Il6r cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Il6r
Entrez Gene ID	24499
Full Name	interleukin 6 receptor
Synonyms	IL6R1,Il6ra
General protein information	Preferred Names interleukin 6 receptor Names interleukin-6 receptor subunit alpha IL-6 receptor subunit alpha IL-6R 1 IL-6R subunit alpha IL-6R-alpha IL-6RA interleukin 6 receptor, alpha
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 2 Map Location: 2q34
Summary	alpha subunit of the interleukin 6 receptor complex [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_008761127.2	XP_008759349.1	interleukin-6 receptor subunit alpha isoform X1
XM_017590628.1	XP_017446117.1	interleukin-6 receptor subunit alpha isoform X4
XM_006232587.3	XP_006232649.1	interleukin-6 receptor subunit alpha isoform X2
XM_006232588.3	XP_006232650.1	interleukin-6 receptor subunit alpha isoform X3
NM_017020.3	NP_058716.2	interleukin-6 receptor subunit alpha precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	IL6R	NP_000556.1
	IL6R	XP_001114404.1
Rattus norvegicus (Norway rat)	Il6r	NP_058716.2
Canis lupus familiaris (dog)	IL6R	XP_855105.1
Danio rerio (zebrafish)	il6r	NP_001107790.1
Xenopus tropicalis (tropical clawed frog)	il6r	XP_002943407.2
Bos taurus (cattle)	IL6R	NP_001104255.1
Pan troglodytes (chimpanzee)	IL6R	XP_524889.3
Mus musculus (house mouse)	Il6ra	NP_034689.2

Gene Ontology
Bibliography

Related articles in PubMed

Aerobic exercise blocks interleukin-6 levels and germ cell apoptosis in obese rats.
Li NC, Wei XX, Hu YL, Hou X, Xu H
Andrologia(2017 Aug)

Association of genetic variations in IL-6/IL-6R pathway genes with gastric cancer risk in a Chinese population.
Zhang JZ, Liu CM, Peng HP, Zhang Y
Gene6231-4(2017 Aug)

Rs12976445 Polymorphism is Associated with Risk of Diabetic Nephropathy Through Modulating Expression of MicroRNA-125 and Interleukin-6R.
Li C, Lei T
Medical science monitor : international medical journal of experimental and clinical research213490-7(2015 Nov)

Interleukin-6 (IL-6) mediated the increased contraction of distal colon in streptozotocin-induced diabetes in rats via IL-6 receptor pathway.
Chang XW, Qin Y, Jin Z, Xi TF, Yang X, Lu ZH, Tang YP, Cai WT, Chen SJ, Xie DP
International journal of clinical and experimental pathology8(5)4514-24(2015)

Interleukin-6 receptor blockade suppresses subretinal fibrosis in a mouse model.
Cui W, Zhang H, Liu ZL
International journal of ophthalmology7(2)194-7(2014)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Diabetic rats show an increase in the contractions of distal colon partly via the IL-6-IL-6 receptor pathway.
Title: Interleukin-6 (IL-6) mediated the increased contraction of distal colon in streptozotocin-induced diabetes in rats via IL-6 receptor pathway.

antisense to IL-6 receptor subunit gp130 (gp130), but not to tumor necrosis factor receptor type 1 (TNFR1), inhibited hyperalgesia in NLB rats. However, antisense against either gp130 or TNFR1 inhibited sound stress-induced enhancement of hyperalgesia.
Title: Stress in the adult rat exacerbates muscle pain induced by early-life stress.

Paradoxically, the association of pregnancy, inflammation and anti-IL-6R increases the inflammatory effects of LPS.
Title: Effect of interleukin-6 receptor blockade on feto-maternal outcomes in a rat model of intrauterine inflammation.

CB1R and IL-6R co-stimulation enhanced the differentiation of rat cortical neuron primary cultures.
Title: Cannabinoid 1 receptor and interleukin-6 receptor together induce integration of protein kinase and transcription factor signaling to trigger neurite outgrowth.

Asymmetrical release of brain IL-6 by cerebral cortical astrocytes to the inflammatory insults both in protein and mRNA levels.
Title: Asymmetrical release of interleukin-6 by cultured cerebral cortical astrocytes treated with lipopolysaccharide.

The following Il6r gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Il6r cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa02535	NM_017020.3 Latest version!	Rattus norvegicus interleukin 6 receptor (Il6r), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa24838	XM_006232587.3 Latest version!	Rattus norvegicus interleukin 6 receptor (Il6r), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa24839	XM_006232588.3 Latest version!	Rattus norvegicus interleukin 6 receptor (Il6r), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa42913	XM_008761127.2 Latest version!	Rattus norvegicus interleukin 6 receptor (Il6r), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa59625	XM_017590628.1 Latest version!	Rattus norvegicus interleukin 6 receptor (Il6r), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Il6r ( NM_017020.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_058716.2 Rattus norvegicus interleukin 6 receptor (Il6r), mRNA.

Price & Availability↑

CloneID	ORa02535
Clone ID Related Accession (Same CDS sequence)	NM_017020.3
Accession Version	NM_017020.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1389bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Rattus norvegicus(Norway rat)
Product	interleukin-6 receptor subunit alpha precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07012144.1 and AC094121.7. On Jan 1, 2008 this sequence version replaced NM_017020.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M58587.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGCTGGCCG TCGGCTGCAC CCTGCTGGTC GCCCTGCTGG CCGCGCCCGC AGTCGCGCTG 
GTCCTTGGGA GCTGCCGCGC GCTGGAGGTG GCAAATGGTA CGGTGACGAG CCTGCCAGGG 
GCCACTGTTA CCCTGATCTG CCCTGGGAAG GAAGCAGCAG GCAATGCTAC CATTCACTGG 
GTGTACTCAG GCTCACAGAG CAGAGAATGG ACTACCACGG GAAACACACT GGTTCTGAGG 
GCCGTGCAGG TCAACGACAC TGGGCACTAT TTGTGCTTCC TGGATGATCA TCTGGTTGGG 
ACTGTGCCCT TGCTGGTGGA TGTTCCCCCA GAGGAGCCCA AGCTCTCCTG CTTCCGGAAG 
AACCCCCTTG TAAATGCCTT TTGTGAGTGG CATCCAAGCA GCACTCCCTC TCCAACCACG 
AAGGCTGTGA TGTTTGCAAA GAAAATCAAC ACCACCAATG GGAAGAGTGA CTTCCAGGTG 
CCTTGCCAGT ATTCTCAGCA GCTGAAAAGC TTCTCCTGCG AGGTGGAGAT CCTGGAGGGT 
GACAAAGTGT ACCACATAGT GTCACTGTGC GTTGCAAACA GTGTCGGAAG CAGGTCCAGC 
CACAATGTAG TATTTCAGAG TTTAAAAATG GTGCAGCCGG ATCCACCTGC CAACCTTGTG 
GTATCAGCCA TACCTGGAAG GCCTCGTTGG CTCAAAGTCA GTTGGCAAGA CCCTGAGTCC 
TGGGACCCAA GTTACTACTT GTTGCAATTC GAGCTTCGAT ACCGACCTGT ATGGTCAAAG 
ACGTTCACGG TGTGGCCGCT CCAGGTGGCC CAGCATCAAT GTGTCATCCA TGATGCCTTG 
CGAGGAGTAA AGCATGTGGT GCAGGTCCGA GGGAAGGAGG AGTTTGACAT TGGCCAGTGG 
AGCAAATGGT CCCCGGAGGT CACAGGCACT CCTTGGCTAG CAGAGCCCAG GACCACTCCG 
GCAGGGATCC CGGGGAACCC CACACAGGTC TCTGTTGAAG ACTATGACAA CCACGAGGAT 
CAGTACGGAA GTTCTACAGA AGCAACGAGT GTCCTCGCCC CAGTGCAAGG ATCCTCGCCT 
ATACCCCTGC CCACATTCCT GGTAGCTGGA GGAAGCCTGG CGTTTGGATT GCTTCTCTGT 
GTCTTCATCA TCTTGAGACT CAAGAAGAAA TGGAAGTCAC AGGCTGAGAA GGAAAGCAAG 
ACGACTTCTC CCCCACCGTA TCCCTTGGGA CCGCTGAAGC CGACCTTCCT CCTGGTTCCT 
CTCCTCACCC CATCAGGGTC CCATAACAGC TCTGGGACTG ACAACACCGG AAGCCACAGC 
TGCCTGGGTG TCAGGGACCC ACAGTGCCCT AATGACAACA GCAACAGAGA CTACTTATTC 
CCCAGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_058716.2
CDS	20..1408
Translation	MLAVGCTLLVALLAAPAVALVLGSCRALEVANGTVTSLPGATVTLICPGKEAAGNATIHWVYSGSQSREWTTTGNTLVLRAVQVNDTGHYLCFLDDHLVGTVPLLVDVPPEEPKLSCFRKNPLVNAFCEWHPSSTPSPTTKAVMFAKKINTTNGKSDFQVPCQYSQQLKSFSCEVEILEGDKVYHIVSLCVANSVGSRSSHNVVFQSLKMVQPDPPANLVVSAIPGRPRWLKVSWQDPESWDPSYYLLQFELRYRPVWSKTFTVWPLQVAQHQCVIHDALRGVKHVVQVRGKEEFDIGQWSKWSPEVTGTPWLAEPRTTPAGIPGNPTQVSVEDYDNHEDQYGSSTEATSVLAPVQGSSPIPLPTFLVAGGSLAFGLLLCVFIILRLKKKWKSQAEKESKTTSPPPYPLGPLKPTFLLVPLLTPSGSHNSSGTDNTGSHSCLGVRDPQCPNDNSNRDYLFPR

Target ORF information:

RefSeq Version	NM_017020.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus interleukin 6 receptor (Il6r), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_017020.3

ORF Insert Sequence:

ATGCTGGCCG TCGGCTGCAC CCTGCTGGTC GCCCTGCTGG CCGCGCCCGC AGTCGCGCTG 
GTCCTTGGGA GCTGCCGCGC GCTGGAGGTG GCAAATGGTA CGGTGACGAG CCTGCCAGGG 
GCCACTGTTA CCCTGATCTG CCCTGGGAAG GAAGCAGCAG GCAATGCTAC CATTCACTGG 
GTGTACTCAG GCTCACAGAG CAGAGAATGG ACTACCACGG GAAACACACT GGTTCTGAGG 
GCCGTGCAGG TCAACGACAC TGGGCACTAT TTGTGCTTCC TGGATGATCA TCTGGTTGGG 
ACTGTGCCCT TGCTGGTGGA TGTTCCCCCA GAGGAGCCCA AGCTCTCCTG CTTCCGGAAG 
AACCCCCTTG TAAATGCCTT TTGTGAGTGG CATCCAAGCA GCACTCCCTC TCCAACCACG 
AAGGCTGTGA TGTTTGCAAA GAAAATCAAC ACCACCAATG GGAAGAGTGA CTTCCAGGTG 
CCTTGCCAGT ATTCTCAGCA GCTGAAAAGC TTCTCCTGCG AGGTGGAGAT CCTGGAGGGT 
GACAAAGTGT ACCACATAGT GTCACTGTGC GTTGCAAACA GTGTCGGAAG CAGGTCCAGC 
CACAATGTAG TATTTCAGAG TTTAAAAATG GTGCAGCCGG ATCCACCTGC CAACCTTGTG 
GTATCAGCCA TACCTGGAAG GCCTCGTTGG CTCAAAGTCA GTTGGCAAGA CCCTGAGTCC 
TGGGACCCAA GTTACTACTT GTTGCAATTC GAGCTTCGAT ACCGACCTGT ATGGTCAAAG 
ACGTTCACGG TGTGGCCGCT CCAGGTGGCC CAGCATCAAT GTGTCATCCA TGATGCCTTG 
CGAGGAGTAA AGCATGTGGT GCAGGTCCGA GGGAAGGAGG AGTTTGACAT TGGCCAGTGG 
AGCAAATGGT CCCCGGAGGT CACAGGCACT CCTTGGCTAG CAGAGCCCAG GACCACTCCG 
GCAGGGATCC CGGGGAACCC CACACAGGTC TCTGTTGAAG ACTATGACAA CCACGAGGAT 
CAGTACGGAA GTTCTACAGA AGCAACGAGT GTCCTCGCCC CAGTGCAAGG ATCCTCGCCT 
ATACCCCTGC CCACATTCCT GGTAGCTGGA GGAAGCCTGG CGTTTGGATT GCTTCTCTGT 
GTCTTCATCA TCTTGAGACT CAAGAAGAAA TGGAAGTCAC AGGCTGAGAA GGAAAGCAAG 
ACGACTTCTC CCCCACCGTA TCCCTTGGGA CCGCTGAAGC CGACCTTCCT CCTGGTTCCT 
CTCCTCACCC CATCAGGGTC CCATAACAGC TCTGGGACTG ACAACACCGG AAGCCACAGC 
TGCCTGGGTG TCAGGGACCC ACAGTGCCCT AATGACAACA GCAACAGAGA CTACTTATTC 
CCCAGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Il6r ( XM_006232587.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006232649.1 Rattus norvegicus interleukin 6 receptor (Il6r), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa24838
Clone ID Related Accession (Same CDS sequence)	XM_006232587.3
Accession Version	XM_006232587.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1320bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	interleukin-6 receptor subunit alpha isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005101.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006232587.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGGCCG TCGGCTGCAC CCTGCTGGTC GCCCTGCTGG CCGCGCCCGC AGTCGCGCTG 
GTCCTTGGGA GCTGCCGCGC GCTGGAGGTG GCAAATGGTA CGGTGACGAG CCTGCCAGGG 
GCCACTGTTA CCCTGATCTG CCCTGGGAAG GAAGCAGCAG GCAATGCTAC CATTCACTGG 
GTGTACTCAG GCTCACAGAG CAGAGAATGG ACTACCACGG GAAACACACT GGTTCTGAGG 
GCCGTGCAGG TCAACGACAC TGGGCACTAT TTGTGCTTCC TGGATGATCA TCTGGTTGGG 
ACTGTGCCCT TGCTGGTGGA TGTTCCCCCA GAGGAGCCCA AGCTCTCCTG CTTCCGGAAG 
AACCCCCTTG TAAATGCCTT TTGTGAGTGG CATCCAAGCA GCACTCCCTC TCCAACCACG 
AAGGCTGTGA TGTTTGCAAA GAAAATCAAC ACCACCAATG GGAAGAGTGA CTTCCAGGTG 
CCTTGCCAGT ATTCTCAGCA GCTGAAAAGC TTCTCCTGCG AGGTGGAGAT CCTGGAGGGT 
GACAAAGTGT ACCACATAGT GTCACTGTGC GTTGCAAACA GTGTCGGAAG CAGGTCCAGC 
CACAATGTAG TATTTCAGAG TTTAAAAATG GTGCAGCCGG ATCCACCTGC CAACCTTGTG 
GTATCAGCCA TACCTGGAAG GCCTCGTTGG CTCAAAGTCA GTTGGCAAGA CCCTGAGTCC 
TGGGACCCAA GTTACTACTT GTTGCAATTC GAGCTTCGAT ACCGACCTGT ATGGTCAAAG 
ACGTTCACGG TGTGGCCGCT CCAGGTGGCC CAGCATCAAT GTGTCATCCA TGATGCCTTG 
CGAGGAGTAA AGCATGTGGT GCAGGTCCGA GGGAAGGAGG AGTTTGACAT TGGCCAGTGG 
AGCAAATGGT CCCCGGAGGT CACAGGCACT CCTTGGCTAG CAGAGCCCAG GACCACTCCG 
GCAGGGATCC CGGGGAACCC CACACAGGTC TCTGTTGAAG ACTATGACAA CCACGAGGAT 
CAGTACGGAA GTTCTACAGA AGCAACGAGT GTCCTCGCCC CAGTGCAAGG ATCCTCGCCT 
ATACCCCTGC CCACATTCCT GGTAGCTGGA GGAAGCCTGG CGTTTGGATT GCTTCTCTGT 
GTCTTCATCA TCTTGAGATG TCTGAGTCTG TCTCCCACTG AAGATGATCT TGGGCAAGAA 
AAACCTGGGA CCCAGCCTTC TCAATATTCC GAACAGAAGG AAAACCATCA TGTGGACACT 
TTGCAGGTAA GAGTAGAGGG TGGCTGCCAA GGACCAGCCT TAGCTTGGTC AGGGTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006232649.1
CDS	1455..2774
Translation	MLAVGCTLLVALLAAPAVALVLGSCRALEVANGTVTSLPGATVTLICPGKEAAGNATIHWVYSGSQSREWTTTGNTLVLRAVQVNDTGHYLCFLDDHLVGTVPLLVDVPPEEPKLSCFRKNPLVNAFCEWHPSSTPSPTTKAVMFAKKINTTNGKSDFQVPCQYSQQLKSFSCEVEILEGDKVYHIVSLCVANSVGSRSSHNVVFQSLKMVQPDPPANLVVSAIPGRPRWLKVSWQDPESWDPSYYLLQFELRYRPVWSKTFTVWPLQVAQHQCVIHDALRGVKHVVQVRGKEEFDIGQWSKWSPEVTGTPWLAEPRTTPAGIPGNPTQVSVEDYDNHEDQYGSSTEATSVLAPVQGSSPIPLPTFLVAGGSLAFGLLLCVFIILRCLSLSPTEDDLGQEKPGTQPSQYSEQKENHHVDTLQVRVEGGCQGPALAWSGF

Target ORF information:

RefSeq Version	XM_006232587.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus interleukin 6 receptor (Il6r), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006232587.3

ORF Insert Sequence:

ATGCTGGCCG TCGGCTGCAC CCTGCTGGTC GCCCTGCTGG CCGCGCCCGC AGTCGCGCTG 
GTCCTTGGGA GCTGCCGCGC GCTGGAGGTG GCAAATGGTA CGGTGACGAG CCTGCCAGGG 
GCCACTGTTA CCCTGATCTG CCCTGGGAAG GAAGCAGCAG GCAATGCTAC CATTCACTGG 
GTGTACTCAG GCTCACAGAG CAGAGAATGG ACTACCACGG GAAACACACT GGTTCTGAGG 
GCCGTGCAGG TCAACGACAC TGGGCACTAT TTGTGCTTCC TGGATGATCA TCTGGTTGGG 
ACTGTGCCCT TGCTGGTGGA TGTTCCCCCA GAGGAGCCCA AGCTCTCCTG CTTCCGGAAG 
AACCCCCTTG TAAATGCCTT TTGTGAGTGG CATCCAAGCA GCACTCCCTC TCCAACCACG 
AAGGCTGTGA TGTTTGCAAA GAAAATCAAC ACCACCAATG GGAAGAGTGA CTTCCAGGTG 
CCTTGCCAGT ATTCTCAGCA GCTGAAAAGC TTCTCCTGCG AGGTGGAGAT CCTGGAGGGT 
GACAAAGTGT ACCACATAGT GTCACTGTGC GTTGCAAACA GTGTCGGAAG CAGGTCCAGC 
CACAATGTAG TATTTCAGAG TTTAAAAATG GTGCAGCCGG ATCCACCTGC CAACCTTGTG 
GTATCAGCCA TACCTGGAAG GCCTCGTTGG CTCAAAGTCA GTTGGCAAGA CCCTGAGTCC 
TGGGACCCAA GTTACTACTT GTTGCAATTC GAGCTTCGAT ACCGACCTGT ATGGTCAAAG 
ACGTTCACGG TGTGGCCGCT CCAGGTGGCC CAGCATCAAT GTGTCATCCA TGATGCCTTG 
CGAGGAGTAA AGCATGTGGT GCAGGTCCGA GGGAAGGAGG AGTTTGACAT TGGCCAGTGG 
AGCAAATGGT CCCCGGAGGT CACAGGCACT CCTTGGCTAG CAGAGCCCAG GACCACTCCG 
GCAGGGATCC CGGGGAACCC CACACAGGTC TCTGTTGAAG ACTATGACAA CCACGAGGAT 
CAGTACGGAA GTTCTACAGA AGCAACGAGT GTCCTCGCCC CAGTGCAAGG ATCCTCGCCT 
ATACCCCTGC CCACATTCCT GGTAGCTGGA GGAAGCCTGG CGTTTGGATT GCTTCTCTGT 
GTCTTCATCA TCTTGAGATG TCTGAGTCTG TCTCCCACTG AAGATGATCT TGGGCAAGAA 
AAACCTGGGA CCCAGCCTTC TCAATATTCC GAACAGAAGG AAAACCATCA TGTGGACACT 
TTGCAGGTAA GAGTAGAGGG TGGCTGCCAA GGACCAGCCT TAGCTTGGTC AGGGTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Il6r ( XM_006232588.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006232650.1 Rattus norvegicus interleukin 6 receptor (Il6r), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa24839
Clone ID Related Accession (Same CDS sequence)	XM_006232588.3
Accession Version	XM_006232588.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1296bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	interleukin-6 receptor subunit alpha isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005101.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006232588.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGGCCG TCGGCTGCAC CCTGCTGGTC GCCCTGCTGG CCGCGCCCGC AGTCGCGCTG 
GTCCTTGGGA GCTGCCGCGC GCTGGAGGTG GCAAATGGTA CGGTGACGAG CCTGCCAGGG 
GCCACTGTTA CCCTGATCTG CCCTGGGAAG GAAGCAGCAG GCAATGCTAC CATTCACTGG 
GTGTACTCAG GCTCACAGAG CAGAGAATGG ACTACCACGG GAAACACACT GGTTCTGAGG 
GCCGTGCAGG TCAACGACAC TGGGCACTAT TTGTGCTTCC TGGATGATCA TCTGGTTGGG 
ACTGTGCCCT TGCTGGTGGA TGTTCCCCCA GAGGAGCCCA AGCTCTCCTG CTTCCGGAAG 
AACCCCCTTG TAAATGCCTT TTGTGAGTGG CATCCAAGCA GCACTCCCTC TCCAACCACG 
AAGGCTGTGA TGTTTGCAAA GAAAATCAAC ACCACCAATG GGAAGAGTGA CTTCCAGGTG 
CCTTGCCAGT ATTCTCAGCA GCTGAAAAGC TTCTCCTGCG AGGTGGAGAT CCTGGAGGGT 
GACAAAGTGT ACCACATAGT GTCACTGTGC GTTGCAAACA GTGTCGGAAG CAGGTCCAGC 
CACAATGTAG TATTTCAGAG TTTAAAAATG GTGCAGCCGG ATCCACCTGC CAACCTTGTG 
GTATCAGCCA TACCTGGAAG GCCTCGTTGG CTCAAAGTCA GTTGGCAAGA CCCTGAGTCC 
TGGGACCCAA GTTACTACTT GTTGCAATTC GAGCTTCGAT ACCGACCTGT ATGGTCAAAG 
ACGTTCACGG TGTGGCCGCT CCAGGTGGCC CAGCATCAAT GTGTCATCCA TGATGCCTTG 
CGAGGAGTAA AGCATGTGGT GCAGGTCCGA GGGAAGGAGG AGTTTGACAT TGGCCAGTGG 
AGCAAATGGT CCCCGGAGGT CACAGGCACT CCTTGGCTAG CAGAGCCCAG GACCACTCCG 
GCAGGGATCC CGGGGAACCC CACACAGGTC TCTGTTGAAG ACTATGACAA CCACGAGGAT 
CAGTACGGAA GTTCTACAGA AGCAACGAGT GTCCTCGCCC CAGTGCAAGG ATCCTCGCCT 
ATACCCCTGC CCACATTCCT GGTAGCTGGA GGAAGCCTGG CGTTTGGATT GCTTCTCTGT 
GTCTTCATCA TCTTGAGATG TCTGAGTCTG TCTCCCACTG AAGATGATCT TGGGCAAGAA 
AAACCTGGGA CCCAGCCTTC TCAATATTCC GAACAGAAGG AAAACCATCA TGTGGACACT 
TTGCAGATGG GGCAGAAGGA ACAGTGCTGC ATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006232650.1
CDS	1454..2749
Translation	MLAVGCTLLVALLAAPAVALVLGSCRALEVANGTVTSLPGATVTLICPGKEAAGNATIHWVYSGSQSREWTTTGNTLVLRAVQVNDTGHYLCFLDDHLVGTVPLLVDVPPEEPKLSCFRKNPLVNAFCEWHPSSTPSPTTKAVMFAKKINTTNGKSDFQVPCQYSQQLKSFSCEVEILEGDKVYHIVSLCVANSVGSRSSHNVVFQSLKMVQPDPPANLVVSAIPGRPRWLKVSWQDPESWDPSYYLLQFELRYRPVWSKTFTVWPLQVAQHQCVIHDALRGVKHVVQVRGKEEFDIGQWSKWSPEVTGTPWLAEPRTTPAGIPGNPTQVSVEDYDNHEDQYGSSTEATSVLAPVQGSSPIPLPTFLVAGGSLAFGLLLCVFIILRCLSLSPTEDDLGQEKPGTQPSQYSEQKENHHVDTLQMGQKEQCCM

Target ORF information:

RefSeq Version	XM_006232588.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus interleukin 6 receptor (Il6r), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006232588.3

ORF Insert Sequence:

ATGCTGGCCG TCGGCTGCAC CCTGCTGGTC GCCCTGCTGG CCGCGCCCGC AGTCGCGCTG 
GTCCTTGGGA GCTGCCGCGC GCTGGAGGTG GCAAATGGTA CGGTGACGAG CCTGCCAGGG 
GCCACTGTTA CCCTGATCTG CCCTGGGAAG GAAGCAGCAG GCAATGCTAC CATTCACTGG 
GTGTACTCAG GCTCACAGAG CAGAGAATGG ACTACCACGG GAAACACACT GGTTCTGAGG 
GCCGTGCAGG TCAACGACAC TGGGCACTAT TTGTGCTTCC TGGATGATCA TCTGGTTGGG 
ACTGTGCCCT TGCTGGTGGA TGTTCCCCCA GAGGAGCCCA AGCTCTCCTG CTTCCGGAAG 
AACCCCCTTG TAAATGCCTT TTGTGAGTGG CATCCAAGCA GCACTCCCTC TCCAACCACG 
AAGGCTGTGA TGTTTGCAAA GAAAATCAAC ACCACCAATG GGAAGAGTGA CTTCCAGGTG 
CCTTGCCAGT ATTCTCAGCA GCTGAAAAGC TTCTCCTGCG AGGTGGAGAT CCTGGAGGGT 
GACAAAGTGT ACCACATAGT GTCACTGTGC GTTGCAAACA GTGTCGGAAG CAGGTCCAGC 
CACAATGTAG TATTTCAGAG TTTAAAAATG GTGCAGCCGG ATCCACCTGC CAACCTTGTG 
GTATCAGCCA TACCTGGAAG GCCTCGTTGG CTCAAAGTCA GTTGGCAAGA CCCTGAGTCC 
TGGGACCCAA GTTACTACTT GTTGCAATTC GAGCTTCGAT ACCGACCTGT ATGGTCAAAG 
ACGTTCACGG TGTGGCCGCT CCAGGTGGCC CAGCATCAAT GTGTCATCCA TGATGCCTTG 
CGAGGAGTAA AGCATGTGGT GCAGGTCCGA GGGAAGGAGG AGTTTGACAT TGGCCAGTGG 
AGCAAATGGT CCCCGGAGGT CACAGGCACT CCTTGGCTAG CAGAGCCCAG GACCACTCCG 
GCAGGGATCC CGGGGAACCC CACACAGGTC TCTGTTGAAG ACTATGACAA CCACGAGGAT 
CAGTACGGAA GTTCTACAGA AGCAACGAGT GTCCTCGCCC CAGTGCAAGG ATCCTCGCCT 
ATACCCCTGC CCACATTCCT GGTAGCTGGA GGAAGCCTGG CGTTTGGATT GCTTCTCTGT 
GTCTTCATCA TCTTGAGATG TCTGAGTCTG TCTCCCACTG AAGATGATCT TGGGCAAGAA 
AAACCTGGGA CCCAGCCTTC TCAATATTCC GAACAGAAGG AAAACCATCA TGTGGACACT 
TTGCAGATGG GGCAGAAGGA ACAGTGCTGC ATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Il6r ( XM_008761127.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008759349.1 Rattus norvegicus interleukin 6 receptor (Il6r), transcript variant X1, mRNA.

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CloneID	ORa42913
Clone ID Related Accession (Same CDS sequence)	XM_008761127.2
Accession Version	XM_008761127.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1386bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	interleukin-6 receptor subunit alpha isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005101.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008761127.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGGCCG TCGGCTGCAC CCTGCTGGTC GCCCTGCTGG CCGCGCCCGC AGTCGCGCTG 
GTCCTTGGGA GCTGCCGCGC GCTGGAGGTG GCAAATGGTA CGGTGACGAG CCTGCCAGGG 
GCCACTGTTA CCCTGATCTG CCCTGGGAAG GAAGCAGCAG GCAATGCTAC CATTCACTGG 
GTGTACTCAG GCTCACAGAG CAGAGAATGG ACTACCACGG GAAACACACT GGTTCTGAGG 
GCCGTGCAGG TCAACGACAC TGGGCACTAT TTGTGCTTCC TGGATGATCA TCTGGTTGGG 
ACTGTGCCCT TGCTGGTGGA TGTTCCCCCA GAGGAGCCCA AGCTCTCCTG CTTCCGGAAG 
AACCCCCTTG TAAATGCCTT TTGTGAGTGG CATCCAAGCA GCACTCCCTC TCCAACCACG 
AAGGCTGTGA TGTTTGCAAA GAAAATCAAC ACCACCAATG GGAAGAGTGA CTTCCAGGTG 
CCTTGCCAGT ATTCTCAGCA GCTGAAAAGC TTCTCCTGCG AGGTGGAGAT CCTGGAGGGT 
GACAAAGTGT ACCACATAGT GTCACTGTGC GTTGCAAACA GTGTCGGAAG CAGGTCCAGC 
CACAATGTAG TATTTCAGAG TTTAAAAATG GTGCAGCCGG ATCCACCTGC CAACCTTGTG 
GTATCAGCCA TACCTGGAAG GCCTCGTTGG CTCAAAGTCA GTTGGCAAGA CCCTGAGTCC 
TGGGACCCAA GTTACTACTT GTTGCAATTC GAGCTTCGAT ACCGACCTGT ATGGTCAAAG 
ACGTTCACGG TGTGGCCGCT CCAGGTGGCC CAGCATCAAT GTGTCATCCA TGATGCCTTG 
CGAGGAGTAA AGCATGTGGT GCAGGTCCGA GGGAAGGAGG AGTTTGACAT TGGCCAGTGG 
AGCAAATGGT CCCCGGAGGT CACAGGCACT CCTTGGCTAG AGCCCAGGAC CACTCCGGCA 
GGGATCCCGG GGAACCCCAC ACAGGTCTCT GTTGAAGACT ATGACAACCA CGAGGATCAG 
TACGGAAGTT CTACAGAAGC AACGAGTGTC CTCGCCCCAG TGCAAGGATC CTCGCCTATA 
CCCCTGCCCA CATTCCTGGT AGCTGGAGGA AGCCTGGCGT TTGGATTGCT TCTCTGTGTC 
TTCATCATCT TGAGACTCAA GAAGAAATGG AAGTCACAGG CTGAGAAGGA AAGCAAGACG 
ACTTCTCCCC CACCGTATCC CTTGGGACCG CTGAAGCCGA CCTTCCTCCT GGTTCCTCTC 
CTCACCCCAT CAGGGTCCCA TAACAGCTCT GGGACTGACA ACACCGGAAG CCACAGCTGC 
CTGGGTGTCA GGGACCCACA GTGCCCTAAT GACAACAGCA ACAGAGACTA CTTATTCCCC 
AGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008759349.1
CDS	1448..2833
Translation	MLAVGCTLLVALLAAPAVALVLGSCRALEVANGTVTSLPGATVTLICPGKEAAGNATIHWVYSGSQSREWTTTGNTLVLRAVQVNDTGHYLCFLDDHLVGTVPLLVDVPPEEPKLSCFRKNPLVNAFCEWHPSSTPSPTTKAVMFAKKINTTNGKSDFQVPCQYSQQLKSFSCEVEILEGDKVYHIVSLCVANSVGSRSSHNVVFQSLKMVQPDPPANLVVSAIPGRPRWLKVSWQDPESWDPSYYLLQFELRYRPVWSKTFTVWPLQVAQHQCVIHDALRGVKHVVQVRGKEEFDIGQWSKWSPEVTGTPWLEPRTTPAGIPGNPTQVSVEDYDNHEDQYGSSTEATSVLAPVQGSSPIPLPTFLVAGGSLAFGLLLCVFIILRLKKKWKSQAEKESKTTSPPPYPLGPLKPTFLLVPLLTPSGSHNSSGTDNTGSHSCLGVRDPQCPNDNSNRDYLFPR

Target ORF information:

RefSeq Version	XM_008761127.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus interleukin 6 receptor (Il6r), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008761127.2

ORF Insert Sequence:

ATGCTGGCCG TCGGCTGCAC CCTGCTGGTC GCCCTGCTGG CCGCGCCCGC AGTCGCGCTG 
GTCCTTGGGA GCTGCCGCGC GCTGGAGGTG GCAAATGGTA CGGTGACGAG CCTGCCAGGG 
GCCACTGTTA CCCTGATCTG CCCTGGGAAG GAAGCAGCAG GCAATGCTAC CATTCACTGG 
GTGTACTCAG GCTCACAGAG CAGAGAATGG ACTACCACGG GAAACACACT GGTTCTGAGG 
GCCGTGCAGG TCAACGACAC TGGGCACTAT TTGTGCTTCC TGGATGATCA TCTGGTTGGG 
ACTGTGCCCT TGCTGGTGGA TGTTCCCCCA GAGGAGCCCA AGCTCTCCTG CTTCCGGAAG 
AACCCCCTTG TAAATGCCTT TTGTGAGTGG CATCCAAGCA GCACTCCCTC TCCAACCACG 
AAGGCTGTGA TGTTTGCAAA GAAAATCAAC ACCACCAATG GGAAGAGTGA CTTCCAGGTG 
CCTTGCCAGT ATTCTCAGCA GCTGAAAAGC TTCTCCTGCG AGGTGGAGAT CCTGGAGGGT 
GACAAAGTGT ACCACATAGT GTCACTGTGC GTTGCAAACA GTGTCGGAAG CAGGTCCAGC 
CACAATGTAG TATTTCAGAG TTTAAAAATG GTGCAGCCGG ATCCACCTGC CAACCTTGTG 
GTATCAGCCA TACCTGGAAG GCCTCGTTGG CTCAAAGTCA GTTGGCAAGA CCCTGAGTCC 
TGGGACCCAA GTTACTACTT GTTGCAATTC GAGCTTCGAT ACCGACCTGT ATGGTCAAAG 
ACGTTCACGG TGTGGCCGCT CCAGGTGGCC CAGCATCAAT GTGTCATCCA TGATGCCTTG 
CGAGGAGTAA AGCATGTGGT GCAGGTCCGA GGGAAGGAGG AGTTTGACAT TGGCCAGTGG 
AGCAAATGGT CCCCGGAGGT CACAGGCACT CCTTGGCTAG AGCCCAGGAC CACTCCGGCA 
GGGATCCCGG GGAACCCCAC ACAGGTCTCT GTTGAAGACT ATGACAACCA CGAGGATCAG 
TACGGAAGTT CTACAGAAGC AACGAGTGTC CTCGCCCCAG TGCAAGGATC CTCGCCTATA 
CCCCTGCCCA CATTCCTGGT AGCTGGAGGA AGCCTGGCGT TTGGATTGCT TCTCTGTGTC 
TTCATCATCT TGAGACTCAA GAAGAAATGG AAGTCACAGG CTGAGAAGGA AAGCAAGACG 
ACTTCTCCCC CACCGTATCC CTTGGGACCG CTGAAGCCGA CCTTCCTCCT GGTTCCTCTC 
CTCACCCCAT CAGGGTCCCA TAACAGCTCT GGGACTGACA ACACCGGAAG CCACAGCTGC 
CTGGGTGTCA GGGACCCACA GTGCCCTAAT GACAACAGCA ACAGAGACTA CTTATTCCCC 
AGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Il6r ( XM_017590628.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017446117.1 Rattus norvegicus interleukin 6 receptor (Il6r), transcript variant X4, mRNA.

Price & Availability↑

CloneID	ORa59625
Clone ID Related Accession (Same CDS sequence)	XM_017590628.1
Accession Version	XM_017590628.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1209bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	interleukin-6 receptor subunit alpha isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005101.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGGCCG TCGGCTGCAC CCTGCTGGTC GCCCTGCTGG CCGCGCCCGC AGTCGCGCTG 
GTCCTTGGGA GCTGCCGCGC GCTGGAGGTG GCAAATGGTA CGGTGACGAG CCTGCCAGGG 
GCCACTGTTA CCCTGATCTG CCCTGGGAAG GAAGCAGCAG GCAATGCTAC CATTCACTGG 
GTGTACTCAG GCTCACAGAG CAGAGAATGG ACTACCACGG GAAACACACT GGTTCTGAGG 
GCCGTGCAGG TCAACGACAC TGGGCACTAT TTGTGCTTCC TGGATGATCA TCTGGTTGGG 
ACTGTGCCCT TGCTGGTGGA TGTTCCCCCA GAGGAGCCCA AGCTCTCCTG CTTCCGGAAG 
AACCCCCTTG TAAATGCCTT TTGTGAGTGG CATCCAAGCA GCACTCCCTC TCCAACCACG 
AAGGCTGTGA TGTTTGCAAA GAAAATCAAC ACCACCAATG GGAAGAGTGA CTTCCAGGTG 
CCTTGCCAGT ATTCTCAGCA GCTGAAAAGC TTCTCCTGCG AGGTGGAGAT CCTGGAGGGT 
GACAAAGTGT ACCACATAGT GTCACTGTGC GTTGCAAACA GTGTCGGAAG CAGGTCCAGC 
CACAATGTAG TATTTCAGAG TTTAAAAATG GTGCAGCCGG ATCCACCTGC CAACCTTGTG 
GTATCAGCCA TACCTGGAAG GCCTCGTTGG CTCAAAGTCA GTTGGCAAGA CCCTGAGTCC 
TGGGACCCAA GTTACTACTT GTTGCAATTC GAGCTTCGAT ACCGACCTGT ATGGTCAAAG 
ACGTTCACGG TGTGGCCGCT CCAGGTGGCC CAGCATCAAT GTGTCATCCA TGATGCCTTG 
CGAGGAGTAA AGCATGTGGT GCAGGTCCGA GGGAAGGAGG AGTTTGACAT TGGCCAGTGG 
AGCAAATGGT CCCCGGAGGT CACAGGCACT CCTTGGCTAG CAGAGCCCAG GACCACTCCG 
GCAGGGATCC CGGGGAACCC CACACAGGTC TCTGTTGAAG ACTATGACAA CCACGAGGAT 
CAGTACGGAA GTTCTACAGA AGCAACGAGT GTCCTCGCCC CAGTGCAAGG ATCCTCGCCT 
ATACCCCTGC CCACATTCCT GGTAGCTGGA GGAAGCCTGG CGTTTGGATT GCTTCTCTGT 
GTCTTCATCA TCTTGAGTCT GGAATCCGCA GGAACACAGA GTTTAAGGCC AGCAGGAGCT 
ACAGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017446117.1
CDS	1451..2659
Translation	MLAVGCTLLVALLAAPAVALVLGSCRALEVANGTVTSLPGATVTLICPGKEAAGNATIHWVYSGSQSREWTTTGNTLVLRAVQVNDTGHYLCFLDDHLVGTVPLLVDVPPEEPKLSCFRKNPLVNAFCEWHPSSTPSPTTKAVMFAKKINTTNGKSDFQVPCQYSQQLKSFSCEVEILEGDKVYHIVSLCVANSVGSRSSHNVVFQSLKMVQPDPPANLVVSAIPGRPRWLKVSWQDPESWDPSYYLLQFELRYRPVWSKTFTVWPLQVAQHQCVIHDALRGVKHVVQVRGKEEFDIGQWSKWSPEVTGTPWLAEPRTTPAGIPGNPTQVSVEDYDNHEDQYGSSTEATSVLAPVQGSSPIPLPTFLVAGGSLAFGLLLCVFIILSLESAGTQSLRPAGATE

Target ORF information:

RefSeq Version	XM_017590628.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus interleukin 6 receptor (Il6r), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017590628.1

ORF Insert Sequence:

ATGCTGGCCG TCGGCTGCAC CCTGCTGGTC GCCCTGCTGG CCGCGCCCGC AGTCGCGCTG 
GTCCTTGGGA GCTGCCGCGC GCTGGAGGTG GCAAATGGTA CGGTGACGAG CCTGCCAGGG 
GCCACTGTTA CCCTGATCTG CCCTGGGAAG GAAGCAGCAG GCAATGCTAC CATTCACTGG 
GTGTACTCAG GCTCACAGAG CAGAGAATGG ACTACCACGG GAAACACACT GGTTCTGAGG 
GCCGTGCAGG TCAACGACAC TGGGCACTAT TTGTGCTTCC TGGATGATCA TCTGGTTGGG 
ACTGTGCCCT TGCTGGTGGA TGTTCCCCCA GAGGAGCCCA AGCTCTCCTG CTTCCGGAAG 
AACCCCCTTG TAAATGCCTT TTGTGAGTGG CATCCAAGCA GCACTCCCTC TCCAACCACG 
AAGGCTGTGA TGTTTGCAAA GAAAATCAAC ACCACCAATG GGAAGAGTGA CTTCCAGGTG 
CCTTGCCAGT ATTCTCAGCA GCTGAAAAGC TTCTCCTGCG AGGTGGAGAT CCTGGAGGGT 
GACAAAGTGT ACCACATAGT GTCACTGTGC GTTGCAAACA GTGTCGGAAG CAGGTCCAGC 
CACAATGTAG TATTTCAGAG TTTAAAAATG GTGCAGCCGG ATCCACCTGC CAACCTTGTG 
GTATCAGCCA TACCTGGAAG GCCTCGTTGG CTCAAAGTCA GTTGGCAAGA CCCTGAGTCC 
TGGGACCCAA GTTACTACTT GTTGCAATTC GAGCTTCGAT ACCGACCTGT ATGGTCAAAG 
ACGTTCACGG TGTGGCCGCT CCAGGTGGCC CAGCATCAAT GTGTCATCCA TGATGCCTTG 
CGAGGAGTAA AGCATGTGGT GCAGGTCCGA GGGAAGGAGG AGTTTGACAT TGGCCAGTGG 
AGCAAATGGT CCCCGGAGGT CACAGGCACT CCTTGGCTAG CAGAGCCCAG GACCACTCCG 
GCAGGGATCC CGGGGAACCC CACACAGGTC TCTGTTGAAG ACTATGACAA CCACGAGGAT 
CAGTACGGAA GTTCTACAGA AGCAACGAGT GTCCTCGCCC CAGTGCAAGG ATCCTCGCCT 
ATACCCCTGC CCACATTCCT GGTAGCTGGA GGAAGCCTGG CGTTTGGATT GCTTCTCTGT 
GTCTTCATCA TCTTGAGTCT GGAATCCGCA GGAACACAGA GTTTAAGGCC AGCAGGAGCT 
ACAGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Aerobic exercise blocks interleukin-6 levels and germ cell apoptosis in obese rats.
Andrologia(2017 Aug)
Li NC,Wei XX,Hu YL,Hou X,Xu H

Association of genetic variations in IL-6/IL-6R pathway genes with gastric cancer risk in a Chinese population.
Gene6231-4(2017 Aug)
Zhang JZ,Liu CM,Peng HP,Zhang Y

Rs12976445 Polymorphism is Associated with Risk of Diabetic Nephropathy Through Modulating Expression of MicroRNA-125 and Interleukin-6R.
Medical science monitor : international medical journal of experimental and clinical research213490-7(2015 Nov)
Li C,Lei T

Interleukin-6 (IL-6) mediated the increased contraction of distal colon in streptozotocin-induced diabetes in rats via IL-6 receptor pathway.
International journal of clinical and experimental pathology8(5)4514-24(2015)
Chang XW,Qin Y,Jin Z,Xi TF,Yang X,Lu ZH,Tang YP,Cai WT,Chen SJ,Xie DP

Interleukin-6 receptor blockade suppresses subretinal fibrosis in a mouse model.
International journal of ophthalmology7(2)194-7(2014)
Cui W,Zhang H,Liu ZL

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Il6r cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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