Qrfpr cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Qrfpr
Entrez Gene ID	229214
Full Name	pyroglutamylated RFamide peptide receptor
Synonyms	AQ27,Gpr103,SP9155
General protein information	Preferred Names pyroglutamylated RFamide peptide receptor Names pyroglutamylated RFamide peptide receptor G protein-coupled receptor 103 QRFP receptor orexigenic neuropeptide QRFP receptor
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 3 Map Location: 3\|3 B

mRNA and Protein(s)

mRNA	Protein	Name
NM_198192.2	NP_937835.1	pyroglutamylated RF-amide peptide receptor

Pathways from BioSystems

Homologies

Bos taurus (cattle)	QRFPR	NP_001179610.1
Xenopus tropicalis (tropical clawed frog)	qrfpr	NP_001072295.1
Canis lupus familiaris (dog)	QRFPR	XP_540966.3
Rattus norvegicus (Norway rat)	Qrfpr	NP_937842.1
Gallus gallus (chicken)	QRFPR	NP_001120642.1
Homo sapiens (human)	QRFPR	NP_937822.2
Pan troglodytes (chimpanzee)	QRFPR	XP_001143462.1
Mus musculus (house mouse)	Qrfpr	NP_937835.1
Danio rerio (zebrafish)	LOC100149491	XP_001920042.3

Gene Ontology
Bibliography

Related articles in PubMed

Anxiolytic effect of the GPR103 receptor agonist peptide P550 (homolog of neuropeptide 26RFa) in mice. Involvement of neurotransmitters.
Palotai M, Telegdy G
Peptides8220-25(2016 Aug)

Neuropeptide Y family receptors traffic via the Bardet-Biedl syndrome pathway to signal in neuronal primary cilia.
Loktev AV, Jackson PK
Cell reports5(5)1316-29(2013 Dec)

GPR103b functions in the peripheral regulation of adipogenesis.
Mulumba M, Jossart C, Granata R, Gallo D, Escher E, Ghigo E, Servant MJ, Marleau S, Ong H
Molecular endocrinology (Baltimore, Md.)24(8)1615-25(2010 Aug)

A neuropeptide ligand of the G protein-coupled receptor GPR103 regulates feeding, behavioral arousal, and blood pressure in mice.
Takayasu S, Sakurai T, Iwasaki S, Teranishi H, Yamanaka A, Williams SC, Iguchi H, Kawasawa YI, Ikeda Y, Sakakibara I, Ohno K, Ioka RX, Murakami S, Dohmae N, Xie J, Suda T, Motoike T, Ohuchi T, Yanagisawa M, Sakai J
Proceedings of the National Academy of Sciences of the United States of America103(19)7438-43(2006 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

we treated mice with the synthetic GPR103 receptor agonist peptide P550 and the anxious behavior was investigated using an elevated plus-maze test.
Title: Anxiolytic effect of the GPR103 receptor agonist peptide P550 (homolog of neuropeptide 26RFa) in mice. Involvement of neurotransmitters.

Results suggest that GPR103b and QRFP work in an autocrine/paracrine manner to regulate adipogenesis.
Title: GPR103b functions in the peripheral regulation of adipogenesis.

QRFP and GPR103A/B may regulate diverse neuroendocrine and behavioral functions and implicate this neuropeptide system in metabolic syndrome
Title: A neuropeptide ligand of the G protein-coupled receptor GPR103 regulates feeding, behavioral arousal, and blood pressure in mice.

Osteopenia in GPR103-/- mice may be mediated directly by the loss of GPR103 expression in bone.
Title: The G-protein-coupled receptor GPR103 regulates bone formation.

characterization and tissue distribution of SP9155 (GPR103) ligand [GPR103/SP9155]
Title: Identification and characterization of a novel RF-amide peptide ligand for orphan G-protein-coupled receptor SP9155.

The following Qrfpr gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Qrfpr cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu08914	NM_198192.2 Latest version!	Mus musculus pyroglutamylated RFamide peptide receptor (Qrfpr), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$251.30 $359.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Qrfpr ( NM_198192.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_937835.1 Mus musculus pyroglutamylated RFamide peptide receptor (Qrfpr), mRNA.

Price & Availability↑

CloneID	OMu08914
Clone ID Related Accession (Same CDS sequence)	NM_198192.2
Accession Version	NM_198192.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1302bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-08
Organism	Mus musculus(house mouse)
Product	pyroglutamylated RF-amide peptide receptor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC096610.1. On Jun 12, 2005 this sequence version replaced NM_198192.1. ##Evidence-Data-START## Transcript exon combination :: BC096610.1, AK142880.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164139 [ECO:0000348] ##Evidence-Data-END##

ATGCAGGCGC TCAACATCAC CGCGGAGCAG TTTTCCCGGC TGCTGAGCGC GCACAACCTG 
ACTCGGGAAC AGTTCATTCA TCGCTATGGG CTGCGACCGC TGGTCTACAC TCCGGAGCTG 
CCCGCGCGCG CTAAACTGGC CTTTGCGCTG GCTGGAGCAC TCATTTTTGC CCTGGCGCTC 
TTTGGCAACT CTCTGGTCAT CTATGTGGTG ACCCGCAGCA AGGCCATGCG CACCGTCACC 
AACATCTTCA TCTGCTCTCT GGCACTCAGT GATCTGCTCA TTGCCTTCTT CTGCATCCCC 
GTCACGATGC TCCAGAACAT CTCCGACAAG TGGCTGGGTG GTGCCTTCAT CTGCAAGATG 
GTGCCCTTCG TCCAGTCCAC TGCTGTTGTG ACGGAAATCC TCACCATGAC TTGCATCGCT 
GTTGAGAGGC ACCAAGGACT CATCCATCCT TTTAAAATGA AGTGGCAGTA CACTACCCGA 
AGGGCTTTCA CAATCTTGGG TGTGGTCTGG TTGGCAGCCA TCATCGTAGG ATCACCCATG 
TGGCACGTAC AACGCCTCGA GATTAAGTAT GACTTCCTCT ATGAGAAAGA ACATGTCTGC 
TGTTTGGAAG AGTGGGCCAG CCCCATGCAC CAGAGAATCT ACACCACCTT CATCCTCGTC 
ATCCTCTTCC TCCTGCCGCT TGTGGTGATG CTTGTCCTCT ACAGCAAGAT TGGCTATGAA 
CTGTGGATCA AGAAGAGAGT TGGAGACAGT TCAGCACTTC AGACTATCCA CGGGAAAGAA 
ATGTCCAAAA TAGCCAGGAA GAAGAAGCGG GCTGTCGTTA TGATGGTGAC AGTGGTGGCT 
CTCTTCGCTG CGTGCTGGGC ACCTTTCCAT GTTGTTCACA TGATGGTTGA GTACAGTAAC 
TTTGAAAAAG AGTATGATGA TGTCACAATC AAGATGGTTT TTGCTGTTGC ACAAACAATT 
GGCTTTTTCA ACTCCATCTG TAATCCCTTT GTGTATGCAT TTATGAATGA AAACTTCAAA 
AAGAATTTTT TGTCTGCGGT TTGTTATTGC ATAGTAAGAG AAACCTTCTC CCCAGGACAG 
AAGCCTGGAA ATTCTGGGAT TTCAATGATG CAAAAGAGAG CAAAGTTATC ACGATCACAG 
CGTCCAGTGG CGGAAGCCAA AGGAGACTTA TTCAGCGATG CCAACGTTGA TGTCAAATTG 
TGTGAGCAGC CAGGGGAGAA AAGGCAACTC AAGCGACAGC TTGCCTTCTT TAGTTCTGAA 
CTTTCTGAAA ACTCTACTTT CGGCAGTGGA CATGAACTGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_937835.1
CDS	37..1338
Translation	MQALNITAEQFSRLLSAHNLTREQFIHRYGLRPLVYTPELPARAKLAFALAGALIFALALFGNSLVIYVVTRSKAMRTVTNIFICSLALSDLLIAFFCIPVTMLQNISDKWLGGAFICKMVPFVQSTAVVTEILTMTCIAVERHQGLIHPFKMKWQYTTRRAFTILGVVWLAAIIVGSPMWHVQRLEIKYDFLYEKEHVCCLEEWASPMHQRIYTTFILVILFLLPLVVMLVLYSKIGYELWIKKRVGDSSALQTIHGKEMSKIARKKKRAVVMMVTVVALFAACWAPFHVVHMMVEYSNFEKEYDDVTIKMVFAVAQTIGFFNSICNPFVYAFMNENFKKNFLSAVCYCIVRETFSPGQKPGNSGISMMQKRAKLSRSQRPVAEAKGDLFSDANVDVKLCEQPGEKRQLKRQLAFFSSELSENSTFGSGHEL

Target ORF information:

RefSeq Version	NM_198192.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus pyroglutamylated RFamide peptide receptor (Qrfpr), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_198192.2

ORF Insert Sequence:

ATGCAGGCGC TCAACATCAC CGCGGAGCAG TTTTCCCGGC TGCTGAGCGC GCACAACCTG 
ACTCGGGAAC AGTTCATTCA TCGCTATGGG CTGCGACCGC TGGTCTACAC TCCGGAGCTG 
CCCGCGCGCG CTAAACTGGC CTTTGCGCTG GCTGGAGCAC TCATTTTTGC CCTGGCGCTC 
TTTGGCAACT CTCTGGTCAT CTATGTGGTG ACCCGCAGCA AGGCCATGCG CACCGTCACC 
AACATCTTCA TCTGCTCTCT GGCACTCAGT GATCTGCTCA TTGCCTTCTT CTGCATCCCC 
GTCACGATGC TCCAGAACAT CTCCGACAAG TGGCTGGGTG GTGCCTTCAT CTGCAAGATG 
GTGCCCTTCG TCCAGTCCAC TGCTGTTGTG ACGGAAATCC TCACCATGAC TTGCATCGCT 
GTTGAGAGGC ACCAAGGACT CATCCATCCT TTTAAAATGA AGTGGCAGTA CACTACCCGA 
AGGGCTTTCA CAATCTTGGG TGTGGTCTGG TTGGCAGCCA TCATCGTAGG ATCACCCATG 
TGGCACGTAC AACGCCTCGA GATTAAGTAT GACTTCCTCT ATGAGAAAGA ACATGTCTGC 
TGTTTGGAAG AGTGGGCCAG CCCCATGCAC CAGAGAATCT ACACCACCTT CATCCTCGTC 
ATCCTCTTCC TCCTGCCGCT TGTGGTGATG CTTGTCCTCT ACAGCAAGAT TGGCTATGAA 
CTGTGGATCA AGAAGAGAGT TGGAGACAGT TCAGCACTTC AGACTATCCA CGGGAAAGAA 
ATGTCCAAAA TAGCCAGGAA GAAGAAGCGG GCTGTCGTTA TGATGGTGAC AGTGGTGGCT 
CTCTTCGCTG CGTGCTGGGC ACCTTTCCAT GTTGTTCACA TGATGGTTGA GTACAGTAAC 
TTTGAAAAAG AGTATGATGA TGTCACAATC AAGATGGTTT TTGCTGTTGC ACAAACAATT 
GGCTTTTTCA ACTCCATCTG TAATCCCTTT GTGTATGCAT TTATGAATGA AAACTTCAAA 
AAGAATTTTT TGTCTGCGGT TTGTTATTGC ATAGTAAGAG AAACCTTCTC CCCAGGACAG 
AAGCCTGGAA ATTCTGGGAT TTCAATGATG CAAAAGAGAG CAAAGTTATC ACGATCACAG 
CGTCCAGTGG CGGAAGCCAA AGGAGACTTA TTCAGCGATG CCAACGTTGA TGTCAAATTG 
TGTGAGCAGC CAGGGGAGAA AAGGCAACTC AAGCGACAGC TTGCCTTCTT TAGTTCTGAA 
CTTTCTGAAA ACTCTACTTT CGGCAGTGGA CATGAACTGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Anxiolytic effect of the GPR103 receptor agonist peptide P550 (homolog of neuropeptide 26RFa) in mice. Involvement of neurotransmitters.
Peptides8220-25(2016 Aug)
Palotai M,Telegdy G

Neuropeptide Y family receptors traffic via the Bardet-Biedl syndrome pathway to signal in neuronal primary cilia.
Cell reports5(5)1316-29(2013 Dec)
Loktev AV,Jackson PK

GPR103b functions in the peripheral regulation of adipogenesis.
Molecular endocrinology (Baltimore, Md.)24(8)1615-25(2010 Aug)
Mulumba M,Jossart C,Granata R,Gallo D,Escher E,Ghigo E,Servant MJ,Marleau S,Ong H

A neuropeptide ligand of the G protein-coupled receptor GPR103 regulates feeding, behavioral arousal, and blood pressure in mice.
Proceedings of the National Academy of Sciences of the United States of America103(19)7438-43(2006 May)
Takayasu S,Sakurai T,Iwasaki S,Teranishi H,Yamanaka A,Williams SC,Iguchi H,Kawasawa YI,Ikeda Y,Sakakibara I,Ohno K,Ioka RX,Murakami S,Dohmae N,Xie J,Suda T,Motoike T,Ohuchi T,Yanagisawa M,Sakai J

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Qrfpr cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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