The following Hoxb8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Hoxb8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa07334 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001191649.1 | |
| Accession Version | NM_001191649.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 732bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-27 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | homeobox protein Hox-B8 | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AABR07030395.1. On Jul 17, 2010 this sequence version replaced XM_220888.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA2689597, SAMN02642595 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGAGCTCTT ATTTCGTCAA CTCACTGTTC TCCAAATACA AAACCGGGGA GTCCCTGCGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001178578.1 |
| CDS | 1..732 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001191649.1 |
1 | ATGAGCTCTT ATTTCGTCAA CTCACTGTTC TCCAAATACA AAACCGGGGA GTCCCTGCGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa33609 | |
| Clone ID Related Accession (Same CDS sequence) | XM_006247175.3 | |
| Accession Version | XM_006247175.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 729bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-07-25 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | homeobox protein Hox-B8 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006247175.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGAGCTCTT ATTTCGTCAA CTCACTGTTC TCCAAATACA AAACCGGGGA GTCCCTGCGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_006247237.1 |
| CDS | 12..740 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_006247175.3 |
1 | ATGAGCTCTT ATTTCGTCAA CTCACTGTTC TCCAAATACA AAACCGGGGA GTCCCTGCGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Loss of Hoxb8 alters spinal dorsal laminae and sensory responses in mice. |
Regulation of smooth muscle-specific gene expression by homeodomain proteins, Hoxa10 and Hoxb8. |
In vivo mutagenesis of the Hoxb8 hexapeptide domain leads to dominant homeotic transformations that mimic the loss-of-function mutations in genes of the Hoxb cluster. |
Hoxb8 is required for normal grooming behavior in mice. |
HoxB8 requires its Pbx-interaction motif to block differentiation of primary myeloid progenitors and of most cell line models of myeloid differentiation. |
