Ggnbp1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ggnbp1
Entrez Gene ID	70772
Full Name	gametogenetin binding protein 1
Synonyms	0610031G08Rik,mdf
General protein information	Preferred Names gametogenetin binding protein 1 Names gametogenetin-binding protein 1 deubiquitinating enzyme Usp15 gametogenin binding protein 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 17 Map Location: 17\|17 A3.3

mRNA and Protein(s)

mRNA	Protein	Name
NM_027544.2	NP_081820.2	gametogenetin-binding protein 1 isoform a
NM_001251881.1	NP_001238810.1	gametogenetin-binding protein 1 isoform b

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	LOC100612712	XP_003311271.1
Rattus norvegicus (Norway rat)	Ggnbp1	NP_001009972.1
Mus musculus (house mouse)	Ggnbp1	NP_081820.2
Bos taurus (cattle)	LOC516410	NP_001092463.1

Gene Ontology
Bibliography

Related articles in PubMed

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H
Nucleic acids research42(Database issue)D802-9(2014 Jan)

Mouse Dfa is a repressor of TATA-box promoters and interacts with the Abt1 activator of basal transcription.
Brower CS, Veiga L, Jones RH, Varshavsky A
The Journal of biological chemistry285(22)17218-34(2010 May)

A novel potential role for gametogenetin-binding protein 1 (GGNBP1) in mitochondrial morphogenesis during spermatogenesis in mice.
Aihara T, Nakamura N, Honda S, Hirose S
Biology of reproduction80(4)762-70(2009 Apr)

Germ-cell specific protein gametogenetin protein 2 (GGN2), expression in the testis, and association with intracellular membrane.
Zhao Q, Zhou Y, Cao Z, Zhu H, Huang P, Lu B
Molecular reproduction and development72(1)31-9(2005 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

GGNBP1 is involved in spermatogenesis by modifying mitochondrial dynamics and morphology.
Title: A novel potential role for gametogenetin-binding protein 1 (GGNBP1) in mitochondrial morphogenesis during spermatogenesis in mice.

A testicular germ cell-specific protein interacting with GGN1. The protein seems to associate with the membrane system in the germ cell.
Title: Identification and characterization of a novel testicular germ cell-specific gene Ggnbp1.

The following Ggnbp1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ggnbp1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu04330	NM_027544.2 Latest version!	Mus musculus gametogenetin binding protein 1 (Ggnbp1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
OMu04673	NM_001251881.1 Latest version!	Mus musculus gametogenetin binding protein 1 (Ggnbp1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$139.30 $199.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ggnbp1 ( NM_027544.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_081820.2 Mus musculus gametogenetin binding protein 1 (Ggnbp1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu04330
Clone ID Related Accession (Same CDS sequence)	NM_027544.2
Accession Version	NM_027544.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1113bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-01-20
Organism	Mus musculus(house mouse)
Product	gametogenetin-binding protein 1 isoform a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AY141192.1, AK077129.1 and BB018101.1. On Sep 15, 2007 this sequence version replaced NM_027544.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a). ##Evidence-Data-START## Transcript exon combination :: AY141192.1, AB250379.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCAGCCC CGGCGCGGAC CCCTCGGTCA CGGATCTTAG GCTGCTCCTC CATGCTGCGC 
TTTCTCCGAA ACCTGGTGGG GAGTAAGGGC GGTTCTAAGA GCACTAACAA GCCCCTGACC 
AGGAGCCAGC CCAGCTCCTC ATGGGAGCAA GATGTTGTCT CCCCAATGAT GGGCCACCAG 
GGAGGTCGTG GGAGGAAGGA GCCCCGGGCC AAGGTCCACT CTGCAGCTTC CTCTAATGGG 
AAGAGGGAGC CCCCGCCCAG GGTTCTCTCT GCAGCTCCCT CCAACCCGAG GCATGATGCC 
TTTGAGCTGG GCACTGGGGA CTCAGGGTCC CAGACCCTCA CCTCCAAGGA TGTCCCGAAG 
CTAAGGGCCC AGGGTGTTGA GGTAACATCA GTTCCTCTCA GAGGAACCTG GGAGGTTCTG 
GAGCAGCTAC CTGAGAAGAA AGGAGAGGAG GAGGAGCCAG TAGGGGAGGT CTCCGGGGCC 
TCAGACAGGG AGCATTTTGG CCAGGCCCTG GAGACAGAAC AAGGATGCTT ACAGTGGGTT 
CCGGGACCAC TGGCGCTCAC CCCTGGGGCC TTCATCAAGG AGGAAGAGGA TGAACACTGC 
CCAATTGAGT TTGGAGACCT CAAGCCGTCC TCTTGCAAGG TGGGGTCCAC CCCGTGGAAC 
TATCTCCTTG GCTTGTACAA GCAGCTCCAG AAGTCAGCCA TGGCCAAGGC TCAGAGACCA 
GCTGCGCCTC AGTTGGCTCT CAAGGATGGC TTGCCCCACG AGGAGAAAGG GGAGAGAGAA 
GAAGCGGTGG ATGAGAGCTG TCCCAAGTGG TGTGCCCCTC GCGCCTCTAG CGACGAGAGC 
TGTCCCAAGT GGTGTGCCCC GCGTGCCTCC ACCTACCAGT CGCCGCTGCA AAAGAAGTTT 
AGGTCTACAG ATACAGTGGG TTTTGTGGAG TCGGAGCTGA AGAAGATTCT GTCAGTGCAA 
CGAGAGGCTC GCCTCTGGAA GGTGGGCAAC CCCGAGGGCC GGGAGCTGCT GACCCAGCCA 
GACATCACAC TGGAGGAGGC TGGCATGGTG GACGGCCAGC ACCTGCTCCT GGAGGAGATG 
GACGAGATGG GAAACTGGCC CCCTCCAGAT TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_081820.2
CDS	201..1313
Translation	MAAPARTPRSRILGCSSMLRFLRNLVGSKGGSKSTNKPLTRSQPSSSWEQDVVSPMMGHQGGRGRKEPRAKVHSAASSNGKREPPPRVLSAAPSNPRHDAFELGTGDSGSQTLTSKDVPKLRAQGVEVTSVPLRGTWEVLEQLPEKKGEEEEPVGEVSGASDREHFGQALETEQGCLQWVPGPLALTPGAFIKEEEDEHCPIEFGDLKPSSCKVGSTPWNYLLGLYKQLQKSAMAKAQRPAAPQLALKDGLPHEEKGEREEAVDESCPKWCAPRASSDESCPKWCAPRASTYQSPLQKKFRSTDTVGFVESELKKILSVQREARLWKVGNPEGRELLTQPDITLEEAGMVDGQHLLLEEMDEMGNWPPPD

Target ORF information:

RefSeq Version	NM_027544.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus gametogenetin binding protein 1 (Ggnbp1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_027544.2

ORF Insert Sequence:

ATGGCAGCCC CGGCGCGGAC CCCTCGGTCA CGGATCTTAG GCTGCTCCTC CATGCTGCGC 
TTTCTCCGAA ACCTGGTGGG GAGTAAGGGC GGTTCTAAGA GCACTAACAA GCCCCTGACC 
AGGAGCCAGC CCAGCTCCTC ATGGGAGCAA GATGTTGTCT CCCCAATGAT GGGCCACCAG 
GGAGGTCGTG GGAGGAAGGA GCCCCGGGCC AAGGTCCACT CTGCAGCTTC CTCTAATGGG 
AAGAGGGAGC CCCCGCCCAG GGTTCTCTCT GCAGCTCCCT CCAACCCGAG GCATGATGCC 
TTTGAGCTGG GCACTGGGGA CTCAGGGTCC CAGACCCTCA CCTCCAAGGA TGTCCCGAAG 
CTAAGGGCCC AGGGTGTTGA GGTAACATCA GTTCCTCTCA GAGGAACCTG GGAGGTTCTG 
GAGCAGCTAC CTGAGAAGAA AGGAGAGGAG GAGGAGCCAG TAGGGGAGGT CTCCGGGGCC 
TCAGACAGGG AGCATTTTGG CCAGGCCCTG GAGACAGAAC AAGGATGCTT ACAGTGGGTT 
CCGGGACCAC TGGCGCTCAC CCCTGGGGCC TTCATCAAGG AGGAAGAGGA TGAACACTGC 
CCAATTGAGT TTGGAGACCT CAAGCCGTCC TCTTGCAAGG TGGGGTCCAC CCCGTGGAAC 
TATCTCCTTG GCTTGTACAA GCAGCTCCAG AAGTCAGCCA TGGCCAAGGC TCAGAGACCA 
GCTGCGCCTC AGTTGGCTCT CAAGGATGGC TTGCCCCACG AGGAGAAAGG GGAGAGAGAA 
GAAGCGGTGG ATGAGAGCTG TCCCAAGTGG TGTGCCCCTC GCGCCTCTAG CGACGAGAGC 
TGTCCCAAGT GGTGTGCCCC GCGTGCCTCC ACCTACCAGT CGCCGCTGCA AAAGAAGTTT 
AGGTCTACAG ATACAGTGGG TTTTGTGGAG TCGGAGCTGA AGAAGATTCT GTCAGTGCAA 
CGAGAGGCTC GCCTCTGGAA GGTGGGCAAC CCCGAGGGCC GGGAGCTGCT GACCCAGCCA 
GACATCACAC TGGAGGAGGC TGGCATGGTG GACGGCCAGC ACCTGCTCCT GGAGGAGATG 
GACGAGATGG GAAACTGGCC CCCTCCAGAT TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ggnbp1 ( NM_001251881.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001238810.1 Mus musculus gametogenetin binding protein 1 (Ggnbp1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu04673
Clone ID Related Accession (Same CDS sequence)	NM_001251881.1
Accession Version	NM_001251881.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 789bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Mus musculus(house mouse)
Product	gametogenetin-binding protein 1 isoform b
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CF585840.1, AA388242.1 and CO041745.1. On Oct 22, 2011 this sequence version replaced XR_105889.1. Transcript Variant: This variant (2) lacks an exon and includes two alternate exons in the 5' UTR and CDS, compared to variant 1. It encodes isoform b, which is shorter and has a distinct N-terminus, compared to isoform a. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTGCTCAC GAGCCCGGCG ACCCTCTCGT CCTGCCTCCA GGACTGACCG ACCTGGGATT 
GCAGACATGA GCTACCACAC CCGGCTCACA CAGACCTGGG ATGTGAACCC CAAGTCCAGG 
GACCAGCCTG ATCTCCACGC CCAACCACTT CAGAGAAGAG AAAGGGAGCA TTTTGGCCAG 
GCCCTGGAGA CAGAACAAGG ATGCTTACAG TGGGTTCCGG GACCACTGGC GCTCACCCCT 
GGGGCCTTCA TCAAGGAGGA AGAGGATGAA CACTGCCCAA TTGAGTTTGG AGACCTCAAG 
CCGTCCTCTT GCAAGGTGGG GTCCACCCCG TGGAACTATC TCCTTGGCTT GTACAAGCAG 
CTCCAGAAGT CAGCCATGGC CAAGGCTCAG AGACCAGCTG CGCCTCAGTT GGCTCTCAAG 
GATGGCTTGC CCCACGAGGA GAAAGGGGAG AGAGAAGAAG CGGTGGATGA GAGCTGTCCC 
AAGTGGTGTG CCCCTCGCGC CTCTAGCGAC GAGAGCTGTC CCAAGTGGTG TGCCCCGCGT 
GCCTCCACCT ACCAGTCGCC GCTGCAAAAG AAGTTTAGGT CTACAGATAC AGTGGGTTTT 
GTGGAGTCGG AGCTGAAGAA GATTCTGTCA GTGCAACGAG AGGCTCGCCT CTGGAAGGTG 
GGCAACCCCG AGGGCCGGGA GCTGCTGACC CAGCCAGACA TCACACTGGA GGAGGCTGGC 
ATGGTGGACG GCCAGCACCT GCTCCTGGAG GAGATGGACG AGATGGGAAA CTGGCCCCCT 
CCAGATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001238810.1
CDS	96..884
Translation	MCSRARRPSRPASRTDRPGIADMSYHTRLTQTWDVNPKSRDQPDLHAQPLQRREREHFGQALETEQGCLQWVPGPLALTPGAFIKEEEDEHCPIEFGDLKPSSCKVGSTPWNYLLGLYKQLQKSAMAKAQRPAAPQLALKDGLPHEEKGEREEAVDESCPKWCAPRASSDESCPKWCAPRASTYQSPLQKKFRSTDTVGFVESELKKILSVQREARLWKVGNPEGRELLTQPDITLEEAGMVDGQHLLLEEMDEMGNWPPPD

Target ORF information:

RefSeq Version	NM_001251881.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus gametogenetin binding protein 1 (Ggnbp1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001251881.1

ORF Insert Sequence:

ATGTGCTCAC GAGCCCGGCG ACCCTCTCGT CCTGCCTCCA GGACTGACCG ACCTGGGATT 
GCAGACATGA GCTACCACAC CCGGCTCACA CAGACCTGGG ATGTGAACCC CAAGTCCAGG 
GACCAGCCTG ATCTCCACGC CCAACCACTT CAGAGAAGAG AAAGGGAGCA TTTTGGCCAG 
GCCCTGGAGA CAGAACAAGG ATGCTTACAG TGGGTTCCGG GACCACTGGC GCTCACCCCT 
GGGGCCTTCA TCAAGGAGGA AGAGGATGAA CACTGCCCAA TTGAGTTTGG AGACCTCAAG 
CCGTCCTCTT GCAAGGTGGG GTCCACCCCG TGGAACTATC TCCTTGGCTT GTACAAGCAG 
CTCCAGAAGT CAGCCATGGC CAAGGCTCAG AGACCAGCTG CGCCTCAGTT GGCTCTCAAG 
GATGGCTTGC CCCACGAGGA GAAAGGGGAG AGAGAAGAAG CGGTGGATGA GAGCTGTCCC 
AAGTGGTGTG CCCCTCGCGC CTCTAGCGAC GAGAGCTGTC CCAAGTGGTG TGCCCCGCGT 
GCCTCCACCT ACCAGTCGCC GCTGCAAAAG AAGTTTAGGT CTACAGATAC AGTGGGTTTT 
GTGGAGTCGG AGCTGAAGAA GATTCTGTCA GTGCAACGAG AGGCTCGCCT CTGGAAGGTG 
GGCAACCCCG AGGGCCGGGA GCTGCTGACC CAGCCAGACA TCACACTGGA GGAGGCTGGC 
ATGGTGGACG GCCAGCACCT GCTCCTGGAG GAGATGGACG AGATGGGAAA CTGGCCCCCT 
CCAGATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Nucleic acids research42(Database issue)D802-9(2014 Jan)
Koscielny G,Yaikhom G,Iyer V,Meehan TF,Morgan H,Atienza-Herrero J,Blake A,Chen CK,Easty R,Di Fenza A,Fiegel T,Grifiths M,Horne A,Karp NA,Kurbatova N,Mason JC,Matthews P,Oakley DJ,Qazi A,Regnart J,Retha A,Santos LA,Sneddon DJ,Warren J,Westerberg H,Wilson RJ,Melvin DG,Smedley D,Brown SD,Flicek P,Skarnes WC,Mallon AM,Parkinson H

Mouse Dfa is a repressor of TATA-box promoters and interacts with the Abt1 activator of basal transcription.
The Journal of biological chemistry285(22)17218-34(2010 May)
Brower CS,Veiga L,Jones RH,Varshavsky A

A novel potential role for gametogenetin-binding protein 1 (GGNBP1) in mitochondrial morphogenesis during spermatogenesis in mice.
Biology of reproduction80(4)762-70(2009 Apr)
Aihara T,Nakamura N,Honda S,Hirose S

Germ-cell specific protein gametogenetin protein 2 (GGN2), expression in the testis, and association with intracellular membrane.
Molecular reproduction and development72(1)31-9(2005 Sep)
Zhao Q,Zhou Y,Cao Z,Zhu H,Huang P,Lu B

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Ggnbp1 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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