Agpat2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Agpat2
Entrez Gene ID	67512
Full Name	1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)
Synonyms	2510002J07Rik,AV000834,BSCL,BSCL1,LPAAB,LPAAT-beta
General protein information	Preferred Names 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta) Names 1-acyl-sn-glycerol-3-phosphate acyltransferase beta 1-AGP acyltransferase 2 1-AGPAT 2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 2 Map Location: 2\|2 A3

mRNA and Protein(s)

mRNA	Protein	Name
XM_017319222.1	XP_017174711.1	1-acyl-sn-glycerol-3-phosphate acyltransferase beta isoform X1
NM_026212.2	NP_080488.1	1-acyl-sn-glycerol-3-phosphate acyltransferase beta precursor
XM_017319222.2	XP_017174711.1	1-acyl-sn-glycerol-3-phosphate acyltransferase beta isoform X1

Pathways from BioSystems

Homologies

	AGPAT2	XP_001094500.1
Bos taurus (cattle)	AGPAT2	NP_001073733.1
Rattus norvegicus (Norway rat)	Agpat2	NP_001101291.1
Homo sapiens (human)	AGPAT2	NP_006403.2
Gallus gallus (chicken)	AGPAT2	XP_001235300.2
Xenopus tropicalis (tropical clawed frog)	agpat2	NP_001123741.1
Pan troglodytes (chimpanzee)	AGPAT2	XP_001162511.3
Mus musculus (house mouse)	Agpat2	NP_080488.1
Canis lupus familiaris (dog)	AGPAT2	XP_548370.4

Gene Ontology
Bibliography

Related articles in PubMed

An adipo-biliary-uridine axis that regulates energy homeostasis.
Deng Y, Wang ZV, Gordillo R, An Y, Zhang C, Liang Q, Yoshino J, Cautivo KM, De Brabander J, Elmquist JK, Horton JD, Hill JA, Klein S, Scherer PE
Science (New York, N.Y.)355(6330)(2017 03)

AGPAT2 is essential for postnatal development and maintenance of white and brown adipose tissue.
Cautivo KM, Lizama CO, Tapia PJ, Agarwal AK, Garg A, Horton JD, Cort?s VA
Molecular metabolism5(7)491-505(2016 Jul)

Mogat1 deletion does not ameliorate hepatic steatosis in lipodystrophic (Agpat2-/-) or obese (ob/ob) mice.
Agarwal AK, Tunison K, Dalal JS, Yen CL, Farese RV Jr, Horton JD, Garg A
Journal of lipid research57(4)616-30(2016 Apr)

Perinatal deiodinase 2 expression in hepatocytes defines epigenetic susceptibility to liver steatosis and obesity.
Fonseca TL, Fernandes GW, McAninch EA, Bocco BM, Abdalla SM, Ribeiro MO, Moh?csik P, Fekete C, Li D, Xing X, Wang T, Gereben B, Bianco AC
Proceedings of the National Academy of Sciences of the United States of America112(45)14018-23(2015 Nov)

AGPAT2 deficiency impairs adipogenic differentiation in primary cultured preadipocytes in a non-autophagy or apoptosis dependent mechanism.
Fern?ndez-Galilea M, Tapia P, Cautivo K, Morselli E, Cort?s VA
Biochemical and biophysical research communications467(1)39-45(2015 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Adipogenically induced Agpat2(-/-) preadipocytes had fewer lipid-loaded cells and lower levels of adipocyte markers than wild type preadipocytes.
Title: AGPAT2 deficiency impairs adipogenic differentiation in primary cultured preadipocytes in a non-autophagy or apoptosis dependent mechanism.

The lack of normal insulin signaling in Agpat2(-/-) livers allows unrestricted phosphatidic acid-induced gluconeogenesis.
Title: Hepatic gluconeogenesis is enhanced by phosphatidic acid which remains uninhibited by insulin in lipodystrophic Agpat2-/- mice.

Leptin ameliorates insulin resistance and hepatic steatosis in Agpat2-/- lipodystrophic mice independent of hepatocyte leptin receptors
Title: Leptin ameliorates insulin resistance and hepatic steatosis in Agpat2-/- lipodystrophic mice independent of hepatocyte leptin receptors.

Data suggest that Agpat2 regulates adipogenesis through modulation of lipid metabolism/signal transduction, altering normal activation of phosphatidylinositol 3-kinase (PI3K)/protooncogene c-Akt and PPARgamma signaling in early stage of adipogenesis.
Title: Alterations in lipid signaling underlie lipodystrophy secondary to AGPAT2 mutations.

the role of AGPAT1 or AGPAT2 in liver lipogenesis is minimal and that accumulation of liver fat is primarily a consequence of insulin resistance
Title: Human 1-acylglycerol-3-phosphate O-acyltransferase isoforms 1 and 2: biochemical characterization and inability to rescue hepatic steatosis in Agpat2(-/-) gene lipodystrophic mice.

The following Agpat2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Agpat2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu19643	NM_026212.2 Latest version!	Mus musculus 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta) (Agpat2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
OMu80395	XM_017319222.2 Latest version!	Mus musculus 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta) (Agpat2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OMu80395	XM_017319222.1	Mus musculus 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta) (Agpat2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Agpat2 ( XM_017319222.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_017174711.1 Mus musculus 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta) (Agpat2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu80395
Clone ID Related Accession (Same CDS sequence)	XM_017319222.1 , XM_017319222.2
Accession Version	XM_017319222.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 528bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	1-acyl-sn-glycerol-3-phosphate acyltransferase beta isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000068.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATGGGTC TCATGGAAAT ACTCCCTAAG CGCTGTGTGC AGATCGCCAA GCGTGAGCTA 
ATGTTCACAG GGCCTGTGGG CCTCATCATG TACCTTGGGG GTGTCTACTT CATCAACCGC 
CAGCAAGCCA GAACTGCCAT GTCTGTGATG GCCGACCTGG GCGACCTCAT GGTCAAGGAG 
AATCTCAAAG TGTGGATCTA CCCAGAGGGT ACACGCAACG ACAATGGGGA CCTGTTGCCC 
TTTAAAAAAG GAGCCTTCTA CTTGGCCATC CAGGCCCAGG TGCCCATCAT CCCCGTGGTG 
TACTCGTCTT TCTCTTCCTT CTACAATGTC AAGACGAAGC TCTTCACCTC AGGAACAATC 
AAGGTACAAG TGCTGGATGC TGTCCCTACC AATGGTCTGA CAGATGCTGA TGTCACCAAG 
CTGGTGGACA CTTGCTACCA GTCCATGAGG GCCACCTTTC TACAGATTTC TCAGATTCCC 
CAAGAGAACT CTGCCATTAA GGAGCCTGGG GTCTTGCCAG CCCAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017174711.1
CDS	218..745
Translation	MMGLMEILPKRCVQIAKRELMFTGPVGLIMYLGGVYFINRQQARTAMSVMADLGDLMVKENLKVWIYPEGTRNDNGDLLPFKKGAFYLAIQAQVPIIPVVYSSFSSFYNVKTKLFTSGTIKVQVLDAVPTNGLTDADVTKLVDTCYQSMRATFLQISQIPQENSAIKEPGVLPAQ

Target ORF information:

RefSeq Version	XM_017319222.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta) (Agpat2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017319222.1

ORF Insert Sequence:

ATGATGGGTC TCATGGAAAT ACTCCCTAAG CGCTGTGTGC AGATCGCCAA GCGTGAGCTA 
ATGTTCACAG GGCCTGTGGG CCTCATCATG TACCTTGGGG GTGTCTACTT CATCAACCGC 
CAGCAAGCCA GAACTGCCAT GTCTGTGATG GCCGACCTGG GCGACCTCAT GGTCAAGGAG 
AATCTCAAAG TGTGGATCTA CCCAGAGGGT ACACGCAACG ACAATGGGGA CCTGTTGCCC 
TTTAAAAAAG GAGCCTTCTA CTTGGCCATC CAGGCCCAGG TGCCCATCAT CCCCGTGGTG 
TACTCGTCTT TCTCTTCCTT CTACAATGTC AAGACGAAGC TCTTCACCTC AGGAACAATC 
AAGGTACAAG TGCTGGATGC TGTCCCTACC AATGGTCTGA CAGATGCTGA TGTCACCAAG 
CTGGTGGACA CTTGCTACCA GTCCATGAGG GCCACCTTTC TACAGATTTC TCAGATTCCC 
CAAGAGAACT CTGCCATTAA GGAGCCTGGG GTCTTGCCAG CCCAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Agpat2 ( NM_026212.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_080488.1 Mus musculus 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta) (Agpat2), mRNA.

Price & Availability↑

CloneID	OMu19643
Clone ID Related Accession (Same CDS sequence)	NM_026212.2
Accession Version	NM_026212.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 837bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-05
Organism	Mus musculus(house mouse)
Product	1-acyl-sn-glycerol-3-phosphate acyltransferase beta precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BB871777.1, BC125530.1, AK002422.1 and AL732311.13. On Feb 13, 2013 this sequence version replaced NM_026212.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK010891.1, BC125530.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849379 [ECO:0000348] ##Evidence-Data-END##

ATGGACCCGT GGCCATGGCT GACGGCGGCG CTGCTGCTGC TGTTGCTGCT TGTGCAGCTG 
AGCCGCACAG CCAGGTTCTA CGCCAAGGTC GGTCTCTACT GCGTGCTCTG CCTGTCCTTC 
TCCGCCGCGG CCTCGATCGT CTGCCTGCTG CGCCACGGCG GCCGCACCGT GGATAACATG 
AGCATCATCA GCTGGTTCGT TCGGTCCTTC AAGTACGTGT ATGGCCTTCG CTTTGAGGTC 
AGCGGACAGA AGAAACTGGA GGTGGATGGT CCCTGTGTCA TCATCTCTAA TCACCAGAGC 
ATCCTGGACA TGATGGGTCT CATGGAAATA CTCCCTAAGC GCTGTGTGCA GATCGCCAAG 
CGTGAGCTAA TGTTCACAGG GCCTGTGGGC CTCATCATGT ACCTTGGGGG TGTCTACTTC 
ATCAACCGCC AGCAAGCCAG AACTGCCATG TCTGTGATGG CCGACCTGGG CGACCTCATG 
GTCAAGGAGA ATCTCAAAGT GTGGATCTAC CCAGAGGGTA CACGCAACGA CAATGGGGAC 
CTGTTGCCCT TTAAAAAAGG AGCCTTCTAC TTGGCCATCC AGGCCCAGGT GCCCATCATC 
CCCGTGGTGT ACTCGTCTTT CTCTTCCTTC TACAATGTCA AGACGAAGCT CTTCACCTCA 
GGAACAATCA AGGTACAAGT GCTGGATGCT GTCCCTACCA ATGGTCTGAC AGATGCTGAT 
GTCACCAAGC TGGTGGACAC TTGCTACCAG TCCATGAGGG CCACCTTTCT ACAGATTTCT 
CAGATTCCCC AAGAGAACTC TGCCATTAAG GAGCCTGGGG TCTTGCCAGC CCAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_080488.1
CDS	208..1044
Translation	MDPWPWLTAALLLLLLLVQLSRTARFYAKVGLYCVLCLSFSAAASIVCLLRHGGRTVDNMSIISWFVRSFKYVYGLRFEVSGQKKLEVDGPCVIISNHQSILDMMGLMEILPKRCVQIAKRELMFTGPVGLIMYLGGVYFINRQQARTAMSVMADLGDLMVKENLKVWIYPEGTRNDNGDLLPFKKGAFYLAIQAQVPIIPVVYSSFSSFYNVKTKLFTSGTIKVQVLDAVPTNGLTDADVTKLVDTCYQSMRATFLQISQIPQENSAIKEPGVLPAQ

Target ORF information:

RefSeq Version	NM_026212.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta) (Agpat2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_026212.2

ORF Insert Sequence:

ATGGACCCGT GGCCATGGCT GACGGCGGCG CTGCTGCTGC TGTTGCTGCT TGTGCAGCTG 
AGCCGCACAG CCAGGTTCTA CGCCAAGGTC GGTCTCTACT GCGTGCTCTG CCTGTCCTTC 
TCCGCCGCGG CCTCGATCGT CTGCCTGCTG CGCCACGGCG GCCGCACCGT GGATAACATG 
AGCATCATCA GCTGGTTCGT TCGGTCCTTC AAGTACGTGT ATGGCCTTCG CTTTGAGGTC 
AGCGGACAGA AGAAACTGGA GGTGGATGGT CCCTGTGTCA TCATCTCTAA TCACCAGAGC 
ATCCTGGACA TGATGGGTCT CATGGAAATA CTCCCTAAGC GCTGTGTGCA GATCGCCAAG 
CGTGAGCTAA TGTTCACAGG GCCTGTGGGC CTCATCATGT ACCTTGGGGG TGTCTACTTC 
ATCAACCGCC AGCAAGCCAG AACTGCCATG TCTGTGATGG CCGACCTGGG CGACCTCATG 
GTCAAGGAGA ATCTCAAAGT GTGGATCTAC CCAGAGGGTA CACGCAACGA CAATGGGGAC 
CTGTTGCCCT TTAAAAAAGG AGCCTTCTAC TTGGCCATCC AGGCCCAGGT GCCCATCATC 
CCCGTGGTGT ACTCGTCTTT CTCTTCCTTC TACAATGTCA AGACGAAGCT CTTCACCTCA 
GGAACAATCA AGGTACAAGT GCTGGATGCT GTCCCTACCA ATGGTCTGAC AGATGCTGAT 
GTCACCAAGC TGGTGGACAC TTGCTACCAG TCCATGAGGG CCACCTTTCT ACAGATTTCT 
CAGATTCCCC AAGAGAACTC TGCCATTAAG GAGCCTGGGG TCTTGCCAGC CCAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Agpat2 ( XM_017319222.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_017174711.1 Mus musculus 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta) (Agpat2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu80395
Clone ID Related Accession (Same CDS sequence)	XM_017319222.1 , XM_017319222.2
Accession Version	XM_017319222.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 528bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	1-acyl-sn-glycerol-3-phosphate acyltransferase beta isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000068.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_017319222.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATGGGTC TCATGGAAAT ACTCCCTAAG CGCTGTGTGC AGATCGCCAA GCGTGAGCTA 
ATGTTCACAG GGCCTGTGGG CCTCATCATG TACCTTGGGG GTGTCTACTT CATCAACCGC 
CAGCAAGCCA GAACTGCCAT GTCTGTGATG GCCGACCTGG GCGACCTCAT GGTCAAGGAG 
AATCTCAAAG TGTGGATCTA CCCAGAGGGT ACACGCAACG ACAATGGGGA CCTGTTGCCC 
TTTAAAAAAG GAGCCTTCTA CTTGGCCATC CAGGCCCAGG TGCCCATCAT CCCCGTGGTG 
TACTCGTCTT TCTCTTCCTT CTACAATGTC AAGACGAAGC TCTTCACCTC AGGAACAATC 
AAGGTACAAG TGCTGGATGC TGTCCCTACC AATGGTCTGA CAGATGCTGA TGTCACCAAG 
CTGGTGGACA CTTGCTACCA GTCCATGAGG GCCACCTTTC TACAGATTTC TCAGATTCCC 
CAAGAGAACT CTGCCATTAA GGAGCCTGGG GTCTTGCCAG CCCAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017174711.1
CDS	292..819
Translation	MMGLMEILPKRCVQIAKRELMFTGPVGLIMYLGGVYFINRQQARTAMSVMADLGDLMVKENLKVWIYPEGTRNDNGDLLPFKKGAFYLAIQAQVPIIPVVYSSFSSFYNVKTKLFTSGTIKVQVLDAVPTNGLTDADVTKLVDTCYQSMRATFLQISQIPQENSAIKEPGVLPAQ

Target ORF information:

RefSeq Version	XM_017319222.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta) (Agpat2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017319222.2

ORF Insert Sequence:

ATGATGGGTC TCATGGAAAT ACTCCCTAAG CGCTGTGTGC AGATCGCCAA GCGTGAGCTA 
ATGTTCACAG GGCCTGTGGG CCTCATCATG TACCTTGGGG GTGTCTACTT CATCAACCGC 
CAGCAAGCCA GAACTGCCAT GTCTGTGATG GCCGACCTGG GCGACCTCAT GGTCAAGGAG 
AATCTCAAAG TGTGGATCTA CCCAGAGGGT ACACGCAACG ACAATGGGGA CCTGTTGCCC 
TTTAAAAAAG GAGCCTTCTA CTTGGCCATC CAGGCCCAGG TGCCCATCAT CCCCGTGGTG 
TACTCGTCTT TCTCTTCCTT CTACAATGTC AAGACGAAGC TCTTCACCTC AGGAACAATC 
AAGGTACAAG TGCTGGATGC TGTCCCTACC AATGGTCTGA CAGATGCTGA TGTCACCAAG 
CTGGTGGACA CTTGCTACCA GTCCATGAGG GCCACCTTTC TACAGATTTC TCAGATTCCC 
CAAGAGAACT CTGCCATTAA GGAGCCTGGG GTCTTGCCAG CCCAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

An adipo-biliary-uridine axis that regulates energy homeostasis.
Science (New York, N.Y.)355(6330)(2017 03)
Deng Y,Wang ZV,Gordillo R,An Y,Zhang C,Liang Q,Yoshino J,Cautivo KM,De Brabander J,Elmquist JK,Horton JD,Hill JA,Klein S,Scherer PE

AGPAT2 is essential for postnatal development and maintenance of white and brown adipose tissue.
Molecular metabolism5(7)491-505(2016 Jul)
Cautivo KM,Lizama CO,Tapia PJ,Agarwal AK,Garg A,Horton JD,Cort?s VA

Mogat1 deletion does not ameliorate hepatic steatosis in lipodystrophic (Agpat2-/-) or obese (ob/ob) mice.
Journal of lipid research57(4)616-30(2016 Apr)
Agarwal AK,Tunison K,Dalal JS,Yen CL,Farese RV Jr,Horton JD,Garg A

Perinatal deiodinase 2 expression in hepatocytes defines epigenetic susceptibility to liver steatosis and obesity.
Proceedings of the National Academy of Sciences of the United States of America112(45)14018-23(2015 Nov)
Fonseca TL,Fernandes GW,McAninch EA,Bocco BM,Abdalla SM,Ribeiro MO,Moh?csik P,Fekete C,Li D,Xing X,Wang T,Gereben B,Bianco AC

AGPAT2 deficiency impairs adipogenic differentiation in primary cultured preadipocytes in a non-autophagy or apoptosis dependent mechanism.
Biochemical and biophysical research communications467(1)39-45(2015 Nov)
Fern?ndez-Galilea M,Tapia P,Cautivo K,Morselli E,Cort?s VA

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Agpat2 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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