Sorcs2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Sorcs2
Entrez Gene ID	81840
Full Name	sortilin-related VPS10 domain containing receptor 2
Synonyms	N28137,mKIAA1329
General protein information	Preferred Names sortilin-related VPS10 domain containing receptor 2 Names VPS10 domain-containing receptor SorCS2 VPS10 domain receptor protein SORCS 2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 5 Map Location: 5\|5 B3

mRNA and Protein(s)

mRNA	Protein	Name
XM_006504202.3	XP_006504265.1	VPS10 domain-containing receptor SorCS2 isoform X1
NM_030889.2	NP_112151.2	VPS10 domain-containing receptor SorCS2 precursor
XM_006504202.4	XP_006504265.1	VPS10 domain-containing receptor SorCS2 isoform X1
XM_030254926.1	XP_030110786.1	VPS10 domain-containing receptor SorCS2 isoform X2

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	sorcs2	XP_002662899.3
Pan troglodytes (chimpanzee)	SORCS2	XP_003310293.2
Gallus gallus (chicken)	SORCS2	XP_426353.4
Xenopus tropicalis (tropical clawed frog)	sorcs2	XP_002938309.2
Bos taurus (cattle)	SORCS2	XP_003586285.2
Rattus norvegicus (Norway rat)	Sorcs2	NP_001100695.2
Homo sapiens (human)	SORCS2	NP_065828.2
Canis lupus familiaris (dog)	SORCS2	XP_005618511.1
Mus musculus (house mouse)	Sorcs2	NP_112151.2

Gene Ontology
Bibliography

Related articles in PubMed

SorCS2-mediated NR2A trafficking regulates motor deficits in Huntington's disease.
Ma Q, Yang J, Milner TA, Vonsattel JG, Palko ME, Tessarollo L, Hempstead BL
JCI insight2(9)(2017 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Results indicate that hearing loss and hair bundle defects are associated with SorCS2 (Sortilin-related VPS-10 domain containing protein) disruption.
Title: Disruption of SorCS2 reveals differences in the regulation of stereociliary bundle formation between hair cell types in the inner ear.

SorCS2 is expressed in mesodermally derived tissues such as striated muscle, adipose tissue, ossifying bone and connective tissue.
Title: Spatiotemporal patterns of sortilin and SorCS2 localization during organ development.

SorCS3 and the homologous sorCS1 and sorCS2 genes were expressed in a combinatorial mostly non-overlapping pattern in the developing and mature central nervous system; activity-dependent induction of sorCS3 did not require protein synthesis
Title: The three sorCS genes are differentially expressed and regulated by synaptic activity.

The following Sorcs2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Sorcs2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu89049	XM_030254926.1 Latest version!	Mus musculus sortilin-related VPS10 domain containing receptor 2 (Sorcs2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
OMu35271	XM_006504202.4 Latest version!	Mus musculus sortilin-related VPS10 domain containing receptor 2 (Sorcs2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$559.30 $799.00
OMu08478	NM_030889.2 Latest version!	Mus musculus sortilin-related VPS10 domain containing receptor 2 (Sorcs2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$678.30 $969.00
View Old Accession Versions >>
OMu35271	XM_006504202.3	Mus musculus sortilin-related VPS10 domain containing receptor 2 (Sorcs2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Sorcs2 ( XM_030254926.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030110786.1 Mus musculus sortilin-related VPS10 domain containing receptor 2 (Sorcs2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu89049
Clone ID Related Accession (Same CDS sequence)	XM_030254926.1
Accession Version	XM_030254926.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2730bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	VPS10 domain-containing receptor SorCS2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTCCTCT TCCACCCGAA GGAGGAGGAC AAGGTGCTGG CCTACACCAA GGACAGCAAG 
CTGTATGTGT CATCGGACCT GGGAAAGAAG TGGACACTTC TGCAGGAACG GGTGACCAAG 
GACCACGTGT TCTGGGCTGT GTCTGGGGTG GATGACGACC CAAACTTGGT CCACGTGGAA 
GCTCAGGACC TCAGTGGAGG CTATCGGTAC TACACGTGTC TGATCTACAA CTGCTCAGCC 
CAGCCACACA TAGCACCCTT CTCCGGCCCC ATTGACCGCG GGTCCCTGAC CGTGCAGGAT 
GAGTACATCT TTTTGAAGGC AACATCAACA AACCGAACCA AGTACTATGT CTCCTATCGC 
CGAAGTGACT TTGTCCTGAT GAAGCTGCCC AAGTATGCCC TGCCCAAGGA CCTACAGATC 
ATCAGCACGG ATGAGCAGCA GGTGTTTGTG GCCGTACAGG AGTGGAACCA GGTAGACACC 
TACAACCTGT ACCAGTCAGA CCTGCGTGGG GTTCGCTATT CCCTGGTGCT GGAGAATGTG 
CGCAGCTCGA GGCAAGCCGA GGAGAACGTG GTCATCGACA TCCTTGAGGT CAGAGGGGTG 
AAGGGAGTCT TCTTGGCAAA CCAGAAAGTG GATGGCAAGG TGACCACAGT CATAACCTAC 
AACAAGGGCC GTGACTGGGA TTACCTGAGG CCACCCAGCA CCGACATGAA TGGGAAGCCC 
ACCAACTGCC AGCCGCCGGA CTGTTACCTG CACCTGCACT TGCGGTGGGC AGACAACCCC 
TATGTGTCAG GCACGGTACA CACCAAGGAC ACTGCCCCTG GTCTCATCAT GGGTGCAGGT 
AACCTGGGCT CACAGCTGGT GGAGTATAAA GAGGAGATGT ACATCACATC TGACTGCGGG 
CACACCTGGA GGCAGGTCTT TGAGGAAGAG CACCATGTGT TGTACCTGGA CCACGGTGGT 
GTCATTGCCG CCATCAAGGA CACCTCCATC CCCCTGAAGA TCCTCAAGTT CAGCGTGGAT 
GAGGGCCACA CGTGGAGCAC ACACAACTTC ACCAGCACCT CAGTGTTCGT GGATGGGTTG 
CTGAGCGAGC CAGGGGATGA GACGCTGGTC ATGACGGTCT TTGGTCACAT CAGCTTCCGC 
TCTGACTGGG AGCTGGTCAA GGTTGACTTC CGGCCCTCCT TCCCCCGGCA GTGTGGCGAG 
GATGACTACA GCTCCTGGGA CCTCACTGAC CTCCAGGGTG ATCACTGCAT CATGGGCCAA 
CAGAGAAGTT ACCGGAAGAG AAAGTCCACA TCCTGGTGTG TCAAGGGACG GAGCTTCACA 
TCAGCACTCA CGTCACGTGT GTGCAAGTGC CGGGACTCCG ACTTCCTCTG TGACTACGGG 
TTTGAGCGCT CATCTTCCTC GGAGTCCACT GCCAACAAGT GCTCTGCCAA CTTCTGGTTC 
AACCCTTTGT CTCCTCCTGA AGACTGTGTC TTGGGTCAGA CTTACACTAG TAGCCTTGGG 
TACCGGAAGG TGGTGTCCAA TGTGTGTGAA GGTGGTGTGG ACCTGCAGCA GAGCCCAGTG 
CAGCTGCAGT GCCCCCTCCA GGCACCCCGG GGCCTGCAGG TGAGCATCCG AGGAGAGGCA 
GTGGCCGTGC GGCCTAGAGA AGATGTGCTG TTTGTGGTGC GACAGGAACA GGGTGATGTC 
CTGACCACTA AATATCAGGT GGATCTTGGG GATGGCTTCA AGGCCATGTA CGTGAACCTC 
ACTCTGACAG GCGAGCCCAT TCGACATCAC TATGAGAGTC CTGGCATCTA CCGAGTGTCC 
GTCAGGGCTG AGAACATGGC AGGCCATGAT GAGGCTGTGC TCTTTGTCCA GGTCAACTCT 
CCCCTGCAGG CCCTCTACCT CGAGGTAGTT CCTGTCATTG GCGTCAACCA GGAGGTGAAC 
CTCACAGCCG TGCTGTTACC CCTGAATCCC AACCTCACTG TCTTCTACTG GTGGATCGGC 
CACAGCTTGC AGCCTCTGCT TTCCTTGGAC AACTCGGTGA CAACAAAGTT TACGGACGCT 
GGGGATGTGC GTGTGACAGT GCAAGCTGCC TGCGGGAACT CAGTGCTTCA GGACTCCAGG 
CTCGTCCGTG TGCTCGATCA GTTCCAGGTG GTGCCTCTGC GGTTCTCCAG GGAGCTGGAC 
ACCTTTAACC CCAACACTCC TGAATGGAGG GAAGATGTGG GACTGGTGGT CACCCGACTG 
CTCTCCAAGG AGACCAGCAT CCCAGAGGAG CTGCTTGTGA CTGTGGTAAA GCCAGGGCTG 
CCCACCATAG CCGACTTGTA TGTGCTTCTG CCTCTGCCAA GGCCCACAAG GAAGAGGAGC 
CTCACAAGTG ACAAGAGACT GGCAGCCGTG CAGCAGGCGC TGAACTCTCA TAGAATCAGC 
TTCATCCTTC GAGGAGGGCT TCGTATCCTG GTGGAGCTGA GGGACACAGA CACAGGTCCT 
CAGAGGCCAG GTGGCAGTGG TGGCTACTGG GCCGTGGTGG TCCTCTTTGT CATTGGGCTC 
TTTGCAGTAG GAGCATTCAT CCTCTACAAG TTCAAAAGCA GGAAACGTCC AGGCAGGACA 
GTGTACGCCC AGATGCACAA TGAGAAGGAA CAGGAGATGA CAAGTCCCGT GAGTCACAGT 
GAGGATGCCC AGAGCACCAT GCAGGGCAAC CACTCAGGGG TGGTCCTGAG CATCAACTCT 
CGTGAGATGC ATAGCTACCT GGTGGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030110786.1
CDS	339..3068
Translation	MLLFHPKEEDKVLAYTKDSKLYVSSDLGKKWTLLQERVTKDHVFWAVSGVDDDPNLVHVEAQDLSGGYRYYTCLIYNCSAQPHIAPFSGPIDRGSLTVQDEYIFLKATSTNRTKYYVSYRRSDFVLMKLPKYALPKDLQIISTDEQQVFVAVQEWNQVDTYNLYQSDLRGVRYSLVLENVRSSRQAEENVVIDILEVRGVKGVFLANQKVDGKVTTVITYNKGRDWDYLRPPSTDMNGKPTNCQPPDCYLHLHLRWADNPYVSGTVHTKDTAPGLIMGAGNLGSQLVEYKEEMYITSDCGHTWRQVFEEEHHVLYLDHGGVIAAIKDTSIPLKILKFSVDEGHTWSTHNFTSTSVFVDGLLSEPGDETLVMTVFGHISFRSDWELVKVDFRPSFPRQCGEDDYSSWDLTDLQGDHCIMGQQRSYRKRKSTSWCVKGRSFTSALTSRVCKCRDSDFLCDYGFERSSSSESTANKCSANFWFNPLSPPEDCVLGQTYTSSLGYRKVVSNVCEGGVDLQQSPVQLQCPLQAPRGLQVSIRGEAVAVRPREDVLFVVRQEQGDVLTTKYQVDLGDGFKAMYVNLTLTGEPIRHHYESPGIYRVSVRAENMAGHDEAVLFVQVNSPLQALYLEVVPVIGVNQEVNLTAVLLPLNPNLTVFYWWIGHSLQPLLSLDNSVTTKFTDAGDVRVTVQAACGNSVLQDSRLVRVLDQFQVVPLRFSRELDTFNPNTPEWREDVGLVVTRLLSKETSIPEELLVTVVKPGLPTIADLYVLLPLPRPTRKRSLTSDKRLAAVQQALNSHRISFILRGGLRILVELRDTDTGPQRPGGSGGYWAVVVLFVIGLFAVGAFILYKFKSRKRPGRTVYAQMHNEKEQEMTSPVSHSEDAQSTMQGNHSGVVLSINSREMHSYLVG

Target ORF information:

RefSeq Version	XM_030254926.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus sortilin-related VPS10 domain containing receptor 2 (Sorcs2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030254926.1

ORF Insert Sequence:

ATGCTCCTCT TCCACCCGAA GGAGGAGGAC AAGGTGCTGG CCTACACCAA GGACAGCAAG 
CTGTATGTGT CATCGGACCT GGGAAAGAAG TGGACACTTC TGCAGGAACG GGTGACCAAG 
GACCACGTGT TCTGGGCTGT GTCTGGGGTG GATGACGACC CAAACTTGGT CCACGTGGAA 
GCTCAGGACC TCAGTGGAGG CTATCGGTAC TACACGTGTC TGATCTACAA CTGCTCAGCC 
CAGCCACACA TAGCACCCTT CTCCGGCCCC ATTGACCGCG GGTCCCTGAC CGTGCAGGAT 
GAGTACATCT TTTTGAAGGC AACATCAACA AACCGAACCA AGTACTATGT CTCCTATCGC 
CGAAGTGACT TTGTCCTGAT GAAGCTGCCC AAGTATGCCC TGCCCAAGGA CCTACAGATC 
ATCAGCACGG ATGAGCAGCA GGTGTTTGTG GCCGTACAGG AGTGGAACCA GGTAGACACC 
TACAACCTGT ACCAGTCAGA CCTGCGTGGG GTTCGCTATT CCCTGGTGCT GGAGAATGTG 
CGCAGCTCGA GGCAAGCCGA GGAGAACGTG GTCATCGACA TCCTTGAGGT CAGAGGGGTG 
AAGGGAGTCT TCTTGGCAAA CCAGAAAGTG GATGGCAAGG TGACCACAGT CATAACCTAC 
AACAAGGGCC GTGACTGGGA TTACCTGAGG CCACCCAGCA CCGACATGAA TGGGAAGCCC 
ACCAACTGCC AGCCGCCGGA CTGTTACCTG CACCTGCACT TGCGGTGGGC AGACAACCCC 
TATGTGTCAG GCACGGTACA CACCAAGGAC ACTGCCCCTG GTCTCATCAT GGGTGCAGGT 
AACCTGGGCT CACAGCTGGT GGAGTATAAA GAGGAGATGT ACATCACATC TGACTGCGGG 
CACACCTGGA GGCAGGTCTT TGAGGAAGAG CACCATGTGT TGTACCTGGA CCACGGTGGT 
GTCATTGCCG CCATCAAGGA CACCTCCATC CCCCTGAAGA TCCTCAAGTT CAGCGTGGAT 
GAGGGCCACA CGTGGAGCAC ACACAACTTC ACCAGCACCT CAGTGTTCGT GGATGGGTTG 
CTGAGCGAGC CAGGGGATGA GACGCTGGTC ATGACGGTCT TTGGTCACAT CAGCTTCCGC 
TCTGACTGGG AGCTGGTCAA GGTTGACTTC CGGCCCTCCT TCCCCCGGCA GTGTGGCGAG 
GATGACTACA GCTCCTGGGA CCTCACTGAC CTCCAGGGTG ATCACTGCAT CATGGGCCAA 
CAGAGAAGTT ACCGGAAGAG AAAGTCCACA TCCTGGTGTG TCAAGGGACG GAGCTTCACA 
TCAGCACTCA CGTCACGTGT GTGCAAGTGC CGGGACTCCG ACTTCCTCTG TGACTACGGG 
TTTGAGCGCT CATCTTCCTC GGAGTCCACT GCCAACAAGT GCTCTGCCAA CTTCTGGTTC 
AACCCTTTGT CTCCTCCTGA AGACTGTGTC TTGGGTCAGA CTTACACTAG TAGCCTTGGG 
TACCGGAAGG TGGTGTCCAA TGTGTGTGAA GGTGGTGTGG ACCTGCAGCA GAGCCCAGTG 
CAGCTGCAGT GCCCCCTCCA GGCACCCCGG GGCCTGCAGG TGAGCATCCG AGGAGAGGCA 
GTGGCCGTGC GGCCTAGAGA AGATGTGCTG TTTGTGGTGC GACAGGAACA GGGTGATGTC 
CTGACCACTA AATATCAGGT GGATCTTGGG GATGGCTTCA AGGCCATGTA CGTGAACCTC 
ACTCTGACAG GCGAGCCCAT TCGACATCAC TATGAGAGTC CTGGCATCTA CCGAGTGTCC 
GTCAGGGCTG AGAACATGGC AGGCCATGAT GAGGCTGTGC TCTTTGTCCA GGTCAACTCT 
CCCCTGCAGG CCCTCTACCT CGAGGTAGTT CCTGTCATTG GCGTCAACCA GGAGGTGAAC 
CTCACAGCCG TGCTGTTACC CCTGAATCCC AACCTCACTG TCTTCTACTG GTGGATCGGC 
CACAGCTTGC AGCCTCTGCT TTCCTTGGAC AACTCGGTGA CAACAAAGTT TACGGACGCT 
GGGGATGTGC GTGTGACAGT GCAAGCTGCC TGCGGGAACT CAGTGCTTCA GGACTCCAGG 
CTCGTCCGTG TGCTCGATCA GTTCCAGGTG GTGCCTCTGC GGTTCTCCAG GGAGCTGGAC 
ACCTTTAACC CCAACACTCC TGAATGGAGG GAAGATGTGG GACTGGTGGT CACCCGACTG 
CTCTCCAAGG AGACCAGCAT CCCAGAGGAG CTGCTTGTGA CTGTGGTAAA GCCAGGGCTG 
CCCACCATAG CCGACTTGTA TGTGCTTCTG CCTCTGCCAA GGCCCACAAG GAAGAGGAGC 
CTCACAAGTG ACAAGAGACT GGCAGCCGTG CAGCAGGCGC TGAACTCTCA TAGAATCAGC 
TTCATCCTTC GAGGAGGGCT TCGTATCCTG GTGGAGCTGA GGGACACAGA CACAGGTCCT 
CAGAGGCCAG GTGGCAGTGG TGGCTACTGG GCCGTGGTGG TCCTCTTTGT CATTGGGCTC 
TTTGCAGTAG GAGCATTCAT CCTCTACAAG TTCAAAAGCA GGAAACGTCC AGGCAGGACA 
GTGTACGCCC AGATGCACAA TGAGAAGGAA CAGGAGATGA CAAGTCCCGT GAGTCACAGT 
GAGGATGCCC AGAGCACCAT GCAGGGCAAC CACTCAGGGG TGGTCCTGAG CATCAACTCT 
CGTGAGATGC ATAGCTACCT GGTGGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Sorcs2 ( XM_006504202.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006504265.1 Mus musculus sortilin-related VPS10 domain containing receptor 2 (Sorcs2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu35271
Clone ID Related Accession (Same CDS sequence)	XM_006504202.3 , XM_006504202.4
Accession Version	XM_006504202.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3483bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	VPS10 domain-containing receptor SorCS2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006504202.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGCACC GGGGACCCCC GAGCGCCCCG AAGCGTCCTG GCCCTACTGC GCCGGACCGG 
AGCTTTCAGG CTCTGCTGCC GCCGTGCTGG CCACGTTCGT GGCCGCTGCT GCTGCTGCTG 
CTGGTGCTGG TGGCTGCCTG CGGAGCGATG GGGCGCTCCC CCCAGCCCGG GCGCCAGGGT 
CCCGGTGTGC AGATCACTAG GCTGCTGCCC GCGGGACGCA CGGAGTCCGG CGATCGCAAA 
GATCCACAGG CACGAGAATC AGAACCCAGC GTCCCGGGTC TCGGTCCGGG TTCTGCTTCG 
GGTCCCAGCA CCGATGGCGC CCCAGCTCCG GGCAAGGGGC GCAGGGCTCG GGCGGTGCCG 
GTGGCCGGTG CGGCTTCGGC TTCGCGCGCA CAGGTCTCGC TCATCAGCAC GTCGTTCGTG 
CTCAAGGGAG ACGCGACGCA CAACCAGGCG ATGGTACACT GGACAGGAGA GAACAGCAGC 
GTCATCTTGA TCCTGACAAA GTACTACCAT GCAGACATGG GCAAGGTTCT GGAAAGTTCT 
CTGTGGAGGT CCTCAGATTT TGGGACAACC TACACCAAGC TTACTCTCCA GCCTGGTGTC 
ACCACTGTCA TTGACAACTT CTATATCTGC CCAGCTAACA AAAGGAAGAT CATCCTGGTG 
AGCTCATCCC TCGGTGACCG GGAACAGAGC CTCTTCCTCA GCACTGATGA GGGCGCCACG 
TTCCAGAAGT ATCCTGTCCC CTTCCTTGTG GAGATGCTCC TCTTCCACCC GAAGGAGGAG 
GACAAGGTGC TGGCCTACAC CAAGGACAGC AAGCTGTATG TGTCATCGGA CCTGGGAAAG 
AAGTGGACAC TTCTGCAGGA ACGGGTGACC AAGGACCACG TGTTCTGGGC TGTGTCTGGG 
GTGGATGACG ACCCAAACTT GGTCCACGTG GAAGCTCAGG ACCTCAGTGG AGGCTATCGG 
TACTACACGT GTCTGATCTA CAACTGCTCA GCCCAGCCAC ACATAGCACC CTTCTCCGGC 
CCCATTGACC GCGGGTCCCT GACCGTGCAG GATGAGTACA TCTTTTTGAA GGCAACATCA 
ACAAACCGAA CCAAGTACTA TGTCTCCTAT CGCCGAAGTG ACTTTGTCCT GATGAAGCTG 
CCCAAGTATG CCCTGCCCAA GGACCTACAG ATCATCAGCA CGGATGAGCA GCAGGTGTTT 
GTGGCCGTAC AGGAGTGGAA CCAGGTAGAC ACCTACAACC TGTACCAGTC AGACCTGCGT 
GGGGTTCGCT ATTCCCTGGT GCTGGAGAAT GTGCGCAGCT CGAGGCAAGC CGAGGAGAAC 
GTGGTCATCG ACATCCTTGA GGTCAGAGGG GTGAAGGGAG TCTTCTTGGC AAACCAGAAA 
GTGGATGGCA AGGTGACCAC AGTCATAACC TACAACAAGG GCCGTGACTG GGATTACCTG 
AGGCCACCCA GCACCGACAT GAATGGGAAG CCCACCAACT GCCAGCCGCC GGACTGTTAC 
CTGCACCTGC ACTTGCGGTG GGCAGACAAC CCCTATGTGT CAGGCACGGT ACACACCAAG 
GACACTGCCC CTGGTCTCAT CATGGGTGCA GGTAACCTGG GCTCACAGCT GGTGGAGTAT 
AAAGAGGAGA TGTACATCAC ATCTGACTGC GGGCACACCT GGAGGCAGGT CTTTGAGGAA 
GAGCACCATG TGTTGTACCT GGACCACGGT GGTGTCATTG CCGCCATCAA GGACACCTCC 
ATCCCCCTGA AGATCCTCAA GTTCAGCGTG GATGAGGGCC ACACGTGGAG CACACACAAC 
TTCACCAGCA CCTCAGTGTT CGTGGATGGG TTGCTGAGCG AGCCAGGGGA TGAGACGCTG 
GTCATGACGG TCTTTGGTCA CATCAGCTTC CGCTCTGACT GGGAGCTGGT CAAGGTTGAC 
TTCCGGCCCT CCTTCCCCCG GCAGTGTGGC GAGGATGACT ACAGCTCCTG GGACCTCACT 
GACCTCCAGG GTGATCACTG CATCATGGGC CAACAGAGAA GTTACCGGAA GAGAAAGTCC 
ACATCCTGGT GTGTCAAGGG ACGGAGCTTC ACATCAGCAC TCACGTCACG TGTGTGCAAG 
TGCCGGGACT CCGACTTCCT CTGTGACTAC GGGTTTGAGC GCTCATCTTC CTCGGAGTCC 
ACTGCCAACA AGTGCTCTGC CAACTTCTGG TTCAACCCTT TGTCTCCTCC TGAAGACTGT 
GTCTTGGGTC AGACTTACAC TAGTAGCCTT GGGTACCGGA AGGTGGTGTC CAATGTGTGT 
GAAGGTGGTG TGGACCTGCA GCAGAGCCCA GTGCAGCTGC AGTGCCCCCT CCAGGCACCC 
CGGGGCCTGC AGGTGAGCAT CCGAGGAGAG GCAGTGGCCG TGCGGCCTAG AGAAGATGTG 
CTGTTTGTGG TGCGACAGGA ACAGGGTGAT GTCCTGACCA CTAAATATCA GGTGGATCTT 
GGGGATGGCT TCAAGGCCAT GTACGTGAAC CTCACTCTGA CAGGCGAGCC CATTCGACAT 
CACTATGAGA GTCCTGGCAT CTACCGAGTG TCCGTCAGGG CTGAGAACAT GGCAGGCCAT 
GATGAGGCTG TGCTCTTTGT CCAGGTCAAC TCTCCCCTGC AGGCCCTCTA CCTCGAGGTA 
GTTCCTGTCA TTGGCGTCAA CCAGGAGGTG AACCTCACAG CCGTGCTGTT ACCCCTGAAT 
CCCAACCTCA CTGTCTTCTA CTGGTGGATC GGCCACAGCT TGCAGCCTCT GCTTTCCTTG 
GACAACTCGG TGACAACAAA GTTTACGGAC GCTGGGGATG TGCGTGTGAC AGTGCAAGCT 
GCCTGCGGGA ACTCAGTGCT TCAGGACTCC AGGCTCGTCC GTGTGCTCGA TCAGTTCCAG 
GTGGTGCCTC TGCGGTTCTC CAGGGAGCTG GACACCTTTA ACCCCAACAC TCCTGAATGG 
AGGGAAGATG TGGGACTGGT GGTCACCCGA CTGCTCTCCA AGGAGACCAG CATCCCAGAG 
GAGCTGCTTG TGACTGTGGT AAAGCCAGGG CTGCCCACCA TAGCCGACTT GTATGTGCTT 
CTGCCTCTGC CAAGGCCCAC AAGGAAGAGG AGCCTCACAA GTGACAAGAG ACTGGCAGCC 
GTGCAGCAGG CGCTGAACTC TCATAGAATC AGCTTCATCC TTCGAGGAGG GCTTCGTATC 
CTGGTGGAGC TGAGGGACAC AGACACAGGT CCTCAGAGGC CAGGTGGCAG TGGTGGCTAC 
TGGGCCGTGG TGGTCCTCTT TGTCATTGGG CTCTTTGCAG TAGGAGCATT CATCCTCTAC 
AAGTTCAAAA GCAGGAAACG TCCAGGCAGG ACAGTGTACG CCCAGATGCA CAATGAGAAG 
GAACAGGAGA TGACAAGTCC CGTGAGTCAC AGTGAGGATG CCCAGAGCAC CATGCAGGGC 
AACCACTCAG GGGTGGTCCT GAGCATCAAC TCTCGTGAGA TGCATAGCTA CCTGGTGGGC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006504265.1
CDS	153..3635
Translation	MAHRGPPSAPKRPGPTAPDRSFQALLPPCWPRSWPLLLLLLVLVAACGAMGRSPQPGRQGPGVQITRLLPAGRTESGDRKDPQARESEPSVPGLGPGSASGPSTDGAPAPGKGRRARAVPVAGAASASRAQVSLISTSFVLKGDATHNQAMVHWTGENSSVILILTKYYHADMGKVLESSLWRSSDFGTTYTKLTLQPGVTTVIDNFYICPANKRKIILVSSSLGDREQSLFLSTDEGATFQKYPVPFLVEMLLFHPKEEDKVLAYTKDSKLYVSSDLGKKWTLLQERVTKDHVFWAVSGVDDDPNLVHVEAQDLSGGYRYYTCLIYNCSAQPHIAPFSGPIDRGSLTVQDEYIFLKATSTNRTKYYVSYRRSDFVLMKLPKYALPKDLQIISTDEQQVFVAVQEWNQVDTYNLYQSDLRGVRYSLVLENVRSSRQAEENVVIDILEVRGVKGVFLANQKVDGKVTTVITYNKGRDWDYLRPPSTDMNGKPTNCQPPDCYLHLHLRWADNPYVSGTVHTKDTAPGLIMGAGNLGSQLVEYKEEMYITSDCGHTWRQVFEEEHHVLYLDHGGVIAAIKDTSIPLKILKFSVDEGHTWSTHNFTSTSVFVDGLLSEPGDETLVMTVFGHISFRSDWELVKVDFRPSFPRQCGEDDYSSWDLTDLQGDHCIMGQQRSYRKRKSTSWCVKGRSFTSALTSRVCKCRDSDFLCDYGFERSSSSESTANKCSANFWFNPLSPPEDCVLGQTYTSSLGYRKVVSNVCEGGVDLQQSPVQLQCPLQAPRGLQVSIRGEAVAVRPREDVLFVVRQEQGDVLTTKYQVDLGDGFKAMYVNLTLTGEPIRHHYESPGIYRVSVRAENMAGHDEAVLFVQVNSPLQALYLEVVPVIGVNQEVNLTAVLLPLNPNLTVFYWWIGHSLQPLLSLDNSVTTKFTDAGDVRVTVQAACGNSVLQDSRLVRVLDQFQVVPLRFSRELDTFNPNTPEWREDVGLVVTRLLSKETSIPEELLVTVVKPGLPTIADLYVLLPLPRPTRKRSLTSDKRLAAVQQALNSHRISFILRGGLRILVELRDTDTGPQRPGGSGGYWAVVVLFVIGLFAVGAFILYKFKSRKRPGRTVYAQMHNEKEQEMTSPVSHSEDAQSTMQGNHSGVVLSINSREMHSYLVG

Target ORF information:

RefSeq Version	XM_006504202.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus sortilin-related VPS10 domain containing receptor 2 (Sorcs2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006504202.4

ORF Insert Sequence:

ATGGCGCACC GGGGACCCCC GAGCGCCCCG AAGCGTCCTG GCCCTACTGC GCCGGACCGG 
AGCTTTCAGG CTCTGCTGCC GCCGTGCTGG CCACGTTCGT GGCCGCTGCT GCTGCTGCTG 
CTGGTGCTGG TGGCTGCCTG CGGAGCGATG GGGCGCTCCC CCCAGCCCGG GCGCCAGGGT 
CCCGGTGTGC AGATCACTAG GCTGCTGCCC GCGGGACGCA CGGAGTCCGG CGATCGCAAA 
GATCCACAGG CACGAGAATC AGAACCCAGC GTCCCGGGTC TCGGTCCGGG TTCTGCTTCG 
GGTCCCAGCA CCGATGGCGC CCCAGCTCCG GGCAAGGGGC GCAGGGCTCG GGCGGTGCCG 
GTGGCCGGTG CGGCTTCGGC TTCGCGCGCA CAGGTCTCGC TCATCAGCAC GTCGTTCGTG 
CTCAAGGGAG ACGCGACGCA CAACCAGGCG ATGGTACACT GGACAGGAGA GAACAGCAGC 
GTCATCTTGA TCCTGACAAA GTACTACCAT GCAGACATGG GCAAGGTTCT GGAAAGTTCT 
CTGTGGAGGT CCTCAGATTT TGGGACAACC TACACCAAGC TTACTCTCCA GCCTGGTGTC 
ACCACTGTCA TTGACAACTT CTATATCTGC CCAGCTAACA AAAGGAAGAT CATCCTGGTG 
AGCTCATCCC TCGGTGACCG GGAACAGAGC CTCTTCCTCA GCACTGATGA GGGCGCCACG 
TTCCAGAAGT ATCCTGTCCC CTTCCTTGTG GAGATGCTCC TCTTCCACCC GAAGGAGGAG 
GACAAGGTGC TGGCCTACAC CAAGGACAGC AAGCTGTATG TGTCATCGGA CCTGGGAAAG 
AAGTGGACAC TTCTGCAGGA ACGGGTGACC AAGGACCACG TGTTCTGGGC TGTGTCTGGG 
GTGGATGACG ACCCAAACTT GGTCCACGTG GAAGCTCAGG ACCTCAGTGG AGGCTATCGG 
TACTACACGT GTCTGATCTA CAACTGCTCA GCCCAGCCAC ACATAGCACC CTTCTCCGGC 
CCCATTGACC GCGGGTCCCT GACCGTGCAG GATGAGTACA TCTTTTTGAA GGCAACATCA 
ACAAACCGAA CCAAGTACTA TGTCTCCTAT CGCCGAAGTG ACTTTGTCCT GATGAAGCTG 
CCCAAGTATG CCCTGCCCAA GGACCTACAG ATCATCAGCA CGGATGAGCA GCAGGTGTTT 
GTGGCCGTAC AGGAGTGGAA CCAGGTAGAC ACCTACAACC TGTACCAGTC AGACCTGCGT 
GGGGTTCGCT ATTCCCTGGT GCTGGAGAAT GTGCGCAGCT CGAGGCAAGC CGAGGAGAAC 
GTGGTCATCG ACATCCTTGA GGTCAGAGGG GTGAAGGGAG TCTTCTTGGC AAACCAGAAA 
GTGGATGGCA AGGTGACCAC AGTCATAACC TACAACAAGG GCCGTGACTG GGATTACCTG 
AGGCCACCCA GCACCGACAT GAATGGGAAG CCCACCAACT GCCAGCCGCC GGACTGTTAC 
CTGCACCTGC ACTTGCGGTG GGCAGACAAC CCCTATGTGT CAGGCACGGT ACACACCAAG 
GACACTGCCC CTGGTCTCAT CATGGGTGCA GGTAACCTGG GCTCACAGCT GGTGGAGTAT 
AAAGAGGAGA TGTACATCAC ATCTGACTGC GGGCACACCT GGAGGCAGGT CTTTGAGGAA 
GAGCACCATG TGTTGTACCT GGACCACGGT GGTGTCATTG CCGCCATCAA GGACACCTCC 
ATCCCCCTGA AGATCCTCAA GTTCAGCGTG GATGAGGGCC ACACGTGGAG CACACACAAC 
TTCACCAGCA CCTCAGTGTT CGTGGATGGG TTGCTGAGCG AGCCAGGGGA TGAGACGCTG 
GTCATGACGG TCTTTGGTCA CATCAGCTTC CGCTCTGACT GGGAGCTGGT CAAGGTTGAC 
TTCCGGCCCT CCTTCCCCCG GCAGTGTGGC GAGGATGACT ACAGCTCCTG GGACCTCACT 
GACCTCCAGG GTGATCACTG CATCATGGGC CAACAGAGAA GTTACCGGAA GAGAAAGTCC 
ACATCCTGGT GTGTCAAGGG ACGGAGCTTC ACATCAGCAC TCACGTCACG TGTGTGCAAG 
TGCCGGGACT CCGACTTCCT CTGTGACTAC GGGTTTGAGC GCTCATCTTC CTCGGAGTCC 
ACTGCCAACA AGTGCTCTGC CAACTTCTGG TTCAACCCTT TGTCTCCTCC TGAAGACTGT 
GTCTTGGGTC AGACTTACAC TAGTAGCCTT GGGTACCGGA AGGTGGTGTC CAATGTGTGT 
GAAGGTGGTG TGGACCTGCA GCAGAGCCCA GTGCAGCTGC AGTGCCCCCT CCAGGCACCC 
CGGGGCCTGC AGGTGAGCAT CCGAGGAGAG GCAGTGGCCG TGCGGCCTAG AGAAGATGTG 
CTGTTTGTGG TGCGACAGGA ACAGGGTGAT GTCCTGACCA CTAAATATCA GGTGGATCTT 
GGGGATGGCT TCAAGGCCAT GTACGTGAAC CTCACTCTGA CAGGCGAGCC CATTCGACAT 
CACTATGAGA GTCCTGGCAT CTACCGAGTG TCCGTCAGGG CTGAGAACAT GGCAGGCCAT 
GATGAGGCTG TGCTCTTTGT CCAGGTCAAC TCTCCCCTGC AGGCCCTCTA CCTCGAGGTA 
GTTCCTGTCA TTGGCGTCAA CCAGGAGGTG AACCTCACAG CCGTGCTGTT ACCCCTGAAT 
CCCAACCTCA CTGTCTTCTA CTGGTGGATC GGCCACAGCT TGCAGCCTCT GCTTTCCTTG 
GACAACTCGG TGACAACAAA GTTTACGGAC GCTGGGGATG TGCGTGTGAC AGTGCAAGCT 
GCCTGCGGGA ACTCAGTGCT TCAGGACTCC AGGCTCGTCC GTGTGCTCGA TCAGTTCCAG 
GTGGTGCCTC TGCGGTTCTC CAGGGAGCTG GACACCTTTA ACCCCAACAC TCCTGAATGG 
AGGGAAGATG TGGGACTGGT GGTCACCCGA CTGCTCTCCA AGGAGACCAG CATCCCAGAG 
GAGCTGCTTG TGACTGTGGT AAAGCCAGGG CTGCCCACCA TAGCCGACTT GTATGTGCTT 
CTGCCTCTGC CAAGGCCCAC AAGGAAGAGG AGCCTCACAA GTGACAAGAG ACTGGCAGCC 
GTGCAGCAGG CGCTGAACTC TCATAGAATC AGCTTCATCC TTCGAGGAGG GCTTCGTATC 
CTGGTGGAGC TGAGGGACAC AGACACAGGT CCTCAGAGGC CAGGTGGCAG TGGTGGCTAC 
TGGGCCGTGG TGGTCCTCTT TGTCATTGGG CTCTTTGCAG TAGGAGCATT CATCCTCTAC 
AAGTTCAAAA GCAGGAAACG TCCAGGCAGG ACAGTGTACG CCCAGATGCA CAATGAGAAG 
GAACAGGAGA TGACAAGTCC CGTGAGTCAC AGTGAGGATG CCCAGAGCAC CATGCAGGGC 
AACCACTCAG GGGTGGTCCT GAGCATCAAC TCTCGTGAGA TGCATAGCTA CCTGGTGGGC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Sorcs2 ( NM_030889.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_112151.2 Mus musculus sortilin-related VPS10 domain containing receptor 2 (Sorcs2), mRNA.

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CloneID	OMu08478
Clone ID Related Accession (Same CDS sequence)	NM_030889.2
Accession Version	NM_030889.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3480bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-03
Organism	Mus musculus(house mouse)
Product	VPS10 domain-containing receptor SorCS2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK047881.1, AK053853.1, AY004316.1, CO428928.1, CV784176.1 and AC127275.4. On Jan 31, 2007 this sequence version replaced NM_030889.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB093294.1, AY004316.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END##

ATGGCGCACC GGGGACCCCC GAGCGCCCCG AAGCGTCCTG GCCCTACTGC GCCGGACCGG 
AGCTTTCAGG CTCTGCTGCC GCCGTGCTGG CCACGTTCGT GGCCGCTGCT GCTGCTGCTG 
CTGGTGCTGG TGGCTGCCTG CGGAGCGATG GGGCGCTCCC CCCAGCCCGG GCGCCAGGGT 
CCCGGTGTGC AGATCACTAG GCTGCTGCCC GCGGGACGCA CGGAGTCCGG CGATCGCAAA 
GATCCACAGG CACGAGAATC AGAACCCAGC GTCCCGGGTC TCGGTCCGGG TTCTGCTTCG 
GGTCCCAGCA CCGATGGCGC CCCAGCTCCG GGCAAGGGGC GCAGGGCTCG GGCGGTGCCG 
GTGGCCGGTG CGGCTTCGGC TTCGCGCGCA CAGGTCTCGC TCATCAGCAC GTCGTTCGTG 
CTCAAGGGAG ACGCGACGCA CAACCAGGCG ATGGTACACT GGACAGGAGA GAACAGCAGC 
GTCATCTTGA TCCTGACAAA GTACTACCAT GCAGACATGG GCAAGGTTCT GGAAAGTTCT 
CTGTGGAGGT CCTCAGATTT TGGGACAACC TACACCAAGC TTACTCTCCA GCCTGGTGTC 
ACCACTGTCA TTGACAACTT CTATATCTGC CCAGCTAACA AAAGGAAGAT CATCCTGGTG 
AGCTCATCCC TCGGTGACCG GGAACAGAGC CTCTTCCTCA GCACTGATGA GGGCGCCACG 
TTCCAGAAGT ATCCTGTCCC CTTCCTTGTG GAGATGCTCC TCTTCCACCC GAAGGAGGAG 
GACAAGGTGC TGGCCTACAC CAAGGACAGC AAGCTGTATG TGTCATCGGA CCTGGGAAAG 
AAGTGGACAC TTCTGCAGGA ACGGGTGACC AAGGACCACG TGTTCTGGGC TGTGTCTGGG 
GTGGATGACG ACCCAAACTT GGTCCACGTG GAAGCTCAGG ACCTCAGTGG AGGCTATCGG 
TACTACACGT GTCTGATCTA CAACTGCTCA GCCCAGCCAC ACATAGCACC CTTCTCCGGC 
CCCATTGACC GCGGGTCCCT GACCGTGCAG GATGAGTACA TCTTTTTGAA GGCAACATCA 
ACAAACCGAA CCAAGTACTA TGTCTCCTAT CGCCGAAGTG ACTTTGTCCT GATGAAGCTG 
CCCAAGTATG CCCTGCCCAA GGACCTACAG ATCATCAGCA CGGATGAGCA GCAGGTGTTT 
GTGGCCGTAC AGGAGTGGAA CCAGGTAGAC ACCTACAACC TGTACCAGTC AGACCTGCGT 
GGGGTTCGCT ATTCCCTGGT GCTGGAGAAT GTGCGCAGCT CGAGGCAAGC CGAGGAGAAC 
GTGGTCATCG ACATCCTTGA GGTCAGAGGG GTGAAGGGAG TCTTCTTGGC AAACCAGAAA 
GTGGATGGCA AGGTGACCAC AGTCATAACC TACAACAAGG GCCGTGACTG GGATTACCTG 
AGGCCACCCA GCACCGACAT GAATGGGAAG CCCACCAACT GCCAGCCGCC GGACTGTTAC 
CTGCACCTGC ACTTGCGGTG GGCAGACAAC CCCTATGTGT CAGGCACGGT ACACACCAAG 
GACACTGCCC CTGGTCTCAT CATGGGTGCA GGTAACCTGG GCTCACAGCT GGTGGAGTAT 
AAAGAGGAGA TGTACATCAC ATCTGACTGC GGGCACACCT GGAGGCAGGT CTTTGAGGAA 
GAGCACCATG TGTTGTACCT GGACCACGGT GGTGTCATTG CCGCCATCAA GGACACCTCC 
ATCCCCCTGA AGATCCTCAA GTTCAGCGTG GATGAGGGCC ACACGTGGAG CACACACAAC 
TTCACCAGCA CCTCAGTGTT CGTGGATGGG TTGCTGAGCG AGCCAGGGGA TGAGACGCTG 
GTCATGACGG TCTTTGGTCA CATCAGCTTC CGCTCTGACT GGGAGCTGGT CAAGGTTGAC 
TTCCGGCCCT CCTTCCCCCG GCAGTGTGGC GAGGATGACT ACAGCTCCTG GGACCTCACT 
GACCTCCAGG GTGATCACTG CATCATGGGC CAACAGAGAA GTTACCGGAA GAGAAAGTCC 
ACATCCTGGT GTGTCAAGGG ACGGAGCTTC ACATCAGCAC TCACGTCACG TGTGTGCAAG 
TGCCGGGACT CCGACTTCCT CTGTGACTAC GGGTTTGAGC GCTCATCTTC CTCGGAGTCC 
ACTGCCAACA AGTGCTCTGC CAACTTCTGG TTCAACCCTT TGTCTCCTCC TGAAGACTGT 
GTCTTGGGTC AGACTTACAC TAGTAGCCTT GGGTACCGGA AGGTGGTGTC CAATGTGTGT 
GAAGGTGGTG TGGACCTGCA GCAGAGCCCA GTGCAGCTGC AGTGCCCCCT CCAGGCACCC 
CGGGGCCTGC AGGTGAGCAT CCGAGGAGAG GCAGTGGCCG TGCGGCCTAG AGAAGATGTG 
CTGTTTGTGG TGCGACAGGA ACAGGGTGAT GTCCTGACCA CTAAATATCA GGTGGATCTT 
GGGGATGGCT TCAAGGCCAT GTACGTGAAC CTCACTCTGA CAGGCGAGCC CATTCGACAT 
CACTATGAGA GTCCTGGCAT CTACCGAGTG TCCGTCAGGG CTGAGAACAT GGCAGGCCAT 
GATGAGGCTG TGCTCTTTGT CCAGGTCAAC TCTCCCCTGC AGGCCCTCTA CCTCGAGGTA 
GTTCCTGTCA TTGGCGTCAA CCAGGAGGTG AACCTCACAG CCGTGCTGTT ACCCCTGAAT 
CCCAACCTCA CTGTCTTCTA CTGGTGGATC GGCCACAGCT TGCAGCCTCT GCTTTCCTTG 
GACAACTCGG TGACAACAAA GTTTACGGAC GCTGGGGATG TGCGTGTGAC AGTGCAAGCT 
GCCTGCGGGA ACTCAGTGCT TCAGGACTCC AGGCTCGTCC GTGTGCTCGA TCAGTTCCAG 
GTGGTGCCTC TGCGGTTCTC CAGGGAGCTG GACACCTTTA ACCCCAACAC TCCTGAATGG 
AGGGAAGATG TGGGACTGGT GGTCACCCGA CTGCTCTCCA AGGAGACCAG CATCCCAGAG 
GAGCTGCTTG TGACTGTGGT AAAGCCAGGG CTGCCCACCA TAGCCGACTT GTATGTGCTT 
CTGCCTCTGC CAAGGCCCAC AAGGAAGAGG AGCCTCACAA GTGACAAGAG ACTGGCAGCC 
GTGCAGCAGG CGCTGAACTC TCATAGAATC AGCTTCATCC TTCGAGGAGG GCTTCGTATC 
CTGGTGGAGC TGAGGGACAC AGACACAGGT CCTCAGAGGC CAGGTGGCAG TGGTGGCTAC 
TGGGCCGTGG TGGTCCTCTT TGTCATTGGG CTCTTTGCAG TAGGAGCATT CATCCTCTAC 
AAGTTCAAAA GGAAACGTCC AGGCAGGACA GTGTACGCCC AGATGCACAA TGAGAAGGAA 
CAGGAGATGA CAAGTCCCGT GAGTCACAGT GAGGATGCCC AGAGCACCAT GCAGGGCAAC 
CACTCAGGGG TGGTCCTGAG CATCAACTCT CGTGAGATGC ATAGCTACCT GGTGGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_112151.2
CDS	95..3574
Translation	MAHRGPPSAPKRPGPTAPDRSFQALLPPCWPRSWPLLLLLLVLVAACGAMGRSPQPGRQGPGVQITRLLPAGRTESGDRKDPQARESEPSVPGLGPGSASGPSTDGAPAPGKGRRARAVPVAGAASASRAQVSLISTSFVLKGDATHNQAMVHWTGENSSVILILTKYYHADMGKVLESSLWRSSDFGTTYTKLTLQPGVTTVIDNFYICPANKRKIILVSSSLGDREQSLFLSTDEGATFQKYPVPFLVEMLLFHPKEEDKVLAYTKDSKLYVSSDLGKKWTLLQERVTKDHVFWAVSGVDDDPNLVHVEAQDLSGGYRYYTCLIYNCSAQPHIAPFSGPIDRGSLTVQDEYIFLKATSTNRTKYYVSYRRSDFVLMKLPKYALPKDLQIISTDEQQVFVAVQEWNQVDTYNLYQSDLRGVRYSLVLENVRSSRQAEENVVIDILEVRGVKGVFLANQKVDGKVTTVITYNKGRDWDYLRPPSTDMNGKPTNCQPPDCYLHLHLRWADNPYVSGTVHTKDTAPGLIMGAGNLGSQLVEYKEEMYITSDCGHTWRQVFEEEHHVLYLDHGGVIAAIKDTSIPLKILKFSVDEGHTWSTHNFTSTSVFVDGLLSEPGDETLVMTVFGHISFRSDWELVKVDFRPSFPRQCGEDDYSSWDLTDLQGDHCIMGQQRSYRKRKSTSWCVKGRSFTSALTSRVCKCRDSDFLCDYGFERSSSSESTANKCSANFWFNPLSPPEDCVLGQTYTSSLGYRKVVSNVCEGGVDLQQSPVQLQCPLQAPRGLQVSIRGEAVAVRPREDVLFVVRQEQGDVLTTKYQVDLGDGFKAMYVNLTLTGEPIRHHYESPGIYRVSVRAENMAGHDEAVLFVQVNSPLQALYLEVVPVIGVNQEVNLTAVLLPLNPNLTVFYWWIGHSLQPLLSLDNSVTTKFTDAGDVRVTVQAACGNSVLQDSRLVRVLDQFQVVPLRFSRELDTFNPNTPEWREDVGLVVTRLLSKETSIPEELLVTVVKPGLPTIADLYVLLPLPRPTRKRSLTSDKRLAAVQQALNSHRISFILRGGLRILVELRDTDTGPQRPGGSGGYWAVVVLFVIGLFAVGAFILYKFKRKRPGRTVYAQMHNEKEQEMTSPVSHSEDAQSTMQGNHSGVVLSINSREMHSYLVG

Target ORF information:

RefSeq Version	NM_030889.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus sortilin-related VPS10 domain containing receptor 2 (Sorcs2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_030889.2

ORF Insert Sequence:

ATGGCGCACC GGGGACCCCC GAGCGCCCCG AAGCGTCCTG GCCCTACTGC GCCGGACCGG 
AGCTTTCAGG CTCTGCTGCC GCCGTGCTGG CCACGTTCGT GGCCGCTGCT GCTGCTGCTG 
CTGGTGCTGG TGGCTGCCTG CGGAGCGATG GGGCGCTCCC CCCAGCCCGG GCGCCAGGGT 
CCCGGTGTGC AGATCACTAG GCTGCTGCCC GCGGGACGCA CGGAGTCCGG CGATCGCAAA 
GATCCACAGG CACGAGAATC AGAACCCAGC GTCCCGGGTC TCGGTCCGGG TTCTGCTTCG 
GGTCCCAGCA CCGATGGCGC CCCAGCTCCG GGCAAGGGGC GCAGGGCTCG GGCGGTGCCG 
GTGGCCGGTG CGGCTTCGGC TTCGCGCGCA CAGGTCTCGC TCATCAGCAC GTCGTTCGTG 
CTCAAGGGAG ACGCGACGCA CAACCAGGCG ATGGTACACT GGACAGGAGA GAACAGCAGC 
GTCATCTTGA TCCTGACAAA GTACTACCAT GCAGACATGG GCAAGGTTCT GGAAAGTTCT 
CTGTGGAGGT CCTCAGATTT TGGGACAACC TACACCAAGC TTACTCTCCA GCCTGGTGTC 
ACCACTGTCA TTGACAACTT CTATATCTGC CCAGCTAACA AAAGGAAGAT CATCCTGGTG 
AGCTCATCCC TCGGTGACCG GGAACAGAGC CTCTTCCTCA GCACTGATGA GGGCGCCACG 
TTCCAGAAGT ATCCTGTCCC CTTCCTTGTG GAGATGCTCC TCTTCCACCC GAAGGAGGAG 
GACAAGGTGC TGGCCTACAC CAAGGACAGC AAGCTGTATG TGTCATCGGA CCTGGGAAAG 
AAGTGGACAC TTCTGCAGGA ACGGGTGACC AAGGACCACG TGTTCTGGGC TGTGTCTGGG 
GTGGATGACG ACCCAAACTT GGTCCACGTG GAAGCTCAGG ACCTCAGTGG AGGCTATCGG 
TACTACACGT GTCTGATCTA CAACTGCTCA GCCCAGCCAC ACATAGCACC CTTCTCCGGC 
CCCATTGACC GCGGGTCCCT GACCGTGCAG GATGAGTACA TCTTTTTGAA GGCAACATCA 
ACAAACCGAA CCAAGTACTA TGTCTCCTAT CGCCGAAGTG ACTTTGTCCT GATGAAGCTG 
CCCAAGTATG CCCTGCCCAA GGACCTACAG ATCATCAGCA CGGATGAGCA GCAGGTGTTT 
GTGGCCGTAC AGGAGTGGAA CCAGGTAGAC ACCTACAACC TGTACCAGTC AGACCTGCGT 
GGGGTTCGCT ATTCCCTGGT GCTGGAGAAT GTGCGCAGCT CGAGGCAAGC CGAGGAGAAC 
GTGGTCATCG ACATCCTTGA GGTCAGAGGG GTGAAGGGAG TCTTCTTGGC AAACCAGAAA 
GTGGATGGCA AGGTGACCAC AGTCATAACC TACAACAAGG GCCGTGACTG GGATTACCTG 
AGGCCACCCA GCACCGACAT GAATGGGAAG CCCACCAACT GCCAGCCGCC GGACTGTTAC 
CTGCACCTGC ACTTGCGGTG GGCAGACAAC CCCTATGTGT CAGGCACGGT ACACACCAAG 
GACACTGCCC CTGGTCTCAT CATGGGTGCA GGTAACCTGG GCTCACAGCT GGTGGAGTAT 
AAAGAGGAGA TGTACATCAC ATCTGACTGC GGGCACACCT GGAGGCAGGT CTTTGAGGAA 
GAGCACCATG TGTTGTACCT GGACCACGGT GGTGTCATTG CCGCCATCAA GGACACCTCC 
ATCCCCCTGA AGATCCTCAA GTTCAGCGTG GATGAGGGCC ACACGTGGAG CACACACAAC 
TTCACCAGCA CCTCAGTGTT CGTGGATGGG TTGCTGAGCG AGCCAGGGGA TGAGACGCTG 
GTCATGACGG TCTTTGGTCA CATCAGCTTC CGCTCTGACT GGGAGCTGGT CAAGGTTGAC 
TTCCGGCCCT CCTTCCCCCG GCAGTGTGGC GAGGATGACT ACAGCTCCTG GGACCTCACT 
GACCTCCAGG GTGATCACTG CATCATGGGC CAACAGAGAA GTTACCGGAA GAGAAAGTCC 
ACATCCTGGT GTGTCAAGGG ACGGAGCTTC ACATCAGCAC TCACGTCACG TGTGTGCAAG 
TGCCGGGACT CCGACTTCCT CTGTGACTAC GGGTTTGAGC GCTCATCTTC CTCGGAGTCC 
ACTGCCAACA AGTGCTCTGC CAACTTCTGG TTCAACCCTT TGTCTCCTCC TGAAGACTGT 
GTCTTGGGTC AGACTTACAC TAGTAGCCTT GGGTACCGGA AGGTGGTGTC CAATGTGTGT 
GAAGGTGGTG TGGACCTGCA GCAGAGCCCA GTGCAGCTGC AGTGCCCCCT CCAGGCACCC 
CGGGGCCTGC AGGTGAGCAT CCGAGGAGAG GCAGTGGCCG TGCGGCCTAG AGAAGATGTG 
CTGTTTGTGG TGCGACAGGA ACAGGGTGAT GTCCTGACCA CTAAATATCA GGTGGATCTT 
GGGGATGGCT TCAAGGCCAT GTACGTGAAC CTCACTCTGA CAGGCGAGCC CATTCGACAT 
CACTATGAGA GTCCTGGCAT CTACCGAGTG TCCGTCAGGG CTGAGAACAT GGCAGGCCAT 
GATGAGGCTG TGCTCTTTGT CCAGGTCAAC TCTCCCCTGC AGGCCCTCTA CCTCGAGGTA 
GTTCCTGTCA TTGGCGTCAA CCAGGAGGTG AACCTCACAG CCGTGCTGTT ACCCCTGAAT 
CCCAACCTCA CTGTCTTCTA CTGGTGGATC GGCCACAGCT TGCAGCCTCT GCTTTCCTTG 
GACAACTCGG TGACAACAAA GTTTACGGAC GCTGGGGATG TGCGTGTGAC AGTGCAAGCT 
GCCTGCGGGA ACTCAGTGCT TCAGGACTCC AGGCTCGTCC GTGTGCTCGA TCAGTTCCAG 
GTGGTGCCTC TGCGGTTCTC CAGGGAGCTG GACACCTTTA ACCCCAACAC TCCTGAATGG 
AGGGAAGATG TGGGACTGGT GGTCACCCGA CTGCTCTCCA AGGAGACCAG CATCCCAGAG 
GAGCTGCTTG TGACTGTGGT AAAGCCAGGG CTGCCCACCA TAGCCGACTT GTATGTGCTT 
CTGCCTCTGC CAAGGCCCAC AAGGAAGAGG AGCCTCACAA GTGACAAGAG ACTGGCAGCC 
GTGCAGCAGG CGCTGAACTC TCATAGAATC AGCTTCATCC TTCGAGGAGG GCTTCGTATC 
CTGGTGGAGC TGAGGGACAC AGACACAGGT CCTCAGAGGC CAGGTGGCAG TGGTGGCTAC 
TGGGCCGTGG TGGTCCTCTT TGTCATTGGG CTCTTTGCAG TAGGAGCATT CATCCTCTAC 
AAGTTCAAAA GGAAACGTCC AGGCAGGACA GTGTACGCCC AGATGCACAA TGAGAAGGAA 
CAGGAGATGA CAAGTCCCGT GAGTCACAGT GAGGATGCCC AGAGCACCAT GCAGGGCAAC 
CACTCAGGGG TGGTCCTGAG CATCAACTCT CGTGAGATGC ATAGCTACCT GGTGGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Sorcs2 ( XM_006504202.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006504265.1 Mus musculus sortilin-related VPS10 domain containing receptor 2 (Sorcs2), transcript variant X1, mRNA.

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CloneID	OMu35271
Clone ID Related Accession (Same CDS sequence)	XM_006504202.3 , XM_006504202.4
Accession Version	XM_006504202.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3483bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	VPS10 domain-containing receptor SorCS2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006504202.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGCACC GGGGACCCCC GAGCGCCCCG AAGCGTCCTG GCCCTACTGC GCCGGACCGG 
AGCTTTCAGG CTCTGCTGCC GCCGTGCTGG CCACGTTCGT GGCCGCTGCT GCTGCTGCTG 
CTGGTGCTGG TGGCTGCCTG CGGAGCGATG GGGCGCTCCC CCCAGCCCGG GCGCCAGGGT 
CCCGGTGTGC AGATCACTAG GCTGCTGCCC GCGGGACGCA CGGAGTCCGG CGATCGCAAA 
GATCCACAGG CACGAGAATC AGAACCCAGC GTCCCGGGTC TCGGTCCGGG TTCTGCTTCG 
GGTCCCAGCA CCGATGGCGC CCCAGCTCCG GGCAAGGGGC GCAGGGCTCG GGCGGTGCCG 
GTGGCCGGTG CGGCTTCGGC TTCGCGCGCA CAGGTCTCGC TCATCAGCAC GTCGTTCGTG 
CTCAAGGGAG ACGCGACGCA CAACCAGGCG ATGGTACACT GGACAGGAGA GAACAGCAGC 
GTCATCTTGA TCCTGACAAA GTACTACCAT GCAGACATGG GCAAGGTTCT GGAAAGTTCT 
CTGTGGAGGT CCTCAGATTT TGGGACAACC TACACCAAGC TTACTCTCCA GCCTGGTGTC 
ACCACTGTCA TTGACAACTT CTATATCTGC CCAGCTAACA AAAGGAAGAT CATCCTGGTG 
AGCTCATCCC TCGGTGACCG GGAACAGAGC CTCTTCCTCA GCACTGATGA GGGCGCCACG 
TTCCAGAAGT ATCCTGTCCC CTTCCTTGTG GAGATGCTCC TCTTCCACCC GAAGGAGGAG 
GACAAGGTGC TGGCCTACAC CAAGGACAGC AAGCTGTATG TGTCATCGGA CCTGGGAAAG 
AAGTGGACAC TTCTGCAGGA ACGGGTGACC AAGGACCACG TGTTCTGGGC TGTGTCTGGG 
GTGGATGACG ACCCAAACTT GGTCCACGTG GAAGCTCAGG ACCTCAGTGG AGGCTATCGG 
TACTACACGT GTCTGATCTA CAACTGCTCA GCCCAGCCAC ACATAGCACC CTTCTCCGGC 
CCCATTGACC GCGGGTCCCT GACCGTGCAG GATGAGTACA TCTTTTTGAA GGCAACATCA 
ACAAACCGAA CCAAGTACTA TGTCTCCTAT CGCCGAAGTG ACTTTGTCCT GATGAAGCTG 
CCCAAGTATG CCCTGCCCAA GGACCTACAG ATCATCAGCA CGGATGAGCA GCAGGTGTTT 
GTGGCCGTAC AGGAGTGGAA CCAGGTAGAC ACCTACAACC TGTACCAGTC AGACCTGCGT 
GGGGTTCGCT ATTCCCTGGT GCTGGAGAAT GTGCGCAGCT CGAGGCAAGC CGAGGAGAAC 
GTGGTCATCG ACATCCTTGA GGTCAGAGGG GTGAAGGGAG TCTTCTTGGC AAACCAGAAA 
GTGGATGGCA AGGTGACCAC AGTCATAACC TACAACAAGG GCCGTGACTG GGATTACCTG 
AGGCCACCCA GCACCGACAT GAATGGGAAG CCCACCAACT GCCAGCCGCC GGACTGTTAC 
CTGCACCTGC ACTTGCGGTG GGCAGACAAC CCCTATGTGT CAGGCACGGT ACACACCAAG 
GACACTGCCC CTGGTCTCAT CATGGGTGCA GGTAACCTGG GCTCACAGCT GGTGGAGTAT 
AAAGAGGAGA TGTACATCAC ATCTGACTGC GGGCACACCT GGAGGCAGGT CTTTGAGGAA 
GAGCACCATG TGTTGTACCT GGACCACGGT GGTGTCATTG CCGCCATCAA GGACACCTCC 
ATCCCCCTGA AGATCCTCAA GTTCAGCGTG GATGAGGGCC ACACGTGGAG CACACACAAC 
TTCACCAGCA CCTCAGTGTT CGTGGATGGG TTGCTGAGCG AGCCAGGGGA TGAGACGCTG 
GTCATGACGG TCTTTGGTCA CATCAGCTTC CGCTCTGACT GGGAGCTGGT CAAGGTTGAC 
TTCCGGCCCT CCTTCCCCCG GCAGTGTGGC GAGGATGACT ACAGCTCCTG GGACCTCACT 
GACCTCCAGG GTGATCACTG CATCATGGGC CAACAGAGAA GTTACCGGAA GAGAAAGTCC 
ACATCCTGGT GTGTCAAGGG ACGGAGCTTC ACATCAGCAC TCACGTCACG TGTGTGCAAG 
TGCCGGGACT CCGACTTCCT CTGTGACTAC GGGTTTGAGC GCTCATCTTC CTCGGAGTCC 
ACTGCCAACA AGTGCTCTGC CAACTTCTGG TTCAACCCTT TGTCTCCTCC TGAAGACTGT 
GTCTTGGGTC AGACTTACAC TAGTAGCCTT GGGTACCGGA AGGTGGTGTC CAATGTGTGT 
GAAGGTGGTG TGGACCTGCA GCAGAGCCCA GTGCAGCTGC AGTGCCCCCT CCAGGCACCC 
CGGGGCCTGC AGGTGAGCAT CCGAGGAGAG GCAGTGGCCG TGCGGCCTAG AGAAGATGTG 
CTGTTTGTGG TGCGACAGGA ACAGGGTGAT GTCCTGACCA CTAAATATCA GGTGGATCTT 
GGGGATGGCT TCAAGGCCAT GTACGTGAAC CTCACTCTGA CAGGCGAGCC CATTCGACAT 
CACTATGAGA GTCCTGGCAT CTACCGAGTG TCCGTCAGGG CTGAGAACAT GGCAGGCCAT 
GATGAGGCTG TGCTCTTTGT CCAGGTCAAC TCTCCCCTGC AGGCCCTCTA CCTCGAGGTA 
GTTCCTGTCA TTGGCGTCAA CCAGGAGGTG AACCTCACAG CCGTGCTGTT ACCCCTGAAT 
CCCAACCTCA CTGTCTTCTA CTGGTGGATC GGCCACAGCT TGCAGCCTCT GCTTTCCTTG 
GACAACTCGG TGACAACAAA GTTTACGGAC GCTGGGGATG TGCGTGTGAC AGTGCAAGCT 
GCCTGCGGGA ACTCAGTGCT TCAGGACTCC AGGCTCGTCC GTGTGCTCGA TCAGTTCCAG 
GTGGTGCCTC TGCGGTTCTC CAGGGAGCTG GACACCTTTA ACCCCAACAC TCCTGAATGG 
AGGGAAGATG TGGGACTGGT GGTCACCCGA CTGCTCTCCA AGGAGACCAG CATCCCAGAG 
GAGCTGCTTG TGACTGTGGT AAAGCCAGGG CTGCCCACCA TAGCCGACTT GTATGTGCTT 
CTGCCTCTGC CAAGGCCCAC AAGGAAGAGG AGCCTCACAA GTGACAAGAG ACTGGCAGCC 
GTGCAGCAGG CGCTGAACTC TCATAGAATC AGCTTCATCC TTCGAGGAGG GCTTCGTATC 
CTGGTGGAGC TGAGGGACAC AGACACAGGT CCTCAGAGGC CAGGTGGCAG TGGTGGCTAC 
TGGGCCGTGG TGGTCCTCTT TGTCATTGGG CTCTTTGCAG TAGGAGCATT CATCCTCTAC 
AAGTTCAAAA GCAGGAAACG TCCAGGCAGG ACAGTGTACG CCCAGATGCA CAATGAGAAG 
GAACAGGAGA TGACAAGTCC CGTGAGTCAC AGTGAGGATG CCCAGAGCAC CATGCAGGGC 
AACCACTCAG GGGTGGTCCT GAGCATCAAC TCTCGTGAGA TGCATAGCTA CCTGGTGGGC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006504265.1
CDS	119..3601
Translation	MAHRGPPSAPKRPGPTAPDRSFQALLPPCWPRSWPLLLLLLVLVAACGAMGRSPQPGRQGPGVQITRLLPAGRTESGDRKDPQARESEPSVPGLGPGSASGPSTDGAPAPGKGRRARAVPVAGAASASRAQVSLISTSFVLKGDATHNQAMVHWTGENSSVILILTKYYHADMGKVLESSLWRSSDFGTTYTKLTLQPGVTTVIDNFYICPANKRKIILVSSSLGDREQSLFLSTDEGATFQKYPVPFLVEMLLFHPKEEDKVLAYTKDSKLYVSSDLGKKWTLLQERVTKDHVFWAVSGVDDDPNLVHVEAQDLSGGYRYYTCLIYNCSAQPHIAPFSGPIDRGSLTVQDEYIFLKATSTNRTKYYVSYRRSDFVLMKLPKYALPKDLQIISTDEQQVFVAVQEWNQVDTYNLYQSDLRGVRYSLVLENVRSSRQAEENVVIDILEVRGVKGVFLANQKVDGKVTTVITYNKGRDWDYLRPPSTDMNGKPTNCQPPDCYLHLHLRWADNPYVSGTVHTKDTAPGLIMGAGNLGSQLVEYKEEMYITSDCGHTWRQVFEEEHHVLYLDHGGVIAAIKDTSIPLKILKFSVDEGHTWSTHNFTSTSVFVDGLLSEPGDETLVMTVFGHISFRSDWELVKVDFRPSFPRQCGEDDYSSWDLTDLQGDHCIMGQQRSYRKRKSTSWCVKGRSFTSALTSRVCKCRDSDFLCDYGFERSSSSESTANKCSANFWFNPLSPPEDCVLGQTYTSSLGYRKVVSNVCEGGVDLQQSPVQLQCPLQAPRGLQVSIRGEAVAVRPREDVLFVVRQEQGDVLTTKYQVDLGDGFKAMYVNLTLTGEPIRHHYESPGIYRVSVRAENMAGHDEAVLFVQVNSPLQALYLEVVPVIGVNQEVNLTAVLLPLNPNLTVFYWWIGHSLQPLLSLDNSVTTKFTDAGDVRVTVQAACGNSVLQDSRLVRVLDQFQVVPLRFSRELDTFNPNTPEWREDVGLVVTRLLSKETSIPEELLVTVVKPGLPTIADLYVLLPLPRPTRKRSLTSDKRLAAVQQALNSHRISFILRGGLRILVELRDTDTGPQRPGGSGGYWAVVVLFVIGLFAVGAFILYKFKSRKRPGRTVYAQMHNEKEQEMTSPVSHSEDAQSTMQGNHSGVVLSINSREMHSYLVG

Target ORF information:

RefSeq Version	XM_006504202.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus sortilin-related VPS10 domain containing receptor 2 (Sorcs2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006504202.3

ORF Insert Sequence:

ATGGCGCACC GGGGACCCCC GAGCGCCCCG AAGCGTCCTG GCCCTACTGC GCCGGACCGG 
AGCTTTCAGG CTCTGCTGCC GCCGTGCTGG CCACGTTCGT GGCCGCTGCT GCTGCTGCTG 
CTGGTGCTGG TGGCTGCCTG CGGAGCGATG GGGCGCTCCC CCCAGCCCGG GCGCCAGGGT 
CCCGGTGTGC AGATCACTAG GCTGCTGCCC GCGGGACGCA CGGAGTCCGG CGATCGCAAA 
GATCCACAGG CACGAGAATC AGAACCCAGC GTCCCGGGTC TCGGTCCGGG TTCTGCTTCG 
GGTCCCAGCA CCGATGGCGC CCCAGCTCCG GGCAAGGGGC GCAGGGCTCG GGCGGTGCCG 
GTGGCCGGTG CGGCTTCGGC TTCGCGCGCA CAGGTCTCGC TCATCAGCAC GTCGTTCGTG 
CTCAAGGGAG ACGCGACGCA CAACCAGGCG ATGGTACACT GGACAGGAGA GAACAGCAGC 
GTCATCTTGA TCCTGACAAA GTACTACCAT GCAGACATGG GCAAGGTTCT GGAAAGTTCT 
CTGTGGAGGT CCTCAGATTT TGGGACAACC TACACCAAGC TTACTCTCCA GCCTGGTGTC 
ACCACTGTCA TTGACAACTT CTATATCTGC CCAGCTAACA AAAGGAAGAT CATCCTGGTG 
AGCTCATCCC TCGGTGACCG GGAACAGAGC CTCTTCCTCA GCACTGATGA GGGCGCCACG 
TTCCAGAAGT ATCCTGTCCC CTTCCTTGTG GAGATGCTCC TCTTCCACCC GAAGGAGGAG 
GACAAGGTGC TGGCCTACAC CAAGGACAGC AAGCTGTATG TGTCATCGGA CCTGGGAAAG 
AAGTGGACAC TTCTGCAGGA ACGGGTGACC AAGGACCACG TGTTCTGGGC TGTGTCTGGG 
GTGGATGACG ACCCAAACTT GGTCCACGTG GAAGCTCAGG ACCTCAGTGG AGGCTATCGG 
TACTACACGT GTCTGATCTA CAACTGCTCA GCCCAGCCAC ACATAGCACC CTTCTCCGGC 
CCCATTGACC GCGGGTCCCT GACCGTGCAG GATGAGTACA TCTTTTTGAA GGCAACATCA 
ACAAACCGAA CCAAGTACTA TGTCTCCTAT CGCCGAAGTG ACTTTGTCCT GATGAAGCTG 
CCCAAGTATG CCCTGCCCAA GGACCTACAG ATCATCAGCA CGGATGAGCA GCAGGTGTTT 
GTGGCCGTAC AGGAGTGGAA CCAGGTAGAC ACCTACAACC TGTACCAGTC AGACCTGCGT 
GGGGTTCGCT ATTCCCTGGT GCTGGAGAAT GTGCGCAGCT CGAGGCAAGC CGAGGAGAAC 
GTGGTCATCG ACATCCTTGA GGTCAGAGGG GTGAAGGGAG TCTTCTTGGC AAACCAGAAA 
GTGGATGGCA AGGTGACCAC AGTCATAACC TACAACAAGG GCCGTGACTG GGATTACCTG 
AGGCCACCCA GCACCGACAT GAATGGGAAG CCCACCAACT GCCAGCCGCC GGACTGTTAC 
CTGCACCTGC ACTTGCGGTG GGCAGACAAC CCCTATGTGT CAGGCACGGT ACACACCAAG 
GACACTGCCC CTGGTCTCAT CATGGGTGCA GGTAACCTGG GCTCACAGCT GGTGGAGTAT 
AAAGAGGAGA TGTACATCAC ATCTGACTGC GGGCACACCT GGAGGCAGGT CTTTGAGGAA 
GAGCACCATG TGTTGTACCT GGACCACGGT GGTGTCATTG CCGCCATCAA GGACACCTCC 
ATCCCCCTGA AGATCCTCAA GTTCAGCGTG GATGAGGGCC ACACGTGGAG CACACACAAC 
TTCACCAGCA CCTCAGTGTT CGTGGATGGG TTGCTGAGCG AGCCAGGGGA TGAGACGCTG 
GTCATGACGG TCTTTGGTCA CATCAGCTTC CGCTCTGACT GGGAGCTGGT CAAGGTTGAC 
TTCCGGCCCT CCTTCCCCCG GCAGTGTGGC GAGGATGACT ACAGCTCCTG GGACCTCACT 
GACCTCCAGG GTGATCACTG CATCATGGGC CAACAGAGAA GTTACCGGAA GAGAAAGTCC 
ACATCCTGGT GTGTCAAGGG ACGGAGCTTC ACATCAGCAC TCACGTCACG TGTGTGCAAG 
TGCCGGGACT CCGACTTCCT CTGTGACTAC GGGTTTGAGC GCTCATCTTC CTCGGAGTCC 
ACTGCCAACA AGTGCTCTGC CAACTTCTGG TTCAACCCTT TGTCTCCTCC TGAAGACTGT 
GTCTTGGGTC AGACTTACAC TAGTAGCCTT GGGTACCGGA AGGTGGTGTC CAATGTGTGT 
GAAGGTGGTG TGGACCTGCA GCAGAGCCCA GTGCAGCTGC AGTGCCCCCT CCAGGCACCC 
CGGGGCCTGC AGGTGAGCAT CCGAGGAGAG GCAGTGGCCG TGCGGCCTAG AGAAGATGTG 
CTGTTTGTGG TGCGACAGGA ACAGGGTGAT GTCCTGACCA CTAAATATCA GGTGGATCTT 
GGGGATGGCT TCAAGGCCAT GTACGTGAAC CTCACTCTGA CAGGCGAGCC CATTCGACAT 
CACTATGAGA GTCCTGGCAT CTACCGAGTG TCCGTCAGGG CTGAGAACAT GGCAGGCCAT 
GATGAGGCTG TGCTCTTTGT CCAGGTCAAC TCTCCCCTGC AGGCCCTCTA CCTCGAGGTA 
GTTCCTGTCA TTGGCGTCAA CCAGGAGGTG AACCTCACAG CCGTGCTGTT ACCCCTGAAT 
CCCAACCTCA CTGTCTTCTA CTGGTGGATC GGCCACAGCT TGCAGCCTCT GCTTTCCTTG 
GACAACTCGG TGACAACAAA GTTTACGGAC GCTGGGGATG TGCGTGTGAC AGTGCAAGCT 
GCCTGCGGGA ACTCAGTGCT TCAGGACTCC AGGCTCGTCC GTGTGCTCGA TCAGTTCCAG 
GTGGTGCCTC TGCGGTTCTC CAGGGAGCTG GACACCTTTA ACCCCAACAC TCCTGAATGG 
AGGGAAGATG TGGGACTGGT GGTCACCCGA CTGCTCTCCA AGGAGACCAG CATCCCAGAG 
GAGCTGCTTG TGACTGTGGT AAAGCCAGGG CTGCCCACCA TAGCCGACTT GTATGTGCTT 
CTGCCTCTGC CAAGGCCCAC AAGGAAGAGG AGCCTCACAA GTGACAAGAG ACTGGCAGCC 
GTGCAGCAGG CGCTGAACTC TCATAGAATC AGCTTCATCC TTCGAGGAGG GCTTCGTATC 
CTGGTGGAGC TGAGGGACAC AGACACAGGT CCTCAGAGGC CAGGTGGCAG TGGTGGCTAC 
TGGGCCGTGG TGGTCCTCTT TGTCATTGGG CTCTTTGCAG TAGGAGCATT CATCCTCTAC 
AAGTTCAAAA GCAGGAAACG TCCAGGCAGG ACAGTGTACG CCCAGATGCA CAATGAGAAG 
GAACAGGAGA TGACAAGTCC CGTGAGTCAC AGTGAGGATG CCCAGAGCAC CATGCAGGGC 
AACCACTCAG GGGTGGTCCT GAGCATCAAC TCTCGTGAGA TGCATAGCTA CCTGGTGGGC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

SorCS2-mediated NR2A trafficking regulates motor deficits in Huntington's disease.
JCI insight2(9)(2017 May)
Ma Q,Yang J,Milner TA,Vonsattel JG,Palko ME,Tessarollo L,Hempstead BL

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Sorcs2 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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