Ttc26 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ttc26
Entrez Gene ID	264134
Full Name	tetratricopeptide repeat domain 26
Synonyms	9330141E21Rik,9430097H08Rik,Ift56,hop,hpy
General protein information	Preferred Names tetratricopeptide repeat domain 26 Names intraflagellar transport protein 56 TPR repeat protein 26 hydrocephalic-polydactyl protein hop-sterile tetratricopeptide repeat protein 26
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 6 Map Location: 6\|6 B1

mRNA and Protein(s)

mRNA	Protein	Name
NM_153600.2	NP_705828.2	intraflagellar transport protein 56
XM_006506152.3	XP_006506215.1	intraflagellar transport protein 56 isoform X1
XM_006506152.4	XP_006506215.1	intraflagellar transport protein 56 isoform X1

Pathways from BioSystems

Homologies

	LOC715688	XP_001106020.2
Gallus gallus (chicken)	TTC26	XP_004937740.1
Bos taurus (cattle)	TTC26	XP_002687045.1
Drosophila melanogaster (fruit fly)	CG4525	NP_650486.1
Caenorhabditis elegans (roundworm)	dyf-13	NP_741021.1
Homo sapiens (human)	TTC26	NP_079202.2
Pan troglodytes (chimpanzee)	TTC26	XP_527905.3
Rattus norvegicus (Norway rat)	Ttc26	NP_001020216.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001809	XP_321248.5
Canis lupus familiaris (dog)	TTC26	XP_003639595.2
Mus musculus (house mouse)	Ttc26	NP_705828.2
Danio rerio (zebrafish)	ttc26	NP_001008617.1
Xenopus tropicalis (tropical clawed frog)	ttc26	NP_001096401.1

Gene Ontology
Bibliography

Related articles in PubMed

IFT56 regulates vertebrate developmental patterning by maintaining IFTB complex integrity and ciliary microtubule architecture.
Xin D, Christopher KJ, Zeng L, Kong Y, Weatherbee SD
Development (Cambridge, England)144(8)1544-1553(2017 04)

A mutation in the mouse ttc26 gene leads to impaired hedgehog signaling.
Swiderski RE, Nakano Y, Mullins RF, Seo S, B?nfi B
PLoS genetics10(10)e1004689(2014 Oct)

TTC26/DYF13 is an intraflagellar transport protein required for transport of motility-related proteins into flagella.
Ishikawa H, Ide T, Yagi T, Jiang X, Hirono M, Sasaki H, Yanagisawa H, Wemmer KA, Stainier DY, Qin H, Kamiya R, Marshall WF
eLife3e01566(2014 Jan)

Knockdown of ttc26 disrupts ciliogenesis of the photoreceptor cells and the pronephros in zebrafish.
Zhang Q, Liu Q, Austin C, Drummond I, Pierce EA
Molecular biology of the cell23(16)3069-78(2012 Aug)

Characterization of mouse IFT complex B.
Follit JA, Xu F, Keady BT, Pazour GJ
Cell motility and the cytoskeleton66(8)457-68(2009 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These studies define a distinct and novel role for IFT56 in IFTB complex integrity that is crucial for cilia structure and function and, ultimately, animal development.
Title: IFT56 regulates vertebrate developmental patterning by maintaining IFTB complex integrity and ciliary microtubule architecture.

Our analysis of the hop mouse line provides novel insights into Hh signaling, demonstrating that Ttc26 is necessary for efficient coupling between the accumulation of Gli at the ciliary tip and its dissociation from Sufu.
Title: A mutation in the mouse ttc26 gene leads to impaired hedgehog signaling.

TTC26 is an intraflagellar transport protein required for transport of motility-related proteins into flagella.
Title: TTC26/DYF13 is an intraflagellar transport protein required for transport of motility-related proteins into flagella.

Data show that Hop is expressed in airway epithelium coincident with HDAC2, and acts downstream of Nkx2.1 and GATA6, to negatively regulate surfactant protein expression.
Title: Hop functions downstream of Nkx2.1 and GATA6 to mediate HDAC-dependent negative regulation of pulmonary gene expression.

The following Ttc26 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ttc26 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu02963	NM_153600.2 Latest version!	Mus musculus tetratricopeptide repeat domain 26 (Ttc26), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
OMu37284	XM_006506152.4 Latest version!	Mus musculus tetratricopeptide repeat domain 26 (Ttc26), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
View Old Accession Versions >>
OMu37284	XM_006506152.3	Mus musculus tetratricopeptide repeat domain 26 (Ttc26), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ttc26 ( XM_006506152.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006506215.1 Mus musculus tetratricopeptide repeat domain 26 (Ttc26), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu37284
Clone ID Related Accession (Same CDS sequence)	XM_006506152.3 , XM_006506152.4
Accession Version	XM_006506152.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1557bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	intraflagellar transport protein 56 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000072.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006506152.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATGCTTT CAAGGGCCAA ACCCGCTGTG GGCGGGGAGT CACCGCACAC TGACAAAAGA 
AAGAAGAAAG GGAGGAAGAT TCCAAAACTA GAGGATCTAC TTTCGCAGAG AGATTTCACT 
GGCGCCATTA CCCTATTGGA GTTCAAGCGC CACGTTGGGG AGCAAGAAGA CGACACTAAC 
TTATGGATTG GATACTGTGC TTTTCACCTG GGTGACTACA AGAGAGCTTT GGAGGAATAT 
GAAAATGCAA CGAAGGAGGA AAATTGCAAT CCAGAAGTGT GGGTGAACTT GGCCTGCACC 
TACTTTTTTC TTGGGATGTA TAAACAAGCA GAAGCTGCTG GGTTTAAAGC TCCAAAAAGC 
CGGCTCCAAA ACCGCCTACT GTTCCATCTG GCTCACAAGT TTAATGATGA GAAGAAATTA 
ATGAACTTTC ATCAGAATCT TCAGGATATC AAGGAAGACC AGCTTAGTTT GGCCTCAATC 
CACTACATGC GATCCCATTA CCAAGAAGCT ATTGATATAT ACAAGCGGAT CCTGCTGGAC 
AACAGGGAAT ACCTGGCCCT CAATGTGTAT GTGGCCCTCT GCTACTACAA ACTGGATTAC 
TATGATGTGT CTCAAGAAGT CCTGGCTGTT TACCTTCAGC AGATTCCTGA CAGTACCATC 
GCCCTCAACC TTAAGGCCTG CAATCACTTT CGCCTTTATA ACGGCAAAGC AGCTGAGGCA 
GAGCTCAAAA GCTTGATGGA CAATGCATCT TCACCCTTTG AATTTGCTAA AGAACTCATC 
AGGCACAATC TGGTTGTTTT CCGAGGAGGC GAAGGGGCTT TGCAGGTTTT ACCTCCCCTG 
GTTGATGTCA TTCCTGAAGC TAGGCTCAAC CTAGTGATTT ACTACCTTCG TCAAGATGAT 
GTGCAGGAAG CCTATAATTT AATCAAGGAT TTGGAACCCA CTACACCTCA GGAGTATATC 
CTCAAGGGAG TTGTCAATGC AGCCCTTGGC CAGGAAATGG GTTCAAGGGA TCATATGAAA 
ATTGCCCAGC AGTTTTTCCA GTTGGTAGGA GGATCAGCTA GTGAATGTGA TACAATACCA 
GGAAGGCAGT GCATGGCTTC CTGTTTCTTC CTACTTAAAC AATTTGATGA TGTCTTGATT 
TACCTCAACT CTTTTAAGAG TTACTTCTAT AATGATGACA TCTTTAACTT TAATTATGCC 
CAAGCCAAAG CTGCAACAGG CAATACCAGT GAGGGTGAAG AGGTTTTCCT CTTGATCCAA 
AGTGAGAAAC TGAAAAATGA CTACATTTAC CTTAGCTGGT TAGCTCGCTG CTATATTATG 
AATAAGAAAC CAAGACTAGC TTGGGAGCTT TATCTCAAGA TGGAAACCTC TGGCGAGTCC 
TTCAGCCTCT TACAGCTCAT TGCCAATGAC TGTTACAAGA TGGGCCAGTT CTACTATTCA 
GCCAAAGCTT TTGATGTCTT AGAAAGACTG GATCCCAACC CTGAGTACTG GGAAGGCAAG 
AGGGGTGCCT GTGTGGGCAT CTTCCAGATG ATCTTAGCTG GGAGAGAACC CAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006506215.1
CDS	118..1674
Translation	MMLSRAKPAVGGESPHTDKRKKKGRKIPKLEDLLSQRDFTGAITLLEFKRHVGEQEDDTNLWIGYCAFHLGDYKRALEEYENATKEENCNPEVWVNLACTYFFLGMYKQAEAAGFKAPKSRLQNRLLFHLAHKFNDEKKLMNFHQNLQDIKEDQLSLASIHYMRSHYQEAIDIYKRILLDNREYLALNVYVALCYYKLDYYDVSQEVLAVYLQQIPDSTIALNLKACNHFRLYNGKAAEAELKSLMDNASSPFEFAKELIRHNLVVFRGGEGALQVLPPLVDVIPEARLNLVIYYLRQDDVQEAYNLIKDLEPTTPQEYILKGVVNAALGQEMGSRDHMKIAQQFFQLVGGSASECDTIPGRQCMASCFFLLKQFDDVLIYLNSFKSYFYNDDIFNFNYAQAKAATGNTSEGEEVFLLIQSEKLKNDYIYLSWLARCYIMNKKPRLAWELYLKMETSGESFSLLQLIANDCYKMGQFYYSAKAFDVLERLDPNPEYWEGKRGACVGIFQMILAGREPK

Target ORF information:

RefSeq Version	XM_006506152.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus tetratricopeptide repeat domain 26 (Ttc26), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006506152.3

ORF Insert Sequence:

ATGATGCTTT CAAGGGCCAA ACCCGCTGTG GGCGGGGAGT CACCGCACAC TGACAAAAGA 
AAGAAGAAAG GGAGGAAGAT TCCAAAACTA GAGGATCTAC TTTCGCAGAG AGATTTCACT 
GGCGCCATTA CCCTATTGGA GTTCAAGCGC CACGTTGGGG AGCAAGAAGA CGACACTAAC 
TTATGGATTG GATACTGTGC TTTTCACCTG GGTGACTACA AGAGAGCTTT GGAGGAATAT 
GAAAATGCAA CGAAGGAGGA AAATTGCAAT CCAGAAGTGT GGGTGAACTT GGCCTGCACC 
TACTTTTTTC TTGGGATGTA TAAACAAGCA GAAGCTGCTG GGTTTAAAGC TCCAAAAAGC 
CGGCTCCAAA ACCGCCTACT GTTCCATCTG GCTCACAAGT TTAATGATGA GAAGAAATTA 
ATGAACTTTC ATCAGAATCT TCAGGATATC AAGGAAGACC AGCTTAGTTT GGCCTCAATC 
CACTACATGC GATCCCATTA CCAAGAAGCT ATTGATATAT ACAAGCGGAT CCTGCTGGAC 
AACAGGGAAT ACCTGGCCCT CAATGTGTAT GTGGCCCTCT GCTACTACAA ACTGGATTAC 
TATGATGTGT CTCAAGAAGT CCTGGCTGTT TACCTTCAGC AGATTCCTGA CAGTACCATC 
GCCCTCAACC TTAAGGCCTG CAATCACTTT CGCCTTTATA ACGGCAAAGC AGCTGAGGCA 
GAGCTCAAAA GCTTGATGGA CAATGCATCT TCACCCTTTG AATTTGCTAA AGAACTCATC 
AGGCACAATC TGGTTGTTTT CCGAGGAGGC GAAGGGGCTT TGCAGGTTTT ACCTCCCCTG 
GTTGATGTCA TTCCTGAAGC TAGGCTCAAC CTAGTGATTT ACTACCTTCG TCAAGATGAT 
GTGCAGGAAG CCTATAATTT AATCAAGGAT TTGGAACCCA CTACACCTCA GGAGTATATC 
CTCAAGGGAG TTGTCAATGC AGCCCTTGGC CAGGAAATGG GTTCAAGGGA TCATATGAAA 
ATTGCCCAGC AGTTTTTCCA GTTGGTAGGA GGATCAGCTA GTGAATGTGA TACAATACCA 
GGAAGGCAGT GCATGGCTTC CTGTTTCTTC CTACTTAAAC AATTTGATGA TGTCTTGATT 
TACCTCAACT CTTTTAAGAG TTACTTCTAT AATGATGACA TCTTTAACTT TAATTATGCC 
CAAGCCAAAG CTGCAACAGG CAATACCAGT GAGGGTGAAG AGGTTTTCCT CTTGATCCAA 
AGTGAGAAAC TGAAAAATGA CTACATTTAC CTTAGCTGGT TAGCTCGCTG CTATATTATG 
AATAAGAAAC CAAGACTAGC TTGGGAGCTT TATCTCAAGA TGGAAACCTC TGGCGAGTCC 
TTCAGCCTCT TACAGCTCAT TGCCAATGAC TGTTACAAGA TGGGCCAGTT CTACTATTCA 
GCCAAAGCTT TTGATGTCTT AGAAAGACTG GATCCCAACC CTGAGTACTG GGAAGGCAAG 
AGGGGTGCCT GTGTGGGCAT CTTCCAGATG ATCTTAGCTG GGAGAGAACC CAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ttc26 ( NM_153600.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_705828.2 Mus musculus tetratricopeptide repeat domain 26 (Ttc26), mRNA.

Price & Availability↑

CloneID	OMu02963
Clone ID Related Accession (Same CDS sequence)	NM_153600.2
Accession Version	NM_153600.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1665bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Mus musculus(house mouse)
Product	intraflagellar transport protein 56
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC066060.1. On Feb 22, 2004 this sequence version replaced NM_153600.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC066060.1, AK035185.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849384, SAMN00849385 [ECO:0000348] ##Evidence-Data-END##

ATGATGCTTT CAAGGGCCAA ACCCGCTGTG GGCGGGGAGT CACCGCACAC TGACAAAAGA 
AAGAAGAAAG GGAGGAAGAT TCCAAAACTA GAGGATCTAC TTTCGCAGAG AGATTTCACT 
GGCGCCATTA CCCTATTGGA GTTCAAGCGC CACGTTGGGG AGCAAGAAGA CGACACTAAC 
TTATGGATTG GATACTGTGC TTTTCACCTG GGTGACTACA AGAGAGCTTT GGAGGAATAT 
GAAAATGCAA CGAAGGAGGA AAATTGCAAT CCAGAAGTGT GGGTGAACTT GGCCTGCACC 
TACTTTTTTC TTGGGATGTA TAAACAAGCA GAAGCTGCTG GGTTTAAAGC TCCAAAAAGC 
CGGCTCCAAA ACCGCCTACT GTTCCATCTG GCTCACAAGT TTAATGATGA GAAGAAATTA 
ATGAACTTTC ATCAGAATCT TCAGGATATC AAGGAAGACC AGCTTAGTTT GGCCTCAATC 
CACTACATGC GATCCCATTA CCAAGAAGCT ATTGATATAT ACAAGCGGAT CCTGCTGGAC 
AACAGGGAAT ACCTGGCCCT CAATGTGTAT GTGGCCCTCT GCTACTACAA ACTGGATTAC 
TATGATGTGT CTCAAGAAGT CCTGGCTGTT TACCTTCAGC AGATTCCTGA CAGTACCATC 
GCCCTCAACC TTAAGGCCTG CAATCACTTT CGCCTTTATA ACGGCAAAGC AGCTGAGGCA 
GAGCTCAAAA GCTTGATGGA CAATGCATCT TCACCCTTTG AATTTGCTAA AGAACTCATC 
AGGCACAATC TGGTTGTTTT CCGAGGAGGC GAAGGGGCTT TGCAGGTTTT ACCTCCCCTG 
GTTGATGTCA TTCCTGAAGC TAGGCTCAAC CTAGTGATTT ACTACCTTCG TCAAGATGAT 
GTGCAGGAAG CCTATAATTT AATCAAGGAT TTGGAACCCA CTACACCTCA GGAGTATATC 
CTCAAGGGAG TTGTCAATGC AGCCCTTGGC CAGGAAATGG GTTCAAGGGA TCATATGAAA 
ATTGCCCAGC AGTTTTTCCA GTTGGTAGGA GGATCAGCTA GTGAATGTGA TACAATACCA 
GGAAGGCAGT GCATGGCTTC CTGTTTCTTC CTACTTAAAC AATTTGATGA TGTCTTGATT 
TACCTCAACT CTTTTAAGAG TTACTTCTAT AATGATGACA TCTTTAACTT TAATTATGCC 
CAAGCCAAAG CTGCAACAGG CAATACCAGT GAGGGTGAAG AGGTTTTCCT CTTGATCCAA 
AGTGAGAAAC TGAAAAATGA CTACATTTAC CTTAGCTGGT TAGCTCGCTG CTATATTATG 
AATAAGAAAC CAAGACTAGC TTGGGAGCTT TATCTCAAGA TGGAAACCTC TGGCGAGTCC 
TTCAGCCTCT TACAGCTCAT TGCCAATGAC TGTTACAAGA TGGGCCAGTT CTACTATTCA 
GCCAAAGCTT TTGATGTCTT AGAAAGACTG GATCCCAACC CTGAGTACTG GGAAGGCAAG 
AGGGGTGCCT GTGTGGGCAT CTTCCAGATG ATCTTAGCTG GGAGAGAACC CAAAGAGACC 
CTCCGAGAAG TGCTGCATTT ACTGAGAAGC ACAGGAAACA CCCAAGTGGA GTATATCATC 
AGGATCATGA AGAAGTGGGC CAAGGAGAAT AGAGTGCCCA TCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_705828.2
CDS	68..1732
Translation	MMLSRAKPAVGGESPHTDKRKKKGRKIPKLEDLLSQRDFTGAITLLEFKRHVGEQEDDTNLWIGYCAFHLGDYKRALEEYENATKEENCNPEVWVNLACTYFFLGMYKQAEAAGFKAPKSRLQNRLLFHLAHKFNDEKKLMNFHQNLQDIKEDQLSLASIHYMRSHYQEAIDIYKRILLDNREYLALNVYVALCYYKLDYYDVSQEVLAVYLQQIPDSTIALNLKACNHFRLYNGKAAEAELKSLMDNASSPFEFAKELIRHNLVVFRGGEGALQVLPPLVDVIPEARLNLVIYYLRQDDVQEAYNLIKDLEPTTPQEYILKGVVNAALGQEMGSRDHMKIAQQFFQLVGGSASECDTIPGRQCMASCFFLLKQFDDVLIYLNSFKSYFYNDDIFNFNYAQAKAATGNTSEGEEVFLLIQSEKLKNDYIYLSWLARCYIMNKKPRLAWELYLKMETSGESFSLLQLIANDCYKMGQFYYSAKAFDVLERLDPNPEYWEGKRGACVGIFQMILAGREPKETLREVLHLLRSTGNTQVEYIIRIMKKWAKENRVPI

Target ORF information:

RefSeq Version	NM_153600.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus tetratricopeptide repeat domain 26 (Ttc26), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_153600.2

ORF Insert Sequence:

ATGATGCTTT CAAGGGCCAA ACCCGCTGTG GGCGGGGAGT CACCGCACAC TGACAAAAGA 
AAGAAGAAAG GGAGGAAGAT TCCAAAACTA GAGGATCTAC TTTCGCAGAG AGATTTCACT 
GGCGCCATTA CCCTATTGGA GTTCAAGCGC CACGTTGGGG AGCAAGAAGA CGACACTAAC 
TTATGGATTG GATACTGTGC TTTTCACCTG GGTGACTACA AGAGAGCTTT GGAGGAATAT 
GAAAATGCAA CGAAGGAGGA AAATTGCAAT CCAGAAGTGT GGGTGAACTT GGCCTGCACC 
TACTTTTTTC TTGGGATGTA TAAACAAGCA GAAGCTGCTG GGTTTAAAGC TCCAAAAAGC 
CGGCTCCAAA ACCGCCTACT GTTCCATCTG GCTCACAAGT TTAATGATGA GAAGAAATTA 
ATGAACTTTC ATCAGAATCT TCAGGATATC AAGGAAGACC AGCTTAGTTT GGCCTCAATC 
CACTACATGC GATCCCATTA CCAAGAAGCT ATTGATATAT ACAAGCGGAT CCTGCTGGAC 
AACAGGGAAT ACCTGGCCCT CAATGTGTAT GTGGCCCTCT GCTACTACAA ACTGGATTAC 
TATGATGTGT CTCAAGAAGT CCTGGCTGTT TACCTTCAGC AGATTCCTGA CAGTACCATC 
GCCCTCAACC TTAAGGCCTG CAATCACTTT CGCCTTTATA ACGGCAAAGC AGCTGAGGCA 
GAGCTCAAAA GCTTGATGGA CAATGCATCT TCACCCTTTG AATTTGCTAA AGAACTCATC 
AGGCACAATC TGGTTGTTTT CCGAGGAGGC GAAGGGGCTT TGCAGGTTTT ACCTCCCCTG 
GTTGATGTCA TTCCTGAAGC TAGGCTCAAC CTAGTGATTT ACTACCTTCG TCAAGATGAT 
GTGCAGGAAG CCTATAATTT AATCAAGGAT TTGGAACCCA CTACACCTCA GGAGTATATC 
CTCAAGGGAG TTGTCAATGC AGCCCTTGGC CAGGAAATGG GTTCAAGGGA TCATATGAAA 
ATTGCCCAGC AGTTTTTCCA GTTGGTAGGA GGATCAGCTA GTGAATGTGA TACAATACCA 
GGAAGGCAGT GCATGGCTTC CTGTTTCTTC CTACTTAAAC AATTTGATGA TGTCTTGATT 
TACCTCAACT CTTTTAAGAG TTACTTCTAT AATGATGACA TCTTTAACTT TAATTATGCC 
CAAGCCAAAG CTGCAACAGG CAATACCAGT GAGGGTGAAG AGGTTTTCCT CTTGATCCAA 
AGTGAGAAAC TGAAAAATGA CTACATTTAC CTTAGCTGGT TAGCTCGCTG CTATATTATG 
AATAAGAAAC CAAGACTAGC TTGGGAGCTT TATCTCAAGA TGGAAACCTC TGGCGAGTCC 
TTCAGCCTCT TACAGCTCAT TGCCAATGAC TGTTACAAGA TGGGCCAGTT CTACTATTCA 
GCCAAAGCTT TTGATGTCTT AGAAAGACTG GATCCCAACC CTGAGTACTG GGAAGGCAAG 
AGGGGTGCCT GTGTGGGCAT CTTCCAGATG ATCTTAGCTG GGAGAGAACC CAAAGAGACC 
CTCCGAGAAG TGCTGCATTT ACTGAGAAGC ACAGGAAACA CCCAAGTGGA GTATATCATC 
AGGATCATGA AGAAGTGGGC CAAGGAGAAT AGAGTGCCCA TCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ttc26 ( XM_006506152.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006506215.1 Mus musculus tetratricopeptide repeat domain 26 (Ttc26), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu37284
Clone ID Related Accession (Same CDS sequence)	XM_006506152.3 , XM_006506152.4
Accession Version	XM_006506152.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1557bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	intraflagellar transport protein 56 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000072.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006506152.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATGCTTT CAAGGGCCAA ACCCGCTGTG GGCGGGGAGT CACCGCACAC TGACAAAAGA 
AAGAAGAAAG GGAGGAAGAT TCCAAAACTA GAGGATCTAC TTTCGCAGAG AGATTTCACT 
GGCGCCATTA CCCTATTGGA GTTCAAGCGC CACGTTGGGG AGCAAGAAGA CGACACTAAC 
TTATGGATTG GATACTGTGC TTTTCACCTG GGTGACTACA AGAGAGCTTT GGAGGAATAT 
GAAAATGCAA CGAAGGAGGA AAATTGCAAT CCAGAAGTGT GGGTGAACTT GGCCTGCACC 
TACTTTTTTC TTGGGATGTA TAAACAAGCA GAAGCTGCTG GGTTTAAAGC TCCAAAAAGC 
CGGCTCCAAA ACCGCCTACT GTTCCATCTG GCTCACAAGT TTAATGATGA GAAGAAATTA 
ATGAACTTTC ATCAGAATCT TCAGGATATC AAGGAAGACC AGCTTAGTTT GGCCTCAATC 
CACTACATGC GATCCCATTA CCAAGAAGCT ATTGATATAT ACAAGCGGAT CCTGCTGGAC 
AACAGGGAAT ACCTGGCCCT CAATGTGTAT GTGGCCCTCT GCTACTACAA ACTGGATTAC 
TATGATGTGT CTCAAGAAGT CCTGGCTGTT TACCTTCAGC AGATTCCTGA CAGTACCATC 
GCCCTCAACC TTAAGGCCTG CAATCACTTT CGCCTTTATA ACGGCAAAGC AGCTGAGGCA 
GAGCTCAAAA GCTTGATGGA CAATGCATCT TCACCCTTTG AATTTGCTAA AGAACTCATC 
AGGCACAATC TGGTTGTTTT CCGAGGAGGC GAAGGGGCTT TGCAGGTTTT ACCTCCCCTG 
GTTGATGTCA TTCCTGAAGC TAGGCTCAAC CTAGTGATTT ACTACCTTCG TCAAGATGAT 
GTGCAGGAAG CCTATAATTT AATCAAGGAT TTGGAACCCA CTACACCTCA GGAGTATATC 
CTCAAGGGAG TTGTCAATGC AGCCCTTGGC CAGGAAATGG GTTCAAGGGA TCATATGAAA 
ATTGCCCAGC AGTTTTTCCA GTTGGTAGGA GGATCAGCTA GTGAATGTGA TACAATACCA 
GGAAGGCAGT GCATGGCTTC CTGTTTCTTC CTACTTAAAC AATTTGATGA TGTCTTGATT 
TACCTCAACT CTTTTAAGAG TTACTTCTAT AATGATGACA TCTTTAACTT TAATTATGCC 
CAAGCCAAAG CTGCAACAGG CAATACCAGT GAGGGTGAAG AGGTTTTCCT CTTGATCCAA 
AGTGAGAAAC TGAAAAATGA CTACATTTAC CTTAGCTGGT TAGCTCGCTG CTATATTATG 
AATAAGAAAC CAAGACTAGC TTGGGAGCTT TATCTCAAGA TGGAAACCTC TGGCGAGTCC 
TTCAGCCTCT TACAGCTCAT TGCCAATGAC TGTTACAAGA TGGGCCAGTT CTACTATTCA 
GCCAAAGCTT TTGATGTCTT AGAAAGACTG GATCCCAACC CTGAGTACTG GGAAGGCAAG 
AGGGGTGCCT GTGTGGGCAT CTTCCAGATG ATCTTAGCTG GGAGAGAACC CAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006506215.1
CDS	128..1684
Translation	MMLSRAKPAVGGESPHTDKRKKKGRKIPKLEDLLSQRDFTGAITLLEFKRHVGEQEDDTNLWIGYCAFHLGDYKRALEEYENATKEENCNPEVWVNLACTYFFLGMYKQAEAAGFKAPKSRLQNRLLFHLAHKFNDEKKLMNFHQNLQDIKEDQLSLASIHYMRSHYQEAIDIYKRILLDNREYLALNVYVALCYYKLDYYDVSQEVLAVYLQQIPDSTIALNLKACNHFRLYNGKAAEAELKSLMDNASSPFEFAKELIRHNLVVFRGGEGALQVLPPLVDVIPEARLNLVIYYLRQDDVQEAYNLIKDLEPTTPQEYILKGVVNAALGQEMGSRDHMKIAQQFFQLVGGSASECDTIPGRQCMASCFFLLKQFDDVLIYLNSFKSYFYNDDIFNFNYAQAKAATGNTSEGEEVFLLIQSEKLKNDYIYLSWLARCYIMNKKPRLAWELYLKMETSGESFSLLQLIANDCYKMGQFYYSAKAFDVLERLDPNPEYWEGKRGACVGIFQMILAGREPK

Target ORF information:

RefSeq Version	XM_006506152.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus tetratricopeptide repeat domain 26 (Ttc26), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006506152.4

ORF Insert Sequence:

ATGATGCTTT CAAGGGCCAA ACCCGCTGTG GGCGGGGAGT CACCGCACAC TGACAAAAGA 
AAGAAGAAAG GGAGGAAGAT TCCAAAACTA GAGGATCTAC TTTCGCAGAG AGATTTCACT 
GGCGCCATTA CCCTATTGGA GTTCAAGCGC CACGTTGGGG AGCAAGAAGA CGACACTAAC 
TTATGGATTG GATACTGTGC TTTTCACCTG GGTGACTACA AGAGAGCTTT GGAGGAATAT 
GAAAATGCAA CGAAGGAGGA AAATTGCAAT CCAGAAGTGT GGGTGAACTT GGCCTGCACC 
TACTTTTTTC TTGGGATGTA TAAACAAGCA GAAGCTGCTG GGTTTAAAGC TCCAAAAAGC 
CGGCTCCAAA ACCGCCTACT GTTCCATCTG GCTCACAAGT TTAATGATGA GAAGAAATTA 
ATGAACTTTC ATCAGAATCT TCAGGATATC AAGGAAGACC AGCTTAGTTT GGCCTCAATC 
CACTACATGC GATCCCATTA CCAAGAAGCT ATTGATATAT ACAAGCGGAT CCTGCTGGAC 
AACAGGGAAT ACCTGGCCCT CAATGTGTAT GTGGCCCTCT GCTACTACAA ACTGGATTAC 
TATGATGTGT CTCAAGAAGT CCTGGCTGTT TACCTTCAGC AGATTCCTGA CAGTACCATC 
GCCCTCAACC TTAAGGCCTG CAATCACTTT CGCCTTTATA ACGGCAAAGC AGCTGAGGCA 
GAGCTCAAAA GCTTGATGGA CAATGCATCT TCACCCTTTG AATTTGCTAA AGAACTCATC 
AGGCACAATC TGGTTGTTTT CCGAGGAGGC GAAGGGGCTT TGCAGGTTTT ACCTCCCCTG 
GTTGATGTCA TTCCTGAAGC TAGGCTCAAC CTAGTGATTT ACTACCTTCG TCAAGATGAT 
GTGCAGGAAG CCTATAATTT AATCAAGGAT TTGGAACCCA CTACACCTCA GGAGTATATC 
CTCAAGGGAG TTGTCAATGC AGCCCTTGGC CAGGAAATGG GTTCAAGGGA TCATATGAAA 
ATTGCCCAGC AGTTTTTCCA GTTGGTAGGA GGATCAGCTA GTGAATGTGA TACAATACCA 
GGAAGGCAGT GCATGGCTTC CTGTTTCTTC CTACTTAAAC AATTTGATGA TGTCTTGATT 
TACCTCAACT CTTTTAAGAG TTACTTCTAT AATGATGACA TCTTTAACTT TAATTATGCC 
CAAGCCAAAG CTGCAACAGG CAATACCAGT GAGGGTGAAG AGGTTTTCCT CTTGATCCAA 
AGTGAGAAAC TGAAAAATGA CTACATTTAC CTTAGCTGGT TAGCTCGCTG CTATATTATG 
AATAAGAAAC CAAGACTAGC TTGGGAGCTT TATCTCAAGA TGGAAACCTC TGGCGAGTCC 
TTCAGCCTCT TACAGCTCAT TGCCAATGAC TGTTACAAGA TGGGCCAGTT CTACTATTCA 
GCCAAAGCTT TTGATGTCTT AGAAAGACTG GATCCCAACC CTGAGTACTG GGAAGGCAAG 
AGGGGTGCCT GTGTGGGCAT CTTCCAGATG ATCTTAGCTG GGAGAGAACC CAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

IFT56 regulates vertebrate developmental patterning by maintaining IFTB complex integrity and ciliary microtubule architecture.
Development (Cambridge, England)144(8)1544-1553(2017 04)
Xin D,Christopher KJ,Zeng L,Kong Y,Weatherbee SD

A mutation in the mouse ttc26 gene leads to impaired hedgehog signaling.
PLoS genetics10(10)e1004689(2014 Oct)
Swiderski RE,Nakano Y,Mullins RF,Seo S,B?nfi B

TTC26/DYF13 is an intraflagellar transport protein required for transport of motility-related proteins into flagella.
eLife3e01566(2014 Jan)
Ishikawa H,Ide T,Yagi T,Jiang X,Hirono M,Sasaki H,Yanagisawa H,Wemmer KA,Stainier DY,Qin H,Kamiya R,Marshall WF

Knockdown of ttc26 disrupts ciliogenesis of the photoreceptor cells and the pronephros in zebrafish.
Molecular biology of the cell23(16)3069-78(2012 Aug)
Zhang Q,Liu Q,Austin C,Drummond I,Pierce EA

Characterization of mouse IFT complex B.
Cell motility and the cytoskeleton66(8)457-68(2009 Aug)
Follit JA,Xu F,Keady BT,Pazour GJ

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Ttc26 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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