Sik3 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Sik3
Entrez Gene ID	70661
Full Name	SIK family kinase 3
Synonyms	5730525O22Rik,9030204A07Rik,AI447252,AI846254,AI849445,Qsk,SIK-3,mKIAA0999
General protein information	Preferred Names SIK family kinase 3 Names serine/threonine-protein kinase SIK3 salt-inducible kinase 3 serine/threonine-protein kinase QSK
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 9 Map Location: 9\|9 A5.2

mRNA and Protein(s)

mRNA	Protein	Name
NM_027498.3	NP_081774.3	serine/threonine-protein kinase SIK3
XM_006510590.3	XP_006510653.1	serine/threonine-protein kinase SIK3 isoform X1
XM_006510590.2	XP_006510653.1	serine/threonine-protein kinase SIK3 isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	SIK3	NP_001268678.1
Mus musculus (house mouse)	Sik3	NP_081774.3
Gallus gallus (chicken)	LOC777317	XP_003642652.2
Danio rerio (zebrafish)	zgc:66101	NP_956835.1
Pan troglodytes (chimpanzee)	SIK3	XP_508771.3
Canis lupus familiaris (dog)	SIK3	XP_005619786.1
	SIK3	XP_002799853.1
Bos taurus (cattle)	SIK3	XP_002693070.2
Rattus norvegicus (Norway rat)	Sik3	NP_001258145.1
Xenopus tropicalis (tropical clawed frog)	sik3	XP_004916140.1

Gene Ontology
Bibliography

Related articles in PubMed

Salt-inducible kinase 3 regulates the mammalian circadian clock by destabilizing PER2 protein.
Hayasaka N, Hirano A, Miyoshi Y, Tokuda IT, Yoshitane H, Matsuda J, Fukada Y
eLife6(2017 Dec)

Inhibition of SIK2 and SIK3 during differentiation enhances the anti-inflammatory phenotype of macrophages.
Darling NJ, Toth R, Arthur JS, Clark K
The Biochemical journal474(4)521-537(2017 02)

Forward-genetics analysis of sleep in randomly mutagenized mice.
Funato H, Miyoshi C, Fujiyama T, Kanda T, Sato M, Wang Z, Ma J, Nakane S, Tomita J, Ikkyu A, Kakizaki M, Hotta-Hirashima N, Kanno S, Komiya H, Asano F, Honda T, Kim SJ, Harano K, Muramoto H, Yonezawa T, Mizuno S, Miyazaki S, Connor L, Kumar V, Miura I, Suzuki T, Watanabe A, Abe M, Sugiyama F, Takahashi S, Sakimura K, Hayashi Y, Liu Q, Kume K, Wakana S, Takahashi JS, Yanagisawa M
Nature539(7629)378-383(2016 11)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The data highlight an integral role for SIK2 and SIK3 in innate immunity by preventing the differentiation of macrophages into a potent and stable anti-inflammatory phenotype.
Title: Inhibition of SIK2 and SIK3 during differentiation enhances the anti-inflammatory phenotype of macrophages.

results substantiate the use of a forward-genetics approach for studying sleep behaviours in mice, and demonstrate the role of SIK3 and NALCN in regulating the amount of NREMS and REMS, respectively
Title: Forward-genetics analysis of sleep in randomly mutagenized mice.

Conditional chondrocyte-specific Sik3 knockout mice exhibit thickening of articular cartilage and resistance to surgically induced osteoarthritis.
Title: Pterosin B prevents chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3.

Sik1, Sik2, and Sik3 play a key role as gluconeogenesis suppressors downstream of LKB1 in the liver.
Title: The LKB1-salt-inducible kinase pathway functions as a key gluconeogenic suppressor in the liver.

These results establish the importance of SIK3 as a mitotic regulator and underscore the potential of SIK3 as a druggable antimitotic target.
Title: Salt-inducible kinase 3 is a novel mitotic regulator and a target for enhancing antimitotic therapeutic-mediated cell death.

The following Sik3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Sik3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu42388	XM_006510590.3 Latest version!	Mus musculus SIK family kinase 3 (Sik3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$643.30 $919.00
OMu18881	NM_027498.3 Latest version!	Mus musculus SIK family kinase 3 (Sik3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$727.30 $1039.00
View Old Accession Versions >>
OMu42388	XM_006510590.2	Mus musculus SIK family kinase 3 (Sik3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$643.30 $919.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Sik3 ( XM_006510590.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006510653.1 Mus musculus SIK family kinase 3 (Sik3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu42388
Clone ID Related Accession (Same CDS sequence)	XM_006510590.3 , XM_006510590.2
Accession Version	XM_006510590.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3966bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	serine/threonine-protein kinase SIK3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000075.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006510590.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGCGG CGGCGGCGAG CGGAGCTGGC GGGGTTGCCG TGGCCGGAGC AGGGGGAGCC 
GGGCCGGCCG GCCGCCTGCT GCCTCCGCCC GCCGCGGGGC CCCCGGCAGC CCCCGCCGCA 
GTGCCCCCGG CCGCCGTCCC GGCGCGTCCC ACAGCCCCGG CCTCCCGCGG GTCGATGGCC 
GCTCGCATCG GCTACTACGA GATCGACCGC ACCATCGGCA AGGGCAACTT CGCTGTGGTC 
AAGCGGGCCA CGCACCTCGT CACCAAGGCC AAGGTTGCTA TTAAAATCAT AGATAAGAGC 
CAGCTGGATG AAGAAAACTT GAAGAAGATT TTCCGGGAGG TTCAGATAAT GAAGATGCTT 
TGCCATCCAC ACATCATCAG ACTCTACCAG GTCATGGAGA CAGAGCGCAT GATTTACCTG 
GTGACAGAAT ACGCTAGCGG AGGGGAGATA TTTGACCACT TGGTAGCCCA TGGAAGAATG 
GCAGAGAAGG AAGCTCGACG GAAGTTCAAA CAGATCGTCA CAGCGGTGTA TTTTTGTCAC 
TGTCGGAATA TCGTTCATCG TGATTTAAAA GCCGAAAACT TACTTCTGGA CGCCAATCTG 
AATATCAAAA TAGCAGACTT TGGCTTCAGC AACCTCTTCA CTCCAGGGCA GCTGCTGAAG 
ACGTGGTGTG GCAGCCCTCC CTATGCCGCC CCAGAGCTCT TCGAAGGGAA GGAATATGAT 
GGGCCCAAAG TGGACATATG GAGCCTTGGA GTTGTCCTCT ATGTGCTGGT GTGTGGCGCC 
CTGCCGTTTG ATGGGAGCAC ACTGCAGAAT CTGCGGGCCC GCGTGCTGAG TGGCAAGTTC 
CGCATCCCGT TCTTTATGTC CACAGAGTGT GAGCACTTGA TCCGCCACAT GCTGGTGTTA 
GATCCAAATA AGCGCCTCTC AATGGAACAG ATCTGCAGGC ACAAGTGGAT GAAGCTCGGA 
GATGCAGACC CCAACTTTGA CAGGTTAATA GCGGAGTGCC AGCAACTGAA GGAGGAAAGG 
CAGTCGGACC CCCTCAACGA TGATGTCCTC TTGGCTATGG AAGACATGGG GCTGGACAAG 
GAGCGCACAC TTCAGTCATT AAGGTCAGAT GCCTATGACC ACTATAGTGC AATCTACAGC 
CTGCTGTGCG ATCGACACAA GAAACATAAA ACTCTGCGTC CCGGAGCACT TCCCAGCATG 
CCCCAAGCCA TGACTTTCCA GGCACCAGTC AATCTCCAGG CGGAGCAGAC AGGCACTGCT 
ATGAACCTTA GCGTCCCTCA AGTTCAGCTG ATCAACCCAG AGAACCAAAT TATAGAGCCT 
GACGGGGCTG TGAACTTGGA CAGTGATGAG GGTGAAGAGC CTTCTCCAGA AGCCTTGGTT 
CGCTATTTGT CAATGAGGAG GCACACGGTG GGAGTGGCTG ACCCACGCAC GGAAGTTATG 
GAAGATCTGC AGAAGCTGCT GCCTGGCTTT CCTGGAGTAA ACCCACAGGG TCCATTCCTA 
CAAGTGGCCC CTAACATGAA CTTCACGCAC AACCTGTTGC CCATGCAGAG TCTGCAGCCA 
ACTGGGCAGC TTGAGTACAA GGAACAGTCT CTGTTACAGC CGCCTACACT ACAGCTACTG 
AACGGAATGG GGCCCCTTGG CCGGAGAGCC TCAGATGGAG GCGCCAACAT CCAACTGCAT 
GCCCAGCAGC TGCTCAAGCG CCCACGGGGA CCGTCCCCAC TTGTCACCAT GACACCAGCA 
GTGCCAGCAG TTACCCCTGT GGATGAGGAG AGCTCGGATG GGGAGCCAGA TCAGGAAGCT 
GTGCAGAGCT CCACCTACAA GGACTCCAAC ACCCTGCATC TCCCTACGGA GCGTTTCTCC 
CCCGTGCGCC GGTTCTCAGA CGGGGCTGCA AGCATCCAGG CCTTCAAAGC TCACCTGGAA 
AAAATGGGCA ACAGCAGCAG CATCAAGCAG TTGCAGCAGG AGTGTGAGCA GCTGCAGAAG 
ATGTACGGGG GGCAGGTGGA TGAGAGGACC CTGGAGAAGA CCCAGCAGCA GCATATGTTG 
TACCAGCAGG AGCAGCACCA TCAGATCCTC CAGCAGCAAA TCCAAGATTC TATTTGTCCT 
CCTCAGCCCT CCCCACCTCT TCAGGTTGCC TGTGAAAACC AACCAGCCCT CCTCACCCAC 
CAGCTCCAGA GGTTAAGGAT TCAACCTTCA AGCCCACCCC CCAACCATCC CAGCAACCAT 
CTCTTCAGAC AGCCAAGTAA CAGTCCTCCC CCGGTCAGCA GTGCCATGAT CACGTCTCAC 
GGTGCTACGT CTCCCTCCCA GTTTCAAGGC TTACCCTCCC ATGGTGCAAT CTTCCAGCAG 
CAACCCGAGA ACTGTTCCCC GCCTCCCAGT GTAGCACTAA CCTGCCTGGG CCTACAGCAG 
GCTAGCCAGT CACAGCCAGT GACTATCCAG CTACAGGAGC CAGTTGACAT GCTCAGCAAC 
ATGGCCGGAA CCGCGGCAGG CTCTGCAGGG CGGAGCATCC CCATCAGCCC CAGCGCCAGT 
CAGATTCAGA TACAGCACCG AGCCAGCCTA ATGGCTCCCT TCAGCTATGG GCACCGGCCC 
TTGTCCAAGC AGCTGAGCGC TGACAGTGCA GAGGCCCACA GCTTGAACAT GAATCGGTTC 
TCCCCTGCCA ACTACGACCA GGCGCATTTA CACCCCCATC TGTTTTCGGA CCAGTCCCGA 
GGTTCCCCCA GCAGCTACAG CCCTTCAACA GGAGTGGGGT TTCCTCCAAC TCAAGCCCTG 
AAAGTTCCTC CGCTTGACCA GTTCCCCACT TTCCCTCCCA GTGCCCAGCA GCAGCCACCC 
CACTATACCA CGTCAGCACT ACAGCAGGCC CTGCTATCTC CTACACCGCC AGACTATCCC 
CGACACCAGC AGGTTCCCCA TATCCTTCAA GGACTGCTCT CTCCCCGGCA TTCACTCACC 
GGCCACTCGG ACATTCGGCT GCCTCCGGCA GAGTTTGCAC AGCTCATCAA AAGGCAGCAA 
CAGCATCGAC AGCAGCAGCA GCAGCAGCAG CAGCAACAAG AATACCATGA ATTGTTCAGG 
CACATGAACC AAGGGGATGC TGTTAGCCTA GCTCCCAGCC TCGGGGGACA GAATATGACA 
GAGCAACAGG CTTTATCTTA TCAAAATGCT GACTCGTACC ACCGCCACCA CACCAGCCCC 
CAGCATATCT TACAGATCAG GGCGCAAGAT TGTATCTCAC AGGGTCCCTC GCCCACCCCC 
ACCCATGGCT ATGCCCATCA GCCACCACTA ATGCATTCGG AGAGTATGGA GGAAGACTGC 
TTGTGTGAGG GGCTCAAGGA GGGCTTCCCA GACAAGAGCT CAAGCACACT GACCAAAGGT 
TGCCACAACA GCCCTCTGCT CTTGTGTACC AGTGGGCCTG GGGACCCTGA GCCTTTGCTG 
GGAACTGTGA GTCAGGCCCG GGAGCTGGGG ATCCATCCCT ACGGACACCA GCCAACTGCC 
ACCACGTTCA GTAGAAATAA GGTGCCCAGC CGAGAGTCTG TCCTAGGGAA CTGCCTGGAA 
AGAAGTTCTC CTGGACAAGC AATGGAGCTG CCGGATCACA ACGGCCTTGG GTACCCAGTA 
CGGCCCTTAG TCAGTGAGCA CCTCAGGTCC CGGACGCTCC AGAGACACCA CACGATCCAG 
AACAGCGACG ATGCCTATGT ACAGCTGGAT ACCTTGCCAG GAATGAGCCT GGTGGCAGGC 
AAGGCGCTGA GCTCTGCCCG GATGTCAGAT GCAGTTCTTA GTCAGTCTTC ACTCATGGGC 
AGCCAACAGT TTCAGGATGA GGAAGATGAA GAATGTGGGG TGAGCCTGGG CCACGAGCAT 
CCAGGCCTGG GTGATGGCAG CCAGCATCTC AACTCCTCTC GCTATCCAGC TACGTGTGTT 
ACAGACATCA TGCTCAGCCA CAAGCACCCA GAGGTCTCCT TCAGCATGGA GCAAGCCGGC 
GTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006510653.1
CDS	34..3999
Translation	MAAAAASGAGGVAVAGAGGAGPAGRLLPPPAAGPPAAPAAVPPAAVPARPTAPASRGSMAARIGYYEIDRTIGKGNFAVVKRATHLVTKAKVAIKIIDKSQLDEENLKKIFREVQIMKMLCHPHIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQLLKTWCGSPPYAAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVLDPNKRLSMEQICRHKWMKLGDADPNFDRLIAECQQLKEERQSDPLNDDVLLAMEDMGLDKERTLQSLRSDAYDHYSAIYSLLCDRHKKHKTLRPGALPSMPQAMTFQAPVNLQAEQTGTAMNLSVPQVQLINPENQIIEPDGAVNLDSDEGEEPSPEALVRYLSMRRHTVGVADPRTEVMEDLQKLLPGFPGVNPQGPFLQVAPNMNFTHNLLPMQSLQPTGQLEYKEQSLLQPPTLQLLNGMGPLGRRASDGGANIQLHAQQLLKRPRGPSPLVTMTPAVPAVTPVDEESSDGEPDQEAVQSSTYKDSNTLHLPTERFSPVRRFSDGAASIQAFKAHLEKMGNSSSIKQLQQECEQLQKMYGGQVDERTLEKTQQQHMLYQQEQHHQILQQQIQDSICPPQPSPPLQVACENQPALLTHQLQRLRIQPSSPPPNHPSNHLFRQPSNSPPPVSSAMITSHGATSPSQFQGLPSHGAIFQQQPENCSPPPSVALTCLGLQQASQSQPVTIQLQEPVDMLSNMAGTAAGSAGRSIPISPSASQIQIQHRASLMAPFSYGHRPLSKQLSADSAEAHSLNMNRFSPANYDQAHLHPHLFSDQSRGSPSSYSPSTGVGFPPTQALKVPPLDQFPTFPPSAQQQPPHYTTSALQQALLSPTPPDYPRHQQVPHILQGLLSPRHSLTGHSDIRLPPAEFAQLIKRQQQHRQQQQQQQQQQEYHELFRHMNQGDAVSLAPSLGGQNMTEQQALSYQNADSYHRHHTSPQHILQIRAQDCISQGPSPTPTHGYAHQPPLMHSESMEEDCLCEGLKEGFPDKSSSTLTKGCHNSPLLLCTSGPGDPEPLLGTVSQARELGIHPYGHQPTATTFSRNKVPSRESVLGNCLERSSPGQAMELPDHNGLGYPVRPLVSEHLRSRTLQRHHTIQNSDDAYVQLDTLPGMSLVAGKALSSARMSDAVLSQSSLMGSQQFQDEEDEECGVSLGHEHPGLGDGSQHLNSSRYPATCVTDIMLSHKHPEVSFSMEQAGV

Target ORF information:

RefSeq Version	XM_006510590.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus SIK family kinase 3 (Sik3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006510590.3

ORF Insert Sequence:

ATGGCGGCGG CGGCGGCGAG CGGAGCTGGC GGGGTTGCCG TGGCCGGAGC AGGGGGAGCC 
GGGCCGGCCG GCCGCCTGCT GCCTCCGCCC GCCGCGGGGC CCCCGGCAGC CCCCGCCGCA 
GTGCCCCCGG CCGCCGTCCC GGCGCGTCCC ACAGCCCCGG CCTCCCGCGG GTCGATGGCC 
GCTCGCATCG GCTACTACGA GATCGACCGC ACCATCGGCA AGGGCAACTT CGCTGTGGTC 
AAGCGGGCCA CGCACCTCGT CACCAAGGCC AAGGTTGCTA TTAAAATCAT AGATAAGAGC 
CAGCTGGATG AAGAAAACTT GAAGAAGATT TTCCGGGAGG TTCAGATAAT GAAGATGCTT 
TGCCATCCAC ACATCATCAG ACTCTACCAG GTCATGGAGA CAGAGCGCAT GATTTACCTG 
GTGACAGAAT ACGCTAGCGG AGGGGAGATA TTTGACCACT TGGTAGCCCA TGGAAGAATG 
GCAGAGAAGG AAGCTCGACG GAAGTTCAAA CAGATCGTCA CAGCGGTGTA TTTTTGTCAC 
TGTCGGAATA TCGTTCATCG TGATTTAAAA GCCGAAAACT TACTTCTGGA CGCCAATCTG 
AATATCAAAA TAGCAGACTT TGGCTTCAGC AACCTCTTCA CTCCAGGGCA GCTGCTGAAG 
ACGTGGTGTG GCAGCCCTCC CTATGCCGCC CCAGAGCTCT TCGAAGGGAA GGAATATGAT 
GGGCCCAAAG TGGACATATG GAGCCTTGGA GTTGTCCTCT ATGTGCTGGT GTGTGGCGCC 
CTGCCGTTTG ATGGGAGCAC ACTGCAGAAT CTGCGGGCCC GCGTGCTGAG TGGCAAGTTC 
CGCATCCCGT TCTTTATGTC CACAGAGTGT GAGCACTTGA TCCGCCACAT GCTGGTGTTA 
GATCCAAATA AGCGCCTCTC AATGGAACAG ATCTGCAGGC ACAAGTGGAT GAAGCTCGGA 
GATGCAGACC CCAACTTTGA CAGGTTAATA GCGGAGTGCC AGCAACTGAA GGAGGAAAGG 
CAGTCGGACC CCCTCAACGA TGATGTCCTC TTGGCTATGG AAGACATGGG GCTGGACAAG 
GAGCGCACAC TTCAGTCATT AAGGTCAGAT GCCTATGACC ACTATAGTGC AATCTACAGC 
CTGCTGTGCG ATCGACACAA GAAACATAAA ACTCTGCGTC CCGGAGCACT TCCCAGCATG 
CCCCAAGCCA TGACTTTCCA GGCACCAGTC AATCTCCAGG CGGAGCAGAC AGGCACTGCT 
ATGAACCTTA GCGTCCCTCA AGTTCAGCTG ATCAACCCAG AGAACCAAAT TATAGAGCCT 
GACGGGGCTG TGAACTTGGA CAGTGATGAG GGTGAAGAGC CTTCTCCAGA AGCCTTGGTT 
CGCTATTTGT CAATGAGGAG GCACACGGTG GGAGTGGCTG ACCCACGCAC GGAAGTTATG 
GAAGATCTGC AGAAGCTGCT GCCTGGCTTT CCTGGAGTAA ACCCACAGGG TCCATTCCTA 
CAAGTGGCCC CTAACATGAA CTTCACGCAC AACCTGTTGC CCATGCAGAG TCTGCAGCCA 
ACTGGGCAGC TTGAGTACAA GGAACAGTCT CTGTTACAGC CGCCTACACT ACAGCTACTG 
AACGGAATGG GGCCCCTTGG CCGGAGAGCC TCAGATGGAG GCGCCAACAT CCAACTGCAT 
GCCCAGCAGC TGCTCAAGCG CCCACGGGGA CCGTCCCCAC TTGTCACCAT GACACCAGCA 
GTGCCAGCAG TTACCCCTGT GGATGAGGAG AGCTCGGATG GGGAGCCAGA TCAGGAAGCT 
GTGCAGAGCT CCACCTACAA GGACTCCAAC ACCCTGCATC TCCCTACGGA GCGTTTCTCC 
CCCGTGCGCC GGTTCTCAGA CGGGGCTGCA AGCATCCAGG CCTTCAAAGC TCACCTGGAA 
AAAATGGGCA ACAGCAGCAG CATCAAGCAG TTGCAGCAGG AGTGTGAGCA GCTGCAGAAG 
ATGTACGGGG GGCAGGTGGA TGAGAGGACC CTGGAGAAGA CCCAGCAGCA GCATATGTTG 
TACCAGCAGG AGCAGCACCA TCAGATCCTC CAGCAGCAAA TCCAAGATTC TATTTGTCCT 
CCTCAGCCCT CCCCACCTCT TCAGGTTGCC TGTGAAAACC AACCAGCCCT CCTCACCCAC 
CAGCTCCAGA GGTTAAGGAT TCAACCTTCA AGCCCACCCC CCAACCATCC CAGCAACCAT 
CTCTTCAGAC AGCCAAGTAA CAGTCCTCCC CCGGTCAGCA GTGCCATGAT CACGTCTCAC 
GGTGCTACGT CTCCCTCCCA GTTTCAAGGC TTACCCTCCC ATGGTGCAAT CTTCCAGCAG 
CAACCCGAGA ACTGTTCCCC GCCTCCCAGT GTAGCACTAA CCTGCCTGGG CCTACAGCAG 
GCTAGCCAGT CACAGCCAGT GACTATCCAG CTACAGGAGC CAGTTGACAT GCTCAGCAAC 
ATGGCCGGAA CCGCGGCAGG CTCTGCAGGG CGGAGCATCC CCATCAGCCC CAGCGCCAGT 
CAGATTCAGA TACAGCACCG AGCCAGCCTA ATGGCTCCCT TCAGCTATGG GCACCGGCCC 
TTGTCCAAGC AGCTGAGCGC TGACAGTGCA GAGGCCCACA GCTTGAACAT GAATCGGTTC 
TCCCCTGCCA ACTACGACCA GGCGCATTTA CACCCCCATC TGTTTTCGGA CCAGTCCCGA 
GGTTCCCCCA GCAGCTACAG CCCTTCAACA GGAGTGGGGT TTCCTCCAAC TCAAGCCCTG 
AAAGTTCCTC CGCTTGACCA GTTCCCCACT TTCCCTCCCA GTGCCCAGCA GCAGCCACCC 
CACTATACCA CGTCAGCACT ACAGCAGGCC CTGCTATCTC CTACACCGCC AGACTATCCC 
CGACACCAGC AGGTTCCCCA TATCCTTCAA GGACTGCTCT CTCCCCGGCA TTCACTCACC 
GGCCACTCGG ACATTCGGCT GCCTCCGGCA GAGTTTGCAC AGCTCATCAA AAGGCAGCAA 
CAGCATCGAC AGCAGCAGCA GCAGCAGCAG CAGCAACAAG AATACCATGA ATTGTTCAGG 
CACATGAACC AAGGGGATGC TGTTAGCCTA GCTCCCAGCC TCGGGGGACA GAATATGACA 
GAGCAACAGG CTTTATCTTA TCAAAATGCT GACTCGTACC ACCGCCACCA CACCAGCCCC 
CAGCATATCT TACAGATCAG GGCGCAAGAT TGTATCTCAC AGGGTCCCTC GCCCACCCCC 
ACCCATGGCT ATGCCCATCA GCCACCACTA ATGCATTCGG AGAGTATGGA GGAAGACTGC 
TTGTGTGAGG GGCTCAAGGA GGGCTTCCCA GACAAGAGCT CAAGCACACT GACCAAAGGT 
TGCCACAACA GCCCTCTGCT CTTGTGTACC AGTGGGCCTG GGGACCCTGA GCCTTTGCTG 
GGAACTGTGA GTCAGGCCCG GGAGCTGGGG ATCCATCCCT ACGGACACCA GCCAACTGCC 
ACCACGTTCA GTAGAAATAA GGTGCCCAGC CGAGAGTCTG TCCTAGGGAA CTGCCTGGAA 
AGAAGTTCTC CTGGACAAGC AATGGAGCTG CCGGATCACA ACGGCCTTGG GTACCCAGTA 
CGGCCCTTAG TCAGTGAGCA CCTCAGGTCC CGGACGCTCC AGAGACACCA CACGATCCAG 
AACAGCGACG ATGCCTATGT ACAGCTGGAT ACCTTGCCAG GAATGAGCCT GGTGGCAGGC 
AAGGCGCTGA GCTCTGCCCG GATGTCAGAT GCAGTTCTTA GTCAGTCTTC ACTCATGGGC 
AGCCAACAGT TTCAGGATGA GGAAGATGAA GAATGTGGGG TGAGCCTGGG CCACGAGCAT 
CCAGGCCTGG GTGATGGCAG CCAGCATCTC AACTCCTCTC GCTATCCAGC TACGTGTGTT 
ACAGACATCA TGCTCAGCCA CAAGCACCCA GAGGTCTCCT TCAGCATGGA GCAAGCCGGC 
GTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Sik3 ( NM_027498.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_081774.3 Mus musculus SIK family kinase 3 (Sik3), mRNA.

Price & Availability↑

CloneID	OMu18881
Clone ID Related Accession (Same CDS sequence)	NM_027498.3
Accession Version	NM_027498.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4110bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Mus musculus(house mouse)
Product	serine/threonine-protein kinase SIK3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CJ171970.1, BC080688.1, AK129257.1 and BG229919.1. On Nov 15, 2007 this sequence version replaced NM_027498.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC063268.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849379 [ECO:0000348] ##Evidence-Data-END##

ATGGCGGCGG CGGCGGCGAG CGGAGCTGGC GGGGTTGCCG TGGCCGGAGC AGGGGGAGCC 
GGGCCGGCCG GCCGCCTGCT GCCTCCGCCC GCCGCGGGGC CCCCGGCAGC CCCCGCCGCA 
GTGCCCCCGG CCGCCGTCCC GGCGCGTCCC ACAGCCCCGG CCTCCCGCGG GTCGATGGCC 
GCTCGCATCG GCTACTACGA GATCGACCGC ACCATCGGCA AGGGCAACTT CGCTGTGGTC 
AAGCGGGCCA CGCACCTCGT CACCAAGGCC AAGGTTGCTA TTAAAATCAT AGATAAGAGC 
CAGCTGGATG AAGAAAACTT GAAGAAGATT TTCCGGGAGG TTCAGATAAT GAAGATGCTT 
TGCCATCCAC ACATCATCAG ACTCTACCAG GTCATGGAGA CAGAGCGCAT GATTTACCTG 
GTGACAGAAT ACGCTAGCGG AGGGGAGATA TTTGACCACT TGGTAGCCCA TGGAAGAATG 
GCAGAGAAGG AAGCTCGACG GAAGTTCAAA CAGATCGTCA CAGCGGTGTA TTTTTGTCAC 
TGTCGGAATA TCGTTCATCG TGATTTAAAA GCCGAAAACT TACTTCTGGA CGCCAATCTG 
AATATCAAAA TAGCAGACTT TGGCTTCAGC AACCTCTTCA CTCCAGGGCA GCTGCTGAAG 
ACGTGGTGTG GCAGCCCTCC CTATGCCGCC CCAGAGCTCT TCGAAGGGAA GGAATATGAT 
GGGCCCAAAG TGGACATATG GAGCCTTGGA GTTGTCCTCT ATGTGCTGGT GTGTGGCGCC 
CTGCCGTTTG ATGGGAGCAC ACTGCAGAAT CTGCGGGCCC GCGTGCTGAG TGGCAAGTTC 
CGCATCCCGT TCTTTATGTC CACAGAGTGT GAGCACTTGA TCCGCCACAT GCTGGTGTTA 
GATCCAAATA AGCGCCTCTC AATGGAACAG ATCTGCAGGC ACAAGTGGAT GAAGCTCGGA 
GATGCAGACC CCAACTTTGA CAGGTTAATA GCGGAGTGCC AGCAACTGAA GGAGGAAAGG 
CAGTCGGACC CCCTCAACGA TGATGTCCTC TTGGCTATGG AAGACATGGG GCTGGACAAG 
GAGCGCACAC TTCAGTCATT AAGGTCAGAT GCCTATGACC ACTATAGTGC AATCTACAGC 
CTGCTGTGCG ATCGACACAA GAAACATAAA ACTCTGCGTC CCGGAGCACT TCCCAGCATG 
CCCCAAGCCA TGACTTTCCA GGCACCAGTC AATCTCCAGG CGGAGCAGAC AGGCACTGCT 
ATGAACCTTA GCGTCCCTCA AGTTCAGCTG ATCAACCCAG AGAACCAAAT TATAGAGCCT 
GACGGGGCTG TGAACTTGGA CAGTGATGAG GGTGAAGAGC CTTCTCCAGA AGCCTTGGTT 
CGCTATTTGT CAATGAGGAG GCACACGGTG GGAGTGGCTG ACCCACGCAC GGAAGTTATG 
GAAGATCTGC AGAAGCTGCT GCCTGGCTTT CCTGGAGTAA ACCCACAGGG TCCATTCCTA 
CAAGTGGCCC CTAACATGAA CTTCACGCAC AACCTGTTGC CCATGCAGAG TCTGCAGCCA 
ACTGGGCAGC TTGAGTACAA GGAACAGTCT CTGTTACAGC CGCCTACACT ACAGCTACTG 
AACGGAATGG GGCCCCTTGG CCGGAGAGCC TCAGATGGAG GCGCCAACAT CCAACTGCAT 
GCCCAGCAGC TGCTCAAGCG CCCACGGGGA CCGTCCCCAC TTGTCACCAT GACACCAGCA 
GTGCCAGCAG TTACCCCTGT GGATGAGGAG AGCTCGGATG GGGAGCCAGA TCAGGAAGCT 
GTGCAGAGGT ACTTGGCAAA TAGGTCCAAA AGGCACACAC TGGCCATGAC CAGCCCGACA 
GCTGAGATCC CACCGGACCT GCAACGGCAG CTAGGACAAC AGTCTTTCCG TTCCCGGGTC 
TGGCCTCCTC ACCTGGTACC TGACCAGCAT CGCTCCACCT ACAAGGACTC CAACACCCTG 
CATCTCCCTA CGGAGCGTTT CTCCCCCGTG CGCCGGTTCT CAGACGGGGC TGCAAGCATC 
CAGGCCTTCA AAGCTCACCT GGAAAAAATG GGCAACAGCA GCAGCATCAA GCAGTTGCAG 
CAGGAGTGTG AGCAGCTGCA GAAGATGTAC GGGGGGCAGG TGGATGAGAG GACCCTGGAG 
AAGACCCAGC AGCAGCATAT GTTGTACCAG CAGGAGCAGC ACCATCAGAT CCTCCAGCAG 
CAAATCCAAG ATTCTATTTG TCCTCCTCAG CCCTCCCCAC CTCTTCAGGT TGCCTGTGAA 
AACCAACCAG CCCTCCTCAC CCACCAGCTC CAGAGGTTAA GGATTCAACC TTCAAGCCCA 
CCCCCCAACC ATCCCAGCAA CCATCTCTTC AGACAGCCAA GTAACAGTCC TCCCCCGGTC 
AGCAGTGCCA TGATCACGTC TCACGGTGCT ACGTCTCCCT CCCAGTTTCA AGGCTTACCC 
TCCCATGGTG CAATCTTCCA GCAGCAACCC GAGAACTGTT CCCCGCCTCC CAGTGTAGCA 
CTAACCTGCC TGGGCCTACA GCAGGCTAGC CAGTCACAGC CAGTGACTAT CCAGCTACAG 
GAGCCAGTTG ACATGCTCAG CAACATGGCC GGAACCGCGG CAGGCTCTGC AGGGCGGAGC 
ATCCCCATCA GCCCCAGCGC CAGTCAGATT CAGATACAGC ACCGAGCCAG CCTAATGGCT 
CCCTTCAGCT ATGGGCACCG GCCCTTGTCC AAGCAGCTGA GCGCTGACAG TGCAGAGGCC 
CACAGCTTGA ACATGAATCG GTTCTCCCCT GCCAACTACG ACCAGGCGCA TTTACACCCC 
CATCTGTTTT CGGACCAGTC CCGAGGTTCC CCCAGCAGCT ACAGCCCTTC AACAGGAGTG 
GGGTTTCCTC CAACTCAAGC CCTGAAAGTT CCTCCGCTTG ACCAGTTCCC CACTTTCCCT 
CCCAGTGCCC AGCAGCAGCC ACCCCACTAT ACCACGTCAG CACTACAGCA GGCCCTGCTA 
TCTCCTACAC CGCCAGACTA TCCCCGACAC CAGCAGGTTC CCCATATCCT TCAAGGACTG 
CTCTCTCCCC GGCATTCACT CACCGGCCAC TCGGACATTC GGCTGCCTCC GGCAGAGTTT 
GCACAGCTCA TCAAAAGGCA GCAACAGCAT CGACAGCAGC AGCAGCAGCA GCAGCAGCAA 
CAAGAATACC ATGAATTGTT CAGGCACATG AACCAAGGGG ATGCTGTTAG CCTAGCTCCC 
AGCCTCGGGG GACAGAATAT GACAGAGCAA CAGGCTTTAT CTTATCAAAA TGCTGACTCG 
TACCACCGCC ACCACACCAG CCCCCAGCAT ATCTTACAGA TCAGGGCGCA AGATTGTATC 
TCACAGGGTC CCTCGCCCAC CCCCACCCAT GGCTATGCCC ATCAGCCACC ACTAATGCAT 
TCGGAGAGTA TGGAGGAAGA CTGCTTGTGT GAGGGGCTCA AGGAGGGCTT CCCAGACAAG 
AGCTCAAGCA CACTGACCAA AGGTTGCCAC AACAGCCCTC TGCTCTTGTG TACCAGTGGG 
CCTGGGGACC CTGAGCCTTT GCTGGGAACT GTGAGTCAGG CCCGGGAGCT GGGGATCCAT 
CCCTACGGAC ACCAGCCAAC TGCCACCACG TTCAGTAGAA ATAAGGTGCC CAGCCGAGAG 
TCTGTCCTAG GGAACTGCCT GGAAAGAAGT TCTCCTGGAC AAGCAATGGA GCTGCCGGAT 
CACAACGGCC TTGGGTACCC AGTACGGCCC TTAGTCAGTG AGCACCTCAG GTCCCGGACG 
CTCCAGAGAC ACCACACGAT CCAGAACAGC GACGATGCCT ATGTACAGCT GGATACCTTG 
CCAGGAATGA GCCTGGTGGC AGGCAAGGCG CTGAGCTCTG CCCGGATGTC AGATGCAGTT 
CTTAGTCAGT CTTCACTCAT GGGCAGCCAA CAGTTTCAGG ATGAGGAAGA TGAAGAATGT 
GGGGTGAGCC TGGGCCACGA GCATCCAGGC CTGGGTGATG GCAGCCAGCA TCTCAACTCC 
TCTCGCTATC CAGCTACGTG TGTTACAGAC ATCATGCTCA GCCACAAGCA CCCAGAGGTC 
TCCTTCAGCA TGGAGCAAGC CGGCGTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_081774.3
CDS	39..4148
Translation	MAAAAASGAGGVAVAGAGGAGPAGRLLPPPAAGPPAAPAAVPPAAVPARPTAPASRGSMAARIGYYEIDRTIGKGNFAVVKRATHLVTKAKVAIKIIDKSQLDEENLKKIFREVQIMKMLCHPHIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQLLKTWCGSPPYAAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVLDPNKRLSMEQICRHKWMKLGDADPNFDRLIAECQQLKEERQSDPLNDDVLLAMEDMGLDKERTLQSLRSDAYDHYSAIYSLLCDRHKKHKTLRPGALPSMPQAMTFQAPVNLQAEQTGTAMNLSVPQVQLINPENQIIEPDGAVNLDSDEGEEPSPEALVRYLSMRRHTVGVADPRTEVMEDLQKLLPGFPGVNPQGPFLQVAPNMNFTHNLLPMQSLQPTGQLEYKEQSLLQPPTLQLLNGMGPLGRRASDGGANIQLHAQQLLKRPRGPSPLVTMTPAVPAVTPVDEESSDGEPDQEAVQRYLANRSKRHTLAMTSPTAEIPPDLQRQLGQQSFRSRVWPPHLVPDQHRSTYKDSNTLHLPTERFSPVRRFSDGAASIQAFKAHLEKMGNSSSIKQLQQECEQLQKMYGGQVDERTLEKTQQQHMLYQQEQHHQILQQQIQDSICPPQPSPPLQVACENQPALLTHQLQRLRIQPSSPPPNHPSNHLFRQPSNSPPPVSSAMITSHGATSPSQFQGLPSHGAIFQQQPENCSPPPSVALTCLGLQQASQSQPVTIQLQEPVDMLSNMAGTAAGSAGRSIPISPSASQIQIQHRASLMAPFSYGHRPLSKQLSADSAEAHSLNMNRFSPANYDQAHLHPHLFSDQSRGSPSSYSPSTGVGFPPTQALKVPPLDQFPTFPPSAQQQPPHYTTSALQQALLSPTPPDYPRHQQVPHILQGLLSPRHSLTGHSDIRLPPAEFAQLIKRQQQHRQQQQQQQQQQEYHELFRHMNQGDAVSLAPSLGGQNMTEQQALSYQNADSYHRHHTSPQHILQIRAQDCISQGPSPTPTHGYAHQPPLMHSESMEEDCLCEGLKEGFPDKSSSTLTKGCHNSPLLLCTSGPGDPEPLLGTVSQARELGIHPYGHQPTATTFSRNKVPSRESVLGNCLERSSPGQAMELPDHNGLGYPVRPLVSEHLRSRTLQRHHTIQNSDDAYVQLDTLPGMSLVAGKALSSARMSDAVLSQSSLMGSQQFQDEEDEECGVSLGHEHPGLGDGSQHLNSSRYPATCVTDIMLSHKHPEVSFSMEQAGV

Target ORF information:

RefSeq Version	NM_027498.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus SIK family kinase 3 (Sik3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_027498.3

ORF Insert Sequence:

ATGGCGGCGG CGGCGGCGAG CGGAGCTGGC GGGGTTGCCG TGGCCGGAGC AGGGGGAGCC 
GGGCCGGCCG GCCGCCTGCT GCCTCCGCCC GCCGCGGGGC CCCCGGCAGC CCCCGCCGCA 
GTGCCCCCGG CCGCCGTCCC GGCGCGTCCC ACAGCCCCGG CCTCCCGCGG GTCGATGGCC 
GCTCGCATCG GCTACTACGA GATCGACCGC ACCATCGGCA AGGGCAACTT CGCTGTGGTC 
AAGCGGGCCA CGCACCTCGT CACCAAGGCC AAGGTTGCTA TTAAAATCAT AGATAAGAGC 
CAGCTGGATG AAGAAAACTT GAAGAAGATT TTCCGGGAGG TTCAGATAAT GAAGATGCTT 
TGCCATCCAC ACATCATCAG ACTCTACCAG GTCATGGAGA CAGAGCGCAT GATTTACCTG 
GTGACAGAAT ACGCTAGCGG AGGGGAGATA TTTGACCACT TGGTAGCCCA TGGAAGAATG 
GCAGAGAAGG AAGCTCGACG GAAGTTCAAA CAGATCGTCA CAGCGGTGTA TTTTTGTCAC 
TGTCGGAATA TCGTTCATCG TGATTTAAAA GCCGAAAACT TACTTCTGGA CGCCAATCTG 
AATATCAAAA TAGCAGACTT TGGCTTCAGC AACCTCTTCA CTCCAGGGCA GCTGCTGAAG 
ACGTGGTGTG GCAGCCCTCC CTATGCCGCC CCAGAGCTCT TCGAAGGGAA GGAATATGAT 
GGGCCCAAAG TGGACATATG GAGCCTTGGA GTTGTCCTCT ATGTGCTGGT GTGTGGCGCC 
CTGCCGTTTG ATGGGAGCAC ACTGCAGAAT CTGCGGGCCC GCGTGCTGAG TGGCAAGTTC 
CGCATCCCGT TCTTTATGTC CACAGAGTGT GAGCACTTGA TCCGCCACAT GCTGGTGTTA 
GATCCAAATA AGCGCCTCTC AATGGAACAG ATCTGCAGGC ACAAGTGGAT GAAGCTCGGA 
GATGCAGACC CCAACTTTGA CAGGTTAATA GCGGAGTGCC AGCAACTGAA GGAGGAAAGG 
CAGTCGGACC CCCTCAACGA TGATGTCCTC TTGGCTATGG AAGACATGGG GCTGGACAAG 
GAGCGCACAC TTCAGTCATT AAGGTCAGAT GCCTATGACC ACTATAGTGC AATCTACAGC 
CTGCTGTGCG ATCGACACAA GAAACATAAA ACTCTGCGTC CCGGAGCACT TCCCAGCATG 
CCCCAAGCCA TGACTTTCCA GGCACCAGTC AATCTCCAGG CGGAGCAGAC AGGCACTGCT 
ATGAACCTTA GCGTCCCTCA AGTTCAGCTG ATCAACCCAG AGAACCAAAT TATAGAGCCT 
GACGGGGCTG TGAACTTGGA CAGTGATGAG GGTGAAGAGC CTTCTCCAGA AGCCTTGGTT 
CGCTATTTGT CAATGAGGAG GCACACGGTG GGAGTGGCTG ACCCACGCAC GGAAGTTATG 
GAAGATCTGC AGAAGCTGCT GCCTGGCTTT CCTGGAGTAA ACCCACAGGG TCCATTCCTA 
CAAGTGGCCC CTAACATGAA CTTCACGCAC AACCTGTTGC CCATGCAGAG TCTGCAGCCA 
ACTGGGCAGC TTGAGTACAA GGAACAGTCT CTGTTACAGC CGCCTACACT ACAGCTACTG 
AACGGAATGG GGCCCCTTGG CCGGAGAGCC TCAGATGGAG GCGCCAACAT CCAACTGCAT 
GCCCAGCAGC TGCTCAAGCG CCCACGGGGA CCGTCCCCAC TTGTCACCAT GACACCAGCA 
GTGCCAGCAG TTACCCCTGT GGATGAGGAG AGCTCGGATG GGGAGCCAGA TCAGGAAGCT 
GTGCAGAGGT ACTTGGCAAA TAGGTCCAAA AGGCACACAC TGGCCATGAC CAGCCCGACA 
GCTGAGATCC CACCGGACCT GCAACGGCAG CTAGGACAAC AGTCTTTCCG TTCCCGGGTC 
TGGCCTCCTC ACCTGGTACC TGACCAGCAT CGCTCCACCT ACAAGGACTC CAACACCCTG 
CATCTCCCTA CGGAGCGTTT CTCCCCCGTG CGCCGGTTCT CAGACGGGGC TGCAAGCATC 
CAGGCCTTCA AAGCTCACCT GGAAAAAATG GGCAACAGCA GCAGCATCAA GCAGTTGCAG 
CAGGAGTGTG AGCAGCTGCA GAAGATGTAC GGGGGGCAGG TGGATGAGAG GACCCTGGAG 
AAGACCCAGC AGCAGCATAT GTTGTACCAG CAGGAGCAGC ACCATCAGAT CCTCCAGCAG 
CAAATCCAAG ATTCTATTTG TCCTCCTCAG CCCTCCCCAC CTCTTCAGGT TGCCTGTGAA 
AACCAACCAG CCCTCCTCAC CCACCAGCTC CAGAGGTTAA GGATTCAACC TTCAAGCCCA 
CCCCCCAACC ATCCCAGCAA CCATCTCTTC AGACAGCCAA GTAACAGTCC TCCCCCGGTC 
AGCAGTGCCA TGATCACGTC TCACGGTGCT ACGTCTCCCT CCCAGTTTCA AGGCTTACCC 
TCCCATGGTG CAATCTTCCA GCAGCAACCC GAGAACTGTT CCCCGCCTCC CAGTGTAGCA 
CTAACCTGCC TGGGCCTACA GCAGGCTAGC CAGTCACAGC CAGTGACTAT CCAGCTACAG 
GAGCCAGTTG ACATGCTCAG CAACATGGCC GGAACCGCGG CAGGCTCTGC AGGGCGGAGC 
ATCCCCATCA GCCCCAGCGC CAGTCAGATT CAGATACAGC ACCGAGCCAG CCTAATGGCT 
CCCTTCAGCT ATGGGCACCG GCCCTTGTCC AAGCAGCTGA GCGCTGACAG TGCAGAGGCC 
CACAGCTTGA ACATGAATCG GTTCTCCCCT GCCAACTACG ACCAGGCGCA TTTACACCCC 
CATCTGTTTT CGGACCAGTC CCGAGGTTCC CCCAGCAGCT ACAGCCCTTC AACAGGAGTG 
GGGTTTCCTC CAACTCAAGC CCTGAAAGTT CCTCCGCTTG ACCAGTTCCC CACTTTCCCT 
CCCAGTGCCC AGCAGCAGCC ACCCCACTAT ACCACGTCAG CACTACAGCA GGCCCTGCTA 
TCTCCTACAC CGCCAGACTA TCCCCGACAC CAGCAGGTTC CCCATATCCT TCAAGGACTG 
CTCTCTCCCC GGCATTCACT CACCGGCCAC TCGGACATTC GGCTGCCTCC GGCAGAGTTT 
GCACAGCTCA TCAAAAGGCA GCAACAGCAT CGACAGCAGC AGCAGCAGCA GCAGCAGCAA 
CAAGAATACC ATGAATTGTT CAGGCACATG AACCAAGGGG ATGCTGTTAG CCTAGCTCCC 
AGCCTCGGGG GACAGAATAT GACAGAGCAA CAGGCTTTAT CTTATCAAAA TGCTGACTCG 
TACCACCGCC ACCACACCAG CCCCCAGCAT ATCTTACAGA TCAGGGCGCA AGATTGTATC 
TCACAGGGTC CCTCGCCCAC CCCCACCCAT GGCTATGCCC ATCAGCCACC ACTAATGCAT 
TCGGAGAGTA TGGAGGAAGA CTGCTTGTGT GAGGGGCTCA AGGAGGGCTT CCCAGACAAG 
AGCTCAAGCA CACTGACCAA AGGTTGCCAC AACAGCCCTC TGCTCTTGTG TACCAGTGGG 
CCTGGGGACC CTGAGCCTTT GCTGGGAACT GTGAGTCAGG CCCGGGAGCT GGGGATCCAT 
CCCTACGGAC ACCAGCCAAC TGCCACCACG TTCAGTAGAA ATAAGGTGCC CAGCCGAGAG 
TCTGTCCTAG GGAACTGCCT GGAAAGAAGT TCTCCTGGAC AAGCAATGGA GCTGCCGGAT 
CACAACGGCC TTGGGTACCC AGTACGGCCC TTAGTCAGTG AGCACCTCAG GTCCCGGACG 
CTCCAGAGAC ACCACACGAT CCAGAACAGC GACGATGCCT ATGTACAGCT GGATACCTTG 
CCAGGAATGA GCCTGGTGGC AGGCAAGGCG CTGAGCTCTG CCCGGATGTC AGATGCAGTT 
CTTAGTCAGT CTTCACTCAT GGGCAGCCAA CAGTTTCAGG ATGAGGAAGA TGAAGAATGT 
GGGGTGAGCC TGGGCCACGA GCATCCAGGC CTGGGTGATG GCAGCCAGCA TCTCAACTCC 
TCTCGCTATC CAGCTACGTG TGTTACAGAC ATCATGCTCA GCCACAAGCA CCCAGAGGTC 
TCCTTCAGCA TGGAGCAAGC CGGCGTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Sik3 ( XM_006510590.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006510653.1 Mus musculus SIK family kinase 3 (Sik3), transcript variant X1, mRNA.

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CloneID	OMu42388
Clone ID Related Accession (Same CDS sequence)	XM_006510590.3 , XM_006510590.2
Accession Version	XM_006510590.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3966bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	serine/threonine-protein kinase SIK3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000075.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006510590.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGCGG CGGCGGCGAG CGGAGCTGGC GGGGTTGCCG TGGCCGGAGC AGGGGGAGCC 
GGGCCGGCCG GCCGCCTGCT GCCTCCGCCC GCCGCGGGGC CCCCGGCAGC CCCCGCCGCA 
GTGCCCCCGG CCGCCGTCCC GGCGCGTCCC ACAGCCCCGG CCTCCCGCGG GTCGATGGCC 
GCTCGCATCG GCTACTACGA GATCGACCGC ACCATCGGCA AGGGCAACTT CGCTGTGGTC 
AAGCGGGCCA CGCACCTCGT CACCAAGGCC AAGGTTGCTA TTAAAATCAT AGATAAGAGC 
CAGCTGGATG AAGAAAACTT GAAGAAGATT TTCCGGGAGG TTCAGATAAT GAAGATGCTT 
TGCCATCCAC ACATCATCAG ACTCTACCAG GTCATGGAGA CAGAGCGCAT GATTTACCTG 
GTGACAGAAT ACGCTAGCGG AGGGGAGATA TTTGACCACT TGGTAGCCCA TGGAAGAATG 
GCAGAGAAGG AAGCTCGACG GAAGTTCAAA CAGATCGTCA CAGCGGTGTA TTTTTGTCAC 
TGTCGGAATA TCGTTCATCG TGATTTAAAA GCCGAAAACT TACTTCTGGA CGCCAATCTG 
AATATCAAAA TAGCAGACTT TGGCTTCAGC AACCTCTTCA CTCCAGGGCA GCTGCTGAAG 
ACGTGGTGTG GCAGCCCTCC CTATGCCGCC CCAGAGCTCT TCGAAGGGAA GGAATATGAT 
GGGCCCAAAG TGGACATATG GAGCCTTGGA GTTGTCCTCT ATGTGCTGGT GTGTGGCGCC 
CTGCCGTTTG ATGGGAGCAC ACTGCAGAAT CTGCGGGCCC GCGTGCTGAG TGGCAAGTTC 
CGCATCCCGT TCTTTATGTC CACAGAGTGT GAGCACTTGA TCCGCCACAT GCTGGTGTTA 
GATCCAAATA AGCGCCTCTC AATGGAACAG ATCTGCAGGC ACAAGTGGAT GAAGCTCGGA 
GATGCAGACC CCAACTTTGA CAGGTTAATA GCGGAGTGCC AGCAACTGAA GGAGGAAAGG 
CAGTCGGACC CCCTCAACGA TGATGTCCTC TTGGCTATGG AAGACATGGG GCTGGACAAG 
GAGCGCACAC TTCAGTCATT AAGGTCAGAT GCCTATGACC ACTATAGTGC AATCTACAGC 
CTGCTGTGCG ATCGACACAA GAAACATAAA ACTCTGCGTC CCGGAGCACT TCCCAGCATG 
CCCCAAGCCA TGACTTTCCA GGCACCAGTC AATCTCCAGG CGGAGCAGAC AGGCACTGCT 
ATGAACCTTA GCGTCCCTCA AGTTCAGCTG ATCAACCCAG AGAACCAAAT TATAGAGCCT 
GACGGGGCTG TGAACTTGGA CAGTGATGAG GGTGAAGAGC CTTCTCCAGA AGCCTTGGTT 
CGCTATTTGT CAATGAGGAG GCACACGGTG GGAGTGGCTG ACCCACGCAC GGAAGTTATG 
GAAGATCTGC AGAAGCTGCT GCCTGGCTTT CCTGGAGTAA ACCCACAGGG TCCATTCCTA 
CAAGTGGCCC CTAACATGAA CTTCACGCAC AACCTGTTGC CCATGCAGAG TCTGCAGCCA 
ACTGGGCAGC TTGAGTACAA GGAACAGTCT CTGTTACAGC CGCCTACACT ACAGCTACTG 
AACGGAATGG GGCCCCTTGG CCGGAGAGCC TCAGATGGAG GCGCCAACAT CCAACTGCAT 
GCCCAGCAGC TGCTCAAGCG CCCACGGGGA CCGTCCCCAC TTGTCACCAT GACACCAGCA 
GTGCCAGCAG TTACCCCTGT GGATGAGGAG AGCTCGGATG GGGAGCCAGA TCAGGAAGCT 
GTGCAGAGCT CCACCTACAA GGACTCCAAC ACCCTGCATC TCCCTACGGA GCGTTTCTCC 
CCCGTGCGCC GGTTCTCAGA CGGGGCTGCA AGCATCCAGG CCTTCAAAGC TCACCTGGAA 
AAAATGGGCA ACAGCAGCAG CATCAAGCAG TTGCAGCAGG AGTGTGAGCA GCTGCAGAAG 
ATGTACGGGG GGCAGGTGGA TGAGAGGACC CTGGAGAAGA CCCAGCAGCA GCATATGTTG 
TACCAGCAGG AGCAGCACCA TCAGATCCTC CAGCAGCAAA TCCAAGATTC TATTTGTCCT 
CCTCAGCCCT CCCCACCTCT TCAGGTTGCC TGTGAAAACC AACCAGCCCT CCTCACCCAC 
CAGCTCCAGA GGTTAAGGAT TCAACCTTCA AGCCCACCCC CCAACCATCC CAGCAACCAT 
CTCTTCAGAC AGCCAAGTAA CAGTCCTCCC CCGGTCAGCA GTGCCATGAT CACGTCTCAC 
GGTGCTACGT CTCCCTCCCA GTTTCAAGGC TTACCCTCCC ATGGTGCAAT CTTCCAGCAG 
CAACCCGAGA ACTGTTCCCC GCCTCCCAGT GTAGCACTAA CCTGCCTGGG CCTACAGCAG 
GCTAGCCAGT CACAGCCAGT GACTATCCAG CTACAGGAGC CAGTTGACAT GCTCAGCAAC 
ATGGCCGGAA CCGCGGCAGG CTCTGCAGGG CGGAGCATCC CCATCAGCCC CAGCGCCAGT 
CAGATTCAGA TACAGCACCG AGCCAGCCTA ATGGCTCCCT TCAGCTATGG GCACCGGCCC 
TTGTCCAAGC AGCTGAGCGC TGACAGTGCA GAGGCCCACA GCTTGAACAT GAATCGGTTC 
TCCCCTGCCA ACTACGACCA GGCGCATTTA CACCCCCATC TGTTTTCGGA CCAGTCCCGA 
GGTTCCCCCA GCAGCTACAG CCCTTCAACA GGAGTGGGGT TTCCTCCAAC TCAAGCCCTG 
AAAGTTCCTC CGCTTGACCA GTTCCCCACT TTCCCTCCCA GTGCCCAGCA GCAGCCACCC 
CACTATACCA CGTCAGCACT ACAGCAGGCC CTGCTATCTC CTACACCGCC AGACTATCCC 
CGACACCAGC AGGTTCCCCA TATCCTTCAA GGACTGCTCT CTCCCCGGCA TTCACTCACC 
GGCCACTCGG ACATTCGGCT GCCTCCGGCA GAGTTTGCAC AGCTCATCAA AAGGCAGCAA 
CAGCATCGAC AGCAGCAGCA GCAGCAGCAG CAGCAACAAG AATACCATGA ATTGTTCAGG 
CACATGAACC AAGGGGATGC TGTTAGCCTA GCTCCCAGCC TCGGGGGACA GAATATGACA 
GAGCAACAGG CTTTATCTTA TCAAAATGCT GACTCGTACC ACCGCCACCA CACCAGCCCC 
CAGCATATCT TACAGATCAG GGCGCAAGAT TGTATCTCAC AGGGTCCCTC GCCCACCCCC 
ACCCATGGCT ATGCCCATCA GCCACCACTA ATGCATTCGG AGAGTATGGA GGAAGACTGC 
TTGTGTGAGG GGCTCAAGGA GGGCTTCCCA GACAAGAGCT CAAGCACACT GACCAAAGGT 
TGCCACAACA GCCCTCTGCT CTTGTGTACC AGTGGGCCTG GGGACCCTGA GCCTTTGCTG 
GGAACTGTGA GTCAGGCCCG GGAGCTGGGG ATCCATCCCT ACGGACACCA GCCAACTGCC 
ACCACGTTCA GTAGAAATAA GGTGCCCAGC CGAGAGTCTG TCCTAGGGAA CTGCCTGGAA 
AGAAGTTCTC CTGGACAAGC AATGGAGCTG CCGGATCACA ACGGCCTTGG GTACCCAGTA 
CGGCCCTTAG TCAGTGAGCA CCTCAGGTCC CGGACGCTCC AGAGACACCA CACGATCCAG 
AACAGCGACG ATGCCTATGT ACAGCTGGAT ACCTTGCCAG GAATGAGCCT GGTGGCAGGC 
AAGGCGCTGA GCTCTGCCCG GATGTCAGAT GCAGTTCTTA GTCAGTCTTC ACTCATGGGC 
AGCCAACAGT TTCAGGATGA GGAAGATGAA GAATGTGGGG TGAGCCTGGG CCACGAGCAT 
CCAGGCCTGG GTGATGGCAG CCAGCATCTC AACTCCTCTC GCTATCCAGC TACGTGTGTT 
ACAGACATCA TGCTCAGCCA CAAGCACCCA GAGGTCTCCT TCAGCATGGA GCAAGCCGGC 
GTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006510653.1
CDS	1..3966
Translation	MAAAAASGAGGVAVAGAGGAGPAGRLLPPPAAGPPAAPAAVPPAAVPARPTAPASRGSMAARIGYYEIDRTIGKGNFAVVKRATHLVTKAKVAIKIIDKSQLDEENLKKIFREVQIMKMLCHPHIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQLLKTWCGSPPYAAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVLDPNKRLSMEQICRHKWMKLGDADPNFDRLIAECQQLKEERQSDPLNDDVLLAMEDMGLDKERTLQSLRSDAYDHYSAIYSLLCDRHKKHKTLRPGALPSMPQAMTFQAPVNLQAEQTGTAMNLSVPQVQLINPENQIIEPDGAVNLDSDEGEEPSPEALVRYLSMRRHTVGVADPRTEVMEDLQKLLPGFPGVNPQGPFLQVAPNMNFTHNLLPMQSLQPTGQLEYKEQSLLQPPTLQLLNGMGPLGRRASDGGANIQLHAQQLLKRPRGPSPLVTMTPAVPAVTPVDEESSDGEPDQEAVQSSTYKDSNTLHLPTERFSPVRRFSDGAASIQAFKAHLEKMGNSSSIKQLQQECEQLQKMYGGQVDERTLEKTQQQHMLYQQEQHHQILQQQIQDSICPPQPSPPLQVACENQPALLTHQLQRLRIQPSSPPPNHPSNHLFRQPSNSPPPVSSAMITSHGATSPSQFQGLPSHGAIFQQQPENCSPPPSVALTCLGLQQASQSQPVTIQLQEPVDMLSNMAGTAAGSAGRSIPISPSASQIQIQHRASLMAPFSYGHRPLSKQLSADSAEAHSLNMNRFSPANYDQAHLHPHLFSDQSRGSPSSYSPSTGVGFPPTQALKVPPLDQFPTFPPSAQQQPPHYTTSALQQALLSPTPPDYPRHQQVPHILQGLLSPRHSLTGHSDIRLPPAEFAQLIKRQQQHRQQQQQQQQQQEYHELFRHMNQGDAVSLAPSLGGQNMTEQQALSYQNADSYHRHHTSPQHILQIRAQDCISQGPSPTPTHGYAHQPPLMHSESMEEDCLCEGLKEGFPDKSSSTLTKGCHNSPLLLCTSGPGDPEPLLGTVSQARELGIHPYGHQPTATTFSRNKVPSRESVLGNCLERSSPGQAMELPDHNGLGYPVRPLVSEHLRSRTLQRHHTIQNSDDAYVQLDTLPGMSLVAGKALSSARMSDAVLSQSSLMGSQQFQDEEDEECGVSLGHEHPGLGDGSQHLNSSRYPATCVTDIMLSHKHPEVSFSMEQAGV

Target ORF information:

RefSeq Version	XM_006510590.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus SIK family kinase 3 (Sik3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006510590.2

ORF Insert Sequence:

ATGGCGGCGG CGGCGGCGAG CGGAGCTGGC GGGGTTGCCG TGGCCGGAGC AGGGGGAGCC 
GGGCCGGCCG GCCGCCTGCT GCCTCCGCCC GCCGCGGGGC CCCCGGCAGC CCCCGCCGCA 
GTGCCCCCGG CCGCCGTCCC GGCGCGTCCC ACAGCCCCGG CCTCCCGCGG GTCGATGGCC 
GCTCGCATCG GCTACTACGA GATCGACCGC ACCATCGGCA AGGGCAACTT CGCTGTGGTC 
AAGCGGGCCA CGCACCTCGT CACCAAGGCC AAGGTTGCTA TTAAAATCAT AGATAAGAGC 
CAGCTGGATG AAGAAAACTT GAAGAAGATT TTCCGGGAGG TTCAGATAAT GAAGATGCTT 
TGCCATCCAC ACATCATCAG ACTCTACCAG GTCATGGAGA CAGAGCGCAT GATTTACCTG 
GTGACAGAAT ACGCTAGCGG AGGGGAGATA TTTGACCACT TGGTAGCCCA TGGAAGAATG 
GCAGAGAAGG AAGCTCGACG GAAGTTCAAA CAGATCGTCA CAGCGGTGTA TTTTTGTCAC 
TGTCGGAATA TCGTTCATCG TGATTTAAAA GCCGAAAACT TACTTCTGGA CGCCAATCTG 
AATATCAAAA TAGCAGACTT TGGCTTCAGC AACCTCTTCA CTCCAGGGCA GCTGCTGAAG 
ACGTGGTGTG GCAGCCCTCC CTATGCCGCC CCAGAGCTCT TCGAAGGGAA GGAATATGAT 
GGGCCCAAAG TGGACATATG GAGCCTTGGA GTTGTCCTCT ATGTGCTGGT GTGTGGCGCC 
CTGCCGTTTG ATGGGAGCAC ACTGCAGAAT CTGCGGGCCC GCGTGCTGAG TGGCAAGTTC 
CGCATCCCGT TCTTTATGTC CACAGAGTGT GAGCACTTGA TCCGCCACAT GCTGGTGTTA 
GATCCAAATA AGCGCCTCTC AATGGAACAG ATCTGCAGGC ACAAGTGGAT GAAGCTCGGA 
GATGCAGACC CCAACTTTGA CAGGTTAATA GCGGAGTGCC AGCAACTGAA GGAGGAAAGG 
CAGTCGGACC CCCTCAACGA TGATGTCCTC TTGGCTATGG AAGACATGGG GCTGGACAAG 
GAGCGCACAC TTCAGTCATT AAGGTCAGAT GCCTATGACC ACTATAGTGC AATCTACAGC 
CTGCTGTGCG ATCGACACAA GAAACATAAA ACTCTGCGTC CCGGAGCACT TCCCAGCATG 
CCCCAAGCCA TGACTTTCCA GGCACCAGTC AATCTCCAGG CGGAGCAGAC AGGCACTGCT 
ATGAACCTTA GCGTCCCTCA AGTTCAGCTG ATCAACCCAG AGAACCAAAT TATAGAGCCT 
GACGGGGCTG TGAACTTGGA CAGTGATGAG GGTGAAGAGC CTTCTCCAGA AGCCTTGGTT 
CGCTATTTGT CAATGAGGAG GCACACGGTG GGAGTGGCTG ACCCACGCAC GGAAGTTATG 
GAAGATCTGC AGAAGCTGCT GCCTGGCTTT CCTGGAGTAA ACCCACAGGG TCCATTCCTA 
CAAGTGGCCC CTAACATGAA CTTCACGCAC AACCTGTTGC CCATGCAGAG TCTGCAGCCA 
ACTGGGCAGC TTGAGTACAA GGAACAGTCT CTGTTACAGC CGCCTACACT ACAGCTACTG 
AACGGAATGG GGCCCCTTGG CCGGAGAGCC TCAGATGGAG GCGCCAACAT CCAACTGCAT 
GCCCAGCAGC TGCTCAAGCG CCCACGGGGA CCGTCCCCAC TTGTCACCAT GACACCAGCA 
GTGCCAGCAG TTACCCCTGT GGATGAGGAG AGCTCGGATG GGGAGCCAGA TCAGGAAGCT 
GTGCAGAGCT CCACCTACAA GGACTCCAAC ACCCTGCATC TCCCTACGGA GCGTTTCTCC 
CCCGTGCGCC GGTTCTCAGA CGGGGCTGCA AGCATCCAGG CCTTCAAAGC TCACCTGGAA 
AAAATGGGCA ACAGCAGCAG CATCAAGCAG TTGCAGCAGG AGTGTGAGCA GCTGCAGAAG 
ATGTACGGGG GGCAGGTGGA TGAGAGGACC CTGGAGAAGA CCCAGCAGCA GCATATGTTG 
TACCAGCAGG AGCAGCACCA TCAGATCCTC CAGCAGCAAA TCCAAGATTC TATTTGTCCT 
CCTCAGCCCT CCCCACCTCT TCAGGTTGCC TGTGAAAACC AACCAGCCCT CCTCACCCAC 
CAGCTCCAGA GGTTAAGGAT TCAACCTTCA AGCCCACCCC CCAACCATCC CAGCAACCAT 
CTCTTCAGAC AGCCAAGTAA CAGTCCTCCC CCGGTCAGCA GTGCCATGAT CACGTCTCAC 
GGTGCTACGT CTCCCTCCCA GTTTCAAGGC TTACCCTCCC ATGGTGCAAT CTTCCAGCAG 
CAACCCGAGA ACTGTTCCCC GCCTCCCAGT GTAGCACTAA CCTGCCTGGG CCTACAGCAG 
GCTAGCCAGT CACAGCCAGT GACTATCCAG CTACAGGAGC CAGTTGACAT GCTCAGCAAC 
ATGGCCGGAA CCGCGGCAGG CTCTGCAGGG CGGAGCATCC CCATCAGCCC CAGCGCCAGT 
CAGATTCAGA TACAGCACCG AGCCAGCCTA ATGGCTCCCT TCAGCTATGG GCACCGGCCC 
TTGTCCAAGC AGCTGAGCGC TGACAGTGCA GAGGCCCACA GCTTGAACAT GAATCGGTTC 
TCCCCTGCCA ACTACGACCA GGCGCATTTA CACCCCCATC TGTTTTCGGA CCAGTCCCGA 
GGTTCCCCCA GCAGCTACAG CCCTTCAACA GGAGTGGGGT TTCCTCCAAC TCAAGCCCTG 
AAAGTTCCTC CGCTTGACCA GTTCCCCACT TTCCCTCCCA GTGCCCAGCA GCAGCCACCC 
CACTATACCA CGTCAGCACT ACAGCAGGCC CTGCTATCTC CTACACCGCC AGACTATCCC 
CGACACCAGC AGGTTCCCCA TATCCTTCAA GGACTGCTCT CTCCCCGGCA TTCACTCACC 
GGCCACTCGG ACATTCGGCT GCCTCCGGCA GAGTTTGCAC AGCTCATCAA AAGGCAGCAA 
CAGCATCGAC AGCAGCAGCA GCAGCAGCAG CAGCAACAAG AATACCATGA ATTGTTCAGG 
CACATGAACC AAGGGGATGC TGTTAGCCTA GCTCCCAGCC TCGGGGGACA GAATATGACA 
GAGCAACAGG CTTTATCTTA TCAAAATGCT GACTCGTACC ACCGCCACCA CACCAGCCCC 
CAGCATATCT TACAGATCAG GGCGCAAGAT TGTATCTCAC AGGGTCCCTC GCCCACCCCC 
ACCCATGGCT ATGCCCATCA GCCACCACTA ATGCATTCGG AGAGTATGGA GGAAGACTGC 
TTGTGTGAGG GGCTCAAGGA GGGCTTCCCA GACAAGAGCT CAAGCACACT GACCAAAGGT 
TGCCACAACA GCCCTCTGCT CTTGTGTACC AGTGGGCCTG GGGACCCTGA GCCTTTGCTG 
GGAACTGTGA GTCAGGCCCG GGAGCTGGGG ATCCATCCCT ACGGACACCA GCCAACTGCC 
ACCACGTTCA GTAGAAATAA GGTGCCCAGC CGAGAGTCTG TCCTAGGGAA CTGCCTGGAA 
AGAAGTTCTC CTGGACAAGC AATGGAGCTG CCGGATCACA ACGGCCTTGG GTACCCAGTA 
CGGCCCTTAG TCAGTGAGCA CCTCAGGTCC CGGACGCTCC AGAGACACCA CACGATCCAG 
AACAGCGACG ATGCCTATGT ACAGCTGGAT ACCTTGCCAG GAATGAGCCT GGTGGCAGGC 
AAGGCGCTGA GCTCTGCCCG GATGTCAGAT GCAGTTCTTA GTCAGTCTTC ACTCATGGGC 
AGCCAACAGT TTCAGGATGA GGAAGATGAA GAATGTGGGG TGAGCCTGGG CCACGAGCAT 
CCAGGCCTGG GTGATGGCAG CCAGCATCTC AACTCCTCTC GCTATCCAGC TACGTGTGTT 
ACAGACATCA TGCTCAGCCA CAAGCACCCA GAGGTCTCCT TCAGCATGGA GCAAGCCGGC 
GTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Salt-inducible kinase 3 regulates the mammalian circadian clock by destabilizing PER2 protein.
eLife6(2017 Dec)
Hayasaka N,Hirano A,Miyoshi Y,Tokuda IT,Yoshitane H,Matsuda J,Fukada Y

Inhibition of SIK2 and SIK3 during differentiation enhances the anti-inflammatory phenotype of macrophages.
The Biochemical journal474(4)521-537(2017 02)
Darling NJ,Toth R,Arthur JS,Clark K

Forward-genetics analysis of sleep in randomly mutagenized mice.
Nature539(7629)378-383(2016 11)
Funato H,Miyoshi C,Fujiyama T,Kanda T,Sato M,Wang Z,Ma J,Nakane S,Tomita J,Ikkyu A,Kakizaki M,Hotta-Hirashima N,Kanno S,Komiya H,Asano F,Honda T,Kim SJ,Harano K,Muramoto H,Yonezawa T,Mizuno S,Miyazaki S,Connor L,Kumar V,Miura I,Suzuki T,Watanabe A,Abe M,Sugiyama F,Takahashi S,Sakimura K,Hayashi Y,Liu Q,Kume K,Wakana S,Takahashi JS,Yanagisawa M

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Sik3 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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