Gene Symbol | BMPR1B |
Entrez Gene ID | 12167 |
Full Name | bone morphogenetic protein receptor, type 1B |
Synonyms | AI385617,ALK-6,AV355320,Acvrlk6,Alk6,BMPR-1B,BMPR-IB,CFK-43a,SKR6 |
General protein information |
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Gene Type | protein-coding |
Organism | Mus musculus(House mouse) |
Genome | |
Summary | This gene encodes a serine/threonine kinase that functions as a receptor for bone morphogenetic proteins (BMPs). The encoded protein is a type I receptor, and forms a complex of two type II and two type I receptors at the cell membrane. This complex signals downstream to activate SMAD transcriptional regulators. This signaling is important in skeletal and bone development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]. |