Matr3 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Matr3
Entrez Gene ID	17184
Full Name	matrin 3
Synonyms	1110061A14Rik,2810017I02Rik,AI841759,AW555618,D030046F20Rik,mKIAA0723
General protein information	Preferred Names matrin 3 Names matrin-3
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 18 Map Location: 18 B2\|18 19.14 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_010771.6	NP_034901.2	matrin-3

Pathways from BioSystems

Homologies

Bos taurus (cattle)	MATR3	NP_001095956.1
Gallus gallus (chicken)	MATR3	NP_989478.1
Pan troglodytes (chimpanzee)	MATR3	NP_001192161.1
	MATR3	XP_001114262.1
Xenopus tropicalis (tropical clawed frog)	matr3	NP_001006792.2
Homo sapiens (human)	MATR3	NP_954659.1
Canis lupus familiaris (dog)	MATR3	NP_001192187.1
Mus musculus (house mouse)	Matr3	NP_034901.2
Rattus norvegicus (Norway rat)	Matr3	NP_062022.2

Gene Ontology
Bibliography

Related articles in PubMed

Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system.
Zhou J, Wang R, Zhang J, Zhu L, Liu W, Lu S, Chen P, Li H, Yin B, Yuan J, Qiang B, Shu P, Peng X
Biochimica et biophysica acta1860(12)1159-1168(2017 Dec)

Nuclear poly(A) binding protein 1 (PABPN1) and Matrin3 interact in muscle cells and regulate RNA processing.
Banerjee A, Vest KE, Pavlath GK, Corbett AH
Nucleic acids research45(18)10706-10725(2017 Oct)

Towards Functional Annotation of the Preimplantation Transcriptome: An RNAi Screen in Mammalian Embryos.
Cui W, Dai X, Marcho C, Han Z, Zhang K, Tremblay KD, Mager J
Scientific reports637396(2016 Nov)

Heterogeneity of Matrin 3 in the developing and aging murine central nervous system.
Rayaprolu S, D'Alton S, Crosby K, Moloney C, Howard J, Duffy C, Cabrera M, Siemienski Z, Hernandez AR, Gallego-Iradi C, Borchelt DR, Lewis J
The Journal of comparative neurology524(14)2740-52(2016 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Matrin 3 (MATR3) is a novel protein interactor of PABPN1. MATR3 together with PABPN1 is required for normal paraspeckle function.
Title: Nuclear poly(A) binding protein 1 (PABPN1) and Matrin3 interact in muscle cells and regulate RNA processing.

Matrin 3 declines significantly in the central nervous system through early development and young adulthood before stabilizing.
Title: Heterogeneity of Matrin 3 in the developing and aging murine central nervous system.

Matr3(Gt-ex13) gene trap insertion disturb the polyadenylation of MATR3 transcripts and alter Matrin 3 protein expression.
Title: MATR3 disruption in human and mouse associated with bicuspid aortic valve, aortic coarctation and patent ductus arteriosus.

homeodomain factor-localization of gene regulatory enhancer regions to a subnuclear structure, that serves as an underlying mechanism where an enhancer-bound homeodomain factor effectively activates developmental gene transcriptional programs
Title: Required enhancer-matrin-3 network interactions for a homeodomain transcription program.

Matrin 3 interacts specifically with the heat shock proteins glucose-regulated protein 78, GRP75 and glutathione S-transferase pi isoform 2.
Title: Matrin 3 co-immunoprecipitates with the heat shock proteins glucose-regulated protein 78 (GRP78), GRP75 and glutathione S-transferase ? isoform 2 (GST?2) in thymoma cells.

The following Matr3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Matr3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu14990	NM_010771.6 Latest version!	Mus musculus matrin 3 (Matr3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$496.30 $709.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Matr3 ( NM_010771.6 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_034901.2 Mus musculus matrin 3 (Matr3), mRNA.

Price & Availability↑

CloneID	OMu14990
Clone ID Related Accession (Same CDS sequence)	NM_010771.6
Accession Version	NM_010771.6 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2541bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-10
Organism	Mus musculus(house mouse)
Product	matrin-3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC121821.3. On Oct 24, 2007 this sequence version replaced NM_010771.5. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660815.232833.1, AK129199.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849380 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCCAAGT CATTCCAGCA GTCATCTCTC GGTAGGGATT CACAGGGTCA TGGGCGTGAC 
CTGTCTGCAG CAGGAATAGG CCTTCTTGCT GCTGCTACCC AGTCTTTAAG TATGCCAGCA 
TCTCTTGGAA GGATGAACCA GGGTACTGCA CGCCTTGCTA GTTTAATGAA TCTTGGAATG 
AGTTCTTCAT TGAATCAACA AGGAGCTCAT AGTGCACTGT CTTCTGCTAG TACTTCTTCC 
CATAATTTGC AGTCTATATT TAACATTGGA AGTAGAGGTC CACTCCCTTT GTCTTCTCAA 
CACCGTGGAG ATACAGACCA GGCCAGTAAT ATTTTGGCCA GCTTTGGTCT GTCTGCTAGA 
GACTTAGATG AACTGAGTCG CTATCCAGAG GACAAGATTA CTCCTGAGAA CTTGCCCCAA 
ATTCTTCTAC AGCTTAAAAG GAGGAGAACT GAAGAAGGCC CTACATTGAG TTATGGTAGA 
GATGGCAGAT CTGCTACACG GGAGCCACCA TACAGAGTAC CTAGGGATGA TTGGGAAGAA 
AAAAGGCACT TTAGAAGAGA TAGTTTTGAT GATCGTGGTC CTAGTCTCAA CCCAGTGCTT 
GATTATGACC ATGGAAGTCG TTCTCAAGAA TCTGGTTATT ATGACAGAAT GGATTATGAA 
GATGACAGAT TAAGAGATGG AGAAAGGTGT AGGGATGATT CTTTTTTTGG TGAGACCTCG 
CATAACTATC ATAAATTTGA CAGTGAGTAT GAGAGAATGG GACGTGGTCC TGGCCCCTTA 
CAAGAGAGAT CTCTCTTTGA GAAAAAGAGG GGCGCTCCTC CAAGTAGCAA TATTGAAGAC 
TTCCATGGAC TCTTACCGAA GGGTTATCCC CATCTGTGCT CTATATGTGA TTTGCCAGTT 
CATTCTAATA AGGAGTGGAG TCAACATATC AATGGAGCAA GTCACAGTCG TCGATGCCAG 
CTTCTTCTTG AAATCTACCC AGAATGGAAT CCTGACAATG ATACTGGACA CACAATGGGT 
GATCCATTCA TGCTGCAGCA GTCTACAAAC CCAGCACCAG GGATTCTGGG ACCGCCGCCT 
CCTTCATTTC ATCTTGGAGG ACCAGCAGTT GGACCAAGAG GAAATCTGGG TGCTGGTAAT 
GGAAACCTAC AAGGACCAAG ACACATGCAA AAAGGCAGAG TGGAAACCAG CCGAGTTGTT 
CACATTATGG ATTTTCAGCG AGGAAAAAAC TTGAGATACC AGCTGTTACA ACTGGTAGAA 
CCATTTGGAG TCATTTCAAA TCATCTGATT TTAAATAAAA TTAATGAGGC ATTTATTGAA 
ATGGCCACCA CAGAAGATGC TCAGGCTGCT GTGGATTATT ATACAACTAC ACCAGCATTA 
GTGTTTGGCA AGCCAGTGAG AGTTCATTTA TCCCAGAAGT ATAAGAGAAT AAAGAAACCT 
GAAGGAAAAC CAGATCAGAA GTTTGATCAA AAGCAAGAAC TTGGTCGTGT GATACATCTC 
AGCAATTTAC CTCATTCTGG CTATTCTGAC AGTGCCGTCC TCAAGCTTGC TGAGCCTTAT 
GGGAAAATAA AGAATTATAT CTTAATGAGG ATGAAAAGTC AGGCTTTTAT TGAGATGGAA 
ACCAGAGAAG ATGCAATGGC AATGGTTGAC CACTGTTTAA AGAAGGCACT TTGGTTTCAG 
GGGAGATGTG TTAAAGTTGA TCTGTCTGAG AAATACAAAA AACTGGTGCT GCGGATTCCT 
AACAGAGGCA TTGACTTACT GAAAAAAGAT AAATCCCGGA AAAGATCCTA TTCTCCAGAT 
GGAAAAGAAT CTCCAAGTGA TAAGAAGTCC AAAACTGATG CTCAGAAGAC TGAGAGTCCA 
GCTGAGGGTA AAGAACAAGA AGAGAAGTCG GGTGAGGATG GTGAGAAGGA CACCAAGGAT 
GACCAGACAG AACAGGAGCC CAGCATGCTT CTTGAATCTG AAGATGAACT GCTTGTTGAT 
GAGGAAGAAG CTGCAGCACT ACTAGAAAGT GGTAGTTCAG TGGGCGATGA GACCGATCTT 
GCTAATTTAG GGGATGTATC TTCTGATGGG AAAAAGGAGC CTTCAGATAA AGCTGTGAAA 
AAAGATCCAA GTGCTTCAGC AACATCCAAG AAAAAACTTA AAAAAGTGGA CAAGATTGAG 
GAACTTGATC AAGAAAATGA AGCTGCATTG GAAAATGGGA TTAAAAATGA GGAAAATACA 
GAACCGGGTG CCGAATCTGC TGAGAATGCT GATGATCCAA ACAAAGACAC AAGTGAAAAT 
GCAGATGGCC AAAATGATGA GAATAAGGAG GATTATACAA TTCCCGATGA GTATAGAATC 
GGACCATATC AGCCTAATGT TCCTGTTGGT ATAGACTATG TGATACCTAA AACAGGGTTT 
TACTGTAAGC TGTGTTCACT CTTTTATACA AATGAAGAAG TTGCAAAGAA TACTCATTGC 
AGCAGCCTTC CTCATTATCA GAAATTAAAG AAATTTCTGA ATAAATTGGC AGAAGAACGG 
AGGCAGAAGA AGGAAACTTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_034901.2
CDS	317..2857
Translation	MSKSFQQSSLGRDSQGHGRDLSAAGIGLLAAATQSLSMPASLGRMNQGTARLASLMNLGMSSSLNQQGAHSALSSASTSSHNLQSIFNIGSRGPLPLSSQHRGDTDQASNILASFGLSARDLDELSRYPEDKITPENLPQILLQLKRRRTEEGPTLSYGRDGRSATREPPYRVPRDDWEEKRHFRRDSFDDRGPSLNPVLDYDHGSRSQESGYYDRMDYEDDRLRDGERCRDDSFFGETSHNYHKFDSEYERMGRGPGPLQERSLFEKKRGAPPSSNIEDFHGLLPKGYPHLCSICDLPVHSNKEWSQHINGASHSRRCQLLLEIYPEWNPDNDTGHTMGDPFMLQQSTNPAPGILGPPPPSFHLGGPAVGPRGNLGAGNGNLQGPRHMQKGRVETSRVVHIMDFQRGKNLRYQLLQLVEPFGVISNHLILNKINEAFIEMATTEDAQAAVDYYTTTPALVFGKPVRVHLSQKYKRIKKPEGKPDQKFDQKQELGRVIHLSNLPHSGYSDSAVLKLAEPYGKIKNYILMRMKSQAFIEMETREDAMAMVDHCLKKALWFQGRCVKVDLSEKYKKLVLRIPNRGIDLLKKDKSRKRSYSPDGKESPSDKKSKTDAQKTESPAEGKEQEEKSGEDGEKDTKDDQTEQEPSMLLESEDELLVDEEEAAALLESGSSVGDETDLANLGDVSSDGKKEPSDKAVKKDPSASATSKKKLKKVDKIEELDQENEAALENGIKNEENTEPGAESAENADDPNKDTSENADGQNDENKEDYTIPDEYRIGPYQPNVPVGIDYVIPKTGFYCKLCSLFYTNEEVAKNTHCSSLPHYQKLKKFLNKLAEERRQKKET

Target ORF information:

RefSeq Version	NM_010771.6
Organism	Mus musculus(house mouse)
Definition	Mus musculus matrin 3 (Matr3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_010771.6

ORF Insert Sequence:

ATGTCCAAGT CATTCCAGCA GTCATCTCTC GGTAGGGATT CACAGGGTCA TGGGCGTGAC 
CTGTCTGCAG CAGGAATAGG CCTTCTTGCT GCTGCTACCC AGTCTTTAAG TATGCCAGCA 
TCTCTTGGAA GGATGAACCA GGGTACTGCA CGCCTTGCTA GTTTAATGAA TCTTGGAATG 
AGTTCTTCAT TGAATCAACA AGGAGCTCAT AGTGCACTGT CTTCTGCTAG TACTTCTTCC 
CATAATTTGC AGTCTATATT TAACATTGGA AGTAGAGGTC CACTCCCTTT GTCTTCTCAA 
CACCGTGGAG ATACAGACCA GGCCAGTAAT ATTTTGGCCA GCTTTGGTCT GTCTGCTAGA 
GACTTAGATG AACTGAGTCG CTATCCAGAG GACAAGATTA CTCCTGAGAA CTTGCCCCAA 
ATTCTTCTAC AGCTTAAAAG GAGGAGAACT GAAGAAGGCC CTACATTGAG TTATGGTAGA 
GATGGCAGAT CTGCTACACG GGAGCCACCA TACAGAGTAC CTAGGGATGA TTGGGAAGAA 
AAAAGGCACT TTAGAAGAGA TAGTTTTGAT GATCGTGGTC CTAGTCTCAA CCCAGTGCTT 
GATTATGACC ATGGAAGTCG TTCTCAAGAA TCTGGTTATT ATGACAGAAT GGATTATGAA 
GATGACAGAT TAAGAGATGG AGAAAGGTGT AGGGATGATT CTTTTTTTGG TGAGACCTCG 
CATAACTATC ATAAATTTGA CAGTGAGTAT GAGAGAATGG GACGTGGTCC TGGCCCCTTA 
CAAGAGAGAT CTCTCTTTGA GAAAAAGAGG GGCGCTCCTC CAAGTAGCAA TATTGAAGAC 
TTCCATGGAC TCTTACCGAA GGGTTATCCC CATCTGTGCT CTATATGTGA TTTGCCAGTT 
CATTCTAATA AGGAGTGGAG TCAACATATC AATGGAGCAA GTCACAGTCG TCGATGCCAG 
CTTCTTCTTG AAATCTACCC AGAATGGAAT CCTGACAATG ATACTGGACA CACAATGGGT 
GATCCATTCA TGCTGCAGCA GTCTACAAAC CCAGCACCAG GGATTCTGGG ACCGCCGCCT 
CCTTCATTTC ATCTTGGAGG ACCAGCAGTT GGACCAAGAG GAAATCTGGG TGCTGGTAAT 
GGAAACCTAC AAGGACCAAG ACACATGCAA AAAGGCAGAG TGGAAACCAG CCGAGTTGTT 
CACATTATGG ATTTTCAGCG AGGAAAAAAC TTGAGATACC AGCTGTTACA ACTGGTAGAA 
CCATTTGGAG TCATTTCAAA TCATCTGATT TTAAATAAAA TTAATGAGGC ATTTATTGAA 
ATGGCCACCA CAGAAGATGC TCAGGCTGCT GTGGATTATT ATACAACTAC ACCAGCATTA 
GTGTTTGGCA AGCCAGTGAG AGTTCATTTA TCCCAGAAGT ATAAGAGAAT AAAGAAACCT 
GAAGGAAAAC CAGATCAGAA GTTTGATCAA AAGCAAGAAC TTGGTCGTGT GATACATCTC 
AGCAATTTAC CTCATTCTGG CTATTCTGAC AGTGCCGTCC TCAAGCTTGC TGAGCCTTAT 
GGGAAAATAA AGAATTATAT CTTAATGAGG ATGAAAAGTC AGGCTTTTAT TGAGATGGAA 
ACCAGAGAAG ATGCAATGGC AATGGTTGAC CACTGTTTAA AGAAGGCACT TTGGTTTCAG 
GGGAGATGTG TTAAAGTTGA TCTGTCTGAG AAATACAAAA AACTGGTGCT GCGGATTCCT 
AACAGAGGCA TTGACTTACT GAAAAAAGAT AAATCCCGGA AAAGATCCTA TTCTCCAGAT 
GGAAAAGAAT CTCCAAGTGA TAAGAAGTCC AAAACTGATG CTCAGAAGAC TGAGAGTCCA 
GCTGAGGGTA AAGAACAAGA AGAGAAGTCG GGTGAGGATG GTGAGAAGGA CACCAAGGAT 
GACCAGACAG AACAGGAGCC CAGCATGCTT CTTGAATCTG AAGATGAACT GCTTGTTGAT 
GAGGAAGAAG CTGCAGCACT ACTAGAAAGT GGTAGTTCAG TGGGCGATGA GACCGATCTT 
GCTAATTTAG GGGATGTATC TTCTGATGGG AAAAAGGAGC CTTCAGATAA AGCTGTGAAA 
AAAGATCCAA GTGCTTCAGC AACATCCAAG AAAAAACTTA AAAAAGTGGA CAAGATTGAG 
GAACTTGATC AAGAAAATGA AGCTGCATTG GAAAATGGGA TTAAAAATGA GGAAAATACA 
GAACCGGGTG CCGAATCTGC TGAGAATGCT GATGATCCAA ACAAAGACAC AAGTGAAAAT 
GCAGATGGCC AAAATGATGA GAATAAGGAG GATTATACAA TTCCCGATGA GTATAGAATC 
GGACCATATC AGCCTAATGT TCCTGTTGGT ATAGACTATG TGATACCTAA AACAGGGTTT 
TACTGTAAGC TGTGTTCACT CTTTTATACA AATGAAGAAG TTGCAAAGAA TACTCATTGC 
AGCAGCCTTC CTCATTATCA GAAATTAAAG AAATTTCTGA ATAAATTGGC AGAAGAACGG 
AGGCAGAAGA AGGAAACTTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system.
Biochimica et biophysica acta1860(12)1159-1168(2017 Dec)
Zhou J,Wang R,Zhang J,Zhu L,Liu W,Lu S,Chen P,Li H,Yin B,Yuan J,Qiang B,Shu P,Peng X

Nuclear poly(A) binding protein 1 (PABPN1) and Matrin3 interact in muscle cells and regulate RNA processing.
Nucleic acids research45(18)10706-10725(2017 Oct)
Banerjee A,Vest KE,Pavlath GK,Corbett AH

Towards Functional Annotation of the Preimplantation Transcriptome: An RNAi Screen in Mammalian Embryos.
Scientific reports637396(2016 Nov)
Cui W,Dai X,Marcho C,Han Z,Zhang K,Tremblay KD,Mager J

Heterogeneity of Matrin 3 in the developing and aging murine central nervous system.
The Journal of comparative neurology524(14)2740-52(2016 Oct)
Rayaprolu S,D'Alton S,Crosby K,Moloney C,Howard J,Duffy C,Cabrera M,Siemienski Z,Hernandez AR,Gallego-Iradi C,Borchelt DR,Lewis J

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Matr3 cDNA ORF clone, Mus musculus(house mouse)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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