Rac3 cDNA ORF clone, Mus musculus(house mouse)

Rac3 regulates breast cancer invasion and metastasis by controlling adhesion and matrix degradation.
Donnelly SK, Cabrera R, Mao SPH, Christin JR, Wu B, Guo W, Bravo-Cordero JJ, Condeelis JS, Segall JE, Hodgson L
The Journal of cell biology216(12)4331-4349(2017 Dec)

Novel role of Rac-Mid1 signaling in medial cerebellar development.
Nakamura T, Ueyama T, Ninoyu Y, Sakaguchi H, Choijookhuu N, Hishikawa Y, Kiyonari H, Kohta M, Sakahara M, de Curtis I, Kohmura E, Hisa Y, Aiba A, Saito N
Development (Cambridge, England)144(10)1863-1875(2017 05)

Loss of Either Rac1 or Rac3 GTPase Differentially Affects the Behavior of Mutant Mice and the Development of Functional GABAergic Networks.
Pennucci R, Talpo F, Astro V, Montinaro V, Mor? L, Cursi M, Castoldi V, Chiaretti S, Bianchi V, Marenna S, Cambiaghi M, Tonoli D, Leocani L, Biella G, D'Adamo P, de Curtis I
Cerebral cortex (New York, N.Y. : 1991)26(2)873-890(2016 Feb)

Rac3 regulates breast cancer invasion and metastasis by controlling adhesion and matrix degradation.
Title: Rac3 regulates breast cancer invasion and metastasis by controlling adhesion and matrix degradation.

The results of this study show that Rac3 have a roles in the formation of GABAergic circuits, as highlighted by the differential effects of their deletion on the late maturation of specific populations.
Title: Loss of Either Rac1 or Rac3 GTPase Differentially Affects the Behavior of Mutant Mice and the Development of Functional GABAergic Networks.

This study showed that in the absence of both Rac1 and rac3, the embryonic migration of medial ganglionic eminence-derived interneurons is further impaired.
Title: Rac-GTPases Regulate Microtubule Stability and Axon Growth of Cortical GABAergic Interneurons.

This study demonistrated that Rac1 and rac3 GTPases control synergistically the development of cortical and hippocampal GABAergic interneurons in mice.
Title: Rac1 and rac3 GTPases control synergistically the development of cortical and hippocampal GABAergic interneurons.

Rac1b forms a complex with NADPH oxidase and promotes the production of reactive oxygen species, expression of Snail, and activation of the epithelial-mesenchymal transition program.
Title: Matrix compliance regulates Rac1b localization, NADPH oxidase assembly, and epithelial-mesenchymal transition.