Nkx2-3 cDNA ORF clone, Mus musculus(house mouse)

ARID3A is required for mammalian placenta development.
Rhee C, Edwards M, Dang C, Harris J, Brown M, Kim J, Tucker HO
Developmental biology422(2)83-91(2017 02)

Homeobox NKX2-3 promotes marginal-zone lymphomagenesis by activating B-cell receptor signalling and shaping lymphocyte dynamics.
Robles EF, Mena-Varas M, Barrio L, Merino-Cortes SV, Balogh P, Du MQ, Akasaka T, Parker A, Roa S, Panizo C, Martin-Guerrero I, Siebert R, Segura V, Agirre X, Macri-Pellizeri L, Aldaz B, Vilas-Zornoza A, Zhang S, Moody S, Calasanz MJ, Tousseyn T, Broccardo C, Brousset P, Campos-Sanchez E, Cobaleda C, Sanchez-Garcia I, Fernandez-Luna JL, Garcia-Mu?oz R, Pena E, Bellosillo B, Salar A, Baptista MJ, Hernandez-Rivas JM, Gonzalez M, Terol MJ, Climent J, Ferrandez A, Sagaert X, Melnick AM, Prosper F, Oscier DG, Carrasco YR, Dyer MJ, Martinez-Climent JA
Nature communications711889(2016 Jun)

Absence of Nkx2-3 homeodomain transcription factor reprograms the endothelial addressin preference for lymphocyte homing in Peyer's patches.
Kellermayer Z, Mihalj M, L?badi ?, Cz?mp?ly T, Lee M, O'Hara E, Butcher EC, Berta G, Balogh A, Arnold HH, Balogh P
Journal of immunology (Baltimore, Md. : 1950)193(10)5284-93(2014 Nov)

Wnt/?-catenin signaling maintains the mesenchymal precursor pool for murine sinus horn formation.
Norden J, Greulich F, Rudat C, Taketo MM, Kispert A
Circulation research109(6)e42-50(2011 Sep)

Nkx2-3 deficiency reprograms the endothelial addressin preference for lymphocyte homing in Peyer's patches.
Title: Absence of Nkx2-3 homeodomain transcription factor reprograms the endothelial addressin preference for lymphocyte homing in Peyer's patches.

The splenic vascular defects in Nkx2-3 deficiency include the generation of LYVE-1(+) cysts, comprised of endothelial cells without being committed along the LEC lineage.
Title: Absence of Nkx2-3 homeodomain transcription factor induces the formation of LYVE-1-positive endothelial cysts without lymphatic commitment in the spleen.

the organ-specific patterning of splenic vasculature is critically regulated by Nkx2-3, thereby profoundly affecting the lymphocyte homing mechanism and blood filtering capacity of the spleen in a tissue-specific manner.
Title: Transcription factor Nkx2-3 controls the vascular identity and lymphocyte homing in the spleen.

Phenotypic heterogeneity among different vascular elements within distinct anatomical regions of the spleen differentially depends on developmental factors such as lymphotoxin signaling or Nkx2.3, whereas the marginal sinus is controlled by both pathways.
Title: Distinct roles of lymphotoxin-beta signaling and the homeodomain transcription factor Nkx2.3 in the ontogeny of endothelial compartments in spleen.

Formation of various white pulp fibroblast subsets is differentially affected by the presence of Nkx2.3 activity, possibly also influencing their role in various immune functions linked with complement activation and deposition.
Title: Complex organizational defects of fibroblast architecture in the mouse spleen with Nkx2.3 homeodomain deficiency.