Slco1a2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Slco1a2
Entrez Gene ID	170698
Full Name	solute carrier organic anion transporter family, member 1A2
Synonyms	Oatp2,Slc21a5,Slco1a4
General protein information	Preferred Names solute carrier organic anion transporter family, member 1A2 Names solute carrier organic anion transporter family member 1A4 OATP-B1 brain digoxin carrier protein brain-specific organic anion transporter organic anion transporter 2 sodium-independent organic anion-transporting polypeptide 2 solute carrier family 21 (organic anion transporter), member 5 solute carrier family 21 member 5 solute carrier organic anion transporter family, member 1a4
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 4 Map Location: 4q44
Summary	mediates transport of a wide range of organic anions including bile acids, estrogen conjugates, ouabain, and digoxin; may be involved in digoxin toxicity [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_131906.1	NP_571981.1	solute carrier organic anion transporter family member 1A4
XM_017592412.1	XP_017447901.1	solute carrier organic anion transporter family member 1A4 isoform X1

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Slco1a2	NP_571981.1
Mus musculus (house mouse)	Slco1a4	NP_109612.1

Gene Ontology
Bibliography

Related articles in PubMed

Increased Renal Clearance of Rocuronium Compensates for Chronic Loss of Bile Excretion, via upregulation of Oatp2.
Wang L, Zhou MT, Chen CY, Yin W, Wen DX, Cheung CW, Yang LQ, Yu WF
Scientific reports740438(2017 Jan)

Organic anion transporting polypeptide 2 transports valproic acid in rat brain microvascular endothelial cells.
Guo Y, Jiang L
Neurological research38(7)634-9(2016 Jul)

Lack of Contribution of Multidrug Resistance-associated Protein and Organic Anion-transporting Polypeptide to Pharmacokinetics of Regorafenib, a Novel Multi-Kinase Inhibitor, in Rats.
Hotta K, Ueyama J, Tatsumi Y, Tsukiyama I, Sugiura Y, Saito H, Matsuura K, Hasegawa T
Anticancer research35(9)4681-9(2015 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

This study demostrated that transport of VPA is mediated by Oatp2. Oatp2 may play an important role in influencing the pharmacological activity of VPA by affecting its uptake and distribution in the brain.
Title: Organic anion transporting polypeptide 2 transports valproic acid in rat brain microvascular endothelial cells.

These findings suggest the possibility that ABCC2-mediated hepatobiliary excretion and OATP1/OATP2-mediated hepatic uptake do not play important roles in the disposition of regorafenib.
Title: Lack of Contribution of Multidrug Resistance-associated Protein and Organic Anion-transporting Polypeptide to Pharmacokinetics of Regorafenib, a Novel Multi-Kinase Inhibitor, in Rats.

Gene and protein expressions of analyzed transporters increase as the brain matures, with no variation in their activity for P-gp and bcrp, while the transport activity of oat3 and oatp1a4 increases during brain maturation from preterm up to adulthood.
Title: P-glycoprotein, breast cancer resistance protein, Organic Anion Transporter 3, and Transporting Peptide 1a4 during blood-brain barrier maturation: involvement of Wnt/?-catenin and endothelin-1 signaling.

In olfactory epithelium, high levels of expression of xenobiotic transporters Mrp1, Mrp3, Mrp5, Mdr1a, Oatp2 and Oat6 are expressed.
Title: Expression and differential localization of xenobiotic transporters in the rat olfactory neuro-epithelium.

Changes in Oatp1a4 functional expression suggest that inflammation in the periphery can modulate blood-brain barrier transporters.
Title: Inflammatory pain signals an increase in functional expression of organic anion transporting polypeptide 1a4 at the blood-brain barrier.

The following Slco1a2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Slco1a2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa00511	NM_131906.1 Latest version!	Rattus norvegicus solute carrier organic anion transporter family, member 1a4 (Slco1a4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa00511	XM_017592412.1 Latest version!	Rattus norvegicus solute carrier organic anion transporter family, member 1A2 (Slco1a2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Slco1a2 ( NM_131906.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_571981.1 Rattus norvegicus solute carrier organic anion transporter family, member 1a4 (Slco1a4), mRNA.

Price & Availability↑

CloneID	ORa00511
Clone ID Related Accession (Same CDS sequence)	NM_131906.1 , XM_017592412.1
Accession Version	NM_131906.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1986bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-16
Organism	Rattus norvegicus(Norway rat)
Product	solute carrier organic anion transporter family member 1A4
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from U88036.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U88036.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN04563758 [ECO:0000348] ##Evidence-Data-END##

ATGGGAAAAT CTGAGAAAAG GGTTGCAACC CATGGGGTCA GATGTTTTGC CAAGATCAAG 
ATGTTTCTGT TGGCATTAAC ATGTGCATAT GTATCCAAAT CATTATCAGG AACTTATATG 
AATTCCATGC TCACACAAAT AGAGAGACAA TTCGGTATCC CCACATCTAT AGTTGGGCTT 
ATCAATGGGA GCTTTGAAAT AGGAAACCTT TTGTTGATTA TATTTGTGAG TTATTTTGGA 
ACAAAACTTC ACAGACCTAT CATGATTGGT GTTGGATGTG CAGTTATGGG CCTGGGGTGT 
TTCTTAATCT CGCTACCCCA TTTCCTCATG GGCCAATATG AATATGAAAC GATTTTACCT 
ACAAGCAACG TGTCCTCAAA CAGCTTCTTC TGTGTGGAAA ACAGATCCCA GACCTTAAAT 
CCAACACAAG ACCCCTCAGA GTGTGTGAAA GAAATGAAAT CATTAATGTG GATATATGTA 
CTGGTAGGAA ACATAATACG TGGAATTGGT GAAACTCCCA TCATGCCCTT GGGTATTTCC 
TACATTGAAG ACTTTGCCAA ATCTGAAAAC TCTCCTTTAT ACATTGGGAT TTTAGAAACA 
GGAATGACCA TTGGCCCTTT GATTGGACTT CTGTTGGCTT CTTCCTGTGC AAACATTTAT 
GTAGACATTG AGTCTGTGAA TACAGATGAC CTGACCATAA CTCCCACAGA TACACGCTGG 
GTCGGAGCTT GGTGGATCGG CTTTTTGGTC TGTGCAGGAG TGAATATCCT GACCAGCTTT 
CCCTTTTTCT TTTTTCCCAA AACACTTCCA AAGGAAGGAT TACAGGAGAA TGTGGATGGA 
ACTGAAAATG CCAAAGAGAA GAAACACAGA AAAAAGGCCA AGGAAGAAAA ACGAGGAATC 
ACTAAAGATT TCTTTGTGTT CATGAAGAGC CTCTCCTGCA ATCCAATTTA CATGCTTTTC 
ATCCTTATAA GTGTTCTCCA GTTCAATGCA TTTATCAATT CATTTACCTT CATGCCTAAG 
TATCTGGAAC AGCAATATGG AAAATCCACT GCTGAGGTAG TCTTCCTTAT GGGTCTTTAT 
ATGTTACCTC CAATATGCCT CGGATATTTA ATTGGTGGTT TGATTATGAA GAAGTTCAAG 
GTTACTGTCA AGAAAGCTGC ACACTTAGCA TTCTGGCTCT GCCTGTCTGA GTACCTTCTG 
TCTTTCCTTA GCTATGTGAT GACCTGTGAT AATTTTCCAG TGGCAGGCTT AACAACCTCT 
TATGAAGGGG TTCAGCACCA ACTATATGTG GAGAACAAGG TCCTTGCTGA CTGTAACACA 
AGGTGTAACT GCTCAACGAA CACATGGGAT CCAGTGTGTG GAGACAATGG CCTGGCATAC 
ATGTCAGCCT GCCTTGCAGG CTGTGAGAAG TCTGTTGGAA CAGGAACCAA CATGGTGTTT 
CAGAATTGCA GCTGCATTCA GTCATCGGGA AACTCATCTG CAGTCCTGGG CCTGTGTAAC 
AAAGGCCCTG ACTGTGCCAA CAAGCTGCAG TACTTCTTAA TCATAGCAAT ATTTGGCTGT 
TTCATATACT CGCTGGCAGG CATTCCAGGG TATATGGTTC TTCTGAGGTG TATCAAGTCT 
GAAGAGAAGT CACTTGGAGT TGGGTTACAT GCATTTTGCA TAAGAATATT AGCTGGCATT 
CCTGCACCCA TTTACTTTGG AGCTTTGATA GACAGAACCT GTTTACATTG GGGAACCCTG 
AAATGTGGTG AGCCCGGGGC ATGCAGGATG TATGACATAA ACAGCTTCAG ACGTCTTTAC 
CTTGGATTGC CGGCTGCACT AAGAGGAGCA AGCTTTGTCC CCGCCTTCTT CATTCTAAGA 
CTTACGAGGA CATTCCAGTT CCCTGGGGAC ATTGAGTCTT CAAAAACTGA TCATGCGGAG 
ATGAAGCTCA CCTTGAAGGA AAGTGAGTGC ACAGAAGTCC TAAGGTCGAA AGTGACGGAG 
GACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_571981.1
CDS	119..2104
Translation	MGKSEKRVATHGVRCFAKIKMFLLALTCAYVSKSLSGTYMNSMLTQIERQFGIPTSIVGLINGSFEIGNLLLIIFVSYFGTKLHRPIMIGVGCAVMGLGCFLISLPHFLMGQYEYETILPTSNVSSNSFFCVENRSQTLNPTQDPSECVKEMKSLMWIYVLVGNIIRGIGETPIMPLGISYIEDFAKSENSPLYIGILETGMTIGPLIGLLLASSCANIYVDIESVNTDDLTITPTDTRWVGAWWIGFLVCAGVNILTSFPFFFFPKTLPKEGLQENVDGTENAKEKKHRKKAKEEKRGITKDFFVFMKSLSCNPIYMLFILISVLQFNAFINSFTFMPKYLEQQYGKSTAEVVFLMGLYMLPPICLGYLIGGLIMKKFKVTVKKAAHLAFWLCLSEYLLSFLSYVMTCDNFPVAGLTTSYEGVQHQLYVENKVLADCNTRCNCSTNTWDPVCGDNGLAYMSACLAGCEKSVGTGTNMVFQNCSCIQSSGNSSAVLGLCNKGPDCANKLQYFLIIAIFGCFIYSLAGIPGYMVLLRCIKSEEKSLGVGLHAFCIRILAGIPAPIYFGALIDRTCLHWGTLKCGEPGACRMYDINSFRRLYLGLPAALRGASFVPAFFILRLTRTFQFPGDIESSKTDHAEMKLTLKESECTEVLRSKVTED

Target ORF information:

RefSeq Version	NM_131906.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier organic anion transporter family, member 1a4 (Slco1a4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_131906.1

ORF Insert Sequence:

ATGGGAAAAT CTGAGAAAAG GGTTGCAACC CATGGGGTCA GATGTTTTGC CAAGATCAAG 
ATGTTTCTGT TGGCATTAAC ATGTGCATAT GTATCCAAAT CATTATCAGG AACTTATATG 
AATTCCATGC TCACACAAAT AGAGAGACAA TTCGGTATCC CCACATCTAT AGTTGGGCTT 
ATCAATGGGA GCTTTGAAAT AGGAAACCTT TTGTTGATTA TATTTGTGAG TTATTTTGGA 
ACAAAACTTC ACAGACCTAT CATGATTGGT GTTGGATGTG CAGTTATGGG CCTGGGGTGT 
TTCTTAATCT CGCTACCCCA TTTCCTCATG GGCCAATATG AATATGAAAC GATTTTACCT 
ACAAGCAACG TGTCCTCAAA CAGCTTCTTC TGTGTGGAAA ACAGATCCCA GACCTTAAAT 
CCAACACAAG ACCCCTCAGA GTGTGTGAAA GAAATGAAAT CATTAATGTG GATATATGTA 
CTGGTAGGAA ACATAATACG TGGAATTGGT GAAACTCCCA TCATGCCCTT GGGTATTTCC 
TACATTGAAG ACTTTGCCAA ATCTGAAAAC TCTCCTTTAT ACATTGGGAT TTTAGAAACA 
GGAATGACCA TTGGCCCTTT GATTGGACTT CTGTTGGCTT CTTCCTGTGC AAACATTTAT 
GTAGACATTG AGTCTGTGAA TACAGATGAC CTGACCATAA CTCCCACAGA TACACGCTGG 
GTCGGAGCTT GGTGGATCGG CTTTTTGGTC TGTGCAGGAG TGAATATCCT GACCAGCTTT 
CCCTTTTTCT TTTTTCCCAA AACACTTCCA AAGGAAGGAT TACAGGAGAA TGTGGATGGA 
ACTGAAAATG CCAAAGAGAA GAAACACAGA AAAAAGGCCA AGGAAGAAAA ACGAGGAATC 
ACTAAAGATT TCTTTGTGTT CATGAAGAGC CTCTCCTGCA ATCCAATTTA CATGCTTTTC 
ATCCTTATAA GTGTTCTCCA GTTCAATGCA TTTATCAATT CATTTACCTT CATGCCTAAG 
TATCTGGAAC AGCAATATGG AAAATCCACT GCTGAGGTAG TCTTCCTTAT GGGTCTTTAT 
ATGTTACCTC CAATATGCCT CGGATATTTA ATTGGTGGTT TGATTATGAA GAAGTTCAAG 
GTTACTGTCA AGAAAGCTGC ACACTTAGCA TTCTGGCTCT GCCTGTCTGA GTACCTTCTG 
TCTTTCCTTA GCTATGTGAT GACCTGTGAT AATTTTCCAG TGGCAGGCTT AACAACCTCT 
TATGAAGGGG TTCAGCACCA ACTATATGTG GAGAACAAGG TCCTTGCTGA CTGTAACACA 
AGGTGTAACT GCTCAACGAA CACATGGGAT CCAGTGTGTG GAGACAATGG CCTGGCATAC 
ATGTCAGCCT GCCTTGCAGG CTGTGAGAAG TCTGTTGGAA CAGGAACCAA CATGGTGTTT 
CAGAATTGCA GCTGCATTCA GTCATCGGGA AACTCATCTG CAGTCCTGGG CCTGTGTAAC 
AAAGGCCCTG ACTGTGCCAA CAAGCTGCAG TACTTCTTAA TCATAGCAAT ATTTGGCTGT 
TTCATATACT CGCTGGCAGG CATTCCAGGG TATATGGTTC TTCTGAGGTG TATCAAGTCT 
GAAGAGAAGT CACTTGGAGT TGGGTTACAT GCATTTTGCA TAAGAATATT AGCTGGCATT 
CCTGCACCCA TTTACTTTGG AGCTTTGATA GACAGAACCT GTTTACATTG GGGAACCCTG 
AAATGTGGTG AGCCCGGGGC ATGCAGGATG TATGACATAA ACAGCTTCAG ACGTCTTTAC 
CTTGGATTGC CGGCTGCACT AAGAGGAGCA AGCTTTGTCC CCGCCTTCTT CATTCTAAGA 
CTTACGAGGA CATTCCAGTT CCCTGGGGAC ATTGAGTCTT CAAAAACTGA TCATGCGGAG 
ATGAAGCTCA CCTTGAAGGA AAGTGAGTGC ACAGAAGTCC TAAGGTCGAA AGTGACGGAG 
GACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slco1a2 ( XM_017592412.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017447901.1 Rattus norvegicus solute carrier organic anion transporter family, member 1A2 (Slco1a2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa00511
Clone ID Related Accession (Same CDS sequence)	NM_131906.1 , XM_017592412.1
Accession Version	XM_017592412.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1986bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	solute carrier organic anion transporter family member 1A4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005103.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGAAAAT CTGAGAAAAG GGTTGCAACC CATGGGGTCA GATGTTTTGC CAAGATCAAG 
ATGTTTCTGT TGGCATTAAC ATGTGCATAT GTATCCAAAT CATTATCAGG AACTTATATG 
AATTCCATGC TCACACAAAT AGAGAGACAA TTCGGTATCC CCACATCTAT AGTTGGGCTT 
ATCAATGGGA GCTTTGAAAT AGGAAACCTT TTGTTGATTA TATTTGTGAG TTATTTTGGA 
ACAAAACTTC ACAGACCTAT CATGATTGGT GTTGGATGTG CAGTTATGGG CCTGGGGTGT 
TTCTTAATCT CGCTACCCCA TTTCCTCATG GGCCAATATG AATATGAAAC GATTTTACCT 
ACAAGCAACG TGTCCTCAAA CAGCTTCTTC TGTGTGGAAA ACAGATCCCA GACCTTAAAT 
CCAACACAAG ACCCCTCAGA GTGTGTGAAA GAAATGAAAT CATTAATGTG GATATATGTA 
CTGGTAGGAA ACATAATACG TGGAATTGGT GAAACTCCCA TCATGCCCTT GGGTATTTCC 
TACATTGAAG ACTTTGCCAA ATCTGAAAAC TCTCCTTTAT ACATTGGGAT TTTAGAAACA 
GGAATGACCA TTGGCCCTTT GATTGGACTT CTGTTGGCTT CTTCCTGTGC AAACATTTAT 
GTAGACATTG AGTCTGTGAA TACAGATGAC CTGACCATAA CTCCCACAGA TACACGCTGG 
GTCGGAGCTT GGTGGATCGG CTTTTTGGTC TGTGCAGGAG TGAATATCCT GACCAGCTTT 
CCCTTTTTCT TTTTTCCCAA AACACTTCCA AAGGAAGGAT TACAGGAGAA TGTGGATGGA 
ACTGAAAATG CCAAAGAGAA GAAACACAGA AAAAAGGCCA AGGAAGAAAA ACGAGGAATC 
ACTAAAGATT TCTTTGTGTT CATGAAGAGC CTCTCCTGCA ATCCAATTTA CATGCTTTTC 
ATCCTTATAA GTGTTCTCCA GTTCAATGCA TTTATCAATT CATTTACCTT CATGCCTAAG 
TATCTGGAAC AGCAATATGG AAAATCCACT GCTGAGGTAG TCTTCCTTAT GGGTCTTTAT 
ATGTTACCTC CAATATGCCT CGGATATTTA ATTGGTGGTT TGATTATGAA GAAGTTCAAG 
GTTACTGTCA AGAAAGCTGC ACACTTAGCA TTCTGGCTCT GCCTGTCTGA GTACCTTCTG 
TCTTTCCTTA GCTATGTGAT GACCTGTGAT AATTTTCCAG TGGCAGGCTT AACAACCTCT 
TATGAAGGGG TTCAGCACCA ACTATATGTG GAGAACAAGG TCCTTGCTGA CTGTAACACA 
AGGTGTAACT GCTCAACGAA CACATGGGAT CCAGTGTGTG GAGACAATGG CCTGGCATAC 
ATGTCAGCCT GCCTTGCAGG CTGTGAGAAG TCTGTTGGAA CAGGAACCAA CATGGTGTTT 
CAGAATTGCA GCTGCATTCA GTCATCGGGA AACTCATCTG CAGTCCTGGG CCTGTGTAAC 
AAAGGCCCTG ACTGTGCCAA CAAGCTGCAG TACTTCTTAA TCATAGCAAT ATTTGGCTGT 
TTCATATACT CGCTGGCAGG CATTCCAGGG TATATGGTTC TTCTGAGGTG TATCAAGTCT 
GAAGAGAAGT CACTTGGAGT TGGGTTACAT GCATTTTGCA TAAGAATATT AGCTGGCATT 
CCTGCACCCA TTTACTTTGG AGCTTTGATA GACAGAACCT GTTTACATTG GGGAACCCTG 
AAATGTGGTG AGCCCGGGGC ATGCAGGATG TATGACATAA ACAGCTTCAG ACGTCTTTAC 
CTTGGATTGC CGGCTGCACT AAGAGGAGCA AGCTTTGTCC CCGCCTTCTT CATTCTAAGA 
CTTACGAGGA CATTCCAGTT CCCTGGGGAC ATTGAGTCTT CAAAAACTGA TCATGCGGAG 
ATGAAGCTCA CCTTGAAGGA AAGTGAGTGC ACAGAAGTCC TAAGGTCGAA AGTGACGGAG 
GACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017447901.1
CDS	313..2298
Translation	MGKSEKRVATHGVRCFAKIKMFLLALTCAYVSKSLSGTYMNSMLTQIERQFGIPTSIVGLINGSFEIGNLLLIIFVSYFGTKLHRPIMIGVGCAVMGLGCFLISLPHFLMGQYEYETILPTSNVSSNSFFCVENRSQTLNPTQDPSECVKEMKSLMWIYVLVGNIIRGIGETPIMPLGISYIEDFAKSENSPLYIGILETGMTIGPLIGLLLASSCANIYVDIESVNTDDLTITPTDTRWVGAWWIGFLVCAGVNILTSFPFFFFPKTLPKEGLQENVDGTENAKEKKHRKKAKEEKRGITKDFFVFMKSLSCNPIYMLFILISVLQFNAFINSFTFMPKYLEQQYGKSTAEVVFLMGLYMLPPICLGYLIGGLIMKKFKVTVKKAAHLAFWLCLSEYLLSFLSYVMTCDNFPVAGLTTSYEGVQHQLYVENKVLADCNTRCNCSTNTWDPVCGDNGLAYMSACLAGCEKSVGTGTNMVFQNCSCIQSSGNSSAVLGLCNKGPDCANKLQYFLIIAIFGCFIYSLAGIPGYMVLLRCIKSEEKSLGVGLHAFCIRILAGIPAPIYFGALIDRTCLHWGTLKCGEPGACRMYDINSFRRLYLGLPAALRGASFVPAFFILRLTRTFQFPGDIESSKTDHAEMKLTLKESECTEVLRSKVTED

Target ORF information:

RefSeq Version	XM_017592412.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier organic anion transporter family, member 1A2 (Slco1a2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017592412.1

ORF Insert Sequence:

ATGGGAAAAT CTGAGAAAAG GGTTGCAACC CATGGGGTCA GATGTTTTGC CAAGATCAAG 
ATGTTTCTGT TGGCATTAAC ATGTGCATAT GTATCCAAAT CATTATCAGG AACTTATATG 
AATTCCATGC TCACACAAAT AGAGAGACAA TTCGGTATCC CCACATCTAT AGTTGGGCTT 
ATCAATGGGA GCTTTGAAAT AGGAAACCTT TTGTTGATTA TATTTGTGAG TTATTTTGGA 
ACAAAACTTC ACAGACCTAT CATGATTGGT GTTGGATGTG CAGTTATGGG CCTGGGGTGT 
TTCTTAATCT CGCTACCCCA TTTCCTCATG GGCCAATATG AATATGAAAC GATTTTACCT 
ACAAGCAACG TGTCCTCAAA CAGCTTCTTC TGTGTGGAAA ACAGATCCCA GACCTTAAAT 
CCAACACAAG ACCCCTCAGA GTGTGTGAAA GAAATGAAAT CATTAATGTG GATATATGTA 
CTGGTAGGAA ACATAATACG TGGAATTGGT GAAACTCCCA TCATGCCCTT GGGTATTTCC 
TACATTGAAG ACTTTGCCAA ATCTGAAAAC TCTCCTTTAT ACATTGGGAT TTTAGAAACA 
GGAATGACCA TTGGCCCTTT GATTGGACTT CTGTTGGCTT CTTCCTGTGC AAACATTTAT 
GTAGACATTG AGTCTGTGAA TACAGATGAC CTGACCATAA CTCCCACAGA TACACGCTGG 
GTCGGAGCTT GGTGGATCGG CTTTTTGGTC TGTGCAGGAG TGAATATCCT GACCAGCTTT 
CCCTTTTTCT TTTTTCCCAA AACACTTCCA AAGGAAGGAT TACAGGAGAA TGTGGATGGA 
ACTGAAAATG CCAAAGAGAA GAAACACAGA AAAAAGGCCA AGGAAGAAAA ACGAGGAATC 
ACTAAAGATT TCTTTGTGTT CATGAAGAGC CTCTCCTGCA ATCCAATTTA CATGCTTTTC 
ATCCTTATAA GTGTTCTCCA GTTCAATGCA TTTATCAATT CATTTACCTT CATGCCTAAG 
TATCTGGAAC AGCAATATGG AAAATCCACT GCTGAGGTAG TCTTCCTTAT GGGTCTTTAT 
ATGTTACCTC CAATATGCCT CGGATATTTA ATTGGTGGTT TGATTATGAA GAAGTTCAAG 
GTTACTGTCA AGAAAGCTGC ACACTTAGCA TTCTGGCTCT GCCTGTCTGA GTACCTTCTG 
TCTTTCCTTA GCTATGTGAT GACCTGTGAT AATTTTCCAG TGGCAGGCTT AACAACCTCT 
TATGAAGGGG TTCAGCACCA ACTATATGTG GAGAACAAGG TCCTTGCTGA CTGTAACACA 
AGGTGTAACT GCTCAACGAA CACATGGGAT CCAGTGTGTG GAGACAATGG CCTGGCATAC 
ATGTCAGCCT GCCTTGCAGG CTGTGAGAAG TCTGTTGGAA CAGGAACCAA CATGGTGTTT 
CAGAATTGCA GCTGCATTCA GTCATCGGGA AACTCATCTG CAGTCCTGGG CCTGTGTAAC 
AAAGGCCCTG ACTGTGCCAA CAAGCTGCAG TACTTCTTAA TCATAGCAAT ATTTGGCTGT 
TTCATATACT CGCTGGCAGG CATTCCAGGG TATATGGTTC TTCTGAGGTG TATCAAGTCT 
GAAGAGAAGT CACTTGGAGT TGGGTTACAT GCATTTTGCA TAAGAATATT AGCTGGCATT 
CCTGCACCCA TTTACTTTGG AGCTTTGATA GACAGAACCT GTTTACATTG GGGAACCCTG 
AAATGTGGTG AGCCCGGGGC ATGCAGGATG TATGACATAA ACAGCTTCAG ACGTCTTTAC 
CTTGGATTGC CGGCTGCACT AAGAGGAGCA AGCTTTGTCC CCGCCTTCTT CATTCTAAGA 
CTTACGAGGA CATTCCAGTT CCCTGGGGAC ATTGAGTCTT CAAAAACTGA TCATGCGGAG 
ATGAAGCTCA CCTTGAAGGA AAGTGAGTGC ACAGAAGTCC TAAGGTCGAA AGTGACGGAG 
GACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Increased Renal Clearance of Rocuronium Compensates for Chronic Loss of Bile Excretion, via upregulation of Oatp2.
Scientific reports740438(2017 Jan)
Wang L,Zhou MT,Chen CY,Yin W,Wen DX,Cheung CW,Yang LQ,Yu WF

Organic anion transporting polypeptide 2 transports valproic acid in rat brain microvascular endothelial cells.
Neurological research38(7)634-9(2016 Jul)
Guo Y,Jiang L

Lack of Contribution of Multidrug Resistance-associated Protein and Organic Anion-transporting Polypeptide to Pharmacokinetics of Regorafenib, a Novel Multi-Kinase Inhibitor, in Rats.
Anticancer research35(9)4681-9(2015 Sep)
Hotta K,Ueyama J,Tatsumi Y,Tsukiyama I,Sugiura Y,Saito H,Matsuura K,Hasegawa T

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Slco1a2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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