Fads2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Fads2
Entrez Gene ID	56473
Full Name	fatty acid desaturase 2
Synonyms	2900042M13Rik,Fadsd2
General protein information	Preferred Names fatty acid desaturase 2 Names fatty acid desaturase 2 D6D delta(6) desaturase delta(6) fatty acid desaturase
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 19 Map Location: 19\|19 A

mRNA and Protein(s)

mRNA	Protein	Name
NM_019699.1	NP_062673.1	acyl-CoA 6-desaturase
NM_019699.2	NP_062673.1	acyl-CoA 6-desaturase

Pathways from BioSystems

Homologies

Caenorhabditis elegans (roundworm)	fat-3	NP_001255426.1
Caenorhabditis elegans (roundworm)	fat-4	NP_001255423.1
Mus musculus (house mouse)	Fads2	NP_062673.1
Danio rerio (zebrafish)	fads2	NP_571720.2
Homo sapiens (human)	FADS2	NP_004256.1
Pan troglodytes (chimpanzee)	FADS2	XP_508482.2
Rattus norvegicus (Norway rat)	Fads2	NP_112634.1
Gallus gallus (chicken)	FADS2	NP_001153900.1
Xenopus tropicalis (tropical clawed frog)	fads2	NP_001120262.1
	FADS2	XP_001116629.1
Canis lupus familiaris (dog)	FADS2	XP_005631707.1
Bos taurus (cattle)	FADS2	NP_001076913.1

Gene Ontology
Bibliography

Related articles in PubMed

Increasing dietary EPA and DHA influence estimated fatty acid desaturase activity in systemic organs which is reflected in the red blood cell in mice.
Davidson EA, Pickens CA, Fenton JI
International journal of food sciences and nutrition69(2)183-191(2018 Mar)

FADS2 inhibition in essential fatty acid deficiency induces hepatic lipid accumulation via impairment of very low-density lipoprotein (VLDL) secretion.
Hayashi Y, Shimamura A, Ishikawa T, Fujiwara Y, Ichi I
Biochemical and biophysical research communications(2018 Jan)

Neither linoleic acid nor arachidonic acid promote white adipose tissue inflammation in Fads2-/- mice fed low fat diets.
Suitor K, Payne GW, Sarr O, Abdelmagid S, Nakamura MT, Ma DW, Mutch DM
Prostaglandins, leukotrienes, and essential fatty acids12684-91(2017 Nov)

Lsd1 Ablation Triggers Metabolic Reprogramming of Brown Adipose Tissue.
Duteil D, Tosic M, Lausecker F, Nenseth HZ, M?ller JM, Urban S, Willmann D, Petroll K, Messaddeq N, Arrigoni L, Manke T, Kornfeld JW, Br?ning JC, Zagoriy V, Meret M, Dengjel J, Kanouni T, Sch?le R
Cell reports17(4)1008-1021(2016 10)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

differential PUFA profiles between HET mice and human FADS SNPs suggest low expression of both FADS1 and 2 genes in human minor haplotypes.
Title: Compensatory induction of Fads1 gene expression in heterozygous Fads2-null mice and by diet with a high n-6/n-3 PUFA ratio.

Data (including data from studies using knockout mice) suggest that immunomodulatory effects of dietary omega-6 vs. omega-3 fatty acids are due, in part, to interconversion of the various unsaturated fatty acids consumed/administered; thus, delta-6 desaturase plays role in immunomodulatory effects of dietary unsaturated fatty acids.
Title: The delta 6 desaturase knock out mouse reveals that immunomodulatory effects of essential n-6 and n-3 polyunsaturated fatty acids are both independent of and dependent upon conversion.

knockdown of Elovl5, Fads1, or Fads2 decreased the level of Mead acid.
Title: Identification of genes and pathways involved in the synthesis of Mead acid (20:3n-9), an indicator of essential fatty acid deficiency.

FADS2 deficient mice are obesity resistant.
Title: Obesity resistance and deregulation of lipogenesis in ?6-fatty acid desaturase (FADS2) deficiency.

Using a sample of 534 twins, study observed a trend in the moderation of brain fatty acid effects on IQ by FADS2 variation. Using of publicly available gene expression databases from both humans and mice, showed that FADS2 variants also correlate with FADS1 brain expression
Title: FADS2 Genetic Variance in Combination with Fatty Acid Intake Might Alter Composition of the Fatty Acids in Brain.

The following Fads2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Fads2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu11558	NM_019699.2 Latest version!	Mus musculus fatty acid desaturase 2 (Fads2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
View Old Accession Versions >>
OMu11558	NM_019699.1	Mus musculus fatty acid desaturase 2 (Fads2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Fads2 ( NM_019699.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_062673.1 Mus musculus fatty acid desaturase 2 (Fads2), mRNA.

Price & Availability↑

CloneID	OMu11558
Clone ID Related Accession (Same CDS sequence)	NM_019699.1 , NM_019699.2
Accession Version	NM_019699.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1335bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-15
Organism	Mus musculus(house mouse)
Product	acyl-CoA 6-desaturase
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF126798.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF126798.1, SRR1660817.269453.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN00849386 [ECO:0000348] ##Evidence-Data-END##

ATGGGGAAGG GAGGTAACCA GGGAGAGGGG AGCACCGAGC GCCAGGCTCC GATGCCCACC 
TTCCGTTGGG AGGAGATTCA GAAGCACAAC CTGCGCACCG ACCGGTGGCT CGTCATCGAC 
CGCAAGGTCT ACAACGTTAC CAAATGGTCC CAGCGGCACC CGGGGGGCCA CCGTGTCATC 
GGACACTATT CGGGAGAAGA TGCTACGGAT GCCTTCCGTG CCTTCCATCT GGACCTGGAC 
TTCGTGGGCA AGTTCTTGAA GCCCCTGCTG ATTGGTGAGC TGGCCCCAGA GGAGCCCAGC 
CTGGACCGTG GCAAAAGCTC TCAGATCACC GAGGACTTCA GGGCCCTGAA GAAGACTGCT 
GAGGACATGA ACCTCTTCAA AACCAACCAC CTGTTCTTCT TTCTCCTCCT GTCCCACATC 
ATCGTCATGG AAAGCCTTGC CTGGTTCATC CTCTCGTACT TCGGCACTGG CTGGATTCCT 
ACCCTCGTCA CAGCCTTTGT CCTCGCTACC TCTCAGGCCC AAGCTGGATG GCTGCAACAT 
GACTATGGCC ACCTTTCTGT CTATAAGAAA TCCATATGGA ACCACGTTGT CCACAAGTTT 
GTCATTGGCC ACTTAAAGGG TGCCTCAGCC AACTGGTGGA ACCACCGACA TTTCCAACAC 
CATGCCAAGC CCAACATCTT CCACAAGGAC CCGGACATAA AGAGCCTGCA TGTGTTTGTC 
CTTGGCGAGT GGCAGCCCCT TGAGTATGGC AAGAAGAAGC TGAAATACCT GCCCTACAAC 
CACCAGCATG AATACTTCTT CCTGATCGGA CCGCCGCTGC TCATCCCTAT GTACTTCCAG 
TACCAGATCA TCATGACAAT GATCAGCCGC AGGGACTGGG TGGACTTGGC TTGGGCCATC 
AGCTACTATA TGCGTTTCTT CTACACCTAC ATCCCTTTCT ACGGCATCTT GGGAGCCCTG 
GTTTTCCTCA ACTTTATCAG GTTCCTGGAG AGCCACTGGT TTGTGTGGGT CACACAGATG 
AACCACCTTG TCATGGAGAT TGATCTTGAT CACTACCGGG ACTGGTTCAG CAGCCAGCTG 
GCAGCCACCT GCAATGTGGA GCAGTCCTTC TTCAATGACT GGTTCAGCGG GCACCTCAAT 
TTCCAGATTG AGCACCACCT CTTCCCCACT ATGCCACGTC ACAACCTGCA CAAGATTGCC 
CCACTGGTGA AGTCTCTCTG CGCCAAGCAT GGCATTGAAT ACCAGGAGAA GCCGTTGCTG 
AGGGCCCTGA TCGACATTGT GAGTTCACTG AAGAAGTCTG GGGAGCTGTG GCTGGATGCT 
TACCTCCATA AATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_062673.1
CDS	75..1409
Translation	MGKGGNQGEGSTERQAPMPTFRWEEIQKHNLRTDRWLVIDRKVYNVTKWSQRHPGGHRVIGHYSGEDATDAFRAFHLDLDFVGKFLKPLLIGELAPEEPSLDRGKSSQITEDFRALKKTAEDMNLFKTNHLFFFLLLSHIIVMESLAWFILSYFGTGWIPTLVTAFVLATSQAQAGWLQHDYGHLSVYKKSIWNHVVHKFVIGHLKGASANWWNHRHFQHHAKPNIFHKDPDIKSLHVFVLGEWQPLEYGKKKLKYLPYNHQHEYFFLIGPPLLIPMYFQYQIIMTMISRRDWVDLAWAISYYMRFFYTYIPFYGILGALVFLNFIRFLESHWFVWVTQMNHLVMEIDLDHYRDWFSSQLAATCNVEQSFFNDWFSGHLNFQIEHHLFPTMPRHNLHKIAPLVKSLCAKHGIEYQEKPLLRALIDIVSSLKKSGELWLDAYLHK

Target ORF information:

RefSeq Version	NM_019699.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus fatty acid desaturase 2 (Fads2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019699.1

ORF Insert Sequence:

ATGGGGAAGG GAGGTAACCA GGGAGAGGGG AGCACCGAGC GCCAGGCTCC GATGCCCACC 
TTCCGTTGGG AGGAGATTCA GAAGCACAAC CTGCGCACCG ACCGGTGGCT CGTCATCGAC 
CGCAAGGTCT ACAACGTTAC CAAATGGTCC CAGCGGCACC CGGGGGGCCA CCGTGTCATC 
GGACACTATT CGGGAGAAGA TGCTACGGAT GCCTTCCGTG CCTTCCATCT GGACCTGGAC 
TTCGTGGGCA AGTTCTTGAA GCCCCTGCTG ATTGGTGAGC TGGCCCCAGA GGAGCCCAGC 
CTGGACCGTG GCAAAAGCTC TCAGATCACC GAGGACTTCA GGGCCCTGAA GAAGACTGCT 
GAGGACATGA ACCTCTTCAA AACCAACCAC CTGTTCTTCT TTCTCCTCCT GTCCCACATC 
ATCGTCATGG AAAGCCTTGC CTGGTTCATC CTCTCGTACT TCGGCACTGG CTGGATTCCT 
ACCCTCGTCA CAGCCTTTGT CCTCGCTACC TCTCAGGCCC AAGCTGGATG GCTGCAACAT 
GACTATGGCC ACCTTTCTGT CTATAAGAAA TCCATATGGA ACCACGTTGT CCACAAGTTT 
GTCATTGGCC ACTTAAAGGG TGCCTCAGCC AACTGGTGGA ACCACCGACA TTTCCAACAC 
CATGCCAAGC CCAACATCTT CCACAAGGAC CCGGACATAA AGAGCCTGCA TGTGTTTGTC 
CTTGGCGAGT GGCAGCCCCT TGAGTATGGC AAGAAGAAGC TGAAATACCT GCCCTACAAC 
CACCAGCATG AATACTTCTT CCTGATCGGA CCGCCGCTGC TCATCCCTAT GTACTTCCAG 
TACCAGATCA TCATGACAAT GATCAGCCGC AGGGACTGGG TGGACTTGGC TTGGGCCATC 
AGCTACTATA TGCGTTTCTT CTACACCTAC ATCCCTTTCT ACGGCATCTT GGGAGCCCTG 
GTTTTCCTCA ACTTTATCAG GTTCCTGGAG AGCCACTGGT TTGTGTGGGT CACACAGATG 
AACCACCTTG TCATGGAGAT TGATCTTGAT CACTACCGGG ACTGGTTCAG CAGCCAGCTG 
GCAGCCACCT GCAATGTGGA GCAGTCCTTC TTCAATGACT GGTTCAGCGG GCACCTCAAT 
TTCCAGATTG AGCACCACCT CTTCCCCACT ATGCCACGTC ACAACCTGCA CAAGATTGCC 
CCACTGGTGA AGTCTCTCTG CGCCAAGCAT GGCATTGAAT ACCAGGAGAA GCCGTTGCTG 
AGGGCCCTGA TCGACATTGT GAGTTCACTG AAGAAGTCTG GGGAGCTGTG GCTGGATGCT 
TACCTCCATA AATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Fads2 ( NM_019699.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_062673.1 Mus musculus fatty acid desaturase 2 (Fads2), mRNA.

Price & Availability↑

CloneID	OMu11558
Clone ID Related Accession (Same CDS sequence)	NM_019699.1 , NM_019699.2
Accession Version	NM_019699.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1335bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-31
Organism	Mus musculus(house mouse)
Product	acyl-CoA 6-desaturase
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC135670.3. On Feb 8, 2019 this sequence version replaced NM_019699.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR7345562.3294743.1, SRR7345562.1617999.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN00849386 [ECO:0000348] ##Evidence-Data-END##

ATGGGGAAGG GAGGTAACCA GGGAGAGGGG AGCACCGAGC GCCAGGCTCC GATGCCCACC 
TTCCGTTGGG AGGAGATTCA GAAGCACAAC CTGCGCACCG ACCGGTGGCT CGTCATCGAC 
CGCAAGGTCT ACAACGTTAC CAAATGGTCC CAGCGGCACC CGGGGGGCCA CCGTGTCATC 
GGACACTATT CGGGAGAAGA TGCTACGGAT GCCTTCCGTG CCTTCCATCT GGACCTGGAC 
TTCGTGGGCA AGTTCTTGAA GCCCCTGCTG ATTGGTGAGC TGGCCCCAGA GGAGCCCAGC 
CTGGACCGTG GCAAAAGCTC TCAGATCACC GAGGACTTCA GGGCCCTGAA GAAGACTGCT 
GAGGACATGA ACCTCTTCAA AACCAACCAC CTGTTCTTCT TTCTCCTCCT GTCCCACATC 
ATCGTCATGG AAAGCCTTGC CTGGTTCATC CTCTCGTACT TCGGCACTGG CTGGATTCCT 
ACCCTCGTCA CAGCCTTTGT CCTCGCTACC TCTCAGGCCC AAGCTGGATG GCTGCAACAT 
GACTATGGCC ACCTTTCTGT CTATAAGAAA TCCATATGGA ACCACGTTGT CCACAAGTTT 
GTCATTGGCC ACTTAAAGGG TGCCTCAGCC AACTGGTGGA ACCACCGACA TTTCCAACAC 
CATGCCAAGC CCAACATCTT CCACAAGGAC CCGGACATAA AGAGCCTGCA TGTGTTTGTC 
CTTGGCGAGT GGCAGCCCCT TGAGTATGGC AAGAAGAAGC TGAAATACCT GCCCTACAAC 
CACCAGCATG AATACTTCTT CCTGATCGGA CCGCCGCTGC TCATCCCTAT GTACTTCCAG 
TACCAGATCA TCATGACAAT GATCAGCCGC AGGGACTGGG TGGACTTGGC TTGGGCCATC 
AGCTACTATA TGCGTTTCTT CTACACCTAC ATCCCTTTCT ACGGCATCTT GGGAGCCCTG 
GTTTTCCTCA ACTTTATCAG GTTCCTGGAG AGCCACTGGT TTGTGTGGGT CACACAGATG 
AACCACCTTG TCATGGAGAT TGATCTTGAT CACTACCGGG ACTGGTTCAG CAGCCAGCTG 
GCAGCCACCT GCAATGTGGA GCAGTCCTTC TTCAATGACT GGTTCAGCGG GCACCTCAAT 
TTCCAGATTG AGCACCACCT CTTCCCCACT ATGCCACGTC ACAACCTGCA CAAGATTGCC 
CCACTGGTGA AGTCTCTCTG CGCCAAGCAT GGCATTGAAT ACCAGGAGAA GCCGTTGCTG 
AGGGCCCTGA TCGACATTGT GAGTTCACTG AAGAAGTCTG GGGAGCTGTG GCTGGATGCT 
TACCTCCATA AATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_062673.1
CDS	75..1409
Translation	MGKGGNQGEGSTERQAPMPTFRWEEIQKHNLRTDRWLVIDRKVYNVTKWSQRHPGGHRVIGHYSGEDATDAFRAFHLDLDFVGKFLKPLLIGELAPEEPSLDRGKSSQITEDFRALKKTAEDMNLFKTNHLFFFLLLSHIIVMESLAWFILSYFGTGWIPTLVTAFVLATSQAQAGWLQHDYGHLSVYKKSIWNHVVHKFVIGHLKGASANWWNHRHFQHHAKPNIFHKDPDIKSLHVFVLGEWQPLEYGKKKLKYLPYNHQHEYFFLIGPPLLIPMYFQYQIIMTMISRRDWVDLAWAISYYMRFFYTYIPFYGILGALVFLNFIRFLESHWFVWVTQMNHLVMEIDLDHYRDWFSSQLAATCNVEQSFFNDWFSGHLNFQIEHHLFPTMPRHNLHKIAPLVKSLCAKHGIEYQEKPLLRALIDIVSSLKKSGELWLDAYLHK

Target ORF information:

RefSeq Version	NM_019699.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus fatty acid desaturase 2 (Fads2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019699.2

ORF Insert Sequence:

ATGGGGAAGG GAGGTAACCA GGGAGAGGGG AGCACCGAGC GCCAGGCTCC GATGCCCACC 
TTCCGTTGGG AGGAGATTCA GAAGCACAAC CTGCGCACCG ACCGGTGGCT CGTCATCGAC 
CGCAAGGTCT ACAACGTTAC CAAATGGTCC CAGCGGCACC CGGGGGGCCA CCGTGTCATC 
GGACACTATT CGGGAGAAGA TGCTACGGAT GCCTTCCGTG CCTTCCATCT GGACCTGGAC 
TTCGTGGGCA AGTTCTTGAA GCCCCTGCTG ATTGGTGAGC TGGCCCCAGA GGAGCCCAGC 
CTGGACCGTG GCAAAAGCTC TCAGATCACC GAGGACTTCA GGGCCCTGAA GAAGACTGCT 
GAGGACATGA ACCTCTTCAA AACCAACCAC CTGTTCTTCT TTCTCCTCCT GTCCCACATC 
ATCGTCATGG AAAGCCTTGC CTGGTTCATC CTCTCGTACT TCGGCACTGG CTGGATTCCT 
ACCCTCGTCA CAGCCTTTGT CCTCGCTACC TCTCAGGCCC AAGCTGGATG GCTGCAACAT 
GACTATGGCC ACCTTTCTGT CTATAAGAAA TCCATATGGA ACCACGTTGT CCACAAGTTT 
GTCATTGGCC ACTTAAAGGG TGCCTCAGCC AACTGGTGGA ACCACCGACA TTTCCAACAC 
CATGCCAAGC CCAACATCTT CCACAAGGAC CCGGACATAA AGAGCCTGCA TGTGTTTGTC 
CTTGGCGAGT GGCAGCCCCT TGAGTATGGC AAGAAGAAGC TGAAATACCT GCCCTACAAC 
CACCAGCATG AATACTTCTT CCTGATCGGA CCGCCGCTGC TCATCCCTAT GTACTTCCAG 
TACCAGATCA TCATGACAAT GATCAGCCGC AGGGACTGGG TGGACTTGGC TTGGGCCATC 
AGCTACTATA TGCGTTTCTT CTACACCTAC ATCCCTTTCT ACGGCATCTT GGGAGCCCTG 
GTTTTCCTCA ACTTTATCAG GTTCCTGGAG AGCCACTGGT TTGTGTGGGT CACACAGATG 
AACCACCTTG TCATGGAGAT TGATCTTGAT CACTACCGGG ACTGGTTCAG CAGCCAGCTG 
GCAGCCACCT GCAATGTGGA GCAGTCCTTC TTCAATGACT GGTTCAGCGG GCACCTCAAT 
TTCCAGATTG AGCACCACCT CTTCCCCACT ATGCCACGTC ACAACCTGCA CAAGATTGCC 
CCACTGGTGA AGTCTCTCTG CGCCAAGCAT GGCATTGAAT ACCAGGAGAA GCCGTTGCTG 
AGGGCCCTGA TCGACATTGT GAGTTCACTG AAGAAGTCTG GGGAGCTGTG GCTGGATGCT 
TACCTCCATA AATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Increasing dietary EPA and DHA influence estimated fatty acid desaturase activity in systemic organs which is reflected in the red blood cell in mice.
International journal of food sciences and nutrition69(2)183-191(2018 Mar)
Davidson EA,Pickens CA,Fenton JI

FADS2 inhibition in essential fatty acid deficiency induces hepatic lipid accumulation via impairment of very low-density lipoprotein (VLDL) secretion.
Biochemical and biophysical research communications(2018 Jan)
Hayashi Y,Shimamura A,Ishikawa T,Fujiwara Y,Ichi I

Neither linoleic acid nor arachidonic acid promote white adipose tissue inflammation in Fads2-/- mice fed low fat diets.
Prostaglandins, leukotrienes, and essential fatty acids12684-91(2017 Nov)
Suitor K,Payne GW,Sarr O,Abdelmagid S,Nakamura MT,Ma DW,Mutch DM

Lsd1 Ablation Triggers Metabolic Reprogramming of Brown Adipose Tissue.
Cell reports17(4)1008-1021(2016 10)
Duteil D,Tosic M,Lausecker F,Nenseth HZ,M?ller JM,Urban S,Willmann D,Petroll K,Messaddeq N,Arrigoni L,Manke T,Kornfeld JW,Br?ning JC,Zagoriy V,Meret M,Dengjel J,Kanouni T,Sch?le R

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Fads2 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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