Snrpb cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Snrpb
Entrez Gene ID	171365
Full Name	small nuclear ribonucleoprotein polypeptides B and B1
General protein information	Preferred Names small nuclear ribonucleoprotein polypeptides B and B1 Names small nuclear ribonucleoprotein-associated protein B SM11 sm protein B sm-B smB snRNP-B
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 3 Map Location: 3q36
Summary	one of several nuclear proteins that are small ribonucleoprotein particles (snRNPs); may play a role in pre-mRNA splicing [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_134358.1	NP_599185.1	small nuclear ribonucleoprotein-associated protein B

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	SNRPB	XP_861671.1
Homo sapiens (human)	SNRPB	NP_937859.1
Bos taurus (cattle)	SNRPB	NP_001029903.1
Mus musculus (house mouse)	Snrpb	NP_033251.1
Pan troglodytes (chimpanzee)	SNRPB	XP_525398.2
	SNRPB	XP_001113951.1
Rattus norvegicus (Norway rat)	Snrpb	NP_599185.1

Gene Ontology
Bibliography

Related articles in PubMed

Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation.
Bertram K, Agafonov DE, Dybkov O, Haselbach D, Leelaram MN, Will CL, Urlaub H, Kastner B, L?hrmann R, Stark H
Cell170(4)701-713.e11(2017 Aug)

Cryo-EM structure of a human spliceosome activated for step 2 of splicing.
Bertram K, Agafonov DE, Liu WT, Dybkov O, Will CL, Hartmuth K, Urlaub H, Kastner B, Stark H, L?hrmann R
Nature542(7641)318-323(2017 02)

Molecular architecture of the human U4/U6.U5 tri-snRNP.
Agafonov DE, Kastner B, Dybkov O, Hofele RV, Liu WT, Urlaub H, L?hrmann R, Stark H
Science (New York, N.Y.)351(6280)1416-20(2016 Mar)

Crystal structure of human U1 snRNP, a small nuclear ribonucleoprotein particle, reveals the mechanism of 5' splice site recognition.
Kondo Y, Oubridge C, van Roon AM, Nagai K
eLife4(2015 Jan)

Identification of novel deregulated RNA metabolism-related genes in non-small cell lung cancer.
Valles I, Pajares MJ, Segura V, Guruceaga E, Gomez-Roman J, Blanco D, Tamura A, Montuenga LM, Pio R
PloS one7(8)e42086(2012)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Snrpb gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Snrpb cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa01180	NM_134358.1 Latest version!	Rattus norvegicus small nuclear ribonucleoprotein polypeptides B and B1 (Snrpb), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Snrpb ( NM_134358.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_599185.1 Rattus norvegicus small nuclear ribonucleoprotein polypeptides B and B1 (Snrpb), mRNA.

Price & Availability↑

CloneID	ORa01180
Clone ID Related Accession (Same CDS sequence)	NM_134358.1
Accession Version	NM_134358.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 696bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-03
Organism	Rattus norvegicus(Norway rat)
Product	small nuclear ribonucleoprotein-associated protein B
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC158686.1. On or before Jun 5, 2008 this sequence version replaced XM_001059527.1, XM_001079072.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC158686.1, FQ220740.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01906348, SAMN01906349 [ECO:0000348] ##Evidence-Data-END##

ATGACGGTGG GCAAGAGCAG CAAGATGCTG CAGCACATCG ACTACAGGAT GAGGTGCATC 
CTGCAAGATG GCCGGATCTT CATCGGGACC TTCAAAGCTT TTGACAAGCA TATGAACTTG 
ATCCTCTGTG ACTGTGATGA GTTCAGGAAG ATCAAGCCAA AGAACTCCAA ACAAGCAGAA 
AGAGAAGAGA AGCGAGTCCT TGGTCTGGTG TTGCTTCGAG GAGAGAACCT GGTCTCCATG 
ACAGTAGAAG GACCTCCTCC CAAAGATACT GGCATTGCCC GAGTGCCACT TGCTGGAGCT 
GCTGGGGGGC CAGGCATCGG CAGGGCTGCT GGCAGAGGAA TCCCGGCGGG TGTGCCCATG 
CCCCAGGCTC CTGCAGGGCT TGCTGGACCA GTGCGAGGTG TTGGAGGGCC GTCCCAGCAG 
GTGATGACCC CACAAGGAAG AGGCACTGTG GCAGCTGCTG CAGCTGCAGC CACAGCCAGT 
ATTGCAGGAG CCCCAACTCA GTACCCACCT GGTCGTGGGG GTCCTCCTCC ACCTATGGGC 
CGAGGGGCAC CTCCTCCAGG TATGATGGGC CCACCTCCTG GCATGAGGCC TCCCATGGGT 
CCCCCAATGG GGATCCCTCC TGGCCGAGGA ACTCCAATGG GCATGCCCCC TCCTGGGATG 
CGACCTCCTC CTCCAGGCAT GCGAGGTCTG CTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_599185.1
CDS	97..792
Translation	MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQAEREEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGPPPGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRGLL

Target ORF information:

RefSeq Version	NM_134358.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus small nuclear ribonucleoprotein polypeptides B and B1 (Snrpb), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_134358.1

ORF Insert Sequence:

ATGACGGTGG GCAAGAGCAG CAAGATGCTG CAGCACATCG ACTACAGGAT GAGGTGCATC 
CTGCAAGATG GCCGGATCTT CATCGGGACC TTCAAAGCTT TTGACAAGCA TATGAACTTG 
ATCCTCTGTG ACTGTGATGA GTTCAGGAAG ATCAAGCCAA AGAACTCCAA ACAAGCAGAA 
AGAGAAGAGA AGCGAGTCCT TGGTCTGGTG TTGCTTCGAG GAGAGAACCT GGTCTCCATG 
ACAGTAGAAG GACCTCCTCC CAAAGATACT GGCATTGCCC GAGTGCCACT TGCTGGAGCT 
GCTGGGGGGC CAGGCATCGG CAGGGCTGCT GGCAGAGGAA TCCCGGCGGG TGTGCCCATG 
CCCCAGGCTC CTGCAGGGCT TGCTGGACCA GTGCGAGGTG TTGGAGGGCC GTCCCAGCAG 
GTGATGACCC CACAAGGAAG AGGCACTGTG GCAGCTGCTG CAGCTGCAGC CACAGCCAGT 
ATTGCAGGAG CCCCAACTCA GTACCCACCT GGTCGTGGGG GTCCTCCTCC ACCTATGGGC 
CGAGGGGCAC CTCCTCCAGG TATGATGGGC CCACCTCCTG GCATGAGGCC TCCCATGGGT 
CCCCCAATGG GGATCCCTCC TGGCCGAGGA ACTCCAATGG GCATGCCCCC TCCTGGGATG 
CGACCTCCTC CTCCAGGCAT GCGAGGTCTG CTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation.
Cell170(4)701-713.e11(2017 Aug)
Bertram K,Agafonov DE,Dybkov O,Haselbach D,Leelaram MN,Will CL,Urlaub H,Kastner B,L?hrmann R,Stark H

Cryo-EM structure of a human spliceosome activated for step 2 of splicing.
Nature542(7641)318-323(2017 02)
Bertram K,Agafonov DE,Liu WT,Dybkov O,Will CL,Hartmuth K,Urlaub H,Kastner B,Stark H,L?hrmann R

Molecular architecture of the human U4/U6.U5 tri-snRNP.
Science (New York, N.Y.)351(6280)1416-20(2016 Mar)
Agafonov DE,Kastner B,Dybkov O,Hofele RV,Liu WT,Urlaub H,L?hrmann R,Stark H

Crystal structure of human U1 snRNP, a small nuclear ribonucleoprotein particle, reveals the mechanism of 5' splice site recognition.
eLife4(2015 Jan)
Kondo Y,Oubridge C,van Roon AM,Nagai K

Identification of novel deregulated RNA metabolism-related genes in non-small cell lung cancer.
PloS one7(8)e42086(2012)
Valles I,Pajares MJ,Segura V,Guruceaga E,Gomez-Roman J,Blanco D,Tamura A,Montuenga LM,Pio R