CBR3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CBR3
Entrez Gene ID	874
Full Name	carbonyl reductase 3
Synonyms	HEL-S-25,SDR21C2,hCBR3
General protein information	Preferred Names carbonyl reductase 3 Names carbonyl reductase [NADPH] 3 NADPH-dependent carbonyl reductase 3 carbonyl reductase (NADPH) 3 epididymis secretory protein Li 25 short chain dehydrogenase/reductase family 21C member 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 21 Map Location: 21q22.12
Summary	Carbonyl reductase 3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. The enzyme is classified as a monomeric NADPH-dependent oxidoreductase. CBR3 contains three exons spanning 11.2 kilobases and is closely linked to another carbonyl reductase gene - CBR1. [provided by RefSeq, Jul 2008].
Disorder MIM:	603608

mRNA and Protein(s)

mRNA	Protein	Name
NM_001236.4	NP_001227.1	carbonyl reductase [NADPH] 3
NM_001236.3	NP_001227.1	carbonyl reductase [NADPH] 3
XM_011529772.2	XP_011528074.1	carbonyl reductase [NADPH] 3 isoform X1

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Cbr3	NP_766635.1
Homo sapiens (human)	CBR3	NP_001227.1
Pan troglodytes (chimpanzee)	CBR3	XP_514884.2
	CBR3	XP_001084893.1
Canis lupus familiaris (dog)	CBR3	XP_544873.3
Bos taurus (cattle)	CBR3	NP_001069202.1
Rattus norvegicus (Norway rat)	Cbr3	NP_001100580.1

Gene Ontology
Bibliography

Related articles in PubMed

Risk factors for anthracycline-associated cardiotoxicity.
Reinbolt RE, Patel R, Pan X, Timmers CD, Pilarski R, Shapiro CL, Lustberg MB
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer24(5)2173-2180(2016 May)

Evidence for association of SNPs in ABCB1 and CBR3, but not RAC2, NCF4, SLC28A3 or TOP2B, with chronic cardiotoxicity in a cohort of breast cancer patients treated with anthracyclines.
Hertz DL, Caram MV, Kidwell KM, Thibert JN, Gersch C, Seewald NJ, Smerage J, Rubenfire M, Henry NL, Cooney KA, Leja M, Griggs JJ, Rae JM
Pharmacogenomics17(3)231-40(2016 Feb)

Widespread macromolecular interaction perturbations in human genetic disorders.
Sahni N, Yi S, Taipale M, Fuxman Bass JI, Coulombe-Huntington J, Yang F, Peng J, Weile J, Karras GI, Wang Y, Kov?cs IA, Kamburov A, Krykbaeva I, Lam MH, Tucker G, Khurana V, Sharma A, Liu YY, Yachie N, Zhong Q, Shen Y, Palagi A, San-Miguel A, Fan C, Balcha D, Dricot A, Jordan DM, Walsh JM, Shah AA, Yang X, Stoyanova AK, Leighton A, Calderwood MA, Jacob Y, Cusick ME, Salehi-Ashtiani K, Whitesell LJ, Sunyaev S, Berger B, Barab?si AL, Charloteaux B, Hill DE, Hao T, Roth FP, Xia Y, Walhout AJM, Lindquist S, Vidal M
Cell161(3)647-660(2015 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

No significant correlation between cardiotoxicity and SNPs within the CBR pathway. Further investigation into CBR SNPs in a larger adult sample is needed.
Title: Risk factors for anthracycline-associated cardiotoxicity.

association of SNPs in ABCB1 and CBR3 with chronic cardiotoxicity in a cohort of breast cancer patients treated with anthracyclines.
Title: Evidence for association of SNPs in ABCB1 and CBR3, but not RAC2, NCF4, SLC28A3 or TOP2B, with chronic cardiotoxicity in a cohort of breast cancer patients treated with anthracyclines.

Variants of CBR3 and GSTP1 enzymes may be associated with changes in short-term functional cardiac parameters.
Title: The relationship between changes in functional cardiac parameters following anthracycline therapy and carbonyl reductase 3 and glutathione S transferase Pi polymorphisms.

genetic polymorphism in the CBR3 gene conferred risk of type 2 diabetes and insulin resistance in Chinese. The association was probably mediated through modulation of adipogenesis.
Title: Genetic variation in the carbonyl reductase 3 gene confers risk of type 2 diabetes and insulin resistance: a potential regulator of adipogenesis.

CBR3 is a novel target gene of inflammatory stimuli; elucidation of its detailed role in inflammation deserves further investigation.
Title: Expression of human carbonyl reductase 3 (CBR3; SDR21C2) is inducible by pro-inflammatory stimuli.

The following CBR3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CBR3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu29525	NM_001236.4 Latest version!	Homo sapiens carbonyl reductase 3 (CBR3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu56680	XM_011529772.2 Latest version!	Homo sapiens carbonyl reductase 3 (CBR3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
View Old Accession Versions >>
OHu29525	NM_001236.3	Homo sapiens carbonyl reductase 3 (CBR3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CBR3 ( NM_001236.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_001227.1 Homo sapiens carbonyl reductase 3 (CBR3), mRNA.

Price & Availability↑

CloneID	OHu29525
Clone ID Related Accession (Same CDS sequence)	NM_001236.4 , NM_001236.3
Accession Version	NM_001236.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 834bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	carbonyl reductase [NADPH] 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AB041012.1 and BC002812.2. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_001236.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK223429.1, AB041012.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000290354.6/ ENSP00000290354.5 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTCGTCCT GCAGCCGCGT GGCGCTGGTG ACCGGGGCCA ACAGGGGCAT CGGCTTGGCC 
ATCGCGCGCG AACTGTGCCG ACAGTTCTCT GGGGATGTGG TGCTCACCGC GCGGGACGTG 
GCGCGGGGCC AGGCGGCCGT GCAGCAGCTG CAGGCGGAGG GCCTGAGCCC GCGCTTCCAC 
CAACTGGACA TCGACGACTT GCAGAGCATC CGCGCCCTGC GCGACTTCCT GCGCAAGGAG 
TACGGGGGGC TCAACGTACT GGTCAACAAC GCGGCCGTCG CCTTCAAGAG TGATGATCCA 
ATGCCCTTTG ACATTAAAGC TGAGATGACA CTGAAGACAA ATTTTTTTGC CACTAGAAAC 
ATGTGCAACG AGTTACTGCC GATAATGAAA CCTCATGGGA GAGTGGTGAA TATCAGTAGT 
TTGCAGTGTT TAAGGGCTTT TGAAAACTGC AGTGAAGATC TGCAGGAAAG GTTCCACAGT 
GAGACACTCA CAGAAGGAGA CCTGGTGGAT CTCATGAAAA AGTTTGTGGA GGACACAAAA 
AATGAGGTGC ATGAGAGGGA AGGCTGGCCC AACTCACCTT ATGGGGTGTC CAAGTTGGGG 
GTCACGGTCT TATCGAGGAT CCTGGCCAGG CGTCTGGATG AGAAGAGGAA AGCTGACAGG 
ATTCTGGTGA ATGCGTGCTG CCCAGGACCA GTGAAGACAG ACATGGATGG GAAAGACAGC 
ATCAGGACTG TGGAGGAGGG GGCTGAGACC CCTGTCTACT TGGCCCTCTT GCCTCCAGAT 
GCCACTGAGC CACAAGGCCA GTTGGTCCAT GACAAAGTTG TGCAAAACTG GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001227.1
CDS	115..948
Translation	MSSCSRVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAEGLSPRFHQLDIDDLQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAEMTLKTNFFATRNMCNELLPIMKPHGRVVNISSLQCLRAFENCSEDLQERFHSETLTEGDLVDLMKKFVEDTKNEVHEREGWPNSPYGVSKLGVTVLSRILARRLDEKRKADRILVNACCPGPVKTDMDGKDSIRTVEEGAETPVYLALLPPDATEPQGQLVHDKVVQNW

Target ORF information:

RefSeq Version	NM_001236.4
Organism	Homo sapiens(human)
Definition	Homo sapiens carbonyl reductase 3 (CBR3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001236.4

ORF Insert Sequence:

ATGTCGTCCT GCAGCCGCGT GGCGCTGGTG ACCGGGGCCA ACAGGGGCAT CGGCTTGGCC 
ATCGCGCGCG AACTGTGCCG ACAGTTCTCT GGGGATGTGG TGCTCACCGC GCGGGACGTG 
GCGCGGGGCC AGGCGGCCGT GCAGCAGCTG CAGGCGGAGG GCCTGAGCCC GCGCTTCCAC 
CAACTGGACA TCGACGACTT GCAGAGCATC CGCGCCCTGC GCGACTTCCT GCGCAAGGAG 
TACGGGGGGC TCAACGTACT GGTCAACAAC GCGGCCGTCG CCTTCAAGAG TGATGATCCA 
ATGCCCTTTG ACATTAAAGC TGAGATGACA CTGAAGACAA ATTTTTTTGC CACTAGAAAC 
ATGTGCAACG AGTTACTGCC GATAATGAAA CCTCATGGGA GAGTGGTGAA TATCAGTAGT 
TTGCAGTGTT TAAGGGCTTT TGAAAACTGC AGTGAAGATC TGCAGGAAAG GTTCCACAGT 
GAGACACTCA CAGAAGGAGA CCTGGTGGAT CTCATGAAAA AGTTTGTGGA GGACACAAAA 
AATGAGGTGC ATGAGAGGGA AGGCTGGCCC AACTCACCTT ATGGGGTGTC CAAGTTGGGG 
GTCACGGTCT TATCGAGGAT CCTGGCCAGG CGTCTGGATG AGAAGAGGAA AGCTGACAGG 
ATTCTGGTGA ATGCGTGCTG CCCAGGACCA GTGAAGACAG ACATGGATGG GAAAGACAGC 
ATCAGGACTG TGGAGGAGGG GGCTGAGACC CCTGTCTACT TGGCCCTCTT GCCTCCAGAT 
GCCACTGAGC CACAAGGCCA GTTGGTCCAT GACAAAGTTG TGCAAAACTG GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CBR3 ( NM_001236.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001227.1 Homo sapiens carbonyl reductase 3 (CBR3), mRNA.

Price & Availability↑

CloneID	OHu29525
Clone ID Related Accession (Same CDS sequence)	NM_001236.4 , NM_001236.3
Accession Version	NM_001236.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 834bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-30
Organism	Homo sapiens(human)
Product	carbonyl reductase [NADPH] 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AB041012.1 and BC002812.2. This sequence is a reference standard in the RefSeqGene project. On Apr 6, 2005 this sequence version replaced NM_001236.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: ERR279826.8581.1, AB041012.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCGTCCT GCAGCCGCGT GGCGCTGGTG ACCGGGGCCA ACAGGGGCAT CGGCTTGGCC 
ATCGCGCGCG AACTGTGCCG ACAGTTCTCT GGGGATGTGG TGCTCACCGC GCGGGACGTG 
GCGCGGGGCC AGGCGGCCGT GCAGCAGCTG CAGGCGGAGG GCCTGAGCCC GCGCTTCCAC 
CAACTGGACA TCGACGACTT GCAGAGCATC CGCGCCCTGC GCGACTTCCT GCGCAAGGAG 
TACGGGGGGC TCAACGTACT GGTCAACAAC GCGGCCGTCG CCTTCAAGAG TGATGATCCA 
ATGCCCTTTG ACATTAAAGC TGAGATGACA CTGAAGACAA ATTTTTTTGC CACTAGAAAC 
ATGTGCAACG AGTTACTGCC GATAATGAAA CCTCATGGGA GAGTGGTGAA TATCAGTAGT 
TTGCAGTGTT TAAGGGCTTT TGAAAACTGC AGTGAAGATC TGCAGGAAAG GTTCCACAGT 
GAGACACTCA CAGAAGGAGA CCTGGTGGAT CTCATGAAAA AGTTTGTGGA GGACACAAAA 
AATGAGGTGC ATGAGAGGGA AGGCTGGCCC AACTCACCTT ATGGGGTGTC CAAGTTGGGG 
GTCACGGTCT TATCGAGGAT CCTGGCCAGG CGTCTGGATG AGAAGAGGAA AGCTGACAGG 
ATTCTGGTGA ATGCGTGCTG CCCAGGACCA GTGAAGACAG ACATGGATGG GAAAGACAGC 
ATCAGGACTG TGGAGGAGGG GGCTGAGACC CCTGTCTACT TGGCCCTCTT GCCTCCAGAT 
GCCACTGAGC CACAAGGCCA GTTGGTCCAT GACAAAGTTG TGCAAAACTG GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001227.1
CDS	229..1062
Translation	MSSCSRVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAEGLSPRFHQLDIDDLQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAEMTLKTNFFATRNMCNELLPIMKPHGRVVNISSLQCLRAFENCSEDLQERFHSETLTEGDLVDLMKKFVEDTKNEVHEREGWPNSPYGVSKLGVTVLSRILARRLDEKRKADRILVNACCPGPVKTDMDGKDSIRTVEEGAETPVYLALLPPDATEPQGQLVHDKVVQNW

Target ORF information:

RefSeq Version	NM_001236.3
Organism	Homo sapiens(human)
Definition	Homo sapiens carbonyl reductase 3 (CBR3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001236.3

ORF Insert Sequence:

ATGTCGTCCT GCAGCCGCGT GGCGCTGGTG ACCGGGGCCA ACAGGGGCAT CGGCTTGGCC 
ATCGCGCGCG AACTGTGCCG ACAGTTCTCT GGGGATGTGG TGCTCACCGC GCGGGACGTG 
GCGCGGGGCC AGGCGGCCGT GCAGCAGCTG CAGGCGGAGG GCCTGAGCCC GCGCTTCCAC 
CAACTGGACA TCGACGACTT GCAGAGCATC CGCGCCCTGC GCGACTTCCT GCGCAAGGAG 
TACGGGGGGC TCAACGTACT GGTCAACAAC GCGGCCGTCG CCTTCAAGAG TGATGATCCA 
ATGCCCTTTG ACATTAAAGC TGAGATGACA CTGAAGACAA ATTTTTTTGC CACTAGAAAC 
ATGTGCAACG AGTTACTGCC GATAATGAAA CCTCATGGGA GAGTGGTGAA TATCAGTAGT 
TTGCAGTGTT TAAGGGCTTT TGAAAACTGC AGTGAAGATC TGCAGGAAAG GTTCCACAGT 
GAGACACTCA CAGAAGGAGA CCTGGTGGAT CTCATGAAAA AGTTTGTGGA GGACACAAAA 
AATGAGGTGC ATGAGAGGGA AGGCTGGCCC AACTCACCTT ATGGGGTGTC CAAGTTGGGG 
GTCACGGTCT TATCGAGGAT CCTGGCCAGG CGTCTGGATG AGAAGAGGAA AGCTGACAGG 
ATTCTGGTGA ATGCGTGCTG CCCAGGACCA GTGAAGACAG ACATGGATGG GAAAGACAGC 
ATCAGGACTG TGGAGGAGGG GGCTGAGACC CCTGTCTACT TGGCCCTCTT GCCTCCAGAT 
GCCACTGAGC CACAAGGCCA GTTGGTCCAT GACAAAGTTG TGCAAAACTG GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CBR3 ( XM_011529772.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011528074.1 Homo sapiens carbonyl reductase 3 (CBR3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu56680
Clone ID Related Accession (Same CDS sequence)	XM_011529772.2
Accession Version	XM_011529772.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 438bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	carbonyl reductase [NADPH] 3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000021.9) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011529772.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCGTCCT GCAGCCGCGT GGCGCTGGTG ACCGGGGCCA ACAGGGGCAT CGGCTTGGCC 
ATCGCGCGCG AACTGTGCCG ACAGTTCTCT GGGGATGTGG TGCTCACCGC GCGGGACGTG 
GCGCGGGGCC AGGCGGCCGT GCAGCAGCTG CAGGCGGAGG GCCTGAGCCC GCGCTTCCAC 
CAACTGGACA TCGACGACTT GCAGAGCATC CGCGCCCTGC GCGACTTCCT GCGCAAGGAG 
TACGGGGGGC TCAACGTACT GGTCAACAAC GCGGCCGTCG CCTTCAAGAG TGATGATCCA 
ATGCCCTTTG ACATTAAAGC TGAGATGACA CTGAAGACAA ATTTTTTTGC CACTAGAAAC 
ATGTGCAACG AGTTACTGCC GATAATGAAA CCTCATGCCG CCAAGTTTCT GAGAACAAAG 
CTGTTTAGAA AGCAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011528074.1
CDS	293..730
Translation	MSSCSRVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAEGLSPRFHQLDIDDLQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAEMTLKTNFFATRNMCNELLPIMKPHAAKFLRTKLFRKQ

Target ORF information:

RefSeq Version	XM_011529772.2
Organism	Homo sapiens(human)
Definition	Homo sapiens carbonyl reductase 3 (CBR3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011529772.2

ORF Insert Sequence:

ATGTCGTCCT GCAGCCGCGT GGCGCTGGTG ACCGGGGCCA ACAGGGGCAT CGGCTTGGCC 
ATCGCGCGCG AACTGTGCCG ACAGTTCTCT GGGGATGTGG TGCTCACCGC GCGGGACGTG 
GCGCGGGGCC AGGCGGCCGT GCAGCAGCTG CAGGCGGAGG GCCTGAGCCC GCGCTTCCAC 
CAACTGGACA TCGACGACTT GCAGAGCATC CGCGCCCTGC GCGACTTCCT GCGCAAGGAG 
TACGGGGGGC TCAACGTACT GGTCAACAAC GCGGCCGTCG CCTTCAAGAG TGATGATCCA 
ATGCCCTTTG ACATTAAAGC TGAGATGACA CTGAAGACAA ATTTTTTTGC CACTAGAAAC 
ATGTGCAACG AGTTACTGCC GATAATGAAA CCTCATGCCG CCAAGTTTCT GAGAACAAAG 
CTGTTTAGAA AGCAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Risk factors for anthracycline-associated cardiotoxicity.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer24(5)2173-2180(2016 May)
Reinbolt RE,Patel R,Pan X,Timmers CD,Pilarski R,Shapiro CL,Lustberg MB

Evidence for association of SNPs in ABCB1 and CBR3, but not RAC2, NCF4, SLC28A3 or TOP2B, with chronic cardiotoxicity in a cohort of breast cancer patients treated with anthracyclines.
Pharmacogenomics17(3)231-40(2016 Feb)
Hertz DL,Caram MV,Kidwell KM,Thibert JN,Gersch C,Seewald NJ,Smerage J,Rubenfire M,Henry NL,Cooney KA,Leja M,Griggs JJ,Rae JM

Widespread macromolecular interaction perturbations in human genetic disorders.
Cell161(3)647-660(2015 Apr)
Sahni N,Yi S,Taipale M,Fuxman Bass JI,Coulombe-Huntington J,Yang F,Peng J,Weile J,Karras GI,Wang Y,Kov?cs IA,Kamburov A,Krykbaeva I,Lam MH,Tucker G,Khurana V,Sharma A,Liu YY,Yachie N,Zhong Q,Shen Y,Palagi A,San-Miguel A,Fan C,Balcha D,Dricot A,Jordan DM,Walsh JM,Shah AA,Yang X,Stoyanova AK,Leighton A,Calderwood MA,Jacob Y,Cusick ME,Salehi-Ashtiani K,Whitesell LJ,Sunyaev S,Berger B,Barab?si AL,Charloteaux B,Hill DE,Hao T,Roth FP,Xia Y,Walhout AJM,Lindquist S,Vidal M

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CBR3 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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