gRNAs
The following Cdk12 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cdk12 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa02020 | |
| Clone ID Related Accession (Same CDS sequence) | NM_138916.2 | |
| Accession Version | NM_138916.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 3777bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-02-16 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | cyclin-dependent kinase 12 isoform 2 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AY072294.1 and BE117540.1. On Sep 29, 2005 this sequence version replaced NM_138916.1. ##Evidence-Data-START## Transcript exon combination :: AY072294.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGCCCAATT CAGAGAGACA TGGGGGCAAG AAGGACGGGA GTGGAGGAGC TTCTGGAACT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_620271.1 |
| CDS | 66..3842 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_138916.2 |
1 | ATGCCCAATT CAGAGAGACA TGGGGGCAAG AAGGACGGGA GTGGAGGAGC TTCTGGAACT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa39831 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001033867.1 | |
| Accession Version | NM_001033867.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 4455bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2012-03-24 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | cyclin-dependent kinase 12 isoform 1 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AY962568.1 and AABR03073305.1. Sequence Note: This RefSeq record was created using sequences from two different strains, Sprague-Dawley and BN/SsNHsdMCW, because no single transcript from the same strain was available for the full length of the gene. | |
1 | ATGCCCAATT CAGAGAGACA TGGGGGCAAG AAGGACGGGA GTGGAGGAGC TTCTGGAACT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001029039.1 |
| CDS | 66..4520 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001033867.1 |
1 | ATGCCCAATT CAGAGAGACA TGGGGGCAAG AAGGACGGGA GTGGAGGAGC TTCTGGAACT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa33641 | |
| Clone ID Related Accession (Same CDS sequence) | XM_006247250.3 | |
| Accession Version | XM_006247250.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 4452bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-07-25 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | cyclin-dependent kinase 12 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006247250.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGCCCAATT CAGAGAGACA TGGGGGCAAG AAGGACGGGA GTGGAGGAGC TTCTGGAACT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_006247312.1 |
| CDS | 622..5073 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_006247250.3 |
1 | ATGCCCAATT CAGAGAGACA TGGGGGCAAG AAGGACGGGA GTGGAGGAGC TTCTGGAACT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa33642 | |
| Clone ID Related Accession (Same CDS sequence) | XM_006247251.3 | |
| Accession Version | XM_006247251.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 4428bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-07-25 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | cyclin-dependent kinase 12 isoform X2 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006247251.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGCCCAATT CAGAGAGACA TGGGGGCAAG AAGGACGGGA GTGGAGGAGC TTCTGGAACT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_006247313.1 |
| CDS | 621..5048 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_006247251.3 |
1 | ATGCCCAATT CAGAGAGACA TGGGGGCAAG AAGGACGGGA GTGGAGGAGC TTCTGGAACT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The writers, readers, and functions of the RNA polymerase II C-terminal domain code. |
Updating the RNA polymerase CTD code: adding gene-specific layers. |
Cyclin K-containing kinase complexes maintain self-renewal in murine embryonic stem cells. |
The Cyclin K/Cdk12 complex maintains genomic stability via regulation of expression of DNA damage response genes. |
CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1. |
