Gene Symbol | Abat |
Entrez Gene ID | 268860 |
Full Name | 4-aminobutyrate aminotransferase |
Synonyms | 9630038C02Rik,AI255750,Gabaat,Gabat,Gm9851,I54,Laibat,X61497 |
General protein information |
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Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome | |
Summary | The encoded gene product is responsible for catabolism of gamma-aminobutyric acid (GABA), a mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. Deficiency of this encoded protein includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010]. |