Jund cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Jund
Entrez Gene ID	16478
Full Name	jun D proto-oncogene
Synonyms	Jund1
General protein information	Preferred Names jun D proto-oncogene Names transcription factor jun-D Jun proto-oncogene related gene d Jun proto-oncogene related gene d1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 8 Map Location: 8 B3.3\|8 34.15 cM
Summary	The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the AP1 transcription factor complex. This protein has been proposed to protect cells from p53-dependent senescence and apoptosis. Alternative translation initiation site usage results in the production of different isoforms (PMID:12105216). [provided by RefSeq, Nov 2013].

mRNA and Protein(s)

mRNA	Protein	Name
NM_010592.5	NP_034722.1	transcription factor jun-D isoform JunD-FL
NM_001286944.1	NP_001273873.1	transcription factor jun-D isoform deltaJunD

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	jund	NP_001121814.1
Mus musculus (house mouse)	Jund	NP_034722.1
Rattus norvegicus (Norway rat)	Jund	NP_620230.1
Homo sapiens (human)	JUND	NP_005345.3
Canis lupus familiaris (dog)	JUND	XP_852285.2
Bos taurus (cattle)	JUND	NP_001096723.1
Xenopus tropicalis (tropical clawed frog)	jund	XP_002937979.1

Gene Ontology
Bibliography

Related articles in PubMed

AP-1-mediated expression of brain-specific class IVa ?-tubulin in P19 embryonal carcinoma cells.
Maruyama Y, Arahara K, Kinoshita E, Arai K
The Journal of veterinary medical science76(12)1609-15(2014 Dec)

A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JLR, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A, Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR
Neuron83(2)309-323(2014 Jul)

Regulation of steatohepatitis and PPAR? signaling by distinct AP-1 dimers.
Hasenfuss SC, Bakiri L, Thomsen MK, Williams EG, Auwerx J, Wagner EF
Cell metabolism19(1)84-95(2014 Jan)

c-Jun is required for the specification of joint cell fates.
Kan A, Tabin CJ
Genes & development27(5)514-24(2013 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Differentiation-mediated activation of JunD results in enhanced TUBB4a expression in P19 embryonal carcinoma cells.
Title: AP-1-mediated expression of brain-specific class IVa ?-tubulin in P19 embryonal carcinoma cells.

JunD provides protection in aging-induced endothelial dysfunction and may represent a novel target to prevent reactive oxygen species-driven vascular aging.
Title: Deletion of the activated protein-1 transcription factor JunD induces oxidative stress and accelerates age-related endothelial dysfunction.

AP-1 composed with JunD and Fra2 protein plays a primary role in enhancing the transcription level of the CD11c gene in dendritic cells
Title: Transcriptional regulation of the mouse CD11c promoter by AP-1 complex with JunD and Fra2 in dendritic cells.

Nfe2 modulates JunD binding to the Gcm1 promoter via acetylation
Title: Nuclear factor erythroid-derived 2 (Nfe2) regulates JunD DNA-binding activity via acetylation: a novel mechanism regulating trophoblast differentiation.

5-HT2B blockade enhances liver regeneration by inhibiting induction of TGF-beta1 expression by hepatic stellate cells that is dependent on 5-HT, ERK and JunD.
Title: Stimulating healthy tissue regeneration by targeting the 5-HT?B receptor in chronic liver disease.

The following Jund gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Jund cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu00017	NM_010592.5 Latest version!	Mus musculus jun D proto-oncogene (Jund), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$188.30 $269.00
OMu14151	NM_001286944.1 Latest version!	Mus musculus jun D proto-oncogene (Jund), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$139.30 $199.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Jund ( NM_010592.5 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_034722.1 Mus musculus jun D proto-oncogene (Jund), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu00017
Clone ID Related Accession (Same CDS sequence)	NM_010592.5
Accession Version	NM_010592.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1026bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	transcription factor jun-D isoform JunD-FL
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CD354239.1, BE651959.1, BE995638.1, AI844316.1, CK621709.1, BE648283.1, BQ177858.1, AA177918.1 and BQ176138.1. On Nov 20, 2013 this sequence version replaced NM_010592.4. Transcript Variant: This variant (1) encodes two isoforms resulting from the use of alternative in-frame translation initiation codons. The longer isoform (JunD-FL) is derived from an upstream AUG (S1 ORF, PMID:12105216), while the shorter isoform (deltaJunD) is derived from a downstream AUG (S3 ORF, PMID:12105216). This RefSeq represents the longer isoform (JunD-FL). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. COMPLETENESS: complete on the 3' end.

ATGGAAACGC CCTTCTATGG CGAGGAGGCG CTGAGCGGCC TGGCTGCGGG TGCGTCGAGC 
GTCGCTGGTG CTACTGGGGC CCCCGGCGGT GGTGGCTTCG CGCCCCCGGG CCGCGCTTTC 
CCCGGGGCGC CCCCGACGAG CAGCATGCTG AAGAAAGACG CGCTGACGCT CAGCCTGGCG 
GAGCAGGGAG CGGCGGGATT GAAACCAGGG TCGGCCACTG CACCTTCTGC GCTGCGCCCC 
GACGGCGCCC CCGACGGGCT GCTGGCTTCG CCGGATCTTG GGCTGCTCAA ACTCGCGTCG 
CCGGAGCTGG AGAGGCTGAT CATCCAGTCC AACGGGCTGG TGACCACTAC CCCGACCAGT 
ACGCAGTTCC TCTACCCGAA GGTGGCAGCT AGCGAGGAGC AGGAGTTCGC CGAAGGCTTC 
GTCAAGGCGC TGGAGGACCT GCACAAGCAA AGCCAGCTGG GTGCGGCCAC CGCGGCCACC 
TCAGGGGCTC CCGCGCCTCC CGCGCCCGCC GACCTGGCCG CCACCCCCGG GGCCACGGAG 
ACCCCGGTCT ACGCCAACCT GAGCAGTTTC GCGGGTGGCG CCGGGCCCCC TGGGGGCGCG 
GCCACCGTGG CTTTCGCCGC GGAGCCAGTG CCCTTCCCGC CGCCCCCGGG CGCGCTGGGG 
CCGCCGCCAC CTCCGCATCC ACCGCGCCTG GCCGCGCTCA AGGACGAGCC GCAGACCGTG 
CCGGACGTGC CGAGCTTCGG CGACAGCCCT CCGCTGTCGC CCATCGACAT GGACACGCAA 
GAACGCATCA AGGCGGAGCG CAAGAGGCTG CGCAACCGCA TCGCCGCCTC CAAATGCCGC 
AAGCGCAAGC TGGAGCGTAT CTCGCGCCTG GAGGAGAAAG TCAAGACCCT CAAAAGCCAG 
AACACCGAGC TGGCGTCCAC CGCCAGCCTG CTGCGCGAGC AGGTGGCGCA GCTCAAACAG 
AAAGTCCTCA GCCACGTCAA CAGCGGCTGC CAGCTGCTGC CCCAGCACCA GGTCCCGGCG 
TACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_034722.1
CDS	1319..2344
Translation	METPFYGEEALSGLAAGASSVAGATGAPGGGGFAPPGRAFPGAPPTSSMLKKDALTLSLAEQGAAGLKPGSATAPSALRPDGAPDGLLASPDLGLLKLASPELERLIIQSNGLVTTTPTSTQFLYPKVAASEEQEFAEGFVKALEDLHKQSQLGAATAATSGAPAPPAPADLAATPGATETPVYANLSSFAGGAGPPGGAATVAFAAEPVPFPPPPGALGPPPPPHPPRLAALKDEPQTVPDVPSFGDSPPLSPIDMDTQERIKAERKRLRNRIAASKCRKRKLERISRLEEKVKTLKSQNTELASTASLLREQVAQLKQKVLSHVNSGCQLLPQHQVPAY

Target ORF information:

RefSeq Version	NM_010592.5
Organism	Mus musculus(house mouse)
Definition	Mus musculus jun D proto-oncogene (Jund), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_010592.5

ORF Insert Sequence:

ATGGAAACGC CCTTCTATGG CGAGGAGGCG CTGAGCGGCC TGGCTGCGGG TGCGTCGAGC 
GTCGCTGGTG CTACTGGGGC CCCCGGCGGT GGTGGCTTCG CGCCCCCGGG CCGCGCTTTC 
CCCGGGGCGC CCCCGACGAG CAGCATGCTG AAGAAAGACG CGCTGACGCT CAGCCTGGCG 
GAGCAGGGAG CGGCGGGATT GAAACCAGGG TCGGCCACTG CACCTTCTGC GCTGCGCCCC 
GACGGCGCCC CCGACGGGCT GCTGGCTTCG CCGGATCTTG GGCTGCTCAA ACTCGCGTCG 
CCGGAGCTGG AGAGGCTGAT CATCCAGTCC AACGGGCTGG TGACCACTAC CCCGACCAGT 
ACGCAGTTCC TCTACCCGAA GGTGGCAGCT AGCGAGGAGC AGGAGTTCGC CGAAGGCTTC 
GTCAAGGCGC TGGAGGACCT GCACAAGCAA AGCCAGCTGG GTGCGGCCAC CGCGGCCACC 
TCAGGGGCTC CCGCGCCTCC CGCGCCCGCC GACCTGGCCG CCACCCCCGG GGCCACGGAG 
ACCCCGGTCT ACGCCAACCT GAGCAGTTTC GCGGGTGGCG CCGGGCCCCC TGGGGGCGCG 
GCCACCGTGG CTTTCGCCGC GGAGCCAGTG CCCTTCCCGC CGCCCCCGGG CGCGCTGGGG 
CCGCCGCCAC CTCCGCATCC ACCGCGCCTG GCCGCGCTCA AGGACGAGCC GCAGACCGTG 
CCGGACGTGC CGAGCTTCGG CGACAGCCCT CCGCTGTCGC CCATCGACAT GGACACGCAA 
GAACGCATCA AGGCGGAGCG CAAGAGGCTG CGCAACCGCA TCGCCGCCTC CAAATGCCGC 
AAGCGCAAGC TGGAGCGTAT CTCGCGCCTG GAGGAGAAAG TCAAGACCCT CAAAAGCCAG 
AACACCGAGC TGGCGTCCAC CGCCAGCCTG CTGCGCGAGC AGGTGGCGCA GCTCAAACAG 
AAAGTCCTCA GCCACGTCAA CAGCGGCTGC CAGCTGCTGC CCCAGCACCA GGTCCCGGCG 
TACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Jund ( NM_001286944.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001273873.1 Mus musculus jun D proto-oncogene (Jund), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu14151
Clone ID Related Accession (Same CDS sequence)	NM_001286944.1
Accession Version	NM_001286944.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 882bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-16
Organism	Mus musculus(house mouse)
Product	transcription factor jun-D isoform deltaJunD
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CD354239.1, BE651959.1, BE995638.1, AI844316.1, CK621709.1, BE648283.1, BQ177858.1, AA177918.1 and BQ176138.1. Transcript Variant: This variant (1) encodes two isoforms resulting from the use of alternative in-frame translation initiation codons. The longer isoform (JunD-FL) is derived from an upstream AUG (S1 ORF, PMID:12105216), while the shorter isoform (deltaJunD) is derived from a downstream AUG (S3 ORF, PMID:12105216). This RefSeq represents the shorter isoform (deltaJunD). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: experimental evidence (PMID:12105216) ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCTGAAGA AAGACGCGCT GACGCTCAGC CTGGCGGAGC AGGGAGCGGC GGGATTGAAA 
CCAGGGTCGG CCACTGCACC TTCTGCGCTG CGCCCCGACG GCGCCCCCGA CGGGCTGCTG 
GCTTCGCCGG ATCTTGGGCT GCTCAAACTC GCGTCGCCGG AGCTGGAGAG GCTGATCATC 
CAGTCCAACG GGCTGGTGAC CACTACCCCG ACCAGTACGC AGTTCCTCTA CCCGAAGGTG 
GCAGCTAGCG AGGAGCAGGA GTTCGCCGAA GGCTTCGTCA AGGCGCTGGA GGACCTGCAC 
AAGCAAAGCC AGCTGGGTGC GGCCACCGCG GCCACCTCAG GGGCTCCCGC GCCTCCCGCG 
CCCGCCGACC TGGCCGCCAC CCCCGGGGCC ACGGAGACCC CGGTCTACGC CAACCTGAGC 
AGTTTCGCGG GTGGCGCCGG GCCCCCTGGG GGCGCGGCCA CCGTGGCTTT CGCCGCGGAG 
CCAGTGCCCT TCCCGCCGCC CCCGGGCGCG CTGGGGCCGC CGCCACCTCC GCATCCACCG 
CGCCTGGCCG CGCTCAAGGA CGAGCCGCAG ACCGTGCCGG ACGTGCCGAG CTTCGGCGAC 
AGCCCTCCGC TGTCGCCCAT CGACATGGAC ACGCAAGAAC GCATCAAGGC GGAGCGCAAG 
AGGCTGCGCA ACCGCATCGC CGCCTCCAAA TGCCGCAAGC GCAAGCTGGA GCGTATCTCG 
CGCCTGGAGG AGAAAGTCAA GACCCTCAAA AGCCAGAACA CCGAGCTGGC GTCCACCGCC 
AGCCTGCTGC GCGAGCAGGT GGCGCAGCTC AAACAGAAAG TCCTCAGCCA CGTCAACAGC 
GGCTGCCAGC TGCTGCCCCA GCACCAGGTC CCGGCGTACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001273873.1
CDS	1463..2344
Translation	MLKKDALTLSLAEQGAAGLKPGSATAPSALRPDGAPDGLLASPDLGLLKLASPELERLIIQSNGLVTTTPTSTQFLYPKVAASEEQEFAEGFVKALEDLHKQSQLGAATAATSGAPAPPAPADLAATPGATETPVYANLSSFAGGAGPPGGAATVAFAAEPVPFPPPPGALGPPPPPHPPRLAALKDEPQTVPDVPSFGDSPPLSPIDMDTQERIKAERKRLRNRIAASKCRKRKLERISRLEEKVKTLKSQNTELASTASLLREQVAQLKQKVLSHVNSGCQLLPQHQVPAY

Target ORF information:

RefSeq Version	NM_001286944.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus jun D proto-oncogene (Jund), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001286944.1

ORF Insert Sequence:

ATGCTGAAGA AAGACGCGCT GACGCTCAGC CTGGCGGAGC AGGGAGCGGC GGGATTGAAA 
CCAGGGTCGG CCACTGCACC TTCTGCGCTG CGCCCCGACG GCGCCCCCGA CGGGCTGCTG 
GCTTCGCCGG ATCTTGGGCT GCTCAAACTC GCGTCGCCGG AGCTGGAGAG GCTGATCATC 
CAGTCCAACG GGCTGGTGAC CACTACCCCG ACCAGTACGC AGTTCCTCTA CCCGAAGGTG 
GCAGCTAGCG AGGAGCAGGA GTTCGCCGAA GGCTTCGTCA AGGCGCTGGA GGACCTGCAC 
AAGCAAAGCC AGCTGGGTGC GGCCACCGCG GCCACCTCAG GGGCTCCCGC GCCTCCCGCG 
CCCGCCGACC TGGCCGCCAC CCCCGGGGCC ACGGAGACCC CGGTCTACGC CAACCTGAGC 
AGTTTCGCGG GTGGCGCCGG GCCCCCTGGG GGCGCGGCCA CCGTGGCTTT CGCCGCGGAG 
CCAGTGCCCT TCCCGCCGCC CCCGGGCGCG CTGGGGCCGC CGCCACCTCC GCATCCACCG 
CGCCTGGCCG CGCTCAAGGA CGAGCCGCAG ACCGTGCCGG ACGTGCCGAG CTTCGGCGAC 
AGCCCTCCGC TGTCGCCCAT CGACATGGAC ACGCAAGAAC GCATCAAGGC GGAGCGCAAG 
AGGCTGCGCA ACCGCATCGC CGCCTCCAAA TGCCGCAAGC GCAAGCTGGA GCGTATCTCG 
CGCCTGGAGG AGAAAGTCAA GACCCTCAAA AGCCAGAACA CCGAGCTGGC GTCCACCGCC 
AGCCTGCTGC GCGAGCAGGT GGCGCAGCTC AAACAGAAAG TCCTCAGCCA CGTCAACAGC 
GGCTGCCAGC TGCTGCCCCA GCACCAGGTC CCGGCGTACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

AP-1-mediated expression of brain-specific class IVa ?-tubulin in P19 embryonal carcinoma cells.
The Journal of veterinary medical science76(12)1609-15(2014 Dec)
Maruyama Y,Arahara K,Kinoshita E,Arai K

A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Neuron83(2)309-323(2014 Jul)
Thompson CL,Ng L,Menon V,Martinez S,Lee CK,Glattfelder K,Sunkin SM,Henry A,Lau C,Dang C,Garcia-Lopez R,Martinez-Ferre A,Pombero A,Rubenstein JLR,Wakeman WB,Hohmann J,Dee N,Sodt AJ,Young R,Smith K,Nguyen TN,Kidney J,Kuan L,Jeromin A,Kaykas A,Miller J,Page D,Orta G,Bernard A,Riley Z,Smith S,Wohnoutka P,Hawrylycz MJ,Puelles L,Jones AR

Regulation of steatohepatitis and PPAR? signaling by distinct AP-1 dimers.
Cell metabolism19(1)84-95(2014 Jan)
Hasenfuss SC,Bakiri L,Thomsen MK,Williams EG,Auwerx J,Wagner EF

c-Jun is required for the specification of joint cell fates.
Genes & development27(5)514-24(2013 Mar)
Kan A,Tabin CJ

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Jund cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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