Pdp2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Pdp2
Entrez Gene ID	246311
Full Name	pyruvate dehyrogenase phosphatase catalytic subunit 2
General protein information	Preferred Names pyruvate dehyrogenase phosphatase catalytic subunit 2 Names [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial pyruvate dehydrogenase [acetyl-transferring]-phosphatase 2, mitochondrial PDP 2 PDPC 2 pyruvate dehydrogenase phosphatase isoenzyme 2 pyruvate dehydrogenase phosphatase, catalytic subunit 2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 19 Map Location: 19p14
Summary	catalyzes the dephosphorylation and reactivation of the pyruvate dehydrogenase complex; plays a role in carbohydrate utilization [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006255048.3	XP_006255110.1	pyruvate dehydrogenase [acetyl-transferring]-phosphatase 2, mitochondrial isoform X1
NM_145091.4	NP_659559.2	[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	PDP2	XP_511016.2
	PDP2	XP_002802573.1
Canis lupus familiaris (dog)	PDP2	XP_005620923.1
Bos taurus (cattle)	PDP2	XP_002694852.1
Saccharomyces cerevisiae (baker's yeast)	PTC5	NP_014733.1
Kluyveromyces lactis	KLLA0C13706g	XP_452812.1
Xenopus tropicalis (tropical clawed frog)	pdp2	XP_002942040.1
Mus musculus (house mouse)	Pdp2	NP_001019777.1
Gallus gallus (chicken)	PDP2	XP_004944303.1
Magnaporthe oryzae (rice blast fungus)	MGG_03154	XP_003716839.1
Neurospora crassa	NCU01767	XP_957190.2
Danio rerio (zebrafish)	pdp2	NP_571700.1
Eremothecium gossypii	AGOS_ACL083C	NP_983321.1
Homo sapiens (human)	PDP2	NP_065837.1
Rattus norvegicus (Norway rat)	Pdp2	NP_659559.2
Schizosaccharomyces pombe (fission yeast)	SPAC10F6.17c	NP_593268.2

Gene Ontology
Bibliography

Related articles in PubMed

Ppm1E is an in cellulo AMP-activated protein kinase phosphatase.
Voss M, Paterson J, Kelsall IR, Mart?n-Granados C, Hastie CJ, Peggie MW, Cohen PT
Cellular signalling23(1)114-24(2011 Jan)

Pyruvate dehydrogenase kinase regulatory mechanisms and inhibition in treating diabetes, heart ischemia, and cancer.
Roche TE, Hiromasa Y
Cellular and molecular life sciences : CMLS64(7-8)830-49(2007 Apr)

Starvation and diabetes reduce the amount of pyruvate dehydrogenase phosphatase in rat heart and kidney.
Huang B, Wu P, Popov KM, Harris RA
Diabetes52(6)1371-6(2003 Jun)

Isoenzymes of pyruvate dehydrogenase phosphatase. DNA-derived amino acid sequences, expression, and regulation.
Huang B, Gudi R, Wu P, Harris RA, Hamilton J, Popov KM
The Journal of biological chemistry273(28)17680-8(1998 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Starvation and diabetes reduce the amount of this enzyme in heart and kidney.
Title: Starvation and diabetes reduce the amount of pyruvate dehydrogenase phosphatase in rat heart and kidney.

The following Pdp2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pdp2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa02559	NM_145091.4 Latest version!	Rattus norvegicus pyruvate dehyrogenase phosphatase catalytic subunit 2 (Pdp2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa02559	XM_006255048.3 Latest version!	Rattus norvegicus pyruvate dehyrogenase phosphatase catalytic subunit 2 (Pdp2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Pdp2 ( NM_145091.4 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_659559.2 Rattus norvegicus pyruvate dehyrogenase phosphatase catalytic subunit 2 (Pdp2), mRNA.

Price & Availability↑

CloneID	ORa02559
Clone ID Related Accession (Same CDS sequence)	XM_006255048.3 , NM_145091.4
Accession Version	NM_145091.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1593bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Rattus norvegicus(Norway rat)
Product	[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC072485.1. On Oct 26, 2007 this sequence version replaced NM_145091.3. ##Evidence-Data-START## Transcript exon combination :: CK357780.1, FM062313.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCAAGTA CTGCGTCCTA CCGGATCTTC AATTTTGCAA GGAATCGTAT TGCTGTGTTA 
CGAGGGGGTA GACGCTTGTA CTCCAGGGCA GCCACGAGTA GGAATCAAGT GAAATGGAGG 
CTCTTTTCTC CCGCATCATT GGCCGTGAAC GACAGTTCTC CACATGGTGG CTTTGCTCTG 
CGGAAAGCTT ACAGACACAC ATCAACCGAG GAAGAGGATT TCCACTTGCA GCTCAGCCCC 
GAACAGGTCA GTGACCTGCT CCGAGCTGGC GAGTCATCCC ACAAGGTTCT GGATTTCAAC 
AGCGGAGTTC CAAATTCAGT GTTAAGGTTT GAGAGCAACC AGTTGGCGGC CAATTCCCCA 
GTGGAAGACC GACAAGGTGT GGCTTCCTGC GTGCAGACGA GGGGGACGAT GTTTGGTATT 
TTTGATGGGC ATGGTGGCCA TGCGTGTGCA CAGGCGGTGA GCGAGAGGCT TTTCTATTAC 
ATGGCGGTGT CCCTCATGTC CCATAAGACC TTGGAGCAGA TGGAGGAAGC CATGGAGAAC 
ATGAAGCCTT TGCTGCCCAT CCTGCAGTGG CTCAAGCACC CCGGAGACAG TATTTATAAA 
GATATCACAT CGGTTCATCT GGACCACCTC CGAGTCTATT GGCAGGAACT CCTTGACCTA 
CATATGGAAA CGGGACTAAG CACTGAAGAG GCATTGATGT ACTCCTTCCA GAGACTGGAC 
TCCGACATCT CGCTAGAAAT TCAGGCTCCT CTGGAAGATG AGGTAACGAA GAACTTATCC 
CTCCAGGTTG CTTTTTCTGG GGCGACAGCC TGCATGGCCC ACGTCGACGG AGTTCACCTG 
CACATAGCAA ATGCTGGCGA CTGCCGAGCT ATCCTGGGTG TCCAGGGAGA CAATGGAGCG 
TGGTCATGTT TACCTCTTAC CTGTGACCAC AATGCCTGGA ATGAGGCAGA GCTGTCCCGG 
CTTAAGAGAG AACACCCCGA GTCTGAGGAC AGGACACTCA TCATAGATGA CAGGCTGCTG 
GGTGTCCTCC TACCCTGCAG GGCCTTCGGG GACGTCCAGC TAAAATGGAG TAAAGAGTTG 
CAGCGGAACG TCCTAGAGAG GGGATTTGAT ACCGAGGCCC TCAACATCTA CCAGTTTACC 
CCGCCCCACT ACCACACTCC ACCCTACCTG ACTGCTAAGC CTGAGGTCAC ATACCACAGG 
CTTAGGCCCC AAGATAAGTT CCTCGTGCTG GCCTCAGATG GCCTCTGGGA CATGCTGGAC 
AATGAGGATG TGGTAAGGCT GGTGGTGGGG CACCTGTCCA AGGTCGGTCA CCAGAAGCCA 
GCCCTGGATC AAAGACCAGC CAACCTGGGC CACATGCAGA GTCTGCTGCT GCAGAGGAAA 
GCCAGCGGAC TCCATGCAGC TGACCAGAAT GCAGCCACAC ATCTGATCAG ACATGCCATC 
GGGAGCAACG AGTATGGGGA AATGGAGCCA GAGCGTCTGG CTGCCATGTT GACGCTGCCA 
GAGGATGTGG CCAGGATGTA CCGGGATGAC ATCACTGTCA TGGTGGTGTT TTTTAACTCA 
GAATCAATTG ATACCTATTT TAAGGAGGGT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_659559.2
CDS	128..1720
Translation	MSSTASYRIFNFARNRIAVLRGGRRLYSRAATSRNQVKWRLFSPASLAVNDSSPHGGFALRKAYRHTSTEEEDFHLQLSPEQVSDLLRAGESSHKVLDFNSGVPNSVLRFESNQLAANSPVEDRQGVASCVQTRGTMFGIFDGHGGHACAQAVSERLFYYMAVSLMSHKTLEQMEEAMENMKPLLPILQWLKHPGDSIYKDITSVHLDHLRVYWQELLDLHMETGLSTEEALMYSFQRLDSDISLEIQAPLEDEVTKNLSLQVAFSGATACMAHVDGVHLHIANAGDCRAILGVQGDNGAWSCLPLTCDHNAWNEAELSRLKREHPESEDRTLIIDDRLLGVLLPCRAFGDVQLKWSKELQRNVLERGFDTEALNIYQFTPPHYHTPPYLTAKPEVTYHRLRPQDKFLVLASDGLWDMLDNEDVVRLVVGHLSKVGHQKPALDQRPANLGHMQSLLLQRKASGLHAADQNAATHLIRHAIGSNEYGEMEPERLAAMLTLPEDVARMYRDDITVMVVFFNSESIDTYFKEG

Target ORF information:

RefSeq Version	NM_145091.4
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus pyruvate dehyrogenase phosphatase catalytic subunit 2 (Pdp2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_145091.4

ORF Insert Sequence:

ATGTCAAGTA CTGCGTCCTA CCGGATCTTC AATTTTGCAA GGAATCGTAT TGCTGTGTTA 
CGAGGGGGTA GACGCTTGTA CTCCAGGGCA GCCACGAGTA GGAATCAAGT GAAATGGAGG 
CTCTTTTCTC CCGCATCATT GGCCGTGAAC GACAGTTCTC CACATGGTGG CTTTGCTCTG 
CGGAAAGCTT ACAGACACAC ATCAACCGAG GAAGAGGATT TCCACTTGCA GCTCAGCCCC 
GAACAGGTCA GTGACCTGCT CCGAGCTGGC GAGTCATCCC ACAAGGTTCT GGATTTCAAC 
AGCGGAGTTC CAAATTCAGT GTTAAGGTTT GAGAGCAACC AGTTGGCGGC CAATTCCCCA 
GTGGAAGACC GACAAGGTGT GGCTTCCTGC GTGCAGACGA GGGGGACGAT GTTTGGTATT 
TTTGATGGGC ATGGTGGCCA TGCGTGTGCA CAGGCGGTGA GCGAGAGGCT TTTCTATTAC 
ATGGCGGTGT CCCTCATGTC CCATAAGACC TTGGAGCAGA TGGAGGAAGC CATGGAGAAC 
ATGAAGCCTT TGCTGCCCAT CCTGCAGTGG CTCAAGCACC CCGGAGACAG TATTTATAAA 
GATATCACAT CGGTTCATCT GGACCACCTC CGAGTCTATT GGCAGGAACT CCTTGACCTA 
CATATGGAAA CGGGACTAAG CACTGAAGAG GCATTGATGT ACTCCTTCCA GAGACTGGAC 
TCCGACATCT CGCTAGAAAT TCAGGCTCCT CTGGAAGATG AGGTAACGAA GAACTTATCC 
CTCCAGGTTG CTTTTTCTGG GGCGACAGCC TGCATGGCCC ACGTCGACGG AGTTCACCTG 
CACATAGCAA ATGCTGGCGA CTGCCGAGCT ATCCTGGGTG TCCAGGGAGA CAATGGAGCG 
TGGTCATGTT TACCTCTTAC CTGTGACCAC AATGCCTGGA ATGAGGCAGA GCTGTCCCGG 
CTTAAGAGAG AACACCCCGA GTCTGAGGAC AGGACACTCA TCATAGATGA CAGGCTGCTG 
GGTGTCCTCC TACCCTGCAG GGCCTTCGGG GACGTCCAGC TAAAATGGAG TAAAGAGTTG 
CAGCGGAACG TCCTAGAGAG GGGATTTGAT ACCGAGGCCC TCAACATCTA CCAGTTTACC 
CCGCCCCACT ACCACACTCC ACCCTACCTG ACTGCTAAGC CTGAGGTCAC ATACCACAGG 
CTTAGGCCCC AAGATAAGTT CCTCGTGCTG GCCTCAGATG GCCTCTGGGA CATGCTGGAC 
AATGAGGATG TGGTAAGGCT GGTGGTGGGG CACCTGTCCA AGGTCGGTCA CCAGAAGCCA 
GCCCTGGATC AAAGACCAGC CAACCTGGGC CACATGCAGA GTCTGCTGCT GCAGAGGAAA 
GCCAGCGGAC TCCATGCAGC TGACCAGAAT GCAGCCACAC ATCTGATCAG ACATGCCATC 
GGGAGCAACG AGTATGGGGA AATGGAGCCA GAGCGTCTGG CTGCCATGTT GACGCTGCCA 
GAGGATGTGG CCAGGATGTA CCGGGATGAC ATCACTGTCA TGGTGGTGTT TTTTAACTCA 
GAATCAATTG ATACCTATTT TAAGGAGGGT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pdp2 ( XM_006255048.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006255110.1 Rattus norvegicus pyruvate dehyrogenase phosphatase catalytic subunit 2 (Pdp2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa02559
Clone ID Related Accession (Same CDS sequence)	XM_006255048.3 , NM_145091.4
Accession Version	XM_006255048.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1593bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	pyruvate dehydrogenase [acetyl-transferring]-phosphatase 2, mitochondrial isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005118.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006255048.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCAAGTA CTGCGTCCTA CCGGATCTTC AATTTTGCAA GGAATCGTAT TGCTGTGTTA 
CGAGGGGGTA GACGCTTGTA CTCCAGGGCA GCCACGAGTA GGAATCAAGT GAAATGGAGG 
CTCTTTTCTC CCGCATCATT GGCCGTGAAC GACAGTTCTC CACATGGTGG CTTTGCTCTG 
CGGAAAGCTT ACAGACACAC ATCAACCGAG GAAGAGGATT TCCACTTGCA GCTCAGCCCC 
GAACAGGTCA GTGACCTGCT CCGAGCTGGC GAGTCATCCC ACAAGGTTCT GGATTTCAAC 
AGCGGAGTTC CAAATTCAGT GTTAAGGTTT GAGAGCAACC AGTTGGCGGC CAATTCCCCA 
GTGGAAGACC GACAAGGTGT GGCTTCCTGC GTGCAGACGA GGGGGACGAT GTTTGGTATT 
TTTGATGGGC ATGGTGGCCA TGCGTGTGCA CAGGCGGTGA GCGAGAGGCT TTTCTATTAC 
ATGGCGGTGT CCCTCATGTC CCATAAGACC TTGGAGCAGA TGGAGGAAGC CATGGAGAAC 
ATGAAGCCTT TGCTGCCCAT CCTGCAGTGG CTCAAGCACC CCGGAGACAG TATTTATAAA 
GATATCACAT CGGTTCATCT GGACCACCTC CGAGTCTATT GGCAGGAACT CCTTGACCTA 
CATATGGAAA CGGGACTAAG CACTGAAGAG GCATTGATGT ACTCCTTCCA GAGACTGGAC 
TCCGACATCT CGCTAGAAAT TCAGGCTCCT CTGGAAGATG AGGTAACGAA GAACTTATCC 
CTCCAGGTTG CTTTTTCTGG GGCGACAGCC TGCATGGCCC ACGTCGACGG AGTTCACCTG 
CACATAGCAA ATGCTGGCGA CTGCCGAGCT ATCCTGGGTG TCCAGGGAGA CAATGGAGCG 
TGGTCATGTT TACCTCTTAC CTGTGACCAC AATGCCTGGA ATGAGGCAGA GCTGTCCCGG 
CTTAAGAGAG AACACCCCGA GTCTGAGGAC AGGACACTCA TCATAGATGA CAGGCTGCTG 
GGTGTCCTCC TACCCTGCAG GGCCTTCGGG GACGTCCAGC TAAAATGGAG TAAAGAGTTG 
CAGCGGAACG TCCTAGAGAG GGGATTTGAT ACCGAGGCCC TCAACATCTA CCAGTTTACC 
CCGCCCCACT ACCACACTCC ACCCTACCTG ACTGCTAAGC CTGAGGTCAC ATACCACAGG 
CTTAGGCCCC AAGATAAGTT CCTCGTGCTG GCCTCAGATG GCCTCTGGGA CATGCTGGAC 
AATGAGGATG TGGTAAGGCT GGTGGTGGGG CACCTGTCCA AGGTCGGTCA CCAGAAGCCA 
GCCCTGGATC AAAGACCAGC CAACCTGGGC CACATGCAGA GTCTGCTGCT GCAGAGGAAA 
GCCAGCGGAC TCCATGCAGC TGACCAGAAT GCAGCCACAC ATCTGATCAG ACATGCCATC 
GGGAGCAACG AGTATGGGGA AATGGAGCCA GAGCGTCTGG CTGCCATGTT GACGCTGCCA 
GAGGATGTGG CCAGGATGTA CCGGGATGAC ATCACTGTCA TGGTGGTGTT TTTTAACTCA 
GAATCAATTG ATACCTATTT TAAGGAGGGT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006255110.1
CDS	174..1766
Translation	MSSTASYRIFNFARNRIAVLRGGRRLYSRAATSRNQVKWRLFSPASLAVNDSSPHGGFALRKAYRHTSTEEEDFHLQLSPEQVSDLLRAGESSHKVLDFNSGVPNSVLRFESNQLAANSPVEDRQGVASCVQTRGTMFGIFDGHGGHACAQAVSERLFYYMAVSLMSHKTLEQMEEAMENMKPLLPILQWLKHPGDSIYKDITSVHLDHLRVYWQELLDLHMETGLSTEEALMYSFQRLDSDISLEIQAPLEDEVTKNLSLQVAFSGATACMAHVDGVHLHIANAGDCRAILGVQGDNGAWSCLPLTCDHNAWNEAELSRLKREHPESEDRTLIIDDRLLGVLLPCRAFGDVQLKWSKELQRNVLERGFDTEALNIYQFTPPHYHTPPYLTAKPEVTYHRLRPQDKFLVLASDGLWDMLDNEDVVRLVVGHLSKVGHQKPALDQRPANLGHMQSLLLQRKASGLHAADQNAATHLIRHAIGSNEYGEMEPERLAAMLTLPEDVARMYRDDITVMVVFFNSESIDTYFKEG

Target ORF information:

RefSeq Version	XM_006255048.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus pyruvate dehyrogenase phosphatase catalytic subunit 2 (Pdp2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006255048.3

ORF Insert Sequence:

ATGTCAAGTA CTGCGTCCTA CCGGATCTTC AATTTTGCAA GGAATCGTAT TGCTGTGTTA 
CGAGGGGGTA GACGCTTGTA CTCCAGGGCA GCCACGAGTA GGAATCAAGT GAAATGGAGG 
CTCTTTTCTC CCGCATCATT GGCCGTGAAC GACAGTTCTC CACATGGTGG CTTTGCTCTG 
CGGAAAGCTT ACAGACACAC ATCAACCGAG GAAGAGGATT TCCACTTGCA GCTCAGCCCC 
GAACAGGTCA GTGACCTGCT CCGAGCTGGC GAGTCATCCC ACAAGGTTCT GGATTTCAAC 
AGCGGAGTTC CAAATTCAGT GTTAAGGTTT GAGAGCAACC AGTTGGCGGC CAATTCCCCA 
GTGGAAGACC GACAAGGTGT GGCTTCCTGC GTGCAGACGA GGGGGACGAT GTTTGGTATT 
TTTGATGGGC ATGGTGGCCA TGCGTGTGCA CAGGCGGTGA GCGAGAGGCT TTTCTATTAC 
ATGGCGGTGT CCCTCATGTC CCATAAGACC TTGGAGCAGA TGGAGGAAGC CATGGAGAAC 
ATGAAGCCTT TGCTGCCCAT CCTGCAGTGG CTCAAGCACC CCGGAGACAG TATTTATAAA 
GATATCACAT CGGTTCATCT GGACCACCTC CGAGTCTATT GGCAGGAACT CCTTGACCTA 
CATATGGAAA CGGGACTAAG CACTGAAGAG GCATTGATGT ACTCCTTCCA GAGACTGGAC 
TCCGACATCT CGCTAGAAAT TCAGGCTCCT CTGGAAGATG AGGTAACGAA GAACTTATCC 
CTCCAGGTTG CTTTTTCTGG GGCGACAGCC TGCATGGCCC ACGTCGACGG AGTTCACCTG 
CACATAGCAA ATGCTGGCGA CTGCCGAGCT ATCCTGGGTG TCCAGGGAGA CAATGGAGCG 
TGGTCATGTT TACCTCTTAC CTGTGACCAC AATGCCTGGA ATGAGGCAGA GCTGTCCCGG 
CTTAAGAGAG AACACCCCGA GTCTGAGGAC AGGACACTCA TCATAGATGA CAGGCTGCTG 
GGTGTCCTCC TACCCTGCAG GGCCTTCGGG GACGTCCAGC TAAAATGGAG TAAAGAGTTG 
CAGCGGAACG TCCTAGAGAG GGGATTTGAT ACCGAGGCCC TCAACATCTA CCAGTTTACC 
CCGCCCCACT ACCACACTCC ACCCTACCTG ACTGCTAAGC CTGAGGTCAC ATACCACAGG 
CTTAGGCCCC AAGATAAGTT CCTCGTGCTG GCCTCAGATG GCCTCTGGGA CATGCTGGAC 
AATGAGGATG TGGTAAGGCT GGTGGTGGGG CACCTGTCCA AGGTCGGTCA CCAGAAGCCA 
GCCCTGGATC AAAGACCAGC CAACCTGGGC CACATGCAGA GTCTGCTGCT GCAGAGGAAA 
GCCAGCGGAC TCCATGCAGC TGACCAGAAT GCAGCCACAC ATCTGATCAG ACATGCCATC 
GGGAGCAACG AGTATGGGGA AATGGAGCCA GAGCGTCTGG CTGCCATGTT GACGCTGCCA 
GAGGATGTGG CCAGGATGTA CCGGGATGAC ATCACTGTCA TGGTGGTGTT TTTTAACTCA 
GAATCAATTG ATACCTATTT TAAGGAGGGT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Ppm1E is an in cellulo AMP-activated protein kinase phosphatase.
Cellular signalling23(1)114-24(2011 Jan)
Voss M,Paterson J,Kelsall IR,Mart?n-Granados C,Hastie CJ,Peggie MW,Cohen PT

Pyruvate dehydrogenase kinase regulatory mechanisms and inhibition in treating diabetes, heart ischemia, and cancer.
Cellular and molecular life sciences : CMLS64(7-8)830-49(2007 Apr)
Roche TE,Hiromasa Y

Starvation and diabetes reduce the amount of pyruvate dehydrogenase phosphatase in rat heart and kidney.
Diabetes52(6)1371-6(2003 Jun)
Huang B,Wu P,Popov KM,Harris RA

Isoenzymes of pyruvate dehydrogenase phosphatase. DNA-derived amino acid sequences, expression, and regulation.
The Journal of biological chemistry273(28)17680-8(1998 Jul)
Huang B,Gudi R,Wu P,Harris RA,Hamilton J,Popov KM