Ap3s1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ap3s1
Entrez Gene ID	11777
Full Name	adaptor-related protein complex 3, sigma 1 subunit
General protein information	Preferred Names adaptor-related protein complex 3, sigma 1 subunit Names AP-3 complex subunit sigma-1 AP-3 complex sigma-3A subunit adapter-related protein complex 3 sigma-1 subunit adaptor-related protein complex AP-3, sigma 1 subunit sigma-3A-adaptin sigma-adaptin 3a
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 18 Map Location: 18\|18 C
Summary	This gene encodes the sigma subunit of the heterotetrameric adaptor protein complex AP-3 which is involved in the formation of specialized lysosome-related compartments such as melanosomes. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. Pseudogenes of this gene are found on chromosomes 1, 8, 16, 17 and X. [provided by RefSeq, Dec 2014].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006525528.4	XP_006525591.1	AP-3 complex subunit sigma-1 isoform X2
XM_006525526.2	XP_006525589.1	AP-3 complex subunit sigma-1 isoform X1
XM_006525528.3	XP_006525591.1	AP-3 complex subunit sigma-1 isoform X2
NM_009681.5	NP_033811.1	AP-3 complex subunit sigma-1 isoform 1
NM_001303015.1	NP_001289944.1	AP-3 complex subunit sigma-1 isoform 2
XM_006525526.3	XP_006525589.1	AP-3 complex subunit sigma-1 isoform X1

Pathways from BioSystems

Homologies

	AP3S1	XP_001086177.2
Gallus gallus (chicken)	AP3S1	NP_001006586.1
Eremothecium gossypii	AGOS_AAL143W	NP_982399.1
Pan troglodytes (chimpanzee)	AP3S1	XP_001148407.1
Homo sapiens (human)	AP3S1	NP_001275.1
Mus musculus (house mouse)	Ap3s1	NP_033811.1
Rattus norvegicus (Norway rat)	Ap3s1	NP_001100403.1
Magnaporthe oryzae (rice blast fungus)	MGG_02434	XP_003709221.1
Bos taurus (cattle)	AP3S1	NP_001039881.1
Kluyveromyces lactis	KLLA0F15268g	XP_455765.1
Schizosaccharomyces pombe (fission yeast)	aps3	NP_593212.1
Canis lupus familiaris (dog)	AP3S1	XP_858735.2
Saccharomyces cerevisiae (baker's yeast)	APS3	NP_012510.3
Neurospora crassa	NCU09461	XP_963216.1

Gene Ontology
Bibliography

Related articles in PubMed

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H
Nucleic acids research42(Database issue)D802-9(2014 Jan)

The schizophrenia susceptibility factor dysbindin and its associated complex sort cargoes from cell bodies to the synapse.
Larimore J, Tornieri K, Ryder PV, Gokhale A, Zlatic SA, Craige B, Lee JD, Talbot K, Pare JF, Smith Y, Faundez V
Molecular biology of the cell22(24)4854-67(2011 Dec)

BLOC-1 interacts with BLOC-2 and the AP-3 complex to facilitate protein trafficking on endosomes.
Di Pietro SM, Falc?n-P?rez JM, Tenza D, Setty SR, Marks MS, Raposo G, Dell'Angelica EC
Molecular biology of the cell17(9)4027-38(2006 Sep)

Neural progenitor genes. Germinal zone expression and analysis of genetic overlap in stem cell populations.
Easterday MC, Dougherty JD, Jackson RL, Ou J, Nakano I, Paucar AA, Roobini B, Dianati M, Irvin DK, Weissman IL, Terskikh AV, Geschwind DH, Kornblum HI
Developmental biology264(2)309-22(2003 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Ap3s1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ap3s1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu54315	NM_001303015.1 Latest version!	Mus musculus adaptor-related protein complex 3, sigma 1 subunit (Ap3s1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OMu04652	NM_009681.5 Latest version!	Mus musculus adaptor-related protein complex 3, sigma 1 subunit (Ap3s1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu54315	XM_006525526.3 Latest version!	Mus musculus adaptor-related protein complex 3, sigma 1 subunit (Ap3s1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OMu54316	XM_006525528.4 Latest version!	Mus musculus adaptor-related protein complex 3, sigma 1 subunit (Ap3s1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OMu54316	XM_006525528.3	Mus musculus adaptor-related protein complex 3, sigma 1 subunit (Ap3s1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OMu54315	XM_006525526.2	Mus musculus adaptor-related protein complex 3, sigma 1 subunit (Ap3s1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ap3s1 ( NM_001303015.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001289944.1 Mus musculus adaptor-related protein complex 3, sigma 1 subunit (Ap3s1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu54315
Clone ID Related Accession (Same CDS sequence)	XM_006525526.2 , NM_001303015.1 , XM_006525526.3
Accession Version	NM_001303015.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 489bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	AP-3 complex subunit sigma-1 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC123927.3, BC145234.1 and AK137489.1. On Dec 12, 2014 this sequence version replaced XM_006525527.1. Transcript Variant: This variant (2) contains an additional exon, which results in a frameshift, compared to variant 1. The resulting protein (isoform 2) has a distinct C-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660813.443540.1, SRR1660813.341294.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164132 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGATCAAGG CCATCCTCAT CTTCAACAAC CACGGGAAGC CGCGGCTCTC CAAGTTCTAC 
CAGCCCTATA GTGAAGACAC GCAACAGCAA ATCATCAGGG AGACTTTCCA TTTGGTGTCT 
AAGCGCGATG AGAACGTTTG TAATTTCCTA GAAGGAGGAT TATTAATTGG AGGCTCTGAC 
AACAAGCTCA TTTACAGACA TTATGCAACA CTATATTTTG TCTTCTGTGT GGACTCCTCA 
GAAAGTGAAC TTGGCATTTT AGATCTAATT CAAGTATTTG TGGAAACATT AGACAAATGT 
TTTGAAAATG TTTGTGAACT GGATTTAATA TTCCATGTAG ACAAGGTTCA TAATATTCTT 
GCAGAAATGG TGATGGGGGG AATGGTATTG GAGACCAACA TGAATGAGAT TGTCACACAA 
ATTGATGCAC AAAATAAACT GGAGAAATCT GAGACCTTTA TCTTTCAGTC TCCCAGACAG 
GACAGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001289944.1
CDS	138..626
Translation	MIKAILIFNNHGKPRLSKFYQPYSEDTQQQIIRETFHLVSKRDENVCNFLEGGLLIGGSDNKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHVDKVHNILAEMVMGGMVLETNMNEIVTQIDAQNKLEKSETFIFQSPRQDR

Target ORF information:

RefSeq Version	NM_001303015.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus adaptor-related protein complex 3, sigma 1 subunit (Ap3s1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001303015.1

ORF Insert Sequence:

ATGATCAAGG CCATCCTCAT CTTCAACAAC CACGGGAAGC CGCGGCTCTC CAAGTTCTAC 
CAGCCCTATA GTGAAGACAC GCAACAGCAA ATCATCAGGG AGACTTTCCA TTTGGTGTCT 
AAGCGCGATG AGAACGTTTG TAATTTCCTA GAAGGAGGAT TATTAATTGG AGGCTCTGAC 
AACAAGCTCA TTTACAGACA TTATGCAACA CTATATTTTG TCTTCTGTGT GGACTCCTCA 
GAAAGTGAAC TTGGCATTTT AGATCTAATT CAAGTATTTG TGGAAACATT AGACAAATGT 
TTTGAAAATG TTTGTGAACT GGATTTAATA TTCCATGTAG ACAAGGTTCA TAATATTCTT 
GCAGAAATGG TGATGGGGGG AATGGTATTG GAGACCAACA TGAATGAGAT TGTCACACAA 
ATTGATGCAC AAAATAAACT GGAGAAATCT GAGACCTTTA TCTTTCAGTC TCCCAGACAG 
GACAGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ap3s1 ( XM_006525526.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006525589.1 Mus musculus adaptor-related protein complex 3, sigma 1 subunit (Ap3s1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu54315
Clone ID Related Accession (Same CDS sequence)	XM_006525526.2 , NM_001303015.1 , XM_006525526.3
Accession Version	XM_006525526.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 489bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	AP-3 complex subunit sigma-1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000084.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006525526.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATCAAGG CCATCCTCAT CTTCAACAAC CACGGGAAGC CGCGGCTCTC CAAGTTCTAC 
CAGCCCTATA GTGAAGACAC GCAACAGCAA ATCATCAGGG AGACTTTCCA TTTGGTGTCT 
AAGCGCGATG AGAACGTTTG TAATTTCCTA GAAGGAGGAT TATTAATTGG AGGCTCTGAC 
AACAAGCTCA TTTACAGACA TTATGCAACA CTATATTTTG TCTTCTGTGT GGACTCCTCA 
GAAAGTGAAC TTGGCATTTT AGATCTAATT CAAGTATTTG TGGAAACATT AGACAAATGT 
TTTGAAAATG TTTGTGAACT GGATTTAATA TTCCATGTAG ACAAGGTTCA TAATATTCTT 
GCAGAAATGG TGATGGGGGG AATGGTATTG GAGACCAACA TGAATGAGAT TGTCACACAA 
ATTGATGCAC AAAATAAACT GGAGAAATCT GAGACCTTTA TCTTTCAGTC TCCCAGACAG 
GACAGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006525589.1
CDS	133..621
Translation	MIKAILIFNNHGKPRLSKFYQPYSEDTQQQIIRETFHLVSKRDENVCNFLEGGLLIGGSDNKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHVDKVHNILAEMVMGGMVLETNMNEIVTQIDAQNKLEKSETFIFQSPRQDR

Target ORF information:

RefSeq Version	XM_006525526.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus adaptor-related protein complex 3, sigma 1 subunit (Ap3s1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006525526.2

ORF Insert Sequence:

ATGATCAAGG CCATCCTCAT CTTCAACAAC CACGGGAAGC CGCGGCTCTC CAAGTTCTAC 
CAGCCCTATA GTGAAGACAC GCAACAGCAA ATCATCAGGG AGACTTTCCA TTTGGTGTCT 
AAGCGCGATG AGAACGTTTG TAATTTCCTA GAAGGAGGAT TATTAATTGG AGGCTCTGAC 
AACAAGCTCA TTTACAGACA TTATGCAACA CTATATTTTG TCTTCTGTGT GGACTCCTCA 
GAAAGTGAAC TTGGCATTTT AGATCTAATT CAAGTATTTG TGGAAACATT AGACAAATGT 
TTTGAAAATG TTTGTGAACT GGATTTAATA TTCCATGTAG ACAAGGTTCA TAATATTCTT 
GCAGAAATGG TGATGGGGGG AATGGTATTG GAGACCAACA TGAATGAGAT TGTCACACAA 
ATTGATGCAC AAAATAAACT GGAGAAATCT GAGACCTTTA TCTTTCAGTC TCCCAGACAG 
GACAGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ap3s1 ( XM_006525528.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006525591.1 Mus musculus adaptor-related protein complex 3, sigma 1 subunit (Ap3s1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu54316
Clone ID Related Accession (Same CDS sequence)	XM_006525528.4 , XM_006525528.3
Accession Version	XM_006525528.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 378bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	AP-3 complex subunit sigma-1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000084.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006525528.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATCAAGG CCATCCTCAT CTTCAACAAC CACGGGAAGC CGCGGCTCTC CAAGTTCTAC 
CAGCCCTATG TATTTGTGGA AACATTAGAC AAATGTTTTG AAAATGTTTG TGAACTGGAT 
TTAATATTCC ATGTAGACAA GGTTCATAAT ATTCTTGCAG AAATGGTGAT GGGGGGAATG 
GTATTGGAGA CCAACATGAA TGAGATTGTC ACACAAATTG ATGCACAAAA TAAACTGGAG 
AAATCTGAGG CTGGCTTAGC AGGAGCTCCA GCCCGTGCTG TATCAGCTGT AAAGAATATG 
AATCTTCCTG AGATCCCAAG AAATATTAAC ATTGGTGACA TCAGTATAAA AGTGCCAAAC 
CTGCCCTCTT TTAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006525591.1
CDS	124..501
Translation	MIKAILIFNNHGKPRLSKFYQPYVFVETLDKCFENVCELDLIFHVDKVHNILAEMVMGGMVLETNMNEIVTQIDAQNKLEKSEAGLAGAPARAVSAVKNMNLPEIPRNINIGDISIKVPNLPSFK

Target ORF information:

RefSeq Version	XM_006525528.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus adaptor-related protein complex 3, sigma 1 subunit (Ap3s1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006525528.3

ORF Insert Sequence:

ATGATCAAGG CCATCCTCAT CTTCAACAAC CACGGGAAGC CGCGGCTCTC CAAGTTCTAC 
CAGCCCTATG TATTTGTGGA AACATTAGAC AAATGTTTTG AAAATGTTTG TGAACTGGAT 
TTAATATTCC ATGTAGACAA GGTTCATAAT ATTCTTGCAG AAATGGTGAT GGGGGGAATG 
GTATTGGAGA CCAACATGAA TGAGATTGTC ACACAAATTG ATGCACAAAA TAAACTGGAG 
AAATCTGAGG CTGGCTTAGC AGGAGCTCCA GCCCGTGCTG TATCAGCTGT AAAGAATATG 
AATCTTCCTG AGATCCCAAG AAATATTAAC ATTGGTGACA TCAGTATAAA AGTGCCAAAC 
CTGCCCTCTT TTAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ap3s1 ( NM_009681.5 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_033811.1 Mus musculus adaptor-related protein complex 3, sigma 1 subunit (Ap3s1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu04652
Clone ID Related Accession (Same CDS sequence)	NM_009681.5
Accession Version	NM_009681.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 582bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	AP-3 complex subunit sigma-1 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC123927.3, AK152100.1 and AK137489.1. On Dec 12, 2014 this sequence version replaced NM_009681.4. Transcript Variant: This variant (1) represents the shorter transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK137489.1, BC108327.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGATCAAGG CCATCCTCAT CTTCAACAAC CACGGGAAGC CGCGGCTCTC CAAGTTCTAC 
CAGCCCTATA GTGAAGACAC GCAACAGCAA ATCATCAGGG AGACTTTCCA TTTGGTGTCT 
AAGCGCGATG AGAACGTTTG TAATTTCCTA GAAGGAGGAT TATTAATTGG AGGCTCTGAC 
AACAAGCTCA TTTACAGACA TTATGCAACA CTATATTTTG TCTTCTGTGT GGACTCCTCA 
GAAAGTGAAC TTGGCATTTT AGATCTAATT CAAGTATTTG TGGAAACATT AGACAAATGT 
TTTGAAAATG TTTGTGAACT GGATTTAATA TTCCATGTAG ACAAGGTTCA TAATATTCTT 
GCAGAAATGG TGATGGGGGG AATGGTATTG GAGACCAACA TGAATGAGAT TGTCACACAA 
ATTGATGCAC AAAATAAACT GGAGAAATCT GAGGCTGGCT TAGCAGGAGC TCCAGCCCGT 
GCTGTATCAG CTGTAAAGAA TATGAATCTT CCTGAGATCC CAAGAAATAT TAACATTGGT 
GACATCAGTA TAAAAGTGCC AAACCTGCCC TCTTTTAAAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_033811.1
CDS	138..719
Translation	MIKAILIFNNHGKPRLSKFYQPYSEDTQQQIIRETFHLVSKRDENVCNFLEGGLLIGGSDNKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHVDKVHNILAEMVMGGMVLETNMNEIVTQIDAQNKLEKSEAGLAGAPARAVSAVKNMNLPEIPRNINIGDISIKVPNLPSFK

Target ORF information:

RefSeq Version	NM_009681.5
Organism	Mus musculus(house mouse)
Definition	Mus musculus adaptor-related protein complex 3, sigma 1 subunit (Ap3s1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_009681.5

ORF Insert Sequence:

ATGATCAAGG CCATCCTCAT CTTCAACAAC CACGGGAAGC CGCGGCTCTC CAAGTTCTAC 
CAGCCCTATA GTGAAGACAC GCAACAGCAA ATCATCAGGG AGACTTTCCA TTTGGTGTCT 
AAGCGCGATG AGAACGTTTG TAATTTCCTA GAAGGAGGAT TATTAATTGG AGGCTCTGAC 
AACAAGCTCA TTTACAGACA TTATGCAACA CTATATTTTG TCTTCTGTGT GGACTCCTCA 
GAAAGTGAAC TTGGCATTTT AGATCTAATT CAAGTATTTG TGGAAACATT AGACAAATGT 
TTTGAAAATG TTTGTGAACT GGATTTAATA TTCCATGTAG ACAAGGTTCA TAATATTCTT 
GCAGAAATGG TGATGGGGGG AATGGTATTG GAGACCAACA TGAATGAGAT TGTCACACAA 
ATTGATGCAC AAAATAAACT GGAGAAATCT GAGGCTGGCT TAGCAGGAGC TCCAGCCCGT 
GCTGTATCAG CTGTAAAGAA TATGAATCTT CCTGAGATCC CAAGAAATAT TAACATTGGT 
GACATCAGTA TAAAAGTGCC AAACCTGCCC TCTTTTAAAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ap3s1 ( XM_006525526.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006525589.1 Mus musculus adaptor-related protein complex 3, sigma 1 subunit (Ap3s1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu54315
Clone ID Related Accession (Same CDS sequence)	XM_006525526.2 , NM_001303015.1 , XM_006525526.3
Accession Version	XM_006525526.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 489bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	AP-3 complex subunit sigma-1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000084.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006525526.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATCAAGG CCATCCTCAT CTTCAACAAC CACGGGAAGC CGCGGCTCTC CAAGTTCTAC 
CAGCCCTATA GTGAAGACAC GCAACAGCAA ATCATCAGGG AGACTTTCCA TTTGGTGTCT 
AAGCGCGATG AGAACGTTTG TAATTTCCTA GAAGGAGGAT TATTAATTGG AGGCTCTGAC 
AACAAGCTCA TTTACAGACA TTATGCAACA CTATATTTTG TCTTCTGTGT GGACTCCTCA 
GAAAGTGAAC TTGGCATTTT AGATCTAATT CAAGTATTTG TGGAAACATT AGACAAATGT 
TTTGAAAATG TTTGTGAACT GGATTTAATA TTCCATGTAG ACAAGGTTCA TAATATTCTT 
GCAGAAATGG TGATGGGGGG AATGGTATTG GAGACCAACA TGAATGAGAT TGTCACACAA 
ATTGATGCAC AAAATAAACT GGAGAAATCT GAGACCTTTA TCTTTCAGTC TCCCAGACAG 
GACAGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006525589.1
CDS	320..808
Translation	MIKAILIFNNHGKPRLSKFYQPYSEDTQQQIIRETFHLVSKRDENVCNFLEGGLLIGGSDNKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHVDKVHNILAEMVMGGMVLETNMNEIVTQIDAQNKLEKSETFIFQSPRQDR

Target ORF information:

RefSeq Version	XM_006525526.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus adaptor-related protein complex 3, sigma 1 subunit (Ap3s1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006525526.3

ORF Insert Sequence:

ATGATCAAGG CCATCCTCAT CTTCAACAAC CACGGGAAGC CGCGGCTCTC CAAGTTCTAC 
CAGCCCTATA GTGAAGACAC GCAACAGCAA ATCATCAGGG AGACTTTCCA TTTGGTGTCT 
AAGCGCGATG AGAACGTTTG TAATTTCCTA GAAGGAGGAT TATTAATTGG AGGCTCTGAC 
AACAAGCTCA TTTACAGACA TTATGCAACA CTATATTTTG TCTTCTGTGT GGACTCCTCA 
GAAAGTGAAC TTGGCATTTT AGATCTAATT CAAGTATTTG TGGAAACATT AGACAAATGT 
TTTGAAAATG TTTGTGAACT GGATTTAATA TTCCATGTAG ACAAGGTTCA TAATATTCTT 
GCAGAAATGG TGATGGGGGG AATGGTATTG GAGACCAACA TGAATGAGAT TGTCACACAA 
ATTGATGCAC AAAATAAACT GGAGAAATCT GAGACCTTTA TCTTTCAGTC TCCCAGACAG 
GACAGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ap3s1 ( XM_006525528.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006525591.1 Mus musculus adaptor-related protein complex 3, sigma 1 subunit (Ap3s1), transcript variant X2, mRNA.

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CloneID	OMu54316
Clone ID Related Accession (Same CDS sequence)	XM_006525528.4 , XM_006525528.3
Accession Version	XM_006525528.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 378bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	AP-3 complex subunit sigma-1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000084.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006525528.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATCAAGG CCATCCTCAT CTTCAACAAC CACGGGAAGC CGCGGCTCTC CAAGTTCTAC 
CAGCCCTATG TATTTGTGGA AACATTAGAC AAATGTTTTG AAAATGTTTG TGAACTGGAT 
TTAATATTCC ATGTAGACAA GGTTCATAAT ATTCTTGCAG AAATGGTGAT GGGGGGAATG 
GTATTGGAGA CCAACATGAA TGAGATTGTC ACACAAATTG ATGCACAAAA TAAACTGGAG 
AAATCTGAGG CTGGCTTAGC AGGAGCTCCA GCCCGTGCTG TATCAGCTGT AAAGAATATG 
AATCTTCCTG AGATCCCAAG AAATATTAAC ATTGGTGACA TCAGTATAAA AGTGCCAAAC 
CTGCCCTCTT TTAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006525591.1
CDS	164..541
Translation	MIKAILIFNNHGKPRLSKFYQPYVFVETLDKCFENVCELDLIFHVDKVHNILAEMVMGGMVLETNMNEIVTQIDAQNKLEKSEAGLAGAPARAVSAVKNMNLPEIPRNINIGDISIKVPNLPSFK

Target ORF information:

RefSeq Version	XM_006525528.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus adaptor-related protein complex 3, sigma 1 subunit (Ap3s1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006525528.4

ORF Insert Sequence:

ATGATCAAGG CCATCCTCAT CTTCAACAAC CACGGGAAGC CGCGGCTCTC CAAGTTCTAC 
CAGCCCTATG TATTTGTGGA AACATTAGAC AAATGTTTTG AAAATGTTTG TGAACTGGAT 
TTAATATTCC ATGTAGACAA GGTTCATAAT ATTCTTGCAG AAATGGTGAT GGGGGGAATG 
GTATTGGAGA CCAACATGAA TGAGATTGTC ACACAAATTG ATGCACAAAA TAAACTGGAG 
AAATCTGAGG CTGGCTTAGC AGGAGCTCCA GCCCGTGCTG TATCAGCTGT AAAGAATATG 
AATCTTCCTG AGATCCCAAG AAATATTAAC ATTGGTGACA TCAGTATAAA AGTGCCAAAC 
CTGCCCTCTT TTAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Nucleic acids research42(Database issue)D802-9(2014 Jan)
Koscielny G,Yaikhom G,Iyer V,Meehan TF,Morgan H,Atienza-Herrero J,Blake A,Chen CK,Easty R,Di Fenza A,Fiegel T,Grifiths M,Horne A,Karp NA,Kurbatova N,Mason JC,Matthews P,Oakley DJ,Qazi A,Regnart J,Retha A,Santos LA,Sneddon DJ,Warren J,Westerberg H,Wilson RJ,Melvin DG,Smedley D,Brown SD,Flicek P,Skarnes WC,Mallon AM,Parkinson H

The schizophrenia susceptibility factor dysbindin and its associated complex sort cargoes from cell bodies to the synapse.
Molecular biology of the cell22(24)4854-67(2011 Dec)
Larimore J,Tornieri K,Ryder PV,Gokhale A,Zlatic SA,Craige B,Lee JD,Talbot K,Pare JF,Smith Y,Faundez V

BLOC-1 interacts with BLOC-2 and the AP-3 complex to facilitate protein trafficking on endosomes.
Molecular biology of the cell17(9)4027-38(2006 Sep)
Di Pietro SM,Falc?n-P?rez JM,Tenza D,Setty SR,Marks MS,Raposo G,Dell'Angelica EC

Neural progenitor genes. Germinal zone expression and analysis of genetic overlap in stem cell populations.
Developmental biology264(2)309-22(2003 Dec)
Easterday MC,Dougherty JD,Jackson RL,Ou J,Nakano I,Paucar AA,Roobini B,Dianati M,Irvin DK,Weissman IL,Terskikh AV,Geschwind DH,Kornblum HI

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Ap3s1 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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