Utp6 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Utp6
Entrez Gene ID	216987
Full Name	UTP6 small subunit processome component
Synonyms	4732497O03Rik,HCA66
General protein information	Preferred Names UTP6 small subunit processome component Names U3 small nucleolar RNA-associated protein 6 homolog UTP6, small subunit (SSU) processome component, homolog hepatocellular carcinoma-associated antigen 66 multiple hat domains protein
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 11 Map Location: 11 B5\|11 47.29 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_144826.3	NP_659075.1	U3 small nucleolar RNA-associated protein 6 homolog

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	UTP6	XP_511397.4
Danio rerio (zebrafish)	utp6	NP_001104677.1
Arabidopsis thaliana (thale cress)	AT4G28200	NP_194549.1
	UTP6	XP_001112332.1
Canis lupus familiaris (dog)	UTP6	XP_853877.1
Bos taurus (cattle)	UTP6	NP_001092610.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP008427	XP_317018.3
Oryza sativa (rice)	Os02g0103900	NP_001045609.1
Mus musculus (house mouse)	Utp6	NP_659075.1
Gallus gallus (chicken)	UTP6	NP_001006207.1
Drosophila melanogaster (fruit fly)	CG7246	NP_572520.1
Homo sapiens (human)	UTP6	NP_060898.2
Rattus norvegicus (Norway rat)	Utp6	XP_006247026.1
Xenopus tropicalis (tropical clawed frog)	utp6	NP_001016855.1

Gene Ontology
Bibliography

Related articles in PubMed

ADAP2 in heart development: a candidate gene for the occurrence of cardiovascular malformations in NF1 microdeletion syndrome.
Venturin M, Carra S, Gaudenzi G, Brunelli S, Gallo GR, Moncini S, Cotelli F, Riva P
Journal of medical genetics51(7)436-43(2014 Jul)

A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H
Developmental cell17(6)836-48(2009 Dec)

Positive regulation of apoptosis by HCA66, a new Apaf-1 interacting protein, and its putative role in the physiopathology of NF1 microdeletion syndrome patients.
Piddubnyak V, Rigou P, Michel L, Rain JC, Geneste O, Wolkenstein P, Vidaud D, Hickman JA, Mauviel A, Poyet JL
Cell death and differentiation14(6)1222-33(2007 Jun)

Evidence by expression analysis of candidate genes for congenital heart defects in the NF1 microdeletion interval.
Venturin M, Bentivegna A, Moroni R, Larizza L, Riva P
Annals of human genetics69(Pt 5)508-16(2005 Sep)

Bioinformatics and cellular signaling.
Papin J, Subramaniam S
Current opinion in biotechnology15(1)78-81(2004 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Results suggest that reduced expression of HCA66, owing to haploinsufficiency of HCA66 gene, could render NF1 microdeleted patients-derived cells less susceptible to apoptosis.
Title: Positive regulation of apoptosis by HCA66, a new Apaf-1 interacting protein, and its putative role in the physiopathology of NF1 microdeletion syndrome patients.

The following Utp6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Utp6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu15129	NM_144826.3 Latest version!	Mus musculus UTP6 small subunit processome component (Utp6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$349.30 $499.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Utp6 ( NM_144826.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_659075.1 Mus musculus UTP6 small subunit processome component (Utp6), mRNA.

Price & Availability↑

CloneID	OMu15129
Clone ID Related Accession (Same CDS sequence)	NM_144826.3
Accession Version	NM_144826.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1794bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-03
Organism	Mus musculus(house mouse)
Product	U3 small nucleolar RNA-associated protein 6 homolog
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AK029151.1. On Apr 5, 2007 this sequence version replaced NM_144826.2. ##Evidence-Data-START## Transcript exon combination :: AK029151.1, SRR1660821.122685.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164135, SAMN01164143 [ECO:0000348] ##Evidence-Data-END##

ATGGCGGAGA TAATTCAGGA ACGTATAGAA GATCGAATCC CGGAGTTGGA ACAGCTGGAG 
CGCATCGGAC TCTTCAGTCA CGCGGAGATT AAGGCTATCA TCAAGAAGGC TTCCGACCTA 
GAATACAAAA TACATCGGAG AACCCTTCTC AAGGAAGACT TTATCAACTA TGTTCAATAT 
GAAATTAATC TTTTGGAGCT GATCCAGAGA AGAAGAGCAA GAATTAAATA TTCATTTAAG 
AAGGATGAGA TTGAATATTC TATGGTACAT CGGGTCCAGG GTGTCTTTGG TCGTGCTTCA 
GCGAAGTGGA AAGATGATGT TCAGCTCTGG CTCTCCTATA TAGTTTTCTG TAAGAAATGG 
GGCACCAAAA CTCACCTTAG CAAGATATTC TCTGCCATGC TTGCCATTCA CTCAAACAAG 
CCAGCTTTGT GGATCATGGC AGCCAAATGG GAAATGGAAG ACCGCTTGTC TTCAGAAAGT 
GCCAGGCAGT TATTTCTTCG AGCTCTACGC TTTCATCCCG AGTGTCCAAA GCTCTATCAA 
GAATACTTTA GGATGGAGCT GATGCATGCT GAGAAACTGA GAAAGGAGAA GCAAGAATTT 
GAAAAAGCCG CCATGGACAT GGGGGATTTT GATCATCCTG AAGAAATCCT TAAAGGCGAG 
TTGGCACGGA TCATTTATAA AAATTCTATA AGCAAGATTA AAGGTGCAGA ATTCCATGTG 
TCACTTCTTG CTATTGCTCA GCTATTTGAT TTTGCCAAAG ATCTACAGAA GGAAATTTAT 
GATGACCTTC AAGCTCTGCA CACCGATGAC CCACTCACTT GGGATTATGT GGCGCGGCGA 
GAATTAGAGA TCGAGTCCCA ACCAGGTGAA GAACAGCCTG TGTCGAAACA AGCCAAAGCA 
GTGGAAATGG GCCGAAGGGA AGAGAGGTGC TGCGCGGTGT ATGAGGAGGC AGTGAAGGCC 
CTGCCTACAG AGGCCATGTG GAAGTGTTAC ATCACCTTTT GCTTGGAGAG GTTTTCTAAG 
AAGACCAGTA GTGTGCCCCT CAGAGGGCAG AGGCTGGAAA GAACCATGCT TGCATTCAGG 
AAGGCCCATG AACTGAAGCT GCTTTCTGAA GTCCAGTACA AGCAGTGGAT TGACTTGTTG 
CTGCGCCAGG ACCTCTTCAA AGAAGCACTG CAGGTGGCAG AGGCTGGGAC CGAATTGTTC 
AAGGACTCTG TAACAATGTG GCAGACGAAG CTCCAGGTGC TCATTGACTC AAAGAGCCCG 
GATGTAGAGA TGCGCTTTGA GGAAGCCTTT GCACACCTCA AACCCCAGGT TTGTCTGCCC 
TTGTGGATTT CTTGGGCAGA GTGGAGTGAA AGTGCTAAAA GCCAGGAGGA CACGGAAGCC 
ATCTTTAAGA AAGCTATTAT AGCTGTCACA GGTGCCAGTT CAGTAACTCT GAAGGAGAAA 
TACCTGGATT GGGCCTATCG GAGTGGAGGC TACAAAAAGG CCAGAGCAGT GTTTAAAAGT 
TTACAGGAAA GCCGTCCATT TTCGGTTGAG TTTTTCAGGA AAATGATGCA GTTTGAAAAG 
GAGCAGGAAC CCTGCAAGAT GGTAAACCTG AGGGAGTATT ACGAGAGGGC GCTGAGAGAG 
TTTGGGACTT CAGATTCTGA TCTTTGGATG GATTACATCA AGGAAGAATT GAACCATCCC 
TTCGGTAAAC CTGAGAACTG CGGACAGATC TATTGGCGAG CCATGAAAAT GTTGCAGGGA 
CAGTCAGCAG AGCTGTTTGT AGCTAAACAC GCCATGCACC AGGCTGGCCA CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_659075.1
CDS	79..1872
Translation	MAEIIQERIEDRIPELEQLERIGLFSHAEIKAIIKKASDLEYKIHRRTLLKEDFINYVQYEINLLELIQRRRARIKYSFKKDEIEYSMVHRVQGVFGRASAKWKDDVQLWLSYIVFCKKWGTKTHLSKIFSAMLAIHSNKPALWIMAAKWEMEDRLSSESARQLFLRALRFHPECPKLYQEYFRMELMHAEKLRKEKQEFEKAAMDMGDFDHPEEILKGELARIIYKNSISKIKGAEFHVSLLAIAQLFDFAKDLQKEIYDDLQALHTDDPLTWDYVARRELEIESQPGEEQPVSKQAKAVEMGRREERCCAVYEEAVKALPTEAMWKCYITFCLERFSKKTSSVPLRGQRLERTMLAFRKAHELKLLSEVQYKQWIDLLLRQDLFKEALQVAEAGTELFKDSVTMWQTKLQVLIDSKSPDVEMRFEEAFAHLKPQVCLPLWISWAEWSESAKSQEDTEAIFKKAIIAVTGASSVTLKEKYLDWAYRSGGYKKARAVFKSLQESRPFSVEFFRKMMQFEKEQEPCKMVNLREYYERALREFGTSDSDLWMDYIKEELNHPFGKPENCGQIYWRAMKMLQGQSAELFVAKHAMHQAGH

Target ORF information:

RefSeq Version	NM_144826.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus UTP6 small subunit processome component (Utp6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_144826.3

ORF Insert Sequence:

ATGGCGGAGA TAATTCAGGA ACGTATAGAA GATCGAATCC CGGAGTTGGA ACAGCTGGAG 
CGCATCGGAC TCTTCAGTCA CGCGGAGATT AAGGCTATCA TCAAGAAGGC TTCCGACCTA 
GAATACAAAA TACATCGGAG AACCCTTCTC AAGGAAGACT TTATCAACTA TGTTCAATAT 
GAAATTAATC TTTTGGAGCT GATCCAGAGA AGAAGAGCAA GAATTAAATA TTCATTTAAG 
AAGGATGAGA TTGAATATTC TATGGTACAT CGGGTCCAGG GTGTCTTTGG TCGTGCTTCA 
GCGAAGTGGA AAGATGATGT TCAGCTCTGG CTCTCCTATA TAGTTTTCTG TAAGAAATGG 
GGCACCAAAA CTCACCTTAG CAAGATATTC TCTGCCATGC TTGCCATTCA CTCAAACAAG 
CCAGCTTTGT GGATCATGGC AGCCAAATGG GAAATGGAAG ACCGCTTGTC TTCAGAAAGT 
GCCAGGCAGT TATTTCTTCG AGCTCTACGC TTTCATCCCG AGTGTCCAAA GCTCTATCAA 
GAATACTTTA GGATGGAGCT GATGCATGCT GAGAAACTGA GAAAGGAGAA GCAAGAATTT 
GAAAAAGCCG CCATGGACAT GGGGGATTTT GATCATCCTG AAGAAATCCT TAAAGGCGAG 
TTGGCACGGA TCATTTATAA AAATTCTATA AGCAAGATTA AAGGTGCAGA ATTCCATGTG 
TCACTTCTTG CTATTGCTCA GCTATTTGAT TTTGCCAAAG ATCTACAGAA GGAAATTTAT 
GATGACCTTC AAGCTCTGCA CACCGATGAC CCACTCACTT GGGATTATGT GGCGCGGCGA 
GAATTAGAGA TCGAGTCCCA ACCAGGTGAA GAACAGCCTG TGTCGAAACA AGCCAAAGCA 
GTGGAAATGG GCCGAAGGGA AGAGAGGTGC TGCGCGGTGT ATGAGGAGGC AGTGAAGGCC 
CTGCCTACAG AGGCCATGTG GAAGTGTTAC ATCACCTTTT GCTTGGAGAG GTTTTCTAAG 
AAGACCAGTA GTGTGCCCCT CAGAGGGCAG AGGCTGGAAA GAACCATGCT TGCATTCAGG 
AAGGCCCATG AACTGAAGCT GCTTTCTGAA GTCCAGTACA AGCAGTGGAT TGACTTGTTG 
CTGCGCCAGG ACCTCTTCAA AGAAGCACTG CAGGTGGCAG AGGCTGGGAC CGAATTGTTC 
AAGGACTCTG TAACAATGTG GCAGACGAAG CTCCAGGTGC TCATTGACTC AAAGAGCCCG 
GATGTAGAGA TGCGCTTTGA GGAAGCCTTT GCACACCTCA AACCCCAGGT TTGTCTGCCC 
TTGTGGATTT CTTGGGCAGA GTGGAGTGAA AGTGCTAAAA GCCAGGAGGA CACGGAAGCC 
ATCTTTAAGA AAGCTATTAT AGCTGTCACA GGTGCCAGTT CAGTAACTCT GAAGGAGAAA 
TACCTGGATT GGGCCTATCG GAGTGGAGGC TACAAAAAGG CCAGAGCAGT GTTTAAAAGT 
TTACAGGAAA GCCGTCCATT TTCGGTTGAG TTTTTCAGGA AAATGATGCA GTTTGAAAAG 
GAGCAGGAAC CCTGCAAGAT GGTAAACCTG AGGGAGTATT ACGAGAGGGC GCTGAGAGAG 
TTTGGGACTT CAGATTCTGA TCTTTGGATG GATTACATCA AGGAAGAATT GAACCATCCC 
TTCGGTAAAC CTGAGAACTG CGGACAGATC TATTGGCGAG CCATGAAAAT GTTGCAGGGA 
CAGTCAGCAG AGCTGTTTGT AGCTAAACAC GCCATGCACC AGGCTGGCCA CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

ADAP2 in heart development: a candidate gene for the occurrence of cardiovascular malformations in NF1 microdeletion syndrome.
Journal of medical genetics51(7)436-43(2014 Jul)
Venturin M,Carra S,Gaudenzi G,Brunelli S,Gallo GR,Moncini S,Cotelli F,Riva P

A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Developmental cell17(6)836-48(2009 Dec)
Yokoyama S,Ito Y,Ueno-Kudoh H,Shimizu H,Uchibe K,Albini S,Mitsuoka K,Miyaki S,Kiso M,Nagai A,Hikata T,Osada T,Fukuda N,Yamashita S,Harada D,Mezzano V,Kasai M,Puri PL,Hayashizaki Y,Okado H,Hashimoto M,Asahara H

Positive regulation of apoptosis by HCA66, a new Apaf-1 interacting protein, and its putative role in the physiopathology of NF1 microdeletion syndrome patients.
Cell death and differentiation14(6)1222-33(2007 Jun)
Piddubnyak V,Rigou P,Michel L,Rain JC,Geneste O,Wolkenstein P,Vidaud D,Hickman JA,Mauviel A,Poyet JL

Evidence by expression analysis of candidate genes for congenital heart defects in the NF1 microdeletion interval.
Annals of human genetics69(Pt 5)508-16(2005 Sep)
Venturin M,Bentivegna A,Moroni R,Larizza L,Riva P

Bioinformatics and cellular signaling.
Current opinion in biotechnology15(1)78-81(2004 Feb)
Papin J,Subramaniam S

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Utp6 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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