IL4 cDNA ORF clone, Macaca mulatta(Rhesus monkey)

Gene
Clones
gRNAs

Summary

Gene Symbol	IL4
Entrez Gene ID	574281
Full Name	interleukin 4
Gene Type	protein-coding
Organism	Macaca mulatta(Rhesus monkey)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001032904.1	NP_001028076.1	interleukin-4 precursor
XM_015140741.1	XP_014996227.1	interleukin-4 isoform X1

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Il4	NP_958427.1
Homo sapiens (human)	IL4	NP_000580.1
Pan troglodytes (chimpanzee)	IL4	NP_001011714.1
	IL4	NP_001028076.1
Bos taurus (cattle)	IL4	NP_776346.1
Mus musculus (house mouse)	Il4	NP_067258.1
Canis lupus familiaris (dog)	IL4	NP_001003159.1

Gene Ontology
Bibliography

Related articles in PubMed

Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques.
Yan G, Zhang G, Fang X, Zhang Y, Li C, Ling F, Cooper DN, Li Q, Li Y, van Gool AJ, Du H, Chen J, Chen R, Zhang P, Huang Z, Thompson JR, Meng Y, Bai Y, Wang J, Zhuo M, Wang T, Huang Y, Wei L, Li J, Wang Z, Hu H, Yang P, Le L, Stenson PD, Li B, Liu X, Ball EV, An N, Huang Q, Zhang Y, Fan W, Zhang X, Li Y, Wang W, Katze MG, Su B, Nielsen R, Yang H, Wang J, Wang X, Wang J
Nature biotechnology29(11)1019-23(2011 Oct)

Tuberculosis-induced variant IL-4 mRNA encodes a cytokine functioning as growth factor for (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate-specific Vgamma2Vdelta2 T cells.
Yuan Z, Wang R, Lee Y, Chen CY, Yu X, Wu Z, Huang D, Shen L, Chen ZW
Journal of immunology (Baltimore, Md. : 1950)182(2)811-9(2009 Jan)

Social temperament and lymph node innervation.
Sloan EK, Capitanio JP, Tarara RP, Cole SW
Brain, behavior, and immunity22(5)717-26(2008 Jul)

Replication, immunogenicity, and protective properties of live-attenuated simian immunodeficiency viruses expressing interleukin-4 or interferon-gamma.
Stahl-Hennig C, Gundlach BR, Dittmer U, ten Haaft P, Heeney J, Zou W, Emilie D, Sopper S, Uberla K
Virology305(2)473-85(2003 Jan)

Quantitation of simian cytokine and beta-chemokine mRNAs, using real-time reverse transcriptase-polymerase chain reaction: variations in expression during chronic primate lentivirus infection.
Hofmann-Lehmann R, Williams AL, Swenerton RK, Li PL, Rasmussen RA, Chenine AL, McClure HM, Ruprecht RM
AIDS research and human retroviruses18(9)627-39(2002 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Mycobacterial infections of macaques induce mRNA encoding a variant IL-4 that functions as a growth factor to promote expansion of 4-hydroxy-3-methyl-but-2-enyl pyrophosphate-specific Vgamma2Vdelta2 T effector cells.
Title: Tuberculosis-induced variant IL-4 mRNA encodes a cytokine functioning as growth factor for (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate-specific Vgamma2Vdelta2 T cells.

Low Sociable animals showed alterations in lymph node expression of the immunoregulatory cytokine genes IL4.
Title: Social temperament and lymph node innervation.

The following IL4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IL4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMb23903	NM_001032904.1 Latest version!	Macaca mulatta interleukin 4 (IL4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
OMb35130	XM_015140741.1 Latest version!	Macaca mulatta interleukin 4 (IL4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$104.30 $149.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

IL4 ( NM_001032904.1 ) cDNA ORF clone, Macaca mulatta(Rhesus monkey) -> NP_001028076.1 Macaca mulatta interleukin 4 (IL4), mRNA.

Price & Availability↑

CloneID	OMb23903
Clone ID Related Accession (Same CDS sequence)	NM_001032904.1
Accession Version	NM_001032904.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 462bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Macaca mulatta(Rhesus monkey)
Product	interleukin-4 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY376144.1. ##Evidence-Data-START## Transcript exon combination :: AY376144.1, L26027.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA4688350, SAMEA4688378 [ECO:0000350] ##Evidence-Data-END##

ATGGGTCTCA CCTCCCAACT GCTTCCCCCT CTGTTCTTCC TGCTAGCATG TGCCGGCAAC 
TTTGCCCACG GACACAACTG CCATATCGCC TTACGGGAGA TCATCGAAAC TCTGAACAGC 
CTCACAGAGC AGAAGACTCT GTGCACCAAG TTGACCATAA CGGACATCCT TGCTGCCTCC 
AAGAACACAA CTGAGAAGGA AACCTTCTGC AGGGCTGCGA CTGTGCTCCG GCAGTTCTAC 
AGCCACCATG AGAAGGACAC TCGCTGCCTG GGTGCGACTG CACAGCAGTT TCACAGGCAC 
AAGCAGCTGA TCCGATTCCT GAAACGGCTC GACAGGAACC TCTGGGGCCT GGCGGGCTTG 
AACTCCTGTC CTGTGAAGGA AGCCAGCCAG AGTACGTTGG AAGACTTCTT GGAAAGGCTA 
AAGACGATCA TGAAAGAGAA ATATTCAAAG TGTCGGAGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001028076.1
CDS	1..462
Translation	MGLTSQLLPPLFFLLACAGNFAHGHNCHIALREIIETLNSLTEQKTLCTKLTITDILAASKNTTEKETFCRAATVLRQFYSHHEKDTRCLGATAQQFHRHKQLIRFLKRLDRNLWGLAGLNSCPVKEASQSTLEDFLERLKTIMKEKYSKCRS

Target ORF information:

RefSeq Version	NM_001032904.1
Organism	Macaca mulatta(Rhesus monkey)
Definition	Macaca mulatta interleukin 4 (IL4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001032904.1

ORF Insert Sequence:

ATGGGTCTCA CCTCCCAACT GCTTCCCCCT CTGTTCTTCC TGCTAGCATG TGCCGGCAAC 
TTTGCCCACG GACACAACTG CCATATCGCC TTACGGGAGA TCATCGAAAC TCTGAACAGC 
CTCACAGAGC AGAAGACTCT GTGCACCAAG TTGACCATAA CGGACATCCT TGCTGCCTCC 
AAGAACACAA CTGAGAAGGA AACCTTCTGC AGGGCTGCGA CTGTGCTCCG GCAGTTCTAC 
AGCCACCATG AGAAGGACAC TCGCTGCCTG GGTGCGACTG CACAGCAGTT TCACAGGCAC 
AAGCAGCTGA TCCGATTCCT GAAACGGCTC GACAGGAACC TCTGGGGCCT GGCGGGCTTG 
AACTCCTGTC CTGTGAAGGA AGCCAGCCAG AGTACGTTGG AAGACTTCTT GGAAAGGCTA 
AAGACGATCA TGAAAGAGAA ATATTCAAAG TGTCGGAGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IL4 ( XM_015140741.1 ) cDNA ORF clone, Macaca mulatta(Rhesus monkey) -> XP_014996227.1 Macaca mulatta interleukin 4 (IL4), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMb35130
Clone ID Related Accession (Same CDS sequence)	XM_015140741.1
Accession Version	XM_015140741.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 414bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-12-20
Organism	Macaca mulatta(Rhesus monkey)
Product	interleukin-4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_014804958.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Macaca mulatta Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGTCTCA CCTCCCAACT GCTTCCCCCT CTGTTCTTCC TGCTAGCATG TGCCGGCAAC 
TTTGCCCACG GACACAACTG CCATATCGCC TTACGGGAGA TCATCGAAAC TCTGAACAGC 
CTCACAGAGC AGAAGAACAC AACTGAGAAG GAAACCTTCT GCAGGGCTGC GACTGTGCTC 
CGGCAGTTCT ACAGCCACCA TGAGAAGGAC ACTCGCTGCC TGGGTGCGAC TGCACAGCAG 
TTTCACAGGC ACAAGCAGCT GATCCGATTC CTGAAACGGC TCGACAGGAA CCTCTGGGGC 
CTGGCGGGCT TGAACTCCTG TCCTGTGAAG GAAGCCAGCC AGAGTACGTT GGAAGACTTC 
TTGGAAAGGC TAAAGACGAT CATGAAAGAG AAATATTCAA AGTGTCGGAG CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_014996227.1
CDS	657..1070
Translation	MGLTSQLLPPLFFLLACAGNFAHGHNCHIALREIIETLNSLTEQKNTTEKETFCRAATVLRQFYSHHEKDTRCLGATAQQFHRHKQLIRFLKRLDRNLWGLAGLNSCPVKEASQSTLEDFLERLKTIMKEKYSKCRS

Target ORF information:

RefSeq Version	XM_015140741.1
Organism	Macaca mulatta(Rhesus monkey)
Definition	Macaca mulatta interleukin 4 (IL4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_015140741.1

ORF Insert Sequence:

ATGGGTCTCA CCTCCCAACT GCTTCCCCCT CTGTTCTTCC TGCTAGCATG TGCCGGCAAC 
TTTGCCCACG GACACAACTG CCATATCGCC TTACGGGAGA TCATCGAAAC TCTGAACAGC 
CTCACAGAGC AGAAGAACAC AACTGAGAAG GAAACCTTCT GCAGGGCTGC GACTGTGCTC 
CGGCAGTTCT ACAGCCACCA TGAGAAGGAC ACTCGCTGCC TGGGTGCGAC TGCACAGCAG 
TTTCACAGGC ACAAGCAGCT GATCCGATTC CTGAAACGGC TCGACAGGAA CCTCTGGGGC 
CTGGCGGGCT TGAACTCCTG TCCTGTGAAG GAAGCCAGCC AGAGTACGTT GGAAGACTTC 
TTGGAAAGGC TAAAGACGAT CATGAAAGAG AAATATTCAA AGTGTCGGAG CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques.
Nature biotechnology29(11)1019-23(2011 Oct)
Yan G,Zhang G,Fang X,Zhang Y,Li C,Ling F,Cooper DN,Li Q,Li Y,van Gool AJ,Du H,Chen J,Chen R,Zhang P,Huang Z,Thompson JR,Meng Y,Bai Y,Wang J,Zhuo M,Wang T,Huang Y,Wei L,Li J,Wang Z,Hu H,Yang P,Le L,Stenson PD,Li B,Liu X,Ball EV,An N,Huang Q,Zhang Y,Fan W,Zhang X,Li Y,Wang W,Katze MG,Su B,Nielsen R,Yang H,Wang J,Wang X,Wang J

Tuberculosis-induced variant IL-4 mRNA encodes a cytokine functioning as growth factor for (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate-specific Vgamma2Vdelta2 T cells.
Journal of immunology (Baltimore, Md. : 1950)182(2)811-9(2009 Jan)
Yuan Z,Wang R,Lee Y,Chen CY,Yu X,Wu Z,Huang D,Shen L,Chen ZW

Social temperament and lymph node innervation.
Brain, behavior, and immunity22(5)717-26(2008 Jul)
Sloan EK,Capitanio JP,Tarara RP,Cole SW

Replication, immunogenicity, and protective properties of live-attenuated simian immunodeficiency viruses expressing interleukin-4 or interferon-gamma.
Virology305(2)473-85(2003 Jan)
Stahl-Hennig C,Gundlach BR,Dittmer U,ten Haaft P,Heeney J,Zou W,Emilie D,Sopper S,Uberla K

Quantitation of simian cytokine and beta-chemokine mRNAs, using real-time reverse transcriptase-polymerase chain reaction: variations in expression during chronic primate lentivirus infection.
AIDS research and human retroviruses18(9)627-39(2002 Jun)
Hofmann-Lehmann R,Williams AL,Swenerton RK,Li PL,Rasmussen RA,Chenine AL,McClure HM,Ruprecht RM

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IL4 cDNA ORF clone, Macaca mulatta(Rhesus monkey)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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