Ms4a4b cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ms4a4b
Entrez Gene ID	60361
Full Name	membrane-spanning 4-domains, subfamily A, member 4B
Synonyms	AI463180,Chandra,Ly116
General protein information	Preferred Names membrane-spanning 4-domains, subfamily A, member 4B Names membrane-spanning 4-domains, subfamily A, member 4B lymphocyte antigen 116
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 19 Map Location: 19\|19 A

mRNA and Protein(s)

mRNA	Protein	Name
NM_021718.2	NP_068364.1	membrane-spanning 4-domains, subfamily A, member 4B
XM_030251018.1	XP_030106878.1	membrane-spanning 4-domains, subfamily A, member 4B isoform X1
XM_030251019.1	XP_030106879.1	membrane-spanning 4-domains, subfamily A, member 4B isoform X1

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Ms4a4b	NP_068364.1
Mus musculus (house mouse)	Ms4a4c	NP_083775.1
Mus musculus (house mouse)	Ms4a4d	NP_079934.2

Gene Ontology
Bibliography

Related articles in PubMed

Anti-MS4a4B treatment abrogates MS4a4B-mediated protection in T cells and ameliorates experimental autoimmune encephalomyelitis.
Yan Y, Li Z, Zhang GX, Williams MS, Carey GB, Zhang J, Rostami A, Xu H
Apoptosis : an international journal on programmed cell death18(9)1106-19(2013 Sep)

TCR stimulation upregulates MS4a4B expression through induction of AP-1 transcription factor during T cell activation.
Yan Y, Zhang GX, Williams MS, Carey GB, Li H, Yang J, Rostami A, Xu H
Molecular immunology52(2)71-8(2012 Sep)

MS4a4B, a CD20 homologue in T cells, inhibits T cell propagation by modulation of cell cycle.
Xu H, Yan Y, Williams MS, Carey GB, Yang J, Li H, Zhang GX, Rostami A
PloS one5(11)e13780(2010 Nov)

A mouse knockout library for secreted and transmembrane proteins.
Tang T, Li L, Tang J, Li Y, Lin WY, Martin F, Grant D, Solloway M, Parker L, Ye W, Forrest W, Ghilardi N, Oravecz T, Platt KA, Rice DS, Hansen GM, Abuin A, Eberhart DE, Godowski P, Holt KH, Peterson A, Zambrowicz BP, de Sauvage FJ
Nature biotechnology28(7)749-55(2010 Jul)

MS4A4B is a GITR-associated membrane adapter, expressed by regulatory T cells, which modulates T cell activation.
Howie D, Nolan KF, Daley S, Butterfield E, Adams E, Garcia-Rueda H, Thompson C, Saunders NJ, Cobbold SP, Tone Y, Tone M, Waldmann H
Journal of immunology (Baltimore, Md. : 1950)183(7)4197-204(2009 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

MS4a4B regulated both T cell proliferation and T cell apoptosis.
Title: Anti-MS4a4B treatment abrogates MS4a4B-mediated protection in T cells and ameliorates experimental autoimmune encephalomyelitis.

TCR-stimulation induces transactivation of AP-1 transcription factor, which subsequently binds to the MS4a4B promoter and upregulates expression of MS4a4B in activated T cells.
Title: TCR stimulation upregulates MS4a4B expression through induction of AP-1 transcription factor during T cell activation.

Data indicate that MS4a4B negatively regulates T cell proliferation, and MS4a4B may serve as a modulator in the negative-feedback regulatory loop of activated T cells.
Title: MS4a4B, a CD20 homologue in T cells, inhibits T cell propagation by modulation of cell cycle.

study identified a molecular imprint of CD27-proficient CD4+ T cell help in CD8+ memory T cells in the form of the MS4A4B molecule
Title: CD27 instructs CD4+ T cells to provide help for the memory CD8+ T cell response after protein immunization.

MS4a4B expression is tightly regulated during T-cell development and MS4a4B expression promotes Th1 function and/or differentiation.
Title: Patterns of expression, membrane localization, and effects of ectopic expression suggest a function for MS4a4B, a CD20 homolog in Th1 T cells.

The following Ms4a4b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ms4a4b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu20696	NM_021718.2 Latest version!	Mus musculus membrane-spanning 4-domains, subfamily A, member 4B (Ms4a4b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu20696	XM_030251019.1 Latest version!	Mus musculus membrane-spanning 4-domains, subfamily A, member 4B (Ms4a4b), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OMu20696	XM_030251018.1 Latest version!	Mus musculus membrane-spanning 4-domains, subfamily A, member 4B (Ms4a4b), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ms4a4b ( NM_021718.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_068364.1 Mus musculus membrane-spanning 4-domains, subfamily A, member 4B (Ms4a4b), mRNA.

Price & Availability↑

CloneID	OMu20696
Clone ID Related Accession (Same CDS sequence)	NM_021718.2 , XM_030251018.1 , XM_030251019.1
Accession Version	NM_021718.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 681bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-25
Organism	Mus musculus(house mouse)
Product	membrane-spanning 4-domains, subfamily A, member 4B
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK080934.1, AK138737.1 and AF230640.1. On Sep 19, 2006 this sequence version replaced NM_021718.1. ##Evidence-Data-START## Transcript exon combination :: AF230640.1, AK138737.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGCAAGGAC AGGAACAGAC CACCATGGCA GTGGTTCCTG GAGTTGCTGT GCCTTCAAAG 
AATTCTGTTA TGACATCACA AATGTGGAAT GAGAAGAAAG AGAAATTCTT GAAGGGGGAA 
CCCAAAGTCC TTGGGGTTTT ACAAGTGATG ATTGCTATCA TAAACCTCAG CTTAGGAATA 
ATAATTTTGA CAACTTTATT TTCTGAACTA CCCACTTCAG TGATGTTAAT GGTCCCAATT 
TGGGGATCAA TAATGTTCAT TGTCTCCGGA TCCCTGTCCA TTGCAGCAGG AGTGACACCT 
ACAAAATGCC TGATCGTTGC CAGTCTAACT CTGAACACTA TCACCTCTGT GTTGGCTGCA 
ACTGCAAGCA TAATGGGTGT AGTCAGTGTG GCTGTGGGTT CACAGTTTCC GTTTCGGTAT 
AATTATACAA TCACCAAGGG TTTGGATGTT TTGATGTTAA TTTTCAATAT GCTAGAATTC 
TGCCTTGCTG TGTCCGTCTC TGCATTTGGA TGTGAAGCTT CCTGTTGTAA CTCCCGTGAG 
GTTCTTGTAG TGCTACCATC AAATCCTGTT GAGACAGTGA TGGCACCCCC AATGACACTT 
CAACCATTGC TACCATCAGA ACACCAAGGG ACCAATGTTC CAGGAAATGT GTACAAGAAC 
CACCCAGGAG AAATAGTCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_068364.1
CDS	129..809
Translation	MQGQEQTTMAVVPGVAVPSKNSVMTSQMWNEKKEKFLKGEPKVLGVLQVMIAIINLSLGIIILTTLFSELPTSVMLMVPIWGSIMFIVSGSLSIAAGVTPTKCLIVASLTLNTITSVLAATASIMGVVSVAVGSQFPFRYNYTITKGLDVLMLIFNMLEFCLAVSVSAFGCEASCCNSREVLVVLPSNPVETVMAPPMTLQPLLPSEHQGTNVPGNVYKNHPGEIV

Target ORF information:

RefSeq Version	NM_021718.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus membrane-spanning 4-domains, subfamily A, member 4B (Ms4a4b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021718.2

ORF Insert Sequence:

ATGCAAGGAC AGGAACAGAC CACCATGGCA GTGGTTCCTG GAGTTGCTGT GCCTTCAAAG 
AATTCTGTTA TGACATCACA AATGTGGAAT GAGAAGAAAG AGAAATTCTT GAAGGGGGAA 
CCCAAAGTCC TTGGGGTTTT ACAAGTGATG ATTGCTATCA TAAACCTCAG CTTAGGAATA 
ATAATTTTGA CAACTTTATT TTCTGAACTA CCCACTTCAG TGATGTTAAT GGTCCCAATT 
TGGGGATCAA TAATGTTCAT TGTCTCCGGA TCCCTGTCCA TTGCAGCAGG AGTGACACCT 
ACAAAATGCC TGATCGTTGC CAGTCTAACT CTGAACACTA TCACCTCTGT GTTGGCTGCA 
ACTGCAAGCA TAATGGGTGT AGTCAGTGTG GCTGTGGGTT CACAGTTTCC GTTTCGGTAT 
AATTATACAA TCACCAAGGG TTTGGATGTT TTGATGTTAA TTTTCAATAT GCTAGAATTC 
TGCCTTGCTG TGTCCGTCTC TGCATTTGGA TGTGAAGCTT CCTGTTGTAA CTCCCGTGAG 
GTTCTTGTAG TGCTACCATC AAATCCTGTT GAGACAGTGA TGGCACCCCC AATGACACTT 
CAACCATTGC TACCATCAGA ACACCAAGGG ACCAATGTTC CAGGAAATGT GTACAAGAAC 
CACCCAGGAG AAATAGTCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ms4a4b ( XM_030251018.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030106878.1 Mus musculus membrane-spanning 4-domains, subfamily A, member 4B (Ms4a4b), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu20696
Clone ID Related Accession (Same CDS sequence)	NM_021718.2 , XM_030251018.1 , XM_030251019.1
Accession Version	XM_030251018.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 681bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	membrane-spanning 4-domains, subfamily A, member 4B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000085.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAAGGAC AGGAACAGAC CACCATGGCA GTGGTTCCTG GAGTTGCTGT GCCTTCAAAG 
AATTCTGTTA TGACATCACA AATGTGGAAT GAGAAGAAAG AGAAATTCTT GAAGGGGGAA 
CCCAAAGTCC TTGGGGTTTT ACAAGTGATG ATTGCTATCA TAAACCTCAG CTTAGGAATA 
ATAATTTTGA CAACTTTATT TTCTGAACTA CCCACTTCAG TGATGTTAAT GGTCCCAATT 
TGGGGATCAA TAATGTTCAT TGTCTCCGGA TCCCTGTCCA TTGCAGCAGG AGTGACACCT 
ACAAAATGCC TGATCGTTGC CAGTCTAACT CTGAACACTA TCACCTCTGT GTTGGCTGCA 
ACTGCAAGCA TAATGGGTGT AGTCAGTGTG GCTGTGGGTT CACAGTTTCC GTTTCGGTAT 
AATTATACAA TCACCAAGGG TTTGGATGTT TTGATGTTAA TTTTCAATAT GCTAGAATTC 
TGCCTTGCTG TGTCCGTCTC TGCATTTGGA TGTGAAGCTT CCTGTTGTAA CTCCCGTGAG 
GTTCTTGTAG TGCTACCATC AAATCCTGTT GAGACAGTGA TGGCACCCCC AATGACACTT 
CAACCATTGC TACCATCAGA ACACCAAGGG ACCAATGTTC CAGGAAATGT GTACAAGAAC 
CACCCAGGAG AAATAGTCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030106878.1
CDS	130..810
Translation	MQGQEQTTMAVVPGVAVPSKNSVMTSQMWNEKKEKFLKGEPKVLGVLQVMIAIINLSLGIIILTTLFSELPTSVMLMVPIWGSIMFIVSGSLSIAAGVTPTKCLIVASLTLNTITSVLAATASIMGVVSVAVGSQFPFRYNYTITKGLDVLMLIFNMLEFCLAVSVSAFGCEASCCNSREVLVVLPSNPVETVMAPPMTLQPLLPSEHQGTNVPGNVYKNHPGEIV

Target ORF information:

RefSeq Version	XM_030251018.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus membrane-spanning 4-domains, subfamily A, member 4B (Ms4a4b), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030251018.1

ORF Insert Sequence:

ATGCAAGGAC AGGAACAGAC CACCATGGCA GTGGTTCCTG GAGTTGCTGT GCCTTCAAAG 
AATTCTGTTA TGACATCACA AATGTGGAAT GAGAAGAAAG AGAAATTCTT GAAGGGGGAA 
CCCAAAGTCC TTGGGGTTTT ACAAGTGATG ATTGCTATCA TAAACCTCAG CTTAGGAATA 
ATAATTTTGA CAACTTTATT TTCTGAACTA CCCACTTCAG TGATGTTAAT GGTCCCAATT 
TGGGGATCAA TAATGTTCAT TGTCTCCGGA TCCCTGTCCA TTGCAGCAGG AGTGACACCT 
ACAAAATGCC TGATCGTTGC CAGTCTAACT CTGAACACTA TCACCTCTGT GTTGGCTGCA 
ACTGCAAGCA TAATGGGTGT AGTCAGTGTG GCTGTGGGTT CACAGTTTCC GTTTCGGTAT 
AATTATACAA TCACCAAGGG TTTGGATGTT TTGATGTTAA TTTTCAATAT GCTAGAATTC 
TGCCTTGCTG TGTCCGTCTC TGCATTTGGA TGTGAAGCTT CCTGTTGTAA CTCCCGTGAG 
GTTCTTGTAG TGCTACCATC AAATCCTGTT GAGACAGTGA TGGCACCCCC AATGACACTT 
CAACCATTGC TACCATCAGA ACACCAAGGG ACCAATGTTC CAGGAAATGT GTACAAGAAC 
CACCCAGGAG AAATAGTCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ms4a4b ( XM_030251019.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030106879.1 Mus musculus membrane-spanning 4-domains, subfamily A, member 4B (Ms4a4b), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu20696
Clone ID Related Accession (Same CDS sequence)	NM_021718.2 , XM_030251018.1 , XM_030251019.1
Accession Version	XM_030251019.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 681bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	membrane-spanning 4-domains, subfamily A, member 4B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000085.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAAGGAC AGGAACAGAC CACCATGGCA GTGGTTCCTG GAGTTGCTGT GCCTTCAAAG 
AATTCTGTTA TGACATCACA AATGTGGAAT GAGAAGAAAG AGAAATTCTT GAAGGGGGAA 
CCCAAAGTCC TTGGGGTTTT ACAAGTGATG ATTGCTATCA TAAACCTCAG CTTAGGAATA 
ATAATTTTGA CAACTTTATT TTCTGAACTA CCCACTTCAG TGATGTTAAT GGTCCCAATT 
TGGGGATCAA TAATGTTCAT TGTCTCCGGA TCCCTGTCCA TTGCAGCAGG AGTGACACCT 
ACAAAATGCC TGATCGTTGC CAGTCTAACT CTGAACACTA TCACCTCTGT GTTGGCTGCA 
ACTGCAAGCA TAATGGGTGT AGTCAGTGTG GCTGTGGGTT CACAGTTTCC GTTTCGGTAT 
AATTATACAA TCACCAAGGG TTTGGATGTT TTGATGTTAA TTTTCAATAT GCTAGAATTC 
TGCCTTGCTG TGTCCGTCTC TGCATTTGGA TGTGAAGCTT CCTGTTGTAA CTCCCGTGAG 
GTTCTTGTAG TGCTACCATC AAATCCTGTT GAGACAGTGA TGGCACCCCC AATGACACTT 
CAACCATTGC TACCATCAGA ACACCAAGGG ACCAATGTTC CAGGAAATGT GTACAAGAAC 
CACCCAGGAG AAATAGTCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030106879.1
CDS	393..1073
Translation	MQGQEQTTMAVVPGVAVPSKNSVMTSQMWNEKKEKFLKGEPKVLGVLQVMIAIINLSLGIIILTTLFSELPTSVMLMVPIWGSIMFIVSGSLSIAAGVTPTKCLIVASLTLNTITSVLAATASIMGVVSVAVGSQFPFRYNYTITKGLDVLMLIFNMLEFCLAVSVSAFGCEASCCNSREVLVVLPSNPVETVMAPPMTLQPLLPSEHQGTNVPGNVYKNHPGEIV

Target ORF information:

RefSeq Version	XM_030251019.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus membrane-spanning 4-domains, subfamily A, member 4B (Ms4a4b), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030251019.1

ORF Insert Sequence:

ATGCAAGGAC AGGAACAGAC CACCATGGCA GTGGTTCCTG GAGTTGCTGT GCCTTCAAAG 
AATTCTGTTA TGACATCACA AATGTGGAAT GAGAAGAAAG AGAAATTCTT GAAGGGGGAA 
CCCAAAGTCC TTGGGGTTTT ACAAGTGATG ATTGCTATCA TAAACCTCAG CTTAGGAATA 
ATAATTTTGA CAACTTTATT TTCTGAACTA CCCACTTCAG TGATGTTAAT GGTCCCAATT 
TGGGGATCAA TAATGTTCAT TGTCTCCGGA TCCCTGTCCA TTGCAGCAGG AGTGACACCT 
ACAAAATGCC TGATCGTTGC CAGTCTAACT CTGAACACTA TCACCTCTGT GTTGGCTGCA 
ACTGCAAGCA TAATGGGTGT AGTCAGTGTG GCTGTGGGTT CACAGTTTCC GTTTCGGTAT 
AATTATACAA TCACCAAGGG TTTGGATGTT TTGATGTTAA TTTTCAATAT GCTAGAATTC 
TGCCTTGCTG TGTCCGTCTC TGCATTTGGA TGTGAAGCTT CCTGTTGTAA CTCCCGTGAG 
GTTCTTGTAG TGCTACCATC AAATCCTGTT GAGACAGTGA TGGCACCCCC AATGACACTT 
CAACCATTGC TACCATCAGA ACACCAAGGG ACCAATGTTC CAGGAAATGT GTACAAGAAC 
CACCCAGGAG AAATAGTCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Anti-MS4a4B treatment abrogates MS4a4B-mediated protection in T cells and ameliorates experimental autoimmune encephalomyelitis.
Apoptosis : an international journal on programmed cell death18(9)1106-19(2013 Sep)
Yan Y,Li Z,Zhang GX,Williams MS,Carey GB,Zhang J,Rostami A,Xu H

TCR stimulation upregulates MS4a4B expression through induction of AP-1 transcription factor during T cell activation.
Molecular immunology52(2)71-8(2012 Sep)
Yan Y,Zhang GX,Williams MS,Carey GB,Li H,Yang J,Rostami A,Xu H

MS4a4B, a CD20 homologue in T cells, inhibits T cell propagation by modulation of cell cycle.
PloS one5(11)e13780(2010 Nov)
Xu H,Yan Y,Williams MS,Carey GB,Yang J,Li H,Zhang GX,Rostami A

A mouse knockout library for secreted and transmembrane proteins.
Nature biotechnology28(7)749-55(2010 Jul)
Tang T,Li L,Tang J,Li Y,Lin WY,Martin F,Grant D,Solloway M,Parker L,Ye W,Forrest W,Ghilardi N,Oravecz T,Platt KA,Rice DS,Hansen GM,Abuin A,Eberhart DE,Godowski P,Holt KH,Peterson A,Zambrowicz BP,de Sauvage FJ

MS4A4B is a GITR-associated membrane adapter, expressed by regulatory T cells, which modulates T cell activation.
Journal of immunology (Baltimore, Md. : 1950)183(7)4197-204(2009 Oct)
Howie D,Nolan KF,Daley S,Butterfield E,Adams E,Garcia-Rueda H,Thompson C,Saunders NJ,Cobbold SP,Tone Y,Tone M,Waldmann H

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Ms4a4b cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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