Rhox4b cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Rhox4b
Entrez Gene ID	57737
Full Name	reproductive homeobox 4B
Synonyms	5430432L21Rik,Ehox,Rhox4.2,Rhox4a
General protein information	Preferred Names reproductive homeobox 4B Names reproductive homeobox 4B ES cell derived homeobox containing homeobox protein EHOX reproductive homeobox on X chromosome 4
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: X Map Location: X\|X A3.3

mRNA and Protein(s)

mRNA	Protein	Name
NM_021300.2	NP_067275.1	reproductive homeobox 4B

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Rhox4a	NP_001034777.1
Mus musculus (house mouse)	Rhox4c	NP_001034778.1
Mus musculus (house mouse)	Rhox4f	NP_001034785.1
Rattus norvegicus (Norway rat)	Rhox4g	NP_001020060.1
Mus musculus (house mouse)	Rhox4e	NP_957688.2
Mus musculus (house mouse)	Gm21098	XP_003689019.1
Mus musculus (house mouse)	Rhox4d	NP_001034784.1
Mus musculus (house mouse)	Rhox4b	NP_067275.1
Mus musculus (house mouse)	Rhox4g	NP_001034787.1

Gene Ontology
Bibliography

Related articles in PubMed

Specification of jaw identity by the Hand2 transcription factor.
Funato N, Kokubo H, Nakamura M, Yanagisawa H, Saga Y
Scientific reports628405(2016 Jun)

A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JLR, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A, Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR
Neuron83(2)309-323(2014 Jul)

Cell-cell adhesion defects in Mrj mutant trophoblast cells are associated with failure to pattern the chorion during early placental development.
Watson ED, Hughes M, Simmons DG, Natale DR, Sutherland AE, Cross JC
Developmental dynamics : an official publication of the American Association of Anatomists240(11)2505-19(2011 Nov)

Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus.
Chung YC, Tsai YJ, Shiu TY, Sun YY, Wang PF, Chen CL
Gene expression patterns : GEP11(1-2)84-92(2011 Jan-Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Mrj(-/-) chorions at embryonic day 8.5 have expanded Rhox4b expression domains and do not form normal layers of gene expression suggesting that chorion patterning requires Mrj.
Title: Cell-cell adhesion defects in Mrj mutant trophoblast cells are associated with failure to pattern the chorion during early placental development.

These results suggest that NFY is an essential regulatory factor for Ehox transcriptional activity, which is important for the post-implantation stage of the developing embryo.
Title: Cloning and characterization of the 5'-flanking region of the Ehox gene.

Ehox is expressed in trophoblast stem cells and pharyngeal pouch endoderm
Title: Expression of a novel homeobox gene Ehox in trophoblast stem cells and pharyngeal pouch endoderm.

Results suggest that Ehox is a novel homeobox-containing gene that is essential for the earliest stages of murine ES cell differentiation.
Title: Cloning and characterization of Ehox, a novel homeobox gene essential for embryonic stem cell differentiation.

The following Rhox4b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Rhox4b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu12133	NM_021300.2 Latest version!	Mus musculus reproductive homeobox 4B (Rhox4b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Rhox4b ( NM_021300.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_067275.1 Mus musculus reproductive homeobox 4B (Rhox4b), mRNA.

Price & Availability↑

CloneID	OMu12133
Clone ID Related Accession (Same CDS sequence)	NM_021300.2
Accession Version	NM_021300.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 618bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-10-06
Organism	Mus musculus(house mouse)
Product	reproductive homeobox 4B
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AJ972666.1. On Mar 7, 2006 this sequence version replaced NM_021300.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ972666.1, AF265350.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164134, SAMN01164137 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGCATC AAAACACCAA CTACCTACTT CATGAGGGAC TTGGCAAGGA CAAGGAAAAG 
TTGAATGGTG GGAAGACACA GACAGTCTTA CCACTGGATG GAGAGGGAAG AAATGAGGGA 
GAGAGTGTAC TGGGCCAGTC CGGAGCCGCA GCAGTGGAAT GGGACAAAGC AGAAGAATTA 
AGTGGAGAAG GTGGGCCTGC TGCTGGTGAT GCAGACCTCA TGGATAACAG CAACCAAGAG 
GACCAGGACA CCAGTGGCAG TGCCCAGGAG GAGGAGAAGC TGCCAGAGGA GCCAGTTCTC 
AGGGATGCTG TGGTCATAGA CAAAGTGCAG CCTATTCCAG TGCTGGTATC TGGTGTGCGG 
CCTAAGTCAG TGTGGGTACA GCAGCGTAGC TTACACTACA ATTTCCAATG GTGGCAGCTG 
CAGGAGCTGG AGCGCATTTT CCAGCAGAAT CACTTCATCC GTGCAGAGGA AAGAAGACAT 
CTGGCAAGAT GGATAGGTGT GAGTGAAGCC AGAGTTATGA CATGGTTTAA GAAGAGGAGA 
GAGCACTTCA GAAGAGGACA AAGTCAGTTA GGAATGAATG ATGATGCCCC TGTGGGGTCC 
CACTCTACCT TTCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_067275.1
CDS	132..749
Translation	MEHQNTNYLLHEGLGKDKEKLNGGKTQTVLPLDGEGRNEGESVLGQSGAAAVEWDKAEELSGEGGPAAGDADLMDNSNQEDQDTSGSAQEEEKLPEEPVLRDAVVIDKVQPIPVLVSGVRPKSVWVQQRSLHYNFQWWQLQELERIFQQNHFIRAEERRHLARWIGVSEARVMTWFKKRREHFRRGQSQLGMNDDAPVGSHSTFL

Target ORF information:

RefSeq Version	NM_021300.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus reproductive homeobox 4B (Rhox4b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021300.2

ORF Insert Sequence:

ATGGAGCATC AAAACACCAA CTACCTACTT CATGAGGGAC TTGGCAAGGA CAAGGAAAAG 
TTGAATGGTG GGAAGACACA GACAGTCTTA CCACTGGATG GAGAGGGAAG AAATGAGGGA 
GAGAGTGTAC TGGGCCAGTC CGGAGCCGCA GCAGTGGAAT GGGACAAAGC AGAAGAATTA 
AGTGGAGAAG GTGGGCCTGC TGCTGGTGAT GCAGACCTCA TGGATAACAG CAACCAAGAG 
GACCAGGACA CCAGTGGCAG TGCCCAGGAG GAGGAGAAGC TGCCAGAGGA GCCAGTTCTC 
AGGGATGCTG TGGTCATAGA CAAAGTGCAG CCTATTCCAG TGCTGGTATC TGGTGTGCGG 
CCTAAGTCAG TGTGGGTACA GCAGCGTAGC TTACACTACA ATTTCCAATG GTGGCAGCTG 
CAGGAGCTGG AGCGCATTTT CCAGCAGAAT CACTTCATCC GTGCAGAGGA AAGAAGACAT 
CTGGCAAGAT GGATAGGTGT GAGTGAAGCC AGAGTTATGA CATGGTTTAA GAAGAGGAGA 
GAGCACTTCA GAAGAGGACA AAGTCAGTTA GGAATGAATG ATGATGCCCC TGTGGGGTCC 
CACTCTACCT TTCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Specification of jaw identity by the Hand2 transcription factor.
Scientific reports628405(2016 Jun)
Funato N,Kokubo H,Nakamura M,Yanagisawa H,Saga Y

A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Neuron83(2)309-323(2014 Jul)
Thompson CL,Ng L,Menon V,Martinez S,Lee CK,Glattfelder K,Sunkin SM,Henry A,Lau C,Dang C,Garcia-Lopez R,Martinez-Ferre A,Pombero A,Rubenstein JLR,Wakeman WB,Hohmann J,Dee N,Sodt AJ,Young R,Smith K,Nguyen TN,Kidney J,Kuan L,Jeromin A,Kaykas A,Miller J,Page D,Orta G,Bernard A,Riley Z,Smith S,Wohnoutka P,Hawrylycz MJ,Puelles L,Jones AR

Cell-cell adhesion defects in Mrj mutant trophoblast cells are associated with failure to pattern the chorion during early placental development.
Developmental dynamics : an official publication of the American Association of Anatomists240(11)2505-19(2011 Nov)
Watson ED,Hughes M,Simmons DG,Natale DR,Sutherland AE,Cross JC

Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus.
Gene expression patterns : GEP11(1-2)84-92(2011 Jan-Feb)
Chung YC,Tsai YJ,Shiu TY,Sun YY,Wang PF,Chen CL

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Rhox4b cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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