Mmp12 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Mmp12
Entrez Gene ID	117033
Full Name	matrix metallopeptidase 12
Synonyms	Mme
General protein information	Preferred Names matrix metallopeptidase 12 Names macrophage metalloelastase MMP-12 matrix metalloproteinase-12
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 8 Map Location: 8q11
Summary	a macrophage metalloelastase/matrix metalloproteinase; may have a role in glomerular injury in a crescentic glomerulonephritis [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_017595420.1	XP_017450909.1	macrophage metalloelastase isoform X1
NM_053963.2	NP_446415.2	macrophage metalloelastase preproprotein

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	MMP12	XP_854594.2
Homo sapiens (human)	MMP12	NP_002417.2
Pan troglodytes (chimpanzee)	MMP12	XP_508724.2
Bos taurus (cattle)	MMP12	NP_001193569.1
	MMP12	XP_001098589.1
Mus musculus (house mouse)	Mmp12	NP_032631.3
Rattus norvegicus (Norway rat)	Mmp12	NP_446415.2

Gene Ontology
Bibliography

Related articles in PubMed

Gingival Tissue Inflammation Promotes Increased Matrix Metalloproteinase-12 Production by CD200R
Bj?rnfot Holmstr?m S, Clark R, Zwicker S, Bureik D, Kvedaraite E, Bernasconi E, Nguyen Hoang AT, Johannsen G, Marsland BJ, Bostr?m EA, Svensson M
Journal of immunology (Baltimore, Md. : 1950)199(12)4023-4035(2017 Dec)

HIF-KDM3A-MMP12 regulatory circuit ensures trophoblast plasticity and placental adaptations to hypoxia.
Chakraborty D, Cui W, Rosario GX, Scott RL, Dhakal P, Renaud SJ, Tachibana M, Rumi MA, Mason CW, Krieg AJ, Soares MJ
Proceedings of the National Academy of Sciences of the United States of America113(46)E7212-E7221(2016 Nov)

Matrix Metalloproteinase-12 Induces Blood-Brain Barrier Damage After Focal Cerebral Ischemia.
Chelluboina B, Klopfenstein JD, Pinson DM, Wang DZ, Vemuganti R, Veeravalli KK
Stroke46(12)3523-31(2015 Dec)

Post-transcriptional inactivation of matrix metalloproteinase-12 after focal cerebral ischemia attenuates brain damage.
Chelluboina B, Warhekar A, Dillard M, Klopfenstein JD, Pinson DM, Wang DZ, Veeravalli KK
Scientific reports59504(2015 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

MMP-12 plays an adverse role in acute brain damage occurring after ischemic stroke.
Title: Matrix Metalloproteinase-12 Induces Blood-Brain Barrier Damage After Focal Cerebral Ischemia.

Specific knockdown of MMP-12 after focal cerebral ischemia offers neuroprotection.
Title: Post-transcriptional inactivation of matrix metalloproteinase-12 after focal cerebral ischemia attenuates brain damage.

Inspiratory resistive breathing induces MMP-9 and -12 in the lung of previously healthy rats.
Title: Inspiratory resistive breathing induces MMP-9 and MMP-12 expression in the lung.

MMP12 upregulated in regenerating motor neurons of the mouse and rat facial nucleus; findings point to a role of MMP12 in the neuronal initiation of the synaptic stripping process
Title: Up-regulation of matrix metallopeptidase 12 in motor neurons undergoing synaptic stripping.

MMP-8, MMP-9 and MMP-12 gene and protein expression increased profoundly (p < 0.01), and MMP-13 mRNA and MMP-2 mRNA and protein modestly (p < 0.001) in the anastomoses.
Title: Expression and inhibition of matrix metalloproteinase (MMP)-8, MMP-9 and MMP-12 in early colonic anastomotic repair.

The following Mmp12 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Mmp12 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa12138	NM_053963.2 Latest version!	Rattus norvegicus matrix metallopeptidase 12 (Mmp12), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$272.30 $389.00
ORa62282	XM_017595420.1 Latest version!	Rattus norvegicus matrix metallopeptidase 12 (Mmp12), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Mmp12 ( NM_053963.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_446415.2 Rattus norvegicus matrix metallopeptidase 12 (Mmp12), mRNA.

Price & Availability↑

CloneID	ORa12138
Clone ID Related Accession (Same CDS sequence)	NM_053963.2
Accession Version	NM_053963.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1434bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-21
Organism	Rattus norvegicus(Norway rat)
Product	macrophage metalloelastase preproprotein
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC088120.1 and CB791502.1. On Mar 23, 2010 this sequence version replaced NM_053963.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC088120.1, X98517.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689599, SAMEA2689602 [ECO:0000348] ##Evidence-Data-END##

ATGAACTGGA CTCTGTTGCT GAAAGGAGCT GGCACAATGA AGTTTCTCCT CGTGCTGGTG 
CTGCTTGTGT CCTTACAGGT ATCTGCCTGT GGGGCTGCTC CCATGAACGA GAGCGAATTT 
GCTGAATGGT ACTTGTCAAG ATTTTTTGAC TATCAAGGGG ACAGAATTCC AATGACAAAA 
ACAAAAACCA ATAGAAACCT CCTAGAAGAA AAACTCCAGG AAATGCAGCA GTTCTTTGGG 
CTAGAAGTAA CTGGGCAACT GGACACCTCA ACTCTGAAAA TAATGCACAC GTCTCGATGT 
GGAGTGCCTG ATGTACAGCA TCTTAGAGCA GTGCCCCAGA GGTCAAGATG GATGAAGCGG 
TATCTCACTT ACAGGATCTA TAATTACACT CCAGACATGA AGCGTGCGGA TGTAGACTAC 
ATATTTCAGA AAGCTTTTCA AGTCTGGAGC GATGTCACTC CTCTAAGATT CAGAAAGATT 
CATAAAGGCG AGGCTGACAT TACGATACTT TTTGCATTTG GAGATCATGG AGACTTCTAC 
GATTTTGATG GCAAAGGTGG TACCTTAGCC CATGCTTTTT ATCCTGGGCC CGGTATTCAA 
GGAGATGCAC ATTTTGATGA GGCAGAAACC TGGACTAAAA GTTTTCAAGG CACAAACCTG 
TTCCTTGTTG CTGTTCATGA GCTTGGCCAT TCCTTGGGGC TGCCGCATTC CAATAATCCA 
AAATCAATAA TGTACCCTAC CTACAGATAC CTTCACCCCA ACACATTTCG TCTCTCTGCT 
GATGACATAC ACAGCATTCA GTCCCTCTAC GGAGCCCCAG TGAAAAACCC ATCCTTGACA 
AATCCTGGAA GTCCACCATC AACTGTGTGT CACCAAAGCT TGAGTTTTGA TGCTGTCACA 
ACAGTGGGAG ATAAAATCTT TTTCTTTAAA GACTGGTTCT TCTGGTGGAG GCTGCCTGGG 
AGTCCAGCCA CCAACATTAC TTCAATTTCT TCCATGTGGC CAACTATCCC ATCTGGTATT 
CAAGCTGCTT ATGAAATTGG AGGCAGAAAT CAACTTTTTC TTTTTAAAGA TGAGAAGTAC 
TGGTTAATAA ACAACTTGGT ACCAGAGCCA CACTATCCCA GAAGCATACA TTCTCTGGGC 
TTCCCTGCAT CTGTAAAGAA GATTGATGCA GCTGTCTTTG ATCCACTTCG CCAAAAGGTC 
TATTTCTTTG TGGATAAACA ATATTGGAGG TACGATGTGA GGCAGGAACT CATGGACGCT 
GCTTACCCCA AGCTGATTTC TACACACTTC CCAGGAATCA GGCCAAAAAT TGATGCAGTT 
CTCTATTTCA AAAGGCACTA CTACATCTTC CAAGGAGCCT ACCAATTGGA ATATGACCCC 
TTACTGCATC GTGTCACCAA AACATTGAGC AGTACGAGCT GGTTCGGTTG TTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_446415.2
CDS	9..1442
Translation	MNWTLLLKGAGTMKFLLVLVLLVSLQVSACGAAPMNESEFAEWYLSRFFDYQGDRIPMTKTKTNRNLLEEKLQEMQQFFGLEVTGQLDTSTLKIMHTSRCGVPDVQHLRAVPQRSRWMKRYLTYRIYNYTPDMKRADVDYIFQKAFQVWSDVTPLRFRKIHKGEADITILFAFGDHGDFYDFDGKGGTLAHAFYPGPGIQGDAHFDEAETWTKSFQGTNLFLVAVHELGHSLGLPHSNNPKSIMYPTYRYLHPNTFRLSADDIHSIQSLYGAPVKNPSLTNPGSPPSTVCHQSLSFDAVTTVGDKIFFFKDWFFWWRLPGSPATNITSISSMWPTIPSGIQAAYEIGGRNQLFLFKDEKYWLINNLVPEPHYPRSIHSLGFPASVKKIDAAVFDPLRQKVYFFVDKQYWRYDVRQELMDAAYPKLISTHFPGIRPKIDAVLYFKRHYYIFQGAYQLEYDPLLHRVTKTLSSTSWFGC

Target ORF information:

RefSeq Version	NM_053963.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus matrix metallopeptidase 12 (Mmp12), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_053963.2

ORF Insert Sequence:

ATGAACTGGA CTCTGTTGCT GAAAGGAGCT GGCACAATGA AGTTTCTCCT CGTGCTGGTG 
CTGCTTGTGT CCTTACAGGT ATCTGCCTGT GGGGCTGCTC CCATGAACGA GAGCGAATTT 
GCTGAATGGT ACTTGTCAAG ATTTTTTGAC TATCAAGGGG ACAGAATTCC AATGACAAAA 
ACAAAAACCA ATAGAAACCT CCTAGAAGAA AAACTCCAGG AAATGCAGCA GTTCTTTGGG 
CTAGAAGTAA CTGGGCAACT GGACACCTCA ACTCTGAAAA TAATGCACAC GTCTCGATGT 
GGAGTGCCTG ATGTACAGCA TCTTAGAGCA GTGCCCCAGA GGTCAAGATG GATGAAGCGG 
TATCTCACTT ACAGGATCTA TAATTACACT CCAGACATGA AGCGTGCGGA TGTAGACTAC 
ATATTTCAGA AAGCTTTTCA AGTCTGGAGC GATGTCACTC CTCTAAGATT CAGAAAGATT 
CATAAAGGCG AGGCTGACAT TACGATACTT TTTGCATTTG GAGATCATGG AGACTTCTAC 
GATTTTGATG GCAAAGGTGG TACCTTAGCC CATGCTTTTT ATCCTGGGCC CGGTATTCAA 
GGAGATGCAC ATTTTGATGA GGCAGAAACC TGGACTAAAA GTTTTCAAGG CACAAACCTG 
TTCCTTGTTG CTGTTCATGA GCTTGGCCAT TCCTTGGGGC TGCCGCATTC CAATAATCCA 
AAATCAATAA TGTACCCTAC CTACAGATAC CTTCACCCCA ACACATTTCG TCTCTCTGCT 
GATGACATAC ACAGCATTCA GTCCCTCTAC GGAGCCCCAG TGAAAAACCC ATCCTTGACA 
AATCCTGGAA GTCCACCATC AACTGTGTGT CACCAAAGCT TGAGTTTTGA TGCTGTCACA 
ACAGTGGGAG ATAAAATCTT TTTCTTTAAA GACTGGTTCT TCTGGTGGAG GCTGCCTGGG 
AGTCCAGCCA CCAACATTAC TTCAATTTCT TCCATGTGGC CAACTATCCC ATCTGGTATT 
CAAGCTGCTT ATGAAATTGG AGGCAGAAAT CAACTTTTTC TTTTTAAAGA TGAGAAGTAC 
TGGTTAATAA ACAACTTGGT ACCAGAGCCA CACTATCCCA GAAGCATACA TTCTCTGGGC 
TTCCCTGCAT CTGTAAAGAA GATTGATGCA GCTGTCTTTG ATCCACTTCG CCAAAAGGTC 
TATTTCTTTG TGGATAAACA ATATTGGAGG TACGATGTGA GGCAGGAACT CATGGACGCT 
GCTTACCCCA AGCTGATTTC TACACACTTC CCAGGAATCA GGCCAAAAAT TGATGCAGTT 
CTCTATTTCA AAAGGCACTA CTACATCTTC CAAGGAGCCT ACCAATTGGA ATATGACCCC 
TTACTGCATC GTGTCACCAA AACATTGAGC AGTACGAGCT GGTTCGGTTG TTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mmp12 ( XM_017595420.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017450909.1 Rattus norvegicus matrix metallopeptidase 12 (Mmp12), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa62282
Clone ID Related Accession (Same CDS sequence)	XM_017595420.1
Accession Version	XM_017595420.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1263bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	macrophage metalloelastase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005107.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACAAAAA CAAAAACCAA TAGAAACCTC CTAGAAGAAA AACTCCAGGA AATGCAGCAG 
TTCTTTGGGC TAGAAGTAAC TGGGCAACTG GACACCTCAA CTCTGAAAAT AATGCACACG 
TCTCGATGTG GAGTGCCTGA TGTACAGCAT CTTAGAGCAG TGCCCCAGAG GTCAAGATGG 
ATGAAGCGGT ATCTCACTTA CAGGATCTAT AATTACACTC CAGACATGAA GCGTGCGGAT 
GTAGACTACA TATTTCAGAA AGCTTTTCAA GTCTGGAGCG ATGTCACTCC TCTAAGATTC 
AGAAAGATTC ATAAAGGCGA GGCTGACATT ACGATACTTT TTGCATTTGG AGATCATGGA 
GACTTCTACG ATTTTGATGG CAAAGGTGGT ACCTTAGCCC ATGCTTTTTA TCCTGGGCCC 
GGTATTCAAG GAGATGCACA TTTTGATGAG GCAGAAACCT GGACTAAAAG TTTTCAAGGC 
ACAAACCTGT TCCTTGTTGC TGTTCATGAG CTTGGCCATT CCTTGGGGCT GCCGCATTCC 
AATAATCCAA AATCAATAAT GTACCCTACC TACAGATACC TTCACCCCAA CACATTTCGT 
CTCTCTGCTG ATGACATACA CAGCATTCAG TCCCTCTACG GAGCCCCAGT GAAAAACCCA 
TCCTTGACAA ATCCTGGAAG TCCACCATCA ACTGTGTGTC ACCAAAGCTT GAGTTTTGAT 
GCTGTCACAA CAGTGGGAGA TAAAATCTTT TTCTTTAAAG ACTGGTTCTT CTGGTGGAGG 
CTGCCTGGGA GTCCAGCCAC CAACATTACT TCAATTTCTT CCATGTGGCC AACTATCCCA 
TCTGGTATTC AAGCTGCTTA TGAAATTGGA GGCAGAAATC AACTTTTTCT TTTTAAAGAT 
GAGAAGTACT GGTTAATAAA CAACTTGGTA CCAGAGCCAC ACTATCCCAG AAGCATACAT 
TCTCTGGGCT TCCCTGCATC TGTAAAGAAG ATTGATGCAG CTGTCTTTGA TCCACTTCGC 
CAAAAGGTCT ATTTCTTTGT GGATAAACAA TATTGGAGGT ACGATGTGAG GCAGGAACTC 
ATGGACGCTG CTTACCCCAA GCTGATTTCT ACACACTTCC CAGGAATCAG GCCAAAAATT 
GATGCAGTTC TCTATTTCAA AAGGCACTAC TACATCTTCC AAGGAGCCTA CCAATTGGAA 
TATGACCCCT TACTGCATCG TGTCACCAAA ACATTGAGCA GTACGAGCTG GTTCGGTTGT 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017450909.1
CDS	138..1400
Translation	MTKTKTNRNLLEEKLQEMQQFFGLEVTGQLDTSTLKIMHTSRCGVPDVQHLRAVPQRSRWMKRYLTYRIYNYTPDMKRADVDYIFQKAFQVWSDVTPLRFRKIHKGEADITILFAFGDHGDFYDFDGKGGTLAHAFYPGPGIQGDAHFDEAETWTKSFQGTNLFLVAVHELGHSLGLPHSNNPKSIMYPTYRYLHPNTFRLSADDIHSIQSLYGAPVKNPSLTNPGSPPSTVCHQSLSFDAVTTVGDKIFFFKDWFFWWRLPGSPATNITSISSMWPTIPSGIQAAYEIGGRNQLFLFKDEKYWLINNLVPEPHYPRSIHSLGFPASVKKIDAAVFDPLRQKVYFFVDKQYWRYDVRQELMDAAYPKLISTHFPGIRPKIDAVLYFKRHYYIFQGAYQLEYDPLLHRVTKTLSSTSWFGC

Target ORF information:

RefSeq Version	XM_017595420.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus matrix metallopeptidase 12 (Mmp12), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017595420.1

ORF Insert Sequence:

ATGACAAAAA CAAAAACCAA TAGAAACCTC CTAGAAGAAA AACTCCAGGA AATGCAGCAG 
TTCTTTGGGC TAGAAGTAAC TGGGCAACTG GACACCTCAA CTCTGAAAAT AATGCACACG 
TCTCGATGTG GAGTGCCTGA TGTACAGCAT CTTAGAGCAG TGCCCCAGAG GTCAAGATGG 
ATGAAGCGGT ATCTCACTTA CAGGATCTAT AATTACACTC CAGACATGAA GCGTGCGGAT 
GTAGACTACA TATTTCAGAA AGCTTTTCAA GTCTGGAGCG ATGTCACTCC TCTAAGATTC 
AGAAAGATTC ATAAAGGCGA GGCTGACATT ACGATACTTT TTGCATTTGG AGATCATGGA 
GACTTCTACG ATTTTGATGG CAAAGGTGGT ACCTTAGCCC ATGCTTTTTA TCCTGGGCCC 
GGTATTCAAG GAGATGCACA TTTTGATGAG GCAGAAACCT GGACTAAAAG TTTTCAAGGC 
ACAAACCTGT TCCTTGTTGC TGTTCATGAG CTTGGCCATT CCTTGGGGCT GCCGCATTCC 
AATAATCCAA AATCAATAAT GTACCCTACC TACAGATACC TTCACCCCAA CACATTTCGT 
CTCTCTGCTG ATGACATACA CAGCATTCAG TCCCTCTACG GAGCCCCAGT GAAAAACCCA 
TCCTTGACAA ATCCTGGAAG TCCACCATCA ACTGTGTGTC ACCAAAGCTT GAGTTTTGAT 
GCTGTCACAA CAGTGGGAGA TAAAATCTTT TTCTTTAAAG ACTGGTTCTT CTGGTGGAGG 
CTGCCTGGGA GTCCAGCCAC CAACATTACT TCAATTTCTT CCATGTGGCC AACTATCCCA 
TCTGGTATTC AAGCTGCTTA TGAAATTGGA GGCAGAAATC AACTTTTTCT TTTTAAAGAT 
GAGAAGTACT GGTTAATAAA CAACTTGGTA CCAGAGCCAC ACTATCCCAG AAGCATACAT 
TCTCTGGGCT TCCCTGCATC TGTAAAGAAG ATTGATGCAG CTGTCTTTGA TCCACTTCGC 
CAAAAGGTCT ATTTCTTTGT GGATAAACAA TATTGGAGGT ACGATGTGAG GCAGGAACTC 
ATGGACGCTG CTTACCCCAA GCTGATTTCT ACACACTTCC CAGGAATCAG GCCAAAAATT 
GATGCAGTTC TCTATTTCAA AAGGCACTAC TACATCTTCC AAGGAGCCTA CCAATTGGAA 
TATGACCCCT TACTGCATCG TGTCACCAAA ACATTGAGCA GTACGAGCTG GTTCGGTTGT 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gingival Tissue Inflammation Promotes Increased Matrix Metalloproteinase-12 Production by CD200R
Journal of immunology (Baltimore, Md. : 1950)199(12)4023-4035(2017 Dec)
Bj?rnfot Holmstr?m S,Clark R,Zwicker S,Bureik D,Kvedaraite E,Bernasconi E,Nguyen Hoang AT,Johannsen G,Marsland BJ,Bostr?m EA,Svensson M

HIF-KDM3A-MMP12 regulatory circuit ensures trophoblast plasticity and placental adaptations to hypoxia.
Proceedings of the National Academy of Sciences of the United States of America113(46)E7212-E7221(2016 Nov)
Chakraborty D,Cui W,Rosario GX,Scott RL,Dhakal P,Renaud SJ,Tachibana M,Rumi MA,Mason CW,Krieg AJ,Soares MJ

Matrix Metalloproteinase-12 Induces Blood-Brain Barrier Damage After Focal Cerebral Ischemia.
Stroke46(12)3523-31(2015 Dec)
Chelluboina B,Klopfenstein JD,Pinson DM,Wang DZ,Vemuganti R,Veeravalli KK

Post-transcriptional inactivation of matrix metalloproteinase-12 after focal cerebral ischemia attenuates brain damage.
Scientific reports59504(2015 May)
Chelluboina B,Warhekar A,Dillard M,Klopfenstein JD,Pinson DM,Wang DZ,Veeravalli KK

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Mmp12 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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