Ccr10 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ccr10
Entrez Gene ID	12777
Full Name	chemokine (C-C motif) receptor 10
Synonyms	Cmkbr9,Gpr2
General protein information	Preferred Names chemokine (C-C motif) receptor 10 Names C-C chemokine receptor type 10 C-C CKR-10 CC-CKR-10 CCR-10 G protein-coupled receptor 2 chemokine C-C receptor 9
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 11 Map Location: 11 D\|11 64.34 cM

mRNA and Protein(s)

mRNA	Protein	Name
XM_011248710.1	XP_011247012.1	C-C chemokine receptor type 10 isoform X1
NM_007721.4	NP_031747.2	C-C chemokine receptor type 10

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	CCR10	XP_001162702.1
Canis lupus familiaris (dog)	CCR10	XP_849321.1
	CCR10	XP_001111554.1
Bos taurus (cattle)	CCR10	NP_001181893.1
Mus musculus (house mouse)	Ccr10	NP_031747.2
Homo sapiens (human)	CCR10	NP_057686.2
Rattus norvegicus (Norway rat)	Ccr10	NP_001102306.1
Gallus gallus (chicken)	CCR10	XP_004948677.1

Gene Ontology
Bibliography

Related articles in PubMed

Chemokine Receptor-Dependent Control of Skin Tissue-Resident Memory T Cell Formation.
Zaid A, Hor JL, Christo SN, Groom JR, Heath WR, Mackay LK, Mueller SN
Journal of immunology (Baltimore, Md. : 1950)199(7)2451-2459(2017 Oct)

Axonal domain disorganization in Caspr1 and Caspr2 mutant myelinated axons affects neuromuscular junction integrity, leading to muscle atrophy.
Saifetiarova J, Liu X, Taylor AM, Li J, Bhat MA
Journal of neuroscience research95(7)1373-1390(2017 Jul)

Losartan and Dexamethasone may inhibit chemotaxis to reduce the infiltration of Th22 cells in IgA nephropathy.
Xiao C, Zhou Q, Li X, Li H, Zhong Y, Meng T, Zhu M, Sun H, Liu S, Tang R, Pu J, Xu Y, Xiao P
International immunopharmacology42203-208(2017 Jan)

Differential developmental requirement and peripheral regulation for dermal V?4 and V?6T17 cells in health and inflammation.
Cai Y, Xue F, Fleming C, Yang J, Ding C, Ma Y, Liu M, Zhang HG, Zheng J, Xiong N, Yan J
Nature communications53986(2014 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

this study shows that losartan and dexamethasone may suppress inflammatory responses in IgA nephropathy by inhibiting CCR10 expression in Th22 cells
Title: Losartan and Dexamethasone may inhibit chemotaxis to reduce the infiltration of Th22 cells in IgA nephropathy.

controls innate and memory immune responses in the skin
Title: CCR10 regulates balanced maintenance and function of resident regulatory and effector T cells to promote immune homeostasis in the skin.

Our in vivo analysis demonstrated that uniform expression of Ccr10 on MSCs and alteration of Ccl27 level in the skin enhance extravasation of stem cells from circulation and facilitate their migration within cutaneous tissue
Title: Analysis of chemotactic molecules in bone marrow-derived mesenchymal stem cells and the skin: Ccl27-Ccr10 axis as a basis for targeting to cutaneous tissues.

These findings provide definite evidence that CCR10 is important in skin intraepithelial Vgamma3(+) T lymphocyte development
Title: CCR10 is important for the development of skin-specific gammadeltaT cells by regulating their migration and location.

CCR10 is critical for efficient localization and accumulation of immunoglobulin A antibody-secreting cells to the lactating mammary gland.
Title: An indispensable role for the chemokine receptor CCR10 in IgA antibody-secreting cell accumulation.

The following Ccr10 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ccr10 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu00679	NM_007721.4 Latest version!	Mus musculus chemokine (C-C motif) receptor 10 (Ccr10), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
OMu00679	XM_011248710.1 Latest version!	Mus musculus chemokine (C-C motif) receptor 10 (Ccr10), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ccr10 ( NM_007721.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_031747.2 Mus musculus chemokine (C-C motif) receptor 10 (Ccr10), mRNA.

Price & Availability↑

CloneID	OMu00679
Clone ID Related Accession (Same CDS sequence)	XM_011248710.1 , NM_007721.4
Accession Version	NM_007721.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1089bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-22
Organism	Mus musculus(house mouse)
Product	C-C chemokine receptor type 10
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK090044.1. On or before Sep 2, 2006 this sequence version replaced XM_894898.2, XM_905316.2, XM_983479.1, NM_007721.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK090044.1, AF215983.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGGGGACCA AGCCCACAGA GCAGGTCTCC TGGGGACTTT ACTCCGGGTA CGATGAGGAG 
GCCTATTCGG TTGGGCCGCT GCCAGAGCTC TGTTACAAGG CTGATGTCCA GGCTTTCAGT 
CGGGCCTTCC AACCCAGTGT CTCCCTGATG GTGGCTGTAC TGGGTCTGGC TGGCAATGGC 
CTAGTCTTGG CCACCCATCT GGCAGCCAGA CGAACTACCC GATCTCCCAC CTCCGTTCAC 
CTGCTCCAGT TGGCCCTGGC TGACCTTTTA TTGGCCCTGA CTTTGCCTTT TGCTGCAGCA 
GGGGCTCTTC AGGGCTGGAA TCTAGGAAGT ACCACCTGCC GTGCCATCTC AGGCCTCTAC 
TCGGCCTCTT TCCACGCTGG CTTCCTCTTC CTAGCCTGTA TCAGCGCCGA CCGCTATGTG 
GCCATCGCAC GAGCTCTCCC AGCCGGGCAG CGGCCCTCAA CGCCTAGCCG AGCGCACTTG 
GTTTCAGTCT TCGTGTGGCT GTTGTCGCTG TTTCTGGCTC TACCTGCGCT CCTTTTCAGC 
CGGGACGGGC CACGTGAAGG CCAACGACGC TGTCGGCTCA TTTTTCCCGA AAGCCTCACG 
CAGACTGTGA AAGGGGCAAG CGCAGTGGCG CAGGTGGTCC TCGGCTTCGC GCTCCCTCTG 
GGCGTCATGG CAGCCTGTTA TGCGCTCCTG GGCCGCACGC TTCTGGCCGC CAGGGGGCCA 
GAGCGGCGGC GTGCACTGCG CGTCGTGGTG GCTTTGGTGG TGGCCTTCGT GGTGCTGCAG 
TTGCCCTACA GCCTTGCCCT GCTGCTGGAT ACAGCCGATC TACTGGCAGC CCGCGAGCGG 
AGCTGCTCCT CCAGCAAGCG CAAGGATCTA GCTTTGCTGG TCACCGGCGG CTTGACCCTG 
GTCCGTTGCA GCCTCAATCC GGTGCTTTAT GCCTTTTTGG GCCTGCGTTT CCGCCGGGAC 
CTGCGGAGGC TGCTCCAGGG CGGAGGATGC AGCCCGAAGC CCAACCCTCG TGGCCGCTGC 
CCCCGTCGAC TCCGCCTTTC TTCCTGCTCT GCTCCTACTG AGACCCACAG TCTCTCTTGG 
GACAACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_031747.2
CDS	21..1109
Translation	MGTKPTEQVSWGLYSGYDEEAYSVGPLPELCYKADVQAFSRAFQPSVSLMVAVLGLAGNGLVLATHLAARRTTRSPTSVHLLQLALADLLLALTLPFAAAGALQGWNLGSTTCRAISGLYSASFHAGFLFLACISADRYVAIARALPAGQRPSTPSRAHLVSVFVWLLSLFLALPALLFSRDGPREGQRRCRLIFPESLTQTVKGASAVAQVVLGFALPLGVMAACYALLGRTLLAARGPERRRALRVVVALVVAFVVLQLPYSLALLLDTADLLAARERSCSSSKRKDLALLVTGGLTLVRCSLNPVLYAFLGLRFRRDLRRLLQGGGCSPKPNPRGRCPRRLRLSSCSAPTETHSLSWDN

Target ORF information:

RefSeq Version	NM_007721.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus chemokine (C-C motif) receptor 10 (Ccr10), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007721.4

ORF Insert Sequence:

ATGGGGACCA AGCCCACAGA GCAGGTCTCC TGGGGACTTT ACTCCGGGTA CGATGAGGAG 
GCCTATTCGG TTGGGCCGCT GCCAGAGCTC TGTTACAAGG CTGATGTCCA GGCTTTCAGT 
CGGGCCTTCC AACCCAGTGT CTCCCTGATG GTGGCTGTAC TGGGTCTGGC TGGCAATGGC 
CTAGTCTTGG CCACCCATCT GGCAGCCAGA CGAACTACCC GATCTCCCAC CTCCGTTCAC 
CTGCTCCAGT TGGCCCTGGC TGACCTTTTA TTGGCCCTGA CTTTGCCTTT TGCTGCAGCA 
GGGGCTCTTC AGGGCTGGAA TCTAGGAAGT ACCACCTGCC GTGCCATCTC AGGCCTCTAC 
TCGGCCTCTT TCCACGCTGG CTTCCTCTTC CTAGCCTGTA TCAGCGCCGA CCGCTATGTG 
GCCATCGCAC GAGCTCTCCC AGCCGGGCAG CGGCCCTCAA CGCCTAGCCG AGCGCACTTG 
GTTTCAGTCT TCGTGTGGCT GTTGTCGCTG TTTCTGGCTC TACCTGCGCT CCTTTTCAGC 
CGGGACGGGC CACGTGAAGG CCAACGACGC TGTCGGCTCA TTTTTCCCGA AAGCCTCACG 
CAGACTGTGA AAGGGGCAAG CGCAGTGGCG CAGGTGGTCC TCGGCTTCGC GCTCCCTCTG 
GGCGTCATGG CAGCCTGTTA TGCGCTCCTG GGCCGCACGC TTCTGGCCGC CAGGGGGCCA 
GAGCGGCGGC GTGCACTGCG CGTCGTGGTG GCTTTGGTGG TGGCCTTCGT GGTGCTGCAG 
TTGCCCTACA GCCTTGCCCT GCTGCTGGAT ACAGCCGATC TACTGGCAGC CCGCGAGCGG 
AGCTGCTCCT CCAGCAAGCG CAAGGATCTA GCTTTGCTGG TCACCGGCGG CTTGACCCTG 
GTCCGTTGCA GCCTCAATCC GGTGCTTTAT GCCTTTTTGG GCCTGCGTTT CCGCCGGGAC 
CTGCGGAGGC TGCTCCAGGG CGGAGGATGC AGCCCGAAGC CCAACCCTCG TGGCCGCTGC 
CCCCGTCGAC TCCGCCTTTC TTCCTGCTCT GCTCCTACTG AGACCCACAG TCTCTCTTGG 
GACAACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ccr10 ( XM_011248710.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011247012.1 Mus musculus chemokine (C-C motif) receptor 10 (Ccr10), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu00679
Clone ID Related Accession (Same CDS sequence)	XM_011248710.1 , NM_007721.4
Accession Version	XM_011248710.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1089bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-02-08
Organism	Mus musculus(House mouse)
Product	C-C chemokine receptor type 10 isoform X1
Comment

ATGGGGACCA AGCCCACAGA GCAGGTCTCC TGGGGACTTT ACTCCGGGTA CGATGAGGAG 
GCCTATTCGG TTGGGCCGCT GCCAGAGCTC TGTTACAAGG CTGATGTCCA GGCTTTCAGT 
CGGGCCTTCC AACCCAGTGT CTCCCTGATG GTGGCTGTAC TGGGTCTGGC TGGCAATGGC 
CTAGTCTTGG CCACCCATCT GGCAGCCAGA CGAACTACCC GATCTCCCAC CTCCGTTCAC 
CTGCTCCAGT TGGCCCTGGC TGACCTTTTA TTGGCCCTGA CTTTGCCTTT TGCTGCAGCA 
GGGGCTCTTC AGGGCTGGAA TCTAGGAAGT ACCACCTGCC GTGCCATCTC AGGCCTCTAC 
TCGGCCTCTT TCCACGCTGG CTTCCTCTTC CTAGCCTGTA TCAGCGCCGA CCGCTATGTG 
GCCATCGCAC GAGCTCTCCC AGCCGGGCAG CGGCCCTCAA CGCCTAGCCG AGCGCACTTG 
GTTTCAGTCT TCGTGTGGCT GTTGTCGCTG TTTCTGGCTC TACCTGCGCT CCTTTTCAGC 
CGGGACGGGC CACGTGAAGG CCAACGACGC TGTCGGCTCA TTTTTCCCGA AAGCCTCACG 
CAGACTGTGA AAGGGGCAAG CGCAGTGGCG CAGGTGGTCC TCGGCTTCGC GCTCCCTCTG 
GGCGTCATGG CAGCCTGTTA TGCGCTCCTG GGCCGCACGC TTCTGGCCGC CAGGGGGCCA 
GAGCGGCGGC GTGCACTGCG CGTCGTGGTG GCTTTGGTGG TGGCCTTCGT GGTGCTGCAG 
TTGCCCTACA GCCTTGCCCT GCTGCTGGAT ACAGCCGATC TACTGGCAGC CCGCGAGCGG 
AGCTGCTCCT CCAGCAAGCG CAAGGATCTA GCTTTGCTGG TCACCGGCGG CTTGACCCTG 
GTCCGTTGCA GCCTCAATCC GGTGCTTTAT GCCTTTTTGG GCCTGCGTTT CCGCCGGGAC 
CTGCGGAGGC TGCTCCAGGG CGGAGGATGC AGCCCGAAGC CCAACCCTCG TGGCCGCTGC 
CCCCGTCGAC TCCGCCTTTC TTCCTGCTCT GCTCCTACTG AGACCCACAG TCTCTCTTGG 
GACAACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011247012.1
Translation	MGTKPTEQVSWGLYSGYDEEAYSVGPLPELCYKADVQAFSRAFQPSVSLMVAVLGLAGNGLVLATHLAARRTTRSPTSVHLLQLALADLLLALTLPFAAAGALQGWNLGSTTCRAISGLYSASFHAGFLFLACISADRYVAIARALPAGQRPSTPSRAHLVSVFVWLLSLFLALPALLFSRDGPREGQRRCRLIFPESLTQTVKGASAVAQVVLGFALPLGVMAACYALLGRTLLAARGPERRRALRVVVALVVAFVVLQLPYSLALLLDTADLLAARERSCSSSKRKDLALLVTGGLTLVRCSLNPVLYAFLGLRFRRDLRRLLQGGGCSPKPNPRGRCPRRLRLSSCSAPTETHSLSWDN

Target ORF information:

RefSeq Version	XM_011248710.1
Organism	Mus musculus(House mouse)
Definition	Mus musculus chemokine (C-C motif) receptor 10 (Ccr10), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011248710.1

ORF Insert Sequence:

ATGGGGACCA AGCCCACAGA GCAGGTCTCC TGGGGACTTT ACTCCGGGTA CGATGAGGAG 
GCCTATTCGG TTGGGCCGCT GCCAGAGCTC TGTTACAAGG CTGATGTCCA GGCTTTCAGT 
CGGGCCTTCC AACCCAGTGT CTCCCTGATG GTGGCTGTAC TGGGTCTGGC TGGCAATGGC 
CTAGTCTTGG CCACCCATCT GGCAGCCAGA CGAACTACCC GATCTCCCAC CTCCGTTCAC 
CTGCTCCAGT TGGCCCTGGC TGACCTTTTA TTGGCCCTGA CTTTGCCTTT TGCTGCAGCA 
GGGGCTCTTC AGGGCTGGAA TCTAGGAAGT ACCACCTGCC GTGCCATCTC AGGCCTCTAC 
TCGGCCTCTT TCCACGCTGG CTTCCTCTTC CTAGCCTGTA TCAGCGCCGA CCGCTATGTG 
GCCATCGCAC GAGCTCTCCC AGCCGGGCAG CGGCCCTCAA CGCCTAGCCG AGCGCACTTG 
GTTTCAGTCT TCGTGTGGCT GTTGTCGCTG TTTCTGGCTC TACCTGCGCT CCTTTTCAGC 
CGGGACGGGC CACGTGAAGG CCAACGACGC TGTCGGCTCA TTTTTCCCGA AAGCCTCACG 
CAGACTGTGA AAGGGGCAAG CGCAGTGGCG CAGGTGGTCC TCGGCTTCGC GCTCCCTCTG 
GGCGTCATGG CAGCCTGTTA TGCGCTCCTG GGCCGCACGC TTCTGGCCGC CAGGGGGCCA 
GAGCGGCGGC GTGCACTGCG CGTCGTGGTG GCTTTGGTGG TGGCCTTCGT GGTGCTGCAG 
TTGCCCTACA GCCTTGCCCT GCTGCTGGAT ACAGCCGATC TACTGGCAGC CCGCGAGCGG 
AGCTGCTCCT CCAGCAAGCG CAAGGATCTA GCTTTGCTGG TCACCGGCGG CTTGACCCTG 
GTCCGTTGCA GCCTCAATCC GGTGCTTTAT GCCTTTTTGG GCCTGCGTTT CCGCCGGGAC 
CTGCGGAGGC TGCTCCAGGG CGGAGGATGC AGCCCGAAGC CCAACCCTCG TGGCCGCTGC 
CCCCGTCGAC TCCGCCTTTC TTCCTGCTCT GCTCCTACTG AGACCCACAG TCTCTCTTGG 
GACAACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Chemokine Receptor-Dependent Control of Skin Tissue-Resident Memory T Cell Formation.
Journal of immunology (Baltimore, Md. : 1950)199(7)2451-2459(2017 Oct)
Zaid A,Hor JL,Christo SN,Groom JR,Heath WR,Mackay LK,Mueller SN

Axonal domain disorganization in Caspr1 and Caspr2 mutant myelinated axons affects neuromuscular junction integrity, leading to muscle atrophy.
Journal of neuroscience research95(7)1373-1390(2017 Jul)
Saifetiarova J,Liu X,Taylor AM,Li J,Bhat MA

Losartan and Dexamethasone may inhibit chemotaxis to reduce the infiltration of Th22 cells in IgA nephropathy.
International immunopharmacology42203-208(2017 Jan)
Xiao C,Zhou Q,Li X,Li H,Zhong Y,Meng T,Zhu M,Sun H,Liu S,Tang R,Pu J,Xu Y,Xiao P

Differential developmental requirement and peripheral regulation for dermal V?4 and V?6T17 cells in health and inflammation.
Nature communications53986(2014 Jun)
Cai Y,Xue F,Fleming C,Yang J,Ding C,Ma Y,Liu M,Zhang HG,Zheng J,Xiong N,Yan J

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Ccr10 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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