Rab3b cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Rab3b
Entrez Gene ID	69908
Full Name	RAB3B, member RAS oncogene family
Synonyms	2610528C18Rik
General protein information	Preferred Names RAB3B, member RAS oncogene family Names ras-related protein Rab-3B
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 4 Map Location: 4\|4 C7

mRNA and Protein(s)

mRNA	Protein	Name
NM_023537.5	NP_076026.1	ras-related protein Rab-3B

Pathways from BioSystems

Homologies

Bos taurus (cattle)	RAB3B	NP_776872.1
Xenopus tropicalis (tropical clawed frog)	rab3b	NP_001093746.1
Mus musculus (house mouse)	Rab3b	NP_076026.1
Gallus gallus (chicken)	RAB3B	XP_422470.2
Homo sapiens (human)	RAB3B	NP_002858.2
Canis lupus familiaris (dog)	RAB3B	XP_849630.1
Danio rerio (zebrafish)	rab3b	XP_685654.3
Pan troglodytes (chimpanzee)	RAB3B	XP_001143400.1
	RAB3B	XP_001111269.1
Rattus norvegicus (Norway rat)	Rab3b	NP_112353.1

Gene Ontology
Bibliography

Related articles in PubMed

Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates.
Miller JA, Nathanson J, Franjic D, Shim S, Dalley RA, Shapouri S, Smith KA, Sunkin SM, Bernard A, Bennett JL, Lee CK, Hawrylycz MJ, Jones AR, Amaral DG, ?estan N, Gage FH, Lein ES
Development (Cambridge, England)140(22)4633-44(2013 Nov)

Rab3B protein is required for long-term depression of hippocampal inhibitory synapses and for normal reversal learning.
Tsetsenis T, Younts TJ, Chiu CQ, Kaeser PS, Castillo PE, S?dhof TC
Proceedings of the National Academy of Sciences of the United States of America108(34)14300-5(2011 Aug)

Tctex-1, a novel interaction partner of Rab3D, is required for osteoclastic bone resorption.
Pavlos NJ, Cheng TS, Qin A, Ng PY, Feng HT, Ang ES, Carrello A, Sung CH, Jahn R, Zheng MH, Xu J
Molecular and cellular biology31(7)1551-64(2011 Apr)

Rab3 proteins involved in vesicle biogenesis and priming in embryonic mouse chromaffin cells.
Schonn JS, van Weering JR, Mohrmann R, Schl?ter OM, S?dhof TC, de Wit H, Verhage M, S?rensen JB
Traffic (Copenhagen, Denmark)11(11)1415-28(2010 Nov)

The GTPase Rab3b/3c-positive recycling vesicles are involved in cross-presentation in dendritic cells.
Zou L, Zhou J, Zhang J, Li J, Liu N, Chai L, Li N, Liu T, Li L, Xie Z, Liu H, Wan Y, Wu Y
Proceedings of the National Academy of Sciences of the United States of America106(37)15801-6(2009 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Presynaptic forms of long-term plasticity at excitatory and inhibitory synapses generally are mediated by a common Rab3/RIM-dependent pathway, with various types of synapses using distinct Rab3 isoforms.
Title: Rab3B protein is required for long-term depression of hippocampal inhibitory synapses and for normal reversal learning.

Rab3b/3c-positive recycling vesicles are involved in and may constitute one of the recycling compartments in exogenous antigen cross-presentation.
Title: The GTPase Rab3b/3c-positive recycling vesicles are involved in cross-presentation in dendritic cells.

Gas8 was specifically interacted with the GTP-bound form of Rab3B and co-localized with Rab3B at the Golgi in NIH 3T3 cells
Title: Interaction of Rab3B with microtubule-binding protein Gas8 in NIH 3T3 cells.

Rab3-induced modifications to primed vesicles causes a transient increase in the transduction efficacy of synaptic action potential trains and optimizes the encoding of synaptic information at an intermediate spike frequency range.
Title: Rab3 superprimes synaptic vesicles for release: implications for short-term synaptic plasticity.

The following Rab3b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Rab3b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu03928	NM_023537.5 Latest version!	Mus musculus RAB3B, member RAS oncogene family (Rab3b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Rab3b ( NM_023537.5 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_076026.1 Mus musculus RAB3B, member RAS oncogene family (Rab3b), mRNA.

Price & Availability↑

CloneID	OMu03928
Clone ID Related Accession (Same CDS sequence)	NM_023537.5
Accession Version	NM_023537.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 660bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	ras-related protein Rab-3B
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AL607070.19. On Nov 17, 2006 this sequence version replaced NM_023537.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK082959.1, SRR1660817.232054.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849378, SAMN00849379 [ECO:0000348] ##Evidence-Data-END##

ATGGCTTCAG TGACTGATGG TAAGACTGGA ATCAAAGATG CCTCCGACCA GAACTTTGAC 
TACATGTTCA AACTGCTCAT CATTGGCAAC AGCAGCGTCG GGAAGACCTC CTTCCTTTTC 
CGCTATGCTG ATGACACCTT CACCCCTGCC TTTGTCAGCA CTGTGGGTAT CGACTTCAAA 
GTGAAGACAG TCTACCGCCA TGAGAAGCGT GTGAAGCTGC AGATATGGGA CACAGCTGGG 
CAAGAGCGGT ACCGGACCAT CACCACAGCC TACTACCGTG GGGCCATGGG CTTCATTCTC 
ATGTATGACA TCACCAACGA GGAGTCCTTC AATGCTGTCC AGGACTGGGC TACTCAGATT 
AAGACCTACT CCTGGGACAA CGCACAGGTC ATTCTCGTGG GAAATAAGTG TGACATGGAA 
GAGGAAAGAG TGGTCCCAAC TGAGAAGGGC CGGCTCCTGG CAGAACAGCT TGGGTTTGAC 
TTCTTTGAAG CCAGCGCCAA GGAGAACATC AGTGTGAGGC AGGCCTTCGA GCGGCTGGTG 
GATGCCATCT GCGATAAGAT GTCTGACTCG ATGGACACAG ACCCCTCCGT GCTAGGCGCC 
TCCAAGACGA CGCGGCTCTC AGACACCCCA CCTCTGCTGC AGCAGAACTG CTCTTGTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_076026.1
CDS	150..809
Translation	MASVTDGKTGIKDASDQNFDYMFKLLIIGNSSVGKTSFLFRYADDTFTPAFVSTVGIDFKVKTVYRHEKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWATQIKTYSWDNAQVILVGNKCDMEEERVVPTEKGRLLAEQLGFDFFEASAKENISVRQAFERLVDAICDKMSDSMDTDPSVLGASKTTRLSDTPPLLQQNCSC

Target ORF information:

RefSeq Version	NM_023537.5
Organism	Mus musculus(house mouse)
Definition	Mus musculus RAB3B, member RAS oncogene family (Rab3b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_023537.5

ORF Insert Sequence:

ATGGCTTCAG TGACTGATGG TAAGACTGGA ATCAAAGATG CCTCCGACCA GAACTTTGAC 
TACATGTTCA AACTGCTCAT CATTGGCAAC AGCAGCGTCG GGAAGACCTC CTTCCTTTTC 
CGCTATGCTG ATGACACCTT CACCCCTGCC TTTGTCAGCA CTGTGGGTAT CGACTTCAAA 
GTGAAGACAG TCTACCGCCA TGAGAAGCGT GTGAAGCTGC AGATATGGGA CACAGCTGGG 
CAAGAGCGGT ACCGGACCAT CACCACAGCC TACTACCGTG GGGCCATGGG CTTCATTCTC 
ATGTATGACA TCACCAACGA GGAGTCCTTC AATGCTGTCC AGGACTGGGC TACTCAGATT 
AAGACCTACT CCTGGGACAA CGCACAGGTC ATTCTCGTGG GAAATAAGTG TGACATGGAA 
GAGGAAAGAG TGGTCCCAAC TGAGAAGGGC CGGCTCCTGG CAGAACAGCT TGGGTTTGAC 
TTCTTTGAAG CCAGCGCCAA GGAGAACATC AGTGTGAGGC AGGCCTTCGA GCGGCTGGTG 
GATGCCATCT GCGATAAGAT GTCTGACTCG ATGGACACAG ACCCCTCCGT GCTAGGCGCC 
TCCAAGACGA CGCGGCTCTC AGACACCCCA CCTCTGCTGC AGCAGAACTG CTCTTGTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates.
Development (Cambridge, England)140(22)4633-44(2013 Nov)
Miller JA,Nathanson J,Franjic D,Shim S,Dalley RA,Shapouri S,Smith KA,Sunkin SM,Bernard A,Bennett JL,Lee CK,Hawrylycz MJ,Jones AR,Amaral DG,?estan N,Gage FH,Lein ES

Rab3B protein is required for long-term depression of hippocampal inhibitory synapses and for normal reversal learning.
Proceedings of the National Academy of Sciences of the United States of America108(34)14300-5(2011 Aug)
Tsetsenis T,Younts TJ,Chiu CQ,Kaeser PS,Castillo PE,S?dhof TC

Tctex-1, a novel interaction partner of Rab3D, is required for osteoclastic bone resorption.
Molecular and cellular biology31(7)1551-64(2011 Apr)
Pavlos NJ,Cheng TS,Qin A,Ng PY,Feng HT,Ang ES,Carrello A,Sung CH,Jahn R,Zheng MH,Xu J

Rab3 proteins involved in vesicle biogenesis and priming in embryonic mouse chromaffin cells.
Traffic (Copenhagen, Denmark)11(11)1415-28(2010 Nov)
Schonn JS,van Weering JR,Mohrmann R,Schl?ter OM,S?dhof TC,de Wit H,Verhage M,S?rensen JB

The GTPase Rab3b/3c-positive recycling vesicles are involved in cross-presentation in dendritic cells.
Proceedings of the National Academy of Sciences of the United States of America106(37)15801-6(2009 Sep)
Zou L,Zhou J,Zhang J,Li J,Liu N,Chai L,Li N,Liu T,Li L,Xie Z,Liu H,Wan Y,Wu Y

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Rab3b cDNA ORF clone, Mus musculus(house mouse)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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