTACTTGT ACCCTTTGCC TGCTGGGGAG AAATACTGCA ACAACAGAGA CTTCCCAGAC 
TGGGCCTACT GCTACCTAAG CCTACAGATG AGTGTGGTCC AGAGAGAGAC CTGCCTCAGC 
ATGTGCAAGG AGTCCTGCAA CGACACCCAG TATAAGATGA CCATCTCCAT GGCTGACTGG 
CCATCCGAGG CCTCTGAGGA TTGGATCCTA CATGTCCTGT CTCAGGAGCG GGACCAGAGC 
TCAAATATCA CCCTGAGCAG GAAGGGTATT GTCAAGCTCA ATATCTACTT CCAAGAGTTC 
AACTACCGTA CCATCGAGGA ATCGCCGGCC AACAATATCG TGTGGCTGCT CTCTAACCTG 
GGTGGCCAGT TTGGCTTCTG GATGGGGGGC TCGGTGCTGT GCCTCATTGA GTTTGGGGAG 
ATCATTATCG ACTTCATTTG GATCACTGTC ATCAAGCTAG TGGCCTCCTG TAAAGGCCTG 
CGCAGGAGGC GGCCACAGGC ACCCTACACT GGCCCGCCGC CCACTGTGGC CGAGCTGGTG 
GAGGCCCACA CCAACTTTGG CTTCCAGCCT GACACAACCA GCTGCAGGCC CAATGCCGAG 
GTCTACCCTG ACCAACAGAC TCTGCCCATT CCGGGCACTC CACCTCCCAA CTATGACTCC 
CTGAGGCTGC AGCCGCTGGA CACCATGGAG TCTGACAGCG AGGTGGAGGC CATCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008757905.1
CDS	300..2216
Translation	MPVKKYLLKCLHRLQKGPGYTYKELLVWYCNNTNTHGPKRIICEGPKKKAMWFLLTLLFACLVCWQWGVFIQTYLSWEVSVSLSMGFKTMNFPAVTVCNSSPFQYSKVKHLLKDLDKLMEAVLDKILAPESSHTNTTSTLNFTIWNHTPLVLIDERNPDHPVVLNLFGDSHNSSNPAPGSTCNAQGCKVAMRLCSANGTVCTFRNFTSATQAVTEWYILQATNIFSQVLPQDLVGMGYAPDRIILACLFGTEPCSHRNFTPIFYPDYGNCYIFNWGMTEKALPSANPGTEFGLKLILDIGQEDYVPFLASTAGARLMLHEQRTYPFIREEGIYAMAGTETSIGVLVDKLQRKGEPYSPCTMNGSDVAIQNLYSDYNTTYSIQACLHSCFQDHMIHNCSCGHYLYPLPAGEKYCNNRDFPDWAYCYLSLQMSVVQRETCLSMCKESCNDTQYKMTISMADWPSEASEDWILHVLSQERDQSSNITLSRKGIVKLNIYFQEFNYRTIEESPANNIVWLLSNLGGQFGFWMGGSVLCLIEFGEIIIDFIWITVIKLVASCKGLRRRRPQAPYTGPPPTVAELVEAHTNFGFQPDTTSCRPNAEVYPDQQTLPIPGTPPPNYDSLRLQPLDTMESDSEVEAI

Target ORF information:

RefSeq Version	XM_008759683.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus sodium channel epithelial 1 beta subunit (Scnn1b), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008759683.2

ORF Insert Sequence:

ATGCCAGTGA AGAAGTACCT GCTGAAGTGC CTGCACAGGC TGCAGAAGGG CCCAGGCTAC 
ACCTACAAGG AGCTGCTAGT GTGGTACTGC AACAACACCA ACACACACGG CCCCAAACGC 
ATCATCTGCG AGGGGCCCAA GAAGAAGGCC ATGTGGTTCC TGCTCACGCT GCTCTTCGCC 
TGCCTGGTGT GCTGGCAGTG GGGCGTCTTC ATCCAGACCT ACCTGAGCTG GGAGGTCAGC 
GTCTCGCTCT CCATGGGCTT CAAGACCATG AACTTCCCAG CAGTCACCGT CTGCAATTCC 
AGCCCCTTCC AGTACTCCAA GGTCAAGCAC TTGCTGAAGG ACTTGGACAA GCTGATGGAG 
GCTGTCCTGG ACAAGATTCT GGCTCCGGAG TCCAGCCACA CCAACACCAC CAGTACCCTG 
AACTTTACCA TCTGGAACCA CACGCCCCTG GTCCTTATTG ATGAGCGGAA CCCTGACCAT 
CCAGTGGTCC TCAACTTGTT TGGGGACAGC CACAACAGCA GCAACCCAGC CCCAGGAAGC 
ACCTGTAATG CCCAAGGGTG CAAAGTGGCC ATGAGGCTGT GCAGTGCCAA TGGGACCGTG 
TGTACCTTCC GAAACTTCAC CAGTGCCACC CAGGCCGTGA CTGAGTGGTA CATCCTGCAG 
GCCACCAACA TCTTCTCACA AGTGCTCCCC CAGGACCTGG TGGGGATGGG CTATGCTCCT 
GATCGCATAA TCCTAGCCTG TCTGTTTGGA ACGGAGCCCT GCAGTCATCG GAACTTCACA 
CCTATCTTCT ACCCTGATTA TGGCAACTGC TACATCTTCA ACTGGGGCAT GACAGAGAAG 
GCACTTCCTT CTGCCAACCC TGGGACTGAA TTTGGTCTCA AGTTGATCCT GGACATTGGT 
CAGGAGGACT ATGTCCCCTT CCTTGCGTCC ACAGCAGGGG CTAGGCTGAT GCTCCACGAG 
CAGAGGACAT ACCCCTTCAT TAGAGAAGAG GGCATCTATG CCATGGCAGG AACTGAGACT 
TCTATTGGGG TGCTGGTGGA CAAGCTGCAG CGCAAGGGGG AGCCATACAG TCCCTGCACC 
ATGAACGGCT CCGACGTTGC CATTCAGAAC CTCTACAGTG ACTACAACAC GACCTATTCC 
ATCCAGGCCT GCCTTCATTC CTGTTTCCAA GACCACATGA TCCATAACTG CAGCTGTGGT 
CACTACTTGT ACCCTTTGCC TGCTGGGGAG AAATACTGCA ACAACAGAGA CTTCCCAGAC 
TGGGCCTACT GCTACCTAAG CCTACAGATG AGTGTGGTCC AGAGAGAGAC CTGCCTCAGC 
ATGTGCAAGG AGTCCTGCAA CGACACCCAG TATAAGATGA CCATCTCCAT GGCTGACTGG 
CCATCCGAGG CCTCTGAGGA TTGGATCCTA CATGTCCTGT CTCAGGAGCG GGACCAGAGC 
TCAAATATCA CCCTGAGCAG GAAGGGTATT GTCAAGCTCA ATATCTACTT CCAAGAGTTC 
AACTACCGTA CCATCGAGGA ATCGCCGGCC AACAATATCG TGTGGCTGCT CTCTAACCTG 
GGTGGCCAGT TTGGCTTCTG GATGGGGGGC TCGGTGCTGT GCCTCATTGA GTTTGGGGAG 
ATCATTATCG ACTTCATTTG GATCACTGTC ATCAAGCTAG TGGCCTCCTG TAAAGGCCTG 
CGCAGGAGGC GGCCACAGGC ACCCTACACT GGCCCGCCGC CCACTGTGGC CGAGCTGGTG 
GAGGCCCACA CCAACTTTGG CTTCCAGCCT GACACAACCA GCTGCAGGCC CAATGCCGAG 
GTCTACCCTG ACCAACAGAC TCTGCCCATT CCGGGCACTC CACCTCCCAA CTATGACTCC 
CTGAGGCTGC AGCCGCTGGA CACCATGGAG TCTGACAGCG AGGTGGAGGC CATCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Scnn1b ( XM_008759685.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008757907.1 Rattus norvegicus sodium channel epithelial 1 beta subunit (Scnn1b), transcript variant X4, mRNA.

Price & Availability↑

CloneID	ORa42954
Clone ID Related Accession (Same CDS sequence)	XM_008759685.2
Accession Version	XM_008759685.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1590bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	amiloride-sensitive sodium channel subunit beta isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008759685.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCAGTGA AGAAGTACCT GCTGAAGTGC CTGCACAGGC TGCAGAAGGG CCCAGGCTAC 
ACCTACAAGG AGCTGCTAGT GTGGTACTGC AACAACACCA ACACACACGG CCCCAAACGC 
ATCATCTGCG AGGGGCCCAA GAAGAAGGCC ATGTGGTTCC TGCTCACGCT GCTCTTCGCC 
TGCCTGGTGT GCTGGCAGTG GGGCGTCTTC ATCCAGACCT ACCTGAGCTG GGAGGTCAGC 
GTCTCGCTCT CCATGGGCTT CAAGACCATG AACTTCCCAG CAGTCACCGT CTGCAATTCC 
AGCCCCTTCC AGTACTCCAA GGTCAAGCAC TTGCTGAAGG ACTTGGACAA GCTGATGGAG 
GCTGTCCTGG ACAAGATTCT GGCTCCGGAG TCCAGCCACA CCAACACCAC CAGTACCCTG 
AACTTTACCA TCTGGAACCA CACGCCCCTG GTCCTTATTG ATGAGCGGAA CCCTGACCAT 
CCAGTGGTCC TCAACTTGTT TGGGGACAGC CACAACAGCA GCAACCCAGC CCCAGGAAGC 
ACCTGTAATG CCCAAGGGTG CAAAGTGGCC ATGAGGCTGT GCAGTGCCAA TGGGACCGTG 
TGTACCTTCC GAAACTTCAC CAGTGCCACC CAGGCCGTGA CTGAGTGGTA CATCCTGCAG 
GCCACCAACA TCTTCTCACA AGTGCTCCCC CAGGACCTGG TGGGGATGGG CTATGCTCCT 
GATCGCATAA TCCTAGCCTG TCTGTTTGGA ACGGAGCCCT GCAGTCATCG GAACTTCACA 
CCTATCTTCT ACCCTGATTA TGGCAACTGC TACATCTTCA ACTGGGGCAT GACAGAGAAG 
GCACTTCCTT CTGCCAACCC TGGGACTGAA TTTGGTCTCA AGTTGATCCT GGACATTGGT 
CAGGAGGACT ATGTCCCCTT CCTTGCGTCC ACAGCAGGGG CTAGGCTGAT GCTCCACGAG 
CAGAGGACAT ACCCCTTCAT TAGAGAAGAG GGCATCTATG CCATGGCAGG AACTGAGACT 
TCTATTGGGG TGCTGGTGGA CAAGCTGCAG CGCAAGGGGG AGCCATACAG TCCCTGCACC 
ATGAACGGCT CCGACGTTGC CATTCAGAAC CTCTACAGTG ACTACAACAC GACCTATTCC 
ATCCAGGCCT GCCTTCATTC CTGTTTCCAA GACCACATGA TCCATAACTG CAGCTGTGGT 
CACTACTTGT ACCCTTTGCC TGCTGGGGAG AAATACTGCA ACAACAGAGA CTTCCCAGAC 
TGGGCCTACT GCTACCTAAG CCTACAGATG AGTGTGGTCC AGAGAGAGAC CTGCCTCAGC 
ATGTGCAAGG AGTCCTGCAA CGACACCCAG TATAAGATGA CCATCTCCAT GGCTGACTGG 
CCATCCGAGG CCTCTGAGCT GCCTTCTTGG GTTCTAGGAT TGGATCCTAC ATGTCCTGTC 
TCAGGAGCGG GACCAGAGCT CAAATATCAC CCTGAGCAGG AAGGGTATTG TCAAGCTCAA 
TATCTACTTC CAAGAGTTCA ACTACCGTAC CATCGAGGAA TCGCCGGCCA ACAATGTAAG 
TGTGGGTGTG CCTGTCTTGT GGATCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008757907.1
CDS	96..1685
Translation	MPVKKYLLKCLHRLQKGPGYTYKELLVWYCNNTNTHGPKRIICEGPKKKAMWFLLTLLFACLVCWQWGVFIQTYLSWEVSVSLSMGFKTMNFPAVTVCNSSPFQYSKVKHLLKDLDKLMEAVLDKILAPESSHTNTTSTLNFTIWNHTPLVLIDERNPDHPVVLNLFGDSHNSSNPAPGSTCNAQGCKVAMRLCSANGTVCTFRNFTSATQAVTEWYILQATNIFSQVLPQDLVGMGYAPDRIILACLFGTEPCSHRNFTPIFYPDYGNCYIFNWGMTEKALPSANPGTEFGLKLILDIGQEDYVPFLASTAGARLMLHEQRTYPFIREEGIYAMAGTETSIGVLVDKLQRKGEPYSPCTMNGSDVAIQNLYSDYNTTYSIQACLHSCFQDHMIHNCSCGHYLYPLPAGEKYCNNRDFPDWAYCYLSLQMSVVQRETCLSMCKESCNDTQYKMTISMADWPSEASELPSWVLGLDPTCPVSGAGPELKYHPEQEGYCQAQYLLPRVQLPYHRGIAGQQCKCGCACLVDP

Target ORF information:

RefSeq Version	XM_008759685.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus sodium channel epithelial 1 beta subunit (Scnn1b), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008759685.2

ORF Insert Sequence:

ATGCCAGTGA AGAAGTACCT GCTGAAGTGC CTGCACAGGC TGCAGAAGGG CCCAGGCTAC 
ACCTACAAGG AGCTGCTAGT GTGGTACTGC AACAACACCA ACACACACGG CCCCAAACGC 
ATCATCTGCG AGGGGCCCAA GAAGAAGGCC ATGTGGTTCC TGCTCACGCT GCTCTTCGCC 
TGCCTGGTGT GCTGGCAGTG GGGCGTCTTC ATCCAGACCT ACCTGAGCTG GGAGGTCAGC 
GTCTCGCTCT CCATGGGCTT CAAGACCATG AACTTCCCAG CAGTCACCGT CTGCAATTCC 
AGCCCCTTCC AGTACTCCAA GGTCAAGCAC TTGCTGAAGG ACTTGGACAA GCTGATGGAG 
GCTGTCCTGG ACAAGATTCT GGCTCCGGAG TCCAGCCACA CCAACACCAC CAGTACCCTG 
AACTTTACCA TCTGGAACCA CACGCCCCTG GTCCTTATTG ATGAGCGGAA CCCTGACCAT 
CCAGTGGTCC TCAACTTGTT TGGGGACAGC CACAACAGCA GCAACCCAGC CCCAGGAAGC 
ACCTGTAATG CCCAAGGGTG CAAAGTGGCC ATGAGGCTGT GCAGTGCCAA TGGGACCGTG 
TGTACCTTCC GAAACTTCAC CAGTGCCACC CAGGCCGTGA CTGAGTGGTA CATCCTGCAG 
GCCACCAACA TCTTCTCACA AGTGCTCCCC CAGGACCTGG TGGGGATGGG CTATGCTCCT 
GATCGCATAA TCCTAGCCTG TCTGTTTGGA ACGGAGCCCT GCAGTCATCG GAACTTCACA 
CCTATCTTCT ACCCTGATTA TGGCAACTGC TACATCTTCA ACTGGGGCAT GACAGAGAAG 
GCACTTCCTT CTGCCAACCC TGGGACTGAA TTTGGTCTCA AGTTGATCCT GGACATTGGT 
CAGGAGGACT ATGTCCCCTT CCTTGCGTCC ACAGCAGGGG CTAGGCTGAT GCTCCACGAG 
CAGAGGACAT ACCCCTTCAT TAGAGAAGAG GGCATCTATG CCATGGCAGG AACTGAGACT 
TCTATTGGGG TGCTGGTGGA CAAGCTGCAG CGCAAGGGGG AGCCATACAG TCCCTGCACC 
ATGAACGGCT CCGACGTTGC CATTCAGAAC CTCTACAGTG ACTACAACAC GACCTATTCC 
ATCCAGGCCT GCCTTCATTC CTGTTTCCAA GACCACATGA TCCATAACTG CAGCTGTGGT 
CACTACTTGT ACCCTTTGCC TGCTGGGGAG AAATACTGCA ACAACAGAGA CTTCCCAGAC 
TGGGCCTACT GCTACCTAAG CCTACAGATG AGTGTGGTCC AGAGAGAGAC CTGCCTCAGC 
ATGTGCAAGG AGTCCTGCAA CGACACCCAG TATAAGATGA CCATCTCCAT GGCTGACTGG 
CCATCCGAGG CCTCTGAGCT GCCTTCTTGG GTTCTAGGAT TGGATCCTAC ATGTCCTGTC 
TCAGGAGCGG GACCAGAGCT CAAATATCAC CCTGAGCAGG AAGGGTATTG TCAAGCTCAA 
TATCTACTTC CAAGAGTTCA ACTACCGTAC CATCGAGGAA TCGCCGGCCA ACAATGTAAG 
TGTGGGTGTG CCTGTCTTGT GGATCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Scnn1b ( XM_008759686.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008757908.1 Rattus norvegicus sodium channel epithelial 1 beta subunit (Scnn1b), transcript variant X5, mRNA.

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CloneID	ORa42955
Clone ID Related Accession (Same CDS sequence)	XM_008759686.2
Accession Version	XM_008759686.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1575bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	amiloride-sensitive sodium channel subunit beta isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008759686.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCAGTGA AGAAGTACCT GCTGAAGTGC CTGCACAGGC TGCAGAAGGG CCCAGGCTAC 
ACCTACAAGG AGCTGCTAGT GTGGTACTGC AACAACACCA ACACACACGG CCCCAAACGC 
ATCATCTGCG AGGGGCCCAA GAAGAAGGCC ATGTGGTTCC TGCTCACGCT GCTCTTCGCC 
TGCCTGGTGT GCTGGCAGTG GGGCGTCTTC ATCCAGACCT ACCTGAGCTG GGAGGTCAGC 
GTCTCGCTCT CCATGGGCTT CAAGACCATG AACTTCCCAG CAGTCACCGT CTGCAATTCC 
AGCCCCTTCC AGTACTCCAA GGTCAAGCAC TTGCTGAAGG ACTTGGACAA GCTGATGGAG 
GCTGTCCTGG ACAAGATTCT GGCTCCGGAG TCCAGCCACA CCAACACCAC CAGTACCCTG 
AACTTTACCA TCTGGAACCA CACGCCCCTG GTCCTTATTG ATGAGCGGAA CCCTGACCAT 
CCAGTGGTCC TCAACTTGTT TGGGGACAGC CACAACAGCA GCAACCCAGC CCCAGGAAGC 
ACCTGTAATG CCCAAGGGTG CAAAGTGGCC ATGAGGCTGT GCAGTGCCAA TGGGACCGTG 
TGTACCTTCC GAAACTTCAC CAGTGCCACC CAGGCCGTGA CTGAGTGGTA CATCCTGCAG 
GCCACCAACA TCTTCTCACA AGTGCTCCCC CAGGACCTGG TGGGGATGGG CTATGCTCCT 
GATCGCATAA TCCTAGCCTG TCTGTTTGGA ACGGAGCCCT GCAGTCATCG GAACTTCACA 
CCTATCTTCT ACCCTGATTA TGGCAACTGC TACATCTTCA ACTGGGGCAT GACAGAGAAG 
GCACTTCCTT CTGCCAACCC TGGGACTGAA TTTGGTCTCA AGTTGATCCT GGACATTGGT 
CAGGAGGACT ATGTCCCCTT CCTTGCGTCC ACAGCAGGGG CTAGGCTGAT GCTCCACGAG 
CAGAGGACAT ACCCCTTCAT TAGAGAAGAG GGCATCTATG CCATGGCAGG AACTGAGACT 
TCTATTGGGG TGCTGGTGGA CAAGCTGCAG CGCAAGGGGG AGCCATACAG TCCCTGCACC 
ATGAACGGCT CCGACGTTGC CATTCAGAAC CTCTACAGTG ACTACAACAC GACCTATTCC 
ATCCAGGCCT GCCTTCATTC CTGTTTCCAA GACCACATGA TCCATAACTG CAGCTGTGGT 
CACTACTTGT ACCCTTTGCC TGCTGGGGAG AAATACTGCA ACAACAGAGA CTTCCCAGAC 
TGGGCCTACT GCTACCTAAG CCTACAGATG AGTGTGGTCC AGAGAGAGAC CTGCCTCAGC 
ATGTGCAAGG AGTCCTGCAA CGACACCCAG TATAAGATGA CCATCTCCAT GGCTGACTGG 
CCATCCGAGG CCTCTGAGCT GCCTTCTTGG GTTCTAGGAT TGGATCCTAC ATGTCCTGTC 
TCAGGAGCGG GACCAGAGCT CAAATATCAC CCTGAGCAGG AAGGGTATTG TCAAGCTCAA 
TATCTACTTC CAAGAGTTCA ACTACCGTAC CATCGAGGAA TCGCCGGCCA ACAATATCGT 
GTGGCTGCTC TCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008757908.1
CDS	95..1669
Translation	MPVKKYLLKCLHRLQKGPGYTYKELLVWYCNNTNTHGPKRIICEGPKKKAMWFLLTLLFACLVCWQWGVFIQTYLSWEVSVSLSMGFKTMNFPAVTVCNSSPFQYSKVKHLLKDLDKLMEAVLDKILAPESSHTNTTSTLNFTIWNHTPLVLIDERNPDHPVVLNLFGDSHNSSNPAPGSTCNAQGCKVAMRLCSANGTVCTFRNFTSATQAVTEWYILQATNIFSQVLPQDLVGMGYAPDRIILACLFGTEPCSHRNFTPIFYPDYGNCYIFNWGMTEKALPSANPGTEFGLKLILDIGQEDYVPFLASTAGARLMLHEQRTYPFIREEGIYAMAGTETSIGVLVDKLQRKGEPYSPCTMNGSDVAIQNLYSDYNTTYSIQACLHSCFQDHMIHNCSCGHYLYPLPAGEKYCNNRDFPDWAYCYLSLQMSVVQRETCLSMCKESCNDTQYKMTISMADWPSEASELPSWVLGLDPTCPVSGAGPELKYHPEQEGYCQAQYLLPRVQLPYHRGIAGQQYRVAAL

Target ORF information:

RefSeq Version	XM_008759686.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus sodium channel epithelial 1 beta subunit (Scnn1b), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008759686.2

ORF Insert Sequence:

ATGCCAGTGA AGAAGTACCT GCTGAAGTGC CTGCACAGGC TGCAGAAGGG CCCAGGCTAC 
ACCTACAAGG AGCTGCTAGT GTGGTACTGC AACAACACCA ACACACACGG CCCCAAACGC 
ATCATCTGCG AGGGGCCCAA GAAGAAGGCC ATGTGGTTCC TGCTCACGCT GCTCTTCGCC 
TGCCTGGTGT GCTGGCAGTG GGGCGTCTTC ATCCAGACCT ACCTGAGCTG GGAGGTCAGC 
GTCTCGCTCT CCATGGGCTT CAAGACCATG AACTTCCCAG CAGTCACCGT CTGCAATTCC 
AGCCCCTTCC AGTACTCCAA GGTCAAGCAC TTGCTGAAGG ACTTGGACAA GCTGATGGAG 
GCTGTCCTGG ACAAGATTCT GGCTCCGGAG TCCAGCCACA CCAACACCAC CAGTACCCTG 
AACTTTACCA TCTGGAACCA CACGCCCCTG GTCCTTATTG ATGAGCGGAA CCCTGACCAT 
CCAGTGGTCC TCAACTTGTT TGGGGACAGC CACAACAGCA GCAACCCAGC CCCAGGAAGC 
ACCTGTAATG CCCAAGGGTG CAAAGTGGCC ATGAGGCTGT GCAGTGCCAA TGGGACCGTG 
TGTACCTTCC GAAACTTCAC CAGTGCCACC CAGGCCGTGA CTGAGTGGTA CATCCTGCAG 
GCCACCAACA TCTTCTCACA AGTGCTCCCC CAGGACCTGG TGGGGATGGG CTATGCTCCT 
GATCGCATAA TCCTAGCCTG TCTGTTTGGA ACGGAGCCCT GCAGTCATCG GAACTTCACA 
CCTATCTTCT ACCCTGATTA TGGCAACTGC TACATCTTCA ACTGGGGCAT GACAGAGAAG 
GCACTTCCTT CTGCCAACCC TGGGACTGAA TTTGGTCTCA AGTTGATCCT GGACATTGGT 
CAGGAGGACT ATGTCCCCTT CCTTGCGTCC ACAGCAGGGG CTAGGCTGAT GCTCCACGAG 
CAGAGGACAT ACCCCTTCAT TAGAGAAGAG GGCATCTATG CCATGGCAGG AACTGAGACT 
TCTATTGGGG TGCTGGTGGA CAAGCTGCAG CGCAAGGGGG AGCCATACAG TCCCTGCACC 
ATGAACGGCT CCGACGTTGC CATTCAGAAC CTCTACAGTG ACTACAACAC GACCTATTCC 
ATCCAGGCCT GCCTTCATTC CTGTTTCCAA GACCACATGA TCCATAACTG CAGCTGTGGT 
CACTACTTGT ACCCTTTGCC TGCTGGGGAG AAATACTGCA ACAACAGAGA CTTCCCAGAC 
TGGGCCTACT GCTACCTAAG CCTACAGATG AGTGTGGTCC AGAGAGAGAC CTGCCTCAGC 
ATGTGCAAGG AGTCCTGCAA CGACACCCAG TATAAGATGA CCATCTCCAT GGCTGACTGG 
CCATCCGAGG CCTCTGAGCT GCCTTCTTGG GTTCTAGGAT TGGATCCTAC ATGTCCTGTC 
TCAGGAGCGG GACCAGAGCT CAAATATCAC CCTGAGCAGG AAGGGTATTG TCAAGCTCAA 
TATCTACTTC CAAGAGTTCA ACTACCGTAC CATCGAGGAA TCGCCGGCCA ACAATATCGT 
GTGGCTGCTC TCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

???-ENaC is inhibited by CFTR but stimulated by cAMP in
American journal of physiology. Lung cellular and molecular physiology312(2)L277-L287(2017 Feb)
Rauh R,Hoerner C,Korbmacher C

Altered ENaC is Associated With Aortic Baroreceptor Dysfunction in Chronic Heart Failure.
American journal of hypertension29(5)582-9(2016 May)
Li YL,Zhang D,Tu H,Muelleman RL

[Expression of Catechol-O-Methyltransferase (Comt), Mineralocorticoid Receptor (Mlr), and Epithelial Sodium Channel (ENaC) Genes in Kidneys of Hypertensive ISIAH Rats at Rest and during Response to Stress].
Genetika52(2)206-14(2016 Feb)
Abramova TO,Smolenskaya SE,Antonov EV,Redina OE,Markel AL

Heme oxygenase-1 promotes migration and ?-epithelial Na+ channel expression in cytotrophoblasts and ischemic placentas.
American journal of physiology. Regulatory, integrative and comparative physiology306(9)R641-6(2014 May)
Warrington JP,Coleman K,Skaggs C,Hosick PA,George EM,Stec DE,Ryan MJ,Granger JP,Drummond HA

Identification of the SPLUNC1 ENaC-inhibitory domain yields novel strategies to treat sodium hyperabsorption in cystic fibrosis airway epithelial cultures.
American journal of physiology. Lung cellular and molecular physiology305(12)L990-L1001(2013 Dec)
Hobbs CA,Blanchard MG,Alijevic O,Tan CD,Kellenberger S,Bencharit S,Cao R,Kesimer M,Walton WG,Henderson AG,Redinbo MR,Stutts MJ,Tarran R

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Scnn1b cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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