Gene Symbol | OPRL1 |
Entrez Gene ID | 719224 |
Full Name | opioid related nociceptin receptor 1 |
Gene Type | protein-coding |
Organism | Macaca mulatta(Rhesus monkey) |
Summary | The protein encoded by this gene is a member of the 7 transmembrane-spanning G protein-coupled receptor family, and functions as a receptor for the endogenous, opioid-related neuropeptide, nociceptin/orphanin FQ. This receptor-ligand system modulates a variety of biological functions and neurobehavior, including stress responses and anxiety behavior, learning and memory, locomotor activity, and inflammatory and immune responses. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Dec 2017]. |