SCNN1B cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SCNN1B
Entrez Gene ID	6338
Full Name	sodium channel epithelial 1 beta subunit
Synonyms	BESC1,ENaCb,ENaCbeta,SCNEB
General protein information	Preferred Names sodium channel epithelial 1 beta subunit Names amiloride-sensitive sodium channel subunit beta amiloride-sensitive sodium channel subunit beta 1 beta-ENaC beta-NaCH epithelial Na(+) channel subunit beta epithelial sodium channel beta-2 subunit epithelial sodium channel beta-3 subunit nasal epithelial sodium channel beta subunit nonvoltage-gated sodium channel 1 subunit beta sodium channel, non-voltage-gated 1, beta subunit sodium channel, nonvoltage-gated 1, beta
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 16 Map Location: 16p12.2
Summary	Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the beta subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), and Liddle syndrome. [provided by RefSeq, Apr 2009].
Disorder MIM:	600760
Disorder Html:	Liddle syndrome, 177200 (3); Pseudohypoaldosteronism, type I, 264350 (3); Bronchiectasis with or without elevated sweat chloride 1, 211400 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_000336.2	NP_000327.2	amiloride-sensitive sodium channel subunit beta
XM_011545913.2	XP_011544215.1	amiloride-sensitive sodium channel subunit beta isoform X2
XM_011545914.1	XP_011544216.1	amiloride-sensitive sodium channel subunit beta isoform X3
XM_017023526.1	XP_016879015.1	amiloride-sensitive sodium channel subunit beta isoform X4
NM_000336.3	NP_000327.2	amiloride-sensitive sodium channel subunit beta
XM_017023525.1	XP_016879014.1	amiloride-sensitive sodium channel subunit beta isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	SCNN1B	NP_000327.2
Rattus norvegicus (Norway rat)	Scnn1b	NP_036780.1
Gallus gallus (chicken)	SCNN1B	XP_425247.3
Xenopus tropicalis (tropical clawed frog)	scnn1b	NP_001072437.1
	SCNN1B	XP_001093933.1
Canis lupus familiaris (dog)	SCNN1B	XP_005621478.1
Mus musculus (house mouse)	Scnn1b	NP_035455.1
Bos taurus (cattle)	SCNN1B	NP_001091544.1
Pan troglodytes (chimpanzee)	SCNN1B	XP_001161438.2

Gene Ontology
Bibliography

Related articles in PubMed

Mapping allosteric linkage to channel gating of extracellular domains in the human epithelial sodium channel.
Shobair M, Popov KI, Dang YL, He H, Stutts MJ, Dokholyan NV
The Journal of biological chemistry(2018 Jan)

The Epithelial Sodium Channel Is a Modifier of the Long-Term Nonprogressive Phenotype Associated with F508del CFTR Mutations.
Agrawal PB, Wang R, Li HL, Schmitz-Abe K, Simone-Roach C, Chen J, Shi J, Louie T, Sheng S, Towne MC, Brainson CF, Matthay MA, Kim CF, Bamshad M, Emond MJ, Gerard NP, Kleyman TR, Gerard C
American journal of respiratory cell and molecular biology57(6)711-720(2017 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The Epithelial Sodium Channel Is a Modifier of the Long-Term Nonprogressive Phenotype Associated with F508del CFTR Mutations
Title: The Epithelial Sodium Channel Is a Modifier of the Long-Term Nonprogressive Phenotype Associated with F508del CFTR Mutations.

Results identify SCNN1B as a tumor-suppressive function that triggers UPR in gastric cancer cells, with implications for its potential clinical applications as a survival biomarker in gastric cancer patients.
Title: Sodium Channel Subunit SCNN1B Suppresses Gastric Cancer Growth and Metastasis via GRP78 Degradation.

The derlin-1 pathway therefore may represent a significant early checkpoint in the recognition and degradation of ENaC in mammalian cells.
Title: Derlin-1 promotes ubiquitylation and degradation of the epithelial Na

deltabetagamma-ENaC is inhibited by CFTR but activated by cyclic AMP.
Title: ???-ENaC is inhibited by CFTR but stimulated by cAMP in

These results indicated a significant association between EH and SCNN1B methylation, which was affected by age, gender and antihypertensive therapy.
Title: Association of SCNN1B promoter methylation with essential hypertension.

The following SCNN1B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SCNN1B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu18452	NM_000336.3 Latest version!	Homo sapiens sodium channel epithelial 1 subunit beta (SCNN1B), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
OHu60387	XM_011545913.2 Latest version!	Homo sapiens sodium channel epithelial 1 subunit beta (SCNN1B), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu60388	XM_011545914.1 Latest version!	Homo sapiens sodium channel epithelial 1 subunit beta (SCNN1B), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu86191	XM_017023525.1 Latest version!	Homo sapiens sodium channel epithelial 1 subunit beta (SCNN1B), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
OHu86192	XM_017023526.1 Latest version!	Homo sapiens sodium channel epithelial 1 subunit beta (SCNN1B), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
View Old Accession Versions >>
OHu18452	NM_000336.2	Homo sapiens sodium channel epithelial 1 beta subunit (SCNN1B), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SCNN1B ( NM_000336.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_000327.2 Homo sapiens sodium channel epithelial 1 beta subunit (SCNN1B), mRNA.

Price & Availability↑

CloneID	OHu18452
Clone ID Related Accession (Same CDS sequence)	NM_000336.2 , NM_000336.3
Accession Version	NM_000336.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1923bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-10
Organism	Homo sapiens(human)
Product	amiloride-sensitive sodium channel subunit beta
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AU105979.1, BC036352.1 and L36593.1. This sequence is a reference standard in the RefSeqGene project. On Jan 31, 2007 this sequence version replaced NM_000336.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC036352.1, X87159.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCACGTGA AGAAGTACCT GCTGAAGGGC CTGCATCGGC TGCAGAAGGG CCCCGGCTAC 
ACGTACAAGG AGCTGCTGGT GTGGTACTGC GACAACACCA ACACCCACGG CCCCAAGCGC 
ATCATCTGTG AGGGGCCCAA GAAGAAAGCC ATGTGGTTCC TGCTCACCCT GCTCTTCGCC 
GCCCTCGTCT GCTGGCAGTG GGGCATCTTC ATCAGGACCT ACTTGAGCTG GGAGGTCAGC 
GTCTCCCTCT CCGTAGGCTT CAAGACCATG GACTTCCCTG CCGTCACCAT CTGCAATGCT 
AGCCCCTTCA AGTATTCCAA AATCAAGCAT TTGCTGAAGG ACCTGGATGA GCTGATGGAA 
GCTGTCCTGG AGAGAATCCT GGCTCCTGAG CTAAGCCATG CCAATGCCAC CAGGAACCTG 
AACTTCTCCA TCTGGAACCA CACACCCCTG GTCCTTATTG ATGAACGGAA CCCCCACCAC 
CCCATGGTCC TTGATCTCTT TGGAGACAAC CACAATGGCT TAACAAGCAG CTCAGCATCA 
GAAAAGATCT GTAATGCCCA CGGGTGCAAA ATGGCCATGA GACTATGTAG CCTCAACAGG 
ACCCAGTGTA CCTTCCGGAA CTTCACCAGT GCTACCCAGG CATTGACAGA GTGGTACATC 
CTGCAGGCCA CCAACATCTT TGCACAGGTG CCACAGCAGG AGCTAGTAGA GATGAGCTAC 
CCCGGCGAGC AGATGATCCT GGCCTGCCTA TTCGGAGCTG AGCCCTGCAA CTACCGGAAC 
TTCACGTCCA TCTTCTACCC TCACTATGGC AACTGTTACA TCTTCAACTG GGGCATGACA 
GAGAAGGCAC TTCCTTCGGC CAACCCTGGA ACTGAATTCG GCCTGAAGTT GATCCTGGAC 
ATAGGCCAGG AAGACTACGT CCCCTTCCTT GCGTCCACGG CCGGGGTCAG GCTGATGCTT 
CACGAGCAGA GGTCATACCC CTTCATCAGA GATGAGGGCA TCTACGCCAT GTCGGGGACA 
GAGACGTCCA TCGGGGTACT CGTGGACAAG CTTCAGCGCA TGGGGGAGCC CTACAGCCCG 
TGCACCGTGA ATGGTTCTGA GGTCCCCGTC CAAAACTTCT ACAGTGACTA CAACACGACC 
TACTCCATCC AGGCCTGTCT TCGCTCCTGC TTCCAAGACC ACATGATCCG TAACTGCAAC 
TGTGGCCACT ACCTGTACCC ACTGCCCCGT GGGGAGAAAT ACTGCAACAA CCGGGACTTC 
CCAGACTGGG CCCATTGCTA CTCAGATCTA CAGATGAGCG TGGCGCAGAG AGAGACCTGC 
ATTGGCATGT GCAAGGAGTC CTGCAATGAC ACCCAGTACA AGATGACCAT CTCCATGGCT 
GACTGGCCTT CTGAGGCCTC CGAGGACTGG ATTTTCCACG TCTTGTCTCA GGAGCGGGAC 
CAAAGCACCA ATATCACCCT GAGCAGGAAG GGAATTGTCA AGCTCAACAT CTACTTCCAA 
GAATTTAACT ATCGCACCAT TGAAGAATCA GCAGCCAATA ACATCGTCTG GCTGCTCTCG 
AATCTGGGTG GCCAGTTTGG CTTCTGGATG GGGGGCTCTG TGCTGTGCCT CATCGAGTTT 
GGGGAGATCA TCATCGACTT TGTGTGGATC ACCATCATCA AGCTGGTGGC CTTGGCCAAG 
AGCCTACGGC AGCGGCGAGC CCAAGCCAGC TACGCTGGCC CACCGCCCAC CGTGGCCGAG 
CTGGTGGAGG CCCACACCAA CTTTGGCTTC CAGCCTGACA CGGCCCCCCG CAGCCCCAAC 
ACTGGGCCCT ACCCCAGTGA GCAGGCCCTG CCCATCCCAG GCACCCCGCC CCCCAACTAT 
GACTCCCTGC GTCTGCAGCC GCTGGACGTC ATCGAGTCTG ACAGTGAGGG TGATGCCATC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000327.2
CDS	177..2099
Translation	MHVKKYLLKGLHRLQKGPGYTYKELLVWYCDNTNTHGPKRIICEGPKKKAMWFLLTLLFAALVCWQWGIFIRTYLSWEVSVSLSVGFKTMDFPAVTICNASPFKYSKIKHLLKDLDELMEAVLERILAPELSHANATRNLNFSIWNHTPLVLIDERNPHHPMVLDLFGDNHNGLTSSSASEKICNAHGCKMAMRLCSLNRTQCTFRNFTSATQALTEWYILQATNIFAQVPQQELVEMSYPGEQMILACLFGAEPCNYRNFTSIFYPHYGNCYIFNWGMTEKALPSANPGTEFGLKLILDIGQEDYVPFLASTAGVRLMLHEQRSYPFIRDEGIYAMSGTETSIGVLVDKLQRMGEPYSPCTVNGSEVPVQNFYSDYNTTYSIQACLRSCFQDHMIRNCNCGHYLYPLPRGEKYCNNRDFPDWAHCYSDLQMSVAQRETCIGMCKESCNDTQYKMTISMADWPSEASEDWIFHVLSQERDQSTNITLSRKGIVKLNIYFQEFNYRTIEESAANNIVWLLSNLGGQFGFWMGGSVLCLIEFGEIIIDFVWITIIKLVALAKSLRQRRAQASYAGPPPTVAELVEAHTNFGFQPDTAPRSPNTGPYPSEQALPIPGTPPPNYDSLRLQPLDVIESDSEGDAI

Target ORF information:

RefSeq Version	NM_000336.2
Organism	Homo sapiens(human)
Definition	Homo sapiens sodium channel epithelial 1 beta subunit (SCNN1B), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000336.2

ORF Insert Sequence:

ATGCACGTGA AGAAGTACCT GCTGAAGGGC CTGCATCGGC TGCAGAAGGG CCCCGGCTAC 
ACGTACAAGG AGCTGCTGGT GTGGTACTGC GACAACACCA ACACCCACGG CCCCAAGCGC 
ATCATCTGTG AGGGGCCCAA GAAGAAAGCC ATGTGGTTCC TGCTCACCCT GCTCTTCGCC 
GCCCTCGTCT GCTGGCAGTG GGGCATCTTC ATCAGGACCT ACTTGAGCTG GGAGGTCAGC 
GTCTCCCTCT CCGTAGGCTT CAAGACCATG GACTTCCCTG CCGTCACCAT CTGCAATGCT 
AGCCCCTTCA AGTATTCCAA AATCAAGCAT TTGCTGAAGG ACCTGGATGA GCTGATGGAA 
GCTGTCCTGG AGAGAATCCT GGCTCCTGAG CTAAGCCATG CCAATGCCAC CAGGAACCTG 
AACTTCTCCA TCTGGAACCA CACACCCCTG GTCCTTATTG ATGAACGGAA CCCCCACCAC 
CCCATGGTCC TTGATCTCTT TGGAGACAAC CACAATGGCT TAACAAGCAG CTCAGCATCA 
GAAAAGATCT GTAATGCCCA CGGGTGCAAA ATGGCCATGA GACTATGTAG CCTCAACAGG 
ACCCAGTGTA CCTTCCGGAA CTTCACCAGT GCTACCCAGG CATTGACAGA GTGGTACATC 
CTGCAGGCCA CCAACATCTT TGCACAGGTG CCACAGCAGG AGCTAGTAGA GATGAGCTAC 
CCCGGCGAGC AGATGATCCT GGCCTGCCTA TTCGGAGCTG AGCCCTGCAA CTACCGGAAC 
TTCACGTCCA TCTTCTACCC TCACTATGGC AACTGTTACA TCTTCAACTG GGGCATGACA 
GAGAAGGCAC TTCCTTCGGC CAACCCTGGA ACTGAATTCG GCCTGAAGTT GATCCTGGAC 
ATAGGCCAGG AAGACTACGT CCCCTTCCTT GCGTCCACGG CCGGGGTCAG GCTGATGCTT 
CACGAGCAGA GGTCATACCC CTTCATCAGA GATGAGGGCA TCTACGCCAT GTCGGGGACA 
GAGACGTCCA TCGGGGTACT CGTGGACAAG CTTCAGCGCA TGGGGGAGCC CTACAGCCCG 
TGCACCGTGA ATGGTTCTGA GGTCCCCGTC CAAAACTTCT ACAGTGACTA CAACACGACC 
TACTCCATCC AGGCCTGTCT TCGCTCCTGC TTCCAAGACC ACATGATCCG TAACTGCAAC 
TGTGGCCACT ACCTGTACCC ACTGCCCCGT GGGGAGAAAT ACTGCAACAA CCGGGACTTC 
CCAGACTGGG CCCATTGCTA CTCAGATCTA CAGATGAGCG TGGCGCAGAG AGAGACCTGC 
ATTGGCATGT GCAAGGAGTC CTGCAATGAC ACCCAGTACA AGATGACCAT CTCCATGGCT 
GACTGGCCTT CTGAGGCCTC CGAGGACTGG ATTTTCCACG TCTTGTCTCA GGAGCGGGAC 
CAAAGCACCA ATATCACCCT GAGCAGGAAG GGAATTGTCA AGCTCAACAT CTACTTCCAA 
GAATTTAACT ATCGCACCAT TGAAGAATCA GCAGCCAATA ACATCGTCTG GCTGCTCTCG 
AATCTGGGTG GCCAGTTTGG CTTCTGGATG GGGGGCTCTG TGCTGTGCCT CATCGAGTTT 
GGGGAGATCA TCATCGACTT TGTGTGGATC ACCATCATCA AGCTGGTGGC CTTGGCCAAG 
AGCCTACGGC AGCGGCGAGC CCAAGCCAGC TACGCTGGCC CACCGCCCAC CGTGGCCGAG 
CTGGTGGAGG CCCACACCAA CTTTGGCTTC CAGCCTGACA CGGCCCCCCG CAGCCCCAAC 
ACTGGGCCCT ACCCCAGTGA GCAGGCCCTG CCCATCCCAG GCACCCCGCC CCCCAACTAT 
GACTCCCTGC GTCTGCAGCC GCTGGACGTC ATCGAGTCTG ACAGTGAGGG TGATGCCATC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SCNN1B ( NM_000336.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_000327.2 Homo sapiens sodium channel epithelial 1 subunit beta (SCNN1B), mRNA.

Price & Availability↑

CloneID	OHu18452
Clone ID Related Accession (Same CDS sequence)	NM_000336.2 , NM_000336.3
Accession Version	NM_000336.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1923bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	amiloride-sensitive sodium channel subunit beta
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AU105979.1, BC036352.1 and L36593.1. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_000336.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: MH503766.1, BC036352.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000343070.7/ ENSP00000345751.2 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCACGTGA AGAAGTACCT GCTGAAGGGC CTGCATCGGC TGCAGAAGGG CCCCGGCTAC 
ACGTACAAGG AGCTGCTGGT GTGGTACTGC GACAACACCA ACACCCACGG CCCCAAGCGC 
ATCATCTGTG AGGGGCCCAA GAAGAAAGCC ATGTGGTTCC TGCTCACCCT GCTCTTCGCC 
GCCCTCGTCT GCTGGCAGTG GGGCATCTTC ATCAGGACCT ACTTGAGCTG GGAGGTCAGC 
GTCTCCCTCT CCGTAGGCTT CAAGACCATG GACTTCCCTG CCGTCACCAT CTGCAATGCT 
AGCCCCTTCA AGTATTCCAA AATCAAGCAT TTGCTGAAGG ACCTGGATGA GCTGATGGAA 
GCTGTCCTGG AGAGAATCCT GGCTCCTGAG CTAAGCCATG CCAATGCCAC CAGGAACCTG 
AACTTCTCCA TCTGGAACCA CACACCCCTG GTCCTTATTG ATGAACGGAA CCCCCACCAC 
CCCATGGTCC TTGATCTCTT TGGAGACAAC CACAATGGCT TAACAAGCAG CTCAGCATCA 
GAAAAGATCT GTAATGCCCA CGGGTGCAAA ATGGCCATGA GACTATGTAG CCTCAACAGG 
ACCCAGTGTA CCTTCCGGAA CTTCACCAGT GCTACCCAGG CATTGACAGA GTGGTACATC 
CTGCAGGCCA CCAACATCTT TGCACAGGTG CCACAGCAGG AGCTAGTAGA GATGAGCTAC 
CCCGGCGAGC AGATGATCCT GGCCTGCCTA TTCGGAGCTG AGCCCTGCAA CTACCGGAAC 
TTCACGTCCA TCTTCTACCC TCACTATGGC AACTGTTACA TCTTCAACTG GGGCATGACA 
GAGAAGGCAC TTCCTTCGGC CAACCCTGGA ACTGAATTCG GCCTGAAGTT GATCCTGGAC 
ATAGGCCAGG AAGACTACGT CCCCTTCCTT GCGTCCACGG CCGGGGTCAG GCTGATGCTT 
CACGAGCAGA GGTCATACCC CTTCATCAGA GATGAGGGCA TCTACGCCAT GTCGGGGACA 
GAGACGTCCA TCGGGGTACT CGTGGACAAG CTTCAGCGCA TGGGGGAGCC CTACAGCCCG 
TGCACCGTGA ATGGTTCTGA GGTCCCCGTC CAAAACTTCT ACAGTGACTA CAACACGACC 
TACTCCATCC AGGCCTGTCT TCGCTCCTGC TTCCAAGACC ACATGATCCG TAACTGCAAC 
TGTGGCCACT ACCTGTACCC ACTGCCCCGT GGGGAGAAAT ACTGCAACAA CCGGGACTTC 
CCAGACTGGG CCCATTGCTA CTCAGATCTA CAGATGAGCG TGGCGCAGAG AGAGACCTGC 
ATTGGCATGT GCAAGGAGTC CTGCAATGAC ACCCAGTACA AGATGACCAT CTCCATGGCT 
GACTGGCCTT CTGAGGCCTC CGAGGACTGG ATTTTCCACG TCTTGTCTCA GGAGCGGGAC 
CAAAGCACCA ATATCACCCT GAGCAGGAAG GGAATTGTCA AGCTCAACAT CTACTTCCAA 
GAATTTAACT ATCGCACCAT TGAAGAATCA GCAGCCAATA ACATCGTCTG GCTGCTCTCG 
AATCTGGGTG GCCAGTTTGG CTTCTGGATG GGGGGCTCTG TGCTGTGCCT CATCGAGTTT 
GGGGAGATCA TCATCGACTT TGTGTGGATC ACCATCATCA AGCTGGTGGC CTTGGCCAAG 
AGCCTACGGC AGCGGCGAGC CCAAGCCAGC TACGCTGGCC CACCGCCCAC CGTGGCCGAG 
CTGGTGGAGG CCCACACCAA CTTTGGCTTC CAGCCTGACA CGGCCCCCCG CAGCCCCAAC 
ACTGGGCCCT ACCCCAGTGA GCAGGCCCTG CCCATCCCAG GCACCCCGCC CCCCAACTAT 
GACTCCCTGC GTCTGCAGCC GCTGGACGTC ATCGAGTCTG ACAGTGAGGG TGATGCCATC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000327.2
CDS	145..2067
Translation	MHVKKYLLKGLHRLQKGPGYTYKELLVWYCDNTNTHGPKRIICEGPKKKAMWFLLTLLFAALVCWQWGIFIRTYLSWEVSVSLSVGFKTMDFPAVTICNASPFKYSKIKHLLKDLDELMEAVLERILAPELSHANATRNLNFSIWNHTPLVLIDERNPHHPMVLDLFGDNHNGLTSSSASEKICNAHGCKMAMRLCSLNRTQCTFRNFTSATQALTEWYILQATNIFAQVPQQELVEMSYPGEQMILACLFGAEPCNYRNFTSIFYPHYGNCYIFNWGMTEKALPSANPGTEFGLKLILDIGQEDYVPFLASTAGVRLMLHEQRSYPFIRDEGIYAMSGTETSIGVLVDKLQRMGEPYSPCTVNGSEVPVQNFYSDYNTTYSIQACLRSCFQDHMIRNCNCGHYLYPLPRGEKYCNNRDFPDWAHCYSDLQMSVAQRETCIGMCKESCNDTQYKMTISMADWPSEASEDWIFHVLSQERDQSTNITLSRKGIVKLNIYFQEFNYRTIEESAANNIVWLLSNLGGQFGFWMGGSVLCLIEFGEIIIDFVWITIIKLVALAKSLRQRRAQASYAGPPPTVAELVEAHTNFGFQPDTAPRSPNTGPYPSEQALPIPGTPPPNYDSLRLQPLDVIESDSEGDAI

Target ORF information:

RefSeq Version	NM_000336.3
Organism	Homo sapiens(human)
Definition	Homo sapiens sodium channel epithelial 1 subunit beta (SCNN1B), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000336.3

ORF Insert Sequence:

ATGCACGTGA AGAAGTACCT GCTGAAGGGC CTGCATCGGC TGCAGAAGGG CCCCGGCTAC 
ACGTACAAGG AGCTGCTGGT GTGGTACTGC GACAACACCA ACACCCACGG CCCCAAGCGC 
ATCATCTGTG AGGGGCCCAA GAAGAAAGCC ATGTGGTTCC TGCTCACCCT GCTCTTCGCC 
GCCCTCGTCT GCTGGCAGTG GGGCATCTTC ATCAGGACCT ACTTGAGCTG GGAGGTCAGC 
GTCTCCCTCT CCGTAGGCTT CAAGACCATG GACTTCCCTG CCGTCACCAT CTGCAATGCT 
AGCCCCTTCA AGTATTCCAA AATCAAGCAT TTGCTGAAGG ACCTGGATGA GCTGATGGAA 
GCTGTCCTGG AGAGAATCCT GGCTCCTGAG CTAAGCCATG CCAATGCCAC CAGGAACCTG 
AACTTCTCCA TCTGGAACCA CACACCCCTG GTCCTTATTG ATGAACGGAA CCCCCACCAC 
CCCATGGTCC TTGATCTCTT TGGAGACAAC CACAATGGCT TAACAAGCAG CTCAGCATCA 
GAAAAGATCT GTAATGCCCA CGGGTGCAAA ATGGCCATGA GACTATGTAG CCTCAACAGG 
ACCCAGTGTA CCTTCCGGAA CTTCACCAGT GCTACCCAGG CATTGACAGA GTGGTACATC 
CTGCAGGCCA CCAACATCTT TGCACAGGTG CCACAGCAGG AGCTAGTAGA GATGAGCTAC 
CCCGGCGAGC AGATGATCCT GGCCTGCCTA TTCGGAGCTG AGCCCTGCAA CTACCGGAAC 
TTCACGTCCA TCTTCTACCC TCACTATGGC AACTGTTACA TCTTCAACTG GGGCATGACA 
GAGAAGGCAC TTCCTTCGGC CAACCCTGGA ACTGAATTCG GCCTGAAGTT GATCCTGGAC 
ATAGGCCAGG AAGACTACGT CCCCTTCCTT GCGTCCACGG CCGGGGTCAG GCTGATGCTT 
CACGAGCAGA GGTCATACCC CTTCATCAGA GATGAGGGCA TCTACGCCAT GTCGGGGACA 
GAGACGTCCA TCGGGGTACT CGTGGACAAG CTTCAGCGCA TGGGGGAGCC CTACAGCCCG 
TGCACCGTGA ATGGTTCTGA GGTCCCCGTC CAAAACTTCT ACAGTGACTA CAACACGACC 
TACTCCATCC AGGCCTGTCT TCGCTCCTGC TTCCAAGACC ACATGATCCG TAACTGCAAC 
TGTGGCCACT ACCTGTACCC ACTGCCCCGT GGGGAGAAAT ACTGCAACAA CCGGGACTTC 
CCAGACTGGG CCCATTGCTA CTCAGATCTA CAGATGAGCG TGGCGCAGAG AGAGACCTGC 
ATTGGCATGT GCAAGGAGTC CTGCAATGAC ACCCAGTACA AGATGACCAT CTCCATGGCT 
GACTGGCCTT CTGAGGCCTC CGAGGACTGG ATTTTCCACG TCTTGTCTCA GGAGCGGGAC 
CAAAGCACCA ATATCACCCT GAGCAGGAAG GGAATTGTCA AGCTCAACAT CTACTTCCAA 
GAATTTAACT ATCGCACCAT TGAAGAATCA GCAGCCAATA ACATCGTCTG GCTGCTCTCG 
AATCTGGGTG GCCAGTTTGG CTTCTGGATG GGGGGCTCTG TGCTGTGCCT CATCGAGTTT 
GGGGAGATCA TCATCGACTT TGTGTGGATC ACCATCATCA AGCTGGTGGC CTTGGCCAAG 
AGCCTACGGC AGCGGCGAGC CCAAGCCAGC TACGCTGGCC CACCGCCCAC CGTGGCCGAG 
CTGGTGGAGG CCCACACCAA CTTTGGCTTC CAGCCTGACA CGGCCCCCCG CAGCCCCAAC 
ACTGGGCCCT ACCCCAGTGA GCAGGCCCTG CCCATCCCAG GCACCCCGCC CCCCAACTAT 
GACTCCCTGC GTCTGCAGCC GCTGGACGTC ATCGAGTCTG ACAGTGAGGG TGATGCCATC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SCNN1B ( XM_011545913.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011544215.1 Homo sapiens sodium channel epithelial 1 subunit beta (SCNN1B), transcript variant X2, mRNA.

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CloneID	OHu60387
Clone ID Related Accession (Same CDS sequence)	XM_011545913.2
Accession Version	XM_011545913.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1956bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	amiloride-sensitive sodium channel subunit beta isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000016.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011545913.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGAAAC CAGGGCACAG AGAGGGTGCC ACTATGCACG TGAAGAAGTA CCTGCTGAAG 
GGCCTGCATC GGCTGCAGAA GGGCCCCGGC TACACGTACA AGGAGCTGCT GGTGTGGTAC 
TGCGACAACA CCAACACCCA CGGCCCCAAG CGCATCATCT GTGAGGGGCC CAAGAAGAAA 
GCCATGTGGT TCCTGCTCAC CCTGCTCTTC GCCGCCCTCG TCTGCTGGCA GTGGGGCATC 
TTCATCAGGA CCTACTTGAG CTGGGAGGTC AGCGTCTCCC TCTCCGTAGG CTTCAAGACC 
ATGGACTTCC CTGCCGTCAC CATCTGCAAT GCTAGCCCCT TCAAGTATTC CAAAATCAAG 
CATTTGCTGA AGGACCTGGA TGAGCTGATG GAAGCTGTCC TGGAGAGAAT CCTGGCTCCT 
GAGCTAAGCC ATGCCAATGC CACCAGGAAC CTGAACTTCT CCATCTGGAA CCACACACCC 
CTGGTCCTTA TTGATGAACG GAACCCCCAC CACCCCATGG TCCTTGATCT CTTTGGAGAC 
AACCACAATG GCTTAACAAG CAGCTCAGCA TCAGAAAAGA TCTGTAATGC CCACGGGTGC 
AAAATGGCCA TGAGACTATG TAGCCTCAAC AGGACCCAGT GTACCTTCCG GAACTTCACC 
AGTGCTACCC AGGCATTGAC AGAGTGGTAC ATCCTGCAGG CCACCAACAT CTTTGCACAG 
GTGCCACAGC AGGAGCTAGT AGAGATGAGC TACCCCGGCG AGCAGATGAT CCTGGCCTGC 
CTATTCGGAG CTGAGCCCTG CAACTACCGG AACTTCACGT CCATCTTCTA CCCTCACTAT 
GGCAACTGTT ACATCTTCAA CTGGGGCATG ACAGAGAAGG CACTTCCTTC GGCCAACCCT 
GGAACTGAAT TCGGCCTGAA GTTGATCCTG GACATAGGCC AGGAAGACTA CGTCCCCTTC 
CTTGCGTCCA CGGCCGGGGT CAGGCTGATG CTTCACGAGC AGAGGTCATA CCCCTTCATC 
AGAGATGAGG GCATCTACGC CATGTCGGGG ACAGAGACGT CCATCGGGGT ACTCGTGGAC 
AAGCTTCAGC GCATGGGGGA GCCCTACAGC CCGTGCACCG TGAATGGTTC TGAGGTCCCC 
GTCCAAAACT TCTACAGTGA CTACAACACG ACCTACTCCA TCCAGGCCTG TCTTCGCTCC 
TGCTTCCAAG ACCACATGAT CCGTAACTGC AACTGTGGCC ACTACCTGTA CCCACTGCCC 
CGTGGGGAGA AATACTGCAA CAACCGGGAC TTCCCAGACT GGGCCCATTG CTACTCAGAT 
CTACAGATGA GCGTGGCGCA GAGAGAGACC TGCATTGGCA TGTGCAAGGA GTCCTGCAAT 
GACACCCAGT ACAAGATGAC CATCTCCATG GCTGACTGGC CTTCTGAGGC CTCCGAGGAC 
TGGATTTTCC ACGTCTTGTC TCAGGAGCGG GACCAAAGCA CCAATATCAC CCTGAGCAGG 
AAGGGAATTG TCAAGCTCAA CATCTACTTC CAAGAATTTA ACTATCGCAC CATTGAAGAA 
TCAGCAGCCA ATAACATCGT CTGGCTGCTC TCGAATCTGG GTGGCCAGTT TGGCTTCTGG 
ATGGGGGGCT CTGTGCTGTG CCTCATCGAG TTTGGGGAGA TCATCATCGA CTTTGTGTGG 
ATCACCATCA TCAAGCTGGT GGCCTTGGCC AAGAGCCTAC GGCAGCGGCG AGCCCAAGCC 
AGCTACGCTG GCCCACCGCC CACCGTGGCC GAGCTGGTGG AGGCCCACAC CAACTTTGGC 
TTCCAGCCTG ACACGGCCCC CCGCAGCCCC AACACTGGGC CCTACCCCAG TGAGCAGGCC 
CTGCCCATCC CAGGCACCCC GCCCCCCAAC TATGACTCCC TGCGTCTGCA GCCGCTGGAC 
GTCATCGAGT CTGACAGTGA GGGTGATGCC ATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011544215.1
CDS	136..2091
Translation	MGKPGHREGATMHVKKYLLKGLHRLQKGPGYTYKELLVWYCDNTNTHGPKRIICEGPKKKAMWFLLTLLFAALVCWQWGIFIRTYLSWEVSVSLSVGFKTMDFPAVTICNASPFKYSKIKHLLKDLDELMEAVLERILAPELSHANATRNLNFSIWNHTPLVLIDERNPHHPMVLDLFGDNHNGLTSSSASEKICNAHGCKMAMRLCSLNRTQCTFRNFTSATQALTEWYILQATNIFAQVPQQELVEMSYPGEQMILACLFGAEPCNYRNFTSIFYPHYGNCYIFNWGMTEKALPSANPGTEFGLKLILDIGQEDYVPFLASTAGVRLMLHEQRSYPFIRDEGIYAMSGTETSIGVLVDKLQRMGEPYSPCTVNGSEVPVQNFYSDYNTTYSIQACLRSCFQDHMIRNCNCGHYLYPLPRGEKYCNNRDFPDWAHCYSDLQMSVAQRETCIGMCKESCNDTQYKMTISMADWPSEASEDWIFHVLSQERDQSTNITLSRKGIVKLNIYFQEFNYRTIEESAANNIVWLLSNLGGQFGFWMGGSVLCLIEFGEIIIDFVWITIIKLVALAKSLRQRRAQASYAGPPPTVAELVEAHTNFGFQPDTAPRSPNTGPYPSEQALPIPGTPPPNYDSLRLQPLDVIESDSEGDAI

Target ORF information:

RefSeq Version	XM_011545913.2
Organism	Homo sapiens(human)
Definition	Homo sapiens sodium channel epithelial 1 subunit beta (SCNN1B), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011545913.2

ORF Insert Sequence:

ATGGGGAAAC CAGGGCACAG AGAGGGTGCC ACTATGCACG TGAAGAAGTA CCTGCTGAAG 
GGCCTGCATC GGCTGCAGAA GGGCCCCGGC TACACGTACA AGGAGCTGCT GGTGTGGTAC 
TGCGACAACA CCAACACCCA CGGCCCCAAG CGCATCATCT GTGAGGGGCC CAAGAAGAAA 
GCCATGTGGT TCCTGCTCAC CCTGCTCTTC GCCGCCCTCG TCTGCTGGCA GTGGGGCATC 
TTCATCAGGA CCTACTTGAG CTGGGAGGTC AGCGTCTCCC TCTCCGTAGG CTTCAAGACC 
ATGGACTTCC CTGCCGTCAC CATCTGCAAT GCTAGCCCCT TCAAGTATTC CAAAATCAAG 
CATTTGCTGA AGGACCTGGA TGAGCTGATG GAAGCTGTCC TGGAGAGAAT CCTGGCTCCT 
GAGCTAAGCC ATGCCAATGC CACCAGGAAC CTGAACTTCT CCATCTGGAA CCACACACCC 
CTGGTCCTTA TTGATGAACG GAACCCCCAC CACCCCATGG TCCTTGATCT CTTTGGAGAC 
AACCACAATG GCTTAACAAG CAGCTCAGCA TCAGAAAAGA TCTGTAATGC CCACGGGTGC 
AAAATGGCCA TGAGACTATG TAGCCTCAAC AGGACCCAGT GTACCTTCCG GAACTTCACC 
AGTGCTACCC AGGCATTGAC AGAGTGGTAC ATCCTGCAGG CCACCAACAT CTTTGCACAG 
GTGCCACAGC AGGAGCTAGT AGAGATGAGC TACCCCGGCG AGCAGATGAT CCTGGCCTGC 
CTATTCGGAG CTGAGCCCTG CAACTACCGG AACTTCACGT CCATCTTCTA CCCTCACTAT 
GGCAACTGTT ACATCTTCAA CTGGGGCATG ACAGAGAAGG CACTTCCTTC GGCCAACCCT 
GGAACTGAAT TCGGCCTGAA GTTGATCCTG GACATAGGCC AGGAAGACTA CGTCCCCTTC 
CTTGCGTCCA CGGCCGGGGT CAGGCTGATG CTTCACGAGC AGAGGTCATA CCCCTTCATC 
AGAGATGAGG GCATCTACGC CATGTCGGGG ACAGAGACGT CCATCGGGGT ACTCGTGGAC 
AAGCTTCAGC GCATGGGGGA GCCCTACAGC CCGTGCACCG TGAATGGTTC TGAGGTCCCC 
GTCCAAAACT TCTACAGTGA CTACAACACG ACCTACTCCA TCCAGGCCTG TCTTCGCTCC 
TGCTTCCAAG ACCACATGAT CCGTAACTGC AACTGTGGCC ACTACCTGTA CCCACTGCCC 
CGTGGGGAGA AATACTGCAA CAACCGGGAC TTCCCAGACT GGGCCCATTG CTACTCAGAT 
CTACAGATGA GCGTGGCGCA GAGAGAGACC TGCATTGGCA TGTGCAAGGA GTCCTGCAAT 
GACACCCAGT ACAAGATGAC CATCTCCATG GCTGACTGGC CTTCTGAGGC CTCCGAGGAC 
TGGATTTTCC ACGTCTTGTC TCAGGAGCGG GACCAAAGCA CCAATATCAC CCTGAGCAGG 
AAGGGAATTG TCAAGCTCAA CATCTACTTC CAAGAATTTA ACTATCGCAC CATTGAAGAA 
TCAGCAGCCA ATAACATCGT CTGGCTGCTC TCGAATCTGG GTGGCCAGTT TGGCTTCTGG 
ATGGGGGGCT CTGTGCTGTG CCTCATCGAG TTTGGGGAGA TCATCATCGA CTTTGTGTGG 
ATCACCATCA TCAAGCTGGT GGCCTTGGCC AAGAGCCTAC GGCAGCGGCG AGCCCAAGCC 
AGCTACGCTG GCCCACCGCC CACCGTGGCC GAGCTGGTGG AGGCCCACAC CAACTTTGGC 
TTCCAGCCTG ACACGGCCCC CCGCAGCCCC AACACTGGGC CCTACCCCAG TGAGCAGGCC 
CTGCCCATCC CAGGCACCCC GCCCCCCAAC TATGACTCCC TGCGTCTGCA GCCGCTGGAC 
GTCATCGAGT CTGACAGTGA GGGTGATGCC ATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SCNN1B ( XM_011545914.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011544216.1 Homo sapiens sodium channel epithelial 1 subunit beta (SCNN1B), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu60388
Clone ID Related Accession (Same CDS sequence)	XM_011545914.1
Accession Version	XM_011545914.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1941bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	amiloride-sensitive sodium channel subunit beta isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000016.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACTGTGG GTGCCACTAT GCACGTGAAG AAGTACCTGC TGAAGGGCCT GCATCGGCTG 
CAGAAGGGCC CCGGCTACAC GTACAAGGAG CTGCTGGTGT GGTACTGCGA CAACACCAAC 
ACCCACGGCC CCAAGCGCAT CATCTGTGAG GGGCCCAAGA AGAAAGCCAT GTGGTTCCTG 
CTCACCCTGC TCTTCGCCGC CCTCGTCTGC TGGCAGTGGG GCATCTTCAT CAGGACCTAC 
TTGAGCTGGG AGGTCAGCGT CTCCCTCTCC GTAGGCTTCA AGACCATGGA CTTCCCTGCC 
GTCACCATCT GCAATGCTAG CCCCTTCAAG TATTCCAAAA TCAAGCATTT GCTGAAGGAC 
CTGGATGAGC TGATGGAAGC TGTCCTGGAG AGAATCCTGG CTCCTGAGCT AAGCCATGCC 
AATGCCACCA GGAACCTGAA CTTCTCCATC TGGAACCACA CACCCCTGGT CCTTATTGAT 
GAACGGAACC CCCACCACCC CATGGTCCTT GATCTCTTTG GAGACAACCA CAATGGCTTA 
ACAAGCAGCT CAGCATCAGA AAAGATCTGT AATGCCCACG GGTGCAAAAT GGCCATGAGA 
CTATGTAGCC TCAACAGGAC CCAGTGTACC TTCCGGAACT TCACCAGTGC TACCCAGGCA 
TTGACAGAGT GGTACATCCT GCAGGCCACC AACATCTTTG CACAGGTGCC ACAGCAGGAG 
CTAGTAGAGA TGAGCTACCC CGGCGAGCAG ATGATCCTGG CCTGCCTATT CGGAGCTGAG 
CCCTGCAACT ACCGGAACTT CACGTCCATC TTCTACCCTC ACTATGGCAA CTGTTACATC 
TTCAACTGGG GCATGACAGA GAAGGCACTT CCTTCGGCCA ACCCTGGAAC TGAATTCGGC 
CTGAAGTTGA TCCTGGACAT AGGCCAGGAA GACTACGTCC CCTTCCTTGC GTCCACGGCC 
GGGGTCAGGC TGATGCTTCA CGAGCAGAGG TCATACCCCT TCATCAGAGA TGAGGGCATC 
TACGCCATGT CGGGGACAGA GACGTCCATC GGGGTACTCG TGGACAAGCT TCAGCGCATG 
GGGGAGCCCT ACAGCCCGTG CACCGTGAAT GGTTCTGAGG TCCCCGTCCA AAACTTCTAC 
AGTGACTACA ACACGACCTA CTCCATCCAG GCCTGTCTTC GCTCCTGCTT CCAAGACCAC 
ATGATCCGTA ACTGCAACTG TGGCCACTAC CTGTACCCAC TGCCCCGTGG GGAGAAATAC 
TGCAACAACC GGGACTTCCC AGACTGGGCC CATTGCTACT CAGATCTACA GATGAGCGTG 
GCGCAGAGAG AGACCTGCAT TGGCATGTGC AAGGAGTCCT GCAATGACAC CCAGTACAAG 
ATGACCATCT CCATGGCTGA CTGGCCTTCT GAGGCCTCCG AGGACTGGAT TTTCCACGTC 
TTGTCTCAGG AGCGGGACCA AAGCACCAAT ATCACCCTGA GCAGGAAGGG AATTGTCAAG 
CTCAACATCT ACTTCCAAGA ATTTAACTAT CGCACCATTG AAGAATCAGC AGCCAATAAC 
ATCGTCTGGC TGCTCTCGAA TCTGGGTGGC CAGTTTGGCT TCTGGATGGG GGGCTCTGTG 
CTGTGCCTCA TCGAGTTTGG GGAGATCATC ATCGACTTTG TGTGGATCAC CATCATCAAG 
CTGGTGGCCT TGGCCAAGAG CCTACGGCAG CGGCGAGCCC AAGCCAGCTA CGCTGGCCCA 
CCGCCCACCG TGGCCGAGCT GGTGGAGGCC CACACCAACT TTGGCTTCCA GCCTGACACG 
GCCCCCCGCA GCCCCAACAC TGGGCCCTAC CCCAGTGAGC AGGCCCTGCC CATCCCAGGC 
ACCCCGCCCC CCAACTATGA CTCCCTGCGT CTGCAGCCGC TGGACGTCAT CGAGTCTGAC 
AGTGAGGGTG ATGCCATCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011544216.1
CDS	7..1947
Translation	MTVGATMHVKKYLLKGLHRLQKGPGYTYKELLVWYCDNTNTHGPKRIICEGPKKKAMWFLLTLLFAALVCWQWGIFIRTYLSWEVSVSLSVGFKTMDFPAVTICNASPFKYSKIKHLLKDLDELMEAVLERILAPELSHANATRNLNFSIWNHTPLVLIDERNPHHPMVLDLFGDNHNGLTSSSASEKICNAHGCKMAMRLCSLNRTQCTFRNFTSATQALTEWYILQATNIFAQVPQQELVEMSYPGEQMILACLFGAEPCNYRNFTSIFYPHYGNCYIFNWGMTEKALPSANPGTEFGLKLILDIGQEDYVPFLASTAGVRLMLHEQRSYPFIRDEGIYAMSGTETSIGVLVDKLQRMGEPYSPCTVNGSEVPVQNFYSDYNTTYSIQACLRSCFQDHMIRNCNCGHYLYPLPRGEKYCNNRDFPDWAHCYSDLQMSVAQRETCIGMCKESCNDTQYKMTISMADWPSEASEDWIFHVLSQERDQSTNITLSRKGIVKLNIYFQEFNYRTIEESAANNIVWLLSNLGGQFGFWMGGSVLCLIEFGEIIIDFVWITIIKLVALAKSLRQRRAQASYAGPPPTVAELVEAHTNFGFQPDTAPRSPNTGPYPSEQALPIPGTPPPNYDSLRLQPLDVIESDSEGDAI

Target ORF information:

RefSeq Version	XM_011545914.1
Organism	Homo sapiens(human)
Definition	Homo sapiens sodium channel epithelial 1 subunit beta (SCNN1B), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011545914.1

ORF Insert Sequence:

ATGACTGTGG GTGCCACTAT GCACGTGAAG AAGTACCTGC TGAAGGGCCT GCATCGGCTG 
CAGAAGGGCC CCGGCTACAC GTACAAGGAG CTGCTGGTGT GGTACTGCGA CAACACCAAC 
ACCCACGGCC CCAAGCGCAT CATCTGTGAG GGGCCCAAGA AGAAAGCCAT GTGGTTCCTG 
CTCACCCTGC TCTTCGCCGC CCTCGTCTGC TGGCAGTGGG GCATCTTCAT CAGGACCTAC 
TTGAGCTGGG AGGTCAGCGT CTCCCTCTCC GTAGGCTTCA AGACCATGGA CTTCCCTGCC 
GTCACCATCT GCAATGCTAG CCCCTTCAAG TATTCCAAAA TCAAGCATTT GCTGAAGGAC 
CTGGATGAGC TGATGGAAGC TGTCCTGGAG AGAATCCTGG CTCCTGAGCT AAGCCATGCC 
AATGCCACCA GGAACCTGAA CTTCTCCATC TGGAACCACA CACCCCTGGT CCTTATTGAT 
GAACGGAACC CCCACCACCC CATGGTCCTT GATCTCTTTG GAGACAACCA CAATGGCTTA 
ACAAGCAGCT CAGCATCAGA AAAGATCTGT AATGCCCACG GGTGCAAAAT GGCCATGAGA 
CTATGTAGCC TCAACAGGAC CCAGTGTACC TTCCGGAACT TCACCAGTGC TACCCAGGCA 
TTGACAGAGT GGTACATCCT GCAGGCCACC AACATCTTTG CACAGGTGCC ACAGCAGGAG 
CTAGTAGAGA TGAGCTACCC CGGCGAGCAG ATGATCCTGG CCTGCCTATT CGGAGCTGAG 
CCCTGCAACT ACCGGAACTT CACGTCCATC TTCTACCCTC ACTATGGCAA CTGTTACATC 
TTCAACTGGG GCATGACAGA GAAGGCACTT CCTTCGGCCA ACCCTGGAAC TGAATTCGGC 
CTGAAGTTGA TCCTGGACAT AGGCCAGGAA GACTACGTCC CCTTCCTTGC GTCCACGGCC 
GGGGTCAGGC TGATGCTTCA CGAGCAGAGG TCATACCCCT TCATCAGAGA TGAGGGCATC 
TACGCCATGT CGGGGACAGA GACGTCCATC GGGGTACTCG TGGACAAGCT TCAGCGCATG 
GGGGAGCCCT ACAGCCCGTG CACCGTGAAT GGTTCTGAGG TCCCCGTCCA AAACTTCTAC 
AGTGACTACA ACACGACCTA CTCCATCCAG GCCTGTCTTC GCTCCTGCTT CCAAGACCAC 
ATGATCCGTA ACTGCAACTG TGGCCACTAC CTGTACCCAC TGCCCCGTGG GGAGAAATAC 
TGCAACAACC GGGACTTCCC AGACTGGGCC CATTGCTACT CAGATCTACA GATGAGCGTG 
GCGCAGAGAG AGACCTGCAT TGGCATGTGC AAGGAGTCCT GCAATGACAC CCAGTACAAG 
ATGACCATCT CCATGGCTGA CTGGCCTTCT GAGGCCTCCG AGGACTGGAT TTTCCACGTC 
TTGTCTCAGG AGCGGGACCA AAGCACCAAT ATCACCCTGA GCAGGAAGGG AATTGTCAAG 
CTCAACATCT ACTTCCAAGA ATTTAACTAT CGCACCATTG AAGAATCAGC AGCCAATAAC 
ATCGTCTGGC TGCTCTCGAA TCTGGGTGGC CAGTTTGGCT TCTGGATGGG GGGCTCTGTG 
CTGTGCCTCA TCGAGTTTGG GGAGATCATC ATCGACTTTG TGTGGATCAC CATCATCAAG 
CTGGTGGCCT TGGCCAAGAG CCTACGGCAG CGGCGAGCCC AAGCCAGCTA CGCTGGCCCA 
CCGCCCACCG TGGCCGAGCT GGTGGAGGCC CACACCAACT TTGGCTTCCA GCCTGACACG 
GCCCCCCGCA GCCCCAACAC TGGGCCCTAC CCCAGTGAGC AGGCCCTGCC CATCCCAGGC 
ACCCCGCCCC CCAACTATGA CTCCCTGCGT CTGCAGCCGC TGGACGTCAT CGAGTCTGAC 
AGTGAGGGTG ATGCCATCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SCNN1B ( XM_017023525.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016879014.1 Homo sapiens sodium channel epithelial 1 subunit beta (SCNN1B), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu86191
Clone ID Related Accession (Same CDS sequence)	XM_017023525.1
Accession Version	XM_017023525.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1980bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	amiloride-sensitive sodium channel subunit beta isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000016.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTGAAGC AATCCTGGAC TCAGCAACAT CAGGAAACTA CTCTCACAGG TGCCACTATG 
CACGTGAAGA AGTACCTGCT GAAGGGCCTG CATCGGCTGC AGAAGGGCCC CGGCTACACG 
TACAAGGAGC TGCTGGTGTG GTACTGCGAC AACACCAACA CCCACGGCCC CAAGCGCATC 
ATCTGTGAGG GGCCCAAGAA GAAAGCCATG TGGTTCCTGC TCACCCTGCT CTTCGCCGCC 
CTCGTCTGCT GGCAGTGGGG CATCTTCATC AGGACCTACT TGAGCTGGGA GGTCAGCGTC 
TCCCTCTCCG TAGGCTTCAA GACCATGGAC TTCCCTGCCG TCACCATCTG CAATGCTAGC 
CCCTTCAAGT ATTCCAAAAT CAAGCATTTG CTGAAGGACC TGGATGAGCT GATGGAAGCT 
GTCCTGGAGA GAATCCTGGC TCCTGAGCTA AGCCATGCCA ATGCCACCAG GAACCTGAAC 
TTCTCCATCT GGAACCACAC ACCCCTGGTC CTTATTGATG AACGGAACCC CCACCACCCC 
ATGGTCCTTG ATCTCTTTGG AGACAACCAC AATGGCTTAA CAAGCAGCTC AGCATCAGAA 
AAGATCTGTA ATGCCCACGG GTGCAAAATG GCCATGAGAC TATGTAGCCT CAACAGGACC 
CAGTGTACCT TCCGGAACTT CACCAGTGCT ACCCAGGCAT TGACAGAGTG GTACATCCTG 
CAGGCCACCA ACATCTTTGC ACAGGTGCCA CAGCAGGAGC TAGTAGAGAT GAGCTACCCC 
GGCGAGCAGA TGATCCTGGC CTGCCTATTC GGAGCTGAGC CCTGCAACTA CCGGAACTTC 
ACGTCCATCT TCTACCCTCA CTATGGCAAC TGTTACATCT TCAACTGGGG CATGACAGAG 
AAGGCACTTC CTTCGGCCAA CCCTGGAACT GAATTCGGCC TGAAGTTGAT CCTGGACATA 
GGCCAGGAAG ACTACGTCCC CTTCCTTGCG TCCACGGCCG GGGTCAGGCT GATGCTTCAC 
GAGCAGAGGT CATACCCCTT CATCAGAGAT GAGGGCATCT ACGCCATGTC GGGGACAGAG 
ACGTCCATCG GGGTACTCGT GGACAAGCTT CAGCGCATGG GGGAGCCCTA CAGCCCGTGC 
ACCGTGAATG GTTCTGAGGT CCCCGTCCAA AACTTCTACA GTGACTACAA CACGACCTAC 
TCCATCCAGG CCTGTCTTCG CTCCTGCTTC CAAGACCACA TGATCCGTAA CTGCAACTGT 
GGCCACTACC TGTACCCACT GCCCCGTGGG GAGAAATACT GCAACAACCG GGACTTCCCA 
GACTGGGCCC ATTGCTACTC AGATCTACAG ATGAGCGTGG CGCAGAGAGA GACCTGCATT 
GGCATGTGCA AGGAGTCCTG CAATGACACC CAGTACAAGA TGACCATCTC CATGGCTGAC 
TGGCCTTCTG AGGCCTCCGA GGACTGGATT TTCCACGTCT TGTCTCAGGA GCGGGACCAA 
AGCACCAATA TCACCCTGAG CAGGAAGGGA ATTGTCAAGC TCAACATCTA CTTCCAAGAA 
TTTAACTATC GCACCATTGA AGAATCAGCA GCCAATAACA TCGTCTGGCT GCTCTCGAAT 
CTGGGTGGCC AGTTTGGCTT CTGGATGGGG GGCTCTGTGC TGTGCCTCAT CGAGTTTGGG 
GAGATCATCA TCGACTTTGT GTGGATCACC ATCATCAAGC TGGTGGCCTT GGCCAAGAGC 
CTACGGCAGC GGCGAGCCCA AGCCAGCTAC GCTGGCCCAC CGCCCACCGT GGCCGAGCTG 
GTGGAGGCCC ACACCAACTT TGGCTTCCAG CCTGACACGG CCCCCCGCAG CCCCAACACT 
GGGCCCTACC CCAGTGAGCA GGCCCTGCCC ATCCCAGGCA CCCCGCCCCC CAACTATGAC 
TCCCTGCGTC TGCAGCCGCT GGACGTCATC GAGTCTGACA GTGAGGGTGA TGCCATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016879014.1
CDS	130..2109
Translation	MVKQSWTQQHQETTLTGATMHVKKYLLKGLHRLQKGPGYTYKELLVWYCDNTNTHGPKRIICEGPKKKAMWFLLTLLFAALVCWQWGIFIRTYLSWEVSVSLSVGFKTMDFPAVTICNASPFKYSKIKHLLKDLDELMEAVLERILAPELSHANATRNLNFSIWNHTPLVLIDERNPHHPMVLDLFGDNHNGLTSSSASEKICNAHGCKMAMRLCSLNRTQCTFRNFTSATQALTEWYILQATNIFAQVPQQELVEMSYPGEQMILACLFGAEPCNYRNFTSIFYPHYGNCYIFNWGMTEKALPSANPGTEFGLKLILDIGQEDYVPFLASTAGVRLMLHEQRSYPFIRDEGIYAMSGTETSIGVLVDKLQRMGEPYSPCTVNGSEVPVQNFYSDYNTTYSIQACLRSCFQDHMIRNCNCGHYLYPLPRGEKYCNNRDFPDWAHCYSDLQMSVAQRETCIGMCKESCNDTQYKMTISMADWPSEASEDWIFHVLSQERDQSTNITLSRKGIVKLNIYFQEFNYRTIEESAANNIVWLLSNLGGQFGFWMGGSVLCLIEFGEIIIDFVWITIIKLVALAKSLRQRRAQASYAGPPPTVAELVEAHTNFGFQPDTAPRSPNTGPYPSEQALPIPGTPPPNYDSLRLQPLDVIESDSEGDAI

Target ORF information:

RefSeq Version	XM_017023525.1
Organism	Homo sapiens(human)
Definition	Homo sapiens sodium channel epithelial 1 subunit beta (SCNN1B), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017023525.1

ORF Insert Sequence:

ATGGTGAAGC AATCCTGGAC TCAGCAACAT CAGGAAACTA CTCTCACAGG TGCCACTATG 
CACGTGAAGA AGTACCTGCT GAAGGGCCTG CATCGGCTGC AGAAGGGCCC CGGCTACACG 
TACAAGGAGC TGCTGGTGTG GTACTGCGAC AACACCAACA CCCACGGCCC CAAGCGCATC 
ATCTGTGAGG GGCCCAAGAA GAAAGCCATG TGGTTCCTGC TCACCCTGCT CTTCGCCGCC 
CTCGTCTGCT GGCAGTGGGG CATCTTCATC AGGACCTACT TGAGCTGGGA GGTCAGCGTC 
TCCCTCTCCG TAGGCTTCAA GACCATGGAC TTCCCTGCCG TCACCATCTG CAATGCTAGC 
CCCTTCAAGT ATTCCAAAAT CAAGCATTTG CTGAAGGACC TGGATGAGCT GATGGAAGCT 
GTCCTGGAGA GAATCCTGGC TCCTGAGCTA AGCCATGCCA ATGCCACCAG GAACCTGAAC 
TTCTCCATCT GGAACCACAC ACCCCTGGTC CTTATTGATG AACGGAACCC CCACCACCCC 
ATGGTCCTTG ATCTCTTTGG AGACAACCAC AATGGCTTAA CAAGCAGCTC AGCATCAGAA 
AAGATCTGTA ATGCCCACGG GTGCAAAATG GCCATGAGAC TATGTAGCCT CAACAGGACC 
CAGTGTACCT TCCGGAACTT CACCAGTGCT ACCCAGGCAT TGACAGAGTG GTACATCCTG 
CAGGCCACCA ACATCTTTGC ACAGGTGCCA CAGCAGGAGC TAGTAGAGAT GAGCTACCCC 
GGCGAGCAGA TGATCCTGGC CTGCCTATTC GGAGCTGAGC CCTGCAACTA CCGGAACTTC 
ACGTCCATCT TCTACCCTCA CTATGGCAAC TGTTACATCT TCAACTGGGG CATGACAGAG 
AAGGCACTTC CTTCGGCCAA CCCTGGAACT GAATTCGGCC TGAAGTTGAT CCTGGACATA 
GGCCAGGAAG ACTACGTCCC CTTCCTTGCG TCCACGGCCG GGGTCAGGCT GATGCTTCAC 
GAGCAGAGGT CATACCCCTT CATCAGAGAT GAGGGCATCT ACGCCATGTC GGGGACAGAG 
ACGTCCATCG GGGTACTCGT GGACAAGCTT CAGCGCATGG GGGAGCCCTA CAGCCCGTGC 
ACCGTGAATG GTTCTGAGGT CCCCGTCCAA AACTTCTACA GTGACTACAA CACGACCTAC 
TCCATCCAGG CCTGTCTTCG CTCCTGCTTC CAAGACCACA TGATCCGTAA CTGCAACTGT 
GGCCACTACC TGTACCCACT GCCCCGTGGG GAGAAATACT GCAACAACCG GGACTTCCCA 
GACTGGGCCC ATTGCTACTC AGATCTACAG ATGAGCGTGG CGCAGAGAGA GACCTGCATT 
GGCATGTGCA AGGAGTCCTG CAATGACACC CAGTACAAGA TGACCATCTC CATGGCTGAC 
TGGCCTTCTG AGGCCTCCGA GGACTGGATT TTCCACGTCT TGTCTCAGGA GCGGGACCAA 
AGCACCAATA TCACCCTGAG CAGGAAGGGA ATTGTCAAGC TCAACATCTA CTTCCAAGAA 
TTTAACTATC GCACCATTGA AGAATCAGCA GCCAATAACA TCGTCTGGCT GCTCTCGAAT 
CTGGGTGGCC AGTTTGGCTT CTGGATGGGG GGCTCTGTGC TGTGCCTCAT CGAGTTTGGG 
GAGATCATCA TCGACTTTGT GTGGATCACC ATCATCAAGC TGGTGGCCTT GGCCAAGAGC 
CTACGGCAGC GGCGAGCCCA AGCCAGCTAC GCTGGCCCAC CGCCCACCGT GGCCGAGCTG 
GTGGAGGCCC ACACCAACTT TGGCTTCCAG CCTGACACGG CCCCCCGCAG CCCCAACACT 
GGGCCCTACC CCAGTGAGCA GGCCCTGCCC ATCCCAGGCA CCCCGCCCCC CAACTATGAC 
TCCCTGCGTC TGCAGCCGCT GGACGTCATC GAGTCTGACA GTGAGGGTGA TGCCATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SCNN1B ( XM_017023526.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016879015.1 Homo sapiens sodium channel epithelial 1 subunit beta (SCNN1B), transcript variant X4, mRNA.

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CloneID	OHu86192
Clone ID Related Accession (Same CDS sequence)	XM_017023526.1
Accession Version	XM_017023526.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1872bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	amiloride-sensitive sodium channel subunit beta isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000016.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTGAAGC AATCCTGGAC TCAGCAACAT CAGGAAACTA CTCTCACAGG TGCCACTATG 
CACGTGAAGA AGTACCTGCT GAAGGGCCTG CATCGGCTGC AGAAGGGCCC CGGCTACACG 
TACAAGGAGC TGCTGGTGTG GTACTGCGAC AACACCAACA CCCACGGCCC CAAGCGCATC 
ATCTGTGAGG GGCCCAAGAA GAAAGCCATG TGGTTCCTGC TCACCCTGCT CTTCGCCGCC 
CTCGTCTGCT GGCAGTGGGG CATCTTCATC AGGACCTACT TGAGCTGGGA GGTCAGCGTC 
TCCCTCTCCG TAGGCTTCAA GACCATGGAC TTCCCTGCCG TCACCATCTG CAATGCTAGC 
CCCTTCAAGT ATTCCAAAAT CAAGCATTTG CTGAAGGACC TGGATGAGCT GATGGAAGCT 
GTCCTGGAGA GAATCCTGGC TCCTGAGCTA AGCCATGCCA ATGCCACCAG GAACCTGAAC 
TTCTCCATCT GGAACCACAC ACCCCTGGTC CTTATTGATG AACGGAACCC CCACCACCCC 
ATGGTCCTTG ATCTCTTTGG AGACAACCAC AATGGCTTAA CAAGCAGCTC AGCATCAGAA 
AAGATCTGTA ATGCCCACGG GTGCAAAATG GCCATGAGAC TATGTAGCCT CAACAGGACC 
CAGTGTACCT TCCGGAACTT CACCAGTGCT ACCCAGGCAT TGACAGAGTG GTACATCCTG 
CAGGCCACCA ACATCTTTGC ACAGGTGCCA CAGCAGGAGC TAGTAGAGAT GAGCTACCCC 
GGCGAGCAGA TGATCCTGGC CTGCCTATTC GGAGCTGAGC CCTGCAACTA CCGGAACTTC 
ACGTCCATCT TCTACCCTCA CTATGGCAAC TGTTACATCT TCAACTGGGG CATGACAGAG 
AAGGCACTTC CTTCGGCCAA CCCTGGAACT GAATTCGGCC TGAAGTTGAT CCTGGACATA 
GGCCAGGAAG ACTACGTCCC CTTCCTTGCG TCCACGGCCG GGGTCAGGCT GATGCTTCAC 
GAGCAGAGGT CATACCCCTT CATCAGAGAT GAGGGCATCT ACGCCATGTC GGGGACAGAG 
ACGTCCATCG GGGTACTCGT GGCCTGTCTT CGCTCCTGCT TCCAAGACCA CATGATCCGT 
AACTGCAACT GTGGCCACTA CCTGTACCCA CTGCCCCGTG GGGAGAAATA CTGCAACAAC 
CGGGACTTCC CAGACTGGGC CCATTGCTAC TCAGATCTAC AGATGAGCGT GGCGCAGAGA 
GAGACCTGCA TTGGCATGTG CAAGGAGTCC TGCAATGACA CCCAGTACAA GATGACCATC 
TCCATGGCTG ACTGGCCTTC TGAGGCCTCC GAGGACTGGA TTTTCCACGT CTTGTCTCAG 
GAGCGGGACC AAAGCACCAA TATCACCCTG AGCAGGAAGG GAATTGTCAA GCTCAACATC 
TACTTCCAAG AATTTAACTA TCGCACCATT GAAGAATCAG CAGCCAATAA CATCGTCTGG 
CTGCTCTCGA ATCTGGGTGG CCAGTTTGGC TTCTGGATGG GGGGCTCTGT GCTGTGCCTC 
ATCGAGTTTG GGGAGATCAT CATCGACTTT GTGTGGATCA CCATCATCAA GCTGGTGGCC 
TTGGCCAAGA GCCTACGGCA GCGGCGAGCC CAAGCCAGCT ACGCTGGCCC ACCGCCCACC 
GTGGCCGAGC TGGTGGAGGC CCACACCAAC TTTGGCTTCC AGCCTGACAC GGCCCCCCGC 
AGCCCCAACA CTGGGCCCTA CCCCAGTGAG CAGGCCCTGC CCATCCCAGG CACCCCGCCC 
CCCAACTATG ACTCCCTGCG TCTGCAGCCG CTGGACGTCA TCGAGTCTGA CAGTGAGGGT 
GATGCCATCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016879015.1
CDS	130..2001
Translation	MVKQSWTQQHQETTLTGATMHVKKYLLKGLHRLQKGPGYTYKELLVWYCDNTNTHGPKRIICEGPKKKAMWFLLTLLFAALVCWQWGIFIRTYLSWEVSVSLSVGFKTMDFPAVTICNASPFKYSKIKHLLKDLDELMEAVLERILAPELSHANATRNLNFSIWNHTPLVLIDERNPHHPMVLDLFGDNHNGLTSSSASEKICNAHGCKMAMRLCSLNRTQCTFRNFTSATQALTEWYILQATNIFAQVPQQELVEMSYPGEQMILACLFGAEPCNYRNFTSIFYPHYGNCYIFNWGMTEKALPSANPGTEFGLKLILDIGQEDYVPFLASTAGVRLMLHEQRSYPFIRDEGIYAMSGTETSIGVLVACLRSCFQDHMIRNCNCGHYLYPLPRGEKYCNNRDFPDWAHCYSDLQMSVAQRETCIGMCKESCNDTQYKMTISMADWPSEASEDWIFHVLSQERDQSTNITLSRKGIVKLNIYFQEFNYRTIEESAANNIVWLLSNLGGQFGFWMGGSVLCLIEFGEIIIDFVWITIIKLVALAKSLRQRRAQASYAGPPPTVAELVEAHTNFGFQPDTAPRSPNTGPYPSEQALPIPGTPPPNYDSLRLQPLDVIESDSEGDAI

Target ORF information:

RefSeq Version	XM_017023526.1
Organism	Homo sapiens(human)
Definition	Homo sapiens sodium channel epithelial 1 subunit beta (SCNN1B), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017023526.1

ORF Insert Sequence:

ATGGTGAAGC AATCCTGGAC TCAGCAACAT CAGGAAACTA CTCTCACAGG TGCCACTATG 
CACGTGAAGA AGTACCTGCT GAAGGGCCTG CATCGGCTGC AGAAGGGCCC CGGCTACACG 
TACAAGGAGC TGCTGGTGTG GTACTGCGAC AACACCAACA CCCACGGCCC CAAGCGCATC 
ATCTGTGAGG GGCCCAAGAA GAAAGCCATG TGGTTCCTGC TCACCCTGCT CTTCGCCGCC 
CTCGTCTGCT GGCAGTGGGG CATCTTCATC AGGACCTACT TGAGCTGGGA GGTCAGCGTC 
TCCCTCTCCG TAGGCTTCAA GACCATGGAC TTCCCTGCCG TCACCATCTG CAATGCTAGC 
CCCTTCAAGT ATTCCAAAAT CAAGCATTTG CTGAAGGACC TGGATGAGCT GATGGAAGCT 
GTCCTGGAGA GAATCCTGGC TCCTGAGCTA AGCCATGCCA ATGCCACCAG GAACCTGAAC 
TTCTCCATCT GGAACCACAC ACCCCTGGTC CTTATTGATG AACGGAACCC CCACCACCCC 
ATGGTCCTTG ATCTCTTTGG AGACAACCAC AATGGCTTAA CAAGCAGCTC AGCATCAGAA 
AAGATCTGTA ATGCCCACGG GTGCAAAATG GCCATGAGAC TATGTAGCCT CAACAGGACC 
CAGTGTACCT TCCGGAACTT CACCAGTGCT ACCCAGGCAT TGACAGAGTG GTACATCCTG 
CAGGCCACCA ACATCTTTGC ACAGGTGCCA CAGCAGGAGC TAGTAGAGAT GAGCTACCCC 
GGCGAGCAGA TGATCCTGGC CTGCCTATTC GGAGCTGAGC CCTGCAACTA CCGGAACTTC 
ACGTCCATCT TCTACCCTCA CTATGGCAAC TGTTACATCT TCAACTGGGG CATGACAGAG 
AAGGCACTTC CTTCGGCCAA CCCTGGAACT GAATTCGGCC TGAAGTTGAT CCTGGACATA 
GGCCAGGAAG ACTACGTCCC CTTCCTTGCG TCCACGGCCG GGGTCAGGCT GATGCTTCAC 
GAGCAGAGGT CATACCCCTT CATCAGAGAT GAGGGCATCT ACGCCATGTC GGGGACAGAG 
ACGTCCATCG GGGTACTCGT GGCCTGTCTT CGCTCCTGCT TCCAAGACCA CATGATCCGT 
AACTGCAACT GTGGCCACTA CCTGTACCCA CTGCCCCGTG GGGAGAAATA CTGCAACAAC 
CGGGACTTCC CAGACTGGGC CCATTGCTAC TCAGATCTAC AGATGAGCGT GGCGCAGAGA 
GAGACCTGCA TTGGCATGTG CAAGGAGTCC TGCAATGACA CCCAGTACAA GATGACCATC 
TCCATGGCTG ACTGGCCTTC TGAGGCCTCC GAGGACTGGA TTTTCCACGT CTTGTCTCAG 
GAGCGGGACC AAAGCACCAA TATCACCCTG AGCAGGAAGG GAATTGTCAA GCTCAACATC 
TACTTCCAAG AATTTAACTA TCGCACCATT GAAGAATCAG CAGCCAATAA CATCGTCTGG 
CTGCTCTCGA ATCTGGGTGG CCAGTTTGGC TTCTGGATGG GGGGCTCTGT GCTGTGCCTC 
ATCGAGTTTG GGGAGATCAT CATCGACTTT GTGTGGATCA CCATCATCAA GCTGGTGGCC 
TTGGCCAAGA GCCTACGGCA GCGGCGAGCC CAAGCCAGCT ACGCTGGCCC ACCGCCCACC 
GTGGCCGAGC TGGTGGAGGC CCACACCAAC TTTGGCTTCC AGCCTGACAC GGCCCCCCGC 
AGCCCCAACA CTGGGCCCTA CCCCAGTGAG CAGGCCCTGC CCATCCCAGG CACCCCGCCC 
CCCAACTATG ACTCCCTGCG TCTGCAGCCG CTGGACGTCA TCGAGTCTGA CAGTGAGGGT 
GATGCCATCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Mapping allosteric linkage to channel gating of extracellular domains in the human epithelial sodium channel.
The Journal of biological chemistry(2018 Jan)
Shobair M,Popov KI,Dang YL,He H,Stutts MJ,Dokholyan NV

The Epithelial Sodium Channel Is a Modifier of the Long-Term Nonprogressive Phenotype Associated with F508del CFTR Mutations.
American journal of respiratory cell and molecular biology57(6)711-720(2017 Dec)
Agrawal PB,Wang R,Li HL,Schmitz-Abe K,Simone-Roach C,Chen J,Shi J,Louie T,Sheng S,Towne MC,Brainson CF,Matthay MA,Kim CF,Bamshad M,Emond MJ,Gerard NP,Kleyman TR,Gerard C

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SCNN1B cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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