Cxcl9 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cxcl9
Entrez Gene ID	17329
Full Name	chemokine (C-X-C motif) ligand 9
Synonyms	BB139920,CMK,Mig,MuMIG,Scyb9,crg-10
General protein information	Preferred Names chemokine (C-X-C motif) ligand 9 Names C-X-C motif chemokine 9 M119 gamma interferon-induced monokine monokine induced by gamma interferon monokine induced by interferon-gamma protein m119 small inducible cytokine B subfamily (Cys-X-Cys), member 9 small-inducible cytokine B9
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 5 Map Location: 5 E2\|5 46.51 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_008599.4	NP_032625.2	C-X-C motif chemokine 9 precursor

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Cxcl9	NP_663705.1
Mus musculus (house mouse)	Cxcl9	NP_032625.2

Gene Ontology
Bibliography

Related articles in PubMed

HPV16E7 Induced Hyperplasia Promotes CXCL9/10 Expression and Induces CXCR3
Kuo P, Tuong ZK, Teoh SM, Frazer IH, Mattarollo S, Leggatt GR
The Journal of investigative dermatology(2017 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

IFNalphaR1 signaling promoted CXCL9 and CXCL10 synthesis, suggesting that these chemokines might be involved in the LPS and CD134 costimulation response.
Title: Optimal CD4 T cell priming after LPS-based adjuvanticity with CD134 costimulation relies on CXCL9 production.

CXCL10 plays in the pathogenesis of recurrent Herpetic stromal keratitis, and that CXCL9 displays its importance when CXCL10 is absent.
Title: CXCL9 compensates for the absence of CXCL10 during recurrent Herpetic stromal keratitis.

Data suggest that the CXCL9-CXCR3 axis plays a pivotal role in the liver-specific distribution of TRAIL+ NK cells in mice.
Title: Hepatectomy leads to loss of TRAIL-expressing liver NK cells via downregulation of the CXCL9-CXCR3 axis in mice.

CXCL9 expression is strongly upregulated in PGRN KO mice and its level is correlated with severity of inflammation in a dermatitis model.
Title: Progranulin inhibits expression and release of chemokines CXCL9 and CXCL10 in a TNFR1 dependent manner.

hepatic expression of the inflammatory CXC chemokine ligands (CXCL)9 and CXCL10 strongly increased whereas homeostatic CXCL12 significantly decreased.
Title: Chemokine Transfer by Liver Sinusoidal Endothelial Cells Contributes to the Recruitment of CD4+ T Cells into the Murine Liver.

The following Cxcl9 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cxcl9 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu02312	NM_008599.4 Latest version!	Mus musculus chemokine (C-X-C motif) ligand 9 (Cxcl9), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cxcl9 ( NM_008599.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_032625.2 Mus musculus chemokine (C-X-C motif) ligand 9 (Cxcl9), mRNA.

Price & Availability↑

CloneID	OMu02312
Clone ID Related Accession (Same CDS sequence)	NM_008599.4
Accession Version	NM_008599.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 381bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Mus musculus(house mouse)
Product	C-X-C motif chemokine 9 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK042017.1 and AC122365.4. On Dec 11, 2007 this sequence version replaced NM_008599.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because transcript sequence consistent with the reference assembly was not available for all regions of the RefSeq transcript. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BY211996.1, AK156029.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN00849382 [ECO:0000348] ##Evidence-Data-END##

ATGAAGTCCG CTGTTCTTTT CCTCTTGGGC ATCATCTTCC TGGAGCAGTG TGGAGTTCGA 
GGAACCCTAG TGATAAGGAA TGCACGATGC TCCTGCATCA GCACCAGCCG AGGCACGATC 
CACTACAAAT CCCTCAAAGA CCTCAAACAG TTTGCCCCAA GCCCCAATTG CAACAAAACT 
GAAATCATTG CTACACTGAA GAACGGAGAT CAAACCTGCC TAGATCCGGA CTCGGCAAAT 
GTGAAGAAGC TGATGAAAGA ATGGGAAAAG AAGATCAGCC AAAAGAAAAA GCAAAAGAGG 
GGGAAAAAAC ATCAAAAGAA CATGAAAAAC AGAAAACCCA AAACACCCCA AAGTCGTCGT 
CGTTCAAGGA AGACTACATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_032625.2
CDS	57..437
Translation	MKSAVLFLLGIIFLEQCGVRGTLVIRNARCSCISTSRGTIHYKSLKDLKQFAPSPNCNKTEIIATLKNGDQTCLDPDSANVKKLMKEWEKKISQKKKQKRGKKHQKNMKNRKPKTPQSRRRSRKTT

Target ORF information:

RefSeq Version	NM_008599.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus chemokine (C-X-C motif) ligand 9 (Cxcl9), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_008599.4

ORF Insert Sequence:

ATGAAGTCCG CTGTTCTTTT CCTCTTGGGC ATCATCTTCC TGGAGCAGTG TGGAGTTCGA 
GGAACCCTAG TGATAAGGAA TGCACGATGC TCCTGCATCA GCACCAGCCG AGGCACGATC 
CACTACAAAT CCCTCAAAGA CCTCAAACAG TTTGCCCCAA GCCCCAATTG CAACAAAACT 
GAAATCATTG CTACACTGAA GAACGGAGAT CAAACCTGCC TAGATCCGGA CTCGGCAAAT 
GTGAAGAAGC TGATGAAAGA ATGGGAAAAG AAGATCAGCC AAAAGAAAAA GCAAAAGAGG 
GGGAAAAAAC ATCAAAAGAA CATGAAAAAC AGAAAACCCA AAACACCCCA AAGTCGTCGT 
CGTTCAAGGA AGACTACATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

HPV16E7 Induced Hyperplasia Promotes CXCL9/10 Expression and Induces CXCR3
The Journal of investigative dermatology(2017 Dec)
Kuo P,Tuong ZK,Teoh SM,Frazer IH,Mattarollo S,Leggatt GR

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Cxcl9 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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